Year |
Citation |
Score |
2020 |
Owais A, Mishra RK, Kiyokawa H. The HECT E3 Ligase E6AP/UBE3A as a Therapeutic Target in Cancer and Neurological Disorders. Cancers. 12. PMID 32751183 DOI: 10.3390/Cancers12082108 |
0.318 |
|
2018 |
Roof AK, Jirawatnotai S, Trudeau T, Kuzyk C, Wierman ME, Kiyokawa H, Gutierrez-Hartmann A. The balance of PI3K and ERK signaling is dysregulated in prolactinoma and modulated by dopamine. Endocrinology. PMID 29726995 DOI: 10.1210/En.2017-03135 |
0.692 |
|
2018 |
Bhuripanyo K, Wang Y, Liu X, Zhou L, Liu R, Duong D, Zhao B, Bi Y, Zhou H, Chen G, Seyfried NT, Chazin WJ, Kiyokawa H, Yin J. Identifying the substrate proteins of U-box E3s E4B and CHIP by orthogonal ubiquitin transfer. Science Advances. 4: e1701393. PMID 29326975 DOI: 10.1126/Sciadv.1701393 |
0.364 |
|
2017 |
Gillam MP, Ku CR, Lee YJ, Kim J, Kim SH, Lee SJ, Hwang B, Koo J, Kineman RD, Kiyokawa H, Lee EJ. Somatotroph-Specific Aip-Deficient Mice Display Pretumorigenic Alterations in Cell-Cycle Signaling. Journal of the Endocrine Society. 1: 78-95. PMID 29264469 DOI: 10.1210/Js.2016-1004 |
0.454 |
|
2017 |
Wang Y, Liu X, Zhou L, Duong D, Bhuripanyo K, Zhao B, Zhou H, Liu R, Bi Y, Kiyokawa H, Yin J. Identifying the ubiquitination targets of E6AP by orthogonal ubiquitin transfer. Nature Communications. 8: 2232. PMID 29263404 DOI: 10.1038/S41467-017-01974-7 |
0.365 |
|
2017 |
Liu X, Sun L, Gursel DB, Cheng C, Huang S, Rademaker AW, Khan SA, Yin J, Kiyokawa H. The non-canonical ubiquitin activating enzyme UBA6 suppresses epithelial-mesenchymal transition of mammary epithelial cells. Oncotarget. 8: 87480-87493. PMID 29152096 DOI: 10.18632/Oncotarget.20900 |
0.465 |
|
2017 |
Liu X, Zhao B, Sun L, Bhuripanyo K, Wang Y, Bi Y, Davuluri RV, Duong DM, Nanavati D, Yin J, Kiyokawa H. Orthogonal ubiquitin transfer identifies ubiquitination substrates under differential control by the two ubiquitin activating enzymes. Nature Communications. 8: 14286. PMID 28134249 DOI: 10.1038/Ncomms14286 |
0.334 |
|
2015 |
Gillam MP, Nimbalkar D, Sun L, Christov K, Ray D, Kaldis P, Liu X, Kiyokawa H. MEN1 tumorigenesis in the pituitary and pancreatic islet requires CDK4 but not Cdk2 Oncogene. 34: 932-938. DOI: 10.1038/Onc.2014.3 |
0.468 |
|
2014 |
Bai F, Chan HL, Smith MD, Kiyokawa H, Pei XH. p19Ink4d is a tumor suppressor and controls pituitary anterior lobe cell proliferation. Molecular and Cellular Biology. 34: 2121-34. PMID 24687853 DOI: 10.1128/Mcb.01363-13 |
0.459 |
|
2014 |
Liu X, Gu X, Sun L, Flowers AB, Rademaker AW, Zhou Y, Kiyokawa H. Downregulation of Smurf2, a tumor-suppressive ubiquitin ligase, in triple-negative breast cancers: involvement of the RB-microRNA axis. Bmc Cancer. 14: 57. PMID 24485087 DOI: 10.1186/1471-2407-14-57 |
0.362 |
|
2012 |
Masyuk TV, Radtke BN, Stroope AJ, Banales JM, Masyuk AI, Gradilone SA, Gajdos GB, Chandok N, Bakeberg JL, Ward CJ, Ritman EL, Kiyokawa H, LaRusso NF. Inhibition of Cdc25A suppresses hepato-renal cystogenesis in rodent models of polycystic kidney and liver disease. Gastroenterology. 142: 622-633.e4. PMID 22155366 DOI: 10.1053/J.Gastro.2011.11.036 |
