Loredano Pollegioni, PhD - Publications

Affiliations: 
University of Varese, Italy 
Area:
Biochemistry, protein ingineering

218 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Pollegioni L, Campanini B, Good JM, Motta Z, Murtas G, Buoli Comani V, Pavlidou DC, Mercier N, Mittaz-Crettol L, Sacchi S, Marchesani F. L-serine deficiency: on the properties of the Asn133Ser variant of human phosphoserine phosphatase. Scientific Reports. 14: 12463. PMID 38816452 DOI: 10.1038/s41598-024-63164-y  0.332
2023 Rabattoni V, Motta Z, Miceli M, Molla G, Fissore A, Adinolfi S, Pollegioni L, Sacchi S. On the regulation of human D-aspartate oxidase. Protein Science : a Publication of the Protein Society. 32: e4802. PMID 37805834 DOI: 10.1002/pro.4802  0.42
2023 Murtas G, Pollegioni L. D-Amino Acids and Cancer: Friends or Foes? International Journal of Molecular Sciences. 24. PMID 36834677 DOI: 10.3390/ijms24043274  0.383
2022 Murtas G, Pollegioni L, Molla G, Sacchi S. Biochemical Properties and Physiological Functions of pLG72: Twenty Years of Investigations. Biomolecules. 12. PMID 35740983 DOI: 10.3390/biom12060858  0.397
2022 Pollegioni L, Molla G. The conundrum in enzymatic reactions related to biosynthesis of d-amino acids in bacteria. The Febs Journal. PMID 35587531 DOI: 10.1111/febs.16475  0.465
2022 Boreggio M, Rosini E, Gambarotti C, Pollegioni L, Fasoli E. Unveiling the Bio-corona Fingerprinting of Potential Anticancer Carbon Nanotubes Coupled with D-Amino Acid Oxidase. Molecular Biotechnology. PMID 35467257 DOI: 10.1007/s12033-022-00488-y  0.332
2021 Moussa S, Murtas G, Pollegioni L, Mauzeroll J. Enhancing Electrochemical Biosensor Selectivity with Engineered d-Amino Acid Oxidase Enzymes for d-Serine and d-Alanine Quantification. Acs Applied Bio Materials. 4: 5598-5604. PMID 35006748 DOI: 10.1021/acsabm.1c00409  0.423
2021 Murtas G, Pollegioni L. D-amino acids as novel blood-based biomarkers. Current Medicinal Chemistry. PMID 34823459 DOI: 10.2174/0929867328666211125092438  0.444
2021 Rosini E, Pollegioni L. Reactive oxygen species as a double-edged sword: The role of oxidative enzymes in antitumor therapy. Biofactors (Oxford, England). PMID 34608689 DOI: 10.1002/biof.1789  0.326
2021 Pollegioni L, Molla G, Sacchi S, Murtas G. Human D-aspartate Oxidase: A Key Player in D-aspartate Metabolism. Frontiers in Molecular Biosciences. 8: 689719. PMID 34250021 DOI: 10.3389/fmolb.2021.689719  0.457
2021 Pollegioni L, Molla G, Sacchi S, Murtas G. Human D-aspartate Oxidase: A Key Player in D-aspartate Metabolism. Frontiers in Molecular Biosciences. 8: 689719. PMID 34250021 DOI: 10.3389/fmolb.2021.689719  0.457
2021 Dallérac G, Li X, Lecouflet P, Morisot N, Sacchi S, Asselot R, Pham TH, Potier B, Watson DJG, Schmidt S, Levasseur G, Fossat P, Besedin A, Rivet JM, Coyle JT, ... ... Pollegioni L, et al. Dopaminergic neuromodulation of prefrontal cortex activity requires the NMDA receptor coagonist d-serine. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34083436 DOI: 10.1073/pnas.2023750118  0.693
2021 Sacchi S, Rabattoni V, Miceli M, Pollegioni L. Yin and Yang in Post-Translational Modifications of Human D-Amino Acid Oxidase. Frontiers in Molecular Biosciences. 8: 684934. PMID 34041270 DOI: 10.3389/fmolb.2021.684934  0.478
2021 Murtas G, Marcone GL, Peracchi A, Zangelmi E, Pollegioni L. Biochemical and Biophysical Characterization of Recombinant Human 3-Phosphoglycerate Dehydrogenase. International Journal of Molecular Sciences. 22. PMID 33921788 DOI: 10.3390/ijms22084231  0.33
2021 Rabattoni V, Pollegioni L, Tedeschi G, Maffioli E, Sacchi S. Cellular studies of the two main isoforms of human D-aspartate oxidase. The Febs Journal. PMID 33650155 DOI: 10.1111/febs.15797  0.36
2021 Piubelli L, Murtas G, Rabattoni V, Pollegioni L. The Role of D-Amino Acids in Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 33554911 DOI: 10.3233/JAD-201217  0.419
2021 Piubelli L, Pollegioni L, Rabattoni V, Mauri M, Princiotta Cariddi L, Versino M, Sacchi S. Serum D-serine levels are altered in early phases of Alzheimer's disease: towards a precocious biomarker. Translational Psychiatry. 11: 77. PMID 33500383 DOI: 10.1038/s41398-021-01202-3  0.304
2021 Murtas G, Sacchi S, Tedeschi G, Maffioli E, Notomista E, Cafaro V, Abbondi M, Mothet JP, Pollegioni L. Antimicrobial D-amino acid oxidase-derived peptides specify gut microbiota. Cellular and Molecular Life Sciences : Cmls. PMID 33484270 DOI: 10.1007/s00018-020-03755-w  0.678
2020 Carenzi G, Sacchi S, Abbondi M, Pollegioni L. Direct chromatographic methods for enantioresolution of amino acids: recent developments. Amino Acids. PMID 32671478 DOI: 10.1007/S00726-020-02873-W  0.489
2020 Deng X, Zhang Y, Chen Z, Kumata K, Van R, Rong J, Shao T, Hatori A, Mori W, Yu Q, Hu K, Fujinaga M, Wey HY, Shao Y, Josephson L, ... ... Pollegioni L, et al. Synthesis and preliminary evaluation of 4-hydroxy-6-(3-[C]methoxyphenethyl)pyridazin-3(2H)-one, a C-labeled d-amino acid oxidase (DAAO) inhibitor for PET imaging. Bioorganic & Medicinal Chemistry Letters. 30: 127326. PMID 32631531 DOI: 10.1016/J.Bmcl.2020.127326  0.316
2020 Murtas G, Sacchi S, Kumar MS, Bosco DA, Pollegioni L. Is the primate-specific protein pLG72 affecting SOD1 functionality and superoxide formation? Free Radical Research. 1-25. PMID 32623917 DOI: 10.1080/10715762.2020.1791335  0.398
2020 Rosini E, D'Antona P, Pollegioni L. Biosensors for D-Amino Acids: Detection Methods and Applications. International Journal of Molecular Sciences. 21. PMID 32605078 DOI: 10.3390/Ijms21134574  0.464
2020 Murtas G, Marcone GL, Sacchi S, Pollegioni L. L-serine synthesis via the phosphorylated pathway in humans. Cellular and Molecular Life Sciences : Cmls. PMID 32594192 DOI: 10.1007/S00018-020-03574-Z  0.438
2020 Puggioni V, Savinelli A, Miceli M, Molla G, Pollegioni L, Sacchi S. Biochemical characterization of mouse d-aspartate oxidase. Biochimica Et Biophysica Acta. Proteins and Proteomics. 1868: 140472. PMID 32553892 DOI: 10.1016/J.Bbapap.2020.140472  0.512
2020 Pollegioni L, Rosini E, Molla G. Advances in Enzymatic Synthesis of D-Amino Acids. International Journal of Molecular Sciences. 21. PMID 32369969 DOI: 10.3390/Ijms21093206  0.506
2020 Molla G, Chaves-Sanjuan A, Savinelli A, Nardini M, Pollegioni L. Structure and kinetic properties of human d-aspartate oxidase, the enzyme-controlling d-aspartate levels in brain. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 34: 1182-1197. PMID 31914658 DOI: 10.1096/Fj.201901703R  0.553
2020 Ocal N, L’enfant M, Charmantray F, Pollegioni L, Martin J, Auffray P, Collin J, Hecquet L. d-Serine as a Key Building Block: Enzymatic Process Development and Smart Applications within the Cascade Enzymatic Concept Organic Process Research & Development. 24: 769-775. DOI: 10.1021/Acs.Oprd.0C00024  0.497
2019 Marcone GL, Binda E, Rosini E, Abbondi M, Pollegioni L. Antibacterial Properties of D-Amino Acid Oxidase: Impact on the Food Industry. Frontiers in Microbiology. 10: 2786. PMID 31849918 DOI: 10.3389/Fmicb.2019.02786  0.479
2019 Marcone GL, Rosini E, Crespi E, Pollegioni L. D-amino acids in foods. Applied Microbiology and Biotechnology. PMID 31832715 DOI: 10.1007/S00253-019-10264-9  0.477
