Lynda F. Bonewald - Publications

Affiliations: 
University of Missouri - Kansas City, USA 
Area:
Cell Biology

203 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Shimonty A, Pin F, Prideaux M, Peng G, Huot J, Kim H, Rosen CJ, Spiegelman BM, Bonewald LF. Deletion of FNDC5/irisin modifies murine osteocyte function in a sex-specific manner. Elife. 12. PMID 38661340 DOI: 10.7554/eLife.92263  0.328
2023 Shimonty A, Pin F, Prideaux M, Peng G, Huot JR, Kim H, Rosen CJ, Spiegelman BM, Bonewald LF. Deletion of FNDC5/Irisin modifies murine osteocyte function in a sex-specific manner. Biorxiv : the Preprint Server For Biology. PMID 37986762 DOI: 10.1101/2023.11.06.565774  0.328
2023 Shimonty A, Bonewald LF, Huot JR. Metabolic Health and Disease: A Role of Osteokines? Calcified Tissue International. PMID 37193929 DOI: 10.1007/s00223-023-01093-0  0.302
2023 Williams JN, Irwin M, Li Y, Kambrath AV, Mattingly BT, Patel S, Kittaka M, Collins RN, Clough NA, Doud EH, Mosley AL, Bellido T, Bruzzaniti A, Plotkin LI, Trinidad JC, ... ... Bonewald LF, et al. Osteocyte-Derived CaMKK2 Regulates Osteoclasts and Bone Mass in a Sex-Dependent Manner through Secreted Calpastatin. International Journal of Molecular Sciences. 24. PMID 36902150 DOI: 10.3390/ijms24054718  0.381
2022 Yoshimoto T, Kittaka M, Doan AAP, Urata R, Prideaux M, Rojas RE, Harding CV, Henry Boom W, Bonewald LF, Greenfield EM, Ueki Y. Osteocytes directly regulate osteolysis via MYD88 signaling in bacterial bone infection. Nature Communications. 13: 6648. PMID 36333322 DOI: 10.1038/s41467-022-34352-z  0.388
2021 Pin F, Jones AJ, Huot JR, Narasimhan A, Zimmers TA, Bonewald LF, Bonetto A. RANKL Blockade Reduces Cachexia and Bone Loss Induced by Non-Metastatic Ovarian Cancer in Mice. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 34904285 DOI: 10.1002/jbmr.4480  0.377
2021 Toda Nakamura M, Zhang H, Guo D, Ueharu H, Pan H, Scott G, Harris M, Ray M, Feng JQ, Harris SE, Bonewald LF, Mishina Y. Podoplanin is dispensable for mineralized tissue formation and maintenance in the Swiss outbred mouse background. Genesis (New York, N.Y. : 2000). e23450. PMID 34487426 DOI: 10.1002/dvg.23450  0.711
2021 Pin F, Prideaux M, Huot JR, Essex AL, Plotkin LI, Bonetto A, Bonewald LF. Non-bone metastatic cancers promote osteocyte-induced bone destruction. Cancer Letters. PMID 34233150 DOI: 10.1016/j.canlet.2021.06.030  0.375
2021 Prideaux M, Stern AR, Bonewald LF. Isolation of Murine and Human Osteocytes. Methods in Molecular Biology (Clifton, N.J.). 2221: 3-13. PMID 32979194 DOI: 10.1007/978-1-0716-0989-7_1  0.41
2020 Prideaux M, Kitase Y, Kimble M, O'Connell TM, Bonewald LF. Taurine, an osteocyte metabolite, protects against oxidative stress-induced cell death and decreases inhibitors of the Wnt/β-catenin signaling pathway. Bone. 137: 115374. PMID 32330695 DOI: 10.1016/J.Bone.2020.115374  0.456
2020 Robling AG, Bonewald LF. The Osteocyte: New Insights. Annual Review of Physiology. 82: 485-506. PMID 32040934 DOI: 10.1146/Annurev-Physiol-021119-034332  0.518
2020 Wang H, Li T, Wang X, Yin X, Zhao N, Zou S, Duan P, Bonewald LF. The role of sphingosine-1-phosphate signaling pathway in cementocyte mechanotransduction. Biochemical and Biophysical Research Communications. PMID 31941604 DOI: 10.1016/J.Bbrc.2020.01.003  0.424
2019 Essex AL, Pin F, Huot JR, Bonewald LF, Plotkin LI, Bonetto A. Bisphosphonate Treatment Ameliorates Chemotherapy-Induced Bone and Muscle Abnormalities in Young Mice. Frontiers in Endocrinology. 10: 809. PMID 31803146 DOI: 10.3389/Fendo.2019.00809  0.454
2019 Pacicca DM, Brown T, Watkins D, Kover K, Yan Y, Prideaux M, Bonewald L. Elevated glucose acts directly on osteocytes to increase sclerostin expression in diabetes. Scientific Reports. 9: 17353. PMID 31757981 DOI: 10.1038/S41598-019-52224-3  0.39
2019 Huang J, Wang K, Shiflett LA, Brotto L, Bonewald LF, Wacker MJ, Dallas SL, Brotto M. Fibroblast growth factor 9 (FGF9) inhibits myogenic differentiation of C2C12 and human muscle cells. Cell Cycle (Georgetown, Tex.). 1-19. PMID 31735119 DOI: 10.1080/15384101.2019.1691796  0.394
2019 Mo C, Wang Z, Bonewald L, Brotto M. Multi-Staged Regulation of Lipid Signaling Mediators during Myogenesis by COX-1/2 Pathways. International Journal of Molecular Sciences. 20. PMID 31487817 DOI: 10.3390/Ijms20184326  0.31
2019 Pin F, Bonetto A, Bonewald LF, Klein GL. Molecular Mechanisms Responsible for the Rescue Effects of Pamidronate on Muscle Atrophy in Pediatric Burn Patients. Frontiers in Endocrinology. 10: 543. PMID 31447786 DOI: 10.3389/Fendo.2019.00543  0.302
2019 Kim H, Wrann CD, Jedrychowski M, Vidoni S, Kitase Y, Nagano K, Zhou C, Chou J, Parkman VA, Novick SJ, Strutzenberg TS, Pascal BD, Le PT, Brooks DJ, Roche AM, ... ... Bonewald LF, et al. Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors. Cell. 178: 507-508. PMID 31299203 DOI: 10.1016/J.Cell.2019.06.028  0.43
2019 Wang K, Le L, Chun BM, Tiede-Lewis LAM, Shiflett LA, Prideaux M, Campos RS, Veno PA, Xie Y, Dusevich V, Bonewald LF, Dallas SL. A Novel Osteogenic Cell Line that Differentiates into GFP-Tagged Osteocytes and forms Mineral with a Bone-like Lacunocanalicular Structure. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 30882939 DOI: 10.1002/Jbmr.3720  0.549
2019 Maurel DB, Matsumoto T, Vallejo JA, Johnson ML, Dallas SL, Kitase Y, Brotto M, Wacker MJ, Harris MA, Harris SE, Bonewald LF. Characterization of a novel murine Sost ER Cre model targeting osteocytes. Bone Research. 7: 6. PMID 30820362 DOI: 10.1038/S41413-018-0037-4  0.458
2019 Bonewald L. Use It or Lose It to Age: A Review of Bone and Muscle Communication Bone. 120: 212-218. PMID 30408611 DOI: 10.1016/J.Bone.2018.11.002  0.417
2018 Kim H, Wrann CD, Jedrychowski M, Vidoni S, Kitase Y, Nagano K, Zhou C, Chou J, Parkman VA, Novick SJ, Strutzenberg TS, Pascal BD, Le PT, Brooks DJ, Roche AM, ... ... Bonewald LF, et al. Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors. Cell. 175: 1756-1768.e17. PMID 30550785 DOI: 10.1016/J.Cell.2018.10.025  0.446
2018 Tsourdi E, Jähn K, Rauner M, Busse B, Bonewald LF. Physiological and pathological osteocytic osteolysis. Journal of Musculoskeletal & Neuronal Interactions. 18: 292-303. PMID 30179206  0.368
2018 Colditz J, Thiele S, Baschant U, Niehrs C, Bonewald LF, Hofbauer LC, Rauner M. Postnatal skeletal deletion of Dickkopf-1 increases bone formation and bone volume in male and female mice, despite increased sclerostin expression. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 29734465 DOI: 10.1002/Jbmr.3463  0.538
2018 Morrell AE, Brown GN, Robinson ST, Sattler RL, Baik AD, Zhen G, Cao X, Bonewald LF, Jin W, Kam LC, Guo XE. Mechanically induced Caoscillations in osteocytes release extracellular vesicles and enhance bone formation. Bone Research. 6: 6. PMID 29581909 DOI: 10.1038/S41413-018-0007-X  0.48
