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Mala Mani, Ph.D. - Publications

Affiliations: 
2006 Johns Hopkins University, Baltimore, MD 
Area:
Molecular Biology
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20 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2013 Gatt ME, Takada K, Mani M, Lerner M, Pick M, Hideshima T, Carrasco DE, Protopopov A, Ivanova E, Sangfelt O, Grandér D, Barlogie B, Shaughnessy JD, Anderson KC, Carrasco DR. TRIM13 (RFP2) downregulation decreases tumour cell growth in multiple myeloma through inhibition of NF Kappa B pathway and proteasome activity. British Journal of Haematology. 162: 210-20. PMID 23647456 DOI: 10.1111/Bjh.12365  0.372
2012 Takada K, Zhu D, Bird GH, Sukhdeo K, Zhao JJ, Mani M, Lemieux M, Carrasco DE, Ryan J, Horst D, Fulciniti M, Munshi NC, Xu W, Kung AL, Shivdasani RA, et al. Targeted disruption of the BCL9/β-catenin complex inhibits oncogenic Wnt signaling. Science Translational Medicine. 4: 148ra117. PMID 22914623 DOI: 10.1126/Scitranslmed.3003808  0.32
2010 Gatt ME, Zhao JJ, Ebert MS, Zhang Y, Chu Z, Mani M, Gazit R, Carrasco DE, Dutta-Simmons J, Adamia S, Minvielle S, Tai YT, Munshi NC, Avet-Loiseau H, Anderson KC, et al. MicroRNAs 15a/16-1 function as tumor suppressor genes in multiple myeloma. Blood. PMID 20962322 DOI: 10.1182/Blood-2009-11-253294  0.422
2010 Görgün G, Calabrese E, Hideshima T, Ecsedy J, Perrone G, Mani M, Ikeda H, Bianchi G, Hu Y, Cirstea D, Santo L, Tai YT, Nahar S, Zheng M, Bandi M, et al. A novel Aurora-A kinase inhibitor MLN8237 induces cytotoxicity and cell-cycle arrest in multiple myeloma. Blood. 115: 5202-13. PMID 20382844 DOI: 10.1182/Blood-2009-12-259523  0.369
2010 Zhao J, Lin J, Chu Z, Wang Q, Takada K, Mani M, Ciccarelli B, Hideshima T, Yu-Tzu T, Tao J, Treon SP, Munshi NC, Anderson KC, Carrasco R. Bone Marrow Niche Down-Regulates Mir-30 In Multiple Myeloma Cells to Promote Cancer Progression and Cancer Initiation by Targeting BCL9/Wnt Pathway. Blood. 116: 1569-1569. DOI: 10.1182/Blood.V116.21.1569.1569  0.307
2009 Mani M, Carrasco DE, Zhang Y, Takada K, Gatt ME, Dutta-Simmons J, Ikeda H, Diaz-Griffero F, Pena-Cruz V, Bertagnolli M, Myeroff LL, Markowitz SD, Anderson KC, Carrasco DR. BCL9 promotes tumor progression by conferring enhanced proliferative, metastatic, and angiogenic properties to cancer cells. Cancer Research. 69: 7577-86. PMID 19738061 DOI: 10.1158/0008-5472.Can-09-0773  0.342
2009 Dutta-Simmons J, Zhang Y, Gorgun G, Gatt M, Mani M, Hideshima T, Takada K, Carlson NE, Carrasco DE, Tai YT, Raje N, Letai AG, Anderson KC, Carrasco DR. Aurora kinase A is a target of Wnt/beta-catenin involved in multiple myeloma disease progression. Blood. 114: 2699-708. PMID 19652203 DOI: 10.1182/Blood-2008-12-194290  0.337
2009 Kandavelou K, Ramalingam S, London V, Mani M, Wu J, Alexeev V, Civin CI, Chandrasegaran S. Targeted manipulation of mammalian genomes using designed zinc finger nucleases. Biochemical and Biophysical Research Communications. 388: 56-61. PMID 19635463 DOI: 10.1016/J.Bbrc.2009.07.112  0.657
2009 Gatt ME, Ebert M, Mani M, Zhang Y, Gazit R, Carrasco DE, Dutta J, Adamia S, Munshi NC, Minvielle S, Avet-Loiseau H, Tai Y, Anderson KC, Carrasco DR. The Functional Role of Microrna 15a/16-1 as Tumor Suppressor Genes in Multiple Myeloma. Blood. 114: 1963-1963. DOI: 10.1182/Blood.V114.22.1963.1963  0.372
