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Joshua C. Canzoneri, Ph.D. - Publications

Affiliations: 
2012 Chemistry and Biochemistry Georgia Institute of Technology, Atlanta, GA 
Area:
Pharmaceutical Chemistry, Biochemistry, Physical Chemistry
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18 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Zhu B, Lindsey A, Li N, Lee K, Ramirez-Alcantara V, Canzoneri JC, Fajardo A, Madeira da Silva L, Thomas M, Piazza JT, Yet L, Eberhardt BT, Gurpinar E, Otali D, Grizzle W, et al. Phosphodiesterase 10A is overexpressed in lung tumor cells and inhibitors selectively suppress growth by blocking β-catenin and MAPK signaling. Oncotarget. 8: 69264-69280. PMID 29050202 DOI: 10.18632/Oncotarget.20566  0.322
2016 Abdel-Rahman HM, Abdel-Aziz M, Tinsley HN, Gary BD, Canzoneri JC, Piazza GA. Design and Synthesis of Substituted Pyridazinone-1-Acetylhydrazones as Novel Phosphodiesterase 4 Inhibitors. Archiv Der Pharmazie. 349: 104-11. PMID 26686665 DOI: 10.1002/Ardp.201500363  0.43
2016 Keeton AB, Zhu B, Lee KJ, Canzoneri JC, Sigler SC, Lindsey AS, Ramirez-Alcantara V, Barnes L, Mattox TE, McConnell K, Berry KL, Valiyaveettil J, Chen X, Boyd MR, Piazza GA. Abstract 326: Discovery and in vitro and in vivo characterization of a novel, small-molecule Ras inhibitor class Cancer Research. 76: 326-326. DOI: 10.1158/1538-7445.Am2016-326  0.327
2015 Elhady AK, Sigler SC, Noureldin N, Canzoneri JC, Ahmed NS, Piazza GA, Abadi AH. Structure-Based Design of Novel Tetrahydro-Beta-Carboline Derivatives with a Hydrophilic Side Chain as Potential Phosphodiesterase Inhibitors. Scientia Pharmaceutica. 84: 428-446. PMID 28117310 DOI: 10.3390/Scipharm84030428  0.36
2015 Hassaan EA, Sigler SC, Ibrahim TM, Lee KJ, Cichon LK, Gary BD, Canzoneri JC, Piazza GA, Abadi AH. Mining ZINC Database to Discover Potential Phosphodiesterase 9 Inhibitors Using Structure-Based Drug Design Approach. Medicinal Chemistry (Shariqah (United Arab Emirates)). PMID 26648332 DOI: 10.2174/1573406412666151204002836  0.471
2015 Li N, Chen X, Zhu B, Ramírez-Alcántara V, Canzoneri JC, Lee K, Sigler S, Gary B, Li Y, Zhang W, Moyer MP, Salter EA, Wierzbicki A, Keeton AB, Piazza GA. Suppression of β-catenin/TCF transcriptional activity and colon tumor cell growth by dual inhibition of PDE5 and 10. Oncotarget. PMID 26299804 DOI: 10.18632/Oncotarget.4741  0.444
2015 Li N, Lee K, Xi Y, Zhu B, Gary BD, Ramírez-Alcántara V, Gurpinar E, Canzoneri JC, Fajardo A, Sigler S, Piazza JT, Chen X, Andrews J, Thomas M, Lu W, et al. Phosphodiesterase 10A: a novel target for selective inhibition of colon tumor cell growth and β-catenin-dependent TCF transcriptional activity. Oncogene. 34: 1499-509. PMID 24704829 DOI: 10.1038/Onc.2014.94  0.38