0.342 |
|
2011 |
Ray D, Ahsan A, Helman A, Chen G, Hegde A, Gurjar SR, Zhao L, Kiyokawa H, Beer DG, Lawrence TS, Nyati MK. Regulation of EGFR protein stability by the HECT-type ubiquitin ligase SMURF2. Neoplasia (New York, N.Y.). 13: 570-8. PMID 21750651 DOI: 10.1593/Neo.11632 |
0.354 |
|
2011 |
Ray D, Terao Y, Christov K, Kaldis P, Kiyokawa H. Cdk2-null mice are resistant to ErbB-2-induced mammary tumorigenesis. Neoplasia (New York, N.Y.). 13: 439-44. PMID 21532884 DOI: 10.1593/Neo.101704 |
0.523 |
|
2011 |
Beukelaers P, Vandenbosch R, Caron N, Nguyen L, Belachew S, Moonen G, Kiyokawa H, Barbacid M, Santamaria D, Malgrange B. Cdk6-dependent regulation of G(1) length controls adult neurogenesis. Stem Cells (Dayton, Ohio). 29: 713-24. PMID 21319271 DOI: 10.1002/Stem.616 |
0.349 |
|
2010 |
Taylor W, Mathias A, Ali A, Ke H, Stoynev N, Shilkaitis A, Green A, Kiyokawa H, Christov K. p27(Kip1) deficiency promotes prostate carcinogenesis but does not affect the efficacy of retinoids in suppressing the neoplastic process. Bmc Cancer. 10: 541. PMID 20932324 DOI: 10.1186/1471-2407-10-541 |
0.406 |
|
2010 |
Moore FE, Osmundson EC, Koblinski J, Pugacheva E, Golemis EA, Ray D, Kiyokawa H. The WW-HECT protein Smurf2 interacts with the Docking Protein NEDD9/HEF1 for Aurora A activation. Cell Division. 5: 22. PMID 20825672 DOI: 10.1186/1747-1028-5-22 |
0.697 |
|
2010 |
Adon AM, Zeng X, Harrison MK, Sannem S, Kiyokawa H, Kaldis P, Saavedra HI. Cdk2 and Cdk4 regulate the centrosome cycle and are critical mediators of centrosome amplification in p53-null cells. Molecular and Cellular Biology. 30: 694-710. PMID 19933848 DOI: 10.1128/Mcb.00253-09 |
0.535 |
|
2009 |
Osmundson EC, Ray D, Moore FE, Kiyokawa H. Smurf2 as a novel mitotic regulator: From the spindle assembly checkpoint to tumorigenesis. Cell Division. 4: 14. PMID 19583833 DOI: 10.1186/1747-1028-4-14 |
0.709 |
|
2008 |
Aronovitz A, Josefson J, Fisher A, Newman M, Hughes E, Chen F, Moons DS, Kiyokawa H, Lowe WL. Rapamycin inhibits growth factor-induced cell cycle regulation in pancreatic beta cells. Journal of Investigative Medicine : the Official Publication of the American Federation For Clinical Research. 56: 985-96. PMID 19105244 DOI: 10.2310/Jim.0B013E31818Ce763 |
0.466 |
|
2008 |
Kiyokawa H, Ray D. In vivo roles of CDC25 phosphatases: biological insight into the anti-cancer therapeutic targets. Anti-Cancer Agents in Medicinal Chemistry. 8: 832-6. PMID 19075565 DOI: 10.2174/187152008786847693 |
0.506 |
|
2008 |
Osmundson EC, Ray D, Moore FE, Gao Q, Thomsen GH, Kiyokawa H. The HECT E3 ligase Smurf2 is required for Mad2-dependent spindle assembly checkpoint. The Journal of Cell Biology. 183: 267-77. PMID 18852296 DOI: 10.1083/Jcb.200801049 |
0.709 |
|
2008 |
Gandin V, Miluzio A, Barbieri AM, Beugnet A, Kiyokawa H, Marchisio PC, Biffo S. Eukaryotic initiation factor 6 is rate-limiting in translation, growth and transformation. Nature. 455: 684-8. PMID 18784653 DOI: 10.1038/Nature07267 |
0.433 |
|
2008 |