2009 Gatt ME, Mani M, Lerner M, Hideshima T, Zhang Y, Dutta J, Carrasco DE, Protopopov A, Sangfelt O, Grander D, Barlogie B, Shaughnessy JD, Anderson KC, Carrasco DR. RFP2 Modulates 20S Proteasome Activity, NF Kappa B Activation, and Tumor Cell Growth in Multiple Myeloma. Blood. 114: 1786-1786. DOI: 10.1182/Blood.V114.22.1786.1786  0.4
2008 Mani M, Dutta J, Zhang Y, Carrasco DE, Zhou Y, Gatt M, Barlogie B, Shaughnessy JD, Anderson KC, Carrasco DR. The BCL9 Oncogene Promotes Tumor Progression by Conferring Enhanced Proliferative, Metastatic and Angiogenic Properties to Myeloma Cells Blood. 112: 648-648. DOI: 10.1182/Blood.V112.11.648.648  0.403
2008 Gatt ME, Mani M, Dutta J, Carrasco DE, Shaughnessy JD, Anderson KC, Carrasco DR. RFP2 Knockdown Disrupts Cell Growth and Induces Apoptosis in Multiple Myeloma Blood. 112: 5327-5327. DOI: 10.1182/Blood.V112.11.5327.5327  0.406
2008 Gorgun G, Calabrese E, Mani M, Hideshima T, Ikeda H, Perrone G, Santo L, Cirstea D, Blotta S, Richardson PG, Ecsedy J, Anderson KC. A Novel Aurora-a Kinase Inhibitor MLN8237 Induces Cytotoxicity and Cell Cycle Arrest in Experimental Multiple Myeloma Models. Blood. 112: 1719-1719. DOI: 10.1182/Blood.V112.11.1719.1719  0.341
2007 Sukhdeo K, Mani M, Zhang Y, Dutta J, Yasui H, Rooney MD, Carrasco DE, Zheng M, He H, Tai YT, Mitsiades C, Anderson KC, Carrasco DR. Targeting the beta-catenin/TCF transcriptional complex in the treatment of multiple myeloma. Proceedings of the National Academy of Sciences of the United States of America. 104: 7516-21. PMID 17452641 DOI: 10.1073/Pnas.0610299104  0.384
2007 Carrasco DR, Sukhdeo K, Protopopova M, Sinha R, Enos M, Carrasco DE, Zheng M, Mani M, Henderson J, Pinkus GS, Munshi N, Horner J, Ivanova EV, Protopopov A, Anderson KC, et al. The differentiation and stress response factor XBP-1 drives multiple myeloma pathogenesis. Cancer Cell. 11: 349-60. PMID 17418411 DOI: 10.1016/J.Ccr.2007.02.015  0.325
2007 Raje N, Hideshima T, Vallet S, Cirstea D, Kiziltepe T, Chhetri S, Mani M, Mukherjee S, Carrasco DR, Mitsiades C, Rooney M, Podar K, Okawa Y, Ikeda H, Richardson PG, et al. Preclinical Validation of a Clinical Grade Novel Specific Small Molecule Cyclin D1 Inhibitor, P276-00 for the Treatment of Multiple Myeloma. Blood. 110: 256-256. DOI: 10.1182/Blood.V110.11.256.256  0.332
2005 Durai S, Mani M, Kandavelou K, Wu J, Porteus MH, Chandrasegaran S. Zinc finger nucleases: custom-designed molecular scissors for genome engineering of plant and mammalian cells. Nucleic Acids Research. 33: 5978-90. PMID 16251401 DOI: 10.1093/Nar/Gki912  0.664
2005 Mani M, Kandavelou K, Dy FJ, Durai S, Chandrasegaran S. Design, engineering, and characterization of zinc finger nucleases. Biochemical and Biophysical Research Communications. 335: 447-57. PMID 16084494 DOI: 10.1016/J.Bbrc.2005.07.089  0.668
2005 Mani M, Smith J, Kandavelou K, Berg JM, Chandrasegaran S. Binding of two zinc finger nuclease monomers to two specific sites is required for effective double-strand DNA cleavage. Biochemical and Biophysical Research Communications. 334: 1191-7. PMID 16043120 DOI: 10.1016/J.Bbrc.2005.07.021  0.594
2005 Kandavelou K, Mani M, Durai S, Chandrasegaran S. "Magic" scissors for genome surgery. Nature Biotechnology. 23: 686-7. PMID 15940239 DOI: 10.1038/Nbt0605-686  0.602
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