2018 Yajima A, Tsuchiya K, Bonewald LF, Inaba M, Tominaga Y, Tanizawa T, Ito A, Nitta K. Case report: Electron microscopic evaluation of bone from a patient treated with cinacalcet hydrochloride, maxacalcitol, and alfacalcidol for hyperparathyroid bone disease with secondary hyperparathyroidism. Osteoporosis International : a Journal Established as Result of Cooperation Between the European Foundation For Osteoporosis and the National Osteoporosis Foundation of the Usa. PMID 29492624 DOI: 10.1007/S00198-018-4402-3  0.467
2018 Lu Y, Sayed SAK, Wang K, Tiede-Lewis LM, Grillo MA, Veno PA, Dusevich V, Phillips CL, Bonewald LF, Dallas SL. Live Imaging of Type I Collagen Assembly Dynamics in Osteoblasts Stably Expressing GFP and mCherry-tagged Collagen Constructs. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 29461659 DOI: 10.1002/Jbmr.3409  0.381
2018 Kitase Y, Vallejo JA, Gutheil W, Vemula H, Jähn K, Yi J, Zhou J, Brotto M, Bonewald LF. β-aminoisobutyric Acid, l-BAIBA, Is a Muscle-Derived Osteocyte Survival Factor. Cell Reports. 22: 1531-1544. PMID 29425508 DOI: 10.1016/J.Celrep.2018.01.041  0.38
2018 Ward LM, Kinnett K, Bonewald L. Proceedings of a Parent Project Muscular Dystrophy Bone Health Workshop: Morbidity due to osteoporosis in DMD: The Path Forward May 12-13, 2016, Bethesda, Maryland, USA. Neuromuscular Disorders : Nmd. 28: 64-76. PMID 28756052 DOI: 10.1016/J.Nmd.2017.05.012  0.358
2017 Barreto R, Kitase Y, Matsumoto T, Pin F, Colston KC, Couch KE, O'Connell TM, Couch ME, Bonewald LF, Bonetto A. ACVR2B/Fc counteracts chemotherapy-induced loss of muscle and bone mass. Scientific Reports. 7: 14470. PMID 29089584 DOI: 10.1038/S41598-017-15040-1  0.456
2017 Tiede-Lewis LM, Xie Y, Hulbert MA, Campos R, Dallas MR, Dusevich V, Bonewald LF, Dallas SL. Degeneration of the osteocyte network in the C57BL/6 mouse model of aging. Aging. PMID 29074822 DOI: 10.18632/aging.101308  0.357
2017 Medina-Gomez C, Kemp JP, Dimou NL, Kreiner E, Chesi A, Zemel BS, Bønnelykke K, Boer CG, Ahluwalia TS, Bisgaard H, Evangelou E, Heppe DHM, Bonewald LF, Gorski JP, Ghanbari M, et al. Bivariate genome-wide association meta-analysis of pediatric musculoskeletal traits reveals pleiotropic effects at the SREBF1/TOM1L2 locus. Nature Communications. 8: 121. PMID 28743860 DOI: 10.1038/S41467-017-00108-3  0.402
2017 Jähn K, Kelkar S, Zhao H, Xie Y, Tiede-Lewis LM, Dusevich V, Dallas SL, Bonewald LF. Osteocytes Acidify their Microenvironment in response to PTHrP in vitro and in Lactating Mice in vivo. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 28470757 DOI: 10.1002/Jbmr.3167  0.419
2017 Qin Y, Peng Y, Zhao W, Pan J, Ksiezak-Reding H, Cardozo C, Wu Y, Divieti Pajevic P, Bonewald LF, Bauman WA, Qin W. Myostatin Inhibits Osteoblastic Differentiation by Suppressing Osteocyte-derived Exosomal microRNA-218: A Novel Mechanism in Muscle-Bone Communication. The Journal of Biological Chemistry. PMID 28465350 DOI: 10.1074/Jbc.M116.770941  0.457
2017 Bonewald LF. The Role of the Osteocyte in Bone and Nonbone Disease. Endocrinology and Metabolism Clinics of North America. 46: 1-18. PMID 28131126 DOI: 10.1016/j.ecl.2016.09.003  0.385
2016 Montesi M, Jähn K, Bonewald L, Stea S, Bordini B, Beraudi A. Hypoxia mediates osteocyte ORP150 expression and cell death in vitro. Molecular Medicine Reports. 14: 4248-4254. PMID 27748851 DOI: 10.3892/Mmr.2016.5790  0.471
2016 Maurel DB, Duan P, Farr J, Cheng AL, Johnson ML, Bonewald LF. Beta-Catenin Haplo Insufficient Male Mice Do Not Lose Bone in Response to Hindlimb Unloading. Plos One. 11: e0158381. PMID 27410430 DOI: 10.1371/Journal.Pone.0158381  0.357
2016 Farr JN, Fraser DG, Wang H, Jaehn K, Ogrodnik MB, Weivoda MM, Drake MT, Tchkonia T, LeBrasseur NK, Kirkland JL, Bonewald LF, Pignolo RJ, Monroe DG, Khosla S. Identification of Senescent Cells in the Bone Microenvironment. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 27341653 DOI: 10.1002/Jbmr.2892  0.49
2016 Duan P, Bonewald LF. The Role of the Wnt/β-catenin Signaling Pathway in Formation and Maintenance of Bone and Teeth. The International Journal of Biochemistry & Cell Biology. PMID 27210503 DOI: 10.1016/J.Biocel.2016.05.015  0.338
2016 Zhao N, Foster BL, Bonewald LF. The Cementocyte-An Osteocyte Relative? Journal of Dental Research. PMID 27029548 DOI: 10.1177/0022034516641898  0.369
2016 Yamamoto H, Ramos-Molina B, Lick AN, Prideaux M, Albornoz V, Bonewald L, Lindberg I. Posttranslational processing of FGF23 in osteocytes during the osteoblast to osteocyte transition. Bone. 84: 120-30. PMID 26746780 DOI: 10.1016/J.Bone.2015.12.055  0.393
2016 Thiele S, Baschant U, Thiele S, Niehrs C, Bonewald L, Hofbauer LC, Rauner M. Deletion of Dickkopf-1 in osteoblasts or osteocytes increases bone volume in female mice Bone Abstracts. DOI: 10.1530/Boneabs.5.Oc2.2  0.453
2016 Lin Y, Xiao W, Liu X, Bal BS, Bonewald LF, Rahaman MN. Long-term bone regeneration, mineralization and angiogenesis in rat calvarial defects implanted with strong porous bioactive glass (13-93) scaffolds Journal of Non-Crystalline Solids. 432: 120-129. DOI: 10.1016/J.Jnoncrysol.2015.04.008  0.448
2015 Gorski JP, Huffman NT, Vallejo J, Brotto L, Chittur SV, Breggia A, Stern A, Huang J, Mo C, Seidah NG, Bonewald L, Brotto M. Deletion of Mbtps1 (PCSK8, S1P, SKI-1) in Osteocytes Stimulates Soleus Muscle Regeneration and Increased Size and Contractile Force with Age. The Journal of Biological Chemistry. PMID 26719336 DOI: 10.1074/Jbc.M115.686626  0.393
2015 Brotto M, Bonewald L. Bone and muscle: Interactions beyond mechanical Bone. 80: 109-114. PMID 26453500 DOI: 10.1016/J.Bone.2015.02.010  0.419
2015 Xiong J, Piemontese M, Onal M, Campbell J, Goellner JJ, Dusevich V, Bonewald L, Manolagas SC, O'Brien CA. Osteocytes, not Osteoblasts or Lining Cells, are the Main Source of the RANKL Required for Osteoclast Formation in Remodeling Bone. Plos One. 10: e0138189. PMID 26393791 DOI: 10.1371/Journal.Pone.0138189  0.535
2015 Zhao N, Nociti FH, Duan P, Prideaux M, Zhao H, Foster BL, Somerman MJ, Bonewald LF. Isolation and Functional Analysis of an Immortalized Murine Cementocyte Cell Line, IDG-CM6. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 26274352 DOI: 10.1002/Jbmr.2690  0.477
2015 Zhou J, Yi J, Bonewald L. Muscle-Bone Crosstalk in Amyotrophic Lateral Sclerosis. Current Osteoporosis Reports. 13: 274-9. PMID 26223903 DOI: 10.1007/S11914-015-0281-0  0.398
2015 Prideaux M, Dallas SL, Zhao N, Johnsrud ED, Veno PA, Guo D, Mishina Y, Harris SE, Bonewald LF. Parathyroid Hormone Induces Bone Cell Motility and Loss of Mature Osteocyte Phenotype through L-Calcium Channel Dependent and Independent Mechanisms. Plos One. 10: e0125731. PMID 25942444 DOI: 10.1371/Journal.Pone.0125731  0.74