Shehu A, Mao J, Gibori GB, Halperin J, Le J, Devi YS, Merrill B, Kiyokawa H, Gibori G. Prolactin receptor-associated protein/17beta-hydroxysteroid dehydrogenase type 7 gene (Hsd17b7) plays a crucial role in embryonic development and fetal survival. Molecular Endocrinology (Baltimore, Md.). 22: 2268-77. PMID 18669642 DOI: 10.1210/Me.2008-0165 |
0.403 |
|
2008 |
Ray D, Kiyokawa H. CDC25A phosphatase: a rate-limiting oncogene that determines genomic stability. Cancer Research. 68: 1251-3. PMID 18316586 DOI: 10.1158/0008-5472.Can-07-5983 |
0.471 |
|
2008 |
Liu L, Schwartz B, Tsubota Y, Raines E, Kiyokawa H, Yonekawa K, Harlan JM, Schnapp LM. Cyclin-dependent kinase inhibitors block leukocyte adhesion and migration. Journal of Immunology (Baltimore, Md. : 1950). 180: 1808-17. PMID 18209078 DOI: 10.4049/Jimmunol.180.3.1808 |
0.396 |
|
2007 |
Ray D, Kiyokawa H. CDC25A levels determine the balance of proliferation and checkpoint response. Cell Cycle (Georgetown, Tex.). 6: 3039-42. PMID 18073536 DOI: 10.4161/Cc.6.24.5104 |
0.476 |
|
2007 |
Ray D, Terao Y, Nimbalkar D, Hirai H, Osmundson EC, Zou X, Franks R, Christov K, Kiyokawa H. Hemizygous disruption of Cdc25A inhibits cellular transformation and mammary tumorigenesis in mice. Cancer Research. 67: 6605-11. PMID 17638870 DOI: 10.1158/0008-5472.Can-06-4815 |
0.742 |
|
2007 |
Cooke PS, Holsberger DR, Cimafranca MA, Meling DD, Beals CM, Nakayama K, Nakayama KI, Kiyokawa H. The F box protein S phase kinase-associated protein 2 regulates adipose mass and adipocyte number in vivo. Obesity (Silver Spring, Md.). 15: 1400-8. PMID 17557977 DOI: 10.1038/Oby.2007.168 |
0.435 |
|
2007 |
Luque RM, Amargo G, Ishii S, Lobe C, Franks R, Kiyokawa H, Kineman RD. Reporter expression, induced by a growth hormone promoter-driven Cre recombinase (rGHp-Cre) transgene, questions the developmental relationship between somatotropes and lactotropes in the adult mouse pituitary gland. Endocrinology. 148: 1946-53. PMID 17289844 DOI: 10.1210/En.2006-1542 |
0.457 |
|
2007 |
Ray D, Terao Y, Fuhrken PG, Ma ZQ, DeMayo FJ, Christov K, Heerema NA, Franks R, Tsai SY, Papoutsakis ET, Kiyokawa H. Deregulated CDC25A expression promotes mammary tumorigenesis with genomic instability. Cancer Research. 67: 984-91. PMID 17283130 DOI: 10.1158/0008-5472.Can-06-3927 |
0.474 |
|
2006 |
Rachdi L, Balcazar N, Elghazi L, Barker DJ, Krits I, Kiyokawa H, Bernal-Mizrachi E. Differential effects of p27 in regulation of beta-cell mass during development, neonatal period, and adult life. Diabetes. 55: 3520-8. PMID 17130500 DOI: 10.2337/Db06-0861 |
0.411 |
|
2006 |
Skeen JE, Bhaskar PT, Chen CC, Chen WS, Peng XD, Nogueira V, Hahn-Windgassen A, Kiyokawa H, Hay N. Akt deficiency impairs normal cell proliferation and suppresses oncogenesis in a p53-independent and mTORC1-dependent manner. Cancer Cell. 10: 269-80. PMID 17045205 DOI: 10.1016/J.Ccr.2006.08.022 |
0.504 |
|
2006 |
Kiyokawa H. Senescence and cell cycle control. Results and Problems in Cell Differentiation. 42: 257-70. PMID 16903214 DOI: 10.1007/400_001 |
0.419 |
|
2006 |
