Russell P. Bowler - Publications

Affiliations: 
University of Colorado Anschutz Medical Campus, Denver, Aurora, CO 
Area:
Immunology, Cell Biology

232 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Huffman JE, Nicholas J, Hahn J, Heath AS, Raffield LM, Yanek LR, Brody JA, Thibord F, Almasy L, Bartz TM, Bielak LF, Bowler RP, Carrasquilla GD, Chasman DI, Chen MH, et al. Whole-genome analysis of plasma fibrinogen reveals population-differentiated genetic regulators with putative liver roles. Blood. PMID 39226462 DOI: 10.1182/blood.2023022596  0.394
2024 Konigsberg IR, Vu T, Liu W, Litkowski EM, Pratte KA, Vargas LB, Gilmore N, Abdel-Hafiz M, Manichaikul A, Cho MH, Hersh CP, DeMeo DL, Banaei-Kashani F, Bowler RP, Lange LA, et al. Proteomic networks and related genetic variants associated with smoking and chronic obstructive pulmonary disease. Bmc Genomics. 25: 825. PMID 39223457 DOI: 10.1186/s12864-024-10619-1  0.33
2024 Curtis JL, Bateman LA, Murray S, Couper DJ, Labaki WW, Freeman CM, Arnold KB, Christenson SA, Alexis NE, Kesimer M, Boucher RC, Kaner RJ, Barjaktarevic I, Cooper CB, Hoffman EA, ... ... Bowler RP, et al. Design of the SPIROMICS Study of Early COPD Progression: SOURCE Study. Chronic Obstructive Pulmonary Diseases (Miami, Fla.). PMID 39159077 DOI: 10.15326/jcopdf.2023.0490  0.344
2024 Ruvuna L, Hijazi K, Guzman DE, Guo C, Loureiro J, Khokhlovich E, Morris M, Obeidat M, Pratte KA, DiLillo KM, Sharma S, Kechris K, Anzueto A, Barjaktarevic I, Bleecker ER, ... ... Bowler RP, et al. Dynamic and prognostic proteomic associations with FEV decline in chronic obstructive pulmonary disease. Medrxiv : the Preprint Server For Health Sciences. PMID 39148837 DOI: 10.1101/2024.08.07.24311507  0.34
2024 Konigsberg IR, Vu T, Liu W, Litkowski EM, Pratte KA, Vargas LB, Gilmore N, Abdel-Hafiz M, Manichaikul AW, Cho MH, Hersh CP, DeMeo DL, Banaei-Kashani F, Bowler RP, Lange LA, et al. Proteomic Networks and Related Genetic Variants Associated with Smoking and Chronic Obstructive Pulmonary Disease. Medrxiv : the Preprint Server For Health Sciences. PMID 38464285 DOI: 10.1101/2024.02.26.24303069  0.33
2024 Choi B, Liu GY, Sheng Q, Amancherla K, Perry A, Huang X, San José Estépar R, Ash SY, Guan W, Jacobs DR, Martinez FJ, Rosas IO, Bowler RP, Kropski JA, Banovich NE, et al. Proteomic Biomarkers of Quantitative Interstitial Abnormalities in COPDGene and CARDIA Lung Study. American Journal of Respiratory and Critical Care Medicine. PMID 38285918 DOI: 10.1164/rccm.202307-1129OC  0.31
2023 Silverman EK, Kim AY, Make BJ, Regan EA, Morrow JD, Hersh CP, O'Brien J, Crapo JD, Hansel NN, Criner G, Flenaugh EL, Conrad D, Casaburi R, Bowler RP, Hanania NA, et al. Returning incidentally discovered Hepatitis C RNA-seq results to COPDGene study participants. Npj Genomic Medicine. 8: 36. PMID 37903807 DOI: 10.1038/s41525-023-00379-4  0.319
2023 Zeng S, Luo G, Lynch DA, Bowler RP, Arjomandi M. Lung volumes differentiate the predominance of emphysema airway disease phenotype in early COPD: an observational study of the COPDGene cohort. Erj Open Research. 9. PMID 37727675 DOI: 10.1183/23120541.00289-2023  0.35
2023 Huffman JE, Nicolas J, Hahn J, Heath AS, Raffield LM, Yanek LR, Brody JA, Thibord F, Almasy L, Bartz TM, Bielak LF, Bowler RP, Carrasquilla GD, Chasman DI, Chen MH, et al. Whole genome analysis of plasma fibrinogen reveals population-differentiated genetic regulators with putative liver roles. Medrxiv : the Preprint Server For Health Sciences. PMID 37398003 DOI: 10.1101/2023.06.07.23291095  0.394
2023 Ngo D, Pratte KA, Flexeder C, Petersen H, Dang H, Ma Y, Keyes MJ, Gao Y, Deng S, Peterson BD, Farrell LA, Bhambhani VM, Palacios C, Quadir J, Gillenwater L, ... ... Bowler R, et al. Systemic Markers of Lung Function and FEV Decline across Diverse Cohorts. Annals of the American Thoracic Society. PMID 37351609 DOI: 10.1513/AnnalsATS.202210-857OC  0.536
2023 DiLillo KM, Norman KC, Freeman CM, Christenson SA, Alexis NE, Anderson WH, Barjaktarevic IZ, Barr RG, Comellas AP, Bleecker ER, Boucher RC, Couper DJ, Criner GJ, Doerschuk CM, Wells JM, ... ... Bowler RP, et al. A blood and bronchoalveolar lavage protein signature of rapid FEV decline in smoking-associated COPD. Scientific Reports. 13: 8228. PMID 37217548 DOI: 10.1038/s41598-023-32216-0  0.31
2023 Arjomandi M, Zeng S, Chen J, Bhatt SP, Abtin F, Barjaktarevic I, Barr RG, Bleecker ER, Buhr RG, Criner GJ, Comellas AP, Couper DJ, Curtis JL, Dransfield MT, Fortis S, ... ... Bowler RP, et al. Changes in Lung Volumes with Spirometric Disease Progression in COPD. Chronic Obstructive Pulmonary Diseases (Miami, Fla.). PMID 37199719 DOI: 10.15326/jcopdf.2022.0363  0.311
2023 Labaki WW, Gu T, Murray S, Curtis JL, Wells JM, Bhatt SP, Bon J, Diaz AA, Hersh CP, Wan ES, Kim V, Beaty TH, Hokanson JE, Bowler RP, Arenberg DA, et al. Causes of and Clinical Features Associated with Death in Tobacco Cigarette Users by Lung Function Impairment. American Journal of Respiratory and Critical Care Medicine. PMID 37159910 DOI: 10.1164/rccm.202210-1887OC  0.465
2022 LeMaster WB, Quibrera PM, Couper D, Tashkin DP, Bleecker ER, Doerschuk CM, Ortega VE, Cooper C, Han MK, Woodruff PG, O'Neal WK, Anderson WH, Alexis NE, Bowler RP, Barr RG, et al. Clinical implications of low absolute blood eosinophil count in the SPIROMICS COPD cohort. Chest. PMID 36343688 DOI: 10.1016/j.chest.2022.10.029  0.317
2022 Godbole S, Bowler RP. Metabolome Features of COPD: A Scoping Review. Metabolites. 12. PMID 35888745 DOI: 10.3390/metabo12070621  0.314
2022 Madapoosi SS, Cruickshank-Quinn C, Opron K, Erb-Downward JR, Begley LA, Li G, Barjaktarevic I, Barr RG, Comellas AP, Couper D, Cooper CB, Freeman C, Han M, Kaner RJ, Labaki W, ... ... Bowler RP, et al. Lung Microbiota and Metabolites Collectively Associate with Clinical Outcomes in Milder Stage COPD. American Journal of Respiratory and Critical Care Medicine. PMID 35536732 DOI: 10.1164/rccm.202110-2241OC  0.318
2021 Esther CR, O'Neal WK, Anderson WH, Kesimer M, Ceppe A, Doerschuk CM, Alexis NE, Hastie AT, Barr RG, Bowler RP, Wells JM, Oelsner EC, Comellas AP, Tesfaigzi Y, Kim V, et al. Identification of Sputum Biomarkers Predictive of Pulmonary Exacerbations in Chronic Obstructive Pulmonary Disease. Chest. PMID 34801592 DOI: 10.1016/j.chest.2021.10.049  0.31
2021 Yee N, Markovic D, Buhr RG, Fortis S, Arjomandi M, Couper D, Anderson WH, Paine R, Woodruff PG, Han MK, Martinez FJ, Barr RG, Wells JM, Ortega VE, Hoffman EA, ... ... Bowler RP, et al. Significance of FEV/FEV in recognition of early airway disease in smokers at risk of development of COPD: Analysis of the SPIROMICS cohort. Chest. PMID 34767825 DOI: 10.1016/j.chest.2021.10.046  0.34
2021 Yun JH, Lee C, Liu T, Liu S, Kim EY, Xu S, Curtis JL, Pinello L, Bowler RP, Silverman EK, Hersh CP, Zhou X. Hedgehog interacting protein-expressing lung fibroblasts suppress lymphocytic inflammation in mice. Jci Insight. PMID 34375314 DOI: 10.1172/jci.insight.144575  0.317
2021 Fawzy A, Woo H, Balasubramanian A, Barjaktarevic I, Barr RG, Bowler RP, Comellas AP, Cooper CB, Couper D, Criner GJ, Dransfield MT, Han MK, Hoffman EA, Kanner RE, Krishnan JA, et al. Polycythemia is Associated with Lower Incidence of Severe COPD Exacerbations in SPIROMICS Study. Chronic Obstructive Pulmonary Diseases (Miami, Fla.). PMID 34197703 DOI: 10.15326/jcopdf.2021.0216  0.3
2021 Wade RC, Simmons JP, Boueiz A, Gregory A, Wan ES, Regan EA, Bhatt SP, Han MK, Bowler RP, Crapo JD, Silverman EK, Washko GR, Dransfield MT, Wells JM. Pulmonary Artery Enlargement is Associated with Exacerbations and Mortality in Ever-Smokers with Preserved Ratio Impaired Spirometry (PRISm). American Journal of Respiratory and Critical Care Medicine. PMID 34014810 DOI: 10.1164/rccm.202103-0619LE  0.468
2021 Luehrs RE, Moreau KL, Pierce GL, Wamboldt F, Aloia M, Weinberger HD, Make B, Bowler RP, Crapo JD, Meschede K, Kozora E, Moser DJ, Hoth KF. Cognitive Performance is Lower Among Individuals with Overlap Syndrome than with COPD or Obstructive Sleep Apnea Alone: Role of Carotid Artery Stiffness. Journal of Applied Physiology (Bethesda, Md. : 1985). PMID 33982592 DOI: 10.1152/japplphysiol.00477.2020  0.457
2021 Oh AL, Mularski RA, Barjaktarevic I, Barr RG, Bowler RP, Comellas AP, Cooper CB, Criner GJ, Han MK, Hansel NN, Hoffman EA, Kanner RE, Krishnan JA, Paine R, Parekh TM, et al. Defining Resilience to Smoking Related Lung Disease: A Modified Delphi Approach from SPIROMICS. Annals of the American Thoracic Society. PMID 33631079 DOI: 10.1513/AnnalsATS.202006-757OC  0.35
2021 Opron K, Begley LA, Erb-Downward JR, Freeman C, Madapoosi S, Alexis NE, Barjaktarevic I, Graham Barr R, Bleecker ER, Bowler RP, Christenson SA, Comellas AP, Cooper CB, Couper DJ, Doerschuk CM, et al. Lung microbiota associations with clinical features of COPD in the SPIROMICS cohort. Npj Biofilms and Microbiomes. 7: 14. PMID 33547327 DOI: 10.1038/s41522-021-00185-9  0.346
2021 Serban KA, Pratte KA, Bowler RP. "Protein biomarkers for COPD outcomes". Chest. PMID 33434499 DOI: 10.1016/j.chest.2021.01.004  0.319
2020 Fortis S, Wan ES, Kunisaki K, Eyck PT, Ballas ZK, Bowler RP, Crapo JD, Hokanson JE, Wendt C, Silverman EK, Comellas AP. Increased mortality associated with frequent exacerbations in COPD patients with mild-to-moderate lung function impairment, and smokers with normal spirometry. Respiratory Medicine: X. 3. PMID 35911870 DOI: 10.1016/j.yrmex.2020.100025  0.521