2015 Mo C, Zhao R, Vallejo J, Igwe O, Bonewald L, Wetmore L, Brotto M. Prostaglandin E2 promotes proliferation of skeletal muscle myoblasts via EP4 receptor activation. Cell Cycle (Georgetown, Tex.). 14: 1507-16. PMID 25785867 DOI: 10.1080/15384101.2015.1026520  0.356
2015 Bonewald LF. Does defective bone lead to defective muscle? Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 30: 593-5. PMID 25727709 DOI: 10.1002/Jbmr.2491  0.389
2015 St John HC, Meyer MB, Benkusky NA, Carlson AH, Prideaux M, Bonewald LF, Pike JW. The parathyroid hormone-regulated transcriptome in osteocytes: parallel actions with 1,25-dihydroxyvitamin D3 to oppose gene expression changes during differentiation and to promote mature cell function. Bone. 72: 81-91. PMID 25460572 DOI: 10.1016/J.Bone.2014.11.010  0.388
2015 Ito N, Wijenayaka AR, Prideaux M, Kogawa M, Ormsby RT, Evdokiou A, Bonewald LF, Findlay DM, Atkins GJ. Regulation of FGF23 expression in IDG-SW3 osteocytes and human bone by pro-inflammatory stimuli. Molecular and Cellular Endocrinology. 399: 208-18. PMID 25458698 DOI: 10.1016/J.Mce.2014.10.007  0.353
2015 Dennis SC, Berkland CJ, Bonewald LF, Detamore MS. Endochondral ossification for enhancing bone regeneration: converging native extracellular matrix biomaterials and developmental engineering in vivo. Tissue Engineering. Part B, Reviews. 21: 247-66. PMID 25336144 DOI: 10.1089/Ten.Teb.2014.0419  0.482
2015 Stern AR, Bonewald LF. Isolation of osteocytes from mature and aged murine bone. Methods in Molecular Biology (Clifton, N.J.). 1226: 3-10. PMID 25331038 DOI: 10.1007/978-1-4939-1619-1_1  0.508
2015 Xu H, Gu S, Riquelme MA, Burra S, Callaway D, Cheng H, Guda T, Schmitz J, Fajardo RJ, Werner SL, Zhao H, Shang P, Johnson ML, Bonewald LF, Jiang JX. Connexin 43 channels are essential for normal bone structure and osteocyte viability. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 30: 436-48. PMID 25270829 DOI: 10.1002/Jbmr.2374  0.513
2015 Lindberg I, Pang HW, Stains JP, Clark D, Yang AJ, Bonewald L, Li KZ. FGF23 is endogenously phosphorylated in bone cells. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 30: 449-54. PMID 25195776 DOI: 10.1002/Jbmr.2354  0.443
2014 Kitase Y, Lee S, Gluhak-Heinrich J, Johnson ML, Harris SE, Bonewald LF. CCL7 is a protective factor secreted by mechanically loaded osteocytes. Journal of Dental Research. 93: 1108-15. PMID 25274752 DOI: 10.1177/0022034514553008  0.35
2014 Bi L, Zobell B, Liu X, Rahaman MN, Bonewald LF. Healing of critical-size segmental defects in rat femora using strong porous bioactive glass scaffolds. Materials Science & Engineering. C, Materials For Biological Applications. 42: 816-24. PMID 25063184 DOI: 10.1016/J.Msec.2014.06.022  0.39
2014 Rios HF, Bonewald LF, Conway SJ. Lessons from the matricellular factor periostin. Journal of Dental Research. 93: 843-5. PMID 25012809 DOI: 10.1177/0022034514543017  0.35
2014 St John HC, Bishop KA, Meyer MB, Benkusky NA, Leng N, Kendziorski C, Bonewald LF, Pike JW. The osteoblast to osteocyte transition: epigenetic changes and response to the vitamin D3 hormone. Molecular Endocrinology (Baltimore, Md.). 28: 1150-65. PMID 24877565 DOI: 10.1210/Me.2014-1091  0.363
2014 Huang J, Hsu YH, Mo C, Abreu E, Kiel DP, Bonewald LF, Brotto M, Karasik D. METTL21C is a potential pleiotropic gene for osteoporosis and sarcopenia acting through the modulation of the NF-κB signaling pathway. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 29: 1531-40. PMID 24677265 DOI: 10.1002/Jbmr.2200  0.447
2014 Lewiecki EM, Bilezikian JP, Bonewald L, Compston JE, Heaney RP, Kiel DP, Miller PD, Schousboe JT. Osteoporosis update: proceedings of the 2013 Santa Fe Bone Symposium. Journal of Clinical Densitometry : the Official Journal of the International Society For Clinical Densitometry. 17: 330-43. PMID 24613387 DOI: 10.1016/J.Jocd.2013.11.006  0.44
2014 Kondoh S, Inoue K, Igarashi K, Sugizaki H, Shirode-Fukuda Y, Inoue E, Yu T, Takeuchi JK, Kanno J, Bonewald LF, Imai Y. Estrogen receptor α in osteocytes regulates trabecular bone formation in female mice. Bone. 60: 68-77. PMID 24333171 DOI: 10.1016/J.Bone.2013.12.005  0.511
2014 Javaheri B, Stern AR, Lara N, Dallas M, Zhao H, Liu Y, Bonewald LF, Johnson ML. Deletion of a single β-catenin allele in osteocytes abolishes the bone anabolic response to loading. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 29: 705-15. PMID 23929793 DOI: 10.1002/Jbmr.2064  0.441
2014 Klein GL, Xie Y, Qin YX, Lin L, Hu M, Enkhbaatar P, Bonewald LF. Preliminary evidence of early bone resorption in a sheep model of acute burn injury: an observational study. Journal of Bone and Mineral Metabolism. 32: 136-41. PMID 23784552 DOI: 10.1007/S00774-013-0483-4  0.43
2014 Jilka RL, O'Brien CA, Roberson PK, Bonewald LF, Weinstein RS, Manolagas SC. Dysapoptosis of osteoblasts and osteocytes increases cancellous bone formation but exaggerates cortical porosity with age Journal of Bone and Mineral Research. 29: 103-117. PMID 23761243 DOI: 10.1002/Jbmr.2007  0.491
2013 Kogawa M, Wijenayaka AR, Ormsby RT, Thomas GP, Anderson PH, Bonewald LF, Findlay DM, Atkins GJ. Sclerostin regulates release of bone mineral by osteocytes by induction of carbonic anhydrase 2. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 28: 2436-48. PMID 23737439 DOI: 10.1002/Jbmr.2003  0.501
2013 Lau KH, Baylink DJ, Zhou XD, Rodriguez D, Bonewald LF, Li Z, Ruffoni D, Müller R, Kesavan C, Sheng MH. Osteocyte-derived insulin-like growth factor I is essential for determining bone mechanosensitivity. American Journal of Physiology. Endocrinology and Metabolism. 305: E271-81. PMID 23715728 DOI: 10.1152/Ajpendo.00092.2013  0.441
2013 Bonewald LF, Kiel DP, Clemens TL, Esser K, Orwoll ES, O'Keefe RJ, Fielding RA. Forum on bone and skeletal muscle interactions: summary of the proceedings of an ASBMR workshop. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 28: 1857-65. PMID 23671010 DOI: 10.1002/Jbmr.1980  0.419
2013 Bi L, Rahaman MN, Day DE, Brown Z, Samujh C, Liu X, Mohammadkhah A, Dusevich V, Eick JD, Bonewald LF. Effect of bioactive borate glass microstructure on bone regeneration, angiogenesis, and hydroxyapatite conversion in a rat calvarial defect model. Acta Biomaterialia. 9: 8015-26. PMID 23643606 DOI: 10.1016/J.Actbio.2013.04.043  0.479
2013 Dallas SL, Prideaux M, Bonewald LF. The osteocyte: an endocrine cell ... and more. Endocrine Reviews. 34: 658-90. PMID 23612223 DOI: 10.1210/Er.2012-1026  0.528
2013 Liu X, Rahaman MN, Liu Y, Bal BS, Bonewald LF. Enhanced bone regeneration in rat calvarial defects implanted with surface-modified and BMP-loaded bioactive glass (13-93) scaffolds. Acta Biomaterialia. 9: 7506-17. PMID 23567939 DOI: 10.1016/J.Actbio.2013.03.039  0.47
2013 Bonewald LF, Kneissel M, Johnson M. Preface: the osteocyte. Bone. 54: 181. PMID 23486185 DOI: 10.1016/J.Bone.2013.02.018  0.372
