Kathrin Plath - Publications

Affiliations: 
University of California, Los Angeles, Los Angeles, CA 
Area:
X Chromosome inactivation
Website:
http://www.biolchem.ucla.edu/labs/plath/

108 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Dror I, Tan T, Plath K. A critical role for X-chromosome architecture in mammalian X-chromosome dosage compensation. Current Opinion in Genetics & Development. 87: 102235. PMID 39053028 DOI: 10.1016/j.gde.2024.102235  0.384
2024 Dror I, Chitiashvili T, Tan SYX, Cano CT, Sahakyan A, Markaki Y, Chronis C, Collier AJ, Deng W, Liang G, Sun Y, Afasizheva A, Miller J, Xiao W, Black DL, ... ... Plath K, et al. XIST directly regulates X-linked and autosomal genes in naive human pluripotent cells. Cell. 187: 110-129.e31. PMID 38181737 DOI: 10.1016/j.cell.2023.11.033  0.416
2023 Hoetker MS, Yagi M, Di Stefano B, Langerman J, Cristea S, Wong LP, Huebner AJ, Charlton J, Deng W, Haggerty C, Sadreyev RI, Meissner A, Michor F, Plath K, Hochedlinger K. H3K36 methylation maintains cell identity by regulating opposing lineage programmes. Nature Cell Biology. PMID 37460697 DOI: 10.1038/s41556-023-01191-z  0.383
2022 Jacobson EC, Pandya-Jones A, Plath K. A lifelong duty: how Xist maintains the inactive X chromosome. Current Opinion in Genetics & Development. 75: 101927. PMID 35717799 DOI: 10.1016/j.gde.2022.101927  0.409
2022 Chitiashvili T, Hsu FM, Dror I, Plath K, Clark A. FGFR3 is expressed by human primordial germ cells and is repressed after meiotic initiation to form primordial oocytes. Stem Cell Reports. PMID 35594860 DOI: 10.1016/j.stemcr.2022.04.015  0.307
2022 Collier AJ, Bendall A, Fabian C, Malcolm AA, Tilgner K, Semprich CI, Wojdyla K, Nisi PS, Kishore K, Roamio Franklin VN, Mirshekar-Syahkal B, D'Santos C, Plath K, Yusa K, Rugg-Gunn PJ. Genome-wide screening identifies Polycomb repressive complex 1.3 as an essential regulator of human naïve pluripotent cell reprogramming. Science Advances. 8: eabk0013. PMID 35333572 DOI: 10.1126/sciadv.abk0013  0.374
2021 Markaki Y, Gan Chong J, Wang Y, Jacobson EC, Luong C, Tan SYX, Jachowicz JW, Strehle M, Maestrini D, Banerjee AK, Mistry BA, Dror I, Dossin F, Schöneberg J, Heard E, ... ... Plath K, et al. Xist nucleates local protein gradients to propagate silencing across the X chromosome. Cell. PMID 34813726 DOI: 10.1016/j.cell.2021.10.022  0.364
2021 Deng W, Jacobson EC, Collier AJ, Plath K. The transcription factor code in iPSC reprogramming. Current Opinion in Genetics & Development. 70: 89-96. PMID 34246082 DOI: 10.1016/j.gde.2021.06.003  0.348
2021 Deng W, Jacobson EC, Collier AJ, Plath K. The transcription factor code in iPSC reprogramming. Current Opinion in Genetics & Development. 70: 89-96. PMID 34246082 DOI: 10.1016/j.gde.2021.06.003  0.348
2021 Guo J, Sosa E, Chitiashvili T, Nie X, Rojas EJ, Oliver E, Plath K, Hotaling JM, Stukenborg JB, Clark AT, Cairns BR. Single-cell analysis of the developing human testis reveals somatic niche cell specification and fetal germline stem cell establishment. Cell Stem Cell. PMID 33453151 DOI: 10.1016/j.stem.2020.12.004  0.314
2020 Meshorer E, Plath K. Chromatin and Nuclear Architecture in Stem Cells. Stem Cell Reports. 15: 1155-1157. PMID 33296671 DOI: 10.1016/j.stemcr.2020.11.012  0.333
2020 Chitiashvili T, Dror I, Kim R, Hsu FM, Chaudhari R, Pandolfi E, Chen D, Liebscher S, Schenke-Layland K, Plath K, Clark A. Female human primordial germ cells display X-chromosome dosage compensation despite the absence of X-inactivation. Nature Cell Biology. PMID 33257808 DOI: 10.1038/s41556-020-00607-4  0.393