2020 Dunican EM, Elicker BM, Henry T, Gierada DS, Schiebler ML, Anderson W, Barjaktarevic I, Barr RG, Bleecker ER, Boucher RC, Bowler RP, Christenson SA, Comellas A, Cooper CB, Couper D, et al. Mucus Plugs and Emphysema in the Pathophysiology of Airflow Obstruction and Hypoxemia in Smokers. American Journal of Respiratory and Critical Care Medicine. PMID 33180550 DOI: 10.1164/rccm.202006-2248OC  0.353
2020 Brunette AM, Warner K, Holm KE, Meschede K, Wamboldt FS, Kozora E, Moser DJ, Make BJ, Crapo JD, Moreau KL, Weinberger HD, Bowler R, Hoth KF. Daily Activities: The Impact of COPD and Cognitive Dysfunction. Archives of Clinical Neuropsychology : the Official Journal of the National Academy of Neuropsychologists. PMID 33103191 DOI: 10.1093/arclin/acaa090  0.491
2020 Billatos E, Ash SY, Duan F, Xu K, Romanoff J, Marques H, Moses E, Han MK, Regan EA, Bowler RP, Mason SE, Doyle TJ, San José Estépar R, Rosas IO, Ross JC, et al. Distinguishing smoking related lung disease phenotypes via imaging and molecular features. Chest. PMID 32946850 DOI: 10.1016/J.Chest.2020.08.2115  0.437
2020 Strand M, Austin E, Moll M, Pratte KA, Regan EA, Hayden LP, Bhatt SP, Boriek AM, Casaburi R, Silverman EK, Fortis S, Ruczinski I, Koegler H, Rossiter HB, Occhipinti M, ... ... Bowler RP, et al. A Risk Prediction Model for Mortality Among Smokers in the COPDGene® Study. Chronic Obstructive Pulmonary Diseases (Miami, Fla.). 7. PMID 32877963 DOI: 10.15326/Jcopdf.7.4.2020.0146  0.467
2020 Cooper CB, Paine R, Curtis JL, Kanner RE, Martinez CH, Meldrum CA, Bowler R, O'Neal W, Hoffman EA, Couper D, Quibrera M, Criner G, Dransfield MT, Han MK, Hansel NN, et al. Novel Respiratory Disability Score Predicts COPD Exacerbations and Mortality in the SPIROMICS Cohort. International Journal of Chronic Obstructive Pulmonary Disease. 15: 1887-1898. PMID 32821092 DOI: 10.2147/Copd.S250191  0.345
2020 Bon J, Nouraie SM, Smith KJ, Dransfield MT, McDonald ML, Hoffman EA, Newell JD, Comellas AP, Saha PK, Bowler RP, Regan EA. Lung-Specific Risk Factors Associated With Incident Hip Fracture in Current and Former Smokers. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 32754944 DOI: 10.1002/Jbmr.4103  0.332
2020 Schweitzer KS, Jinawath N, Yonescu R, Ni K, Rush N, Charoensawan V, Bronova I, Berdyshev E, Leach SM, Gillenwater LA, Bowler RP, Pearse DB, Griffin CA, Petrache I. IGSF3 mutation identified in patient with severe COPD alters cell function and motility. Jci Insight. PMID 32573489 DOI: 10.1172/Jci.Insight.138101  0.336
2020 Putcha N, Fawzy A, Matsui EC, Liu M, Bowler RP, Woodruff P, O'Neal WK, Comellas AP, Han MK, Dransfield M, Wells JM, Lugogo N, Gao L, Talbot CC, Hoffman E, et al. Clinical phenotypes of atopy and asthma in COPD: a meta-analysis of SPIROMICS and COPDGene. Chest. PMID 32450244 DOI: 10.1016/J.Chest.2020.04.069  0.312
2020 Raffield LM, Dang H, Pratte KA, Jacobson S, Gillenwater L, Ampleford E, Barjaktarevic I, Basta P, Clish CB, Comellas AP, Cornell E, Curtis JL, Doerschuk C, Durda P, Emson C, ... ... Bowler RP, et al. Comparison of Proteomic Assessment Methods in Multiple Cohort Studies. Proteomics. e1900278. PMID 32386347 DOI: 10.1002/Pmic.201900278  0.307
2020 Moll M, Qiao D, Regan EA, Hunninghake GM, Make BJ, Tal-Singer R, McGeachie M, Castaldi PJ, San Jose Estepar R, Washko G, Wells JM, LaFon D, Strand M, Bowler RP, Han MK, et al. Machine Learning and Prediction of All-Cause Mortality in Chronic Obstructive Pulmonary Disease. Chest. PMID 32353417 DOI: 10.1016/J.Chest.2020.02.079  0.527
2020 Hoth KF, Moreau KL, Weinberger HD, Holm KE, Meschede K, Crapo JD, Make BJ, Moser DJ, Kozora E, Bowler RP, Pierce GL, Ten Eyck P, Wamboldt FS. Carotid Artery Stiffness is Associated With Cognitive Performance in Former Smokers With and Without Chronic Obstructive Pulmonary Disease. Journal of the American Heart Association. e014862. PMID 32338117 DOI: 10.1161/Jaha.119.014862  0.571
2020 Mastej E, Gillenwater L, Zhuang Y, Pratte KA, Bowler RP, Kechris K. Identifying Protein-metabolite Networks Associated with COPD Phenotypes. Metabolites. 10. PMID 32218378 DOI: 10.3390/Metabo10040124  0.379
2020 Burkes RM, Ceppe AS, Doerschuk CM, Couper D, Hoffman EA, Comellas AP, Barr RG, Krishnan JA, Cooper C, Labaki WW, Ortega VE, Wells JM, Criner GJ, Woodruff PG, Bowler RP, et al. Associations between 25-hydroxy-vitamin D levels, lung function, and exacerbation outcomes in COPD: An analysis of the SPIROMICS cohort. Chest. PMID 31958447 DOI: 10.1016/J.Chest.2019.11.047  0.324
2020 Zhang WZ, Rice MC, Hoffman KL, Oromendia C, Barjaktarevic I, Wells JM, Hastie AT, Labaki WW, Cooper CB, Comellas AP, Criner GJ, Krishnan JA, Paine Iii R, Hansel NN, Bowler RP, et al. Association of urine mitochondrial DNA with clinical measures of COPD in the SPIROMICS cohort. Jci Insight. PMID 31895696 DOI: 10.1172/Jci.Insight.133984  0.326
2019 Barjaktarevic IZ, Buhr RG, Wang X, Hu S, Couper D, Anderson W, Kanner RE, Paine Iii R, Bhatt SP, Bhakta NR, Arjomandi M, Kaner RJ, Pirozzi CS, Curtis JL, O'Neal WK, ... ... Bowler R, et al. Clinical Significance of Bronchodilator Responsiveness Evaluated by Forced Vital Capacity in COPD: SPIROMICS Cohort Analysis. International Journal of Chronic Obstructive Pulmonary Disease. 14: 2927-2938. PMID 31908441 DOI: 10.2147/Copd.S220164  0.306
2019 LaFon DC, Bhatt SP, Labaki WW, Rahaghi FN, Moll M, Bowler RP, Regan EA, Make BJ, Crapo JD, San Jose Estepar R, Diaz AA, Silverman EK, Han MK, Hobbs B, Cho MH, et al. Pulmonary artery enlargement and mortality risk in moderate to severe COPD: results from COPDGene. The European Respiratory Journal. PMID 31772001 DOI: 10.1183/13993003.01812-2019  0.519
2019 Croghan A, Brunette A, Holm KE, Kozora E, Moser DJ, Wamboldt FS, Meschede K, Make BJ, Crapo JD, Weinberger HD, Moreau KL, Bowler RP, Hoth KF. Reduced Attention in Former Smokers with and without COPD. International Journal of Behavioral Medicine. PMID 31732904 DOI: 10.1007/S12529-019-09826-Y  0.525
2019 Young KA, Regan EA, Han MK, Lutz SM, Ragland M, Castaldi PJ, Washko GR, Cho MH, Strand M, Curran-Everett D, Beaty TH, Bowler RP, Wan ES, Lynch DA, Make BJ, et al. Subtypes of COPD Have Unique Distributions and Differential Risk of Mortality. Chronic Obstructive Pulmonary Diseases (Miami, Fla.). 6: 400-413. PMID 31710795 DOI: 10.15326/Jcopdf.6.5.2019.0150  0.564
2019 Lowe KE, Regan EA, Anzueto A, Austin E, Austin JHM, Beaty TH, Benos PV, Benway CJ, Bhatt SP, Bleecker ER, Bodduluri S, Bon J, Boriek AM, Boueiz AR, Bowler RP, et al. COPDGene 2019: Redefining the Diagnosis of Chronic Obstructive Pulmonary Disease. Chronic Obstructive Pulmonary Diseases (Miami, Fla.). 6: 384-399. PMID 31710793 DOI: 10.15326/Jcopdf.6.5.2019.0149  0.56
2019 Arjomandi M, Zeng S, Barjaktarevic I, Barr RG, Bleecker ER, Bowler RP, Buhr RG, Criner GJ, Comellas AP, Cooper CB, Couper DJ, Curtis JL, Dransfield MT, Han MK, Hansel NN, et al. Radiographic Lung Volumes Predict Progression to COPD in Smokers with Preserved Spirometry in SPIROMICS. The European Respiratory Journal. PMID 31439683 DOI: 10.1183/13993003.02214-2018  0.427
2019 Labaki WW, Gu T, Murray S, Curtis JL, Yeomans L, Bowler RP, Barr RG, Comellas AP, Hansel NN, Cooper CB, Barjaktarevic I, Kanner RE, Paine R, McDonald MN, Krishnan JA, et al. Serum amino acid concentrations and clinical outcomes in smokers: SPIROMICS metabolomics study. Scientific Reports. 9: 11367. PMID 31388056 DOI: 10.1038/S41598-019-47761-W  0.321
2019 Balasubramanian A, MacIntyre NR, Henderson RJ, Jensen RL, Kinney G, Stringer WW, Hersh CP, Bowler RP, Casaburi R, Han MK, Porszasz J, Barr RG, Make BJ, Wise RA, McCormack MC. Diffusing Capacity of Carbon Monoxide in Assessment of Chronic Obstructive Pulmonary Disease. Chest. PMID 31352035 DOI: 10.1016/J.Chest.2019.06.035  0.391
2019 Halper-Stromberg E, Gillenwater L, Cruickshank-Quinn C, O'Neal WK, Reisdorph N, Petrache I, Zhuang Y, Labaki WW, Curtis JL, Wells J, Rennard S, Pratte KA, Woodruff P, Stringer KA, Kechris K, ... Bowler RP, et al. Bronchoalveolar Lavage Fluid from COPD Patients Reveals More Compounds Associated with Disease than Matched Plasma. Metabolites. 9. PMID 31349744 DOI: 10.3390/Metabo9080157  0.411
2019 Regan EA, Lowe KE, Make BJ, Lynch DA, Kinney GL, Budoff MJ, Mao SS, Dyer D, Curtis JL, Bowler RP, Han MK, Beaty TH, Hokanson JE, Kern E, Humphries S, et al. Identifying Smoking-Related Disease on Lung Cancer Screening CT Scans: Increasing the Value. Chronic Obstructive Pulmonary Diseases (Miami, Fla.). 6: 233-245. PMID 31342730 DOI: 10.15326/Jcopdf.6.3.2018.0142  0.526
2019 Harmouche R, Ash SY, Putman RK, Hunninghake GM, San Jose Estepar R, Martinez FJ, Choi AM, Lynch DA, Hatabu H, Han MK, Bowler RP, Kalhan R, Rosas IO, Washko GR, San Jose Estepar R, et al. Objectively Measured Chronic Lung Injury on Chest Computed Tomography. Chest. PMID 31233744 DOI: 10.1016/J.Chest.2019.05.020  0.389
2019 Maselli DJ, Bhatt SP, Anzueto A, Bowler RP, DeMeo DL, Diaz AA, Dransfield MT, Fawzy A, Foreman MG, Hanania NA, Hersh CP, Kim V, Kinney GL, Putcha N, Wan ES, et al. Clinical epidemiology of COPD - Insights from 10 years of the COPDGene study. Chest. PMID 31154041 DOI: 10.1016/J.Chest.2019.04.135  0.398
2019 Bowler R, Allinder M, Jacobson S, Miller A, Miller B, Tal-Singer R, Locantore N. Real-world use of rescue inhaler sensors, electronic symptom questionnaires and physical activity monitors in COPD. Bmj Open Respiratory Research. 6: e000350. PMID 30956796 DOI: 10.1136/Bmjresp-2018-000350  0.37
