| Year |
Citation |
Score |
| 2024 |
Burnett SB, Culver AM, Simon TA, Rowson T, Frederick K, Palmer K, Murray SA, Davis SW, Patel RC. A frameshift mutation in the murine gene causes dystonia and exhibits abnormal cerebellar development and reduced eIF2α phosphorylation. Biorxiv : the Preprint Server For Biology. PMID 38895245 DOI: 10.1101/2024.06.04.597421 |
0.304 |
|
| 2023 |
Frederick K, Patel RC. Luteolin protects DYT- cells from apoptosis by suppressing PKR activation. Frontiers in Pharmacology. 14: 1118725. PMID 36874028 DOI: 10.3389/fphar.2023.1118725 |
0.526 |
|
| 2022 |
Vaughn LS, Frederick K, Burnett SB, Sharma N, Bragg DC, Camargos S, Cardoso F, Patel RC. DYT- Mutation P222L Enhances PACT's Stimulatory Activity on Type I Interferon Induction. Biomolecules. 12. PMID 35625640 DOI: 10.3390/biom12050713 |
0.394 |
|
| 2021 |
Ukhueduan B, Chukwurah E, Patel RC. Regulation of PKR activation and apoptosis during oxidative stress by TRBP phosphorylation. The International Journal of Biochemistry & Cell Biology. 137: 106030. PMID 34174402 DOI: 10.1016/j.biocel.2021.106030 |
0.547 |
|
| 2021 |
Vaughn LS, Chukwurah E, Patel RC. Opposite actions of two dsRNA-binding proteins PACT and TRBP on RIG-I mediated signaling. The Biochemical Journal. PMID 33459340 DOI: 10.1042/BCJ20200987 |
0.407 |
|
| 2020 |
Burnett SB, Vaughn LS, Sharma N, Kulkarni R, Patel RC. Dystonia 16 (DYT16) mutations in PACT cause dysregulated PKR activation and eIF2α signaling leading to a compromised stress response. Neurobiology of Disease. 146: 105135. PMID 33049316 DOI: 10.1016/j.nbd.2020.105135 |
0.501 |
|
| 2019 |
Burnett SB, Vaughn LS, Strom JM, Francois A, Patel RC. A truncated PACT protein resulting from a frameshift mutation reported in movement disorder DYT16 triggers caspase activation and apoptosis. Journal of Cellular Biochemistry. PMID 31246344 DOI: 10.1002/Jcb.29223 |
0.586 |
|
| 2019 |
Dey A, Patel R, Smalley T, Ratnayake WS, Islam A, Acevedo-Duncan M. Abstract 244: Inhibition of atypical PKC signaling enhances the sensitivity of glioblastoma cells towards Temozolomide therapy Cancer Research. DOI: 10.1158/1538-7445.Sabcs18-244 |
0.324 |
|
| 2019 |
Smalley T, Patel R, Acevedo-Duncan M. Abstract 1776: An investigation of the effects of the atypical protein kinase C-ζinhibitor ζ-Stat on clear cell carcinoma ovarian cancer proliferation and invasion Cancer Research. DOI: 10.1158/1538-7445.Sabcs18-1776 |
0.375 |
|
| 2018 |
Chukwurah E, Patel RC. Stress-induced TRBP phosphorylation enhances its interaction with PKR to regulate cellular survival. Scientific Reports. 8: 1020. PMID 29348664 DOI: 10.1038/S41598-018-19360-8 |
0.635 |
|
| 2018 |
Islam SMA, Khalid KM, Bommareddy RR, Patel R, Acevedo-Duncan M. Abstract 5155: The modulation of actin dynamics via atypical protein kinase-C activated cofilin regulates migration of colorectal cancer cells Tumor Biology. DOI: 10.1158/1538-7445.Am2018-5155 |
0.428 |
|
| 2018 |
Ratnayake WS, Apostolatos AH, Apostolatos CA, Dey A, Patel R, Acevedo-Duncan M. Abstract 2022: Oncogenic protein kinase Cι drives melanoma cell epithelial-mesenchymal transition by activating vimentin through Par6/RhoA signaling Tumor Biology. DOI: 10.1158/1538-7445.Am2018-2022 |
0.464 |
|
| 2017 |
Chukwurah E, Willingham V, Singh M, Castillo-Azofeifa D, Patel RC. Contribution of the two dsRBM motifs to the double-stranded RNA binding and protein interactions of PACT. Journal of Cellular Biochemistry. PMID 29231267 DOI: 10.1002/Jcb.26561 |
0.834 |
|
| 2017 |
