| Year |
Citation |
Score |
| 2023 |
Venema WJ, Hiddingh S, van Loosdregt J, Bowes J, Balliu B, de Boer JH, Ossewaarde-van Norel J, Thompson SD, Langefeld CD, de Ligt A, van der Veken LT, Krijger PHL, de Laat W, Kuiper JJW. A cis-regulatory element regulates ERAP2 expression through autoimmune disease risk SNPs. Cell Genomics. 100460. PMID 38190099 DOI: 10.1016/j.xgen.2023.100460 |
0.314 |
|
| 2022 |
Rinzema NJ, Sofiadis K, Tjalsma SJD, Verstegen MJAM, Oz Y, Valdes-Quezada C, Felder AK, Filipovska T, van der Elst S, de Andrade Dos Ramos Z, Han R, Krijger PHL, de Laat W. Building regulatory landscapes reveals that an enhancer can recruit cohesin to create contact domains, engage CTCF sites and activate distant genes. Nature Structural & Molecular Biology. 29: 563-574. PMID 35710842 DOI: 10.1038/s41594-022-00787-7 |
0.445 |
|
| 2022 |
Bellefroid M, Rodari A, Galais M, Krijger PHL, Tjalsma SJD, Nestola L, Plant E, Vos ESM, Cristinelli S, Van Driessche B, Vanhulle C, Ait-Ammar A, Burny A, Ciuffi A, de Laat W, et al. Role of the cellular factor CTCF in the regulation of bovine leukemia virus latency and three-dimensional chromatin organization. Nucleic Acids Research. 50: 3190-3202. PMID 35234910 DOI: 10.1093/nar/gkac107 |
0.308 |
|
| 2021 |
Vos ESM, Valdes-Quezada C, Huang Y, Allahyar A, Verstegen MJAM, Felder AK, van der Vegt F, Uijttewaal ECH, Krijger PHL, de Laat W. Interplay between CTCF boundaries and a super enhancer controls cohesin extrusion trajectories and gene expression. Molecular Cell. PMID 34197738 DOI: 10.1016/j.molcel.2021.06.008 |
0.429 |
|
| 2020 |
Tjalsma SJ, de Laat W. Novel orthogonal methods to uncover the complexity and diversity of nuclear architecture. Current Opinion in Genetics & Development. 67: 10-17. PMID 33220512 DOI: 10.1016/j.gde.2020.10.002 |
0.329 |
|
| 2020 |
Hall AW, Chaffin M, Roselli C, Lin H, Lubitz SA, Bianchi V, Geeven G, Bedi K, Margulies KB, de Laat W, Tucker NR, Ellinor PT. Epigenetic Analyses of Human Left Atrial Tissue Identifies Gene Networks Underlying Atrial Fibrillation. Circulation. Genomic and Precision Medicine. PMID 33155827 DOI: 10.1161/CIRCGEN.120.003085 |
0.406 |
|
| 2020 |
Man JC, van Duijvenboden K, Krijger PH, Hooijkaas IB, van der Made I, de Gier-de Vries C, Wakker V, Creemers EE, de Laat W, Boukens BJ, Christoffels VM. Genetic Dissection of a Super Enhancer Controlling the Nppa-Nppb Cluster in the Heart. Circulation Research. PMID 33107387 DOI: 10.1161/CIRCRESAHA.120.317045 |
0.308 |
|
| 2020 |
Huang Y, Neijts R, de Laat W. How chromosome topologies get their shape: views from proximity ligation and microscopy methods. Febs Letters. PMID 33073863 DOI: 10.1002/1873-3468.13961 |
0.363 |
|
| 2020 |
van Ouwerkerk AF, Hall AW, Kadow ZA, Lazarevic S, Reyat JS, Tucker NR, Nadadur RD, Bosada FM, Bianchi V, Ellinor PT, Fabritz L, Martin JF, de Laat W, Kirchhof P, Moskowitz IP, et al. Epigenetic and Transcriptional Networks Underlying Atrial Fibrillation. Circulation Research. 127: 34-50. PMID 32717170 DOI: 10.1161/CIRCRESAHA.120.316574 |