2019 Murtas G, Sacchi S, Pollegioni L. Substitution of Arginine 120 in Human D-Amino Acid Oxidase Favors FAD-Binding and Nuclear Mistargeting. Frontiers in Molecular Biosciences. 6: 125. PMID 31799256 DOI: 10.3389/Fmolb.2019.00125  0.497
2019 Rosini E, Pollegioni L. PEG-DAAO conjugate: A promising tool for cancer therapy optimized by protein engineering. Nanomedicine : Nanotechnology, Biology, and Medicine. 102122. PMID 31706037 DOI: 10.1016/J.Nano.2019.102122  0.445
2019 Rosini E, Pollegioni L. A comprehensive practical laboratory course on protein engineering: Evolution of a glycine oxidase variant active on the herbicide glyphosate. Biochemistry and Molecular Biology Education : a Bimonthly Publication of the International Union of Biochemistry and Molecular Biology. PMID 31444933 DOI: 10.1002/Bmb.21291  0.313
2019 Nuzzo T, Punzo D, Devoto P, Rosini E, Paciotti S, Sacchi S, Li Q, Thiolat ML, Véga C, Carella M, Carta M, Gardoni F, Calabresi P, Pollegioni L, Bezard E, et al. The levels of the NMDA receptor co-agonist D-serine are reduced in the substantia nigra of MPTP-lesioned macaques and in the cerebrospinal fluid of Parkinson's disease patients. Scientific Reports. 9: 8898. PMID 31222058 DOI: 10.1038/S41598-019-45419-1  0.462
2019 Elfgen A, Hupert M, Bochinsky K, Tusche M, González de San Román Martin E, Gering I, Sacchi S, Pollegioni L, Huesgen PF, Hartmann R, Santiago-Schübel B, Kutzsche J, Willbold D. Metabolic resistance of the D-peptide RD2 developed for direct elimination of amyloid-β oligomers. Scientific Reports. 9: 5715. PMID 30952881 DOI: 10.1038/S41598-019-41993-6  0.357
2019 Nuzzo T, Feligioni M, Cristino L, Pagano I, Marcelli S, Iannuzzi F, Imperatore R, D'Angelo L, Petrella C, Carella M, Pollegioni L, Sacchi S, Punzo D, De Girolamo P, Errico F, et al. Free d-aspartate triggers NMDA receptor-dependent cell death in primary cortical neurons and perturbs JNK activation, Tau phosphorylation, and protein SUMOylation in the cerebral cortex of mice lacking d-aspartate oxidase activity. Experimental Neurology. 317: 51-65. PMID 30822420 DOI: 10.1016/J.Expneurol.2019.02.014  0.458
2019 Motta P, Pollegioni L, Molla G. Properties of L-amino acid deaminase: en route to optimize bioconversion reactions. Biochimie. PMID 30673585 DOI: 10.1016/J.Biochi.2019.01.010  0.462
2019 Mothet JP, Billard JM, Pollegioni L, Coyle JT, Sweedler JV. Investigating brain d-serine: advocacy for good practices. Acta Physiologica (Oxford, England). e13257. PMID 30650253 DOI: 10.1111/Apha.13257  0.729
2019 L'enfant M, Bruna F, Lorillière M, Ocal N, Fessner W, Pollegioni L, Charmantray F, Hecquet L. One‐Pot Cascade Synthesis of (3S)‐Hydroxyketones Catalyzed by Transketolase via Hydroxypyruvate Generated in Situ from d‐Serine by d‐Amino Acid Oxidase Advanced Synthesis & Catalysis. 361: 2550-2558. DOI: 10.1002/Adsc.201900109  0.346
2018 Pollegioni L, Sasabe J. Editorial: Bioscience of D-amino Acid Oxidase From Biochemistry to Pathophysiology. Frontiers in Molecular Biosciences. 5: 108. PMID 30547038 DOI: 10.3389/Fmolb.2018.00108  0.517
2018 Pollegioni L, Sacchi S, Murtas G. Human D-Amino Acid Oxidase: Structure, Function, and Regulation. Frontiers in Molecular Biosciences. 5: 107. PMID 30547037 DOI: 10.3389/Fmolb.2018.00107  0.543
2018 Vignali E, Tonin F, Pollegioni L, Rosini E. Characterization and use of a bacterial lignin peroxidase with an improved manganese-oxidative activity. Applied Microbiology and Biotechnology. PMID 30302519 DOI: 10.1007/S00253-018-9409-3  0.333
2018 Raboni S, Revtovich S, Demitri N, Giabbai B, Storici P, Cocconcelli C, Faggiano S, Rosini E, Pollegioni L, Galati S, Buschini A, Morozova E, Kulikova V, Nikulin A, Gabellieri E, et al. Engineering methionine γ-lyase from Citrobacter freundii for anticancer activity. Biochimica Et Biophysica Acta. Proteins and Proteomics. PMID 30268810 DOI: 10.1016/J.Bbapap.2018.09.011  0.388
2018 Cappelletti P, Tallarita E, Rabattoni V, Campomenosi P, Sacchi S, Pollegioni L. Proline oxidase controls proline, glutamate, and glutamine cellular concentrations in a U87 glioblastoma cell line. Plos One. 13: e0196283. PMID 29694413 DOI: 10.1371/Journal.Pone.0196283  0.39
2018 Pollegioni L, Mothet JP, Gianluca M. Special issue on "d-amino acids: biology in the mirror". Biochimica Et Biophysica Acta. PMID 29679765 DOI: 10.1016/J.Bbapap.2018.04.009  0.732
2018 Pollegioni L, Piubelli L, Molla G, Rosini E. D-Amino Acid Oxidase-pLG72 Interaction and D-Serine Modulation. Frontiers in Molecular Biosciences. 5: 3. PMID 29417050 DOI: 10.3389/Fmolb.2018.00003  0.511
2018 Berini F, Verce M, Ausec L, Rosini E, Tonin F, Pollegioni L, Mandić-Mulec I. Isolation and characterization of a heterologously expressed bacterial laccase from the anaerobe Geobacter metallireducens. Applied Microbiology and Biotechnology. PMID 29380032 DOI: 10.1007/S00253-018-8785-Z  0.343
2018 Melis R, Rosini E, Pirillo V, Pollegioni L, Molla G. In vitro evolution of an l-amino acid deaminase active on l-1-naphthylalanine Catalysis Science & Technology. 8: 5359-5367. DOI: 10.1039/C8Cy01380B  0.421
2017 Murtas G, Sacchi S, Valentino M, Pollegioni L. Biochemical Properties of Human D-Amino Acid Oxidase. Frontiers in Molecular Biosciences. 4: 88. PMID 29326945 DOI: 10.3389/Fmolb.2017.00088  0.566
2017 Murtas G, Caldinelli L, Cappelletti P, Sacchi S, Pollegioni L. Human d-amino acid oxidase: The inactive G183R variant. Biochimica Et Biophysica Acta. PMID 29274788 DOI: 10.1016/J.Bbapap.2017.12.007  0.508
2017 Molla G, Melis R, Pollegioni L. Breaking the mirror: l-Amino acid deaminase, a novel stereoselective biocatalyst. Biotechnology Advances. PMID 28782586 DOI: 10.1016/J.Biotechadv.2017.07.011  0.465
2017 Bavaro T, Tengattini S, Piubelli L, Mangione F, Bernardini R, Monzillo V, Calarota S, Marone P, Amicosante M, Pollegioni L, Temporini C, Terreni M. Glycosylation of Recombinant Antigenic Proteins from Mycobacterium tuberculosis: In Silico Prediction of Protein Epitopes and Ex Vivo Biological Evaluation of New Semi-Synthetic Glycoconjugates. Molecules (Basel, Switzerland). 22. PMID 28661444 DOI: 10.3390/Molecules22071081  0.302
2017 Ferreira JS, Papouin T, Ladépêche L, Yao A, Langlais VC, Bouchet D, Dulong J, Mothet JP, Sacchi S, Pollegioni L, Paoletti P, Oliet SHR, Groc L. Co-agonists differentially tune GluN2B-NMDA receptor trafficking at hippocampal synapses. Elife. 6. PMID 28598327 DOI: 10.7554/Elife.25492  0.693
2017 Nuzzo T, Sacchi S, Errico F, Keller S, Palumbo O, Florio E, Punzo D, Napolitano F, Copetti M, Carella M, Chiariotti L, Bertolino A, Pollegioni L, Usiello A. Decreased free d-aspartate levels are linked to enhanced d-aspartate oxidase activity in the dorsolateral prefrontal cortex of schizophrenia patients. Npj Schizophrenia. 3: 16. PMID 28560262 DOI: 10.1038/s41537-017-0015-7  0.389
2017 Van Horn MR, Strasser A, Miraucourt LS, Pollegioni L, Ruthazer ES. The gliotransmitter D-serine promotes synapse maturation and axonal stabilization in vivo. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 28550169 DOI: 10.1523/Jneurosci.3158-16.2017  0.456
2017 Luks L, Maier MY, Sacchi S, Pollegioni L, Dietrich DR. Understanding renal nuclear protein accumulation: an in vitro approach to explain an in vivo phenomenon. Archives of Toxicology. PMID 28451739 DOI: 10.1007/S00204-017-1970-5  0.322
