Peter Brzezinski, Ph.D - Publications

Affiliations: 
Biochemistry and Biophysics Stockholm University, Stockholm, Stockholms län, Sweden 
Area:
structure and function of membrane proteins involved in electron and proton transport
Website:
http://www.dbb.su.se/en/?p=researchgroup&id=23

160 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Berg J, Liu J, Svahn E, Ferguson-Miller S, Brzezinski P. Structural changes at the surface of cytochrome c oxidase alter the proton-pumping stoichiometry. Biochimica Et Biophysica Acta. Bioenergetics. 148116. PMID 31733183 DOI: 10.1016/j.bbabio.2019.148116  0.56
2019 Vilhjálmsdóttir J, Albertsson I, Blomberg MRA, Ädelroth P, Brzezinski P. Proton transfer in uncoupled variants of cytochrome c oxidase. Febs Letters. PMID 31725900 DOI: 10.1002/1873-3468.13679  0.72
2019 Graf S, Brzezinski P, von Ballmoos C. The proton pumping bo oxidase from Vitreoscilla. Scientific Reports. 9: 4766. PMID 30886219 DOI: 10.1038/s41598-019-40723-2  0.68
2018 Wiseman B, Nitharwal RG, Fedotovskaya O, Schäfer J, Guo H, Kuang Q, Benlekbir S, Sjöstrand D, Ädelroth P, Rubinstein JL, Brzezinski P, Högbom M. Structure of a functional obligate complex IIIIV respiratory supercomplex from Mycobacterium smegmatis. Nature Structural & Molecular Biology. 25: 1128-1136. PMID 30518849 DOI: 10.1038/s41594-018-0160-3  0.72
2018 Smirnova IA, Ädelroth P, Brzezinski P. Extraction and liposome reconstitution of membrane proteins with their native lipids without the use of detergents. Scientific Reports. 8: 14950. PMID 30297885 DOI: 10.1038/s41598-018-33208-1  0.72
2018 Schäfer J, Dawitz H, Ott M, Ädelroth P, Brzezinski P. Regulation of cytochrome c oxidase activity by modulation of the catalytic site. Scientific Reports. 8: 11397. PMID 30061583 DOI: 10.1038/s41598-018-29567-4  0.72
2018 Lundgren CAK, Sjöstrand D, Biner O, Bennett M, Rudling A, Johansson AL, Brzezinski P, Carlsson J, von Ballmoos C, Högbom M. Scavenging of superoxide by a membrane-bound superoxide oxidase. Nature Chemical Biology. PMID 29915379 DOI: 10.1038/s41589-018-0072-x  0.68
2018 Vilhjálmsdóttir J, Gennis RB, Brzezinski P. The electron distribution in the "activated" state of cytochrome c oxidase. Scientific Reports. 8: 7502. PMID 29760451 DOI: 10.1038/s41598-018-25779-w  1
2018 Schäfer J, Dawitz H, Ott M, Ädelroth P, Brzezinski P. Structural and functional heterogeneity of cytochrome c oxidase in S. cerevisiae. Biochimica Et Biophysica Acta. PMID 29746825 DOI: 10.1016/j.bbabio.2018.05.004  0.72
2018 Zhou S, Pettersson P, Huang J, Sjöholm J, Sjöstrand D, Pomès R, Högbom M, Brzezinski P, Mäler L, Ädelroth P. Solution NMR structure of yeast Rcf1, a protein involved in respiratory supercomplex formation. Proceedings of the National Academy of Sciences of the United States of America. PMID 29507228 DOI: 10.1073/pnas.1712061115  0.72
2017 Poiana F, von Ballmoos C, Gonska N, Blomberg MRA, Ädelroth P, Brzezinski P. Splitting of the O-O bond at the heme-copper catalytic site of respiratory oxidases. Science Advances. 3: e1700279. PMID 28630929 DOI: 10.1126/sciadv.1700279  0.72
2017 Sjöholm J, Bergstrand J, Nilsson T, Šachl R, Ballmoos CV, Widengren J, Brzezinski P. The lateral distance between a proton pump and ATP synthase determines the ATP-synthesis rate. Scientific Reports. 7: 2926. PMID 28592883 DOI: 10.1038/s41598-017-02836-4  0.36
2016 Björck M, Zhou S, Lundin CR, Ott M, Ädelroth P, Brzezinski P. Reaction of S. cerevisiae mitochondria with ligands: Kinetics of CO and O2 binding to flavohemoglobin and cytochrome c oxidase. Biochimica Et Biophysica Acta. PMID 27871795 DOI: 10.1016/j.bbabio.2016.11.009  0.72
2016 Graf S, Fedotovskaya O, Kao WC, Hunte C, Ädelroth P, Bott M, von Ballmoos C, Brzezinski P. Rapid Electron Transfer within the III-IV Supercomplex in Corynebacterium glutamicum. Scientific Reports. 6: 34098. PMID 27682138 DOI: 10.1038/srep34098  0.72
2016 Smirnova IA, Sjöstrand D, Li F, Björck M, Schäfer J, Östbye H, Högbom M, von Ballmoos C, Lander G, Ädelroth P, Brzezinski P. Isolation of yeast complex IV in native lipid nanodiscs. Biochimica Et Biophysica Acta. PMID 27620332 DOI: 10.1016/j.bbamem.2016.09.004  1
2016 Rydström Lundin C, von Ballmoos C, Ott M, Ädelroth P, Brzezinski P. Regulatory role of the respiratory supercomplex factors in Saccharomyces cerevisiae. Proceedings of the National Academy of Sciences of the United States of America. PMID 27432958 DOI: 10.1073/pnas.1601196113  0.72
2016 Xu L, Öjemyr LN, Bergstrand J, Brzezinski P, Widengren J. Protonation Dynamics on Lipid Nanodiscs: Influence of the Membrane Surface Area and External Buffers. Biophysical Journal. 110: 1993-2003. PMID 27166807 DOI: 10.1016/j.bpj.2016.03.035  0.52
2016 Nilsson T, Lundin CR, Nordlund G, Ädelroth P, von Ballmoos C, Brzezinski P. Lipid-mediated Protein-protein Interactions Modulate Respiration-driven ATP Synthesis. Scientific Reports. 6: 24113. PMID 27063297 DOI: 10.1038/srep24113  0.72
