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Stephen D. Fried, Ph.D - Publications

Affiliations: 
2018- Chemistry Johns Hopkins University, Baltimore, MD 
Area:
Biophysics, Chemical and Synthetic Biology
Website:
http://www.mrc-lmb.cam.ac.uk/sfried/
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28 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Wu Y, Fried SD, Boxer SG. A Preorganized Electric Field Leads to Minimal Geometrical Reorientation in the Catalytic Reaction of Ketosteroid Isomerase. Journal of the American Chemical Society. PMID 32378409 DOI: 10.1021/Jacs.0C00383  0.752
2020 Cervettini D, Tang S, Fried SD, Willis JCW, Funke LFH, Colwell LJ, Chin JW. Rapid discovery and evolution of orthogonal aminoacyl-tRNA synthetase-tRNA pairs. Nature Biotechnology. PMID 32284585 DOI: 10.1038/S41587-020-0479-2  0.744
2019 Saggu M, Fried SD, Boxer SG. Local and Global Electric Field Asymmetry in Photosynthetic Reaction Centers. The Journal of Physical Chemistry. B. PMID 30668130 DOI: 10.1021/Acs.Jpcb.8B11458  0.537
2019 Fried SD, Elliott TS, Wagner M, Carell T, Chin JW. The Genetic Code is Read by an Idiosyncratic and Highly-Connected Decoding Network Biophysical Journal. 116: 360a-361a. DOI: 10.1016/J.Bpj.2018.11.1963  0.665
2018 Schmied WH, Tnimov Z, Uttamapinant C, Rae CD, Fried SD, Chin JW. Controlling orthogonal ribosome subunit interactions enables evolution of new function. Nature. PMID 30518861 DOI: 10.1038/S41586-018-0773-Z  0.716
2017 Wang L, Fried SD, Markland TE. Proton Network Flexibility Enables Robustness and Large Electric Fields in the Ketosteroid Isomerase Active Site. The Journal of Physical Chemistry. B. PMID 28915043 DOI: 10.1021/Acs.Jpcb.7B06985  0.405
2017 Fried SD, Boxer SG. Electric Fields and Enzyme Catalysis. Annual Review of Biochemistry. PMID 28375745 DOI: 10.1146/Annurev-Biochem-061516-044432  0.566
2016 Elliott TS, Bianco A, Townsley FM, Fried SD, Chin JW. Tagging and Enriching Proteins Enables Cell-Specific Proteomics. Cell Chemical Biology. 23: 805-15. PMID 27447048 DOI: 10.1016/J.Chembiol.2016.05.018  0.733
2015 Fried SD, Schmied WH, Uttamapinant C, Chin JW. Ribosome Subunit Stapling for Orthogonal Translation in E.  coli. Angewandte Chemie (Weinheim An Der Bergstrasse, Germany). 127: 12982-12985. PMID 27570300 DOI: 10.1002/ange.201506311  0.776
2015 Wu Y, Fried SD, Boxer SG. Dissecting Proton Delocalization in an Enzyme's Hydrogen Bond Network with Unnatural Amino Acids. Biochemistry. PMID 26571340 DOI: 10.1021/Acs.Biochem.5B00958  0.739
2015 Fried SD, Schmied WH, Uttamapinant C, Chin JW. Ribosome Subunit Stapling for Orthogonal Translation in E. coli. Angewandte Chemie (International Ed. in English). 54: 12791-4. PMID 26465656 DOI: 10.1002/Anie.201506311  0.774
2015 Fried SD, Boxer SG. BIOPHYSICS. Response to Comments on "Extreme electric fields power catalysis in the active site of ketosteroid isomerase". Science (New York, N.Y.). 349: 936. PMID 26315428 DOI: 10.1126/Science.Aab1627  0.526
2015 Fried SD, Boxer SG. Measuring electric fields and noncovalent interactions using the vibrational stark effect. Accounts of Chemical Research. 48: 998-1006. PMID 25799082 DOI: 10.1021/Ar500464J  0.549
2015 Fried SD, Schmied WH, Uttamapinant C, Chin JW. Ribosome Subunit Stapling for Orthogonal Translation in E. coli Angewandte Chemie - International Edition. DOI: 10.1002/anie.201506311  0.749
