Year |
Citation |
Score |
2018 |
Shen X, Laber CH, Sarkar U, Gallazzi F, Johnson KM, Mahieu NG, Hillebrand R, Fuchs-Knotts T, Barnes CL, Baker GA, Gates KS. Exploiting the inherent photophysical properties of the major tirapazamine metabolite in the development of profluorescent substrates for enzymes that catalyze the bioreductive activation of hypoxia-selective anticancer prodrugs. The Journal of Organic Chemistry. PMID 29461834 DOI: 10.1021/Acs.Joc.7B03035 |
0.63 |
|
2017 |
Sarkar U, Hillebrand R, Johnson KM, Cummings AH, Phung NL, Rajapakse A, Zhou H, Willis JR, Barnes CL, Gates KS. Application of Suzuki-Miyaura and Buchwald-Hartwig Cross-coupling Reactions to the Preparation of Substituted 1,2,4-Benzotriazine 1-Oxides Related to the Antitumor Agent Tirapazamine. Journal of Heterocyclic Chemistry. 54: 155-160. PMID 28439141 DOI: 10.1002/Jhet.2559 |
0.626 |
|
2013 |
Rajapakse A, Linder C, Morrison RD, Sarkar U, Leigh ND, Barnes CL, Daniels JS, Gates KS. Enzymatic conversion of 6-nitroquinoline to the fluorophore 6-aminoquinoline selectively under hypoxic conditions. Chemical Research in Toxicology. 26: 555-63. PMID 23488987 DOI: 10.1021/Tx300483Z |
0.62 |
|
2012 |
Chowdhury G, Sarkar U, Pullen S, Wilson WR, Rajapakse A, Fuchs-Knotts T, Gates KS. DNA strand cleavage by the phenazine di-N-oxide natural product myxin under both aerobic and anaerobic conditions. Chemical Research in Toxicology. 25: 197-206. PMID 22084973 DOI: 10.1021/Tx2004213 |
0.756 |
|
2010 |
Sarkar U, Glaser R, Parsons ZD, Barnes CL, Gates KS. Synthesis, Crystal Structure, and Rotational Energy Profile of 3-Cyclopropyl-1,2,4-benzotriazine 1,4-Di-N-oxide. Journal of Chemical Crystallography. 40: 624-629. PMID 22294856 DOI: 10.1007/S10870-010-9707-9 |
0.669 |
|
2010 |
Rajapakse A, Sarkar U, Linder C, Daniels JS, Gates KS. Abstract 4558: 6-Nitroquinoline as a metabolically-activated probe for direct fluorescence detection of hypoxia Cancer Research. 70: 4558-4558. DOI: 10.1158/1538-7445.Am10-4558 |
0.572 |
|
2009 |
Junnotula V, Sarkar U, Sinha S, Gates KS. Initiation of DNA strand cleavage by 1,2,4-benzotriazine 1,4-dioxide antitumor agents: mechanistic insight from studies of 3-methyl-1,2,4-benzotriazine 1,4-dioxide. Journal of the American Chemical Society. 131: 1015-24. PMID 19117394 DOI: 10.1021/Ja8049645 |
0.628 |
|
2008 |
Glaser R, Sui Y, Sarkar U, Gates KS. Electronic structures and spin topologies of gamma-picoliniumyl radicals. A study of the homolysis of N-methyl-gamma-picolinium and of benzo-, dibenzo-, and naphthoannulated analogs. The Journal of Physical Chemistry. A. 112: 4800-14. PMID 18494451 DOI: 10.1021/Jp8011987 |
0.615 |
|
2007 |
Sui Y, Glaser R, Sarkar U, Gates K. Stabilities and Spin Distributions of Benzannulated Benzyl Radicals. Journal of Chemical Theory and Computation. 3: 1091-9. PMID 26627428 DOI: 10.1021/Ct700051J |
0.533 |
|
2007 |
Solano B, Junnotula V, Marín A, Villar R, Burguete A, Vicente E, Pérez-Silanes S, Aldana I, Monge A, Dutta S, Sarkar U, Gates KS. Synthesis and biological evaluation of new 2-arylcarbonyl-3-trifluoromethylquinoxaline 1,4-di-N-oxide derivatives and their reduced analogues. Journal of Medicinal Chemistry. 50: 5485-92. PMID 17910426 DOI: 10.1021/Jm0703993 |
0.719 |
|
2006 |
Junnotula V, Sarkar U, Barnes CL, Thallapally PK, Gates KS. Crystal structures of 3-methyl-1,2,4-benzotriazine 1-oxide and 2-oxide Journal of Chemical Crystallography. 36: 557-561. DOI: 10.1007/S10870-006-9099-Z |
0.71 |
|
2005 |
Sarkar U, Roy DR, Chattaraj PK, Parthasarathi R, Padmanabhan J, Subramanian V. A conceptual DFT approach towards analysing toxicity Journal of Chemical Sciences. 117: 599-612. DOI: 10.1007/Bf02708367 |
0.354 |
|
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