Year |
Citation |
Score |
2024 |
Wu H, Murray J, Ishisoko N, Frommlet A, Deshmukh G, DiPasquale A, Mulvihill MM, Zhang D, Quinn JG, Blake RA, Fairbrother WJ, Fuhrmann J. Potency-Enhanced Peptidomimetic VHL Ligands with Improved Oral Bioavailability. Journal of Medicinal Chemistry. PMID 38809766 DOI: 10.1021/acs.jmedchem.3c02203 |
0.303 |
|
2020 |
Bashore C, Jaishankar P, Skelton NJ, Fuhrmann J, Hearn BR, Liu PS, Renslo AR, Dueber EC. Cyanopyrrolidine Inhibitors of Ubiquitin Specific Protease 7 Mediate Desulfhydration of the Active-Site Cysteine. Acs Chemical Biology. PMID 32302100 DOI: 10.1021/Acschembio.0C00031 |
0.444 |
|
2017 |
Brust R, Lin H, Fuhrmann J, Asteian A, Kamenecka TM, Kojetin DJ. Modification of the Orthosteric PPARγ Covalent Antagonist Scaffold Yields an Improved Dual-Site Allosteric Inhibitor. Acs Chemical Biology. PMID 28165718 DOI: 10.1021/Acschembio.6B01015 |
0.319 |
|
2016 |
Hughes TS, Shang J, Brust R, de Vera IM, Fuhrmann J, Ruiz C, Cameron MD, Kamenecka TM, Kojetin DJ. Probing the Complex Binding Modes of the PPARγ Partial Agonist 2-chloro-N-(3-chloro-4-((5-chlorobenzo[d]thiazol-2-yl)thio)phenyl)-4-(trifluoromethyl)benzenesulfonamide (T2384) to Orthosteric and Allosteric Sites with NMR Spectroscopy. Journal of Medicinal Chemistry. PMID 27783520 DOI: 10.1021/Acs.Jmedchem.6B01340 |
0.318 |
|
2016 |
Fuhrmann J, Subramanian V, Kojetin DJ, Thompson PR. Activity-Based Profiling Reveals a Regulatory Link between Oxidative Stress and Protein Arginine Phosphorylation. Cell Chemical Biology. PMID 27524296 DOI: 10.1016/J.Chembiol.2016.07.008 |
0.706 |
|
2015 |
Fuhrmann J, Thompson PR. Protein Arginine Methylation and Citrullination in Epigenetic Regulation. Acs Chemical Biology. PMID 26686581 DOI: 10.1021/Acschembio.5B00942 |
0.56 |
|
2015 |
Fuhrmann J, Subramanian V, Thompson PR. Synthesis and Use of a Phosphonate Amidine to Generate an Anti-Phosphoarginine-Specific Antibody. Angewandte Chemie (International Ed. in English). PMID 26458230 DOI: 10.1002/Anie.201506737 |
0.577 |
|
2015 |
Fuhrmann J, Clancy KW, Thompson PR. Chemical Biology of Protein Arginine Modifications in Epigenetic Regulation. Chemical Reviews. 115: 5413-61. PMID 25970731 DOI: 10.1021/Acs.Chemrev.5B00003 |
0.551 |
|
2015 |
Slade DJ, Fang P, Dreyton CJ, Zhang Y, Fuhrmann J, Rempel D, Bax BD, Coonrod SA, Lewis HD, Guo M, Gross ML, Thompson PR. Protein arginine deiminase 2 binds calcium in an ordered fashion: implications for inhibitor design. Acs Chemical Biology. 10: 1043-53. PMID 25621824 DOI: 10.1021/Cb500933J |
0.694 |
|
2014 |
Schmidt A, Trentini DB, Spiess S, Fuhrmann J, Ammerer G, Mechtler K, Clausen T. Quantitative Phosphoproteomics Reveals the Role of Protein Arginine Phosphorylation in the Bacterial Stress Response. Molecular & Cellular Proteomics : McP. 13: 537-550. PMID 33498137 DOI: 10.1074/mcp.M113.032292 |
0.775 |
|
2014 |
Wang M, Fuhrmann J, Thompson PR. Protein arginine methyltransferase 5 catalyzes substrate dimethylation in a distributive fashion. Biochemistry. 53: 7884-92. PMID 25485739 DOI: 10.1021/Bi501279G |
0.591 |
|
2014 |
Trentini DB, Fuhrmann J, Mechtler K, Clausen T. Chasing Phosphoarginine Proteins: Development of a Selective Enrichment Method Using a Phosphatase Trap. Molecular & Cellular Proteomics : McP. 13: 1953-64. PMID 24825175 DOI: 10.1074/Mcp.O113.035790 |
0.736 |
|
2014 |
Schmidt A, Trentini DB, Spiess S, Fuhrmann J, Ammerer G, Mechtler K, Clausen T. Quantitative phosphoproteomics reveals the role of protein arginine phosphorylation in the bacterial stress response. Molecular & Cellular Proteomics : McP. 13: 537-50. PMID 24263382 DOI: 10.1074/Mcp.M113.032292 |
0.715 |
|
2014 |
Slade DJ, Subramanian V, Fuhrmann J, Thompson PR. Chemical and biological methods to detect post-translational modifications of arginine. Biopolymers. 101: 133-43. PMID 23576281 DOI: 10.1002/Bip.22256 |
0.736 |
|
2013 |
Fuhrmann J, Subramanian V, Thompson PR. Targeting the arginine phosphatase YwlE with a catalytic redox-based inhibitor. Acs Chemical Biology. 8: 2024-32. PMID 23838530 DOI: 10.1021/Cb4001469 |
0.597 |
|
2013 |
Fuhrmann J, Mierzwa B, Trentini DB, Spiess S, Lehner A, Charpentier E, Clausen T. Structural basis for recognizing phosphoarginine and evolving residue-specific protein phosphatases in gram-positive bacteria. Cell Reports. 3: 1832-9. PMID 23770242 DOI: 10.1016/J.Celrep.2013.05.023 |
0.73 |
|
2009 |
Fuhrmann J, Schmidt A, Spiess S, Lehner A, Turgay K, Mechtler K, Charpentier E, Clausen T. McsB is a protein arginine kinase that phosphorylates and inhibits the heat-shock regulator CtsR. Science (New York, N.Y.). 324: 1323-7. PMID 19498169 DOI: 10.1126/Science.1170088 |
0.77 |
|
2007 |
Krojer T, Sawa J, Fuhrmann J, Gazda L, Kirk R, Kurt J, Nussbaumer B, Schmidt B, Clausen T. The protease state of the heat-shock protein DegP fromEscherichia coli Acta Crystallographica Section a Foundations of Crystallography. 63: s120-s120. DOI: 10.1107/S0108767307097413 |
0.705 |
|
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