Year |
Citation |
Score |
2014 |
Perez HL, Junnotula V, Knecht D, Nie H, Sanchez Y, Boehm JC, Booth-Genthe C, Yan H, Davis R, Callahan JF. Analytical approaches for quantification of a Nrf2 pathway activator: overcoming bioanalytical challenges to support a toxicity study. The Analyst. 139: 1902-12. PMID 24563904 DOI: 10.1039/C3An02216A |
0.482 |
|
2014 |
Shen X, Rajapakse A, Gallazzi F, Junnotula V, Fuchs-Knotts T, Glaser R, Gates KS. Isotopic labeling experiments that elucidate the mechanism of DNA strand cleavage by the hypoxia-selective antitumor agent 1,2,4-benzotriazine 1,4-di-N-oxide. Chemical Research in Toxicology. 27: 111-8. PMID 24328261 DOI: 10.1021/Tx400356Y |
0.738 |
|
2010 |
Junnotula V, Rajapakse A, Arbillaga L, de Cerain AL, Solano B, Villar R, Monge A, Gates KS. DNA strand cleaving properties and hypoxia-selective cytotoxicity of 7-chloro-2-thienylcarbonyl-3-trifluoromethylquinoxaline 1,4-dioxide. Bioorganic & Medicinal Chemistry. 18: 3125-32. PMID 20371184 DOI: 10.1016/J.Bmc.2010.03.042 |
0.676 |
|
2009 |
Junnotula V, Sarkar U, Sinha S, Gates KS. Initiation of DNA strand cleavage by 1,2,4-benzotriazine 1,4-dioxide antitumor agents: mechanistic insight from studies of 3-methyl-1,2,4-benzotriazine 1,4-dioxide. Journal of the American Chemical Society. 131: 1015-24. PMID 19117394 DOI: 10.1021/Ja8049645 |
0.587 |
|
2007 |
Solano B, Junnotula V, Marín A, Villar R, Burguete A, Vicente E, Pérez-Silanes S, Aldana I, Monge A, Dutta S, Sarkar U, Gates KS. Synthesis and biological evaluation of new 2-arylcarbonyl-3-trifluoromethylquinoxaline 1,4-di-N-oxide derivatives and their reduced analogues. Journal of Medicinal Chemistry. 50: 5485-92. PMID 17910426 DOI: 10.1021/Jm0703993 |
0.683 |
|
2007 |
Chowdhury G, Junnotula V, Daniels JS, Greenberg MM, Gates KS. DNA strand damage product analysis provides evidence that the tumor cell-specific cytotoxin tirapazamine produces hydroxyl radical and acts as a surrogate for O(2). Journal of the American Chemical Society. 129: 12870-7. PMID 17900117 DOI: 10.1021/Ja074432M |
0.707 |
|
2006 |
Junnotula V, Sarkar U, Barnes CL, Thallapally PK, Gates KS. Crystal structures of 3-methyl-1,2,4-benzotriazine 1-oxide and 2-oxide Journal of Chemical Crystallography. 36: 557-561. DOI: 10.1007/S10870-006-9099-Z |
0.672 |
|
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