2013 Touchberry CD, Green TM, Tchikrizov V, Mannix JE, Mao TF, Carney BW, Girgis M, Vincent RJ, Wetmore LA, Dawn B, Bonewald LF, Stubbs JR, Wacker MJ. FGF23 is a novel regulator of intracellular calcium and cardiac contractility in addition to cardiac hypertrophy. American Journal of Physiology. Endocrinology and Metabolism. 304: E863-73. PMID 23443925 DOI: 10.1152/Ajpendo.00596.2012  0.323
2013 Kim JY, Lee SK, Jo KJ, Song DY, Lim DM, Park KY, Bonewald LF, Kim BJ. Exendin-4 increases bone mineral density in type 2 diabetic OLETF rats potentially through the down-regulation of SOST/sclerostin in osteocytes. Life Sciences. 92: 533-40. PMID 23357248 DOI: 10.1016/J.Lfs.2013.01.001  0.441
2013 Fulzele K, Krause DS, Panaroni C, Saini V, Barry KJ, Liu X, Lotinun S, Baron R, Bonewald L, Feng JQ, Chen M, Weinstein LS, Wu JY, Kronenberg HM, Scadden DT, et al. Myelopoiesis is regulated by osteocytes through Gsα-dependent signaling. Blood. 121: 930-9. PMID 23160461 DOI: 10.1182/Blood-2012-06-437160  0.526
2013 Ito N, Findlay DM, Anderson PH, Bonewald LF, Atkins GJ. Extracellular phosphate modulates the effect of 1α,25-dihydroxy vitamin D3 (1,25D) on osteocyte like cells. The Journal of Steroid Biochemistry and Molecular Biology. 136: 183-6. PMID 23064198 DOI: 10.1016/J.Jsbmb.2012.09.029  0.305
2013 Sheng MH, Zhou XD, Bonewald LF, Baylink DJ, Lau KH. Disruption of the insulin-like growth factor-1 gene in osteocytes impairs developmental bone growth in mice. Bone. 52: 133-44. PMID 23032105 DOI: 10.1016/J.Bone.2012.09.027  0.487
2013 Bonewald LF, Wacker MJ. FGF23 production by osteocytes. Pediatric Nephrology (Berlin, Germany). 28: 563-8. PMID 22983423 DOI: 10.1007/S00467-012-2309-3  0.359
2012 Mo C, Romero-Suarez S, Bonewald L, Johnson M, Brotto M. Prostaglandin E2: from clinical applications to its potential role in bone- muscle crosstalk and myogenic differentiation. Recent Patents On Biotechnology. 6: 223-9. PMID 23092433 DOI: 10.2174/1872208311206030223  0.379
2012 Jähn K, Lara-Castillo N, Brotto L, Mo CL, Johnson ML, Brotto M, Bonewald LF. Skeletal muscle secreted factors prevent glucocorticoid-induced osteocyte apoptosis through activation of β-catenin. European Cells & Materials. 24: 197-209; discussion . PMID 22972510 DOI: 10.22203/Ecm.V024A14  0.347
2012 Bi L, Jung S, Day D, Neidig K, Dusevich V, Eick D, Bonewald L. Evaluation of Bone Regeneration, Angiogenesis, and Hydroxyapatite Conversion in Critical-sized Rat Calvarial Defects Implanted with Bioactive Glass Scaffolds Journal of Biomedical Materials Research Part A. 100: 3267-3275. PMID 22733586 DOI: 10.1002/Jbm.A.34272  0.389
2012 Stern AR, Stern MM, Van Dyke ME, Jähn K, Prideaux M, Bonewald LF. Isolation and culture of primary osteocytes from the long bones of skeletally mature and aged mice. Biotechniques. 52: 361-73. PMID 22668415 DOI: 10.2144/0000113876  0.528
2012 Lieben L, Masuyama R, Torrekens S, Van Looveren R, Schrooten J, Baatsen P, Lafage-Proust MH, Dresselaers T, Feng JQ, Bonewald LF, Meyer MB, Pike JW, Bouillon R, Carmeliet G. Normocalcemia is maintained in mice under conditions of calcium malabsorption by vitamin D-induced inhibition of bone mineralization. The Journal of Clinical Investigation. 122: 1803-15. PMID 22523068 DOI: 10.1172/Jci45890  0.446
2012 Qing H, Ardeshirpour L, Pajevic PD, Dusevich V, Jähn K, Kato S, Wysolmerski J, Bonewald LF. Demonstration of osteocytic perilacunar/canalicular remodeling in mice during lactation. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 27: 1018-29. PMID 22308018 DOI: 10.1002/Jbmr.1567  0.485
2012 Eick JD, Barragan-Adjemian C, Rosser J, Melander JR, Dusevich V, Weiler RA, Miller BD, Kilway KV, Dallas MR, Bi L, Nalvarte EL, Bonewald LF. Silorane resin supports proliferation, differentiation, and mineralization of MLO-A5 bone cells in vitro and bone formation in vivo. Journal of Biomedical Materials Research. Part B, Applied Biomaterials. 100: 850-61. PMID 22278990 DOI: 10.1002/Jbm.B.32649  0.518
2012 Delgado-Calle J, Sañudo C, Bolado A, Fernández AF, Arozamena J, Pascual-Carra MA, Rodriguez-Rey JC, Fraga MF, Bonewald L, Riancho JA. DNA methylation contributes to the regulation of sclerostin expression in human osteocytes. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 27: 926-37. PMID 22162201 DOI: 10.1002/Jbmr.1491  0.366
2012 Rosser J, Bonewald LF. Studying osteocyte function using the cell lines MLO-Y4 and MLO-A5. Methods in Molecular Biology (Clifton, N.J.). 816: 67-81. PMID 22130923 DOI: 10.1007/978-1-61779-415-5_6  0.345
2012 Montesi M, Beraudi A, Jahn K, Stea S, Bonewald L. ORP 150 expression in hypoxic osteocytes in vitro Bone. 50. DOI: 10.1016/J.Bone.2012.02.283  0.313
2012 Delgado-Calle⁎ J, Arozamena J, Sañudo C, Pascual-Carra MA, Sumillera M, Bonewald L, Riancho JA. CpG demethylation is critical for sclerostin expression in human osteoblastic cells Bone. 50. DOI: 10.1016/J.Bone.2012.02.172  0.364
2012 Rahaman MN, Liu X, Bal BS, Day DE, Bi L, Bonewald LF. Bioactive Glass in Bone Tissue Engineering Ceramic Transactions. 237: 73-82. DOI: 10.1002/9781118511466.Ch8  0.405
2011 Wijenayaka AR, Kogawa M, Lim HP, Bonewald LF, Findlay DM, Atkins GJ. Sclerostin stimulates osteocyte support of osteoclast activity by a RANKL-dependent pathway. Plos One. 6: e25900. PMID 21991382 DOI: 10.1371/Journal.Pone.0025900  0.492
2011 Nakashima T, Hayashi M, Fukunaga T, Kurata K, Oh-Hora M, Feng JQ, Bonewald LF, Kodama T, Wutz A, Wagner EF, Penninger JM, Takayanagi H. Evidence for osteocyte regulation of bone homeostasis through RANKL expression. Nature Medicine. 17: 1231-4. PMID 21909105 DOI: 10.1038/Nm.2452  0.53
2011 Woo SM, Rosser J, Dusevich V, Kalajzic I, Bonewald LF. Cell line IDG-SW3 replicates osteoblast-to-late-osteocyte differentiation in vitro and accelerates bone formation in vivo. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 26: 2634-46. PMID 21735478 DOI: 10.1002/Jbmr.465  0.519
2011 Jia J, Yao W, Guan M, Dai W, Shahnazari M, Kar R, Bonewald L, Jiang JX, Lane NE. Glucocorticoid dose determines osteocyte cell fate. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 25: 3366-76. PMID 21705669 DOI: 10.1096/Fj.11-182519  0.422
2011 Bonewald L. The holy grail of high bone mass. Nature Medicine. 17: 657-658. PMID 21647140 DOI: 10.1038/Nm0611-657  0.498
2011 Zhang R, Lu Y, Ye L, Yuan B, Yu S, Qin C, Xie Y, Gao T, Drezner MK, Bonewald LF, Feng JQ. Unique roles of phosphorus in endochondral bone formation and osteocyte maturation. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 26: 1047-56. PMID 21542006 DOI: 10.1002/Jbmr.294  0.526
2011 Xiao Z, Dallas M, Qiu N, Nicolella D, Cao L, Johnson M, Bonewald L, Quarles LD. Conditional deletion of Pkd1 in osteocytes disrupts skeletal mechanosensing in mice. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 25: 2418-32. PMID 21454365 DOI: 10.1096/Fj.10-180299  0.468
