Jakob Fuhrmann - Publications

Affiliations: 
2016 Chemistry The Scripps Research Institute, Scripps Florida 

18 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Wu H, Murray J, Ishisoko N, Frommlet A, Deshmukh G, DiPasquale A, Mulvihill MM, Zhang D, Quinn JG, Blake RA, Fairbrother WJ, Fuhrmann J. Potency-Enhanced Peptidomimetic VHL Ligands with Improved Oral Bioavailability. Journal of Medicinal Chemistry. PMID 38809766 DOI: 10.1021/acs.jmedchem.3c02203  0.303
2020 Bashore C, Jaishankar P, Skelton NJ, Fuhrmann J, Hearn BR, Liu PS, Renslo AR, Dueber EC. Cyanopyrrolidine Inhibitors of Ubiquitin Specific Protease 7 Mediate Desulfhydration of the Active-Site Cysteine. Acs Chemical Biology. PMID 32302100 DOI: 10.1021/Acschembio.0C00031  0.444
2017 Brust R, Lin H, Fuhrmann J, Asteian A, Kamenecka TM, Kojetin DJ. Modification of the Orthosteric PPARγ Covalent Antagonist Scaffold Yields an Improved Dual-Site Allosteric Inhibitor. Acs Chemical Biology. PMID 28165718 DOI: 10.1021/Acschembio.6B01015  0.319
2016 Hughes TS, Shang J, Brust R, de Vera IM, Fuhrmann J, Ruiz C, Cameron MD, Kamenecka TM, Kojetin DJ. Probing the Complex Binding Modes of the PPARγ Partial Agonist 2-chloro-N-(3-chloro-4-((5-chlorobenzo[d]thiazol-2-yl)thio)phenyl)-4-(trifluoromethyl)benzenesulfonamide (T2384) to Orthosteric and Allosteric Sites with NMR Spectroscopy. Journal of Medicinal Chemistry. PMID 27783520 DOI: 10.1021/Acs.Jmedchem.6B01340  0.318
2016 Fuhrmann J, Subramanian V, Kojetin DJ, Thompson PR. Activity-Based Profiling Reveals a Regulatory Link between Oxidative Stress and Protein Arginine Phosphorylation. Cell Chemical Biology. PMID 27524296 DOI: 10.1016/J.Chembiol.2016.07.008  0.706
2015 Fuhrmann J, Thompson PR. Protein Arginine Methylation and Citrullination in Epigenetic Regulation. Acs Chemical Biology. PMID 26686581 DOI: 10.1021/Acschembio.5B00942  0.56
2015 Fuhrmann J, Subramanian V, Thompson PR. Synthesis and Use of a Phosphonate Amidine to Generate an Anti-Phosphoarginine-Specific Antibody. Angewandte Chemie (International Ed. in English). PMID 26458230 DOI: 10.1002/Anie.201506737  0.577
2015 Fuhrmann J, Clancy KW, Thompson PR. Chemical Biology of Protein Arginine Modifications in Epigenetic Regulation. Chemical Reviews. 115: 5413-61. PMID 25970731 DOI: 10.1021/Acs.Chemrev.5B00003  0.551
2015 Slade DJ, Fang P, Dreyton CJ, Zhang Y, Fuhrmann J, Rempel D, Bax BD, Coonrod SA, Lewis HD, Guo M, Gross ML, Thompson PR. Protein arginine deiminase 2 binds calcium in an ordered fashion: implications for inhibitor design. Acs Chemical Biology. 10: 1043-53. PMID 25621824 DOI: 10.1021/Cb500933J  0.694
2014 Schmidt A, Trentini DB, Spiess S, Fuhrmann J, Ammerer G, Mechtler K, Clausen T. Quantitative Phosphoproteomics Reveals the Role of Protein Arginine Phosphorylation in the Bacterial Stress Response. Molecular & Cellular Proteomics : McP. 13: 537-550. PMID 33498137 DOI: 10.1074/mcp.M113.032292  0.775
2014 Wang M, Fuhrmann J, Thompson PR. Protein arginine methyltransferase 5 catalyzes substrate dimethylation in a distributive fashion. Biochemistry. 53: 7884-92. PMID 25485739 DOI: 10.1021/Bi501279G  0.591
2014 Trentini DB, Fuhrmann J, Mechtler K, Clausen T. Chasing Phosphoarginine Proteins: Development of a Selective Enrichment Method Using a Phosphatase Trap. Molecular & Cellular Proteomics : McP. 13: 1953-64. PMID 24825175 DOI: 10.1074/Mcp.O113.035790  0.736
2014 Schmidt A, Trentini DB, Spiess S, Fuhrmann J, Ammerer G, Mechtler K, Clausen T. Quantitative phosphoproteomics reveals the role of protein arginine phosphorylation in the bacterial stress response. Molecular & Cellular Proteomics : McP. 13: 537-50. PMID 24263382 DOI: 10.1074/Mcp.M113.032292  0.715
2014 Slade DJ, Subramanian V, Fuhrmann J, Thompson PR. Chemical and biological methods to detect post-translational modifications of arginine. Biopolymers. 101: 133-43. PMID 23576281 DOI: 10.1002/Bip.22256  0.736
2013 Fuhrmann J, Subramanian V, Thompson PR. Targeting the arginine phosphatase YwlE with a catalytic redox-based inhibitor. Acs Chemical Biology. 8: 2024-32. PMID 23838530 DOI: 10.1021/Cb4001469  0.597
2013 Fuhrmann J, Mierzwa B, Trentini DB, Spiess S, Lehner A, Charpentier E, Clausen T. Structural basis for recognizing phosphoarginine and evolving residue-specific protein phosphatases in gram-positive bacteria. Cell Reports. 3: 1832-9. PMID 23770242 DOI: 10.1016/J.Celrep.2013.05.023  0.73
2009 Fuhrmann J, Schmidt A, Spiess S, Lehner A, Turgay K, Mechtler K, Charpentier E, Clausen T. McsB is a protein arginine kinase that phosphorylates and inhibits the heat-shock regulator CtsR. Science (New York, N.Y.). 324: 1323-7. PMID 19498169 DOI: 10.1126/Science.1170088  0.77
2007 Krojer T, Sawa J, Fuhrmann J, Gazda L, Kirk R, Kurt J, Nussbaumer B, Schmidt B, Clausen T. The protease state of the heat-shock protein DegP fromEscherichia coli Acta Crystallographica Section a Foundations of Crystallography. 63: s120-s120. DOI: 10.1107/S0108767307097413  0.705
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