2019 Oelsner EC, Ortega VE, Smith BM, Nguyen JN, Manichaikul AW, Hoffman EA, Guo X, Taylor KD, Woodruff PG, Couper DJ, Hansel NN, Martinez FJ, Paine Iii R, Han MK, Cooper C, ... ... Bowler R, et al. A Genetic Risk Score Associated with COPD Susceptibility and Lung Structure on Computed Tomography. American Journal of Respiratory and Critical Care Medicine. PMID 30925230 DOI: 10.1164/Rccm.201812-2355Oc  0.405
2019 Ragland M, Benway CJ, Lutz SM, Bowler RP, Hecker J, Hokanson JE, Crapo JD, Castaldi PJ, DeMeo DL, Hersh CP, Hobbs BD, Lange C, Beaty TH, Cho MH, Silverman EK. Genetic Advances in COPD: Insights from COPDGene. American Journal of Respiratory and Critical Care Medicine. PMID 30908940 DOI: 10.1164/Rccm.201808-1455So  0.521
2019 Rao DM, Phan DT, Choo MJ, Weaver MR, Oberley-Deegan RE, Bowler RP, Gally F. Impact of fatty acid binding protein 5-deficiency on COPD exacerbations and cigarette smoke-induced inflammatory response to bacterial infection. Clinical and Translational Medicine. 8: 7. PMID 30877402 DOI: 10.1186/S40169-019-0227-8  0.403
2019 Regan EA, Hersh CP, Castaldi PJ, DeMeo DL, Silverman EK, Crapo JD, Bowler RP. Omics and the Search for Blood Biomarkers in COPD: Insights from COPDGene. American Journal of Respiratory Cell and Molecular Biology. PMID 30874442 DOI: 10.1165/Rcmb.2018-0245Ps  0.53
2019 Garudadri S, Woodruff PG, Han MK, Curtis JL, Barr RG, Bleecker ER, Bowler RP, Comellas A, Cooper CB, Criner G, Dransfield MT, Hansel NN, Paine R, Krishnan JA, Peters SP, et al. Systemic markers of inflammation in smokers with symptoms despite preserved spirometry in SPIROMICS. Chest. PMID 30684474 DOI: 10.1016/J.Chest.2018.12.022  0.374
2019 Wells JM, Arenberg DA, Barjaktarevic I, Bhatt SP, Bowler RP, Christenson SA, Couper DJ, Dransfield MT, Han MK, Hoffman EA, Kaner RJ, Kim V, Kleerup E, Martinez FJ, Moore WC, et al. Safety and Tolerability of Comprehensive Research Bronchoscopy in COPD: Results from the SPIROMICS Bronchoscopy Sub-Study. Annals of the American Thoracic Society. PMID 30653926 DOI: 10.1513/Annalsats.201807-441Oc  0.402
2019 Arjomandi M, Zeng S, Barjaktarevic I, Barr RG, Bleecker ER, Bowler RP, Buhr RG, Criner GJ, Comellas AP, Cooper CB, Couper DJ, Curtis JL, Dransfield MT, Han MK, Hansel NN, et al. Lung volume comparisons between spirometry and computed tomography in SPIROMICS European Respiratory Journal. DOI: 10.1183/13993003.Congress-2019.Pa779  0.307
2019 Labaki W, Gu T, Murray S, Curtis J, Soler X, Bhatt S, Bon J, Beaty T, Hokanson J, Curran-Everett D, Lowe K, Bowler R, Make B, Regan E, Martinez F, et al. Health status impact on mortality and lung function decline in COPDGene smokers European Respiratory Journal. DOI: 10.1183/13993003.Congress-2019.Oa508  0.504
2018 Koike K, Berdyshev EV, Bowler RP, Scruggs AK, Cao D, Schweitzer KS, Serban KA, Petrache I. Bioactive Sphingolipids in the Pathogenesis of Chronic Obstructive Pulmonary Disease. Annals of the American Thoracic Society. 15: S249-S252. PMID 30759004 DOI: 10.1513/Annalsats.201809-592Mg  0.442
2018 Fawzy A, Putcha N, Aaron CP, Bowler RP, Comellas AP, Cooper CB, Dransfield MT, Han MK, Hoffman EA, Kanner RE, Krishnan JA, Labaki WW, Paine R, Paulin LM, Peters SP, et al. Aspirin Use and Respiratory Morbidity in COPD: a Propensity Score Matched Analysis in SPIROMICS. Chest. PMID 30593776 DOI: 10.1016/J.Chest.2018.11.028  0.35
2018 Shaddox E, Peterson CB, Stingo FC, Hanania NA, Cruickshank-Quinn C, Kechris K, Bowler R, Vannucci M. Bayesian inference of networks across multiple sample groups and data types. Biostatistics (Oxford, England). PMID 30590505 DOI: 10.1093/Biostatistics/Kxy078  0.303
2018 Cruickshank-Quinn CI, Jacobson S, Hughes G, Powell RL, Petrache I, Kechris K, Bowler R, Reisdorph N. Metabolomics and transcriptomics pathway approach reveals outcome-specific perturbations in COPD. Scientific Reports. 8: 17132. PMID 30459441 DOI: 10.1038/S41598-018-35372-W  0.395
2018 Wells JM, Parker MM, Oster RA, Bowler RP, Dransfield MT, Bhatt SP, Cho MH, Kim V, Curtis JL, Martinez FJ, Paine R, O'Neal W, Labaki WW, Kaner RJ, Barjaktarevic I, et al. Elevated circulating MMP-9 is linked to increased COPD exacerbation risk in SPIROMICS and COPDGene. Jci Insight. 3. PMID 30429371 DOI: 10.1172/Jci.Insight.123614  0.559
2018 Christenson SA, van den Berge M, Faiz A, Imkamp K, Bhakta N, Bonser LR, Zlock LT, Barjaktarevic IZ, Barr RG, Bleecker ER, Boucher RC, Bowler RP, Comellas AP, Curtis JL, Han MK, et al. An airway epithelial IL-17A response signature identifies a steroid-unresponsive COPD patient subgroup. The Journal of Clinical Investigation. PMID 30383540 DOI: 10.1172/Jci121087  0.417
2018 Suh YJ, McDonald MN, Washko GR, Carolan BJ, Bowler RP, Lynch DA, Kinney GL, Bon JM, Cho MH, Crapo JD, Regan EA. Lung, Fat and Bone: Increased Adiponectin Associates with the Combination of Smoking-Related Lung Disease and Osteoporosis. Chronic Obstructive Pulmonary Diseases (Miami, Fla.). 5: 134-143. PMID 30374451 DOI: 10.15326/jcopdf.5.2.2016.0174  0.523
2018 Garcia AM, Allawzi A, Tatman P, Hernandez-Lagunas L, Swain K, Mouradian G, Bowler RP, Karimpour-Fard A, Sucharov CC, Nozik-Grayck E. The R213G polymorphism in SOD3 protects against bleomycin-induced inflammation and attenuates induction of pro-inflammatory pathways. Physiological Genomics. PMID 30004839 DOI: 10.1152/Physiolgenomics.00053.2018  0.309
2018 Labaki WW, Xia M, Murray S, Curtis JL, Barr RG, Bhatt SP, Bleecker ER, Hansel NN, Cooper CB, Dransfield MT, Wells JM, Hoffman EA, Kanner RE, Paine R, Ortega VE, ... ... Bowler RP, et al. NT-proBNP in stable COPD and future exacerbation risk: Analysis of the SPIROMICS cohort. Respiratory Medicine. 140: 87-93. PMID 29957287 DOI: 10.1016/J.Rmed.2018.06.005  0.302
2018 Ash SY, Harmouche R, Ross JC, Diaz AA, Rahaghi FN, Sanchez-Ferrero GV, Putman RK, Hunninghake GM, Onieva JO, Martinez FJ, Choi AM, Bowler RP, Lynch DA, Hatabu H, Bhatt SP, et al. Interstitial Features at Chest CT Enhance the Deleterious Effects of Emphysema in the COPDGene Cohort. Radiology. 172688. PMID 29869957 DOI: 10.1148/Radiol.2018172688  0.378
2018 Lynch DA, Moore CM, Wilson C, Nevrekar D, Jennermann T, Humphries SM, Austin JHM, Grenier PA, Kauczor HU, Han MK, Regan EA, Make BJ, Bowler RP, Beaty TH, Curran-Everett D, et al. CT-based Visual Classification of Emphysema: Association with Mortality in the COPDGene Study. Radiology. 172294. PMID 29762095 DOI: 10.1148/Radiol.2018172294  0.517
2018 Putcha N, Paul GG, Azar A, Wise RA, O'Neal WK, Dransfield MT, Woodruff PG, Curtis JL, Comellas AP, Drummond MB, Lambert AA, Paulin LM, Fawzy A, Kanner RE, Paine R, ... ... Bowler RP, et al. Lower serum IgA is associated with COPD exacerbation risk in SPIROMICS. Plos One. 13: e0194924. PMID 29649230 DOI: 10.1371/Journal.Pone.0194924  0.309
2018 Diaz AA, Martinez CH, Harmouche R, Young TP, McDonald ML, Ross JC, Han ML, Bowler R, Make B, Regan EA, Silverman EK, Crapo J, Boriek AM, Kinney GL, Hokanson JE, et al. Pectoralis muscle area and mortality in smokers without airflow obstruction. Respiratory Research. 19: 62. PMID 29636050 DOI: 10.1186/S12931-018-0771-6  0.478
2018 Morris MA, Jacobson SR, Kinney GL, Tashkin DP, Woodruff PG, Hoffman EA, Kanner RE, Cooper CB, Drummond MB, Barr RG, Oelsner EC, Make BJ, Han MK, Hansel NN, O'Neal WK, ... Bowler RP, et al. Marijuana Use Associations with Pulmonary Symptoms and Function in Tobacco Smokers Enrolled in the Subpopulations and Intermediate Outcome Measures in COPD Study (SPIROMICS). Chronic Obstructive Pulmonary Diseases (Miami, Fla.). 5: 46-56. PMID 29629404 DOI: 10.15326/Jcopdf.5.1.2017.0141  0.406
2018 Sherlock LG, Trumpie A, Hernandez-Lagunas L, McKenna S, Fisher S, Bowler R, Wright CJ, Delaney C, Nozik-Grayck E. Redistribution of Extracellular Superoxide Dismutase Causes Neonatal Pulmonary Vascular Remodeling and PH but Protects Against Experimental Bronchopulmonary Dysplasia. Antioxidants (Basel, Switzerland). 7. PMID 29538340 DOI: 10.3390/Antiox7030042  0.386
2018 Rho JY, Lynch DA, Suh YJ, Nah JW, Zach JA, Schroeder JD, Cox CW, Bowler RP, Fenster BE, Dransfield MT, Wells JM, Hokanson JE, Curran-Everett D, Williams A, Han MK, et al. CT measurements of central pulmonary vasculature as predictors of severe exacerbation in COPD. Medicine. 97: e9542. PMID 29504975 DOI: 10.1097/Md.0000000000009542  0.546
2018 Carr LL, Jacobson S, Lynch DA, Foreman MG, Flenaugh EL, Hersh CP, Sciurba FC, Wilson DO, Sieren JC, Mulhall P, Kim V, Kinsey CM, Bowler RP. Features of Chronic Obstructive Pulmonary Disease as Predictors of Lung Cancer. Chest. PMID 29452098 DOI: 10.1016/J.Chest.2018.01.049  0.429
2018 Ash SY, Harmouche R, Putman RK, Ross JC, Martinez FJ, Choi AM, Bowler RP, Regan EA, Curtis JL, Han MK, Boucher RC, O'Neal WK, Hatabu H, Lynch DA, Rosas IO, et al. Association between acute respiratory disease events and thepromoter polymorphism in smokers. Thorax. PMID 29440587 DOI: 10.1136/Thoraxjnl-2017-211208  0.356
2018 Fawzy A, Putcha N, Paulin LM, Aaron CP, Labaki WW, Han MK, Wise RA, Kanner RE, Bowler RP, Barr RG, Hansel NN. Association of thrombocytosis with COPD morbidity: the SPIROMICS and COPDGene cohorts. Respiratory Research. 19: 20. PMID 29373977 DOI: 10.1186/S12931-018-0717-Z  0.377
2018 Nambu A, Zach J, Kim SS, Jin G, Schroeder J, Kim YI, Bowler R, Lynch DA. Significance of Low-Attenuation Cluster Analysis on Quantitative CT in the Evaluation of Chronic Obstructive Pulmonary Disease. Korean Journal of Radiology. 19: 139-146. PMID 29354010 DOI: 10.3348/Kjr.2018.19.1.139  0.39