2011 Rahaman MN, Day DE, Bal BS, Fu Q, Jung SB, Bonewald LF, Tomsia AP. Bioactive glass in tissue engineering. Acta Biomaterialia. 7: 2355-73. PMID 21421084 DOI: 10.1016/J.Actbio.2011.03.016  0.407
2011 Zhang J, Tu Q, Bonewald LF, He X, Stein G, Lian J, Chen J. Effects of miR-335-5p in modulating osteogenic differentiation by specifically downregulating Wnt antagonist DKK1. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 26: 1953-63. PMID 21351149 DOI: 10.1002/Jbmr.377  0.304
2011 Bonewald LF. The amazing osteocyte. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 26: 229-38. PMID 21254230 DOI: 10.1002/Jbmr.320  0.526
2011 Lu Y, Yuan B, Qin C, Cao Z, Xie Y, Dallas SL, McKee MD, Drezner MK, Bonewald LF, Feng JQ. The biological function of DMP-1 in osteocyte maturation is mediated by its 57-kDa C-terminal fragment. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 26: 331-40. PMID 20734454 DOI: 10.1002/Jbmr.226  0.426
2011 Krause DS, Fulzele K, Barry K, Lotinun S, Baron R, Bonewald L, Feng JQ, Chen M, Weinstein LS, Bouxsein M, Scadden DT, Divieti-Pajevic P. Osteocytes Support Hematopoiesis by Altering the Bone Marrow Microenvironment Through Gsα Signaling Blood. 118: 219-219. DOI: 10.1182/Blood.V118.21.219.219  0.519
2010 Guo D, Keightley A, Guthrie J, Veno PA, Harris SE, Bonewald LF. Identification of osteocyte-selective proteins. Proteomics. 10: 3688-98. PMID 20845334 DOI: 10.1002/Pmic.201000306  0.731
2010 Kitase Y, Barragan L, Qing H, Kondoh S, Jiang JX, Johnson ML, Bonewald LF. Mechanical induction of PGE2 in osteocytes blocks glucocorticoid-induced apoptosis through both the β-catenin and PKA pathways. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 25: 2657-68. PMID 20578217 DOI: 10.1002/Jbmr.168  0.304
2010 Xia X, Kar R, Gluhak-Heinrich J, Yao W, Lane NE, Bonewald LF, Biswas SK, Lo WK, Jiang JX. Glucocorticoid-induced autophagy in osteocytes. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 25: 2479-88. PMID 20564240 DOI: 10.1002/Jbmr.160  0.341
2010 Fu Q, Rahaman MN, Bal BS, Bonewald LF, Kuroki K, Brown RF. Silicate, borosilicate, and borate bioactive glass scaffolds with controllable degradation rate for bone tissue engineering applications. II. In vitro and in vivo biological evaluation. Journal of Biomedical Materials Research. Part A. 95: 172-9. PMID 20540099 DOI: 10.1002/Jbm.A.32823  0.402
2010 Kramer I, Halleux C, Keller H, Pegurri M, Gooi JH, Weber PB, Feng JQ, Bonewald LF, Kneissel M. Osteocyte Wnt/beta-catenin signaling is required for normal bone homeostasis. Molecular and Cellular Biology. 30: 3071-85. PMID 20404086 DOI: 10.1128/Mcb.01428-09  0.522
2010 Dallas SL, Bonewald LF. Dynamics of the transition from osteoblast to osteocyte. Annals of the New York Academy of Sciences. 1192: 437-43. PMID 20392270 DOI: 10.1111/J.1749-6632.2009.05246.X  0.521
2010 Rath AL, Bonewald LF, Ling J, Jiang JX, Van Dyke ME, Nicolella DP. Correlation of cell strain in single osteocytes with intracellular calcium, but not intracellular nitric oxide, in response to fluid flow. Journal of Biomechanics. 43: 1560-4. PMID 20189178 DOI: 10.1016/J.Jbiomech.2010.01.030  0.313
2010 Wang L, Dormer NH, Bonewald LF, Detamore MS. Osteogenic differentiation of human umbilical cord mesenchymal stromal cells in polyglycolic acid scaffolds. Tissue Engineering. Part A. 16: 1937-48. PMID 20070186 DOI: 10.1089/Ten.Tea.2009.0706  0.45
2010 Xia X, Batra N, Shi Q, Bonewald LF, Sprague E, Jiang JX. Prostaglandin promotion of osteocyte gap junction function through transcriptional regulation of connexin 43 by glycogen synthase kinase 3/beta-catenin signaling. Molecular and Cellular Biology. 30: 206-19. PMID 19841066 DOI: 10.1128/Mcb.01844-08  0.332
2010 Kato Y, Windle JJ, Koop BA, Mundy GR, Bonewald LF. Establishment of an osteocyte-like cell line, MLO-Y4 Journal of Bone and Mineral Research. 12: 2014-2023. PMID 9421234 DOI: 10.1359/Jbmr.1997.12.12.2014  0.489
2010 Bonewald LF. The Osteocyte Network as a Source and Reservoir of Signaling Factors Endocrinology and Metabolism. 25: 161-165. DOI: 10.3803/Enm.2010.25.3.161  0.461
2010 Dallas SL, Bonewald LF. Unraveling osteocyte signaling networks: Meeting report from the 31st Annual Meeting of the American Society for Bone and Mineral Research Ibms Bonekey. 7: 88-92. DOI: 10.1138/20100431  0.384
2010 Bonewald LF. Osteocytes and bone homeostasis Bone. 47. DOI: 10.1016/J.Bone.2010.09.047  0.486
2010 Lau SH, Bonewald LF, Fong T, Hunter L, Gelb J. Imaging bone morphology down to submicron and nanoscale with lab based CT Bone. 47. DOI: 10.1016/J.Bone.2010.04.384  0.374
2009 Guo D, Bonewald LF. Advancing our understanding of osteocyte cell biology. Therapeutic Advances in Musculoskeletal Disease. 1: 87-96. PMID 22870430 DOI: 10.1177/1759720X09341484  0.771
2009 Qing H, Bonewald LF. Osteocyte remodeling of the perilacunar and pericanalicular matrix. International Journal of Oral Science. 1: 59-65. PMID 20687297 DOI: 10.4248/Ijos.09019  0.307
2009 Amano S, Sekine K, Bonewald LF, Ohmori Y. A novel osteoclast precursor cell line, 4B12, recapitulates the features of primary osteoclast differentiation and function: enhanced transfection efficiency before and after differentiation. Journal of Cellular Physiology. 221: 40-53. PMID 19492422 DOI: 10.1002/Jcp.21827  0.438
2009 Sittichockechaiwut A, Scutt AM, Ryan AJ, Bonewald LF, Reilly GC. Use of rapidly mineralising osteoblasts and short periods of mechanical loading to accelerate matrix maturation in 3D scaffolds. Bone. 44: 822-9. PMID 19442630 DOI: 10.1016/J.Bone.2008.12.027  0.334
2009 Wang L, Singh M, Bonewald LF, Detamore MS. Signalling strategies for osteogenic differentiation of human umbilical cord mesenchymal stromal cells for 3D bone tissue engineering. Journal of Tissue Engineering and Regenerative Medicine. 3: 398-404. PMID 19434662 DOI: 10.1002/Term.176  0.457
2009 Henriksen K, Neutzsky-Wulff AV, Bonewald LF, Karsdal MA. Local communication on and within bone controls bone remodeling. Bone. 44: 1026-33. PMID 19345750 DOI: 10.1016/J.Bone.2009.03.671  0.511
2009 Farrow EG, Davis SI, Ward LM, Summers LJ, Bubbear JS, Keen R, Stamp TC, Baker LR, Bonewald LF, White KE. Molecular analysis of DMP1 mutants causing autosomal recessive hypophosphatemic rickets. Bone. 44: 287-94. PMID 19007919 DOI: 10.1016/J.Bone.2008.10.040  0.319
2009 Yang W, Harris MA, Heinrich JG, Guo D, Bonewald LF, Harris SE. Gene expression signatures of a fibroblastoid preosteoblast and cuboidal osteoblast cell model compared to the MLO-Y4 osteocyte cell model. Bone. 44: 32-45. PMID 18973839 DOI: 10.1016/J.Bone.2008.08.133  0.734
2009 Lu Y, Qin C, Xie Y, Bonewald LF, Feng JQ. Studies of the DMP1 57-kDa functional domain both in vivo and in vitro. Cells, Tissues, Organs. 189: 175-85. PMID 18728349 DOI: 10.1159/000151727  0.436