2020 Pandya-Jones A, Markaki Y, Serizay J, Chitiashvili T, Mancia Leon WR, Damianov A, Chronis C, Papp B, Chen CK, McKee R, Wang XJ, Chau A, Sabri S, Leonhardt H, Zheng S, ... ... Plath K, et al. A protein assembly mediates Xist localization and gene silencing. Nature. PMID 32908311 DOI: 10.1038/S41586-020-2703-0  0.416
2020 Xi H, Langerman J, Sabri S, Chien P, Young CS, Younesi S, Hicks M, Gonzalez K, Fujiwara W, Marzi J, Liebscher S, Spencer M, Van Handel B, Evseenko D, Schenke-Layland K, ... Plath K, et al. A Human Skeletal Muscle Atlas Identifies the Trajectories of Stem and Progenitor Cells across Development and from Human Pluripotent Stem Cells. Cell Stem Cell. PMID 32396864 DOI: 10.1016/J.Stem.2020.04.017  0.393
2019 Takahashi R, Grzenda A, Allison T, Rawnsley J, Balin SJ, Sabri S, Plath K, Lowry WE. Defining transcriptional signatures of human hair follicle cell states. The Journal of Investigative Dermatology. PMID 31676413 DOI: 10.1016/J.Jid.2019.07.726  0.401
2019 Polioudakis D, de la Torre-Ubieta L, Langerman J, Elkins AG, Shi X, Stein JL, Vuong CK, Nichterwitz S, Gevorgian M, Opland CK, Lu D, Connell W, Ruzzo EK, Lowe JK, Hadzic T, ... ... Plath K, et al. A Single-Cell Transcriptomic Atlas of Human Neocortical Development during Mid-gestation. Neuron. PMID 31303374 DOI: 10.1016/J.Neuron.2019.06.011  0.42
2019 Bonora G, Rubbi L, Morselli M, Ma F, Chronis C, Plath K, Pellegrini M. DNA methylation estimation using methylation-sensitive restriction enzyme bisulfite sequencing (MREBS). Plos One. 14: e0214368. PMID 30946758 DOI: 10.1371/Journal.Pone.0214368  0.322
2019 Zhang W, Chronis C, Chen X, Zhang H, Spalinskas R, Pardo M, Chen L, Wu G, Zhu Z, Yu Y, Yu L, Choudhary J, Nichols J, Parast MM, Greber B, ... ... Plath K, et al. The BAF and PRC2 Complex Subunits Dpf2 and Eed Antagonistically Converge on Tbx3 to Control ESC Differentiation. Cell Stem Cell. 24: 138-152.e8. PMID 30609396 DOI: 10.1016/J.Stem.2018.12.001  0.388
2018 Fu K, Chronis C, Soufi A, Bonora G, Edwards M, Smale ST, Zaret KS, Plath K, Pellegrini M. Comparison of reprogramming factor targets reveals both species-specific and conserved mechanisms in early iPSC reprogramming. Bmc Genomics. 19: 956. PMID 30577748 DOI: 10.1186/S12864-018-5326-1  0.369
2018 Sun F, Chronis C, Kronenberg M, Chen XF, Su T, Lay FD, Plath K, Kurdistani SK, Carey MF. Promoter-Enhancer Communication Occurs Primarily within Insulated Neighborhoods. Molecular Cell. PMID 30527662 DOI: 10.1016/J.Molcel.2018.10.039  0.413
2018 Di Stefano B, Ueda M, Sabri S, Brumbaugh J, Huebner AJ, Sahakyan A, Clement K, Clowers KJ, Erickson AR, Shioda K, Gygi SP, Gu H, Shioda T, Meissner A, Takashima Y, ... Plath K, et al. Reduced MEK inhibition preserves genomic stability in naive human embryonic stem cells. Nature Methods. PMID 30127506 DOI: 10.1038/S41592-018-0104-1  0.478
2018 Jelinek D, Flores A, Uebelhoer M, Pasque V, Plath K, Iruela-Arispe ML, Christofk HR, Lowry WE, Coller HA. Mapping Metabolism: Monitoring Lactate Dehydrogenase Activity Directly in Tissue. Journal of Visualized Experiments : Jove. PMID 29985359 DOI: 10.3791/57760  0.318
2018 Sahakyan A, Yang Y, Plath K. The Role of Xist in X-Chromosome Dosage Compensation. Trends in Cell Biology. PMID 29910081 DOI: 10.1016/J.Tcb.2018.05.005  0.692
2018 Allison TF, Smith AJH, Anastassiadis K, Sloane-Stanley J, Biga V, Stavish D, Hackland J, Sabri S, Langerman J, Jones M, Plath K, Coca D, Barbaric I, Gokhale P, Andrews PW. Identification and Single-Cell Functional Characterization of an Endodermally Biased Pluripotent Substate in Human Embryonic Stem Cells. Stem Cell Reports. PMID 29779895 DOI: 10.1016/J.Stemcr.2018.04.015  0.439