Ray D, Osmundson EC, Kiyokawa H. Constitutive and UV-induced fibronectin degradation is a ubiquitination-dependent process controlled by beta-TrCP. The Journal of Biological Chemistry. 281: 23060-5. PMID 16757476 DOI: 10.1074/Jbc.M604311200 |
0.668 |
|
2006 |
Sandoval R, Xue J, Tian X, Barrett K, Pilkinton M, Ucker DS, Raychaudhuri P, Kineman RD, Luque RM, Baida G, Zou X, Valli VE, Cook JL, Kiyokawa H, Colamonici OR. A mutant allele of BARA/LIN-9 rescues the cdk4-/- phenotype by releasing the repression on E2F-regulated genes. Experimental Cell Research. 312: 2465-75. PMID 16730350 DOI: 10.1016/J.Yexcr.2006.04.002 |
0.501 |
|
2006 |
Berthet C, Klarmann KD, Hilton MB, Suh HC, Keller JR, Kiyokawa H, Kaldis P. Combined loss of Cdk2 and Cdk4 results in embryonic lethality and Rb hypophosphorylation. Developmental Cell. 10: 563-73. PMID 16678773 DOI: 10.1016/J.Devcel.2006.03.004 |
0.472 |
|
2006 |
Fatrai S, Elghazi L, Balcazar N, Cras-Méneur C, Krits I, Kiyokawa H, Bernal-Mizrachi E. Akt induces beta-cell proliferation by regulating cyclin D1, cyclin D2, and p21 levels and cyclin-dependent kinase-4 activity. Diabetes. 55: 318-25. PMID 16443763 DOI: 10.2337/Diabetes.55.02.06.Db05-0757 |
0.476 |
|
2006 |
Yu Q, Sicinska E, Geng Y, Ahnström M, Zagozdzon A, Kong Y, Gardner H, Kiyokawa H, Harris LN, Stål O, Sicinski P. Requirement for CDK4 kinase function in breast cancer. Cancer Cell. 9: 23-32. PMID 16413469 DOI: 10.1016/J.Ccr.2005.12.012 |
0.358 |
|
2006 |
Kichina JV, Zeremski M, Aris L, Gurova KV, Walker E, Franks R, Nikitin AY, Kiyokawa H, Gudkov AV. Targeted disruption of the mouse ing1 locus results in reduced body size, hypersensitivity to radiation and elevated incidence of lymphomas Oncogene. 25: 857-866. PMID 16170338 DOI: 10.1038/Sj.Onc.1209118 |
0.438 |
|
2005 |
Abella A, Dubus P, Malumbres M, Rane SG, Kiyokawa H, Sicard A, Vignon F, Langin D, Barbacid M, Fajas L. Cdk4 promotes adipogenesis through PPARgamma activation. Cell Metabolism. 2: 239-49. PMID 16213226 DOI: 10.1016/J.Cmet.2005.09.003 |
0.515 |
|
2005 |
Mukai M, Dong Q, Hardy MP, Kiyokawa H, Peterson RE, Cooke PS. Altered prostatic epithelial proliferation and apoptosis, prostatic development, and serum testosterone in mice lacking cyclin-dependent kinase inhibitors. Biology of Reproduction. 73: 951-8. PMID 16014817 DOI: 10.1095/Biolreprod.105.040980 |
0.376 |
|
2005 |
Aleem E, Kiyokawa H, Kaldis P. Cdc2-cyclin E complexes regulate the G1/S phase transition. Nature Cell Biology. 7: 831-6. PMID 16007079 DOI: 10.1038/Ncb1284 |
0.502 |
|
2005 |
Ray D, Terao Y, Nimbalkar D, Chu LH, Donzelli M, Tsutsui T, Zou X, Ghosh AK, Varga J, Draetta GF, Kiyokawa H. Transforming growth factor beta facilitates beta-TrCP-mediated degradation of Cdc25A in a Smad3-dependent manner. Molecular and Cellular Biology. 25: 3338-47. PMID 15798217 DOI: 10.1128/Mcb.25.8.3338-3347.2005 |
0.342 |
|
2005 |
Holsberger DR, Buchold GM, Leal MC, Kiesewetter SE, O'Brien DA, Hess RA, França LR, Kiyokawa H, Cooke PS. Cell-cycle inhibitors p27Kip1 and p21Cip1 regulate murine Sertoli cell proliferation. Biology of Reproduction. 72: 1429-36. PMID 15728790 DOI: 10.1095/Biolreprod.105.040386 |
