R Bendayan - Publications

Affiliations: 
University of Toronto, Toronto, ON, Canada 
Area:
Pharmacy, Public Health

76 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Huang C, Hoque MT, Qu QR, Henderson J, Bendayan R. Antiretroviral drug dolutegravir induces inflammation at the mouse brain barriers. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 38: e23790. PMID 38982638 DOI: 10.1096/fj.202400558R  0.337
2023 Huang C, Hoque T, Bendayan R. Antiretroviral drugs efavirenz, dolutegravir and bictegravir dysregulate blood-brain barrier integrity and function. Frontiers in Pharmacology. 14: 1118580. PMID 36969875 DOI: 10.3389/fphar.2023.1118580  0.474
2022 Nwabufo CK, Bendayan R. Pharmacokinetic considerations to optimize clinical outcomes for COVID-19 drugs. Trends in Pharmacological Sciences. 43: 1041-1054. PMID 36374805 DOI: 10.1016/j.tips.2022.09.005  0.326
2022 Zamek-Gliszczynski MJ, Sangha V, Shen H, Feng B, Wittwer MB, Varma MVS, Liang X, Sugiyama Y, Zhang L, Bendayan R. Transporters in drug development: International transporter consortium update on emerging transporters of clinical importance. Clinical Pharmacology and Therapeutics. PMID 35561119 DOI: 10.1002/cpt.2644  0.38
2021 Gilmore JC, Hoque MT, Dai W, Mohan H, Dunk C, Serghides L, Bendayan R. Interaction between dolutegravir and folate transporters and receptor in human and rodent placenta. Ebiomedicine. 75: 103771. PMID 34954655 DOI: 10.1016/j.ebiom.2021.103771  0.348
2021 Whyte-Allman SK, Kaul R, Bendayan R. Regulation of ABC Drug Efflux Transporters in Human T-Cells Exposed to an HIV Pseudotype. Frontiers in Pharmacology. 12: 711999. PMID 34421607 DOI: 10.3389/fphar.2021.711999  0.475
2021 Gilmore JC, Zhang G, Cameron DW, Serghides L, Bendayan R. Impact of in utero antiretroviral drug exposure on expression of membrane-associated transporters in mouse placenta and fetal brain. Aids (London, England). PMID 34175869 DOI: 10.1097/QAD.0000000000003009  0.443
2021 Hoque TMD, Cattin A, Whyte-Allman SK, Winchester L, Fletcher CV, Routy JP, Ancuta P, Bendayan R. Antiretroviral Drug Transporters and Metabolic Enzymes in Circulating Monocytes and Monocyte-Derived Macrophages of ART-Treated People Living With HIV and HIV-Uninfected Individuals. Journal of Acquired Immune Deficiency Syndromes (1999). 87: 1093-1101. PMID 34153016 DOI: 10.1097/QAI.0000000000002682  0.498
2020 Gilmore JC, Serghides L, Bendayan R. Differential effects of antiretroviral drug toxicity in male versus female children who are HIV-exposed but uninfected. Aids (London, England). PMID 33048885 DOI: 10.1097/QAD.0000000000002707  0.418
2020 Whyte-Allman SK, Bendayan R. HIV-1 Sanctuary Sites-the Role of Membrane-Associated Drug Transporters and Drug Metabolic Enzymes. The Aaps Journal. 22: 118. PMID 32875457 DOI: 10.1208/s12248-020-00498-1  0.491
2020 Omeragic A, Kayode O, Hoque MT, Bendayan R. Potential pharmacological approaches for the treatment of HIV-1 associated neurocognitive disorders. Fluids and Barriers of the Cns. 17: 42. PMID 32650790 DOI: 10.1186/s12987-020-00204-5  0.406
2020 Whyte-Allman SK, Hoque MT, Gilmore J, Kaul R, Routy JP, Bendayan R. Drug efflux transporters and metabolic enzymes in human circulating and testicular T-cell subsets: relevance to HIV pharmacotherapy. Aids (London, England). PMID 32310902 DOI: 10.1097/QAD.0000000000002548  0.411