2018 Pasque V, Karnik R, Chronis C, Petrella P, Langerman J, Bonora G, Song J, Vanheer L, Sadhu Dimashkie A, Meissner A, Plath K. X Chromosome Dosage Influences DNA Methylation Dynamics during Reprogramming to Mouse iPSCs. Stem Cell Reports. PMID 29681539 DOI: 10.1016/J.Stemcr.2018.03.019  0.509
2018 Keegan A, Plath K, Damoiseaux R. High-Throughput Screening of a Luciferase Reporter of Gene Silencing on the Inactive X Chromosome. Methods in Molecular Biology (Clifton, N.J.). 1755: 75-87. PMID 29671264 DOI: 10.1007/978-1-4939-7724-6_6  0.404
2018 Guo G, von Meyenn F, Rostovskaya M, Clarke J, Dietmann S, Baker D, Sahakyan A, Myers S, Bertone P, Reik W, Plath K, Smith A. Correction: Epigenetic resetting of human pluripotency (doi:10.1242/dev.146811). Development (Cambridge, England). 145. PMID 29669738 DOI: 10.1242/Dev.166397  0.527
2018 Sereti KI, Nguyen NB, Kamran P, Zhao P, Ranjbarvaziri S, Park S, Sabri S, Engel JL, Sung K, Kulkarni RP, Ding Y, Hsiai TK, Plath K, Ernst J, Sahoo D, et al. Analysis of cardiomyocyte clonal expansion during mouse heart development and injury. Nature Communications. 9: 754. PMID 29467410 DOI: 10.1038/S41467-018-02891-Z  0.328
2017 Sahakyan A, Plath K, Rougeulle C. Regulation of X-chromosome dosage compensation in human: mechanisms and model systems. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 372. PMID 28947660 DOI: 10.1098/Rstb.2016.0363  0.442
2017 Guo G, von Meyenn F, Rostovskaya M, Clarke J, Dietmann S, Baker D, Sahakyan A, Myers S, Bertone P, Reik W, Plath K, Smith A. Epigenetic resetting of human pluripotency. Development (Cambridge, England). 144: 2748-2763. PMID 28765214 DOI: 10.1242/Dev.146811  0.709
2017 Huang C, Su T, Xue Y, Cheng C, Lay FD, McKee RA, Li M, Vashisht A, Wohlschlegel J, Novitch BG, Plath K, Kurdistani SK, Carey M. Cbx3 maintains lineage specificity during neural differentiation. Genes & Development. 31: 241-246. PMID 28270516 DOI: 10.1101/Gad.292169.116  0.427
2017 Chronis C, Fiziev P, Papp B, Butz S, Bonora G, Sabri S, Ernst J, Plath K. Cooperative Binding of Transcription Factors Orchestrates Reprogramming. Cell. PMID 28111071 DOI: 10.1016/J.Cell.2016.12.016  0.4
2016 Sahakyan A, Kim R, Chronis C, Sabri S, Bonora G, Theunissen TW, Kuoy E, Langerman J, Clark AT, Jaenisch R, Plath K. Human Naive Pluripotent Stem Cells Model X Chromosome Dampening and X Inactivation. Cell Stem Cell. PMID 27989770 DOI: 10.1016/J.Stem.2016.10.006  0.698
2016 Patel S, Bonora G, Sahakyan A, Kim R, Chronis C, Langerman J, Fitz-Gibbon S, Rubbi L, Skelton RJ, Ardehali R, Pellegrini M, Lowry WE, Clark AT, Plath K. Human Embryonic Stem Cells Do Not Change Their X Inactivation Status during Differentiation. Cell Reports. PMID 27989715 DOI: 10.1016/J.Celrep.2016.11.054  0.677
2016 Gu W, Gaeta X, Sahakyan A, Chan AB, Hong CS, Kim R, Braas D, Plath K, Lowry WE, Christofk HR. Glycolytic Metabolism Plays a Functional Role in Regulating Human Pluripotent Stem Cell State. Cell Stem Cell. PMID 27618217 DOI: 10.1016/J.Stem.2016.08.008  0.41
2016 Pandya-Jones A, Plath K. The "lnc" between 3D Chromatin Structure and X Chromosome Inactivation. Seminars in Cell & Developmental Biology. PMID 27062886 DOI: 10.1016/J.Semcdb.2016.04.002  0.442
2016 Pastor WA, Chen D, Liu W, Kim R, Sahakyan A, Lukianchikov A, Plath K, Jacobsen SE, Clark AT. Naive Human Pluripotent Cells Feature a Methylation Landscape Devoid of Blastocyst or Germline Memory. Cell Stem Cell. 18: 323-329. PMID 26853856 DOI: 10.1016/J.Stem.2016.01.019  0.408
2015 Pasque V, Plath K. X chromosome reactivation in reprogramming and in development. Current Opinion in Cell Biology. 37: 75-83. PMID 26540406 DOI: 10.1016/J.Ceb.2015.10.006  0.52