Dabo S, Maillard P, Collados Rodriguez M, Hansen MD, Mazouz S, Bigot DJ, Tible M, Janvier G, Helynck O, Cassonnet P, Jacob Y, Bellalou J, Gatignol A, Patel RC, Hugon J, et al. Inhibition of the inflammatory response to stress by targeting interaction between PKR and its cellular activator PACT. Scientific Reports. 7: 16129. PMID 29170442 DOI: 10.1038/S41598-017-16089-8 |
0.462 |
|
| 2017 |
Chukwurah E, Handy I, Patel RC. ADAR1 and PACT contribute to efficient translation of transcripts containing HIV-1 trans-activating response (TAR) element. The Biochemical Journal. PMID 28167698 DOI: 10.1042/Bcj20160964 |
0.457 |
|
| 2016 |
Schumpert CA, Anderson C, Dudycha JL, Patel RC. Involvement of Daphnia pulicaria Sir2 in regulating stress response and lifespan. Aging. 8: 402-17. PMID 26978617 |
0.314 |
|
| 2015 |
Vaughn LS, Bragg DC, Sharma N, Camargos S, Cardoso F, Patel RC. Altered Activation of Protein Kinase PKR and Enhanced Apoptosis in Dystonia Cells Carrying a Mutation in PKR Activator Protein PACT. The Journal of Biological Chemistry. 290: 22543-57. PMID 26231208 DOI: 10.1074/Jbc.M115.669408 |
0.59 |
|
| 2015 |
Schumpert C, Nelson J, Kim E, Dudycha JL, Patel RC. Telomerase activity and telomere length in Daphnia. Plos One. 10: e0127196. PMID 25962144 DOI: 10.1371/Journal.Pone.0127196 |
0.315 |
|
| 2015 |
Chukwurah E, Radetskyy R, Daher A, Gatignol A, Patel RC. ID: 214 Cytokine. 76: 104. DOI: 10.1016/J.Cyto.2015.08.218 |
0.472 |
|
| 2015 |
Vaughn LS, Patel RC. ID: 104 Cytokine. 76: 84-85. DOI: 10.1016/J.Cyto.2015.08.131 |
0.477 |
|
| 2014 |
Schumpert C, Handy I, Dudycha JL, Patel RC. Relationship between heat shock protein 70 expression and life span in Daphnia. Mechanisms of Ageing and Development. 139: 1-10. PMID 24814302 DOI: 10.1016/J.Mad.2014.04.001 |
0.361 |
|
| 2014 |
Vaughn LS, Snee B, Patel RC. Inhibition of PKR protects against tunicamycin-induced apoptosis in neuroblastoma cells. Gene. 536: 90-6. PMID 24334130 DOI: 10.1016/J.Gene.2013.11.074 |
0.542 |
|
| 2013 |
Clerzius G, Shaw E, Daher A, Burugu S, Gélinas JF, Ear T, Sinck L, Routy JP, Mouland AJ, Patel RC, Gatignol A. The PKR activator, PACT, becomes a PKR inhibitor during HIV-1 replication. Retrovirology. 10: 96. PMID 24020926 DOI: 10.1186/1742-4690-10-96 |
0.499 |
|
| 2013 |
Patel R, Apostolatos A, Carter G, Ajmo J, Gali M, Cooper DR, You M, Bisht KS, Patel NA. Protein kinase C δ (PKCδ) splice variants modulate apoptosis pathway in 3T3L1 cells during adipogenesis: identification of PKCδII inhibitor. The Journal of Biological Chemistry. 288: 26834-46. PMID 23902767 DOI: 10.1074/Jbc.M113.482638 |
0.448 |
|
| 2013 |
Handy I, Patel RC. STAT1 requirement for PKR-induced cell cycle arrest in vascular smooth muscle cells in response to heparin. Gene. 524: 15-21. PMID 23597922 DOI: 10.1016/J.Gene.2013.03.124 |
0.566 |
|
| 2013 |
Clerzius G, Shaw E, Daher A, Burugu S, Gélinas J, Routy J, Patel RC, Gatignol A. HIV-1 replication changes the function of the PKR activator PACT Retrovirology. 10: P35. DOI: 10.1186/1742-4690-10-S1-P35 |
0.354 |
|
| 2013 |
Vaughn LS, Bragg DC, Sharma N, Camargos S, Cardoso F, Patel RC. 268 Cytokine. 63: 306-307. DOI: 10.1016/J.Cyto.2013.06.271 |
0.549 |
|
| 2012 |
Mittelstadt ML, Patel RC. AP-1 mediated transcriptional repression of matrix metalloproteinase-9 by recruitment of histone deacetylase 1 in response to interferon β. Plos One. 7: e42152. PMID 22879913 DOI: 10.1371/Journal.Pone.0042152 |
0.728 |
|
| 2012 |
Singh M, Patel RC. Increased interaction between PACT molecules in response to stress signals is required for PKR activation. Journal of Cellular Biochemistry. 113: 2754-64. PMID 22473766 DOI: 10.1002/Jcb.24152 |
0.834 |
|
| 2011 |
Singh M, Castillo D, Patel CV, Patel RC. Stress-induced phosphorylation of PACT reduces its interaction with TRBP and leads to PKR activation. Biochemistry. 50: 4550-60. PMID 21526770 DOI: 10.1021/Bi200104H |