2016 Lerche M, Dian C, Round A, Lönneborg R, Brzezinski P, Leonard GA. The solution configurations of inactive and activated DntR have implications for the sliding dimer mechanism of LysR transcription factors. Scientific Reports. 6: 19988. PMID 26817994 DOI: 10.1038/srep19988  1
2015 von Ballmoos C, Biner O, Nilsson T, Brzezinski P. Mimicking respiratory phosphorylation using purified enzymes. Biochimica Et Biophysica Acta. PMID 26707617 DOI: 10.1016/j.bbabio.2015.12.007  0.68
2015 Vilhjálmsdóttir J, Johansson AL, Brzezinski P. Structural Changes and Proton Transfer in Cytochrome c Oxidase. Scientific Reports. 5: 12047. PMID 26310633 DOI: 10.1038/srep12047  1
2015 von Ballmoos C, Gonska N, Lachmann P, Gennis RB, Ädelroth P, Brzezinski P. Mutation of a single residue in the ba3 oxidase specifically impairs protonation of the pump site. Proceedings of the National Academy of Sciences of the United States of America. 112: 3397-402. PMID 25733886 DOI: 10.1073/pnas.1422434112  1
2014 Kim I, Chakrabarty S, Brzezinski P, Warshel A. Modeling gating charge and voltage changes in response to charge separation in membrane proteins. Proceedings of the National Academy of Sciences of the United States of America. 111: 11353-8. PMID 25049404 DOI: 10.1073/pnas.1411573111  1
2014 Svahn E, Faxén K, Gennis RB, Brzezinski P. Proton pumping by an inactive structural variant of cytochrome c oxidase. Journal of Inorganic Biochemistry. 140: 6-11. PMID 25042731 DOI: 10.1016/j.jinorgbio.2014.06.016  1
2014 Nordlund G, Brzezinski P, von Ballmoos C. SNARE-fusion mediated insertion of membrane proteins into native and artificial membranes. Nature Communications. 5: 4303. PMID 24985889 DOI: 10.1038/ncomms5303  0.68
2014 Näsvik Öjemyr L, Maréchal A, Vestin H, Meunier B, Rich PR, Brzezinski P. Reaction of wild-type and Glu243Asp variant yeast cytochrome c oxidase with O2 Biochimica Et Biophysica Acta - Bioenergetics. 1837: 1012-1018. PMID 24685432 DOI: 10.1016/j.bbabio.2014.03.012  1
2014 Nordlund G, Brzezinski P, Von Ballmoos C. SNARE-fusion mediated insertion of membrane proteins into native and artificial membranes Nature Communications. 5. DOI: 10.1038/ncomms5303  1
2013 Smirnova I, Chang HY, von Ballmoos C, Ädelroth P, Gennis RB, Brzezinski P. Single mutations that redirect internal proton transfer in the ba3 oxidase from Thermus thermophilus. Biochemistry. 52: 7022-30. PMID 24004023 DOI: 10.1021/bi4008726  1
2013 Johansson AL, Högbom M, Carlsson J, Gennis RB, Brzezinski P. Role of aspartate 132 at the orifice of a proton pathway in cytochrome c oxidase. Proceedings of the National Academy of Sciences of the United States of America. 110: 8912-7. PMID 23674679 DOI: 10.1073/pnas.1303954110  1
2013 Brzezinski P, Öjemyr LN, Ädelroth P. Intermediates generated during the reaction of reduced Rhodobacter sphaeroides cytochrome c oxidase with dioxygen Biochimica Et Biophysica Acta - Bioenergetics. 1827: 843-847. PMID 23643727 DOI: 10.1016/j.bbabio.2013.04.007  1
2013 Piper-Feldkamp AR, Wegner M, Brzezinski P, Reed SM. Mixtures of supported and hybrid lipid membranes on heterogeneously modified silica nanoparticles. The Journal of Physical Chemistry. B. 117: 2113-22. PMID 23387352 DOI: 10.1021/jp308305y  1
2013 Johansson AL, Carlsson J, Högbom M, Hosler JP, Gennis RB, Brzezinski P. Proton uptake and pKa changes in the uncoupled Asn139Cys variant of cytochrome c oxidase. Biochemistry. 52: 827-36. PMID 23305515 DOI: 10.1021/bi301597a  1
2012 von Ballmoos C, Lachmann P, Gennis RB, Ädelroth P, Brzezinski P. Timing of electron and proton transfer in the ba(3) cytochrome c oxidase from Thermus thermophilus. Biochemistry. 51: 4507-17. PMID 22624600 DOI: 10.1021/bi300132t  1
2012 Collins R, Johansson AL, Karlberg T, Markova N, van den Berg S, Olesen K, Hammarström M, Flores A, Schüler H, Schiavone LH, Brzezinski P, Arnér ES, Högbom M. Biochemical discrimination between selenium and sulfur 1: a single residue provides selenium specificity to human selenocysteine lyase. Plos One. 7: e30581. PMID 22295093 DOI: 10.1371/journal.pone.0030581  1
2012 Johansson AL, Collins R, Arnér ES, Brzezinski P, Högbom M. Biochemical discrimination between selenium and sulfur 2: mechanistic investigation of the selenium specificity of human selenocysteine lyase. Plos One. 7: e30528. PMID 22291978 DOI: 10.1371/journal.pone.0030528  0.52
2012 Öjemyr LN, Von Ballmoos C, Faxén K, Svahn E, Brzezinski P. The membrane modulates internal proton transfer in cytochrome c oxidase Biochemistry. 51: 1092-1100. PMID 22257086 DOI: 10.1021/bi201795c  1
2012 Näsvik Öjemyr L, von Ballmoos C, Gennis RB, Sligar SG, Brzezinski P. Reconstitution of respiratory oxidases in membrane nanodiscs for investigation of proton-coupled electron transfer. Febs Letters. 586: 640-5. PMID 22209982 DOI: 10.1016/j.febslet.2011.12.023  1
2012 von Ballmoos C, Adelroth P, Gennis RB, Brzezinski P. Proton transfer in ba(3) cytochrome c oxidase from Thermus thermophilus. Biochimica Et Biophysica Acta. 1817: 650-7. PMID 22172736 DOI: 10.1016/j.bbabio.2011.11.015  1