2015 Minkovsky A, Sahakyan A, Bonora G, Damoiseaux R, Dimitrova E, Rubbi L, Pellegrini M, Radu CG, Plath K. A high-throughput screen of inactive X chromosome reactivation identifies the enhancement of DNA demethylation by 5-aza-2'-dC upon inhibition of ribonucleotide reductase. Epigenetics & Chromatin. 8: 42. PMID 26468331 DOI: 10.1186/S13072-015-0034-4  0.363
2015 McHugh CA, Chen CK, Chow A, Surka CF, Tran C, McDonel P, Pandya-Jones A, Blanco M, Burghard C, Moradian A, Sweredoski MJ, Shishkin AA, Su J, Lander ES, Hess S, ... Plath K, et al. The Xist lncRNA interacts directly with SHARP to silence transcription through HDAC3. Nature. 521: 232-6. PMID 25915022 DOI: 10.1038/Nature14443  0.49
2014 Pasque V, Tchieu J, Karnik R, Uyeda M, Sadhu Dimashkie A, Case D, Papp B, Bonora G, Patel S, Ho R, Schmidt R, McKee R, Sado T, Tada T, Meissner A, ... Plath K, et al. X chromosome reactivation dynamics reveal stages of reprogramming to pluripotency. Cell. 159: 1681-97. PMID 25525883 DOI: 10.1016/J.Cell.2014.11.040  0.832
2014 Minkovsky A, Sahakyan A, Rankin-Gee E, Bonora G, Patel S, Plath K. The Mbd1-Atf7ip-Setdb1 pathway contributes to the maintenance of X chromosome inactivation. Epigenetics & Chromatin. 7: 12. PMID 25028596 DOI: 10.1186/1756-8935-7-12  0.699
2014 Bonora G, Plath K, Denholtz M. A mechanistic link between gene regulation and genome architecture in mammalian development. Current Opinion in Genetics & Development. 27: 92-101. PMID 24998386 DOI: 10.1016/J.Gde.2014.05.002  0.795
2013 Denholtz M, Bonora G, Chronis C, Splinter E, de Laat W, Ernst J, Pellegrini M, Plath K. Long-range chromatin contacts in embryonic stem cells reveal a role for pluripotency factors and polycomb proteins in genome organization. Cell Stem Cell. 13: 602-16. PMID 24035354 DOI: 10.1016/J.Stem.2013.08.013  0.799
2013 Britton LM, Newhart A, Bhanu NV, Sridharan R, Gonzales-Cope M, Plath K, Janicki SM, Garcia BA. Initial characterization of histone H3 serine 10 O-acetylation. Epigenetics : Official Journal of the Dna Methylation Society. 8: 1101-13. PMID 23949383 DOI: 10.4161/Epi.26025  0.408
2013 Trounson A, Daley GQ, Pasque V, Plath K. A new route to human embryonic stem cells. Nature Medicine. 19: 820-1. PMID 23836223 DOI: 10.1038/Nm.3266  0.394
2013 Engreitz JM, Pandya-Jones A, McDonel P, Shishkin A, Sirokman K, Surka C, Kadri S, Xing J, Goren A, Lander ES, Plath K, Guttman M. The Xist lncRNA exploits three-dimensional genome architecture to spread across the X chromosome. Science (New York, N.Y.). 341: 1237973. PMID 23828888 DOI: 10.1126/Science.1237973  0.46
2013 Ho R, Papp B, Hoffman JA, Merrill BJ, Plath K. Stage-specific regulation of reprogramming to induced pluripotent stem cells by Wnt signaling and T cell factor proteins. Cell Reports. 3: 2113-26. PMID 23791530 DOI: 10.1016/J.Celrep.2013.05.015  0.395
2013 Sridharan R, Gonzales-Cope M, Chronis C, Bonora G, McKee R, Huang C, Patel S, Lopez D, Mishra N, Pellegrini M, Carey M, Garcia BA, Plath K. Proteomic and genomic approaches reveal critical functions of H3K9 methylation and heterochromatin protein-1γ in reprogramming to pluripotency. Nature Cell Biology. 15: 872-82. PMID 23748610 DOI: 10.1038/Ncb2768  0.681
2013 Minkovsky A, Barakat TS, Sellami N, Chin MH, Gunhanlar N, Gribnau J, Plath K. The pluripotency factor-bound intron 1 of Xist is dispensable for X chromosome inactivation and reactivation in vitro and in vivo. Cell Reports. 3: 905-18. PMID 23523354 DOI: 10.1016/J.Celrep.2013.02.018  0.737
2013 Papp B, Plath K. Epigenetics of reprogramming to induced pluripotency. Cell. 152: 1324-43. PMID 23498940 DOI: 10.1016/J.Cell.2013.02.043  0.507