0.838 |
|
| 2011 |
Pillai P, Desai S, Patel R, Sajan M, Farese R, Ostrov D, Acevedo-Duncan M. A novel PKC-ι inhibitor abrogates cell proliferation and induces apoptosis in neuroblastoma. The International Journal of Biochemistry & Cell Biology. 43: 784-94. PMID 21315177 DOI: 10.1016/J.Biocel.2011.02.002 |
0.385 |
|
| 2011 |
Singh M, Handy I, Patel RC. PS2-065. Effect of DYT16 (PACT) mutations on interferon-induced protein kinase PKR and endoplasmic reticulum (ER) stress response pathway Cytokine. 56: 82. DOI: 10.1016/J.Cyto.2011.07.227 |
0.791 |
|
| 2010 |
Singh M, Castillo D, Patel CV, Patel RC. PS3-26 Phosphorylation of PACT at specific serines in response to stress signals regulates PKR activation by reducing PACT’s interaction with TRBP Cytokine. 52: 87. DOI: 10.1016/J.Cyto.2010.07.365 |
0.805 |
|
| 2009 |
Singh M, Fowlkes V, Handy I, Patel CV, Patel RC. Essential role of PACT-mediated PKR activation in tunicamycin-induced apoptosis. Journal of Molecular Biology. 385: 457-68. PMID 19007793 DOI: 10.1016/J.Jmb.2008.10.068 |
0.822 |
|
| 2009 |
Daher A, Laraki G, Singh M, Melendez-Peña CE, Bannwarth S, Peters AH, Meurs EF, Braun RE, Patel RC, Gatignol A. TRBP control of PACT-induced phosphorylation of protein kinase R is reversed by stress. Molecular and Cellular Biology. 29: 254-65. PMID 18936160 DOI: 10.1128/Mcb.01030-08 |
0.836 |
|
| 2008 |
Mittelstadt M, Frump A, Khuu T, Fowlkes V, Handy I, Patel CV, Patel RC. Interaction of human tRNA-dihydrouridine synthase-2 with interferon-induced protein kinase PKR. Nucleic Acids Research. 36: 998-1008. PMID 18096616 DOI: 10.1093/Nar/Gkm1129 |
0.81 |
|
| 2008 |
Trivedi CM, Patel RC, Patel CV. Differential regulation of HOXA9 expression by nuclear factor kappa B (NF-kappaB) and HOXA9. Gene. 408: 187-95. PMID 18068911 DOI: 10.1016/J.Gene.2007.11.001 |
0.691 |
|
| 2007 |
Trivedi CM, Patel RC, Patel CV. Homeobox gene HOXA9 inhibits nuclear factor-kappa B dependent activation of endothelium. Atherosclerosis. 195: e50-60. PMID 17586512 DOI: 10.1016/J.Atherosclerosis.2007.04.055 |
0.699 |
|
| 2007 |
Fasciano S, Kaufman A, Patel RC. Expression of PACT is regulated by Sp1 transcription factor. Gene. 388: 74-82. PMID 17125937 DOI: 10.1016/J.Gene.2006.10.003 |
0.779 |
|
| 2005 |
Fasciano S, Hutchins B, Handy I, Patel RC. Identification of the heparin-binding domains of the interferon-induced protein kinase, PKR. The Febs Journal. 272: 1425-39. PMID 15752359 DOI: 10.1111/J.1742-4658.2005.04575.X |
0.788 |
|
| 2005 |
Fasciano S, Patel RC, Handy I, Patel CV. Regulation of vascular smooth muscle proliferation by heparin: inhibition of cyclin-dependent kinase 2 activity by p27(kip1). The Journal of Biological Chemistry. 280: 15682-9. PMID 15731113 DOI: 10.1074/Jbc.M411458200 |
0.755 |
|
| 2005 |
Bicaku E, Patel R, Acevedo-Duncan M. Cyclin-dependent kinase activating kinase/Cdk7 co-localizes with PKC-iota in human glioma cells. Tissue & Cell. 37: 53-8. PMID 15695176 DOI: 10.1016/J.Tice.2004.10.004 |
0.305 |
|
| 2004 |
Acevedo-Duncan M, Russell C, Patel S, Patel R. Aloe-emodin modulates PKC isozymes, inhibits proliferation, and induces apoptosis in U-373MG glioma cells. International Immunopharmacology. 4: 1775-84. PMID 15531293 DOI: 10.1016/J.Intimp.2004.07.012 |
0.301 |
|
| 2003 |
Gupta V, Huang X, Patel RC. The carboxy-terminal, M3 motifs of PACT and TRBP have opposite effects on PKR activity. Virology. 315: 283-91. PMID 14585331 DOI: 10.1016/S0042-6822(03)00589-0 |
0.677 |
|
| 2002 |