0.35 |
|
| 2019 |
Krijger PHL, Geeven G, Bianchi V, Hilvering CRE, de Laat W. 4C-seq from start to end: a detailed protocol for sample preparation and data analysis. Methods (San Diego, Calif.). PMID 31351925 DOI: 10.1016/j.ymeth.2019.07.014 |
0.32 |
|
| 2019 |
Redolfi J, Zhan Y, Valdes-Quezada C, Kryzhanovska M, Guerreiro I, Iesmantavicius V, Pollex T, Grand RS, Mulugeta E, Kind J, Tiana G, Smallwood SA, de Laat W, Giorgetti L. DamC reveals principles of chromatin folding in vivo without crosslinking and ligation. Nature Structural & Molecular Biology. PMID 31133702 DOI: 10.1038/s41594-019-0231-0 |
0.335 |
|
| 2019 |
Laarman MD, Geeven G, Barnett P, Rinkel GJE, de Laat W, Ruigrok YM, Bakkers J. Chromatin Conformation Links Putative Enhancers in Intracranial Aneurysm-Associated Regions to Potential Candidate Genes. Journal of the American Heart Association. 8: e011201. PMID 30994044 DOI: 10.1161/Jaha.118.011201 |
0.467 |
|
| 2018 |
Allahyar A, Vermeulen C, Bouwman BAM, Krijger PHL, Verstegen MJAM, Geeven G, van Kranenburg M, Pieterse M, Straver R, Haarhuis JHI, Jalink K, Teunissen H, Renkens IJ, Kloosterman WP, Rowland BD, ... ... de Laat W, et al. Enhancer hubs and loop collisions identified from single-allele topologies. Nature Genetics. PMID 29988121 DOI: 10.1038/s41588-018-0161-5 |
0.708 |
|
| 2018 |
Geeven G, Teunissen H, de Laat W, de Wit E. peakC: a flexible, non-parametric peak calling package for 4C and Capture-C data. Nucleic Acids Research. PMID 29800273 DOI: 10.1093/nar/gky443 |
0.644 |
|
| 2017 |
Yang XH, Nadadur RD, Hilvering CR, Bianchi V, Werner M, Mazurek SR, Gadek M, Shen KM, Goldman JA, Tyan L, Bekeny J, Hall JM, Lee N, Perez-Cervantes C, Burnicka-Turek O, ... ... de Laat W, et al. Transcription-factor-dependent enhancer transcription defines a gene regulatory network for cardiac rhythm. Elife. 6. PMID 29280435 DOI: 10.7554/Elife.31683 |
0.383 |
|
| 2017 |
Vermeulen C, Geeven G, de Wit E, Verstegen MJAM, Jansen RPM, van Kranenburg M, de Bruijn E, Pulit SL, Kruisselbrink E, Shahsavari Z, Omrani D, Zeinali F, Najmabadi H, Katsila T, Vrettou C, ... ... de Laat W, et al. Sensitive Monogenic Noninvasive Prenatal Diagnosis by Targeted Haplotyping. American Journal of Human Genetics. PMID 28844486 DOI: 10.1016/j.ajhg.2017.07.012 |
0.589 |
|
| 2017 |
van de Werken HJ, de Haan JC, Feodorova Y, Bijos D, Weuts A, Theunis K, Holwerda S, Meuleman W, Pagie L, Thanisch K, Kumar P, Leonhardt H, Marynen P, van Steesel B, Voet T, ... de Laat W, et al. Small chromosomal regions position themselves autonomously according to their chromatin class. Genome Research. PMID 28341771 DOI: 10.1101/Gr.213751.116 |
0.418 |
|
| 2016 |
Krijger PH, de Laat W. Regulation of disease-associated gene expression in the 3D genome. Nature Reviews. Molecular Cell Biology. PMID 27826147 DOI: 10.1038/nrm.2016.138 |