2017 Sacchi S, Novellis V, Paolone G, Nuzzo T, Iannotta M, Belardo C, Squillace M, Bolognesi P, Rosini E, Motta Z, Frassineti M, Bertolino A, Pollegioni L, Morari M, Maione S, et al. Olanzapine, but not clozapine, increases glutamate release in the prefrontal cortex of freely moving mice by inhibiting D-aspartate oxidase activity. Scientific Reports. 7: 46288. PMID 28393897 DOI: 10.1038/Srep46288  0.445
2017 Casciello C, Tonin F, Berini F, Fasoli E, Marinelli F, Pollegioni L, Rosini E. A valuable peroxidase activity from the novel species Nonomuraea gerenzanensis growing on alkali lignin. Biotechnology Reports (Amsterdam, Netherlands). 13: 49-57. PMID 28352563 DOI: 10.1016/J.Btre.2016.12.005  0.34
2017 Sacchi S, Cappelletti P, Pirone L, Smaldone G, Pedone E, Pollegioni L. Elucidating the role of the pLG72 R30K substitution in schizophrenia susceptibility. Febs Letters. PMID 28166363 DOI: 10.1002/1873-3468.12585  0.473
2017 Ferreira JS, Papouin T, Ladépêche L, Yao A, Langlais VC, Bouchet D, Dulong J, Mothet J, Sacchi S, Pollegioni L, Paoletti P, Oliet SHR, Groc L. Author response: Co-agonists differentially tune GluN2B-NMDA receptor trafficking at hippocampal synapses Elife. DOI: 10.7554/Elife.25492.016  0.633
2017 Elfgen A, Santiago-Schübel B, Sacchi S, Pollegioni L, Kutzsche J, Willbold D. SURPRISINGLY HIGH RESISTANCE OF Aβ OLIGOMER ELIMINATING ALL-D-ENANTIOMERIC PEPTIDES AGAINST METABOLIZATION BY ENZYMES CONTAINED IN THE GASTROINTESTINAL TRACT, BLOOD, LIVER AND BRAIN Alzheimer's & Dementia. 13: P1575. DOI: 10.1016/J.Jalz.2017.07.743  0.337
2017 Rosini E, Melis R, Molla G, Tessaro D, Pollegioni L. Deracemization and Stereoinversion of α-Amino Acids byl-Amino Acid Deaminase Advanced Synthesis & Catalysis. 359: 3773-3781. DOI: 10.1002/Adsc.201700806  0.471
2016 Birolo L, Sacchi S, Smaldone G, Molla G, Leo G, Caldinelli L, Pirone L, Eliometri P, Di Gaetano S, Orefice I, Pedone E, Pucci P, Pollegioni L. Regulating levels of the neuromodulator D-serine in human brain: structural insight into pLG72 and D-amino acid oxidase interaction. The Febs Journal. PMID 27400736 DOI: 10.1111/Febs.13809  0.471
2016 Tonin F, Rosini E, Piubelli L, Sanchez-Amat A, Pollegioni L. Different recombinant forms of polyphenol oxidase A, a laccase from Marinomonas mediterranea. Protein Expression and Purification. PMID 27050199 DOI: 10.1016/J.Pep.2016.03.011  0.367
2016 Motta P, Molla G, Pollegioni L, Nardini M. Structure-Function Relationships in L-Amino Acid Deaminase, a Flavoprotein Belonging to a Novel Class of Biotechnologically Relevant Enzymes. The Journal of Biological Chemistry. PMID 27022028 DOI: 10.1074/Jbc.M115.703819  0.437
2016 Meunier CN, Dallérac G, Le Roux N, Sacchi S, Levasseur G, Amar M, Pollegioni L, Mothet JP, Fossier P. D-Serine and Glycine Differentially Control Neurotransmission during Visual Cortex Critical Period. Plos One. 11: e0151233. PMID 27003418 DOI: 10.1371/Journal.Pone.0151233  0.706
2016 Luks L, Sacchi S, Pollegioni L, Dietrich DR. Novel insights into renal D-amino acid oxidase accumulation: propiverine changes DAAO localization and peroxisomal size in vivo. Archives of Toxicology. PMID 26961980 DOI: 10.1007/S00204-016-1685-Z  0.356
2016 Punzo D, Errico F, Cristino L, Sacchi S, Keller S, Belardo C, Luongo L, Nuzzo T, Imperatore R, Florio E, De Novellis V, Affinito O, Migliarini S, Maddaloni G, Sisalli MJ, ... ... Pollegioni L, et al. Age-Related Changes in d-Aspartate Oxidase Promoter Methylation Control Extracellular d-Aspartate Levels and Prevent Precocious Cell Death during Brain Aging. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 3064-78. PMID 26961959 DOI: 10.1523/Jneurosci.3881-15.2016  0.447
2016 Sacchi S, Binelli G, Pollegioni L. G72 primate-specific gene: a still enigmatic element in psychiatric disorders. Cellular and Molecular Life Sciences : Cmls. PMID 26914235 DOI: 10.1007/S00018-016-2165-6  0.367
2016 Tonin F, Melis R, Cordes A, Sanchez-Amat A, Pollegioni L, Rosini E. Comparison of different microbial laccases as tools for industrial uses. New Biotechnology. PMID 26844639 DOI: 10.1016/J.Nbt.2016.01.007  0.322
2016 Rosini E, D'Arrigo P, Pollegioni L. Demethylation of vanillic acid by recombinant LigM in a one-pot cofactor regeneration system Catalysis Science & Technology. 6: 7729-7737. DOI: 10.1039/C6Cy01402J  0.38
2015 Cappellini F, Recordati C, Maglie M, Pollegioni L, Rossi F, Daturi M, Gornati R, Bernardini G. New synthesis and biodistribution of the D-amino acid oxidase-magnetic nanoparticle system. Future Science Oa. 1: FSO67. PMID 28031918 DOI: 10.4155/Fso.15.67  0.391
2015 Terry-Lorenzo RT, Masuda K, Sugao K, Fang QK, Orsini MA, Sacchi S, Pollegioni L. High-Throughput Screening Strategy Identifies Allosteric, Covalent Human D-Amino Acid Oxidase Inhibitor. Journal of Biomolecular Screening. PMID 26296926 DOI: 10.1177/1087057115600413  0.367
2015 Cappelletti P, Piubelli L, Murtas G, Caldinelli L, Valentino M, Molla G, Pollegioni L, Sacchi S. Structure-function relationships in human d-amino acid oxidase variants corresponding to known SNPs. Biochimica Et Biophysica Acta. 1854: 1150-9. PMID 25701391 DOI: 10.1016/J.Bbapap.2015.02.005  0.535
2015 Pollegioni L, Tonin F, Rosini E. Lignin-degrading enzymes. The Febs Journal. 282: 1190-213. PMID 25649492 DOI: 10.1111/Febs.13224  0.328
2015 Le Bail M, Martineau M, Sacchi S, Yatsenko N, Radzishevsky I, Conrod S, Ait Ouares K, Wolosker H, Pollegioni L, Billard JM, Mothet JP. Identity of the NMDA receptor coagonist is synapse specific and developmentally regulated in the hippocampus. Proceedings of the National Academy of Sciences of the United States of America. 112: E204-13. PMID 25550512 DOI: 10.1073/Pnas.1416668112  0.704
2015 Conti G, Pollegioni L, Rosini E. One-pot conversion of cephalosporin C by using an optimized two-enzyme process Catalysis Science and Technology. 5: 1854-1863. DOI: 10.1039/C4Cy01522C  0.356
2015 D'Arrigo P, Allegretti C, Fiorati A, Piubelli L, Rosini E, Tessaro D, Valentino M, Pollegioni L. Immobilization of L-aspartate oxidase from Sulfolobus tokodaii as a biocatalyst for resolution of aspartate solutions Catalysis Science and Technology. 5: 1106-1114. DOI: 10.1039/C4Cy00968A  0.399
2014 Temporini C, Bavaro T, Tengattini S, Serra I, Marrubini G, Calleri E, Fasanella F, Piubelli L, Marinelli F, Pollegioni L, Speranza G, Massolini G, Terreni M. Liquid chromatography-mass spectrometry structural characterization of neo glycoproteins aiding the rational design and synthesis of a novel glycovaccine for protection against tuberculosis. Journal of Chromatography. A. 1367: 57-67. PMID 25282312 DOI: 10.1016/J.Chroma.2014.09.041  0.322
2014 Molla G, Nardini M, Motta P, D'Arrigo P, Panzeri W, Pollegioni L. Aminoacetone oxidase from Streptococcus oligofermentans belongs to a new three-domain family of bacterial flavoproteins. The Biochemical Journal. 464: 387-99. PMID 25269103 DOI: 10.1042/Bj20140972  0.375
2014 Labarrière M, Thomas F, Dutar P, Pollegioni L, Wolosker H, Billard JM. Circuit-specific changes in D-serine-dependent activation of the N-methyl-D-aspartate receptor in the aging hippocampus. Age (Dordrecht, Netherlands). 36: 9698. PMID 25138794 DOI: 10.1007/S11357-014-9698-0  0.403