2018 Labaki W, Gu T, Murray S, Curtis J, Bowler R, Barr RG, Hoffman E, Comellas A, Hansel N, Cooper C, Kanner R, Paine R, Criner G, Dransfield M, Mcdonald M, et al. Altered serum metabolomics in COPD: analysis of the SPIROMICS cohort European Respiratory Journal. 52. DOI: 10.1183/13993003.Congress-2018.Pa580  0.345
2018 Wells JM, Parker MM, Oster RA, Bowler RP, Dransfield MT, Bhatt SP, Cho MH, Kim V, Curtis JL, Martinez FJ, Paine R, O'Neal W, Labaki WW, Kaner RJ, Barjaktarevic I, et al. Elevated circulating MMP-9 is associated with increased exacerbation risk in COPD: results from SPIROMICS and COPDGene European Respiratory Journal. DOI: 10.1183/13993003.Congress-2018.Pa3857  0.323
2018 Kady M, Christenson S, Stolberg V, Bates M, Labaki W, Alexis N, Barjaktarevic I, Barr G, Bleecker E, Boucher R, Bowler R, Cooper C, Couper D, Doerschuk C, Han M, et al. Lung dendritic cells correlate to small airway abnormality & lung CD4+ T cells: SPIROMICS bronchoscopy study European Respiratory Journal. 52. DOI: 10.1183/13993003.Congress-2018.Oa4925  0.352
2018 Buhr R, Barjaktarevic I, Wang X, Dolezal B, Flynn M, Couper D, Anderson W, Paine R, Kaner R, Curtis J, O'Neal W, Woodruff P, Postow L, Han M, Martinez F, ... ... Bowler R, et al. Airflow obstruction which corrects post-bronchodilator as a predictor of future development of COPD European Respiratory Journal. DOI: 10.1183/13993003.Congress-2018.Oa2153  0.367
2018 Flynn M, Buhr R, Wang X, Lemaster W, Dolezal B, Couper D, Anderson W, Kanner R, Paine R, Kaner R, Curtis J, O'Neal W, Woodruff P, Postow L, Han M, ... ... Bowler R, et al. Reduced FEV3/FVC identifies smokers at risk of developing COPD in the SPIROMICS cohort European Respiratory Journal. DOI: 10.1183/13993003.Congress-2018.Oa2152  0.372
2018 Luehrs RE, Moreau KL, Aloia M, Weinberger HD, Make B, Bowler R, Crapo JD, Wamboldt F, Hoth KF, Pierce GL. Abstract P133: Obstructive Sleep Apnea May Exacerbate Carotid Artery Stiffness in Individuals With Chronic Obstructive Pulmonary Disease Hypertension. 72. DOI: 10.1161/Hyp.72.Suppl_1.P133  0.513
2017 Halper-Stromberg E, Yun JH, Parker MM, Tal Singer R, Gaggar A, Silverman EK, Leach S, Bowler RP, Castaldi PJ. Systemic Markers of Adaptive and Innate Immunity are Associated with COPD Severity and Spirometric Disease Progression. American Journal of Respiratory Cell and Molecular Biology. PMID 29206476 DOI: 10.1165/Rcmb.2017-0373Oc  0.376
2017 Bowler RP, Wendt CH, Fessler MB, Foster MW, Kelly RS, Lasky-Su J, Rogers AJ, Stringer KA, Winston BW. New Strategies and Challenges in Lung Proteomics and Metabolomics. An Official American Thoracic Society Workshop Report. Annals of the American Thoracic Society. 14: 1721-1743. PMID 29192815 DOI: 10.1513/Annalsats.201710-770Ws  0.332
2017 Martinez CH, Diaz AA, Meldrum CA, McDonald MN, Murray S, Kinney GL, Hokanson JE, Curtis JL, Bowler RP, Han MK, Washko GR, Regan EA. Handgrip Strength in Chronic Obstructive Pulmonary Disease. Associations with Acute Exacerbations and Body Composition. Annals of the American Thoracic Society. 14: 1638-1645. PMID 29090990 DOI: 10.1513/Annalsats.201610-821Oc  0.413
2017 Bradford E, Jacobson S, Varasteh J, Comellas AP, Woodruff P, O'Neal W, DeMeo DL, Li X, Kim V, Cho M, Castaldi PJ, Hersh C, Silverman EK, Crapo JD, Kechris K, ... Bowler RP, et al. The value of blood cytokines and chemokines in assessing COPD. Respiratory Research. 18: 180. PMID 29065892 DOI: 10.1186/S12931-017-0662-2  0.568
2017 Reinhold D, Morrow JD, Jacobson S, Hu J, Ringel B, Seibold MA, Hersh CP, Kechris KJ, Bowler RP. Meta-analysis of peripheral blood gene expression modules for COPD phenotypes. Plos One. 12: e0185682. PMID 29016655 DOI: 10.1371/Journal.Pone.0185682  0.377
2017 Hansel NN, Paulin LM, Gassett AJ, Peng RD, Alexis N, Fan VS, Bleecker E, Bowler R, Comellas AP, Dransfield M, Han MK, Kim V, Krishnan JA, Pirozzi C, Cooper CB, et al. Design of the Subpopulations and Intermediate Outcome Measures in COPD (SPIROMICS) AIR Study. Bmj Open Respiratory Research. 4: e000186. PMID 28948026 DOI: 10.1136/Bmjresp-2017-000186  0.348
2017 Boueiz A, Chang Y, Cho MH, Washko GR, San José Estépar R, Bowler RP, Crapo JD, DeMeo DL, Dy JG, Silverman EK, Castaldi PJ. Lobar emphysema distribution is associated with 5-year radiologic disease progression. Chest. PMID 28943279 DOI: 10.1016/J.Chest.2017.09.022  0.515
2017 Gaurav R, Varasteh JT, Weaver MR, Jacobson SR, Hernandez-Lagunas L, Liu Q, Nozik-Grayck E, Chu HW, Alam R, Nordestgaard BG, Kobylecki CJ, Afzal S, Chupp GL, Bowler RP. The R213G polymorphism in SOD3 protects against allergic airway inflammation. Jci Insight. 2. PMID 28878123 DOI: 10.1172/Jci.Insight.95072  0.347
2017 Brunette AM, Holm KE, Wamboldt FS, Kozora E, Moser DJ, Make BJ, Crapo JD, Meschede K, Weinberger HD, Moreau KL, Bowler RP, Hoth KF. Subjective cognitive complaints and neuropsychological performance in former smokers with and without chronic obstructive pulmonary disease. Journal of Clinical and Experimental Neuropsychology. 1-12. PMID 28766459 DOI: 10.1080/13803395.2017.1356912  0.474
2017 Cruickshank-Quinn C, Powell R, Jacobson S, Kechris K, Bowler RP, Petrache I, Reisdorph N. Metabolomic similarities between bronchoalveolar lavage fluid and plasma in humans and mice. Scientific Reports. 7: 5108. PMID 28698669 DOI: 10.1038/S41598-017-05374-1  0.318
2017 Han MK, Quibrera PM, Carretta EE, Barr RG, Bleecker ER, Bowler RP, Cooper CB, Comellas A, Couper DJ, Curtis JL, Criner G, Dransfield MT, Hansel NN, Hoffman EA, Kanner RE, et al. Frequency of exacerbations in patients with chronic obstructive pulmonary disease: an analysis of the SPIROMICS cohort. The Lancet. Respiratory Medicine. PMID 28668356 DOI: 10.1016/S2213-2600(17)30207-2  0.406
2017 Castaldi PJ, Benet M, Petersen H, Rafaels N, Finigan J, Paoletti M, Marike Boezen H, Vonk JM, Bowler R, Pistolesi M, Puhan MA, Anto J, Wauters E, Lambrechts D, Janssens W, et al. Do COPD subtypes really exist? COPD heterogeneity and clustering in 10 independent cohorts. Thorax. PMID 28637835 DOI: 10.1136/Thoraxjnl-2016-209846  0.512
2017 Zemans RL, Jacobson S, Keene J, Kechris K, Miller BE, Tal-Singer R, Bowler RP. Multiple biomarkers predict disease severity, progression and mortality in COPD. Respiratory Research. 18: 117. PMID 28610627 DOI: 10.1186/S12931-017-0597-7  0.356
2017 Miller MA, Danhorn T, Cruickshank-Quinn CI, Leach SM, Jacobson S, Strand MJ, Reisdorph NA, Bowler RP, Petrache I, Kechris K. Gene and metabolite time-course response to cigarette smoking in mouse lung and plasma. Plos One. 12: e0178281. PMID 28575117 DOI: 10.1371/Journal.Pone.0178281  0.394
2017 Martinez CH, Murray S, Barr RG, Bleecker E, Bowler RP, Christenson SA, Comellas AP, Cooper CB, Couper D, Criner GJ, Curtis JL, Dransfield MT, Hansel NN, Hoffman EA, Kanner RE, et al. Respiratory Symptoms Items from the COPD Assessment Test Identify Ever-Smokers with Preserved Lung Function at Higher Risk for Poor Respiratory Outcomes. An Analysis of the Subpopulations and Intermediate Outcome Measures in COPD Study Cohort. Annals of the American Thoracic Society. 14: 636-642. PMID 28459622 DOI: 10.1513/Annalsats.201610-815Oc  0.407
2017 Bihlet AR, Karsdal MA, Sand JM, Leeming DJ, Roberts M, White W, Bowler R. Biomarkers of extracellular matrix turnover are associated with emphysema and eosinophilic-bronchitis in COPD. Respiratory Research. 18: 22. PMID 28103932 DOI: 10.1186/S12931-017-0509-X  0.425
2017 Regan E, Make B, Kinney G, Budoff M, Dyer D, Curtis J, Bowler R, Han M, Beaty T, Hokanson J, Kern E, Lynch D, Van Beek E, Silverman E, Crapo J, et al. MA05.07 Identifying Comorbid Disease on Chest CT Scans in a Lung Cancer Screening-Eligible Cohort Journal of Thoracic Oncology. 12: S367-S368. DOI: 10.1016/J.Jtho.2016.11.411  0.498
2017 Grayck EN, Elajaili H, Allawzi A, Hernandez-Lagunas L, Nguyen K, El Kasmi K, Sherlock L, Wright C, Gaurav R, Bowler R, Karimpour-fard A, Sucharov C. The SOD3 R213G Polymorphism Promotes Resolution of Innate Immune Activation and Blocks Induction of miR29b in Bleomycin Induced Lung Inflammation and Fibrosis Free Radical Biology and Medicine. 112: 203-204. DOI: 10.1016/J.Freeradbiomed.2017.10.321  0.316
2016 Washko GR, Kinney GL, Ross JC, San José Estépar R, Han MK, Dransfield MT, Kim V, Hatabu H, Come CE, Bowler RP, Silverman EK, Crapo J, Lynch DA, Hokanson J, Diaz AA, et al. Lung Mass in Smokers. Academic Radiology. PMID 27940230 DOI: 10.1016/J.Acra.2016.10.011  0.553
2016 Lu Q, Jin C, Sun J, Bowler R, Kechris K, Kaminski N, Zhao H. Post-GWAS Prioritization Through Data Integration Provides Novel Insights on Chronic Obstructive Pulmonary Disease. Statistics in Biosciences. 2016: 1-17. PMID 27812370 DOI: 10.1007/S12561-016-9151-2  0.41
2016 Mouradian GC, Gaurav R, Pugliese S, El Kasmi K, Hartman B, Hernandez-Lagunas L, Stenmark K, Bowler RP, Nozik-Grayck E. SOD3 R213G SNP Blocks Murine Bleomycin-induced Fibrosis and Promotes Resolution of Inflammation. American Journal of Respiratory Cell and Molecular Biology. PMID 27805412 DOI: 10.1165/Rcmb.2016-0153Oc  0.371
2016 Kinney GL, Baker EH, Klein OL, Black-Shinn JL, Wan ES, Make B, Regan E, Bowler RP, Lutz SM, Young KA, Duca LM, Washko GR, Silverman EK, Crapo JD, Hokanson JE. Pulmonary Predictors of Incident Diabetes in Smokers. Chronic Obstructive Pulmonary Diseases (Miami, Fla.). 3: 739-747. PMID 27795984 DOI: 10.15326/Jcopdf.3.4.2016.0137  0.483
2016 Martinez FJ, Mannino D, Leidy NK, Malley KG, Bacci ED, Barr RG, Bowler RP, Han MK, Houfek JF, Make B, Meldrum CA, Rennard S, Thomashow B, Walsh J, Yawn BP, et al. A New Approach for Identifying Patients with Undiagnosed Chronic Obstructive Pulmonary Disease. American Journal of Respiratory and Critical Care Medicine. PMID 27783539 DOI: 10.1164/Rccm.201603-0622Oc  0.382