2012 Denholtz M, Plath K. Pluripotency in 3D: genome organization in pluripotent cells. Current Opinion in Cell Biology. 24: 793-801. PMID 23199754 DOI: 10.1016/J.Ceb.2012.11.001  0.785
2012 Karumbayaram S, Lee P, Azghadi SF, Cooper AR, Patterson M, Kohn DB, Pyle A, Clark A, Byrne J, Zack JA, Plath K, Lowry WE. From skin biopsy to neurons through a pluripotent intermediate under Good Manufacturing Practice protocols. Stem Cells Translational Medicine. 1: 36-43. PMID 23197638 DOI: 10.5966/Sctm.2011-0001  0.347
2012 Chen XF, Lehmann L, Lin JJ, Vashisht A, Schmidt R, Ferrari R, Huang C, McKee R, Mosley A, Plath K, Kurdistani SK, Wohlschlegel J, Carey M. Mediator and SAGA have distinct roles in Pol II preinitiation complex assembly and function. Cell Reports. 2: 1061-7. PMID 23177621 DOI: 10.1016/J.Celrep.2012.10.019  0.62
2012 Plath K, Srivastava D, Alvarez-Buylla A, Tanaka EM, Kriegstein AR. Stem cells in the land of the rising sun: ISSCR 2012. Cell Stem Cell. 11: 607-14. PMID 23122288 DOI: 10.1016/J.Stem.2012.10.003  0.368
2012 Schmidt R, Plath K. The roles of the reprogramming factors Oct4, Sox2 and Klf4 in resetting the somatic cell epigenome during induced pluripotent stem cell generation. Genome Biology. 13: 251. PMID 23088445 DOI: 10.1186/Gb-2012-13-10-251  0.618
2012 Papp B, Plath K. Pluripotency re-centered around Esrrb. The Embo Journal. 31: 4255-7. PMID 23064149 DOI: 10.1038/Emboj.2012.285  0.362
2012 Nsair A, Schenke-Layland K, Van Handel B, Evseenko D, Kahn M, Zhao P, Mendelis J, Heydarkhan S, Awaji O, Vottler M, Geist S, Chyu J, Gago-Lopez N, Crooks GM, Plath K, et al. Characterization and therapeutic potential of induced pluripotent stem cell-derived cardiovascular progenitor cells. Plos One. 7: e45603. PMID 23056209 DOI: 10.1371/Journal.Pone.0045603  0.4
2012 Diaz Perez SV, Kim R, Li Z, Marquez VE, Patel S, Plath K, Clark AT. Derivation of new human embryonic stem cell lines reveals rapid epigenetic progression in vitro that can be prevented by chemical modification of chromatin. Human Molecular Genetics. 21: 751-64. PMID 22058289 DOI: 10.1093/Hmg/Ddr506  0.644
2012 Minkovsky A, Patel S, Plath K. Concise review: Pluripotency and the transcriptional inactivation of the female Mammalian X chromosome. Stem Cells (Dayton, Ohio). 30: 48-54. PMID 21997775 DOI: 10.1002/Stem.755  0.689
2011 Lin JJ, Lehmann LW, Bonora G, Sridharan R, Vashisht AA, Tran N, Plath K, Wohlschlegel JA, Carey M. Mediator coordinates PIC assembly with recruitment of CHD1. Genes & Development. 25: 2198-209. PMID 21979373 DOI: 10.1101/Gad.17554711  0.459
2011 Cooper AR, Patel S, Senadheera S, Plath K, Kohn DB, Hollis RP. Highly efficient large-scale lentiviral vector concentration by tandem tangential flow filtration. Journal of Virological Methods. 177: 1-9. PMID 21784103 DOI: 10.1016/J.Jviromet.2011.06.019  0.52
2011 Sridharan R, Plath K. Small RNAs loom large during reprogramming. Cell Stem Cell. 8: 599-601. PMID 21624799 DOI: 10.1016/J.Stem.2011.05.009  0.373
2011 Plath K, Lowry WE. Progress in understanding reprogramming to the induced pluripotent state. Nature Reviews. Genetics. 12: 253-65. PMID 21415849 DOI: 10.1038/Nrg2955  0.441
2011 Papp B, Plath K. Reprogramming to pluripotency: stepwise resetting of the epigenetic landscape. Cell Research. 21: 486-501. PMID 21321600 DOI: 10.1038/Cr.2011.28  0.468
2011 Ho R, Chronis C, Plath K. Mechanistic insights into reprogramming to induced pluripotency. Journal of Cellular Physiology. 226: 868-78. PMID 20945378 DOI: 10.1002/Jcp.22450  0.441
2010 Mayshar Y, Ben-David U, Lavon N, Biancotti JC, Yakir B, Clark AT, Plath K, Lowry WE, Benvenisty N. Identification and classification of chromosomal aberrations in human induced pluripotent stem cells. Cell Stem Cell. 7: 521-31. PMID 20887957 DOI: 10.1016/J.Stem.2010.07.017  0.473