2014 Terry-Lorenzo RT, Chun LE, Brown SP, Heffernan ML, Fang QK, Orsini MA, Pollegioni L, Hardy LW, Spear KL, Large TH. Novel human D-amino acid oxidase inhibitors stabilize an active-site lid-open conformation. Bioscience Reports. 34. PMID 25001371 DOI: 10.1042/Bsr20140071  0.467
2014 Rosini E, Piubelli L, Molla G, Frattini L, Valentino M, Varriale A, D'Auria S, Pollegioni L. Novel biosensors based on optimized glycine oxidase. The Febs Journal. 281: 3460-72. PMID 24925096 DOI: 10.1111/Febs.12873  0.343
2014 Canu N, Ciotti MT, Pollegioni L. Serine racemase: a key player in apoptosis and necrosis. Frontiers in Synaptic Neuroscience. 6: 9. PMID 24795622 DOI: 10.3389/Fnsyn.2014.00009  0.34
2014 Lench AM, Massey PV, Pollegioni L, Woodhall GL, Jones RS. Astroglial d-serine is the endogenous co-agonist at the presynaptic NMDA receptor in rat entorhinal cortex. Neuropharmacology. 83: 118-27. PMID 24747728 DOI: 10.1016/J.Neuropharm.2014.04.004  0.46
2014 Conti G, Pollegioni L, Molla G, Rosini E. Strategic manipulation of an industrial biocatalyst--evolution of a cephalosporin C acylase. The Febs Journal. 281: 2443-55. PMID 24684708 DOI: 10.1111/Febs.12798  0.356
2014 Polcari D, Kwan A, Van Horn MR, Danis L, Pollegioni L, Ruthazer ES, Mauzeroll J. Disk-shaped amperometric enzymatic biosensor for in vivo detection of D-serine. Analytical Chemistry. 86: 3501-7. PMID 24650010 DOI: 10.1021/Ac404111U  0.493
2014 Cappelletti P, Campomenosi P, Pollegioni L, Sacchi S. The degradation (by distinct pathways) of human D-amino acid oxidase and its interacting partner pLG72--two key proteins in D-serine catabolism in the brain. The Febs Journal. 281: 708-23. PMID 24237903 DOI: 10.1111/Febs.12616  0.513
2014 Rosini E, Tonin F, Vasylieva N, Marinesco S, Pollegioni L. Evolution of histamine oxidase activity for biotechnological applications. Applied Microbiology and Biotechnology. 98: 739-48. PMID 23995223 DOI: 10.1007/S00253-013-5159-4  0.304
2014 Dallerac G, Tupin F, Morisot N, Levasseur G, Sacchi S, Fossat P, Rivet J, Oliet S, Coyle J, Pollegioni L, Snyder S, Contarino A, Millan M, Mothet J. S.12.02 Absence of D-serine results in abnormal dopamine–glutamate dialogue in the prefrontal cortex European Neuropsychopharmacology. 24: S126. DOI: 10.1016/S0924-977X(14)70161-0  0.35
2013 Pollegioni L, Motta P, Molla G. L-amino acid oxidase as biocatalyst: a dream too far? Applied Microbiology and Biotechnology. 97: 9323-41. PMID 24077723 DOI: 10.1007/S00253-013-5230-1  0.447
2013 Hopkins SC, Heffernan ML, Saraswat LD, Bowen CA, Melnick L, Hardy LW, Orsini MA, Allen MS, Koch P, Spear KL, Foglesong RJ, Soukri M, Chytil M, Fang QK, Jones SW, ... ... Pollegioni L, et al. Structural, kinetic, and pharmacodynamic mechanisms of D-amino acid oxidase inhibition by small molecules. Journal of Medicinal Chemistry. 56: 3710-24. PMID 23631755 DOI: 10.1021/Jm4002583  0.505
2013 Li Y, Sacchi S, Pollegioni L, Basu AC, Coyle JT, Bolshakov VY. Identity of endogenous NMDAR glycine site agonist in amygdala is determined by synaptic activity level. Nature Communications. 4: 1760. PMID 23612301 DOI: 10.1038/Ncomms2779  0.428
2013 Maucler C, Pernot P, Vasylieva N, Pollegioni L, Marinesco S. In vivo D-serine hetero-exchange through alanine-serine-cysteine (ASC) transporters detected by microelectrode biosensors. Acs Chemical Neuroscience. 4: 772-81. PMID 23581544 DOI: 10.1021/Cn4000549  0.501
2013 Curcio L, Podda MV, Leone L, Piacentini R, Mastrodonato A, Cappelletti P, Sacchi S, Pollegioni L, Grassi C, D'Ascenzo M. Reduced D-serine levels in the nucleus accumbens of cocaine-treated rats hinder the induction of NMDA receptor-dependent synaptic plasticity. Brain : a Journal of Neurology. 136: 1216-30. PMID 23518710 DOI: 10.1093/Brain/Awt036  0.45
2013 Binda E, Marcone GL, Berini F, Pollegioni L, Marinelli F. Streptomyces spp. as efficient expression system for a D,D-peptidase/D,D-carboxypeptidase involved in glycopeptide antibiotic resistance. Bmc Biotechnology. 13: 24. PMID 23497129 DOI: 10.1186/1472-6750-13-24  0.367
2013 Pollegioni L, Rosini E, Molla G. Cephalosporin C acylase: dream and(/or) reality. Applied Microbiology and Biotechnology. 97: 2341-55. PMID 23417342 DOI: 10.1007/S00253-013-4741-0  0.396
2013 Bava A, Gornati R, Cappellini F, Caldinelli L, Pollegioni L, Bernardini G. D-amino acid oxidase-nanoparticle system: a potential novel approach for cancer enzymatic therapy. Nanomedicine (London, England). 8: 1797-806. PMID 23384700 DOI: 10.2217/Nnm.12.187  0.335
2013 Golden E, Paterson R, Tie WJ, Anandan A, Flematti G, Molla G, Rosini E, Pollegioni L, Vrielink A. Structure of a class III engineered cephalosporin acylase: comparisons with class I acylase and implications for differences in substrate specificity and catalytic activity. The Biochemical Journal. 451: 217-26. PMID 23373797 DOI: 10.1042/Bj20121715  0.394
2013 Bifulco D, Pollegioni L, Tessaro D, Servi S, Molla G. A thermostable L-aspartate oxidase: a new tool for biotechnological applications. Applied Microbiology and Biotechnology. 97: 7285-95. PMID 23371294 DOI: 10.1007/S00253-013-4688-1  0.45
2013 Caldinelli L, Sacchi S, Molla G, Nardini M, Pollegioni L. Characterization of human DAAO variants potentially related to an increased risk of schizophrenia. Biochimica Et Biophysica Acta. 1832: 400-10. PMID 23219954 DOI: 10.1016/J.Bbadis.2012.11.019  0.49
2013 Sacchi S, Rosini E, Pollegioni L, Molla G. D-amino acid oxidase inhibitors as a novel class of drugs for schizophrenia therapy. Current Pharmaceutical Design. 19: 2499-511. PMID 23116391 DOI: 10.2174/1381612811319140002  0.491
2012 Sacchi S, Caldinelli L, Cappelletti P, Pollegioni L, Molla G. Structure-function relationships in human D-amino acid oxidase. Amino Acids. 43: 1833-50. PMID 22865246 DOI: 10.1007/S00726-012-1345-4  0.564
2012 Papouin T, Ladépêche L, Ruel J, Sacchi S, Labasque M, Hanini M, Groc L, Pollegioni L, Mothet JP, Oliet SH. Synaptic and extrasynaptic NMDA receptors are gated by different endogenous coagonists. Cell. 150: 633-46. PMID 22863013 DOI: 10.1016/J.Cell.2012.06.029  0.69
2012 Binda E, Marcone GL, Pollegioni L, Marinelli F. Characterization of VanYn, a novel D,D-peptidase/D,D-carboxypeptidase involved in glycopeptide antibiotic resistance in Nonomuraea sp. ATCC 39727. The Febs Journal. 279: 3203-13. PMID 22788848 DOI: 10.1111/J.1742-4658.2012.08706.X  0.46
2012 Esposito S, Pristerà A, Maresca G, Cavallaro S, Felsani A, Florenzano F, Manni L, Ciotti MT, Pollegioni L, Borsello T, Canu N. Contribution of serine racemase/d-serine pathway to neuronal apoptosis. Aging Cell. 11: 588-98. PMID 22507034 DOI: 10.1111/J.1474-9726.2012.00822.X  0.372
2012 Pernot P, Maucler C, Tholance Y, Vasylieva N, Debilly G, Pollegioni L, Cespuglio R, Marinesco S. d-Serine diffusion through the blood-brain barrier: effect on d-serine compartmentalization and storage. Neurochemistry International. 60: 837-45. PMID 22465696 DOI: 10.1016/J.Neuint.2012.03.008  0.454
2012 Tallarita E, Pollegioni L, Servi S, Molla G. Expression in Escherichia coli of the catalytic domain of human proline oxidase. Protein Expression and Purification. 82: 345-51. PMID 22333530 DOI: 10.1016/J.Pep.2012.01.021  0.318