2019 Omeragic A, Saikali MF, Currier S, Volsky DJ, Cummins CL, Bendayan R. Selective peroxisome proliferator-activated receptor-gamma modulator, INT131 exhibits anti-inflammatory effects in an EcoHIV mouse model. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 31907999 DOI: 10.1096/Fj.201901874R  0.34
2019 Omeragic A, Kara-Yacoubian N, Kelschenbach J, Sahin C, Cummins CL, Volsky DJ, Bendayan R. Peroxisome Proliferator-Activated Receptor-gamma agonists exhibit anti-inflammatory and antiviral effects in an EcoHIV mouse model. Scientific Reports. 9: 9428. PMID 31263138 DOI: 10.1038/S41598-019-45878-6  0.303
2017 Whyte-Allman SK, Hoque MT, Jenabian MA, Routy JP, Bendayan R. Xenobiotic Nuclear Receptors PXR and CAR Regulate Antiretroviral Drug Efflux Transporters at the Blood-Testis Barrier. The Journal of Pharmacology and Experimental Therapeutics. PMID 28970358 DOI: 10.1124/jpet.117.243584  0.368
2017 Omeragic A, Hoque MT, Choi UY, Bendayan R. Peroxisome proliferator-activated receptor-gamma: potential molecular therapeutic target for HIV-1-associated brain inflammation. Journal of Neuroinflammation. 14: 183. PMID 28886715 DOI: 10.1186/s12974-017-0957-8  0.391
2017 Jenabian MA, Costiniuk CT, Mehraj V, Ghazawi FM, Fromentin R, Brousseau J, Brassard P, Bélanger M, Ancuta P, Bendayan R, Chomont N, Routy JP. Immune tolerance properties of the testicular tissue as a viral sanctuary site in ART-treated HIV-infected adults. Aids (London, England). 30: 2777-2786. PMID 27677162 DOI: 10.1097/QAD.0000000000001282  0.331
2016 Alam C, Whyte-Allman SK, Omeragic A, Bendayan R. Role and modulation of drug transporters in HIV-1 therapy. Advanced Drug Delivery Reviews. PMID 27181050 DOI: 10.1016/j.addr.2016.05.001  0.512
2016 Huang Y, Hoque MT, Jenabian MA, Vyboh K, Whyte SK, Sheehan NL, Brassard P, Bélanger M, Chomont N, Fletcher CV, Routy JP, Bendayan R. Antiretroviral drug transporters and metabolic enzymes in human testicular tissue: potential contribution to HIV-1 sanctuary site. The Journal of Antimicrobial Chemotherapy. PMID 27076103 DOI: 10.1093/jac/dkw046  0.433
2016 Kis O, Sankaran-Walters S, Hoque MT, Walmsley SL, Dandekar S, Bendayan R. HIV-1 Alters Intestinal Expression of Drug Transporters and Metabolic Enzymes: Implications in Antiretroviral Drug Disposition. Antimicrobial Agents and Chemotherapy. PMID 26902756 DOI: 10.1128/Aac.02278-15  0.496
2015 Hoque MT, Shah A, More V, Miller DS, Bendayan R. In Vivo and Ex Vivo Regulation of Breast Cancer Resistant Protein (Bcrp) by Peroxisome Proliferator-Activated Receptor Alpha (Pparα) at the Blood-Brain Barrier. Journal of Neurochemistry. PMID 26465636 DOI: 10.1111/Jnc.13389  0.336
2015 Hoque MT, Kis O, De Rosa MF, Bendayan R. Raltegravir permeability across blood-tissue barriers and the potential role of drug efflux transporters. Antimicrobial Agents and Chemotherapy. 59: 2572-82. PMID 25691630 DOI: 10.1128/AAC.04594-14  0.335
2015 Banerjee N, Wu TR, Chio J, Kelly R, Stephenson KA, Forbes J, Allen C, Valliant JF, Bendayan R. (125)I-Labelled 2-Iodoestrone-3-sulfate: synthesis, characterization and OATP mediated transport studies in hormone dependent and independent breast cancer cells. Nuclear Medicine and Biology. 42: 274-82. PMID 25542669 DOI: 10.1016/J.Nucmedbio.2014.10.011  0.579