2010 Mason MJ, Plath K, Zhou Q. Identification of context-dependent motifs by contrasting ChIP binding data. Bioinformatics (Oxford, England). 26: 2826-32. PMID 20870645 DOI: 10.1093/Bioinformatics/Btq546  0.367
2010 Tchieu J, Kuoy E, Chin MH, Trinh H, Patterson M, Sherman SP, Aimiuwu O, Lindgren A, Hakimian S, Zack JA, Clark AT, Pyle AD, Lowry WE, Plath K. Female human iPSCs retain an inactive X chromosome. Cell Stem Cell. 7: 329-42. PMID 20727844 DOI: 10.1016/J.Stem.2010.06.024  0.764
2010 Chin MH, Pellegrini M, Plath K, Lowry WE. Molecular analyses of human induced pluripotent stem cells and embryonic stem cells. Cell Stem Cell. 7: 263-9. PMID 20682452 DOI: 10.1016/J.Stem.2010.06.019  0.331
2010 Hiratani I, Ryba T, Itoh M, Rathjen J, Kulik M, Papp B, Fussner E, Bazett-Jones DP, Plath K, Dalton S, Rathjen PD, Gilbert DM. Genome-wide dynamics of replication timing revealed by in vitro models of mouse embryogenesis. Genome Research. 20: 155-69. PMID 19952138 DOI: 10.1101/Gr.099796.109  0.49
2009 Xu J, Watts JA, Pope SD, Gadue P, Kamps M, Plath K, Zaret KS, Smale ST. Transcriptional competence and the active marking of tissue-specific enhancers by defined transcription factors in embryonic and induced pluripotent stem cells. Genes & Development. 23: 2824-38. PMID 20008934 DOI: 10.1101/Gad.1861209  0.504
2009 Mason MJ, Fan G, Plath K, Zhou Q, Horvath S. Signed weighted gene co-expression network analysis of transcriptional regulation in murine embryonic stem cells. Bmc Genomics. 10: 327. PMID 19619308 DOI: 10.1186/1471-2164-10-327  0.603
2009 Gaspar-Maia A, Alajem A, Polesso F, Sridharan R, Mason MJ, Heidersbach A, Ramalho-Santos J, McManus MT, Plath K, Meshorer E, Ramalho-Santos M. Chd1 regulates open chromatin and pluripotency of embryonic stem cells. Nature. 460: 863-8. PMID 19587682 DOI: 10.1038/Nature08212  0.486
2009 Chin MH, Mason MJ, Xie W, Volinia S, Singer M, Peterson C, Ambartsumyan G, Aimiuwu O, Richter L, Zhang J, Khvorostov I, Ott V, Grunstein M, Lavon N, Benvenisty N, ... ... Plath K, et al. Induced pluripotent stem cells and embryonic stem cells are distinguished by gene expression signatures. Cell Stem Cell. 5: 111-23. PMID 19570518 DOI: 10.1016/J.Stem.2009.06.008  0.429
2009 Karumbayaram S, Novitch BG, Patterson M, Umbach JA, Richter L, Lindgren A, Conway AE, Clark AT, Goldman SA, Plath K, Wiedau-Pazos M, Kornblum HI, Lowry WE. Directed differentiation of human-induced pluripotent stem cells generates active motor neurons. Stem Cells (Dayton, Ohio). 27: 806-11. PMID 19350680 DOI: 10.1002/Stem.31  0.303
2009 Park TS, Galic Z, Conway AE, Lindgren A, van Handel BJ, Magnusson M, Richter L, Teitell MA, Mikkola HK, Lowry WE, Plath K, Clark AT. Derivation of primordial germ cells from human embryonic and induced pluripotent stem cells is significantly improved by coculture with human fetal gonadal cells. Stem Cells (Dayton, Ohio). 27: 783-95. PMID 19350678 DOI: 10.1002/Stem.13  0.449
2009 Daley GQ, Lensch MW, Jaenisch R, Meissner A, Plath K, Yamanaka S. Broader implications of defining standards for the pluripotency of iPSCs. Cell Stem Cell. 4: 200-1; author reply . PMID 19265657 DOI: 10.1016/J.Stem.2009.02.009  0.651
2009 Xie W, Song C, Young NL, Sperling AS, Xu F, Sridharan R, Conway AE, Garcia BA, Plath K, Clark AT, Grunstein M. Histone h3 lysine 56 acetylation is linked to the core transcriptional network in human embryonic stem cells. Molecular Cell. 33: 417-27. PMID 19250903 DOI: 10.1016/J.Molcel.2009.02.004  0.517
2009 Saxe JP, Tomilin A, Schöler HR, Plath K, Huang J. Post-translational regulation of Oct4 transcriptional activity. Plos One. 4: e4467. PMID 19221599 DOI: 10.1371/Journal.Pone.0004467  0.432