2012 Tedeschi G, Pollegioni L, Negri A. Assays of D-amino acid oxidases. Methods in Molecular Biology (Clifton, N.J.). 794: 381-95. PMID 21956578 DOI: 10.1007/978-1-61779-331-8_26  0.546
2012 Sacchi S, Rosini E, Caldinelli L, Pollegioni L. Biosensors for D-amino acid detection. Methods in Molecular Biology (Clifton, N.J.). 794: 313-24. PMID 21956573 DOI: 10.1007/978-1-61779-331-8_21  0.528
2012 Fossat P, Turpin FR, Sacchi S, Dulong J, Shi T, Rivet JM, Sweedler JV, Pollegioni L, Millan MJ, Oliet SH, Mothet JP. Glial D-serine gates NMDA receptors at excitatory synapses in prefrontal cortex. Cerebral Cortex (New York, N.Y. : 1991). 22: 595-606. PMID 21690263 DOI: 10.1093/Cercor/Bhr130  0.739
2012 Rosini E, Nossa S, Valentino M, D'Arrigo P, Marinesco S, Pollegioni L. Expression of rat diamine oxidase in Escherichia coli Journal of Molecular Catalysis B: Enzymatic. 82: 115-120. DOI: 10.1016/J.Molcatb.2012.06.014  0.301
2012 Rosini E, Monelli CS, Pollegioni L, Riva S, Monti D. On the substrate preference of glutaryl acylases Journal of Molecular Catalysis B: Enzymatic. 76: 52-58. DOI: 10.1016/J.Molcatb.2011.12.001  0.313
2011 Volontè F, Pisanelli I, D'Arrigo P, Viani F, Molla G, Servi S, Pollegioni L. Overexpression of a bacterial chymotrypsin: application for L-amino acid ester hydrolysis. Enzyme and Microbial Technology. 49: 560-6. PMID 22142732 DOI: 10.1016/J.Enzmictec.2011.06.009  0.374
2011 Frattini LF, Piubelli L, Sacchi S, Molla G, Pollegioni L. Is rat an appropriate animal model to study the involvement of D-serine catabolism in schizophrenia? Insights from characterization of D-amino acid oxidase. The Febs Journal. 278: 4362-73. PMID 21981077 DOI: 10.1111/J.1742-4658.2011.08354.X  0.477
2011 Ghisla S, Pollegioni L, Molla G. Revisitation of the βCl-elimination reaction of D-amino acid oxidase: new interpretation of the reaction that sparked flavoprotein dehydrogenation mechanisms. The Journal of Biological Chemistry. 286: 40987-98. PMID 21949129 DOI: 10.1074/Jbc.M111.266536  0.385
2011 Sacchi S, Cappelletti P, Giovannardi S, Pollegioni L. Evidence for the interaction of D-amino acid oxidase with pLG72 in a glial cell line. Molecular and Cellular Neurosciences. 48: 20-8. PMID 21679769 DOI: 10.1016/J.Mcn.2011.06.001  0.488
2011 Pollegioni L, Schonbrunn E, Siehl D. Molecular basis of glyphosate resistance-different approaches through protein engineering. The Febs Journal. 278: 2753-66. PMID 21668647 DOI: 10.1111/J.1742-4658.2011.08214.X  0.32
2011 Vasylieva N, Barnych B, Meiller A, Maucler C, Pollegioni L, Lin JS, Barbier D, Marinesco S. Covalent enzyme immobilization by poly(ethylene glycol) diglycidyl ether (PEGDE) for microelectrode biosensor preparation. Biosensors & Bioelectronics. 26: 3993-4000. PMID 21546239 DOI: 10.1016/J.Bios.2011.03.012  0.37
2011 Frattini L, Rosini E, Pollegioni L, Pilone MS. Analyzing the D-amino acid content in biological samples by engineered enzymes. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 879: 3235-9. PMID 21419721 DOI: 10.1016/J.Jchromb.2011.02.036  0.522
2011 Pollegioni L, Molla G. New biotech applications from evolved D-amino acid oxidases. Trends in Biotechnology. 29: 276-83. PMID 21397351 DOI: 10.1016/J.Tibtech.2011.01.010  0.493
2011 Rosini E, Molla G, Ghisla S, Pollegioni L. On the reaction of D-amino acid oxidase with dioxygen: O2 diffusion pathways and enhancement of reactivity. The Febs Journal. 278: 482-92. PMID 21182588 DOI: 10.1111/J.1742-4658.2010.07969.X  0.37
2011 Curcio L, Leone L, Podda MV, Sacchi S, Pollegioni L, Grassi C, D'Ascenzo M. P22.13 Glia-derived D-serine control of synaptic plasticity in the nucleus accumbens: possible role for astrocytes in drug addiction Clinical Neurophysiology. 122. DOI: 10.1016/S1388-2457(11)60574-9  0.349
2010 Caldinelli L, Molla G, Bracci L, Lelli B, Pileri S, Cappelletti P, Sacchi S, Pollegioni L. Effect of ligand binding on human D-amino acid oxidase: implications for the development of new drugs for schizophrenia treatment. Protein Science : a Publication of the Protein Society. 19: 1500-12. PMID 20521334 DOI: 10.1002/Pro.429  0.484
2010 Saam J, Rosini E, Molla G, Schulten K, Pollegioni L, Ghisla S. O2 reactivity of flavoproteins: dynamic access of dioxygen to the active site and role of a H+ relay system in D-amino acid oxidase. The Journal of Biological Chemistry. 285: 24439-46. PMID 20498362 DOI: 10.1074/Jbc.M110.131193  0.401
2010 Pollegioni L, Sacchi S. Metabolism of the neuromodulator D-serine. Cellular and Molecular Life Sciences : Cmls. 67: 2387-404. PMID 20195697 DOI: 10.1007/S00018-010-0307-9  0.54
2010 Binda E, Marcone G, Beltrametti F, Pollegioni L, Molla G, Servi S. Biotechnological potential of VanY, a D,D-carboxypeptidase from Nonomuraea sp. ATCC 39727 Journal of Biotechnology. 150: 382-382. DOI: 10.1016/J.Jbiotec.2010.09.475  0.422
2009 Pedotti M, Rosini E, Molla G, Moschetti T, Savino C, Vallone B, Pollegioni L. Glyphosate resistance by engineering the flavoenzyme glycine oxidase. The Journal of Biological Chemistry. 284: 36415-23. PMID 19864430 DOI: 10.1074/Jbc.M109.051631  0.426
2009 Pollegioni L. Cholesterol oxidase: a model flavoprotein oxidase and a biotechnological tool. The Febs Journal. 276: 6825. PMID 19843170 DOI: 10.1111/J.1742-4658.2009.07376.X  0.343
2009 Caldinelli L, Pedotti M, Motteran L, Molla G, Pollegioni L. FAD binding in glycine oxidase from Bacillus subtilis. Biochimie. 91: 1499-508. PMID 19751796 DOI: 10.1016/J.Biochi.2009.09.003  0.32
2009 Rosini E, Pollegioni L, Ghisla S, Orru R, Molla G. Optimization of D-amino acid oxidase for low substrate concentrations--towards a cancer enzyme therapy. The Febs Journal. 276: 4921-32. PMID 19694805 DOI: 10.1111/J.1742-4658.2009.07191.X  0.424
2009 Donini S, Ferrari M, Fedeli C, Faini M, Lamberto I, Marletta AS, Mellini L, Panini M, Percudani R, Pollegioni L, Caldinelli L, Petrucco S, Peracchi A. Recombinant production of eight human cytosolic aminotransferases and assessment of their potential involvement in glyoxylate metabolism. The Biochemical Journal. 422: 265-72. PMID 19545238 DOI: 10.1042/Bj20090748  0.404
2009 Romano D, Molla G, Pollegioni L, Marinelli F. Optimization of human D-amino acid oxidase expression in Escherichia coli. Protein Expression and Purification. 68: 72-8. PMID 19497370 DOI: 10.1016/J.Pep.2009.05.013  0.399
2009 Caldinelli L, Molla G, Sacchi S, Pilone MS, Pollegioni L. Relevance of weak flavin binding in human D-amino acid oxidase. Protein Science : a Publication of the Protein Society. 18: 801-10. PMID 19309736 DOI: 10.1002/Pro.86  0.518
2009 Pedotti M, Ghisla S, Motteran L, Molla G, Pollegioni L. Catalytic and redox properties of glycine oxidase from Bacillus subtilis. Biochimie. 91: 604-12. PMID 19254749 DOI: 10.1016/J.Biochi.2009.02.007  0.358
2009 Molla G, Caldinelli L, Sacchi S, Pollegioni L. Modulation of the activity and stability of human d-amino acid oxidase by the interaction with small ligands New Biotechnology. 25: S11. DOI: 10.1016/J.Nbt.2009.06.030  0.444