2016 Nambu A, Zach J, Schroeder J, Jin G, Kim SS, Kim YI, Schnell C, Bowler R, Lynch DA. Quantitative computed tomography measurements to evaluate airway disease in chronic obstructive pulmonary disease: Relationship to physiological measurements, clinical index and visual assessment of airway disease. European Journal of Radiology. 85: 2144-2151. PMID 27776670 DOI: 10.1016/J.Ejrad.2016.09.010  0.408
2016 Boueiz A, Lutz SM, Cho MH, Hersh CP, Bowler RP, Washko GR, Halper-Stromberg E, Bakke P, Gulsvik A, Laird NM, Beaty TH, Coxson HO, Crapo JD, Silverman EK, Castaldi PJ, et al. Genome-Wide Association Study of the Genetic Determinants of Emphysema Distribution. American Journal of Respiratory and Critical Care Medicine. PMID 27669027 DOI: 10.1164/Rccm.201605-0997Oc  0.503
2016 Keene JD, Jacobson S, Kechris K, Kinney GL, Foreman MG, Doerschuk CM, Make BJ, Curtis JL, Rennard SI, Barr RG, Bleecker ER, Kanner RE, Kleerup EC, Hansel NN, Woodruff PG, ... ... Bowler RP, et al. Biomarkers Predictive of Exacerbations in the SPIROMICS and COPDGene Cohorts. American Journal of Respiratory and Critical Care Medicine. PMID 27579823 DOI: 10.1164/Rccm.201607-1330Oc  0.335
2016 Dransfield MT, Kunisaki KM, Strand MJ, Anzueto A, Bhatt SP, Bowler RP, Criner GJ, Curtis JL, Hanania NA, Nath H, Putcha N, Roark SE, Wan ES, Washko GR, Wells JM, et al. Acute Exacerbations and Lung Function Loss in Smokers With and Without COPD. American Journal of Respiratory and Critical Care Medicine. PMID 27556408 DOI: 10.1164/Rccm.201605-1014Oc  0.424
2016 Sun W, Kechris K, Jacobson S, Drummond MB, Hawkins GA, Yang J, Chen TH, Quibrera PM, Anderson W, Barr RG, Basta PV, Bleecker ER, Beaty T, Casaburi R, Castaldi P, ... ... Bowler RP, et al. Common Genetic Polymorphisms Influence Blood Biomarker Measurements in COPD. Plos Genetics. 12: e1006011. PMID 27532455 DOI: 10.1371/Journal.Pgen.1006011  0.529
2016 Nozik-Grayck E, Woods C, Stearman RS, Venkataraman S, Ferguson BS, Swain K, Bowler RP, Geraci MW, Ihida-Stansbury K, Stenmark KR, McKinsey TA, Domann FE. Histone deacetylation contributes to low extracellular superoxide dismutase expression in human idiopathic pulmonary arterial hypertension. American Journal of Physiology. Lung Cellular and Molecular Physiology. ajplung.00263.2015. PMID 27233998 DOI: 10.1152/Ajplung.00263.2015  0.323
2016 Silver JS, Kearley J, Copenhaver AM, Sanden C, Mori M, Yu L, Pritchard GH, Berlin AA, Hunter CA, Bowler R, Erjefalt JS, Kolbeck R, Humbles AA. Inflammatory triggers associated with exacerbations of COPD orchestrate plasticity of group 2 innate lymphoid cells in the lungs. Nature Immunology. PMID 27111143 DOI: 10.1038/Ni.3443  0.325
2016 Bahmed K, Messier EM, Zhou W, Tuder RM, Freed CR, Chu HW, Kelsen SG, Bowler RP, Mason RJ, Kosmider B. DJ-1 Modulates Nrf2-mediated Protection in Human Primary Alveolar Type II Cells in Smokers. American Journal of Respiratory Cell and Molecular Biology. PMID 27093578 DOI: 10.1165/Rcmb.2015-0304Oc  0.373
2016 Putcha N, Barr RG, Han MK, Woodruff PG, Bleecker ER, Kanner RE, Martinez FJ, Smith BM, Tashkin DP, Bowler RP, Eisner MD, Rennard SI, Wise RA, Hansel NN. Understanding the impact of second-hand smoke exposure on clinical outcomes in participants with COPD in the SPIROMICS cohort. Thorax. PMID 26962015 DOI: 10.1136/Thoraxjnl-2015-207487  0.376
2016 Bhatt SP, Soler X, Wang X, Murray S, Anzueto AR, Beaty TH, Boriek AM, Casaburi R, Criner GJ, Diaz AA, Dransfield MT, Curran-Everett D, Galbán CJ, Hoffman EA, Hogg JC, ... ... Bowler RP, et al. Association Between Functional Small Airways Disease and FEV1 Decline in COPD. American Journal of Respiratory and Critical Care Medicine. PMID 26808615 DOI: 10.1164/Rccm.201511-2219Oc  0.566
2016 Chang Y, Glass K, Liu YY, Silverman EK, Crapo JD, Tal-Singer R, Bowler R, Dy J, Cho M, Castaldi P. COPD subtypes identified by network-based clustering of blood gene expression. Genomics. PMID 26773458 DOI: 10.1016/J.Ygeno.2016.01.004  0.532
2016 Smith B, Hoffman E, Bleecker E, Bowler R, Cooper C, Couper D, Comellas A, Dransfield M, MeiLan H, Hansel N, Krishnan J, Martinez F, Paine R, Rennard S, Woodruff P, et al. LATE-BREAKING ABSTRACT: A large airway phenotype among symptomatic smokers with preserved pulmonary function: The subpopulations and intermediate outcome measures in COPD study (SPIROMICS) European Respiratory Journal. 48. DOI: 10.1183/13993003.Congress-2016.Pa3829  0.442
2016 Martinez C, Murray S, Quibrera M, Woodruff P, Barr G, Cooper C, Bowler R, Bleecker E, Comellas A, Christenson S, Couper D, Curtis J, Gouskova N, Criner G, Hansel N, et al. LATE-BREAKING ABSTRACT: Five items from the CAT questionnaire identify smokers with preserved lung function at higher risk for poor respiratory outcomes: An analysis of the SPIROMICS cohort European Respiratory Journal. 48. DOI: 10.1183/13993003.Congress-2016.Pa3675  0.355
2016 Hanson C, Sayles H, Nordgren T, Bowler R. Fish intake and pulmonary outcomes in COPDGene European Respiratory Journal. 48. DOI: 10.1183/13993003.Congress-2016.Pa1144  0.346
2016 Cascio CL, Bleecker E, Christenson S, Couper D, Curtis J, Hansel N, Hoffman E, Kaner R, Kleerup E, Lazarus S, Martinez F, Paine R, Rennard S, Bowler R, Krishnan J, et al. LATE-BREAKING ABSTRACT: Activity limitation and exacerbations in smokers with emphysema on CT but preserved pulmonary function. SPIROMICS European Respiratory Journal. 48. DOI: 10.1183/13993003.Congress-2016.Oa1479  0.394
2016 Swain K, Mouradian G, Gaurav R, Pugliese S, Hernandez-Lagunas A, El Kasmi K, Karimpour-Fard A, Bowler R, Sucharov C, Nozik-Grayck E. The R213G Polymorphism in SOD3 Protects Early Bleomycin-Induced Pulmonary Inflammation and Attenuates Induction of Genes Involved in Agranulocyte/granulocyte Adhesion and Diapedesis Free Radical Biology and Medicine. 100: S60-S61. DOI: 10.1016/J.Freeradbiomed.2016.10.159  0.397
2016 Shaddox E, Stingo FC, Peterson CB, Jacobson S, Cruickshank-Quinn C, Kechris K, Bowler R, Vannucci M. A Bayesian Approach for Learning Gene Networks Underlying Disease Severity in COPD Statistics in Biosciences. 10: 59-85. DOI: 10.1007/S12561-016-9176-6  0.308
2015 Mishra R, Foster D, Vasu VT, Thaikoottathil JV, Kosmider B, Chu HW, Bowler RP, Finigan JH. Cigarette Smoke Induces HER2 Dependent Changes in Epithelial Permeability. American Journal of Respiratory Cell and Molecular Biology. PMID 26600084 DOI: 10.1165/Rcmb.2014-0437Oc  0.371
2015 Fenster BE, Holm KE, Weinberger HD, Moreau KL, Meschede K, Crapo JD, Make BJ, Bowler R, Wamboldt FS, Hoth KF. Right ventricular diastolic function and exercise capacity in COPD. Respiratory Medicine. 109: 1287-92. PMID 26371994 DOI: 10.1016/J.Rmed.2015.09.003  0.523
2015 Han MK, Steenrod AW, Bacci ED, Leidy NK, Mannino DM, Thomashow BM, Barr RG, Make BJ, Bowler RP, Rennard SI, Houfek JF, Yawn BP, Meldrum CA, Walsh JW, Martinez FJ. Identifying Patients with Undiagnosed COPD in Primary Care Settings: Insight from Screening Tools and Epidemiologic Studies. Chronic Obstructive Pulmonary Diseases (Miami, Fla.). 2: 103-121. PMID 26236776 DOI: 10.15326/Jcopdf.2.2.2014.0152  0.377
2015 Strange C, Senior RM, Sciurba F, O'Neal S, Morris A, Wisniewski SR, Bowler R, Hochheiser HS, Becich MJ, Zhang Y, Leader JK, Methé BA, Kaminski N, Sandhaus RA. Rationale and Design of the Genomic Research in Alpha-1 Antitrypsin Deficiency and Sarcoidosis Study: Alpha-1 Protocol. Annals of the American Thoracic Society. PMID 26153726 DOI: 10.1513/Annalsats.201503-143Oc  0.336
2015 Yonchuk JG, Silverman EK, Bowler R, Agusti A, Lomas DA, Miller BE, Tal-Singer R, Mayer RJ. Circulating sRAGE as a Biomarker of Emphysema and the RAGE Axis in the Lung. American Journal of Respiratory and Critical Care Medicine. PMID 26132989 DOI: 10.1164/Rccm.201501-0137Pp  0.406
2015 Regan EA, Lynch DA, Curran-Everett D, Curtis JL, Austin JH, Grenier PA, Kauczor HU, Bailey WC, DeMeo DL, Casaburi RH, Friedman P, Van Beek EJ, Hokanson JE, Bowler RP, Beaty TH, et al. Clinical and Radiologic Disease in Smokers With Normal Spirometry. Jama Internal Medicine. PMID 26098755 DOI: 10.1001/Jamainternmed.2015.2735  0.583
2015 Leidy NK, Kim K, Bacci ED, Yawn BP, Mannino DM, Thomashow BM, Barr RG, Rennard SI, Houfek JF, Han MK, Meldrum CA, Make BJ, Bowler RP, Steenrod AW, Murray LT, et al. Identifying cases of undiagnosed, clinically significant COPD in primary care: qualitative insight from patients in the target population. Npj Primary Care Respiratory Medicine. 25: 15024. PMID 26028486 DOI: 10.1038/Npjpcrm.2015.24  0.41
2015 Jaramillo JD, Wilson C, Stinson DJ, Lynch DA, Bowler RP, Lutz S, Bon JM, Arnold B, McDonald ML, Washko GR, Wan ES, DeMeo DL, Foreman MG, Soler X, Lindsay SE, et al. Reduced Bone Density and Vertebral Fractures in Smokers. Men and COPD Patients at Increased Risk. Annals of the American Thoracic Society. 12: 648-56. PMID 25719895 DOI: 10.1513/Annalsats.201412-591Oc  0.53
2015 Nambu A, Zach J, Schroeder J, Jin GY, Kim SS, Kim YI, Schnell C, Bowler R, Lynch DA. Relationships between diffusing capacity for carbon monoxide (DLCO), and quantitative computed tomography measurements and visual assessment for chronic obstructive pulmonary disease. European Journal of Radiology. 84: 980-5. PMID 25704753 DOI: 10.1016/J.Ejrad.2015.01.010  0.33