2014 Fried SD, Bagchi S, Boxer SG. Extreme electric fields power catalysis in the active site of ketosteroid isomerase. Science (New York, N.Y.). 346: 1510-4. PMID 25525245 DOI: 10.1126/Science.1259802  0.675
2014 Wang L, Fried SD, Boxer SG, Markland TE. Quantum delocalization of protons in the hydrogen-bond network of an enzyme active site. Proceedings of the National Academy of Sciences of the United States of America. 111: 18454-9. PMID 25503367 DOI: 10.1073/Pnas.1417923111  0.536
2014 Wang L, Fried SD, Wu Y, Boxer SG, Markland TE. Quantum Delocalization of Protons in the Ketosteroid Isomerase Active Site Biophysical Journal. 106: 589a. DOI: 10.1016/J.Bpj.2013.11.3263  0.741
2014 Fried SD, Wang L, Boxer SG, Pande VS. Calculations of the Electric Field in Solutions and Proteins with Polarizable Force Fields Biophysical Journal. 106: 403a. DOI: 10.1016/J.Bpj.2013.11.2271  0.556
2013 Fried SD, Wang LP, Boxer SG, Ren P, Pande VS. Calculations of the electric fields in liquid solutions. The Journal of Physical Chemistry. B. 117: 16236-48. PMID 24304155 DOI: 10.1021/Jp410720Y  0.541
2013 Fried SD, Boxer SG. Thermodynamic framework for identifying free energy inventories of enzyme catalytic cycles. Proceedings of the National Academy of Sciences of the United States of America. 110: 12271-6. PMID 23840058 DOI: 10.1073/Pnas.1310964110  0.517
2013 Fried SD, Bagchi S, Boxer SG. Measuring electrostatic fields in both hydrogen-bonding and non-hydrogen-bonding environments using carbonyl vibrational probes. Journal of the American Chemical Society. 135: 11181-92. PMID 23808481 DOI: 10.1021/Ja403917Z  0.716
2013 Sigala PA, Fafarman AT, Schwans JP, Fried SD, Fenn TD, Caaveiro JM, Pybus B, Ringe D, Petsko GA, Boxer SG, Herschlag D. Quantitative dissection of hydrogen bond-mediated proton transfer in the ketosteroid isomerase active site. Proceedings of the National Academy of Sciences of the United States of America. 110: E2552-61. PMID 23798390 DOI: 10.1073/Pnas.1302191110  0.542
2013 Boxer S, Bagchi S, Fried SD, Levinson N, Saggu M, Xu L. Vibrational Stark Spectroscopy Directly Probes Electric Fields in Proteins Biophysical Journal. 104: 355a. DOI: 10.1016/J.Bpj.2012.11.1970  0.743
2013 Fried SD, Bagchi S, Boxer SG. Vibrational Stark Effects in the Active Site of Ketosteroid Isomerase Point to Large Electric Fields Driving Chemical Catalysis Biophysical Journal. 104: 205a. DOI: 10.1016/J.Bpj.2012.11.1157  0.678
2012 Bagchi S, Fried SD, Boxer SG. A solvatochromic model calibrates nitriles' vibrational frequencies to electrostatic fields. Journal of the American Chemical Society. 134: 10373-6. PMID 22694663 DOI: 10.1021/Ja303895K  0.664
2012 Levinson NM, Fried SD, Boxer SG. Solvent-induced infrared frequency shifts in aromatic nitriles are quantitatively described by the vibrational Stark effect. The Journal of Physical Chemistry. B. 116: 10470-6. PMID 22448878 DOI: 10.1021/Jp301054E  0.669
2012 Fried SD, Boxer SG. Evaluation of the energetics of the concerted acid-base mechanism in enzymatic catalysis: the case of ketosteroid isomerase. The Journal of Physical Chemistry. B. 116: 690-7. PMID 22148842 DOI: 10.1021/Jp210544W  0.538
2007 Rosenthal J, Chng LL, Fried SD, Nocera DG. Stereochemical control of H2O2 dismutation by Hangman porphyrins. Chemical Communications (Cambridge, England). 2642-4. PMID 17579765 DOI: 10.1039/B616884A  0.424
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