2012 Johansson AL, Collins R, Arnér ESJ, Brzezinski P, Högbom M. Biochemical discrimination between selenium and sulfur 2: Mechanistic investigation of the selenium specificity of human selenocysteine lyase Plos One. 7. DOI: 10.1371/journal.pone.0030528  1
2012 Lönneborg R, Varga E, Brzezinski P. Directed evolution of the transcriptional regulator DntR: Isolation of mutants with improved DNT-response Plos One. 7. DOI: 10.1371/journal.pone.0029994  1
2011 Lönneborg R, Brzezinski P. Factors that influence the response of the LysR type transcriptional regulators to aromatic compounds. Bmc Biochemistry. 12: 49. PMID 21884597 DOI: 10.1186/1471-2091-12-49  1
2011 Devesse L, Smirnova I, Lönneborg R, Kapp U, Brzezinski P, Leonard GA, Dian C. Crystal structures of DntR inducer binding domains in complex with salicylate offer insights into the activation of LysR-type transcriptional regulators. Molecular Microbiology. 81: 354-67. PMID 21692874 DOI: 10.1111/j.1365-2958.2011.07673.x  1
2011 von Ballmoos C, Gennis RB, Ädelroth P, Brzezinski P. Kinetic design of the respiratory oxidases. Proceedings of the National Academy of Sciences of the United States of America. 108: 11057-62. PMID 21690359 DOI: 10.1073/pnas.1104103108  1
2011 Johansson AL, Chakrabarty S, Berthold CL, Högbom M, Warshel A, Brzezinski P. Proton-transport mechanisms in cytochrome c oxidase revealed by studies of kinetic isotope effects. Biochimica Et Biophysica Acta. 1807: 1083-94. PMID 21463601 DOI: 10.1016/j.bbabio.2011.03.012  1
2011 Xia Y, Lundbäck AK, Sahaf N, Nordlund G, Brzezinski P, Eshaghi S. Co2+ selectivity of Thermotoga maritima CorA and its inability to regulate Mg2+ homeostasis present a new class of CorA proteins Journal of Biological Chemistry. 286: 16525-16532. PMID 21454699 DOI: 10.1074/jbc.M111.222166  1
2011 Namslauer I, Dietz MS, Brzezinski P. Functional effects of mutations in cytochrome c oxidase related to prostate cancer. Biochimica Et Biophysica Acta. 1807: 1336-41. PMID 21334999 DOI: 10.1016/j.bbabio.2011.02.005  1
2011 Chakrabarty S, Namslauer I, Brzezinski P, Warshel A. Exploration of the cytochrome c oxidase pathway puzzle and examination of the origin of elusive mutational effects. Biochimica Et Biophysica Acta. 1807: 413-26. PMID 21232525 DOI: 10.1016/j.bbabio.2011.01.004  1
2010 Lee HJ, Svahn E, Swanson JM, Lepp H, Voth GA, Brzezinski P, Gennis RB. Intricate role of water in proton transport through cytochrome c oxidase. Journal of the American Chemical Society. 132: 16225-39. PMID 20964330 DOI: 10.1021/ja107244g  1
2010 Ojemyr LN, Lee HJ, Gennis RB, Brzezinski P. Functional interactions between membrane-bound transporters and membranes. Proceedings of the National Academy of Sciences of the United States of America. 107: 15763-7. PMID 20798065 DOI: 10.1073/pnas.1006109107  1
2010 Smirnova I, Reimann J, von Ballmoos C, Chang HY, Gennis RB, Fee JA, Brzezinski P, Adelroth P. Functional role of Thr-312 and Thr-315 in the proton-transfer pathway in ba3 Cytochrome c oxidase from Thermus thermophilus. Biochemistry. 49: 7033-9. PMID 20677778 DOI: 10.1021/bi100749p  1
2010 Brzezinski P, Johansson AL. Variable proton-pumping stoichiometry in structural variants of cytochrome c oxidase Biochimica Et Biophysica Acta - Bioenergetics. 1797: 710-723. PMID 20184858 DOI: 10.1016/j.bbabio.2010.02.020  1
2010 Sandén T, Salomonsson L, Brzezinski P, Widengren J. Surface-coupled proton exchange of a membrane-bound proton acceptor Proceedings of the National Academy of Sciences of the United States of America. 107: 4129-4134. PMID 20160117 DOI: 10.1073/pnas.0908671107  1
2010 Namslauer I, Lee HJ, Gennis RB, Brzezinski P. A pathogenic mutation in cytochrome c oxidase results in impaired proton pumping while retaining O(2)-reduction activity. Biochimica Et Biophysica Acta. 1797: 550-6. PMID 20117076 DOI: 10.1016/j.bbabio.2010.01.027  1
2009 Nordlund G, Sing Ng JB, Bergström L, Brzezinski P. A membrane-reconstituted multisubunit functional proton pump on mesoporous silica particles Acs Nano. 3: 2639-2646. PMID 19653679 DOI: 10.1021/nn9005413  1
2009 Lee HJ, Ojemyr L, Vakkasoglu A, Brzezinski P, Gennis RB. Properties of Arg481 mutants of the aa3-type cytochrome c oxidase from Rhodobacter sphaeroides suggest that neither R481 nor the nearby D-propionate of heme a3 is likely to be the proton loading site of the proton pump. Biochemistry. 48: 7123-31. PMID 19575527 DOI: 10.1021/bi901015d  1
2009 Lepp H, Brzezinski P. Internal charge transfer in cytochrome c oxidase at a limited proton supply: Proton pumping ceases at high pH Biochimica Et Biophysica Acta - General Subjects. 1790: 552-557. PMID 19344748 DOI: 10.1016/j.bbagen.2009.03.023  1
2009 Nordlund G, Lönneborg R, Brzezinski P. Formation of supported lipid bilayers on silica particles studied using flow cytometry Langmuir. 25: 4601-4606. PMID 19265407 DOI: 10.1021/la8036296  1
2009 Namslauer I, Brzezinski P. A mitochondrial DNA mutation linked to colon cancer results in proton leaks in cytochrome c oxidase Proceedings of the National Academy of Sciences of the United States of America. 106: 3402-3407. PMID 19218458 DOI: 10.1073/pnas.0811450106  1