2009 Barragan-Adjemian C, Lausten L, Ang DB, Johnson M, Katz J, Bonewald LF. Bisphosphonate-related osteonecrosis of the jaw: model and diagnosis with cone beam computerized tomography. Cells Tissues Organs. 189: 284-288. PMID 18703870 DOI: 10.1159/000151451  0.355
2009 Peng T, Huang B, Sun Y, Lu Y, Bonewald L, Chen S, Butler WT, Feng JQ, D'Souza RN, Qin C. Blocking of proteolytic processing and deletion of glycosaminoglycan side chain of mouse DMP1 by substituting critical amino acid residues. Cells, Tissues, Organs. 189: 192-7. PMID 18698130 DOI: 10.1159/000151373  0.307
2009 Maciejewska I, Qin D, Huang B, Sun Y, Mues G, Svoboda K, Bonewald L, Butler WT, Feng JQ, Qin C. Distinct compartmentalization of dentin matrix protein 1 fragments in mineralized tissues and cells. Cells, Tissues, Organs. 189: 186-91. PMID 18698129 DOI: 10.1159/000151372  0.439
2009 Garcia C, Boyce BF, Gilles J, Dallas M, Qiao M, Mundy GR, Bonewald LF. Leukotriene B4 stimulates osteoclastic bone resorption both in vitro and in vivo. Journal of Bone and Mineral Research. 11: 1619-1627. PMID 8915769 DOI: 10.1002/Jbmr.5650111105  0.503
2009 Harris SE, Bonewald L, Harris MA, Sabatini M, Dallas S, Feng JQ, Ghosh-Choudhury N, Wozney J, Mundy GR. Effects of transforming growth factor β on bone nodule formation and expression of bone morphogenetic protein 2, osteocalcin, osteopontin, alkaline phosphatase, and type I collagen mRNA in long-term cultures of fetal rat calvarial osteoblasts Journal of Bone and Mineral Research. 9: 855-863. PMID 8079661 DOI: 10.1002/Jbmr.5650090611  0.48
2009 Yao X, Bonewald LF, Eick JD, Wang Y. Quantitative mechanical/chemical imaging of bone from Dmp1 null mice Mrs Proceedings. 1187: 187-192. DOI: 10.1557/Proc-1187-Kk10-05  0.487
2009 Bonewald LF, Dallas SL, Gorski JP. 10. Bone Mineralization Cold Spring Harbor Monograph Archive. 53: 277-295. DOI: 10.1101/087969825.53.277  0.52
2008 Dallas SL, Veno PA, Rosser JL, Barragan-Adjemian C, Rowe DW, Kalajzic I, Bonewald LF. Time lapse imaging techniques for comparison of mineralization dynamics in primary murine osteoblasts and the late osteoblast/early osteocyte-like cell line MLO-A5 Cells Tissues Organs. 189: 6-11. PMID 18728354 DOI: 10.1159/000151745  0.423
2008 Siller-Jackson AJ, Burra S, Gu S, Xia X, Bonewald LF, Sprague E, Jiang JX. Adaptation of connexin 43-hemichannel prostaglandin release to mechanical loading. The Journal of Biological Chemistry. 283: 26374-82. PMID 18676366 DOI: 10.1074/Jbc.M803136200  0.389
2008 Rios HF, Ma D, Xie Y, Giannobile WV, Bonewald LF, Conway SJ, Feng JQ. Periostin is essential for the integrity and function of the periodontal ligament during occlusal loading in mice Journal of Periodontology. 79: 1480-1490. PMID 18672999 DOI: 10.1902/Jop.2008.070624  0.374
2008 Huang B, Maciejewska I, Sun Y, Peng T, Qin D, Lu Y, Bonewald L, Butler WT, Feng J, Qin C. Identification of full-length dentin matrix protein 1 in dentin and bone Calcified Tissue International. 82: 401-410. PMID 18488132 DOI: 10.1007/S00223-008-9140-7  0.465
2008 Bonewald LF, Johnson ML. Osteocytes, mechanosensing and Wnt signaling. Bone. 42: 606-15. PMID 18280232 DOI: 10.1016/J.Bone.2007.12.224  0.524
2008 Feng JQ, Scott G, Guo D, Jiang B, Harris M, Ward T, Ray M, Bonewald LF, Harris SE, Mishina Y. Generation of a conditional null allele for Dmp1 in mouse. Genesis (New York, N.Y. : 2000). 46: 87-91. PMID 18257058 DOI: 10.1002/Dvg.20370  0.703
2008 Dallas SL, Bonewald LF. Osteocytes play to standing room only: Meeting report from the 30th Annual Meeting of the American Society for Bone and Mineral Research Ibms Bonekey. 5: 441-445. DOI: 10.1138/20080351  0.397
2007 Bonewald LF. Osteocytes as dynamic multifunctional cells. Annals of the New York Academy of Sciences. 1116: 281-90. PMID 17646259 DOI: 10.1196/Annals.1402.018  0.517
2007 Bonewald LF. Osteocyte messages from a bony tomb. Cell Metabolism. 5: 410-1. PMID 17550775 DOI: 10.1016/J.Cmet.2007.05.008  0.505
2007 Lu Y, Xie Y, Zhang S, Dusevich V, Bonewald LF, Feng JQ. DMP1-targeted Cre Expression in Odontoblasts and Osteocytes Journal of Dental Research. 86: 320-325. PMID 17384025 DOI: 10.1177/154405910708600404  0.434
2007 Kono SJ, Oshima Y, Hoshi K, Bonewald LF, Oda H, Nakamura K, Kawaguchi H, Tanaka S. Erk pathways negatively regulate matrix mineralization. Bone. 40: 68-74. PMID 16978937 DOI: 10.1016/J.Bone.2006.07.024  0.424
2007 Dallas SL, Bonewald LF. Osteocytes emerging from obscurity. Meeting report from the 29th Annual Meeting of the American Society for Bone and Mineral Research Bonekey Reports. 4: 337-341. DOI: 10.1138/20070286  0.395
2006 Bonewald LF. Mechanosensation and Transduction in Osteocytes. Bonekey Osteovision. 3: 7-15. PMID 17415409 DOI: 10.1138/20060233  0.431
2006 Barragan-Adjemian C, Nicolella D, Dusevich V, Dallas MR, Eick JD, Bonewald LF. Mechanism by which MLO-A5 late osteoblasts/early osteocytes mineralize in culture: similarities with mineralization of lamellar bone. Calcified Tissue International. 79: 340-53. PMID 17115241 DOI: 10.1007/S00223-006-0107-2  0.476
2006 Feng JQ, Ward LM, Liu S, Lu Y, Xie Y, Yuan B, Yu X, Rauch F, Davis SI, Zhang S, Rios H, Drezner MK, Quarles LD, Bonewald LF, White KE. Loss of DMP1 causes rickets and osteomalacia and identifies a role for osteocytes in mineral metabolism. Nature Genetics. 38: 1310-5. PMID 17033621 DOI: 10.1038/Ng1905  0.515
2006 Xiao Z, Zhang S, Mahlios J, Zhou G, Magenheimer BS, Guo D, Dallas SL, Maser R, Calvet JP, Bonewald L, Quarles LD. Cilia-like structures and polycystin-1 in osteoblasts/osteocytes and associated abnormalities in skeletogenesis and Runx2 expression. The Journal of Biological Chemistry. 281: 30884-95. PMID 16905538 DOI: 10.1074/Jbc.M604772200  0.746
2006 Zhang K, Barragan-Adjemian C, Ye L, Kotha S, Dallas M, Lu Y, Zhao S, Harris M, Harris SE, Feng JQ, Bonewald LF. E11/gp38 selective expression in osteocytes: regulation by mechanical strain and role in dendrite elongation. Molecular and Cellular Biology. 26: 4539-52. PMID 16738320 DOI: 10.1128/Mcb.02120-05  0.505
2006 Lane NE, Yao W, Balooch M, Nalla RK, Balooch G, Habelitz S, Kinney JH, Bonewald LF. Glucocorticoid-treated mice have localized changes in trabecular bone material properties and osteocyte lacunar size that are not observed in placebo-treated or estrogen-deficient mice. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 21: 466-76. PMID 16491295 DOI: 10.1359/Jbmr.051103  0.495
2006 Nicolella DP, Moravits DE, Gale AM, Bonewald LF, Lankford J. Osteocyte lacunae tissue strain in cortical bone. Journal of Biomechanics. 39: 1735-43. PMID 15993413 DOI: 10.1016/J.Jbiomech.2005.04.032  0.464
2005 Nicolella DP, Bonewald LF, Moravits DE, Lankford J. Measurement of microstructural strain in cortical bone. European Journal of Morphology. 42: 23-9. PMID 16123021 DOI: 10.1080/09243860500095364  0.46