2014 Ashraf T, Kao A, Bendayan R. Functional expression of drug transporters in glial cells: potential role on drug delivery to the CNS. Advances in Pharmacology (San Diego, Calif.). 71: 45-111. PMID 25307214 DOI: 10.1016/bs.apha.2014.06.010  0.406
2014 Ashraf T, Jiang W, Hoque MT, Henderson J, Wu C, Bendayan R. Role of anti-inflammatory compounds in human immunodeficiency virus-1 glycoprotein120-mediated brain inflammation. Journal of Neuroinflammation. 11: 91. PMID 24884548 DOI: 10.1186/1742-2094-11-91  0.371
2014 Banerjee N, Miller N, Allen C, Bendayan R. Expression of membrane transporters and metabolic enzymes involved in estrone-3-sulphate disposition in human breast tumour tissues. Breast Cancer Research and Treatment. 145: 647-61. PMID 24831777 DOI: 10.1007/S10549-014-2990-Y  0.584
2014 Robillard KR, Hoque MT, Bendayan R. Expression of ATP-binding cassette membrane transporters in a HIV-1 transgenic rat model. Biochemical and Biophysical Research Communications. 444: 531-6. PMID 24472536 DOI: 10.1016/J.Bbrc.2014.01.092  0.823
2014 Robillard KR, Chan GN, Zhang G, la Porte C, Cameron W, Bendayan R. Role of P-glycoprotein in the distribution of the HIV protease inhibitor atazanavir in the brain and male genital tract. Antimicrobial Agents and Chemotherapy. 58: 1713-22. PMID 24379203 DOI: 10.1128/Aac.02031-13  0.781
2014 Ashraf T, Robillard K, Chan GN, Bendayan R. Role of CNS transporters in the pharmacotherapy of HIV-1 associated neurological disorders. Current Pharmaceutical Design. 20: 1543-63. PMID 23789949 DOI: 10.2174/13816128113199990464  0.81
2013 De Rosa MF, Robillard KR, Kim CJ, Hoque MT, Kandel G, Kovacs C, Kaul R, Bendayan R. Expression of membrane drug efflux transporters in the sigmoid colon of HIV-infected and uninfected men. Journal of Clinical Pharmacology. 53: 934-45. PMID 23856938 DOI: 10.1002/Jcph.132  0.822
2013 Chan GNY, Patel R, Cummins CL, Bendayan R. Induction of P-glycoprotein by antiretroviral drugs in human brain microvessel endothelial cells Antimicrobial Agents and Chemotherapy. 57: 4481-4488. PMID 23836171 DOI: 10.1128/Aac.00486-13  0.439
2013 Chan GN, Saldivia V, Yang Y, Pang H, de Lannoy I, Bendayan R. In vivo induction of P-glycoprotein expression at the mouse blood-brain barrier: an intracerebral microdialysis study. Journal of Neurochemistry. 127: 342-52. PMID 23777437 DOI: 10.1111/jnc.12344  0.61
2013 Chan GN, Hoque MT, Bendayan R. Role of nuclear receptors in the regulation of drug transporters in the brain. Trends in Pharmacological Sciences. 34: 361-72. PMID 23769624 DOI: 10.1016/j.tips.2013.05.004  0.651
2013 Banerjee N, Fonge H, Mikhail A, Reilly RM, Bendayan R, Allen C. Estrone-3-sulphate, a potential novel ligand for targeting breast cancers. Plos One. 8: e64069. PMID 23717534 DOI: 10.1371/Journal.Pone.0064069  0.574
2013 Dallas S, Block ML, Thompson DM, Bonini MG, Ronaldson PT, Bendayan R, Miller DS. Microglial activation decreases retention of the protease inhibitor saquinavir: implications for HIV treatment. Journal of Neuroinflammation. 10: 58. PMID 23642074 DOI: 10.1186/1742-2094-10-58  0.437
2013 Kis O, Zastre JA, Hoque MT, Walmsley SL, Bendayan R. Role of drug efflux and uptake transporters in atazanavir intestinal permeability and drug-drug interactions. Pharmaceutical Research. 30: 1050-64. PMID 23224979 DOI: 10.1007/s11095-012-0942-y  0.448