2009 Öjemyr L, Sandén T, Widengren J, Brzezinski P. Lateral proton transfer between the membrane and a membrane protein Biochemistry. 48: 2173-2179. PMID 19166299 DOI: 10.1021/bi8022152  1
2008 Brzezinski P, Reimann J, Ädelroth P. Molecular architecture of the proton diode of cytochrome c oxidase Biochemical Society Transactions. 36: 1169-1174. PMID 19021518 DOI: 10.1042/BST0361169  1
2008 Brzezinski P, Gennis RB. Cytochrome c oxidase: exciting progress and remaining mysteries. Journal of Bioenergetics and Biomembranes. 40: 521-31. PMID 18975062 DOI: 10.1007/s10863-008-9181-7  1
2008 Smirnova IA, Zaslavsky D, Fee JA, Gennis RB, Brzezinski P. Electron and proton transfer in the ba(3) oxidase from Thermus thermophilus. Journal of Bioenergetics and Biomembranes. 40: 281-7. PMID 18752061 DOI: 10.1007/s10863-008-9157-7  1
2008 Lepp H, Salomonsson L, Zhu JP, Gennis RB, Brzezinski P. Impaired proton pumping in cytochrome c oxidase upon structural alteration of the D pathway. Biochimica Et Biophysica Acta. 1777: 897-903. PMID 18457654 DOI: 10.1016/j.bbabio.2008.04.013  1
2008 Lepp H, Svahn E, Faxén K, Brzezinski P. Charge transfer in the K proton pathway linked to electron transfer to the catalytic site in cytochrome c oxidase Biochemistry. 47: 4929-4935. PMID 18393448 DOI: 10.1021/bi7024707  1
2008 Salomonsson L, Brändén G, Brzezinski P. Deuterium isotope effect of proton pumping in cytochrome c oxidase Biochimica Et Biophysica Acta - Bioenergetics. 1777: 343-350. PMID 18371493 DOI: 10.1016/j.bbabio.2007.09.009  1
2008 Busenlehner LS, Brändén G, Namslauer I, Brzezinski P, Armstrong RN. Structural elements involved in proton translocation by cytochrome c oxidase as revealed by backbone amide hydrogen-deuterium exchange of the E286H mutant. Biochemistry. 47: 73-83. PMID 18052347 DOI: 10.1021/bi701643a  1
2007 Lönneborg R, Smirnova I, Dian C, Leonard GA, Brzezinski P. In vivo and in vitro investigation of transcriptional regulation by DntR. Journal of Molecular Biology. 372: 571-82. PMID 17681542 DOI: 10.1016/j.jmb.2007.06.076  1
2007 Faxén K, Brzezinski P. The inside pH determines rates of electron and proton transfer in vesicle-reconstituted cytochrome c oxidase Biochimica Et Biophysica Acta - Bioenergetics. 1767: 381-386. PMID 17466260 DOI: 10.1016/j.bbabio.2007.02.023  1
2007 Namslauer A, Lepp H, Brändén M, Jasaitis A, Verkhovsky MI, Brzezinski P. Plasticity of proton pathway structure and water coordination in cytochrome c oxidase Journal of Biological Chemistry. 282: 15148-15158. PMID 17363369 DOI: 10.1074/jbc.M700348200  1
2006 Brändén M, Sandén T, Brzezinski P, Widengren J. Localized proton microcircuits at the biological membrane-water interface Proceedings of the National Academy of Sciences of the United States of America. 103: 19766-19770. PMID 17172452 DOI: 10.1073/pnas.0605909103  1
2006 Han D, Namslauer A, Pawate A, Morgan JE, Nagy S, Vakkasoglu AS, Brzezinski P, Gennis RB. Replacing Asn207 by aspartate at the neck of the D channel in the aa3-type cytochrome c oxidase from Rhodobacter sphaeroides results in decoupling the proton pump. Biochemistry. 45: 14064-74. PMID 17115701 DOI: 10.1021/bi061465q  1
2006 Busenlehner LS, Salomonsson L, Brzezinski P, Armstrong RN. Mapping protein dynamics in catalytic intermediates of the redox-driven proton pump cytochrome c oxidase. Proceedings of the National Academy of Sciences of the United States of America. 103: 15398-403. PMID 17023543 DOI: 10.1073/pnas.0601451103  1
2006 Brzezinski P, Ädelroth P. Design principles of proton-pumping haem-copper oxidases Current Opinion in Structural Biology. 16: 465-472. PMID 16842995 DOI: 10.1016/j.sbi.2006.06.012  1
2006 Brändén G, Gennis RB, Brzezinski P. Transmembrane proton translocation by cytochrome c oxidase. Biochimica Et Biophysica Acta. 1757: 1052-63. PMID 16824482 DOI: 10.1016/j.bbabio.2006.05.020  1
2006 Faxén K, Salomonsson L, Ädelroth P, Brzezinski P. Inhibition of proton pumping by zinc ions during specific reaction steps in cytochrome c oxidase Biochimica Et Biophysica Acta - Bioenergetics. 1757: 388-394. PMID 16806055 DOI: 10.1016/j.bbabio.2006.05.010  1
2006 Björklund J, Biverståhl H, Gräslund A, Mäler L, Brzezinski P. Real-time transmembrane translocation of penetratin driven by light-generated proton pumping. Biophysical Journal. 91: L29-31. PMID 16782795 DOI: 10.1529/biophysj.106.083881  1
2006 Brändén G, Pawate AS, Gennis RB, Brzezinski P. Controlled uncoupling and recoupling of proton pumping in cytochrome c oxidase. Proceedings of the National Academy of Sciences of the United States of America. 103: 317-22. PMID 16407159 DOI: 10.1073/pnas.0507734103  1
2005 Salomonsson L, Faxén K, Ädelroth P, Brzezinski P. The timing of proton migration in membrane-reconstituted cytochrome c oxidase Proceedings of the National Academy of Sciences of the United States of America. 102: 17624-17629. PMID 16306266 DOI: 10.1073/pnas.0505431102  1
2005 Brzezinski P. Spotlight on... Peter Brzezinski Febs Letters. 579: 5113. PMID 16162345 DOI: 10.1016/j.febslet.2005.08.045  1