2015 Li N, Chen X, Zhu B, Ramírez-Alcántara V, Canzoneri JC, Lee K, Sigler S, Gary B, Li Y, Zhang W, Moyer MP, Salter EA, Wierzbicki A, Keeton AB, Piazza GA. Suppression of ß-catenin/TCF transcriptional activity and colon tumor cell growth by dual inhibition of PDE5 and 10 Oncotarget. 6: 27403-27415. DOI: 10.18632/oncotarget.4741  0.353
2015 Canzoneri JC, Chen X, Keeton AB, Lee K, Gary B, Butler EB, Grizzle WE, Wilson L, Barnes S, Boyd MR, Piazza GA. Abstract 701: A novel class of Ras selective inhibitors Cancer Research. 75: 701-701. DOI: 10.1158/1538-7445.Am2015-701  0.345
2014 Washington AZ, Benicewicz DB, Canzoneri JC, Fagan CE, Mwakwari SC, Maehigashi T, Dunham CM, Oyelere AK. Macrolide-peptide conjugates as probes of the path of travel of the nascent peptides through the ribosome. Acs Chemical Biology. 9: 2621-31. PMID 25198768 DOI: 10.1021/Cb5003224  0.561
2014 Abdel-Rahman HM, Abdel-Aziz M, Canzoneri JC, Gary BD, Piazza GA. Novel quinazolin-4(3H)-one/Schiff base hybrids as antiproliferative and phosphodiesterase 4 inhibitors: design, synthesis, and docking studies. Archiv Der Pharmazie. 347: 650-7. PMID 24985336 DOI: 10.1002/Ardp.201400083  0.396
2014 Chen X, Lee KJ, Gary BD, Canzoneri JC, Fajardo AM, Sigler SC, Ramirez-Alcantara V, Zhu B, Piazza GA, Keeton AB. Abstract B39: A novel series of substituted indene derivatives that potently and selectively inhibit growth of tumor cells harboring mutant Ras Molecular Cancer Research. 12. DOI: 10.1158/1557-3125.Rasonc14-B39  0.355
2014 Li N, Lee K, Xi Y, Zhu B, Gary BD, Ramírez-Alcántara V, Gurpinar E, Canzoneri JC, Fajardo A, Sigler S, Piazza JT, Chen X, Andrews J, Lu W, Li Y, et al. Abstract 1773: Phosphodiesterase 10A: A novel target for selective inhibition of colon tumor cell growth and Wnt/β-catenin signaling Cancer Research. 74: 1773-1773. DOI: 10.1158/1538-7445.Am2014-1773  0.367
2013 Guerrant W, Patil V, Canzoneri JC, Yao LP, Hood R, Oyelere AK. Dual-acting histone deacetylase-topoisomerase I inhibitors. Bioorganic & Medicinal Chemistry Letters. 23: 3283-7. PMID 23622981 DOI: 10.1016/J.Bmcl.2013.03.108  0.641
2012 Patil V, Canzoneri JC, Samatov TR, Lührmann R, Oyelere AK. Molecular architecture of zinc chelating small molecules that inhibit spliceosome assembly at an early stage. Rna (New York, N.Y.). 18: 1605-11. PMID 22832025 DOI: 10.1261/Rna.034819.112  0.664
2012 Guerrant W, Patil V, Canzoneri JC, Oyelere AK. Dual targeting of histone deacetylase and topoisomerase II with novel bifunctional inhibitors. Journal of Medicinal Chemistry. 55: 1465-77. PMID 22260166 DOI: 10.1021/Jm200799P  0.641
2009 Canzoneri JC, Chen PC, Oyelere AK. Design and synthesis of novel histone deacetylase inhibitor derived from nuclear localization signal peptide. Bioorganic & Medicinal Chemistry Letters. 19: 6588-90. PMID 19854643 DOI: 10.1016/J.Bmcl.2009.10.028  0.699
2008 Canzoneri JC, Oyelere AK. Interaction of anthracyclines with iron responsive element mRNAs. Nucleic Acids Research. 36: 6825-34. PMID 18953029 DOI: 10.1093/Nar/Gkn774  0.555
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