2008 Rosini E, Molla G, Rossetti C, Pilone MS, Pollegioni L, Sacchi S. A biosensor for all D-amino acids using evolved D-amino acid oxidase. Journal of Biotechnology. 135: 377-84. PMID 18588925 DOI: 10.1016/J.Jbiotec.2008.06.001  0.525
2008 Volontè F, Marinelli F, Gastaldo L, Sacchi S, Pilone MS, Pollegioni L, Molla G. Optimization of glutaryl-7-aminocephalosporanic acid acylase expression in E. coli. Protein Expression and Purification. 61: 131-7. PMID 18586517 DOI: 10.1016/J.Pep.2008.05.010  0.327
2008 Sacchi S, Bernasconi M, Martineau M, Mothet JP, Ruzzene M, Pilone MS, Pollegioni L, Molla G. pLG72 modulates intracellular D-serine levels through its interaction with D-amino acid oxidase: effect on schizophrenia susceptibility. The Journal of Biological Chemistry. 283: 22244-56. PMID 18544534 DOI: 10.1074/Jbc.M709153200  0.751
2008 Pernot P, Mothet JP, Schuvailo O, Soldatkin A, Pollegioni L, Pilone M, Adeline MT, Cespuglio R, Marinesco S. Characterization of a yeast D-amino acid oxidase microbiosensor for D-serine detection in the central nervous system. Analytical Chemistry. 80: 1589-97. PMID 18229946 DOI: 10.1021/Ac702230W  0.749
2008 Caldinelli L, Iametti S, Barbiroli A, Fessas D, Bonomi F, Piubelli L, Molla G, Pollegioni L. Relevance of the flavin binding to the stability and folding of engineered cholesterol oxidase containing noncovalently bound FAD. Protein Science : a Publication of the Protein Society. 17: 409-19. PMID 18218720 DOI: 10.1110/Ps.073137708  0.325
2008 Pollegioni L, Molla G, Sacchi S, Rosini E, Verga R, Pilone MS. Properties and applications of microbial D-amino acid oxidases: current state and perspectives. Applied Microbiology and Biotechnology. 78: 1-16. PMID 18084756 DOI: 10.1007/S00253-007-1282-4  0.497
2008 Caligiuri A, D'Arrigo P, Rosini E, Pedrocchi-Fantoni G, Tessaro D, Molla G, Servi S, Pollegioni L. Activity of yeast d-amino acid oxidase on aromatic unnatural amino acids Journal of Molecular Catalysis B: Enzymatic. 50: 93-98. DOI: 10.1016/J.Molcatb.2007.09.014  0.506
2008 Caligiuri A, D'Arrigo P, Rosini E, Pedrocchi-Fantoni G, Tessaro D, Molla G, Servi S, Pollegioni L. Activity of yeast d-amino acid oxidase on aromatic unnatural amino acids Journal of Molecular Catalysis B: Enzymatic. 50: 93-98. DOI: 10.1016/j.molcatb.2007.09.014  0.389
2007 Pollegioni L, Sacchi S, Caldinelli L, Boselli A, Pilone MS, Piubelli L, Molla G. Engineering the properties of D-amino acid oxidases by a rational and a directed evolution approach. Current Protein & Peptide Science. 8: 600-18. PMID 18220846 DOI: 10.2174/138920307783018677  0.532
2007 Boselli A, Rosini E, Marcone GL, Sacchi S, Motteran L, Pilone MS, Pollegioni L, Molla G. Glycine oxidase from Bacillus subtilis: role of histidine 244 and methionine 261. Biochimie. 89: 1372-80. PMID 17573175 DOI: 10.1016/J.Biochi.2007.04.019  0.322
2007 Pollegioni L, Piubelli L, Sacchi S, Pilone MS, Molla G. Physiological functions of D-amino acid oxidases: from yeast to humans. Cellular and Molecular Life Sciences : Cmls. 64: 1373-94. PMID 17396222 DOI: 10.1007/S00018-007-6558-4  0.508
2007 Boselli A, Piubelli L, Molla G, Pilone MS, Pollegioni L, Sacchi S. Investigating the role of active site residues of Rhodotorula gracilis D-amino acid oxidase on its substrate specificity. Biochimie. 89: 360-8. PMID 17145127 DOI: 10.1016/J.Biochi.2006.10.017  0.535
2007 Pernot P, Mothet JP, Schuvailo O, Soldatkin A, Pollegioni L, Pilone M, Cespugijo R, Marinesco S. Characterization of a D-amino acid oxidase microbiosensor for D- serine detection in the central nervous system Transducers and Eurosensors '07 - 4th International Conference On Solid-State Sensors, Actuators and Microsystems. 99-101. DOI: 10.1109/SENSOR.2007.4300081  0.723
2007 Pernot P, Mothet JP, Schuvailo O, Soldatkin A, Pollegioni L, Pilone M, Cespugijo R, Marinesco S. Characterization of a D-amino acid oxidase microbiosensor for D- serine detection in the central nervous system Transducers and Eurosensors '07 - 4th International Conference On Solid-State Sensors, Actuators and Microsystems. 99-101. DOI: 10.1109/SENSOR.2007.4300081  0.424
2007 Caldinelli L, Motteran L, Sacchi S, Piubelli L, Boselli A, Mothet JP, Pollegioni L, Pilone MS. Detection of D-amino acids by D-amino acid oxidase D-Amino Acids: a New Frontier in Amino Acid and Protein Research - Practical Methods and Protocols. 135-148.  0.718
2007 Molla G, Rosini E, Marcone GL, Lorenzi S, Pilone MS, Pollegioni L. Techniques for the engineering of D-Amino acid oxidase substrate specificity D-Amino Acids: a New Frontier in Amino Acid and Protein Research - Practical Methods and Protocols. 491-501.  0.359
2006 Lim L, Molla G, Guinn N, Ghisla S, Pollegioni L, Vrielink A. Structural and kinetic analyses of the H121A mutant of cholesterol oxidase. The Biochemical Journal. 400: 13-22. PMID 16856877 DOI: 10.1042/Bj20060664  0.333
2006 Panatier A, Theodosis DT, Mothet JP, Touquet B, Pollegioni L, Poulain DA, Oliet SH. Glia-derived D-serine controls NMDA receptor activity and synaptic memory. Cell. 125: 775-84. PMID 16713567 DOI: 10.1016/J.Cell.2006.02.051  0.693
2006 Molla G, Sacchi S, Bernasconi M, Pilone MS, Fukui K, Pollegioni L. Characterization of human d-amino acid oxidase Febs Letters. 580: 2358-2364. PMID 16616139 DOI: 10.1016/J.Febslet.2006.03.045  0.529
2006 Molla G, Sacchi S, Bernasconi M, Pilone MS, Fukui K, Pollegioni L. Characterization of human d-amino acid oxidase Febs Letters. 580: 2358-2364. PMID 16616139 DOI: 10.1016/j.febslet.2006.03.045  0.398
2006 Caldinelli L, Molla G, Pilone MS, Pollegioni L. Tryptophan 243 affects interprotein contacts, cofactor binding and stability in D-amino acid oxidase from Rhodotorula gracilis. The Febs Journal. 273: 504-12. PMID 16420474 DOI: 10.1111/J.1742-4658.2005.05083.X  0.426
2006 Molla G, Bernasconi M, Sacchi S, Pilone MS, Pollegioni L. Expression in Escherichia coli and in vitro refolding of the human protein pLG72. Protein Expression and Purification. 46: 150-5. PMID 16183301 DOI: 10.1016/J.Pep.2005.08.003  0.453
2006 Caligiuri A, D'Arrigo P, Gefflaut T, Molla G, Pollegioni L, Rosini E, Rossi C, Servi S. Multistep enzyme catalysed deracemisation of 2-naphthyl alanine Biocatalysis and Biotransformation. 24: 409-413. DOI: 10.1080/10242420601033878  0.468
2006 Sacchi S, Boselli A, Job V, Pilone MS, Pollegioni L, Molla G. The role of tyrosines 223 and 238 in Rhodotorula gracilis D-amino acid oxidase catalysis: Interpretation of double mutations Enzyme and Microbial Technology. 38: 795-802. DOI: 10.1016/J.Enzmictec.2005.08.023  0.461
2006 Sacchi S, Boselli A, Job V, Pilone MS, Pollegioni L, Molla G. The role of tyrosines 223 and 238 in Rhodotorula gracilis D-amino acid oxidase catalysis: Interpretation of double mutations Enzyme and Microbial Technology. 38: 795-802. DOI: 10.1016/j.enzmictec.2005.08.023  0.358
2006 Caligiuri A, D'Arrigo P, Rosini E, Tessaro D, Molla G, Servi S, Pollegioni L. Enzymatic conversion of unnatural amino acids by yeast D-amino acid oxidase Advanced Synthesis and Catalysis. 348: 2183-2190. DOI: 10.1002/Adsc.200606188  0.49
2006 Caligiuri A, D'Arrigo P, Rosini E, Tessaro D, Molla G, Servi S, Pollegioni L. Enzymatic conversion of unnatural amino acids by yeast D-amino acid oxidase Advanced Synthesis and Catalysis. 348: 2183-2190. DOI: 10.1002/adsc.200606188  0.385