2005 Faxén K, Gilderson G, Ädelroth P, Brzezinski P. A mechanistic principle for proton pumping by cytochrome c oxidase Nature. 437: 286-289. PMID 16148937 DOI: 10.1038/nature03921  1
2005 Brändén G, Brändén M, Schmidt B, Mills DA, Ferguson-Miller S, Brzezinski P. The protonation state of a heme propionate controls electron transfer in cytochrome c oxidase. Biochemistry. 44: 10466-74. PMID 16060655 DOI: 10.1021/bi0502745  1
2004 Salomonsson L, Lee A, Gennis RB, Brzezinski P. A single-amino-acid lid renders a gas-tight compartment within a membrane-bound transporter. Proceedings of the National Academy of Sciences of the United States of America. 101: 11617-21. PMID 15289603 DOI: 10.1073/pnas.0402242101  1
2004 Brzezinski P. Redox-driven membrane-bound proton pumps. Trends in Biochemical Sciences. 29: 380-7. PMID 15236746 DOI: 10.1016/j.tibs.2004.05.008  1
2004 Smirnova IA, Dian C, Leonard GA, McSweeney S, Birse D, Brzezinski P. Development of a bacterial biosensor for nitrotoluenes: the crystal structure of the transcriptional regulator DntR. Journal of Molecular Biology. 340: 405-18. PMID 15210343 DOI: 10.1016/j.jmb.2004.04.071  1
2004 Namslauer A, Brzezinski P. Structural elements involved in electron-coupled proton transfer in cytochrome c oxidase. Febs Letters. 567: 103-10. PMID 15165901 DOI: 10.1016/j.febslet.2004.04.027  1
2004 Adelroth P, Brzezinski P. Surface-mediated proton-transfer reactions in membrane-bound proteins. Biochimica Et Biophysica Acta. 1655: 102-15. PMID 15100022 DOI: 10.1016/j.bbabio.2003.10.018  1
2004 Brzezinski P, Ehrenberg A, Tommos C. Biochimica et Biophysica Acta - Bioenergetics: Introduction Biochimica Et Biophysica Acta - Bioenergetics. 1655: 1. DOI: 10.1016/j.bbabio.2004.02.004  1
2003 Namslauer A, Pawate AS, Gennis RB, Brzezinski P. Redox-coupled proton translocation in biological systems: proton shuttling in cytochrome c oxidase. Proceedings of the National Academy of Sciences of the United States of America. 100: 15543-7. PMID 14676323 DOI: 10.1073/pnas.2432106100  1
2003 Brändén M, Namslauer A, Hansson O, Aasa R, Brzezinski P. Water-hydroxide exchange reactions at the catalytic site of heme-copper oxidases. Biochemistry. 42: 13178-84. PMID 14609328 DOI: 10.1021/bi0347407  1
2003 Brzezinski P, Larsson G. Redox-driven proton pumping by heme-copper oxidases. Biochimica Et Biophysica Acta. 1605: 1-13. PMID 12907296 DOI: 10.1016/S0005-2728(03)00079-3  1
2003 Gilderson G, Salomonsson L, Aagaard A, Gray J, Brzezinski P, Hosler J. Subunit III of cytochrome c oxidase of Rhodobacter sphaeroides is required to maintain rapid proton uptake through the D pathway at physiologic pH. Biochemistry. 42: 7400-9. PMID 12809495 DOI: 10.1021/bi0341298  1
2003 Namslauer A, Aagaard A, Katsonouri A, Brzezinski P. Intramolecular proton-transfer reactions in a membrane-bound proton pump: the effect of pH on the peroxy to ferryl transition in cytochrome c oxidase. Biochemistry. 42: 1488-98. PMID 12578361 DOI: 10.1021/bi026524o  1
2003 Brzezinski P, Von Heijne G, Rydström J. Membrane proteins: Structure, function and assembly Febs Letters. 555: 1. DOI: 10.1016/S0014-5793(03)01147-5  1
2002 Pawate AS, Morgan J, Namslauer A, Mills D, Brzezinski P, Ferguson-Miller S, Gennis RB. A mutation in subunit I of cytochrome oxidase from Rhodobacter sphaeroides results in an increase in steady-state activity but completely eliminates proton pumping. Biochemistry. 41: 13417-23. PMID 12416987 DOI: 10.1021/bi026582+  1
2002 Aagaard A, Namslauer A, Brzezinski P. Inhibition of proton transfer in cytochrome c oxidase by zinc ions: delayed proton uptake during oxygen reduction. Biochimica Et Biophysica Acta. 1555: 133-9. PMID 12206905 DOI: 10.1016/S0005-2728(02)00268-2  1
2002 Brändén M, Tomson F, Gennis RB, Brzezinski P. The entry point of the K-proton-transfer pathway in cytochrome c oxidase. Biochemistry. 41: 10794-8. PMID 12196018 DOI: 10.1021/bi026093+  1
2002 Namslauer A, Brändén M, Brzezinski P. The rate of internal heme-heme electron transfer in cytochrome C oxidase. Biochemistry. 41: 10369-74. PMID 12173922 DOI: 10.1021/bi025976y  1
2002 Svensson-Ek M, Abramson J, Larsson G, Törnroth S, Brzezinski P, Iwata S. The X-ray crystal structures of wild-type and EQ(I-286) mutant cytochrome c oxidases from Rhodobacter sphaeroides. Journal of Molecular Biology. 321: 329-39. PMID 12144789 DOI: 10.1016/S0022-2836(02)00619-8  1
2002 Gilderson G, Aagaard A, Brzezinski P. Relocation of an internal proton donor in cytochrome c oxidase results in an altered pK(a) and a non-integer pumping stoichiometry. Biophysical Chemistry. 98: 105-14. PMID 12128193 DOI: 10.1016/S0301-4622(02)00088-1  1
2002 Silkstone G, Stanway G, Brzezinski P, Wilson MT. Production and characterisation of Met80X mutants of yeast iso-1-cytochrome c: spectral, photochemical and binding studies on the ferrous derivatives. Biophysical Chemistry. 98: 65-77. PMID 12128190 DOI: 10.1016/S0301-4622(02)00085-6  1