2005 Cherian PP, Siller-Jackson AJ, Gu S, Wang X, Bonewald LF, Sprague E, Jiang JX. Mechanical strain opens connexin 43 hemichannels in osteocytes: a novel mechanism for the release of prostaglandin. Molecular Biology of the Cell. 16: 3100-6. PMID 15843434 DOI: 10.1091/Mbc.E04-10-0912  0.359
2005 Yang W, Lu Y, Kalajzic I, Guo D, Harris MA, Gluhak-Heinrich J, Kotha S, Bonewald LF, Feng JQ, Rowe DW, Turner CH, Robling AG, Harris SE. Dentin matrix protein 1 gene cis-regulation: use in osteocytes to characterize local responses to mechanical loading in vitro and in vivo. The Journal of Biological Chemistry. 280: 20680-90. PMID 15728181 DOI: 10.1074/Jbc.M500104200  0.754
2005 Ye L, Mishina Y, Chen D, Huang H, Dallas SL, Dallas MR, Sivakumar P, Kunieda T, Tsutsui TW, Boskey A, Bonewald LF, Feng JQ. Dmp1-deficient mice display severe defects in cartilage formation responsible for a chondrodysplasia-like phenotype. The Journal of Biological Chemistry. 280: 6197-203. PMID 15590631 DOI: 10.1074/Jbc.M412911200  0.49
2004 Yang W, Kalajzic I, Lu Y, Guo D, Harris MA, Gluhak-Heinrich J, Bonewald LF, Feng JQ, Rowe DW, Harris SE. In vitro and in vivo study on osteocyte-specific mechanical signaling pathways Journal of Musculoskeletal Neuronal Interactions. 4: 386-387. PMID 15758272  0.655
2003 Cherian PP, Cheng B, Gu S, Sprague E, Bonewald LF, Jiang JX. Effects of mechanical strain on the function of Gap junctions in osteocytes are mediated through the prostaglandin EP2 receptor. The Journal of Biological Chemistry. 278: 43146-56. PMID 12939279 DOI: 10.1074/Jbc.M302993200  0.359
2003 Gluhak-Heinrich J, Ye L, Bonewald LF, Feng JQ, MacDougall M, Harris SE, Pavlin D. Mechanical loading stimulates dentin matrix protein 1 (DMP1) expression in osteocytes in vivo. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 18: 807-17. PMID 12733719 DOI: 10.1359/Jbmr.2003.18.5.807  0.504
2003 Bonewald LF, Harris SE, Rosser J, Dallas MR, Dallas SL, Camacho NP, Boyan B, Boskey A. von Kossa staining alone is not sufficient to confirm that mineralization in vitro represents bone formation. Calcified Tissue International. 72: 537-47. PMID 12724828 DOI: 10.1007/S00223-002-1057-Y  0.394
2003 Ahuja SS, Zhao S, Bellido T, Plotkin LI, Jimenez F, Bonewald LF. CD40 ligand blocks apoptosis induced by tumor necrosis factor alpha, glucocorticoids, and etoposide in osteoblasts and the osteocyte-like cell line murine long bone osteocyte-Y4. Endocrinology. 144: 1761-9. PMID 12697681 DOI: 10.1210/En.2002-221136  0.411
2003 Lohmann CH, Schwartz Z, Liu Y, Li Z, Simon BJ, Sylvia VL, Dean DD, Bonewald LF, Donahue HJ, Boyan BD. Pulsed electromagnetic fields affect phenotype and connexin 43 protein expression in MLO-Y4 osteocyte-like cells and ROS 17/2.8 osteoblast-like cells. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 21: 326-34. PMID 12568966 DOI: 10.1016/S0736-0266(02)00137-7  0.423
2002 Zhao S, Kato Y, Zhang Y, Harris S, Ahuja SS, Bonewald LF. MLO-Y4 osteocyte-like cells support osteoclast formation and activation Journal of Bone and Mineral Research. 17: 2068-2079. PMID 12412815 DOI: 10.1359/Jbmr.2002.17.11.2068  0.453
2002 Boyan BD, Bonewald LF, Paschalis EP, Lohmann CH, Rosser J, Cochran DL, Dean DD, Schwartz Z, Boskey AL. Osteoblast-mediated mineral deposition in culture is dependent on surface microtopography. Calcified Tissue International. 71: 519-29. PMID 12232675 DOI: 10.1007/S00223-001-1114-Y  0.377
2002 Dallas SL, Rosser JL, Mundy GR, Bonewald LF. Proteolysis of latent transforming growth factor-β (TGF-β)-binding protein-1 by osteoclasts. A cellular mechanism for release of TGF-β from bone matrix Journal of Biological Chemistry. 277: 21352-21360. PMID 11929865 DOI: 10.1074/Jbc.M111663200  0.378
2001 Kato Y, Boskey A, Spevak L, Dallas M, Hori M, Bonewald LF. Establishment of an Osteoid Preosteocyte-like Cell MLO-A5 That Spontaneously Mineralizes in Culture Journal of Bone and Mineral Research. 16: 1622-1633. PMID 11547831 DOI: 10.1359/Jbmr.2001.16.9.1622  0.422
2001 Cheng B, Zhao S, Luo J, Sprague E, Bonewald LF, Jiang JX. Expression of functional gap junctions and regulation by fluid flow in osteocyte-like MLO-Y4 cells. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 16: 249-59. PMID 11204425 DOI: 10.1359/Jbmr.2001.16.2.249  0.386
2000 Lohmann CH, Bonewald LF, Sisk MA, Sylvia VL, Cochran DL, Dean DD, Boyan BD, Schwartz Z. Maturation state determines the response of osteogenic cells to surface roughness and 1,25-dihydroxyvitamin D3. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 15: 1169-80. PMID 10841186 DOI: 10.1359/Jbmr.2000.15.6.1169  0.343
2000 Schwartz Z, Lohmann CH, Wieland M, Cochran DL, Dean DD, Textor M, Bonewald LF, Boyan BD. Osteoblast proliferation and differentiation on dentin slices are modulated by pretreatment of the surface with tetracycline or osteoclasts. Journal of Periodontology. 71: 586-97. PMID 10807123 DOI: 10.1902/Jop.2000.71.4.586  0.404
2000 Dallas SL, Keene DR, Bruder SP, Saharinen J, Sakai LY, Mundy GR, Bonewald LF. Role of the latent transforming growth factor beta binding protein 1 in fibrillin-containing microfibrils in bone cells in vitro and in vivo. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 15: 68-81. PMID 10646116 DOI: 10.1359/Jbmr.2000.15.1.68  0.485
1999 Schwartz Z, Lohmann CH, Oefinger J, Bonewald LF, Dean DD, Boyan BD. Implant surface characteristics modulate differentiation behavior of cells in the osteoblastic lineage. Advances in Dental Research. 13: 38-48. PMID 11276745 DOI: 10.1177/08959374990130011301  0.349
1999 Horiuchi K, Amizuka N, Takeshita S, Takamatsu H, Katsuura M, Ozawa H, Toyama Y, Bonewald LF, Kudo A. Identification and characterization of a novel protein, periostin, with restricted expression to periosteum and periodontal ligament and increased expression by transforming growth factor β Journal of Bone and Mineral Research. 14: 1239-1249. PMID 10404027 DOI: 10.1359/Jbmr.1999.14.7.1239  0.417
1999 Bonewald LF. Establishment and characterization of an osteocyte-like cell line, MLO-Y4. Journal of Bone and Mineral Metabolism. 17: 61-65. PMID 10084404 DOI: 10.1007/S007740050066  0.422
1999 Flynn MA, Qiao M, Garcia C, Dallas M, Bonewald L. Avian Osteoclast Cells are Stimulated to Resorb Calcified Matrices by and Possess Receptors for Leukotriene B4 Calcified Tissue International. 64: 154-159. PMID 9914324 DOI: 10.1007/S002239900595  0.382
1998 Traianedes K, Dallas MR, Garrett IR, Mundy GR, Bonewald LF. 5-Lipoxygenase metabolites inhibit bone formation in vitro. Endocrinology. 139: 3178-84. PMID 9645691 DOI: 10.1210/Endo.139.7.6115  0.509
1998 Bonewald LF, Dallas SL. The Role of Growth Factors in Bone Formation Advances in Organ Biology. 5: 591-613. DOI: 10.1016/S1569-2590(08)60137-8  0.381
1997 Gilles JA, Carnes DL, Dallas MR, Holt SC, Bonewald LF. Oral bone loss is increased in ovariectomized rats. Journal of Endodontics. 23: 419-22. PMID 9587293 DOI: 10.1016/S0099-2399(97)80294-4  0.429