2015 Pate KM, Sherk VD, Carpenter RD, Weaver M, Crapo S, Gally F, Chatham LS, Goldstrohm DA, Crapo JD, Kohrt WM, Bowler RP, Oberley-Deegan RE, Regan EA. The beneficial effects of exercise on cartilage are lost in mice with reduced levels of ECSOD in tissues. Journal of Applied Physiology (Bethesda, Md. : 1985). 118: 760-7. PMID 25593283 DOI: 10.1152/Japplphysiol.00112.2014  0.452
2015 Bowler RP, Jacobson S, Cruickshank C, Hughes GJ, Siska C, Ory DS, Petrache I, Schaffer JE, Reisdorph N, Kechris K. Plasma sphingolipids associated with chronic obstructive pulmonary disease phenotypes. American Journal of Respiratory and Critical Care Medicine. 191: 275-84. PMID 25494452 DOI: 10.1164/Rccm.201410-1771Oc  0.444
2015 Park SJ, Foreman MG, Demeo DL, Bhatt SP, Hansel NN, Wise RA, Soler X, Bowler RP. Menthol cigarette smoking in the COPDGene cohort: relationship with COPD, comorbidities and CT metrics. Respirology (Carlton, Vic.). 20: 108-14. PMID 25328036 DOI: 10.1111/Resp.12421  0.408
2015 Lee JH, Cho MH, Hersh CP, McDonald ML, Wells JM, Dransfield MT, Bowler RP, Lynch DA, Lomas DA, Crapo JD, Silverman EK. IREB2 and GALC are associated with pulmonary artery enlargement in chronic obstructive pulmonary disease. American Journal of Respiratory Cell and Molecular Biology. 52: 365-76. PMID 25101718 DOI: 10.1165/Rcmb.2014-0210Oc  0.583
2015 Koeverden Iv, Blanc PD, Bowler RP, Arjomandi M. Secondhand Tobacco Smoke and COPD Risk in Smokers: A COPDGene Study Cohort Subgroup Analysis. Copd. 12: 182-9. PMID 24983136 DOI: 10.3109/15412555.2014.922173  0.394
2015 Martinez F, Mannino DM, Leidy NK, Malley KG, Bacci ED, Barr RG, Bowler RP, Han MK, Houfek JF, Make BJ, Meldrum CA, Rennard S, Thomashow BM, Walsh JW, Yawn BP. LATE-BREAKING ABSTRACT: A novel approach for identifying patients with undiagnosed clinically-significant COPD European Respiratory Journal. 46. DOI: 10.1183/13993003.Congress-2015.Oa3284  0.382
2015 Pate KM, Sherk VD, Carpenter RD, Weaver M, Crapo S, Gally F, Chatham LS, Goldstrohm DA, Crapo JD, Kohrt WM, Bowler RP, Oberley-Deegan RE, Regan EA. The beneficial effects of exercise on cartilage are lost in mice with reduced levels of ECSOD in tissues Journal of Applied Physiology. 118: 760-767. DOI: 10.1152/japplphysiol.00112.2014  0.36
2014 Putcha N, Han MK, Martinez CH, Foreman MG, Anzueto AR, Casaburi R, Cho MH, Hanania NA, Hersh CP, Kinney GL, Make BJ, Steiner RM, Lutz SM, Thomashow BM, Williams AA, ... ... Bowler RP, et al. Comorbidities of COPD have a major impact on clinical outcomes, particularly in African Americans. Chronic Obstructive Pulmonary Diseases (Miami, Fla.). 1: 105-114. PMID 25695106 DOI: 10.15326/Jcopdf.1.1.2014.0112  0.517
2014 Wan ES, Qiu W, Carey VJ, Morrow J, Bacherman H, Foreman MG, Hokanson JE, Bowler RP, Crapo JD, DeMeo DL. Smoking Associated Site Specific Differential Methylation in Buccal Mucosa in the COPDGene Study. American Journal of Respiratory Cell and Molecular Biology. PMID 25517428 DOI: 10.1165/Rcmb.2014-0103Oc  0.519
2014 Hersh CP, Make BJ, Lynch DA, Barr RG, Bowler RP, Calverley PM, Castaldi PJ, Cho MH, Coxson HO, DeMeo DL, Foreman MG, Han MK, Harshfield BJ, Hokanson JE, Lutz S, et al. Non-emphysematous chronic obstructive pulmonary disease is associated with diabetes mellitus. Bmc Pulmonary Medicine. 14: 164. PMID 25341556 DOI: 10.1186/1471-2466-14-164  0.569
2014 Carolan BJ, Hughes G, Morrow J, Hersh CP, O'Neal WK, Rennard S, Pillai SG, Belloni P, Cockayne DA, Comellas AP, Han M, Zemans RL, Kechris K, Bowler RP. The association of plasma biomarkers with computed tomography-assessed emphysema phenotypes. Respiratory Research. 15: 127. PMID 25306249 DOI: 10.1186/S12931-014-0127-9  0.433
2014 Hobbs BD, Foreman MG, Bowler R, Jacobson F, Make BJ, Castaldi PJ, San José Estépar R, Silverman EK, Hersh CP. Pneumothorax risk factors in smokers with and without chronic obstructive pulmonary disease. Annals of the American Thoracic Society. 11: 1387-94. PMID 25295410 DOI: 10.1513/Annalsats.201405-224Oc  0.437
2014 Hartney JM, Stidham T, Goldstrohm DA, Oberley-Deegan RE, Weaver MR, Valnickova-Hansen Z, Scavenius C, Benninger RK, Leahy KF, Johnson R, Gally F, Kosmider B, Zimmermann AK, Enghild JJ, Nozik-Grayck E, ... Bowler RP, et al. A common polymorphism in extracellular superoxide dismutase affects cardiopulmonary disease risk by altering protein distribution. Circulation. Cardiovascular Genetics. 7: 659-66. PMID 25085920 DOI: 10.1161/Circgenetics.113.000504  0.362
2014 Cruickshank-Quinn CI, Mahaffey S, Justice MJ, Hughes G, Armstrong M, Bowler RP, Reisdorph R, Petrache I, Reisdorph N. Transient and persistent metabolomic changes in plasma following chronic cigarette smoke exposure in a mouse model. Plos One. 9: e101855. PMID 25007263 DOI: 10.1371/Journal.Pone.0101855  0.365
2014 Bowler RP, Kim V, Regan E, Williams AA, Santorico SA, Make BJ, Lynch DA, Hokanson JE, Washko GR, Bercz P, Soler X, Marchetti N, Criner GJ, Ramsdell J, Han MK, et al. Prediction of acute respiratory disease in current and former smokers with and without COPD. Chest. 146: 941-50. PMID 24945159 DOI: 10.1378/Chest.13-2946  0.553
2014 Castaldi PJ, Dy J, Ross J, Chang Y, Washko GR, Curran-Everett D, Williams A, Lynch DA, Make BJ, Crapo JD, Bowler RP, Regan EA, Hokanson JE, Kinney GL, Han MK, et al. Cluster analysis in the COPDGene study identifies subtypes of smokers with distinct patterns of airway disease and emphysema. Thorax. 69: 415-22. PMID 24563194 DOI: 10.1136/Thoraxjnl-2013-203601  0.529
2014 Janssen WJ, Yunt ZX, Muldrow A, Kearns MT, Kloepfer A, Barthel L, Bratton DL, Bowler RP, Henson PM. Circulating hematopoietic progenitor cells are decreased in COPD Copd: Journal of Chronic Obstructive Pulmonary Disease. 11: 277-289. PMID 24182349 DOI: 10.3109/15412555.2013.841668  0.351
2014 Merali S, Barrero CA, Bowler RP, Chen DE, Criner G, Braverman A, Litwin S, Yeung A, Kelsen SG. Analysis of the plasma proteome in COPD: Novel low abundance proteins reflect the severity of lung remodeling. Copd. 11: 177-89. PMID 24111704 DOI: 10.3109/15412555.2013.831063  0.396
2014 Hobbs BD, Foreman MG, Bowler R, Jacobson F, Make BJ, Castaldi PJ, Estépar RLSJ, Silverman EK, Hersh CP, Curtis J, Kazerooni E, Hanania N, Alapat P, Bandi V, Guntupalli K, et al. Pneumothorax risk factors in smokers with and without chronic obstructive pulmonary disease Annals of the American Thoracic Society. 11: 1387-1394. DOI: 10.1513/AnnalsATS.201405-224OC  0.306
2013 Han MK, Muellerova H, Curran-Everett D, Dransfield MT, Washko GR, Regan EA, Bowler RP, Beaty TH, Hokanson JE, Lynch DA, Jones PW, Anzueto A, Martinez FJ, Crapo JD, Silverman EK, et al. GOLD 2011 disease severity classification in COPDGene: a prospective cohort study. The Lancet. Respiratory Medicine. 1: 43-50. PMID 24321803 DOI: 10.1016/S2213-2600(12)70044-9  0.537
2013 Carolan BJ, Kim YI, Williams AA, Kechris K, Lutz S, Reisdorph N, Bowler RP. The association of adiponectin with computed tomography phenotypes in chronic obstructive pulmonary disease. American Journal of Respiratory and Critical Care Medicine. 188: 561-6. PMID 23777323 DOI: 10.1164/Rccm.201212-2299Oc  0.421
2013 Jiang D, Wenzel SE, Wu Q, Bowler RP, Schnell C, Chu HW. Human neutrophil elastase degrades SPLUNC1 and impairs airway epithelial defense against bacteria. Plos One. 8: e64689. PMID 23741370 DOI: 10.1371/Journal.Pone.0064689  0.393
2013 Estépar RS, Kinney GL, Black-Shinn JL, Bowler RP, Kindlmann GL, Ross JC, Kikinis R, Han MK, Come CE, Diaz AA, Cho MH, Hersh CP, Schroeder JD, Reilly JJ, Lynch DA, et al. Computed tomographic measures of pulmonary vascular morphology in smokers and their clinical implications. American Journal of Respiratory and Critical Care Medicine. 188: 231-9. PMID 23656466 DOI: 10.1164/Rccm.201301-0162Oc  0.551
2013 Kratzer A, Chu HW, Salys J, Moumen Z, Leberl M, Bowler R, Cool C, Zamora M, Taraseviciene-Stewart L. Endothelial cell adhesion molecule CD146: implications for its role in the pathogenesis of COPD. The Journal of Pathology. 230: 388-98. PMID 23649916 DOI: 10.1002/Path.4197  0.365
2013 Scavenius C, Petersen JS, Thomsen LR, Poulsen ET, Valnickova-Hansen Z, Bowler RP, Oury TD, Petersen SV, Enghild JJ. Murine extracellular superoxide dismutase is converted into the inactive fold by the Ser195Cys mutation Biochemistry. 52: 3369-3375. PMID 23594119 DOI: 10.1021/Bi400171B  0.556
2013 Bahr TM, Hughes GJ, Armstrong M, Reisdorph R, Coldren CD, Edwards MG, Schnell C, Kedl R, LaFlamme DJ, Reisdorph N, Kechris KJ, Bowler RP. Peripheral blood mononuclear cell gene expression in chronic obstructive pulmonary disease. American Journal of Respiratory Cell and Molecular Biology. 49: 316-23. PMID 23590301 DOI: 10.1165/Rcmb.2012-0230Oc  0.401
2013 Messier EM, Bahmed K, Tuder RM, Chu HW, Bowler RP, Kosmider B. Trolox contributes to Nrf2-mediated protection of human and murine primary alveolar type II cells from injury by cigarette smoke. Cell Death & Disease. 4: e573. PMID 23559007 DOI: 10.1038/Cddis.2013.96  0.391
2013 Holm KE, Borson S, Sandhaus RA, Ford DW, Strange C, Bowler RP, Make BJ, Wamboldt FS. Differences in adjustment between individuals with alpha-1 antitrypsin deficiency (AATD)-associated COPD and non-AATD COPD. Copd. 10: 226-34. PMID 23547634 DOI: 10.3109/15412555.2012.719049  0.359
2013 Messier EM, Day BJ, Bahmed K, Kleeberger SR, Tuder RM, Bowler RP, Chu HW, Mason RJ, Kosmider B. N-acetylcysteine protects murine alveolar type II cells from cigarette smoke injury in a nuclear erythroid 2-related factor-2-independent manner. American Journal of Respiratory Cell and Molecular Biology. 48: 559-67. PMID 23492188 DOI: 10.1165/Rcmb.2012-0295Oc  0.376