0.535 |
|
2005 |
Yoon T, Chakrabortty A, Franks R, Valli T, Kiyokawa H, Raychaudhuri P. Tumor-prone phenotype of the DDB2-deficient mice. Oncogene. 24: 469-78. PMID 15558025 DOI: 10.1038/Sj.Onc.1208211 |
0.439 |
|
2004 |
Krupczak-Hollis K, Wang X, Kalinichenko VV, Gusarova GA, Wang IC, Dennewitz MB, Yoder HM, Kiyokawa H, Kaestner KH, Costa RH. The mouse Forkhead Box m1 transcription factor is essential for hepatoblast mitosis and development of intrahepatic bile ducts and vessels during liver morphogenesis. Developmental Biology. 276: 74-88. PMID 15531365 DOI: 10.1016/J.Ydbio.2004.08.022 |
0.376 |
|
2004 |
Naaz A, Holsberger DR, Iwamoto GA, Nelson A, Kiyokawa H, Cooke PS. Loss of cyclin-dependent kinase inhibitors produces adipocyte hyperplasia and obesity. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 18: 1925-7. PMID 15469964 DOI: 10.1096/Fj.04-2631Fje |
0.449 |
|
2004 |
Jirawatnotai S, Aziyu A, Osmundson EC, Moons DS, Zou X, Kineman RD, Kiyokawa H. Cdk4 is indispensable for postnatal proliferation of the anterior pituitary. The Journal of Biological Chemistry. 279: 51100-6. PMID 15456744 DOI: 10.1074/Jbc.M409080200 |
0.779 |
|
2004 |
Miliani de Marval PL, Macias E, Rounbehler R, Sicinski P, Kiyokawa H, Johnson DG, Conti CJ, Rodriguez-Puebla ML. Lack of cyclin-dependent kinase 4 inhibits c-myc tumorigenic activities in epithelial tissues. Molecular and Cellular Biology. 24: 7538-47. PMID 15314163 DOI: 10.1128/Mcb.24.17.7538-7547.2004 |
0.46 |
|
2004 |
Pei XH, Bai F, Tsutsui T, Kiyokawa H, Xiong Y. Genetic evidence for functional dependency of p18Ink4c on Cdk4. Molecular and Cellular Biology. 24: 6653-64. PMID 15254233 DOI: 10.1128/Mcb.24.15.6653-6664.2004 |
0.499 |
|
2004 |
Sandoval R, Xue J, Pilkinton M, Salvi D, Kiyokawa H, Colamonici OR. Different requirements for the cytostatic and apoptotic effects of type I interferons. Induction of apoptosis requires ARF but not p53 in osteosarcoma cell lines. The Journal of Biological Chemistry. 279: 32275-80. PMID 15169789 DOI: 10.1074/Jbc.M313830200 |
0.447 |
|
2004 |
Srivastava KK, Batra S, Sassano A, Li Y, Majchrzak B, Kiyokawa H, Altman A, Fish EN, Platanias LC. Engagement of protein kinase C-theta in interferon signaling in T-cells. The Journal of Biological Chemistry. 279: 29911-20. PMID 15150272 DOI: 10.1074/Jbc.M401997200 |
0.426 |
|
2003 |
Holsberger DR, Jirawatnotai S, Kiyokawa H, Cooke PS. Thyroid hormone regulates the cell cycle inhibitor p27Kip1 in postnatal murine Sertoli cells. Endocrinology. 144: 3732-8. PMID 12933641 DOI: 10.1210/En.2003-0389 |
0.748 |
|
2003 |
Jirawatnotai S, Moons DS, Stocco CO, Franks R, Hales DB, Gibori G, Kiyokawa H. The cyclin-dependent kinase inhibitors p27Kip1 and p21Cip1 cooperate to restrict proliferative life span in differentiating ovarian cells. The Journal of Biological Chemistry. 278: 17021-7. PMID 12609976 DOI: 10.1074/Jbc.M301206200 |
0.741 |
|
2002 |
Wang X, Kiyokawa H, Dennewitz MB, Costa RH. The Forkhead Box m1b transcription factor is essential for hepatocyte DNA replication and mitosis during mouse liver regeneration. Proceedings of the National Academy of Sciences of the United States of America. 99: 16881-6. PMID 12482952 DOI: 10.1073/Pnas.252570299 |