1997 Bonewald LF, Flynn M, Qiao M, Dallas MR, Mundy GR, Boyce BF. Mice lacking 5-lipoxygenase have increased cortical bone thickness. Advances in Experimental Medicine and Biology. 433: 299-302. PMID 9561156 DOI: 10.1007/978-1-4899-1810-9_63  0.536
1996 Garcia C, Qiao M, Chen D, Kirchen M, Gallwitz W, Mundy GR, Bonewald LF. Effects of synthetic peptido-leukotrienes on bone resorption in vitro. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 11: 521-9. PMID 8992883 DOI: 10.1002/Jbmr.5650110413  0.421
1996 Raval P, Hsu HH, Schneider DJ, Sarras MP, Masuhara K, Bonewald LF, Anderson HC. Expression of bone morphogenetic proteins by osteoinductive and non-osteoinductive human osteosarcoma cells. Journal of Dental Research. 75: 1518-23. PMID 8876605 DOI: 10.1177/00220345960750071301  0.495
1995 Mundy GR, Boyce B, Hughes D, Wright KR, Bonewald L, Dallas S, Harris S, Ghosh-Choudhury N, Chen D, Dunstan C, Izbicka E, Yoneda T. The effects of cytokines and growth factors on osteoblastic cells Bone. 17. PMID 8579902 DOI: 10.1016/8756-3282(95)00182-D  0.507
1995 Dallas SL, Miyazono K, Skerry TM, Mundy GR, Bonewald LF. Dual role for the latent transforming growth factor-beta binding protein in storage of latent TGF-beta in the extracellular matrix and as a structural matrix protein. Journal of Cell Biology. 131: 539-549. PMID 7593177 DOI: 10.1083/Jcb.131.2.539  0.354
1994 Dean DD, Schwartz Z, Bonewald L, Muniz OE, Morales S, Gomez R, Brooks BP, Qiao M, Howell DS, Boyan BD. Matrix vesicles produced by osteoblast-like cells in culture become significantly enriched in proteoglycan-degrading metalloproteinases after addition of beta-glycerophosphate and ascorbic acid. Calcified Tissue International. 54: 399-408. PMID 8062158 DOI: 10.1007/Bf00305527  0.328
1994 Bonewald L, Dallas SL. Role of active and latent transforming growth factor β in bone formation Journal of Cellular Biochemistry. 55: 350-357. PMID 7962167 DOI: 10.1002/Jcb.240550312  0.493
1993 Schwartz Z, Bonewald LF, Caulfield K, Brooks B, Boyan BD. Direct effects of transforming growth factor-β on chondrocytes are modulated by vitamin D metabolites in a cell maturation-specific manner Endocrinology. 132: 1544-1552. PMID 8462452 DOI: 10.1210/Endo.132.4.8462452  0.329
1993 Garrett IR, Guise TA, Bonewald LF, Chizzonite R, Mundy GR. Evidence that interleukin-1 mediates its effects on bone resorption via the 80 kilodalton interleukin-1 receptor Calcified Tissue International. 52: 438-441. PMID 8369991 DOI: 10.1007/Bf00571333  0.395
1993 Oreffo ROC, Marshall GJ, Kirchen M, Garcia C, Gallwitz WE, Chavez J, Mundy GR, Bonewald LF. Characterization of a cell line derived from a human giant cell tumor that stimulates osteoclastic bone resorption. Clinical Orthopaedics and Related Research. 229-241. DOI: 10.1097/00003086-199311000-00039  0.458
1992 Yates AJ, Boyce BF, Favarato G, Aufdemorte TB, Marcelli C, Kester MB, Walker R, Langton BC, Bonewald LF, Mundy GR. Expression of human transforming growth factor alpha by Chinese hamster ovarian tumors in nude mice causes hypercalcemia and increased osteoclastic bone resorption. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 7: 847-53. PMID 1642153 DOI: 10.1002/Jbmr.5650070715  0.411
1992 Bonewald LF, Schwartz Z, Swain LD, Boyan BD. Stimulation of matrix vesicle enzyme activity in osteoblast-like cells by 1,25(OH)2D3 and transforming growth factor β (TGFβ) Bone and Mineral. 17: 139-144. PMID 1611299 DOI: 10.1016/0169-6009(92)90725-S  0.317
1992 Schwartz Z, Dennis R, Bonewald L, Swain L, Gomez R, Boyan BD. Differential regulation of prostaglandin E2 synthesis and phospholipase A2 activity by 1,25-(OH)2D3 in three osteoblast-like cell lines (MC-3T3-E1, ROS 17/2.8, and MG-63) Bone. 13: 51-58. PMID 1581109 DOI: 10.1016/8756-3282(92)90361-Y  0.329
1991 Bonewald LF, Wakefield L, Oreffo RO, Escobedo A, Twardzik DR, Mundy GR. Latent forms of transforming growth factor-beta (TGF beta) derived from bone cultures: identification of a naturally occurring 100-kDa complex with similarity to recombinant latent TGF beta. Molecular Endocrinology (Baltimore, Md.). 5: 741-51. PMID 1922093 DOI: 10.1210/Mend-5-6-741  0.352
1991 Mundy GR, Roodman GD, Bonewald LF, Oreffo RO, Boyce BF. Assays for bone resorption and bone formation. Methods in Enzymology. 198: 502-10. PMID 1857238 DOI: 10.1016/0076-6879(91)98049-C  0.485
1990 Garrett IR, Boyce BF, Oreffo ROC, Bonewald L, Poser J, Mundy GR. Oxygen-derived free radicals stimulate osteoclastic bone resorption in rodent bone in vitro and in vivo. Journal of Clinical Investigation. 85: 632-639. PMID 2312718 DOI: 10.1172/Jci114485  0.493
1990 Pfeilschifter J, Bonewald L, Mundy GR. Characterization of the latent transforming growth factor ß complex in Bone Journal of Bone and Mineral Research. 5: 49-58. PMID 2309578 DOI: 10.1002/Jbmr.5650050109  0.328
1990 Bonewald LF, Schwartz Z, Swain LD, Ramirez V, Poser J, Boyan BD. Stimulation of plasma membrane and matrix vesicle enzyme activity by transforming growth factor-β in osteosarcoma cell cultures Journal of Cellular Physiology. 145: 200-206. PMID 2246323 DOI: 10.1002/Jcp.1041450203  0.398
1990 Mundy GR, Bonewald LF. Role of TGFβ in Bone Remodelinga Annals of the New York Academy of Sciences. 593: 91-97. PMID 2197964 DOI: 10.1111/J.1749-6632.1990.Tb16102.X  0.486
1990 Oreffo ROC, Bonewald L, Kukita A, Garrett IR, Seyedin SM, Rosen D, Mundy GR. Inhibitory Effects of the Bone-Derived Growth Factors Osteoinductive Factor and Transforming Growth Factor-β on Isolated Osteoclasts* Endocrinology. 126: 3069-3075. PMID 1693566 DOI: 10.1210/Endo-126-6-3069  0.441
1990 Bonewald LF, Mundy GR. Role of transforming growth factor-beta in bone remodeling. Clinical Orthopaedics and Related Research. 261-276. DOI: 10.1097/00003086-199001000-00036  0.449
1989 Oreffo ROC, Mundy GR, Seyedin SM, Bonewald LF. Activation of the bone-derived latent TGF beta complex by isolated osteoclasts. Biochemical and Biophysical Research Communications. 158: 817-823. PMID 2920041 DOI: 10.1016/0006-291X(89)92795-2  0.432
1989 Bonewald L, Mundy GR. Role of Transforming Growth Factor Beta in Bone Remodeling: A Review Connective Tissue Research. 23: 201-208. PMID 2698314 DOI: 10.3109/03008208909002418  0.384
1989 Boyan BD, Schwartz Z, Swain LD, Bonewald LF, Khare A. Regulation of matrix vesicle metabolism by vitamin d metabolites Connective Tissue Research. 22: 629-642. DOI: 10.3109/03008208909114115  0.328
1988 Sabatini M, Boyce B, Aufdemorte T, Bonewald L, Mundy GR. Infusions of recombinant human interleukins 1 alpha and 1 beta cause hypercalcemia in normal mice. Proceedings of the National Academy of Sciences of the United States of America. 85: 5235-5239. PMID 3260671 DOI: 10.1073/Pnas.85.14.5235  0.452
Show low-probability matches.