2009 Hochedlinger K, Plath K. Epigenetic reprogramming and induced pluripotency. Development (Cambridge, England). 136: 509-23. PMID 19168672 DOI: 10.1242/Dev.020867  0.446
2009 Sridharan R, Tchieu J, Mason MJ, Yachechko R, Kuoy E, Horvath S, Zhou Q, Plath K. Role of the murine reprogramming factors in the induction of pluripotency. Cell. 136: 364-77. PMID 19167336 DOI: 10.1016/J.Cell.2009.01.001  0.738
2009 Kanellopoulou C, Muljo SA, Dimitrov SD, Chen X, Colin C, Plath K, Livingston DM. X chromosome inactivation in the absence of Dicer. Proceedings of the National Academy of Sciences of the United States of America. 106: 1122-7. PMID 19164542 DOI: 10.1073/Pnas.0812210106  0.405
2009 Plath K, Sridharan R, Tchieu J, Mason MJ, Chin M, Yachechko R, Kuoy E, Zhou Q, Lowry B. Defining the Mechanism of Transcription Factor-Induced Epigenetic Reprogramming. Blood. 114: SCI-41-SCI-41. DOI: 10.1182/Blood.V114.22.Sci-41.Sci-41  0.741
2008 Lowry WE, Plath K. The many ways to make an iPS cell. Nature Biotechnology. 26: 1246-8. PMID 18997764 DOI: 10.1038/Nbt1108-1246  0.363
2008 Schenke-Layland K, Rhodes KE, Angelis E, Butylkova Y, Heydarkhan-Hagvall S, Gekas C, Zhang R, Goldhaber JI, Mikkola HK, Plath K, MacLellan WR. Reprogrammed mouse fibroblasts differentiate into cells of the cardiovascular and hematopoietic lineages. Stem Cells (Dayton, Ohio). 26: 1537-46. PMID 18450826 DOI: 10.1634/Stemcells.2008-0033  0.421
2008 Sridharan R, Plath K. Illuminating the black box of reprogramming. Cell Stem Cell. 2: 295-7. PMID 18397745 DOI: 10.1016/J.Stem.2008.03.015  0.384
2008 Lowry WE, Richter L, Yachechko R, Pyle AD, Tchieu J, Sridharan R, Clark AT, Plath K. Generation of human induced pluripotent stem cells from dermal fibroblasts. Proceedings of the National Academy of Sciences of the United States of America. 105: 2883-8. PMID 18287077 DOI: 10.1073/Pnas.0711983105  0.737
2007 Maherali N, Sridharan R, Xie W, Utikal J, Eminli S, Arnold K, Stadtfeld M, Yachechko R, Tchieu J, Jaenisch R, Plath K, Hochedlinger K. Directly reprogrammed fibroblasts show global epigenetic remodeling and widespread tissue contribution. Cell Stem Cell. 1: 55-70. PMID 18371336 DOI: 10.1016/J.Stem.2007.05.014  0.822
2007 Nusinow DA, Sharp JA, Morris A, Salas S, Plath K, Panning B. The histone domain of macroH2A1 contains several dispersed elements that are each sufficient to direct enrichment on the inactive X chromosome. Journal of Molecular Biology. 371: 11-8. PMID 17570398 DOI: 10.1016/J.Jmb.2007.05.063  0.811
2006 Bernstein BE, Mikkelsen TS, Xie X, Kamal M, Huebert DJ, Cuff J, Fry B, Meissner A, Wernig M, Plath K, Jaenisch R, Wagschal A, Feil R, Schreiber SL, Lander ES. A bivalent chromatin structure marks key developmental genes in embryonic stem cells. Cell. 125: 315-26. PMID 16630819 DOI: 10.1016/J.Cell.2006.02.041  0.774
2006 Boyer LA, Plath K, Zeitlinger J, Brambrink T, Medeiros LA, Lee TI, Levine SS, Wernig M, Tajonar A, Ray MK, Bell GW, Otte AP, Vidal M, Gifford DK, Young RA, et al. Polycomb complexes repress developmental regulators in murine embryonic stem cells. Nature. 441: 349-53. PMID 16625203 DOI: 10.1038/Nature04733  0.831
2006 Beard C, Hochedlinger K, Plath K, Wutz A, Jaenisch R. Efficient method to generate single-copy transgenic mice by site-specific integration in embryonic stem cells. Genesis (New York, N.Y. : 2000). 44: 23-8. PMID 16400644 DOI: 10.1002/Gene.20180  0.589
2006 Chu F, Nusinow DA, Chalkley RJ, Plath K, Panning B, Burlingame AL. Mapping post-translational modifications of the histone variant MacroH2A1 using tandem mass spectrometry. Molecular & Cellular Proteomics : McP. 5: 194-203. PMID 16210244 DOI: 10.1074/Mcp.M500285-Mcp200  0.785