2012 Ashraf T, Kis O, Banerjee N, Bendayan R. Drug transporters at brain barriers: expression and regulation by neurological disorders. Advances in Experimental Medicine and Biology. 763: 20-69. PMID 23397618  0.683
2012 Durk MR, Chan GN, Campos CR, Peart JC, Chow EC, Lee E, Cannon RE, Bendayan R, Miller DS, Pang KS. 1α,25-Dihydroxyvitamin D3-liganded vitamin D receptor increases expression and transport activity of P-glycoprotein in isolated rat brain capillaries and human and rat brain microvessel endothelial cells. Journal of Neurochemistry. 123: 944-53. PMID 23035695 DOI: 10.1111/Jnc.12041  0.571
2012 Banerjee N, Allen C, Bendayan R. Differential role of organic anion-transporting polypeptides in estrone-3-sulphate uptake by breast epithelial cells and breast cancer cells. The Journal of Pharmacology and Experimental Therapeutics. 342: 510-9. PMID 22588260 DOI: 10.1124/Jpet.112.192344  0.57
2012 Hoque MT, Robillard KR, Bendayan R. Regulation of breast cancer resistant protein by peroxisome proliferator-activated receptor α in human brain microvessel endothelial cells. Molecular Pharmacology. 81: 598-609. PMID 22266374 DOI: 10.1124/Mol.111.076745  0.771
2012 Robillard KR, Hoque T, Bendayan R. Expression of ATP-binding cassette membrane transporters in rodent and human sertoli cells: relevance to the permeability of antiretroviral therapy at the blood-testis barrier. The Journal of Pharmacology and Experimental Therapeutics. 340: 96-108. PMID 21990609 DOI: 10.1124/Jpet.111.186916  0.807
2011 Chan GN, Hoque MT, Cummins CL, Bendayan R. Regulation of P-glycoprotein by orphan nuclear receptors in human brain microvessel endothelial cells. Journal of Neurochemistry. 118: 163-75. PMID 21517853 DOI: 10.1111/J.1471-4159.2011.07288.X  0.599
2011 Di Risio M, Ballantyne PJ, Read SE, Bendayan R. "HIV isn't me…": HIV+ adolescents' experiences in a positive context of support and treatment. Aids Care. 23: 694-9. PMID 21390880 DOI: 10.1080/09540121.2010.532539  0.323
2011 Chan GN, Bendayan R. Molecular and functional characterization of P-glycoprotein in vitro. Methods in Molecular Biology (Clifton, N.J.). 686: 313-36. PMID 21082379 DOI: 10.1007/978-1-60761-938-3_15  0.614
2011 Dallas S, E Read S, King S, Koren G, Bendayan R. Pharmacokinetic interaction between zidovudine and trimethoprim/sulphamethoxazole in HIV-1 infected children. The Canadian Journal of Infectious Diseases = Journal Canadien Des Maladies Infectieuses. 11: 254-8. PMID 18159298 DOI: 10.1155/2000/640718  0.377
2010 Kis O, Zastre JA, Ramaswamy M, Bendayan R. pH dependence of organic anion-transporting polypeptide 2B1 in Caco-2 cells: Potential role in antiretroviral drug oral bioavailability and drug-drug interactions Journal of Pharmacology and Experimental Therapeutics. 334: 1009-1022. PMID 20507927 DOI: 10.1124/jpet.110.166314  0.386
2010 Kis O, Robillard K, Chan GN, Bendayan R. The complexities of antiretroviral drug-drug interactions: role of ABC and SLC transporters. Trends in Pharmacological Sciences. 31: 22-35. PMID 20004485 DOI: 10.1016/J.Tips.2009.10.001  0.796
2010 Wong HL, Chattopadhyay N, Wu XY, Bendayan R. Nanotechnology applications for improved delivery of antiretroviral drugs to the brain. Advanced Drug Delivery Reviews. 62: 503-17. PMID 19914319 DOI: 10.1016/J.Addr.2009.11.020  0.439