2013 Kratzer A, Salys J, Nold-Petry C, Cool C, Zamora M, Bowler R, Koczulla AR, Janciauskiene S, Edwards MG, Dinarello CA, Taraseviciene-Stewart L. Role of IL-18 in second-hand smoke-induced emphysema. American Journal of Respiratory Cell and Molecular Biology. 48: 725-32. PMID 23392573 DOI: 10.1165/Rcmb.2012-0173Oc  0.339
2013 Gally F, Chu HW, Bowler RP. Cigarette smoke decreases airway epithelial FABP5 expression and promotes Pseudomonas aeruginosa infection. Plos One. 8: e51784. PMID 23349676 DOI: 10.1371/Journal.Pone.0051784  0.394
2013 Wu Q, Case SR, Minor MN, Jiang D, Martin RJ, Bowler RP, Wang J, Hartney J, Karimpour-Fard A, Chu HW. A novel function of MUC18: amplification of lung inflammation during bacterial infection. The American Journal of Pathology. 182: 819-27. PMID 23256918 DOI: 10.1016/J.Ajpath.2012.11.005  0.413
2013 Villegas LR, Kluck D, Field C, Oberley-Deegan RE, Woods C, Yeager ME, El Kasmi KC, Savani RC, Bowler RP, Nozik-Grayck E. Superoxide dismutase mimetic, MnTE-2-PyP, attenuates chronic hypoxia-induced pulmonary hypertension, pulmonary vascular remodeling, and activation of the NALP3 inflammasome. Antioxidants & Redox Signaling. 18: 1753-64. PMID 23240585 DOI: 10.1089/Ars.2012.4799  0.348
2013 Packard TA, Li QZ, Cosgrove GP, Bowler RP, Cambier JC. COPD is associated with production of autoantibodies to a broad spectrum of self-antigens, correlative with disease phenotype Immunologic Research. 55: 48-57. PMID 22941590 DOI: 10.1007/S12026-012-8347-X  0.403
2012 Bowler RP. Surfactant protein D as a biomarker for chronic obstructive pulmonary disease. Copd. 9: 651-3. PMID 23244171 DOI: 10.3109/15412555.2012.736317  0.405
2012 Ginsburg SB, Lynch DA, Bowler RP, Schroeder JD. Automated texture-based quantification of centrilobular nodularity and centrilobular emphysema in chest CT images. Academic Radiology. 19: 1241-51. PMID 22958719 DOI: 10.1016/J.Acra.2012.04.020  0.305
2012 Wells JM, Washko GR, Han MK, Abbas N, Nath H, Mamary AJ, Regan E, Bailey WC, Martinez FJ, Westfall E, Beaty TH, Curran-Everett D, Curtis JL, Hokanson JE, Lynch DA, ... ... Bowler RP, et al. Pulmonary arterial enlargement and acute exacerbations of COPD. The New England Journal of Medicine. 367: 913-21. PMID 22938715 DOI: 10.1056/Nejmoa1203830  0.583
2012 Stewart JI, Moyle S, Criner GJ, Wilson C, Tanner R, Bowler RP, Crapo JD, Zeldin RK, Make BJ, Regan EA. Automated telecommunication to obtain longitudinal follow-up in a multicenter cross-sectional COPD study Copd: Journal of Chronic Obstructive Pulmonary Disease. 9: 466-472. PMID 22676387 DOI: 10.3109/15412555.2012.690010  0.502
2012 Barr RG, Berkowitz EA, Bigazzi F, Bode F, Bon J, Bowler RP, Chiles C, Crapo JD, Criner GJ, Curtis JL, Dass C, Dirksen A, Dransfield MT, Edula G, et al. A combined pulmonary-radiology workshop for visual evaluation of COPD: study design, chest CT findings and concordance with quantitative evaluation. Copd. 9: 151-9. PMID 22429093 DOI: 10.3109/15412555.2012.654923  0.524
2012 Pate K, Oberley-Deegan R, Weaver M, Gally F, Goldstrohm D, Crapo J, Bowler R, Regan E. Forced Running Elicits Arthritis and Oxidative Damage in Antioxidant Impaired Mice Free Radical Biology and Medicine. 53: S128. DOI: 10.1016/J.Freeradbiomed.2012.10.319  0.451
2011 Han MK, Kazerooni EA, Lynch DA, Liu LX, Murray S, Curtis JL, Criner GJ, Kim V, Bowler RP, Hanania NA, Anzueto AR, Make BJ, Hokanson JE, Crapo JD, Silverman EK, et al. Chronic obstructive pulmonary disease exacerbations in the COPDGene study: Associated radiologic phenotypes Radiology. 261: 274-282. PMID 21788524 DOI: 10.1148/Radiol.11110173  0.573
2011 Kim YI, Schroeder J, Lynch D, Newell J, Make B, Friedlander A, Estépar RS, Hanania NA, Washko G, Murphy JR, Wilson C, Hokanson JE, Zach J, Butterfield K, Bowler RP, et al. Gender differences of airway dimensions in anatomically matched sites on CT in smokers. Copd. 8: 285-92. PMID 21756032 DOI: 10.3109/15412555.2011.586658  0.318
2011 Nicks ME, O'Brien MM, Bowler RP. Plasma antioxidants are associated with impaired lung function and COPD exacerbations in smokers. Copd. 8: 264-9. PMID 21627570 DOI: 10.3109/15412555.2011.579202  0.813
2011 Regan EA, Mazur W, Meoni E, Toljamo T, Millar J, Vuopala K, Bowler RP, Rahman I, Nicks ME, Crapo JD, Kinnula VL. Smoking and COPD increase sputum levels of extracellular superoxide dismutase Free Radical Biology and Medicine. 51: 726-732. PMID 21621610 DOI: 10.1016/J.Freeradbiomed.2011.05.008  0.808
2011 Polosukhin VV, Cates JM, Lawson WE, Zaynagetdinov R, Milstone AP, Massion PP, Ocak S, Ware LB, Lee JW, Bowler RP, Kononov AV, Randell SH, Blackwell TS. Bronchial secretory immunoglobulin a deficiency correlates with airway inflammation and progression of chronic obstructive pulmonary disease. American Journal of Respiratory and Critical Care Medicine. 184: 317-27. PMID 21512171 DOI: 10.1164/Rccm.201010-1629Oc  0.457
2011 Hoth KF, Wamboldt FS, Bowler R, Make B, Holm KE. Attributions about cause of illness in chronic obstructive pulmonary disease. Journal of Psychosomatic Research. 70: 465-72. PMID 21511077 DOI: 10.1016/J.Jpsychores.2010.10.005  0.383
2011 Tooker BC, Bowler RP, Orcutt JM, Maier LA, Christensen HM, Newman LS. SELDI-TOF derived serum biomarkers failed to differentiate between patients with beryllium sensitisation and patients with chronic beryllium disease. Occupational and Environmental Medicine. 68: 759-64. PMID 21278142 DOI: 10.1136/Oem.2010.058966  0.313
2011 Simon GC, Martin RJ, Smith S, Thaikoottathil J, Bowler RP, Barenkamp SJ, Chu HW. Up-regulation of MUC18 in airway epithelial cells by IL-13: implications in bacterial adherence. American Journal of Respiratory Cell and Molecular Biology. 44: 606-13. PMID 21239604 DOI: 10.1165/Rcmb.2010-0384Oc  0.338
2011 Zhang W, Case S, Bowler RP, Martin RJ, Jiang D, Chu HW. Cigarette smoke modulates PGE(2) and host defence against Moraxella catarrhalis infection in human airway epithelial cells. Respirology (Carlton, Vic.). 16: 508-16. PMID 21199162 DOI: 10.1111/J.1440-1843.2010.01920.X  0.356
2011 Villegas LR, Field C, Kluck D, Yeager M, El Kasmi K, Oberley-Deegan R, Bowler R, Savani R, Nozik-Grayck E. Superoxide Dismutase Mimetic Attenuates Hypoxia-Induced Pulmonary Vascular Remodeling, ECM Hyaluronan Expression, and NALP3-Mediated Inflammation Free Radical Biology and Medicine. 51: S116. DOI: 10.1016/J.Freeradbiomed.2011.10.364  0.353
2011 Goldstrohm DA, Oberley-Deegan RE, Weaver MR, Valnickova Z, Enghild JJ, Mason RJ, Oury TD, Tollefson AK, Petersen SV, Bowler RP. Mechanisms by Which the EC-SOD R213G SNP Reduces the Risk for Lung Disease Free Radical Biology and Medicine. 51: S111. DOI: 10.1016/J.Freeradbiomed.2011.10.349  0.612
2010 Moré JM, Voelker DR, Silveira LJ, Edwards MG, Chan ED, Bowler RP. Smoking reduces surfactant protein D and phospholipids in patients with and without chronic obstructive pulmonary disease. Bmc Pulmonary Medicine. 10: 53. PMID 20973980 DOI: 10.1186/1471-2466-10-53  0.422
2010 Tollefson AK, Oberley-Deegan RE, Butterfield KT, Nicks ME, Weaver MR, Remigio LK, Decsesznak J, Chu HW, Bratton DL, Riches DW, Bowler RP. Endogenous enzymes (NOX and ECSOD) regulate smoke-induced oxidative stress. Free Radical Biology & Medicine. 49: 1937-46. PMID 20887783 DOI: 10.1016/J.Freeradbiomed.2010.09.022  0.79
2010 Holm KE, LaChance HR, Bowler RP, Make BJ, Wamboldt FS. Family factors are associated with psychological distress and smoking status in chronic obstructive pulmonary disease. General Hospital Psychiatry. 32: 492-8. PMID 20851269 DOI: 10.1016/J.Genhosppsych.2010.06.007  0.401
2010 Gross CA, Bowler RP, Green RM, Weinberger AR, Schnell C, Chu HW. beta2-agonists promote host defense against bacterial infection in primary human bronchial epithelial cells. Bmc Pulmonary Medicine. 10: 30. PMID 20470412 DOI: 10.1186/1471-2466-10-30  0.322
2009 Bowler RP, Reisdorph N, Reisdorph R, Abraham E. Alterations in the human lung proteome with lipopolysaccharide. Bmc Pulmonary Medicine. 9: 20. PMID 19432985 DOI: 10.1186/1471-2466-9-20  0.312
2009 Richens TR, Linderman DJ, Horstmann SA, Lambert C, Xiao YQ, Keith RL, Boé DM, Morimoto K, Bowler RP, Day BJ, Janssen WJ, Henson PM, Vandivier RW. Cigarette smoke impairs clearance of apoptotic cells through oxidant-dependent activation of RhoA. American Journal of Respiratory and Critical Care Medicine. 179: 1011-21. PMID 19264974 DOI: 10.1164/Rccm.200807-1148Oc  0.453
2009 Arcaroli JJ, Hokanson JE, Abraham E, Geraci M, Murphy JR, Bowler RP, Dinarello CA, Silveira L, Sankoff J, Heyland D, Wischmeyer P, Crapo JD. Extracellular superoxide dismutase haplotypes are associated with acute lung injury and mortality American Journal of Respiratory and Critical Care Medicine. 179: 105-112. PMID 18948423 DOI: 10.1164/Rccm.200710-1566Oc  0.563
2008 Dahl M, Bowler RP, Juul K, Crapo JD, Levy S, Nordestgaard BG. Superoxide dismutase 3 polymorphism associated with reduced lung function in two large populations American Journal of Respiratory and Critical Care Medicine. 178: 906-912. PMID 18703790 DOI: 10.1164/Rccm.200804-549Oc  0.549
2008 Baqir M, Chen CZ, Martin RJ, Thaikoottathil J, Case SR, Minor MN, Bowler R, Chu HW. Cigarette smoke decreases MARCO expression in macrophages: implication in Mycoplasma pneumoniae infection. Respiratory Medicine. 102: 1604-10. PMID 18590957 DOI: 10.1016/J.Rmed.2008.05.002  0.358