2005 Pollegioni L, Lorenzi S, Rosini E, Marcone GL, Molla G, Verga R, Cabri W, Pilone MS. Evolution of an acylase active on cephalosporin C. Protein Science : a Publication of the Protein Society. 14: 3064-76. PMID 16260759 DOI: 10.1110/Ps.051671705  0.436
2005 Caldinelli L, Iametti S, Barbiroli A, Bonomi F, Fessas D, Molla G, Pilone MS, Pollegioni L. Dissecting the structural determinants of the stability of cholesterol oxidase containing covalently bound flavin. The Journal of Biological Chemistry. 280: 22572-81. PMID 15817448 DOI: 10.1074/Jbc.M500549200  0.31
2005 Mothet JP, Pollegioni L, Ouanounou G, Martineau M, Fossier P, Baux G. Glutamate receptor activation triggers a calcium-dependent and SNARE protein-dependent release of the gliotransmitter D-serine. Proceedings of the National Academy of Sciences of the United States of America. 102: 5606-11. PMID 15800046 DOI: 10.1073/Pnas.0408483102  0.702
2004 Boselli A, Piubelli L, Molla G, Sacchi S, Pilone MS, Ghisla S, Pollegioni L. On the mechanism of Rhodotorula gracilis D-amino acid oxidase: role of the active site serine 335. Biochimica Et Biophysica Acta. 1702: 19-32. PMID 15450847 DOI: 10.1016/J.Bbapap.2004.07.005  0.444
2004 Sacchi S, Rosini E, Molla G, Pilone MS, Pollegioni L. Modulating D-amino acid oxidase substrate specificity: production of an enzyme for analytical determination of all D-amino acids by directed evolution. Protein Engineering, Design & Selection : Peds. 17: 517-25. PMID 15310841 DOI: 10.1093/Protein/Gzh064  0.536
2004 Mörtl M, Diederichs K, Welte W, Molla G, Motteran L, Andriolo G, Pilone MS, Pollegioni L. Structure-function correlation in glycine oxidase from Bacillus subtilis. The Journal of Biological Chemistry. 279: 29718-27. PMID 15105420 DOI: 10.1074/Jbc.M401224200  0.396
2004 Caldinelli L, Iametti S, Barbiroli A, Bonomi F, Piubelli L, Ferranti P, Picariello G, Pilone MS, Pollegioni L. Unfolding intermediate in the peroxisomal flavoprotein D-amino acid oxidase. The Journal of Biological Chemistry. 279: 28426-34. PMID 15102841 DOI: 10.1074/Jbc.M403489200  0.419
2004 Pollegioni L, Caldinelli L, Molla G, Sacchi S, Pilone MS. Catalytic properties of D-amino acid oxidase in cephalosporin C bioconversion: a comparison between proteins from different sources. Biotechnology Progress. 20: 467-73. PMID 15058991 DOI: 10.1021/Bp034206Q  0.46
2003 Piubelli L, Molla G, Caldinelli L, Pilone MS, Pollegioni L. Dissection of the structural determinants involved in formation of the dimeric form of D-amino acid oxidase from Rhodotorula gracilis: role of the size of the betaF5-betaF6 loop. Protein Engineering. 16: 1063-9. PMID 14983088 DOI: 10.1093/Protein/Gzg125  0.417
2003 Molla G, Motteran L, Piubelli L, Pilone MS, Pollegioni L. Regulation of D-amino acid oxidase expression in the yeast Rhodotorula gracilis. Yeast (Chichester, England). 20: 1061-9. PMID 12961754 DOI: 10.1002/Yea.1023  0.502
2003 Pollegioni L, Iametti S, Fessas D, Caldinelli L, Piubelli L, Barbiroli A, Pilone MS, Bonomi F. Contribution of the dimeric state to the thermal stability of the flavoprotein D-amino acid oxidase. Protein Science : a Publication of the Protein Society. 12: 1018-29. PMID 12717024 DOI: 10.1110/Ps.0234603  0.317
2003 Molla G, Motteran L, Job V, Pilone MS, Pollegioni L. Kinetic mechanisms of glycine oxidase from Bacillus subtilis. European Journal of Biochemistry / Febs. 270: 1474-82. PMID 12654003 DOI: 10.1046/J.1432-1033.2003.03513.X  0.492
2002 Pollegioni L, Diederichs K, Molla G, Umhau S, Welte W, Ghisla S, Pilone MS. Yeast D-amino acid oxidase: structural basis of its catalytic properties. Journal of Molecular Biology. 324: 535-46. PMID 12445787 DOI: 10.1016/S0022-2836(02)01062-8  0.495
2002 Boselli A, Sacchi S, Job V, Pilone MS, Pollegioni L. Role of tyrosine 238 in the active site of Rhodotorula gracilis D-amino acid oxidase. A site-directed mutagenesis study. European Journal of Biochemistry / Febs. 269: 4762-71. PMID 12354107 DOI: 10.1046/J.1432-1033.2002.T01-1-03173.X  0.469
2002 Piubelli L, Caldinelli L, Molla G, Pilone MS, Pollegioni L. Conversion of the dimeric D-amino acid oxidase from Rhodotorula gracilis to a monomeric form. A rational mutagenesis approach. Febs Letters. 526: 43-8. PMID 12208501 DOI: 10.1016/S0014-5793(02)03111-3  0.49
2002 Sacchi S, Lorenzi S, Molla G, Pilone MS, Rossetti C, Pollegioni L. Engineering the substrate specificity of D-amino-acid oxidase. The Journal of Biological Chemistry. 277: 27510-6. PMID 12021281 DOI: 10.1074/Jbc.M203946200  0.532
2002 Job V, Molla G, Pilone MS, Pollegioni L. Overexpression of a recombinant wild-type and His-tagged Bacillus subtilis glycine oxidase in Escherichia coli. European Journal of Biochemistry / Febs. 269: 1456-63. PMID 11874460 DOI: 10.1046/J.1432-1033.2002.02790.X  0.436
2002 Vigetti D, Pollegioni L, Monetti C, Prati M, Bernardini G, Gornati R. Property comparison of recombinant amphibian and mammalian allantoicases. Febs Letters. 512: 323-8. PMID 11852104 DOI: 10.1016/S0014-5793(02)02264-0  0.388
2002 Job V, Marcone GL, Pilone MS, Pollegioni L. Glycine oxidase from Bacillus subtilis. Characterization of a new flavoprotein. The Journal of Biological Chemistry. 277: 6985-93. PMID 11744710 DOI: 10.1074/Jbc.M111095200  0.539
2002 Pilone MS, Pollegioni L. D-amino acid oxidase as an industrial biocatalyst Biocatalysis and Biotransformation. 20: 145-159. DOI: 10.1080/10242420290020679  0.463
2002 Boselli A, Sacchi S, Job V, Pilone MS, Pollegioni L. Role of tyrosine 238 in the active site of Rhodotorula gracilis D-amino acid oxidase: A site-directed mutagenesis study European Journal of Biochemistry. 269: 4762-4771. DOI: 10.1046/j.1432-1033.2002.t01-1-03173.x  0.354
2001 Pollegioni L, Harris CM, Molla G, Pilone MS, Ghisla S. Identification and role of ionizing functional groups at the active center of Rhodotorula gracilis D-amino acid oxidase. Febs Letters. 507: 323-6. PMID 11696364 DOI: 10.1016/S0014-5793(01)02983-0  0.448
2001 Harris CM, Pollegioni L, Ghisla S. pH and kinetic isotope effects in d-amino acid oxidase catalysis. European Journal of Biochemistry / Febs. 268: 5504-20. PMID 11683874 DOI: 10.1046/J.1432-1033.2001.02462.X  0.461
2001 Motteran L, Pilone MS, Molla G, Ghisla S, Pollegioni L. Cholesterol oxidase from Brevibacterium sterolicum. The relationship between covalent flavinylation and redox properties. The Journal of Biological Chemistry. 276: 18024-30. PMID 11359791 DOI: 10.1074/Jbc.M010953200  0.322
2000 Umhau S, Pollegioni L, Molla G, Diederichs K, Welte W, Pilone MS, Ghisla S. The x-ray structure of D-amino acid oxidase at very high resolution identifies the chemical mechanism of flavin-dependent substrate dehydrogenation. Proceedings of the National Academy of Sciences of the United States of America. 97: 12463-8. PMID 11070076 DOI: 10.1073/Pnas.97.23.12463  0.489
2000 Pollegioni L, Porrini D, Molla G, Pilone MS. Redox potentials and their pH dependence of D-amino-acid oxidase of Rhodotorula gracilis and Trigonopsis variabilis. European Journal of Biochemistry / Febs. 267: 6624-32. PMID 11054115 DOI: 10.1046/J.1432-1327.2000.01757.X  0.333