0.359 |
|
| 2016 |
Neijts R, Amin S, van Rooijen C, Tan S, Creyghton MP, de Laat W, Deschamps J. Polarized regulatory landscape and Wnt responsiveness underlie Hox activation in embryos. Genes & Development. PMID 27633012 DOI: 10.1101/gad.285767.116 |
0.383 |
|
| 2016 |
Denker A, de Laat W. The second decade of 3C technologies: detailed insights into nuclear organization. Genes & Development. 30: 1357-82. PMID 27340173 DOI: 10.1101/gad.281964.116 |
0.348 |
|
| 2016 |
Wang X, Tucker NR, Rizki G, Mills R, Krijger PH, de Wit E, Subramanian V, Bartell E, Nguyen XX, Ye J, Leyton-Mange J, Dolmatova EV, van der Harst P, de Laat W, Ellinor PT, et al. Discovery and validation of sub-threshold genome-wide association study loci using epigenomic signatures. Elife. 5. PMID 27162171 DOI: 10.7554/Elife.10557 |
0.633 |
|
| 2016 |
Krijger PH, Di Stefano B, de Wit E, Limone F, van Oevelen C, de Laat W, Graf T. Cell-of-Origin-Specific 3D Genome Structure Acquired during Somatic Cell Reprogramming. Cell Stem Cell. PMID 26971819 DOI: 10.1016/j.stem.2016.01.007 |
0.657 |
|
| 2016 |
Wijchers PJ, Krijger PH, Geeven G, Zhu Y, Denker A, Verstegen MJ, Valdes-Quezada C, Vermeulen C, Janssen M, Teunissen H, Anink-Groenen LC, Verschure PJ, de Laat W. Cause and Consequence of Tethering a SubTAD to Different Nuclear Compartments. Molecular Cell. PMID 26833089 DOI: 10.1016/j.molcel.2016.01.001 |
0.373 |
|
| 2015 |
Austenaa LM, Barozzi I, Simonatto M, Masella S, Della Chiara G, Ghisletti S, Curina A, de Wit E, Bouwman BA, de Pretis S, Piccolo V, Termanini A, Prosperini E, Pelizzola M, de Laat W, et al. Transcription of Mammalian cis-Regulatory Elements Is Restrained by Actively Enforced Early Termination. Molecular Cell. 60: 460-74. PMID 26593720 DOI: 10.1016/j.molcel.2015.09.018 |
0.653 |
|
| 2015 |
Zepeda-Mendoza CJ, Mukhopadhyay S, Wong ES, Harder N, Splinter E, de Wit E, Eckersley-Maslin MA, Ried T, Eils R, Rohr K, Mills A, de Laat W, Flicek P, Sengupta AM, Spector DL. Quantitative analysis of chromatin interaction changes upon a 4.3 Mb deletion at mouse 4E2. Bmc Genomics. 16: 982. PMID 26589460 DOI: 10.1186/S12864-015-2137-5 |
0.716 |
|
| 2015 |
de Wit E, Vos ES, Holwerda SJ, Valdes-Quezada C, Verstegen MJ, Teunissen H, Splinter E, Wijchers PJ, Krijger PH, de Laat W. CTCF Binding Polarity Determines Chromatin Looping. Molecular Cell. PMID 26527277 DOI: 10.1016/j.molcel.2015.09.023 |
0.642 |
|
| 2015 |
Galli GG, Carrara M, Yuan WC, Valdes-Quezada C, Gurung B, Pepe-Mooney B, Zhang T, Geeven G, Gray NS, de Laat W, Calogero RA, Camargo FD. YAP Drives Growth by Controlling Transcriptional Pause Release from Dynamic Enhancers. Molecular Cell. PMID 26439301 DOI: 10.1016/j.molcel.2015.09.001 |
0.301 |
|
| 2015 |
Ramírez F, Lingg T, Toscano S, Lam KC, Georgiev P, Chung HR, Lajoie BR, de Wit E, Zhan Y, de Laat W, Dekker J, Manke T, Akhtar A. High-Affinity Sites Form an Interaction Network to Facilitate Spreading of the MSL Complex across the X Chromosome in Drosophila. Molecular Cell. 60: 146-62. PMID 26431028 DOI: 10.1016/J.Molcel.2015.08.024 |