2009 Zastre JA, Chan GNY, Ronaldson PT, Ramaswamy M, Couraud PO, Romero IA, Weksler B, Bendayan M, Bendayan R. Up-regulation of p-glycoprotein by HIV protease inhibitors in a human brain microvessel endothelial cell line Journal of Neuroscience Research. 87: 1023-1036. PMID 18855943 DOI: 10.1002/jnr.21898  0.422
2008 Ronaldson PT, Persidsky Y, Bendayan R. Regulation of ABC membrane transporters in glial cells: relevance to the pharmacotherapy of brain HIV-1 infection. Glia. 56: 1711-35. PMID 18649402 DOI: 10.1002/Glia.20725  0.535
2008 Chattopadhyay N, Zastre J, Wong HL, Wu XY, Bendayan R. Solid lipid nanoparticles enhance the delivery of the HIV protease inhibitor, atazanavir, by a human brain endothelial cell line. Pharmaceutical Research. 25: 2262-71. PMID 18516666 DOI: 10.1007/S11095-008-9615-2  0.401
2008 Ronaldson PT, Bendayan R. HIV-1 viral envelope glycoprotein gp120 produces oxidative stress and regulates the functional expression of multidrug resistance protein-1 (Mrp1) in glial cells. Journal of Neurochemistry. 106: 1298-313. PMID 18485102 DOI: 10.1111/j.1471-4159.2008.05479.x  0.329
2007 Lee G, Babakhanian K, Ramaswamy M, Prat A, Wosik K, Bendayan R. Expression of the ATP-binding cassette membrane transporter, ABCG2, in human and rodent brain microvessel endothelial and glial cell culture systems. Pharmaceutical Research. 24: 1262-74. PMID 17380269 DOI: 10.1007/S11095-007-9244-1  0.301
2006 Bendayan R, Ronaldson PT, Gingras D, Bendayan M. In situ localization of P-glycoprotein (ABCB1) in human and rat brain Journal of Histochemistry and Cytochemistry. 54: 1159-1167. PMID 16801529 DOI: 10.1369/jhc.5A6870.2006  0.305
2006 Ronaldson PT, Bendayan R. HIV-1 viral envelope glycoprotein gp120 triggers an inflammatory response in cultured rat astrocytes and regulates the functional expression of P-glycoprotein. Molecular Pharmacology. 70: 1087-98. PMID 16790532 DOI: 10.1124/mol.106.025973  0.381
2006 Dallas S, Miller DS, Bendayan R. Multidrug resistance-associated proteins: expression and function in the central nervous system. Pharmacological Reviews. 58: 140-61. PMID 16714484 DOI: 10.1124/pr.58.2.3  0.346
2006 Furler MD, Einarson TR, Walmsley S, Millson M, Bendayan R. Longitudinal trends in antiretroviral use in a cohort of men and women in Ontario, Canada. Aids Patient Care and Stds. 20: 245-57. PMID 16623623 DOI: 10.1089/Apc.2006.20.245  0.776
2005 Lee G, Bendayan R. Functional expression and localization of P-glycoprotein in the central nervous system: relevance to the pathogenesis and treatment of neurological disorders. Pharmaceutical Research. 21: 1313-30. PMID 15359566 DOI: 10.1023/B:PHAM.0000036905.82914.8e  0.327
2004 Furler MD, Einarson TR, Walmsley S, Millson M, Bendayan R. Polypharmacy in HIV: impact of data source and gender on reported drug utilization. Aids Patient Care and Stds. 18: 568-86. PMID 15630785 DOI: 10.1089/Apc.2004.18.568  0.783
2004 Ronaldson PT, Lee G, Dallas S, Bendayan R. Involvement of P-glycoprotein in the transport of saquinavir and indinavir in rat brain microvessel endothelial and microglia cell lines. Pharmaceutical Research. 21: 811-8. PMID 15180339 DOI: 10.1023/B:PHAM.0000026433.27773.47  0.428