0.458 |
|
2002 |
Zou X, Ray D, Aziyu A, Christov K, Boiko AD, Gudkov AV, Kiyokawa H. Cdk4 disruption renders primary mouse cells resistant to oncogenic transformation, leading to Arf/p53-independent senescence. Genes & Development. 16: 2923-34. PMID 12435633 DOI: 10.1101/Gad.1033002 |
0.532 |
|
2002 |
Kwon YH, Jovanovic A, Serfas MS, Kiyokawa H, Tyner AL. P21 functions to maintain quiescence of p27-deficient hepatocytes. The Journal of Biological Chemistry. 277: 41417-22. PMID 12202477 DOI: 10.1074/Jbc.M203388200 |
0.423 |
|
2002 |
Rodriguez-Puebla ML, Miliani de Marval PL, LaCava M, Moons DS, Kiyokawa H, Conti CJ. Cdk4 deficiency inhibits skin tumor development but does not affect normal keratinocyte proliferation. The American Journal of Pathology. 161: 405-11. PMID 12163365 DOI: 10.1016/S0002-9440(10)64196-X |
0.424 |
|
2002 |
Moons DS, Jirawatnotai S, Parlow AF, Gibori G, Kineman RD, Kiyokawa H. Pituitary hypoplasia and lactotroph dysfunction in mice deficient for cyclin-dependent kinase-4. Endocrinology. 143: 3001-8. PMID 12130566 DOI: 10.1210/Endo.143.8.8956 |
0.731 |
|
2002 |
Moons DS, Jirawatnotai S, Tsutsui T, Franks R, Parlow AF, Hales DB, Gibori G, Fazleabas AT, Kiyokawa H. Intact follicular maturation and defective luteal function in mice deficient for cyclin- dependent kinase-4. Endocrinology. 143: 647-54. PMID 11796521 DOI: 10.1210/Endo.143.2.8611 |
0.763 |
|
2001 |
Miyazaki Y, Boccuni P, Mao S, Zhang J, Erdjument-Bromage H, Tempst P, Kiyokawa H, Nimer SD. Cyclin A-dependent phosphorylation of the ETS-related protein, MEF, restricts its activity to the G1 phase of the cell cycle. The Journal of Biological Chemistry. 276: 40528-36. PMID 11504716 DOI: 10.1074/JBC.M103051200 |
0.39 |
|
2001 |
Zou X, Tsutsui T, Ray D, Blomquist JF, Ichijo H, Ucker DS, Kiyokawa H. The cell cycle-regulatory CDC25a phosphatase inhibits apoptosis signal-regulating kinase 1 Molecular and Cellular Biology. 21: 4818-4828. PMID 11416155 DOI: 10.1128/Mcb.21.14.4818-4828.2001 |
0.482 |
|
2000 |
Teixeira LT, Kiyokawa H, Peng XD, Christov KT, Frohman LA, Kineman RD. p27Kip1-deficient mice exhibit accelerated growth hormone-releasing hormone (GHRH)-induced somatotrope proliferation and adenoma formation. Oncogene. 19: 1875-84. PMID 10773877 DOI: 10.1038/Sj.Onc.1203490 |
0.439 |
|
2000 |
Tsutsui T, Hesabi B, Moons DS, Pandolfi PP, Hansel KS, Koff A, Kiyokawa H. Targeted disruption of CDK4 delays cell cycle entry with enhanced p27(Kip1) activity. Molecular and Cellular Biology. 19: 7011-9. PMID 10490638 DOI: 10.1128/Mcb.19.10.7011 |
0.559 |
|
2000 |
Tyner AL, Kwon YH, Kiyokawa H, Serfas MS. Differential regulation of the CDK inhibitor p27 (KIP1) following CCL4 induced liver injury Gastroenterology. 118: A921. DOI: 10.1016/S0016-5085(00)85821-7 |
0.336 |
|
1999 |
Beumer TL, Kiyokawa H, Roepers-Gajadien HL, van den Bos LA, Lock TM, Gademan IS, Rutgers DH, Koff A, de Rooij DG. Regulatory role of p27kip1 in the mouse and human testis. Endocrinology. 140: 1834-40. PMID 10098522 DOI: 10.1210/Endo.140.4.6638 |