0.663 |
|
| 2015 |
Denker A, de Laat W. A Long-Distance Chromatin Affair. Cell. 162: 942-3. PMID 26317462 DOI: 10.1016/j.cell.2015.08.022 |
0.318 |
|
| 2015 |
Bouwman BA, de Laat W. Getting the genome in shape: the formation of loops, domains and compartments. Genome Biology. 16: 154. PMID 26257189 DOI: 10.1186/s13059-015-0730-1 |
0.341 |
|
| 2015 |
Wijchers PJ, Geeven G, Eyres M, Bergsma AJ, Janssen M, Verstegen M, Zhu Y, Schell Y, Vermeulen C, de Wit E, de Laat W. Characterization and dynamics of pericentromere-associated domains in mice. Genome Research. 25: 958-69. PMID 25883320 DOI: 10.1101/gr.186643.114 |
0.71 |
|
| 2014 |
de Vree PJ, de Wit E, Yilmaz M, van de Heijning M, Klous P, Verstegen MJ, Wan Y, Teunissen H, Krijger PH, Geeven G, Eijk PP, Sie D, Ylstra B, Hulsman LO, van Dooren MF, ... ... de Laat W, et al. Targeted sequencing by proximity ligation for comprehensive variant detection and local haplotyping. Nature Biotechnology. 32: 1019-25. PMID 25129690 DOI: 10.1038/nbt.2959 |
0.663 |
|
| 2014 |
van Weerd JH, Badi I, van den Boogaard M, Stefanovic S, van de Werken HJ, Gomez-Velazquez M, Badia-Careaga C, Manzanares M, de Laat W, Barnett P, Christoffels VM. A large permissive regulatory domain exclusively controls Tbx3 expression in the cardiac conduction system. Circulation Research. 115: 432-41. PMID 24963028 DOI: 10.1161/CIRCRESAHA.115.303591 |
0.321 |
|
| 2014 |
Gröschel S, Sanders MA, Hoogenboezem R, De Wit E, Bouwman BAM, Erpelinck C, Van Der Velden VHJ, Havermans M, Avellino R, Van Lom K, Rombouts EJ, Van Duin M, Döhner K, Beverloo HB, Bradner JE, ... ... De Laat W, et al. A single oncogenic enhancer rearrangement causes concomitant EVI1 and GATA2 deregulation in Leukemia Cell. 157: 369-381. PMID 24703711 DOI: 10.1016/j.cell.2014.02.019 |
0.698 |
|
| 2013 |
de Laat W, Duboule D. Topology of mammalian developmental enhancers and their regulatory landscapes. Nature. 502: 499-506. PMID 24153303 DOI: 10.1038/Nature12753 |
0.629 |
|
| 2013 |
Denholtz M, Bonora G, Chronis C, Splinter E, de Laat W, Ernst J, Pellegrini M, Plath K. Long-range chromatin contacts in embryonic stem cells reveal a role for pluripotency factors and polycomb proteins in genome organization. Cell Stem Cell. 13: 602-16. PMID 24035354 DOI: 10.1016/J.Stem.2013.08.013 |
0.38 |
|
| 2013 |
Medvedovic J, Ebert A, Tagoh H, Tamir IM, Schwickert TA, Novatchkova M, Sun Q, Huis In 't Veld PJ, Guo C, Yoon HS, Denizot Y, Holwerda SJ, de Laat W, Cogné M, Shi Y, et al. Flexible long-range loops in the VH gene region of the Igh locus facilitate the generation of a diverse antibody repertoire. Immunity. 39: 229-44. PMID 23973221 DOI: 10.1016/J.Immuni.2013.08.011 |
0.35 |
|
| 2013 |