2005 de la Cruz CC, Fang J, Plath K, Worringer KA, Nusinow DA, Zhang Y, Panning B. Developmental regulation of Suz 12 localization. Chromosoma. 114: 183-92. PMID 15986205 DOI: 10.1007/S00412-005-0008-6  0.805
2004 Plath K, Talbot D, Hamer KM, Otte AP, Yang TP, Jaenisch R, Panning B. Developmentally regulated alterations in Polycomb repressive complex 1 proteins on the inactive X chromosome. The Journal of Cell Biology. 167: 1025-35. PMID 15596546 DOI: 10.1083/Jcb.200409026  0.814
2004 Plath K, Wilkinson BM, Stirling CJ, Rapoport TA. Interactions between Sec complex and prepro-alpha-factor during posttranslational protein transport into the endoplasmic reticulum. Molecular Biology of the Cell. 15: 1-10. PMID 14617809 DOI: 10.1091/Mbc.E03-06-0390  0.517
2004 Chakravarthy S, Nusinow D, Plath K, Perche P, Khochbin S, Panning B, Luger K. MACRO-H2A: A STRUCTURALLY AND FUNCTIONALLY DIVERSE HISTONE VARIANT Cold Spring Harbor Symposia On Quantitative Biology. 69: 1-1. DOI: 10.1101/Sqb.2004.69.S46  0.769
2003 Plath K, Fang J, Mlynarczyk-Evans SK, Cao R, Worringer KA, Wang H, de la Cruz CC, Otte AP, Panning B, Zhang Y. Role of histone H3 lysine 27 methylation in X inactivation. Science (New York, N.Y.). 300: 131-5. PMID 12649488 DOI: 10.1126/Science.1084274  0.758
2002 Plath K, Mlynarczyk-Evans S, Nusinow DA, Panning B. Xist RNA and the mechanism of X chromosome inactivation. Annual Review of Genetics. 36: 233-78. PMID 12429693 DOI: 10.1146/Annurev.Genet.36.042902.092433  0.781
2000 Menetret JF, Neuhof A, Morgan DG, Plath K, Radermacher M, Rapoport TA, Akey CW. The structure of ribosome-channel complexes engaged in protein translocation. Molecular Cell. 6: 1219-32. PMID 11106759 DOI: 10.1016/S1097-2765(00)00118-0  0.494
2000 Plath K, Rapoport TA. Spontaneous release of cytosolic proteins from posttranslational substrates before their transport into the endoplasmic reticulum. The Journal of Cell Biology. 151: 167-78. PMID 11018062 DOI: 10.1083/Jcb.151.1.167  0.525
1999 Rapoport TA, Matlack KE, Plath K, Misselwitz B, Staeck O. Posttranslational protein translocation across the membrane of the endoplasmic reticulum. Biological Chemistry. 380: 1143-50. PMID 10595576 DOI: 10.1515/Bc.1999.145  0.512
1999 Matlack KE, Misselwitz B, Plath K, Rapoport TA. BiP acts as a molecular ratchet during posttranslational transport of prepro-alpha factor across the ER membrane. Cell. 97: 553-64. PMID 10367885 DOI: 10.1016/S0092-8674(00)80767-9  0.512
1998 Plath K, Mothes W, Wilkinson BM, Stirling CJ, Rapoport TA. Signal sequence recognition in posttranslational protein transport across the yeast ER membrane. Cell. 94: 795-807. PMID 9753326 DOI: 10.1016/S0092-8674(00)81738-9  0.642
1997 Matlack KE, Plath K, Misselwitz B, Rapoport TA. Protein transport by purified yeast Sec complex and Kar2p without membranes. Science (New York, N.Y.). 277: 938-41. PMID 9252322 DOI: 10.1126/Science.277.5328.938  0.515
1996 Hanein D, Matlack KE, Jungnickel B, Plath K, Kalies KU, Miller KR, Rapoport TA, Akey CW. Oligomeric rings of the Sec61p complex induced by ligands required for protein translocation. Cell. 87: 721-32. PMID 8929540 DOI: 10.1016/S0092-8674(00)81391-4  0.514
1996 Finke K, Plath K, Panzner S, Prehn S, Rapoport TA, Hartmann E, Sommer T. A second trimeric complex containing homologs of the Sec61p complex functions in protein transport across the ER membrane of S. cerevisiae. The Embo Journal. 15: 1482-94. PMID 8612571 DOI: 10.1002/J.1460-2075.1996.Tb00492.X  0.535
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