0.515 |
|
1998 |
Soos TJ, Park M, Kiyokawa H, Koff A. Regulation of the cell cycle by CDK inhibitors. Results and Problems in Cell Differentiation. 22: 111-31. PMID 9670321 DOI: 10.1007/978-3-540-69686-5_5 |
0.398 |
|
1997 |
Kiyokawa H, Koff A. Roles of cyclin-dependent kinase inhibitors: Lessons from knockout mice Current Topics in Microbiology and Immunology. 227: 105-120. PMID 9479827 |
0.341 |
|
1997 |
Langenfeld J, Kiyokawa H, Sekula D, Boyle J, Dmitrovsky E. Posttranslational regulation of cyclin D1 by retinoic acid: a chemoprevention mechanism. Proceedings of the National Academy of Sciences of the United States of America. 94: 12070-4. PMID 9342364 DOI: 10.1073/Pnas.94.22.12070 |
0.308 |
|
1997 |
Casaccia-Bonnefil P, Tikoo R, Kiyokawa H, Friedrich V, Chao MV, Koff A. Oligodendrocyte precursor differentiation is perturbed in the absence of the cyclin-dependent kinase inhibitor p27Kip1. Genes & Development. 11: 2335-46. PMID 9308962 DOI: 10.1101/Gad.11.18.2335 |
0.401 |
|
1997 |
Millard SS, Yan JS, Nguyen H, Pagano M, Kiyokawa H, Koff A. Enhanced ribosomal association of p27(Kip1) mRNA is a mechanism contributing to accumulation during growth arrest. The Journal of Biological Chemistry. 272: 7093-8. PMID 9054402 DOI: 10.1074/Jbc.272.11.7093 |
0.366 |
|
1997 |
Luo Y, Marx SO, Kiyokawa H, Koff A, Massagué J, Marks AR. Rapamycin resistance tied to defective regulation of p27Kip1. Molecular and Cellular Biology. 16: 6744-51. PMID 8943329 DOI: 10.1128/Mcb.16.12.6744 |
0.376 |
|
1996 |
Missero C, Di Cunto F, Kiyokawa H, Koff A, Dotto GP. The absence of p21(Cip1/WAF1) alters keratinocyte growth and differentiation and promotes ras-tumor progression Genes and Development. 10: 3065-3075. PMID 8957006 |
0.346 |
|
1996 |
Kiyokawa H, Kineman RD, Manova-Todorova KO, Soares VC, Hoffman ES, Ono M, Khanam D, Hayday AC, Frohman LA, Koff A. Enhanced growth of mice lacking the cyclin-dependent kinase inhibitor function of p27(Kip1). Cell. 85: 721-32. PMID 8646780 DOI: 10.1016/S0092-8674(00)81238-6 |
0.43 |
|
1994 |
Marks PA, Richon VM, Kiyokawa H, Rifkind RA. Inducing differentiation of transformed cells with hybrid polar compounds: a cell cycle-dependent process. Proceedings of the National Academy of Sciences of the United States of America. 91: 10251-4. PMID 7937935 DOI: 10.1073/pnas.91.22.10251 |
0.338 |
|
1994 |
Kiyokawa H, Richon VM, Rifkind RA, Marks PA. Suppression of cyclin-dependent kinase 4 during induced differentiation of erythroleukemia cells. Molecular and Cellular Biology. 14: 7195-203. PMID 7935434 DOI: 10.1128/MCB.14.11.7195 |
0.407 |
|
1993 |
Kiyokawa H, Richon VM, Venta-Perez G, Rifkind RA, Marks PA. Hexamethylenebisacetamide-induced erythroleukemia cell differentiation involves modulation of events required for cell cycle progression through G1. Proceedings of the National Academy of Sciences of the United States of America. 90: 6746-50. PMID 8341693 DOI: 10.1073/pnas.90.14.6746 |
0.336 |
|
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