De Wit E, Bouwman BAM, Zhu Y, Klous P, Splinter E, Verstegen MJAM, Krijger PHL, Festuccia N, Nora EP, Welling M, Heard E, Geijsen N, Poot RA, Chambers I, De Laat W. The pluripotent genome in three dimensions is shaped around pluripotency factors Nature. 501: 227-231. PMID 23883933 DOI: 10.1038/nature12420 |
0.667 |
|
| 2013 |
Kaaij LT, van de Wetering M, Fang F, Decato B, Molaro A, van de Werken HJ, van Es JH, Schuijers J, de Wit E, de Laat W, Hannon GJ, Clevers HC, Smith AD, Ketting RF. DNA methylation dynamics during intestinal stem cell differentiation reveals enhancers driving gene expression in the villus. Genome Biology. 14: R50. PMID 23714178 DOI: 10.1186/Gb-2013-14-5-R50 |
0.654 |
|
| 2013 |
Holwerda SJB, de Laat W. CTCF: the protein, the binding partners, the binding sites and their chromatin loops. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 368: 20120369. PMID 23650640 DOI: 10.1098/rstb.2012.0369 |
0.364 |
|
| 2013 |
Krijger PHL, De Laat W. Identical cells with different 3D genomes; cause and consequences? Current Opinion in Genetics and Development. 23: 191-196. PMID 23415810 DOI: 10.1016/j.gde.2012.12.010 |
0.385 |
|
| 2013 |
Eijkelenboom A, Mokry M, De Wit E, Smits LM, Polderman PE, Van Triest MH, Van Boxtel R, Schulze A, De Laat W, Cuppen E, Burgering BMT. Genome-wide analysis of FOXO3 mediated transcription regulation through RNA polymerase II profiling Molecular Systems Biology. 9. PMID 23340844 DOI: 10.1038/msb.2012.74 |
0.711 |
|
| 2013 |
Melo CA, Drost J, Wijchers PJ, van de Werken H, de Wit E, Oude Vrielink JA, Elkon R, Melo SA, Léveillé N, Kalluri R, de Laat W, Agami R. eRNAs are required for p53-dependent enhancer activity and gene transcription. Molecular Cell. 49: 524-35. PMID 23273978 DOI: 10.1016/j.molcel.2012.11.021 |
0.69 |
|
| 2012 |
de Laat W, Dekker J. 3C-based technologies to study the shape of the genome Methods. 58: 189-191. PMID 23199640 DOI: 10.1016/J.Ymeth.2012.11.005 |
0.413 |
|
| 2012 |
Holwerda S, de Laat W. Chromatin loops, gene positioning, and gene expression. Frontiers in Genetics. 3: 217. PMID 23087710 DOI: 10.3389/fgene.2012.00217 |
0.514 |
|
| 2012 |
Van De Werken HJG, Landan G, Holwerda SJB, Hoichman M, Klous P, Chachik R, Splinter E, Valdes-Quezada C, Öz Y, Bouwman BAM, Verstegen MJAM, De Wit E, Tanay A, De Laat W. Robust 4C-seq data analysis to screen for regulatory DNA interactions Nature Methods. 9: 969-972. PMID 22961246 DOI: 10.1038/nmeth.2173 |
0.713 |
|
| 2012 |
Van De Werken HJG, De Vree PJP, Splinter E, Holwerda SJB, Klous P, De Wit E, De Laat W. 4C technology: Protocols and data analysis Methods in Enzymology. 513: 89-112. PMID 22929766 DOI: 10.1016/B978-0-12-391938-0.00004-5 |
0.641 |
|
| 2012 |
Moindrot B, Audit B, Klous P, Baker A, Thermes C, De Laat W, Bouvet P, Mongelard F, Arneodo A. 3D chromatin conformation correlates with replication timing and is conserved in resting cells Nucleic Acids Research. 40: 9470-9481. PMID 22879376 DOI: 10.1093/Nar/Gks736 |
0.337 |
|
| 2012 |