2000 Vigetti D, Monetti C, Pollegioni L, Taramelli R, Bernardini G. Xenopus allantoicase: molecular cloning, enzymatic activity and developmental expression. Archives of Biochemistry and Biophysics. 379: 90-6. PMID 10864446 DOI: 10.1006/Abbi.2000.1863  0.324
2000 Molla G, Porrini D, Job V, Motteran L, Vegezzi C, Campaner S, Pilone MS, Pollegioni L. Role of arginine 285 in the active site of Rhodotorula gracilis D-amino acid oxidase. A site-directed mutagenesis study. The Journal of Biological Chemistry. 275: 24715-21. PMID 10821840 DOI: 10.1074/Jbc.M908193199  0.464
1999 Harris CM, Molla G, Pilone MS, Pollegioni L. Studies on the reaction mechanism of Rhodotorula gracilis D-amino-acid oxidase. Role of the highly conserved Tyr-223 on substrate binding and catalysis. The Journal of Biological Chemistry. 274: 36233-40. PMID 10593911 DOI: 10.1074/Jbc.274.51.36233  0.507
1999 Pilone M, Molla G, Harris C, Porrini D, Vegezzi C, Campaner S, Pollegioni L. Site-directed mutagenesis in the active site of Rhodotorula gracilis D-amino acid oxidase Biochemical Society Transactions. 27: A38-A38. DOI: 10.1042/Bst027A038C  0.452
1998 Molla G, Vegezzi C, Pilone MS, Pollegioni L. Overexpression in Escherichia coil of a recombinant chimeric Rhodotorula gracilis D-amino acid oxidase Protein Expression and Purification. 14: 289-294. PMID 9790893 DOI: 10.1006/Prep.1998.0956  0.416
1998 Campaner S, Pollegioni L, Ross BD, Pilone MS. Limited proteolysis and site-directed mutagenesis reveal the origin of microheterogeneity in Rhodotorula gracilis D-amino acid oxidase Biochemical Journal. 330: 615-621. PMID 9480866 DOI: 10.1042/Bj3300615  0.446
1998 Stegman LD, Zheng H, Neal ER, Ben-Yoseph O, Pollegioni L, Pilone MS, Ross BD. Induction of cytotoxic oxidative stress by D-alanine in brain tumor cells expressing Rhodotorula gracilis D-amino acid oxidase: A cancer gene therapy strategy Human Gene Therapy. 9: 185-193. PMID 9472778 DOI: 10.1089/Hum.1998.9.2-185  0.487
1998 Sacchi S, Pollegioni L, Pilone MS, Rossetti C. Determination of D-amino acids using a D-amino acid oxidase biosensor with spectrophotometric and potentiometric detection Biotechnology Techniques. 12: 149-153. DOI: 10.1023/A:1008896602544  0.507
1997 Gadda G, Wels G, Pollegioni L, Zucchelli S, Ambrosius D, Pilone MS, Ghisla S. Characterization of cholesterol oxidase from Streptomyces hygroscopicus and Brevibacterium sterolicum European Journal of Biochemistry. 250: 369-376. PMID 9428686 DOI: 10.1111/J.1432-1033.1997.0369A.X  0.339
1997 Pollegioni L, Molla G, Campaner S, Martegani E, Pilone MS. Cloning, sequencing and expression in E. coli of a D-amino acid oxidase cDNA from Rhodotorula gracilis active on cephalosporin C Journal of Biotechnology. 58: 115-123. PMID 9383984 DOI: 10.1016/S0168-1656(97)00142-9  0.437
1997 Pollegioni L, Campaner S, Raibekas AA, Pilone MS. Identification of a reactive cysteine in the flavin-binding domain of Rhodotorula gracilis D-amino acid oxidase Archives of Biochemistry and Biophysics. 343: 1-5. PMID 9210639 DOI: 10.1006/Abbi.1997.0123  0.501
1997 Pollegioni L, Blodig W, Ghisla S. On the mechanism of D-amino acid oxidase: Structure/linear free energy correlations and deuterium kinetic isotope effects using substituted phenylglycines Journal of Biological Chemistry. 272: 4924-4934. PMID 9030552 DOI: 10.1074/Jbc.272.8.4924  0.309
1996 Pollegioni L, Pilone MS. On the holoenzyme reconstitution process in native and truncated Rhodotorula gracilis D-amino acid oxidase Archives of Biochemistry and Biophysics. 332: 58-62. PMID 8806709 DOI: 10.1006/Abbi.1996.0316  0.487
1996 Pollegioni L, Campaner S, Raibekasa AA, Pilone MS. Reactivity of sulfhydryl groups of Rliodotorula gracilis D-amino acid oxidase Biochemical Society Transactions. 24: 21S. PMID 8674666 DOI: 10.1042/Bst024021S  0.487
1995 Pollegioni L, Ceciliani F, Curti B, Ronchi S, Pilone MS. Studies on the structural and functional aspects of Rhodotorula gracilis D-amino acid oxidase by limited trypsinolysis Biochemical Journal. 310: 577-583. PMID 7654197 DOI: 10.1042/Bj3100577  0.451
1995 Pilone MS, Butò S, Pollegioni L. A process for bioconversion of cephalosporin C by Rhodotorula gracilis D-amino acid oxidase Biotechnology Letters. 17: 199-204. DOI: 10.1007/Bf00127988  0.404
1995 Faotto L, Pollegioni L, Ceciliani F, Ronchi S, Pilone MS. The primary structure of D-amino acid oxidase from Rhodotorula gracilis Biotechnology Letters. 17: 193-198. DOI: 10.1007/Bf00127987  0.506
1994 Pollegioni L, Fukui K, Massey V. Studies on the kinetic mechanism of pig kidney D-amino acid oxidase by site-directed mutagenesis of tyrosine 224 and tyrosine 228. The Journal of Biological Chemistry. 269: 31666-73. PMID 7989339  0.354
1994 Buto S, Pollegioni L, D'Angiuro L, Pilone MS. Evaluation of D-amino acid oxidase from Rhodotorula gracilis for the production of α-keto acids: A reactor system Biotechnology and Bioengineering. 44: 1288-1294. DOI: 10.1002/Bit.260441104  0.483
1993 Pollegioni L, Buto S, Tischer W, Ghisla S, Pilone MS. Characterization of D-amino acid oxidase from Trigonopsis variahilis Biochemistry and Molecular Biology International. 31: 709-717. PMID 7905327  0.329
1993 Pilone MS, Pollegioni L, Butò S. Stabilization of Yeast D-Amino Acid Oxidase by Matrix Covalent Attachment Studies in Organic Chemistry. 47: 415-420. DOI: 10.1016/B978-0-444-89372-7.50054-3  0.45
1992 Pollegioni L, Pilone MS. Purification of Rhodotorula gracilis d-amino acid oxidase Protein Expression and Purification. 3: 165-167. PMID 1358302 DOI: 10.1016/S1046-5928(05)80101-9  0.514
1992 Pollegioni L, Ghisla S, Pilone MS. Studies on the active centre of Rhodotorula gracilis D-amino acid oxidase and comparison with pig kidney enzyme Biochemical Journal. 286: 389-394. PMID 1356333 DOI: 10.1042/Bj2860389  0.518
1992 Pollegioni L, Falbo A, Pilone MS. Specificity and kinetics of Rhodotorula gracillis d-amino acid oxidase Biochimica Et Biophysica Acta (Bba)/Protein Structure and Molecular. 1120: 11-16. PMID 1348188 DOI: 10.1016/0167-4838(92)90418-D  0.542
1991 Perotti ME, Pollegioni L, Pilone MS. Expression of D-amino acid oxidase in Rhodotorula gracilis under induction conditions: A biochemical and cytochemical study European Journal of Cell Biology. 55: 104-113. PMID 1680680  0.432
1991 Casalin P, Pollegioni L, Curti B, Pilone Simonetta M. A study on apoenzyme from Rhodotorula gracilis D-amino acid oxidase European Journal of Biochemistry. 197: 513-517. PMID 1673927 DOI: 10.1111/J.1432-1033.1991.Tb15939.X  0.484
1991 Pollegioni L, Simonetta MP. Immunochemical studies on Rhodotorula gracilis D-amino acid oxidase. Experientia. 47: 232-5. PMID 1672654 DOI: 10.1007/Bf01958144  0.476
1991 Pollegioni L, Simonetta MP. Immunochemical studies on Rhodotorula gracilis D-amino acid oxidase Experientia. 47: 232-235. DOI: 10.1007/BF01958144  0.424
1989 Pilone Simonetta M, Casalin P, Pollegioni L, Ronchi S, Curti B. D-amino-acid oxidase from yeast Italian Journal of Biochemistry. 38: 296A-297A. PMID 2573585  0.424
1989 Pilone Simonetta M, Pollegioni L, Casalin P, Curti B, Ronchi S. Properties of D-amino-acid oxidase from Rhodotorula gracilis European Journal of Biochemistry. 180: 199-204. PMID 2565232 DOI: 10.1111/J.1432-1033.1989.Tb14634.X  0.526
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