2002 Sigurdson H, Brändén M, Namslauer A, Brzezinski P. Ligand binding reveals protonation events at the active site of cytochrome c oxidase; is the K-pathway used for the transfer of H(+) or OH(-)? Journal of Inorganic Biochemistry. 88: 335-42. PMID 11897348 DOI: 10.1016/S0162-0134(01)00348-8  1
2002 Heitbrink D, Sigurdson H, Bolwien C, Brzezinski P, Heberle J. Transient binding of CO to Cu(B) in cytochrome c oxidase is dynamically linked to structural changes around a carboxyl group: a time-resolved step-scan Fourier transform infrared investigation. Biophysical Journal. 82: 1-10. PMID 11751290 DOI: 10.1016/S0006-3495(02)75368-X  1
2001 Sigurdson H, Namslauer A, Pereira MM, Teixeira M, Brzezinski P. Ligand binding and the catalytic reaction of cytochrome caa(3) from the thermophilic bacterium Rhodothermus marinus. Biochemistry. 40: 10578-85. PMID 11524000 DOI: 10.1021/bi010344h  1
2001 Bellelli A, Brunori M, Brzezinski P, Wilson MT. Photochemically induced electron transfer. Methods (San Diego, Calif.). 24: 139-52. PMID 11384189 DOI: 10.1006/meth.2001.1175  1
2001 Aagaard A, Brzezinski P. Zinc ions inhibit oxidation of cytochrome c oxidase by oxygen. Febs Letters. 494: 157-60. PMID 11311232 DOI: 10.1016/S0014-5793(01)02299-2  1
2001 Brändén M, Sigurdson H, Namslauer A, Gennis RB, Adelroth P, Brzezinski P. On the role of the K-proton transfer pathway in cytochrome c oxidase. Proceedings of the National Academy of Sciences of the United States of America. 98: 5013-8. PMID 11296255 DOI: 10.1073/pnas.081088398  1
2001 Gilderson G, Aagaard A, Gomes CM, Adelroth P, Teixeira M, Brzezinski P. Kinetics of electron and proton transfer during O(2) reduction in cytochrome aa(3) from A. ambivalens: an enzyme lacking Glu(I-286). Biochimica Et Biophysica Acta. 1503: 261-70. PMID 11115638 DOI: 10.1016/S0005-2728(00)00195-X  1
2000 Aagaard A, Gilderson G, Mills DA, Ferguson-Miller S, Brzezinski P. Redesign of the proton-pumping machinery of cytochrome c oxidase: proton pumping does not require Glu(I-286). Biochemistry. 39: 15847-50. PMID 11123910 DOI: 10.1021/bi0012641  1
2000 Karpefors M, Adelroth P, Namslauer A, Zhen Y, Brzezinski P. Formation of the "peroxy" intermediate in cytochrome c oxidase is associated with internal proton/hydrogen transfer. Biochemistry. 39: 14664-9. PMID 11087423 DOI: 10.1021/bi0013748  1
2000 Adelroth P, Karpefors M, Gilderson G, Tomson FL, Gennis RB, Brzezinski P. Proton transfer from glutamate 286 determines the transition rates between oxygen intermediates in cytochrome c oxidase. Biochimica Et Biophysica Acta. 1459: 533-9. PMID 11004473 DOI: 10.1016/S0005-2728(00)00194-8  1
2000 Sjögren T, Svensson-Ek M, Hajdu J, Brzezinski P. Proton-coupled structural changes upon binding of carbon monoxide to cytochrome cd1: a combined flash photolysis and X-ray crystallography study. Biochemistry. 39: 10967-74. PMID 10998233 DOI: 10.1021/bi000179q  1
2000 Karpefors M, Adelroth P, Brzezinski P. Localized control of proton transfer through the D-pathway in cytochrome c oxidase: application of the proton-inventory technique. Biochemistry. 39: 6850-6. PMID 10841765 DOI: 10.1021/bi992719t  1
2000 Karpefors M, Adelroth P, Brzezinski P. The onset of the deuterium isotope effect in cytochrome c oxidase. Biochemistry. 39: 5045-50. PMID 10819969 DOI: 10.1021/bi9925221  1
2000 Brzezinski P. Proton-transfer reactions in bioenergetics. Biochimica Et Biophysica Acta. 1458: 1-5. PMID 10812021 DOI: 10.1016/S0005-2728(00)00056-6  1
1999 Zaslavsky D, Smirnova IA, Brzezinski P, Shinzawa-Itoh K, Yoshikawa S, Gennis RB. Examination of the reaction of fully reduced cytochrome oxidase with hydrogen peroxide by flow-flash spectroscopy. Biochemistry. 38: 16016-23. PMID 10625470 DOI: 10.1021/bi9916675  1
1999 Ma J, Tsatsos PH, Zaslavsky D, Barquera B, Thomas JW, Katsonouri A, Puustinen A, Wikström M, Brzezinski P, Alben JO, Gennis RB. Glutamate-89 in subunit II of cytochrome bo3 from Escherichia coli is required for the function of the heme-copper oxidase. Biochemistry. 38: 15150-6. PMID 10563797 DOI: 10.1021/bi991764y  1
1999 Aagaard A, Gilderson G, Gomes CM, Teixeira M, Brzezinski P. Dynamics of the binuclear center of the quinol oxidase from Acidianus ambivalens. Biochemistry. 38: 10032-41. PMID 10433710 DOI: 10.1021/bi990473m  1
1999 Wilson EK, Bellelli A, Liberti S, Arese M, Grasso S, Cutruzzolà F, Brunori M, Brzezinski P. Internal electron transfer and structural dynamics of cd1 nitrite reductase revealed by laser CO photodissociation. Biochemistry. 38: 7556-64. PMID 10360953 DOI: 10.1021/bi990179u  1
1999 Smirnova IA, Adelroth P, Gennis RB, Brzezinski P. Aspartate-132 in cytochrome c oxidase from Rhodobacter sphaeroides is involved in a two-step proton transfer during oxo-ferryl formation. Biochemistry. 38: 6826-33. PMID 10346904 DOI: 10.1021/bi982865j  1
1999 Zaslavsky D, Smirnova IA, Adelroth P, Brzezinski P, Gennis RB. Observation of a novel transient ferryl complex with reduced CuB in cytochrome c oxidase. Biochemistry. 38: 2307-11. PMID 10029523 DOI: 10.1021/bi9822832  1