Splinter E, de Wit E, van de Werken HJG, Klous P, de Laat W. Determining long-range chromatin interactions for selected genomic sites using 4C-seq technology: From fixation to computation Methods. 58: 221-230. PMID 22609568 DOI: 10.1016/j.ymeth.2012.04.009 |
0.636 |
|
| 2012 |
de Wit E, de Laat W. A decade of 3C technologies: Insights into nuclear organization Genes and Development. 26: 11-24. PMID 22215806 DOI: 10.1101/gad.179804.111 |
0.668 |
|
| 2012 |
Holwerda S, de Laat W. Chromatin loops, gene positioning, and gene expression Frontiers in Genetics. 3. DOI: 10.3389/fgene.2012.00217 |
0.401 |
|
| 2011 |
Montavon T, Soshnikova N, Mascrez B, Joye E, Thevenet L, Splinter E, de Laat W, Spitz F, Duboule D. A regulatory archipelago controls Hox genes transcription in digits. Cell. 147: 1132-45. PMID 22118467 DOI: 10.1016/J.Cell.2011.10.023 |
0.653 |
|
| 2011 |
Noordermeer D, Leleu M, Splinter E, Rougemont J, De Laat W, Duboule D. The dynamic architecture of Hox gene clusters. Science (New York, N.Y.). 334: 222-5. PMID 21998387 DOI: 10.1126/Science.1207194 |
0.78 |
|
| 2011 |
Splinter E, De Laat W. The complex transcription regulatory landscape of our genome: Control in three dimensions Embo Journal. 30: 4345-4355. PMID 21952046 DOI: 10.1038/emboj.2011.344 |
0.354 |
|
| 2011 |
Noordermeer D, de Wit E, Klous P, van de Werken H, Simonis M, Lopez-Jones M, Eussen B, de Klein A, Singer RH, de Laat W. Variegated gene expression caused by cell-specific long-range DNA interactions. Nature Cell Biology. 13: 944-51. PMID 21706023 DOI: 10.1038/Ncb2278 |
0.809 |
|
| 2011 |
Splinter E, de Wit E, Nora EP, Klous P, van de Werken HJG, Zhu Y, Kaaij LJT, van Ijcken W, Gribnau J, Heard E, de Laat W. The inactive X chromosome adopts a unique three-dimensional conformation that is dependent on Xist RNA Genes and Development. 25: 1371-1383. PMID 21690198 DOI: 10.1101/gad.633311 |
0.693 |
|
| 2011 |
Tena JJ, Alonso ME, De La Calle-Mustienes E, Splinter E, De Laat W, Manzanares M, Gómez-Skarmeta JL. An evolutionarily conserved three-dimensional structure in the vertebrate Irx clusters facilitates enhancer sharing and coregulation Nature Communications. 2. PMID 21556064 DOI: 10.1038/ncomms1301 |
0.343 |
|
| 2011 |
Hakim O, Sung MH, Voss TC, Splinter E, John S, Sabo PJ, Thurman RE, Stamatoyannopoulos JA, de Laat W, Hager GL. Diverse gene reprogramming events occur in the same spatial clusters of distal regulatory elements. Genome Research. 21: 697-706. PMID 21471403 DOI: 10.1101/Gr.111153.110 |
0.509 |
|
| 2011 |
Tolhuis B, Blom M, Kerkhoven RM, Pagie L, Teunissen H, Nieuwland M, Simonis M, de Laat W, van Lohuizen M, van Steensel B. Interactions among polycomb domains are guided by chromosome architecture Plos Genetics. 7. PMID 21455484 DOI: 10.1371/journal.pgen.1001343 |
0.695 |
|
| 2011 |
Wijchers PJ, de Laat W. Genome organization influences partner selection for chromosomal rearrangements Trends in Genetics. 27: 63-71. PMID 21144612 DOI: 10.1016/j.tig.2010.11.001 |