2004 Furler MD, Einarson TR, Millson M, Walmsley S, Bendayan R. Medicinal and recreational marijuana use by patients infected with HIV. Aids Patient Care and Stds. 18: 215-28. PMID 15142352 DOI: 10.1089/108729104323038892  0.77
2004 Dallas S, Ronaldson PT, Bendayan M, Bendayan R. Multidrug resistance protein 1-mediated transport of saquinavir by microglia. Neuroreport. 15: 1183-6. PMID 15129170 DOI: 10.1097/00001756-200405190-00020  0.397
2004 Dallas S, Schlichter L, Bendayan R. Multidrug resistance protein (MRP) 4- and MRP 5-mediated efflux of 9-(2-phosphonylmethoxyethyl)adenine by microglia Journal of Pharmacology and Experimental Therapeutics. 309: 1221-1229. PMID 14762102 DOI: 10.1124/jpet.103.063966  0.423
2003 Dallas S, Zhu X, Baruchel S, Schlichter L, Bendayan R. Functional expression of the multidrug resistance protein 1 in microglia Journal of Pharmacology and Experimental Therapeutics. 307: 282-290. PMID 12893836 DOI: 10.1124/jpet.103.054304  0.386
2003 Furler MD, Einarson TR, Walmsley S, Millson M, Bendayan R. Use of complementary and alternative medicine by HIV-infected outpatients in Ontario, Canada. Aids Patient Care and Stds. 17: 155-68. PMID 12737639 DOI: 10.1089/108729103321619764  0.773
2002 Lee G, Dallas S, Hong M, Bendayan R. Drug transporters in the central nervous system: brain barriers and brain parenchyma considerations. Pharmacological Reviews. 53: 569-96. PMID 11734619  0.392
2002 Ronaldson PT, Bendayan R. Renal Drug Transport and Drug-Drug Interactions Journal of Pharmacy Practice. 15: 490-503. DOI: 10.1177/089719002237667  0.35
2001 Lee G, Schlichter L, Bendayan M, Bendayan R. Functional expression of p-glycoprotein in rat brain microglia Journal of Pharmacology and Experimental Therapeutics. 299: 204-212. PMID 11561081  0.387
2000 Hong M, Schlichter L, Bendayan R. A Na+-dependent nucleoside transporter in microglia Journal of Pharmacology and Experimental Therapeutics. 292: 366-374. PMID 10604972  0.399
1999 Leung S, Bendayan R. Role of P-glycoprotein in the renal transport of dideoxynucleoside analog drugs. Canadian Journal of Physiology and Pharmacology. 77: 625-30. PMID 10543726  0.319
1999 LEUNG S, BENDAYAN R. Is P-glycoprotein (P-gp) involved in the renal tubular transport of nucleoside analog drugs (NADs)1 Clinical Pharmacology & Therapeutics. 65: 125-125. DOI: 10.1016/S0009-9236(99)80034-4  0.409
1999 Hong M, Schlichter L, Pennefather P, Bendayan R. Uptake properties of zidovudine (ZDV) by an HIV-I target brain parenchyma cell line Clinical Pharmacology and Therapeutics. 65: 125. DOI: 10.1016/S0009-9236(99)80031-9  0.458
1999 HONG M, SCHLICHTER L, PENNEFATHER P, BENDAYAN R. Uptake properties of zidovudine (ZDV) by an HIV-I target brain parenchyma cell line Clinical Pharmacology & Therapeutics. 65: 125-125. DOI: 10.1016/S0009-9236(99)80031-9  0.355
1998 Robertson-Dallas S, Read SE, Bendayan R. New drug interactions with zidovudine. Pharmacotherapy. 17: 1198-209. PMID 9399602  0.466
1997 Bendayan R. Renal drug transport: a review. Pharmacotherapy. 16: 971-85. PMID 8947968  0.309
1993 Chow R, Chin T, Fong IW, Bendayan R. Medication use patterns in HIV-positive patients. The Canadian Journal of Hospital Pharmacy. 46: 171-5. PMID 10128360  0.436
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