2008 Regan EA, Bowler RP, Crapo JD. Joint fluid antioxidants are decreased in osteoarthritic joints compared to joints with macroscopically intact cartilage and subacute injury Osteoarthritis and Cartilage. 16: 515-521. PMID 18203633 DOI: 10.1016/J.Joca.2007.09.001  0.448
2008 Gingo MR, Silveira LJ, Miller YE, Friedlander AL, Cosgrove GP, Chan ED, Maier LA, Bowler RP. Tumour necrosis factor gene polymorphisms are associated with COPD European Respiratory Journal. 31: 1005-1012. DOI: 10.1183/09031936.00100307  0.392
2007 Friedlander AL, Lynch D, Dyar LA, Bowler RP. Phenotypes of chronic obstructive pulmonary disease. Copd. 4: 355-84. PMID 18027163 DOI: 10.1080/15412550701629663  0.47
2007 Chu HW, Thaikoottathil J, Rino JG, Zhang G, Wu Q, Moss T, Refaeli Y, Bowler R, Wenzel SE, Chen Z, Zdunek J, Breed R, Young R, Allaire E, Martin RJ. Function and regulation of SPLUNC1 protein in Mycoplasma infection and allergic inflammation. Journal of Immunology (Baltimore, Md. : 1950). 179: 3995-4002. PMID 17785838 DOI: 10.4049/Jimmunol.179.6.3995  0.3
2006 Sutherland ER, Crapo JD, Bowler RP. N-acetylcysteine and exacerbations of chronic obstructive pulmonary disease Copd: Journal of Chronic Obstructive Pulmonary Disease. 3: 195-202. PMID 17361500 DOI: 10.1080/15412550600977361  0.538
2006 Bowler RP, Canham ME, Ellison MC. Surface enhanced laser desorption/ionization (SELDI) time-of-flight mass spectrometry to identify patients with chronic obstructive pulmonary disease. Copd. 3: 41-50. PMID 17175664 DOI: 10.1080/15412550500493394  0.388
2006 Bowler RP, Ellison MC, Reisdorph N. Proteomics in pulmonary medicine. Chest. 130: 567-74. PMID 16899860 DOI: 10.1378/Chest.130.2.567  0.367
2006 Sharma S, Dewald O, Adrogue J, Salazar RL, Razeghi P, Crapo JD, Bowler RP, Entman ML, Taegtmeyer H. Induction of antioxidant gene expression in a mouse model of ischemic cardiomyopathy is dependent on reactive oxygen species Free Radical Biology and Medicine. 40: 2223-2231. PMID 16785036 DOI: 10.1016/J.Freeradbiomed.2006.02.019  0.452
2006 Morimoto K, Janssen WJ, Fessler MB, McPhillips KA, Borges VM, Bowler RP, Xiao YQ, Kench JA, Henson PM, Vandivier RW. Lovastatin enhances clearance of apoptotic cells (efferocytosis) with implications for chronic obstructive pulmonary disease. Journal of Immunology (Baltimore, Md. : 1950). 176: 7657-65. PMID 16751413 DOI: 10.4049/Jimmunol.176.12.7657  0.419
2006 Regan EA, Bowler RP, Crapo JD. 58 PLASMA EXTRACELLULAR SUPEROXIDE DISMUTASE IS DECREASED IN HIGH-ALTITUDE MOUNTAINEERS WHO ARE ENDURANCE TRAINED. Journal of Investigative Medicine. 54: S383.3-S383. DOI: 10.2310/6650.2005.X0015.136  0.497
2006 Bowler RP, Hokanson J, Taylor M, Levy S, Canaham EM, Regan E, Wheeler C, Nicks M, Chan E, Crapo JD. Extracellular superoxide dismutase (EC-SOD) as a protective factor for risk of chronic obstructive pulmonary disease European Respiratory Review. 15: 200-201. DOI: 10.1183/09059180.00010117  0.509
2005 Regan E, Flannelly J, Bowler R, Tran K, Nicks M, Carbone BD, Glueck D, Heijnen H, Mason R, Crapo J. Extracellular superoxide dismutase and oxidant damage in osteoarthritis. Arthritis and Rheumatism. 52: 3479-91. PMID 16255039 DOI: 10.1002/Art.21387  0.747
2004 Bowler RP, Barnes PJ, Crapo JD. The role of oxidative stress in chronic obstructive pulmonary disease Copd. 1: 255-277. PMID 17136992 DOI: 10.1081/Copd-200027031  0.602
2004 Bowler RP, Ellison MC, Duda B, Tran K, Nicks M, Cool C, Greene K, Crapo JD. Lung inflation with direct injection of agarose: a technique for simultaneous molecular and morphometric measurements. Experimental Lung Research. 30: 673-86. PMID 15700546 DOI: 10.1080/01902140490517845  0.51
2004 Heijnen HF, Waaijenborg S, Crapo JD, Bowler RP, Akkerman JW, Slot JW. Colocalization of eNOS and the catalytic subunit of PKA in endothelial cell junctions: a clue for regulated NO production. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 52: 1277-85. PMID 15385574 DOI: 10.1177/002215540405201004  0.439
2004 Bowler RP, Nicks M, Tran K, Tanner G, Chang LY, Young SK, Worthen GS. Extracellular superoxide dismutase attenuates lipopolysaccharide-induced neutrophilic inflammation. American Journal of Respiratory Cell and Molecular Biology. 31: 432-9. PMID 15256385 DOI: 10.1165/Rcmb.2004-0057Oc  0.348
2004 Sutherland ER, Martin RJ, Bowler RP, Zhang Y, Rex MD, Kraft M. Physiologic correlates of distal lung inflammation in asthma. The Journal of Allergy and Clinical Immunology. 113: 1046-50. PMID 15208583 DOI: 10.1016/J.Jaci.2004.03.016  0.341
2004 Bowler RP, Duda B, Vu KO, Byers T, Franklin W, Chan ED, Miller YE. Airway antioxidants and oxidative stress as predictors of sputum atypia and airflow obstruction. Chest. 125: 127S-8S. PMID 15136460 DOI: 10.1378/Chest.125.5_Suppl.127S  0.323
2004 Bowler RP. Oxidative stress in the pathogenesis of asthma. Current Allergy and Asthma Reports. 4: 116-22. PMID 14769260 DOI: 10.1007/S11882-004-0056-7  0.311
2004 Bowler RP, Duda B, Chan ED, Enghild JJ, Ware LB, Matthay MA, Duncan MW. Proteomic analysis of pulmonary edema fluid and plasma in patients with acute lung injury. American Journal of Physiology. Lung Cellular and Molecular Physiology. 286: L1095-104. PMID 14742308 DOI: 10.1152/Ajplung.00304.2003  0.336
2004 Petersen SV, Oury TD, Ostergaard L, Valnickova Z, Wegrzyn J, Thøgersen IB, Jacobsen C, Bowler RP, Fattman CL, Crapo JD, Enghild JJ. Extracellular Superoxide Dismutase (EC-SOD) Binds to Type I Collagen and Protects Against Oxidative Fragmentation Journal of Biological Chemistry. 279: 13705-13710. PMID 14736885 DOI: 10.1074/Jbc.M310217200  0.637
2003 Bowler RP, Velsor LW, Duda B, Chan ED, Abraham E, Ware LB, Matthay MA, Day BJ. Pulmonary edema fluid antioxidants are depressed in acute lung injury. Critical Care Medicine. 31: 2309-15. PMID 14501961 DOI: 10.1097/01.Ccm.0000085090.06078.8C  0.349
2003 Bowler RP, Arcaroli J, Abraham E, Patel M, Chang LY, Crapo JD. Evidence for extracellular superoxide dismutase as a mediator of hemorrhage-induced lung injury. American Journal of Physiology. Lung Cellular and Molecular Physiology. 284: L680-7. PMID 12618426 DOI: 10.1152/Ajplung.00191.2002  0.527
2003 Wang W, Jittikanont S, Falk SA, Li P, Feng L, Gengaro PE, Poole BD, Bowler RP, Day BJ, Crapo JD, Schrier RW. Interaction among nitric oxide, reactive oxygen species, and antioxidants during endotoxemia-related acute renal failure. American Journal of Physiology. Renal Physiology. 284: F532-7. PMID 12556364 DOI: 10.1152/Ajprenal.00323.2002  0.448
2002 Bowler RP, Crapo JD. Oxidative stress in airways: Is there a role for extracellular superoxide dismutase? American Journal of Respiratory and Critical Care Medicine. 166: S38-S43. PMID 12471087 DOI: 10.1164/Rccm.2206014  0.561
2002 Bowler RP, Sheng H, Enghild JJ, Pearlstein RD, Warner DS, Crapo JD. A catalytic antioxidant (AEOL 10150) attenuates expression of inflammatory genes in stroke Free Radical Biology and Medicine. 33: 1141-1152. PMID 12374626 DOI: 10.1016/S0891-5849(02)01008-0  0.449
2002 Sheng H, Enghild JJ, Bowler R, Patel M, Batinić-Haberle I, Calvi CL, Day BJ, Pearlstein RD, Crapo JD, Warner DS. Effects of metalloporphyrin catalytic antioxidants in experimental brain ischemia. Free Radical Biology & Medicine. 33: 947-61. PMID 12361805 DOI: 10.1016/S0891-5849(02)00979-6  0.421
2002 Bowler RP, Crapo JD. Oxidative stress in allergic respiratory diseases Journal of Allergy and Clinical Immunology. 110: 349-356. PMID 12209079 DOI: 10.1067/Mai.2002.126780  0.513
2002 Bowler RP, Nicks M, Warnick K, Crapo JD. Role of extracellular superoxide dismutase in bleomycin-induced pulmonary fibrosis American Journal of Physiology - Lung Cellular and Molecular Physiology. 282: L719-L726. PMID 11880297 DOI: 10.1152/Ajplung.00058.2001  0.554
2002 Bowler RP, Nicks M, Olsen DA, Thøgersen IB, Valnickova Z, Højrup P, Franzusoff A, Enghild JJ, Crapo JD. Furin proteolytically processes the heparin-binding region of extracellular superoxide dismutase Journal of Biological Chemistry. 277: 16505-16511. PMID 11861638 DOI: 10.1074/Jbc.M105409200  0.754
2002 Bowler RP, Patel M, Chang L, Crapo J. EVIDENCE FOR EXTRACELLULAR SUPEROXIDE AS A MEDIATOR OF HEMORRHAGE-INDUCED LUNG INJURY Critical Care Medicine. 30: A41. DOI: 10.1097/00003246-200212001-00143  0.5
2001 Bowler RP, Arcaroli J, Crapo JD, Ross A, Slot JW, Abraham E. Extracellular superoxide dismutase attenuates lung injury after hemorrhage American Journal of Respiratory and Critical Care Medicine. 164: 290-294. PMID 11463603 DOI: 10.1164/Ajrccm.164.2.2011054  0.531
2001 Pineda JA, Aono M, Sheng H, Lynch J, Wellons JC, Laskowitz DT, Pearlstein RD, Bowler R, Crapo J, Warner DS. Extracellular superoxide dismutase overexpression improves behavioral outcome from closed head injury in the mouse. Journal of Neurotrauma. 18: 625-34. PMID 11437085 DOI: 10.1089/089771501750291864  0.457
2001 Bowler RP, Nicks M, Crapo J. Mice Overexpressing Extracellular Superoxide Dismutase Are Resistant to Bleomycin-Induced Pulmonary Injury Chest. 120: S10. DOI: 10.1016/S0012-3692(15)38676-1  0.493
1998 Schwarz MI, Zamora MR, Hodges TN, Chan ED, Bowler RP, Tuder RM. Isolated pulmonary capillaritis and diffuse alveolar hemorrhage in rheumatoid arthritis and mixed connective tissue disease. Chest. 113: 1609-15. PMID 9631801 DOI: 10.1378/Chest.113.6.1609  0.325
1998 Bowler RP, Durham J, Schwarz MI. Massive hemoptysis from a pulmonary artery aneurysm associated with an emphysematous bulla. Chest. 113: 1130-1. PMID 9554660 DOI: 10.1378/Chest.113.4.1130  0.317
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