0.316 |
|
| 2009 |
Simonis M, Klous P, Homminga I, Galjaard RJ, Rijkers EJ, Grosveld F, Meijerink JP, de Laat W. High-resolution identification of balanced and complex chromosomal rearrangements by 4C technology. Nature Methods. 6: 837-42. PMID 19820713 DOI: 10.1038/Nmeth.1391 |
0.628 |
|
| 2009 |
Louwers M, Splinter E, van Driel R, de Laat W, Stam M. Studying physical chromatin interactions in plants using Chromosome Conformation Capture (3C) Nature Protocols. 4: 1216-1229. PMID 19644461 DOI: 10.1038/nprot.2009.113 |
0.347 |
|
| 2009 |
Montavon T, Mascrez B, Spitz F, de Laat W, Duboule D. 22-P021 Long-range enhancer–promoter interactions in the HoxD complex Mechanisms of Development. 126: S335. DOI: 10.1016/J.Mod.2009.06.1232 |
0.662 |
|
| 2008 |
Noordermeer D, De Laat W. Joining the loops: β-globin gene regulation Iubmb Life. 60: 824-833. PMID 18767169 DOI: 10.1002/Iub.129 |
0.816 |
|
| 2008 |
Simonis M, de Laat W. FISH-eyed and genome-wide views on the spatial organisation of gene expression Biochimica Et Biophysica Acta - Molecular Cell Research. 1783: 2052-2060. PMID 18721832 DOI: 10.1016/j.bbamcr.2008.07.020 |
0.376 |
|
| 2008 |
Guelen L, Pagie L, Brasset E, Meuleman W, Faza MB, Talhout W, Eussen BH, De Klein A, Wessels L, De Laat W, Van Steensel B. Domain organization of human chromosomes revealed by mapping of nuclear lamina interactions Nature. 453: 948-951. PMID 18463634 DOI: 10.1038/Nature06947 |
0.355 |
|
| 2008 |
Noordermeer D, Branco MR, Splinter E, Klous P, Van Ijcken W, Swagemakers S, Koutsourakis M, Van Der Spek P, Pombo A, De Laat W. Transcription and chromatin organization of a housekeeping gene cluster containing an integrated β-globin locus control region Plos Genetics. 4. PMID 18369441 DOI: 10.1371/Journal.Pgen.1000016 |
0.824 |
|
| 2008 |
Palstra RJ, Simonis M, Klous P, Brasset E, Eijkelkamp B, de Laat W. Maintenance of long-range DNA interactions after inhibition of ongoing RNA polymerase II transcription. Plos One. 3: e1661. PMID 18286208 DOI: 10.1371/journal.pone.0001661 |
0.45 |
|
| 2008 |
de Laat W, Klous P, Kooren J, Noordermeer D, Palstra RJ, Simonis M, Splinter E, Grosveld F. Three-dimensional organization of gene expression in erythroid cells. Current Topics in Developmental Biology. 82: 117-39. PMID 18282519 DOI: 10.1016/S0070-2153(07)00005-1 |
0.806 |
|
| 2008 |
Palstra RJ, de Laat W, Grosveld F. Beta-globin regulation and long-range interactions. Advances in Genetics. 61: 107-42. PMID 18282504 DOI: 10.1016/S0065-2660(07)00004-1 |
0.659 |
|
| 2007 |
Simonis M, Kooren J, de Laat W. An evaluation of 3C-based methods to capture DNA interactions Nature Methods. 4: 895-901. PMID 17971780 DOI: 10.1038/nmeth1114 |
0.35 |
|
| 2007 |
de Laat W, Grosveld F. Inter-chromosomal gene regulation in the mammalian cell nucleus. Current Opinion in Genetics & Development. 17: 456-64. PMID 17884460 DOI: 10.1016/J.Gde.2007.07.009 |