1999 Karpefors M, Ädelroth P, Aagaard A, Smirnova IA, Brzezinski P. The Deuterium Isotope Effect as a tool to investigate enzyme catalysis: Proton-transfer control mechanisms in cytochrome c oxidase Israel Journal of Chemistry. 39: 427-437.  1
1998 Karpefors M, Adelroth P, Zhen Y, Ferguson-Miller S, Brzezinski P. Proton uptake controls electron transfer in cytochrome c oxidase. Proceedings of the National Academy of Sciences of the United States of America. 95: 13606-11. PMID 9811847 DOI: 10.1073/pnas.95.23.13606  1
1998 Brzezinski P, Adelroth P. Proton-controlled electron transfer in cytochrome c oxidase: functional role of the pathways through Glu 286 and Lys 362. Acta Physiologica Scandinavica. Supplementum. 643: 7-16. PMID 9789542  1
1998 Adelroth P, Ek M, Brzezinski P. Factors determining electron-transfer rates in cytochrome c oxidase: investigation of the oxygen reaction in the R. sphaeroides enzyme. Biochimica Et Biophysica Acta. 1367: 107-17. PMID 9784618 DOI: 10.1016/S0005-2728(98)00142-X  1
1998 Höök F, Rodahl M, Kasemo B, Brzezinski P. Structural changes in hemoglobin during adsorption to solid surfaces: Effects of pH, ionic strength, and ligand binding Proceedings of the National Academy of Sciences of the United States of America. 95: 12271-12276. PMID 9770476 DOI: 10.1073/pnas.95.21.12271  1
1998 Brzezinski P, Messinger A, Blatt Y, Gopher A, Kleinfeld D. Charge displacements in interfacial layers containing reaction centers. The Journal of Membrane Biology. 165: 213-25. PMID 9767675 DOI: 10.1007/s002329900435  1
1998 Karpefors M, Adelroth P, Aagaard A, Sigurdson H, Svensson Ek M, Brzezinski P. Electron-proton interactions in terminal oxidases. Biochimica Et Biophysica Acta. 1365: 159-69. PMID 9693734 DOI: 10.1016/S0005-2728(98)00058-9  1
1998 Marantz Y, Nachliel E, Aagaard A, Brzezinski P, Gutman M. The proton collecting function of the inner surface of cytochrome c oxidase from Rhodobacter sphaeroides Proceedings of the National Academy of Sciences of the United States of America. 95: 8590-8595. PMID 9671722 DOI: 10.1073/pnas.95.15.8590  1
1998 Karpefors M, Wilson MT, Brzezinski P. Photoinduced electron transfer from carboxymethylated cytochrome c to plastocyanin Biochimica Et Biophysica Acta - Bioenergetics. 1364: 385-389. PMID 9630728 DOI: 10.1016/S0005-2728(98)00063-2  1
1998 Brzezinski P, Adelroth P. Pathways of proton transfer in cytochrome c oxidase. Journal of Bioenergetics and Biomembranes. 30: 99-107. PMID 9623811 DOI: 10.1023/A:1020567729941  1
1998 Adelroth P, Gennis RB, Brzezinski P. Role of the pathway through K(I-362) in proton transfer in cytochrome c oxidase from R. sphaeroides. Biochemistry. 37: 2470-6. PMID 9485395 DOI: 10.1021/bi971813b  1
1998 Smirnova IA, Blomberg A, Andréasson LE, Brzezinski P. Localization of light-induced structural changes in bacterial photosynthetic reaction centers Photosynthesis Research. 56: 45-55. DOI: 10.1023/A:1005934411312  1
1998 Höök F, Rodahl M, Brzezinski P, Kasemo B. Measurements using the quartz crystal microbalance technique of ferritin monolayers on methyl-thiolated gold: Dependence of energy dissipation and saturation coverage on salt concentration Journal of Colloid and Interface Science. 208: 63-67. DOI: 10.1006/jcis.1998.5774  1
1998 Höök F, Rodahl M, Brzezinski P, Kasemo B. Energy dissipation kinetics for protein and antibody-antigen adsorption under shear oscillation on a quartz crystal microbalance Langmuir. 14: 729-734.  1
1997 Rodahl M, Höök F, Fredriksson C, Keller CA, Krozer A, Brzezinski P, Voinova M, Kasemo B. Simultaneous frequency and dissipation factor QCM measurements of biomolecular adsorption and cell adhesion Faraday Discussions. 107: 229-246. PMID 9569776  1
1997 Adelroth P, Ek MS, Mitchell DM, Gennis RB, Brzezinski P. Glutamate 286 in cytochrome aa3 from Rhodobacter sphaeroides is involved in proton uptake during the reaction of the fully-reduced enzyme with dioxygen. Biochemistry. 36: 13824-9. PMID 9374859 DOI: 10.1021/bi9629079  1
1997 Brzezinski P, Paddock ML, Okamura MY, Feher G. Light-induced electrogenic events associated with proton uptake upon forming QB- in bacterial wild-type and mutant reaction centers. Biochimica Et Biophysica Acta. 1321: 149-56. PMID 9332502 DOI: 10.1016/S0005-2728(97)00052-2  1
1997 Adelroth P, Mitchell DM, Gennis RB, Brzezinski P. Factors determining electron-transfer rates in cytochrome c oxidase: studies of the FQ(I-391) mutant of the Rhodobacter sphaeroides enzyme. Biochemistry. 36: 11787-96. PMID 9305969 DOI: 10.1021/bi962824s  1
1997 Brzezinski P, Wilson MT. Photochemical electron injection into redox-active proteins Proceedings of the National Academy of Sciences of the United States of America. 94: 6176-6179. PMID 9177190 DOI: 10.1073/pnas.94.12.6176  1
1997 Svensson Ek M, Brzezinski P. Oxidation of ubiquinol by cytochrome bo3 from Escherichia coli: Kinetics of electron and proton transfer Biochemistry. 36: 5425-5431. PMID 9154924 DOI: 10.1021/bi962478e  1