Patel RC, Handy I, Patel CV. Contribution of double-stranded RNA-activated protein kinase toward antiproliferative actions of heparin on vascular smooth muscle cells. Arteriosclerosis, Thrombosis, and Vascular Biology. 22: 1439-44. PMID 12231563 DOI: 10.1161/01.Atv.0000028817.20351.Fe |
0.491 |
|
| 2002 |
Gupta V, Patel RC. Proapoptotic protein PACT is expressed at high levels in colonic epithelial cells in mice. American Journal of Physiology. Gastrointestinal and Liver Physiology. 283: G801-8. PMID 12181197 DOI: 10.1152/Ajpgi.00498.2001 |
0.599 |
|
| 2002 |
Huang X, Hutchins B, Patel RC. The C-terminal, third conserved motif of the protein activator PACT plays an essential role in the activation of double-stranded-RNA-dependent protein kinase (PKR). The Biochemical Journal. 366: 175-86. PMID 11985496 DOI: 10.1042/Bj20020204 |
0.688 |
|
| 2000 |
Edgerton M, Koshlukova SE, Araujo MWB, Patel RC, Dong J, Bruenn JA. Salivary histatin 5 and human neutrophil defensin 1 kill Candida albicans via shared pathways Antimicrobial Agents and Chemotherapy. 44: 3310-3316. PMID 11083633 DOI: 10.1128/Aac.44.12.3310-3316.2000 |
0.387 |
|
| 2000 |
Patel CV, Handy I, Goldsmith T, Patel RC. PACT, a stress-modulated cellular activator of interferon-induced double-stranded RNA-activated protein kinase, PKR Journal of Biological Chemistry. 275: 37993-37998. PMID 10988289 DOI: 10.1074/Jbc.M004762200 |
0.645 |
|
| 1999 |
Patel RC, Vestal DJ, Xu Z, Bandyopadhyay S, Guo W, Erme SM, Williams BR, Sen GC. DRBP76, a double-stranded RNA-binding nuclear protein, is phosphorylated by the interferon-induced protein kinase, PKR. The Journal of Biological Chemistry. 274: 20432-7. PMID 10400669 DOI: 10.1074/Jbc.274.29.20432 |
0.549 |
|
| 1998 |
Patel RC, Sen GC. Requirement of PKR dimerization mediated by specific hydrophobic residues for its activation by double-stranded RNA and its antigrowth effects in yeast Molecular and Cellular Biology. 18: 7009-7019. PMID 9819388 DOI: 10.1128/Mcb.18.12.7009 |
0.481 |
|
| 1998 |
Leaman DW, Salvekar A, Patel R, Sen GC, Stark GR. A mutant cell line defective in response to double-stranded RNA and in regulating basal expression of interferon-stimulated genes Proceedings of the National Academy of Sciences of the United States of America. 95: 9442-9447. PMID 9689099 DOI: 10.1073/Pnas.95.16.9442 |
0.5 |
|
| 1998 |
Patel RC, Sen GC. PACT, a protein activator of the interferon-induced protein kinase, PKR Embo Journal. 17: 4379-4390. PMID 9687506 DOI: 10.1093/Emboj/17.15.4379 |
0.589 |
|
| 1996 |
Patel RC, Stanton P, Sen GC. Specific mutations near the amino terminus of double-stranded RNA- dependent protein kinase (PKR) differentially affect its double-stranded RNA binding and dimerization properties Journal of Biological Chemistry. 271: 25657-25663. PMID 8810342 DOI: 10.1074/Jbc.271.41.25657 |
0.501 |
|
| 1995 |
Patel RC, Stanton P, Mcmillan NMJ, Williams BRG, Sen GC. The interferon-inducible double-stranded RNA-activated protein kinase self-associates in vitro and in vivo Proceedings of the National Academy of Sciences of the United States of America. 92: 8283-8287. PMID 7545299 DOI: 10.1073/Pnas.92.18.8283 |
0.576 |
|
| 1995 |
Desai SY, Patel RC, Sen GC, Malhotra P, Ghadge GD, Thimmapaya B. Activation of interferon-inducible 2′-5′ oligoadenylate synthetase by adenoviral VAI RNA Journal of Biological Chemistry. 270: 3454-3461. PMID 7531709 DOI: 10.1074/Jbc.270.7.3454 |
0.483 |
|
| 1992 |
Patel RC, Sen GC. Construction and expression of an enzymatically active human-mouse chimeric double-stranded RNA-dependent protein kinase Journal of Interferon Research. 12: 389-393. PMID 1358989 DOI: 10.1089/Jir.1992.12.389 |
0.504 |
|
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