0.695 |
|
| 2007 |
Hagège H, Klous P, Braem C, Splinter E, Dekker J, Cathala G, de Laat W, Forné T. Quantitative analysis of chromosome conformation capture assays (3C-qPCR). Nature Protocols. 2: 1722-1733. PMID 17641637 DOI: 10.1038/Nprot.2007.243 |
0.311 |
|
| 2007 |
de Laat W. Long-range DNA contacts: romance in the nucleus? Current Opinion in Cell Biology. 19: 317-320. PMID 17467258 DOI: 10.1016/j.ceb.2007.04.004 |
0.449 |
|
| 2007 |
Kooren J, Palstra RJ, Klous P, Splinter E, von Lindern M, Grosveld F, de Laat W. Beta-globin active chromatin Hub formation in differentiating erythroid cells and in p45 NF-E2 knock-out mice. The Journal of Biological Chemistry. 282: 16544-52. PMID 17428799 DOI: 10.1074/Jbc.M701159200 |
0.676 |
|
| 2006 |
Simonis M, Klous P, Splinter E, Moshkin Y, Willemsen R, De Wit E, Van Steensel B, De Laat W. Nuclear organization of active and inactive chromatin domains uncovered by chromosome conformation capture-on-chip (4C) Nature Genetics. 38: 1348-1354. PMID 17033623 DOI: 10.1038/ng1896 |
0.742 |
|
| 2006 |
Splinter E, Heath H, Kooren J, Palstra RJ, Klous P, Grosveld F, Galjart N, de Laat W. CTCF mediates long-range chromatin looping and local histone modification in the beta-globin locus. Genes & Development. 20: 2349-54. PMID 16951251 DOI: 10.1016/J.Bcmd.2006.10.131 |
0.674 |
|
| 2004 |
Drissen R, Palstra RJ, Gillemans N, Splinter E, Grosveld F, Philipsen S, de Laat W. The active spatial organization of the beta-globin locus requires the transcription factor EKLF. Genes & Development. 18: 2485-90. PMID 15489291 DOI: 10.1101/Gad.317004 |
0.674 |
|
| 2004 |
Patrinos GP, de Krom M, de Boer E, Langeveld A, Imam AM, Strouboulis J, de Laat W, Grosveld FG. Multiple interactions between regulatory regions are required to stabilize an active chromatin hub. Genes & Development. 18: 1495-509. PMID 15198986 DOI: 10.1101/gad.289704 |
0.696 |
|
| 2004 |
Splinter E, Grosveld F, de Laat W. 3C technology: analyzing the spatial organization of genomic loci in vivo. Methods in Enzymology. 375: 493-507. PMID 14870685 DOI: 10.1016/S0076-6879(03)75030-7 |
0.688 |
|
| 2003 |
Palstra RJ, Tolhuis B, Splinter E, Nijmeijer R, Grosveld F, de Laat W. The beta-globin nuclear compartment in development and erythroid differentiation. Nature Genetics. 35: 190-4. PMID 14517543 DOI: 10.1038/Ng1244 |
0.697 |
|
| 2003 |
de Laat W, Grosveld F. Spatial organization of gene expression: the active chromatin hub. Chromosome Research : An International Journal On the Molecular, Supramolecular and Evolutionary Aspects of Chromosome Biology. 11: 447-59. PMID 12971721 DOI: 10.1023/A:1024922626726 |
0.736 |
|
| 2002 |
Tolhuis B, Palstra RJ, Splinter E, Grosveld F, de Laat W. Looping and interaction between hypersensitive sites in the active beta-globin locus. Molecular Cell. 10: 1453-65. PMID 12504019 DOI: 10.1016/S1097-2765(02)00781-5 |
0.716 |
|
| Show low-probability matches. |