1996 Hirota S, Svensson-Ek M, Adelroth P, Sone N, Nilsson T, Malmström BG, Brzezinski P. A flash-photolysis study of the reactions of a caa3-type cytochrome oxidase with dioxygen and carbon monoxide. Journal of Bioenergetics and Biomembranes. 28: 495-501. PMID 8953381  1
1996 Bellelli A, Brzezinski P, Arese M, Cutruzzolà F, Silvestrini MC, Brunori M. Electron transfer in zinc-reconstituted nitrite reductase from Pseudomonas aeruginosa Biochemical Journal. 319: 407-410. PMID 8912674  1
1996 Adelroth P, Sigurdson H, Hallén S, Brzezinski P. Kinetic coupling between electron and proton transfer in cytochrome c oxidase: simultaneous measurements of conductance and absorbance changes. Proceedings of the National Academy of Sciences of the United States of America. 93: 12292-7. PMID 8901574 DOI: 10.1073/pnas.93.22.12292  1
1996 Svensson-Ek M, Thomas JW, Gennis RB, Nilsson T, Brzezinski P. Kinetics of electron and proton transfer during the reaction of wild type and helix VI mutants of cytochrome bo3 with oxygen. Biochemistry. 35: 13673-80. PMID 8885847 DOI: 10.1021/bi961466q  1
1996 Mitchell DM, Fetter JR, Mills DA, Adelroth P, Pressler MA, Kim Y, Aasa R, Brzezinski P, Malmström BG, Alben JO, Båbcock GT, Ferguson-Miller S, Gennis RB. Site-directed mutagenesis of residues lining a putative proton transfer pathway in cytochrome c oxidase from Rhodobacter sphaeroides. Biochemistry. 35: 13089-93. PMID 8855945 DOI: 10.1021/bi961416l  1
1996 Brzezinski P. Internal electron-transfer reactions in cytochrome c oxidase Biochemistry. 35: 5611-5615. PMID 8639518 DOI: 10.1021/bi960260m  1
1996 Mitchell DM, Adelroth P, Hosler JP, Fetter JR, Brzezinski P, Pressler MA, Aasa R, Malmström BG, Alben JO, Babcock GT, Gennis RB, Ferguson-Miller S. A ligand-exchange mechanism of proton pumping involving tyrosine-422 of subunit I of cytochrome oxidase is ruled out. Biochemistry. 35: 824-8. PMID 8547262 DOI: 10.1021/bi951897t  1
1995 Adelroth P, Brzezinski P, Malmström BG. Internal electron transfer in cytochrome c oxidase from Rhodobacter sphaeroides. Biochemistry. 34: 2844-9. PMID 7893697  1
1995 Brzezinski P, Andreasson LE. Trypsin treatment of reaction centers from Rhodobacter sphaeroides in the dark and under illumination: Protein structural changes follow charge separation Biochemistry. 34: 7498-7506. PMID 7779794 DOI: 10.1021/bi00022a025  1
1995 Brzezinski P, Sundahl M, Adelroth P, Wilson MT, el-Agez B, Wittung P, Malmström BG. Triplet-state quenching in complexes between Zn-cytochrome c and cytochrome oxidase or its CuA domain. Biophysical Chemistry. 54: 191-7. PMID 7756569 DOI: 10.1016/0301-4622(94)00128-7  1
1995 Mitchell DM, Aasa R, Adelroth P, Brzezinski P, Gennis RB, Malmström BG. EPR studies of wild-type and several mutants of cytochrome c oxidase from Rhodobacter sphaeroides: Glu286 is not a bridging ligand in the cytochrome a3-CuB center. Febs Letters. 374: 371-4. PMID 7589573 DOI: 10.1016/0014-5793(95)01149-9  1
1995 Rodahl M, Höök F, Krozer A, Brzezinski P, Kasemo B. Quartz crystal microbalance setup for frequency and Q-factor measurements in gaseous and liquid environments Review of Scientific Instruments. 66: 3924-3930. DOI: 10.1063/1.1145396  1
1995 Sigfridsson K, Hansson O, Brzezinski P. Electrogenic light reactions in photosystem I: Resolution of electron- transfer rates between the iron-sulfur centers Proceedings of the National Academy of Sciences of the United States of America. 92: 3458-3462.  1
1994 Hallén S, Brzezinski P, Malmström BG. Internal electron transfer in cytochrome c oxidase is coupled to the protonation of a group close to the bimetallic site. Biochemistry. 33: 1467-72. PMID 8312266  1
1994 Hook F, Brzezinski P. Light-induced voltage changes associated with electron and proton transfer in photosystem II core complexes reconstituted in phospholipid monolayers Biophysical Journal. 66: 2066-2072. PMID 8075340  1
1988 Thörnström PE, Brzezinski P, Fredriksson PO, Malmström BG. Cytochrome c oxidase as an electron-transport-driven proton pump: pH dependence of the reduction levels of the redox centers during turnover. Biochemistry. 27: 5441-7. PMID 2846037  1
1988 Brzezinski P, Malmström BG, Lorentzon P, Wallmark B. The catalytic mechanism of gastric H+/K+-ATPase: simulations of pre-steady-state and steady-state kinetic results. Biochimica Et Biophysica Acta. 942: 215-9. PMID 2840118 DOI: 10.1016/0005-2736(88)90022-3  1
1987 Fabian M, Thörnström PE, Brzezinski P, Malmström BG. Two-electron reduction is required for rapid internal electron transfer in resting, pulsed and oxygenated cytochrome c oxidase. Febs Letters. 213: 396-400. PMID 3030819 DOI: 10.1016/0014-5793(87)81529-6  1
1987 Brzezinski P, Malmström BG. The mechanism of electron gating in proton pumping cytochrome c oxidase: the effect of pH and temperature on internal electron transfer. Biochimica Et Biophysica Acta. 894: 29-38. PMID 2444256 DOI: 10.1016/0005-2728(87)90209-X  1
1985 Brzezinski P, Malmström BG. The reduction of cytochrome c oxidase by carbon monoxide. Febs Letters. 187: 111-4. PMID 2991001 DOI: 10.1016/0014-5793(85)81224-2  1
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