Year |
Citation |
Score |
2015 |
Evans GB, Cameron SA, Luxenburger A, Guan R, Suarez J, Thomas K, Schramm VL, Tyler PC. Tight binding enantiomers of pre-clinical drug candidates. Bioorganic & Medicinal Chemistry. 23: 5326-33. PMID 26260335 DOI: 10.1016/J.Bmc.2015.07.059 |
0.423 |
|
2015 |
Freitas EO, Nico D, Guan R, Meyer-Fernandes JR, Clinch K, Evans GB, Tyler PC, Schramm VL, Palatnik-de-Sousa CB. Immucillins Impair Leishmania (L.) infantum chagasi and Leishmania (L.) amazonensis Multiplication In Vitro. Plos One. 10: e0124183. PMID 25909893 DOI: 10.1371/Journal.Pone.0124183 |
0.325 |
|
2013 |
Guan R, Tyler PC, Evans GB, Schramm VL. Thermodynamic analysis of transition-state features in picomolar inhibitors of human 5'-methylthioadenosine phosphorylase. Biochemistry. 52: 8313-22. PMID 24148083 DOI: 10.1021/Bi401188W |
0.473 |
|
2012 |
Guan R, Ho MC, Fröhlich RF, Tyler PC, Almo SC, Schramm VL. Methylthioadenosine deaminase in an alternative quorum sensing pathway in Pseudomonas aeruginosa. Biochemistry. 51: 9094-103. PMID 23050701 DOI: 10.1021/Bi301062Y |
0.42 |
|
2012 |
Thomas K, Haapalainen AM, Burgos ES, Evans GB, Tyler PC, Gulab S, Guan R, Schramm VL. Femtomolar inhibitors bind to 5'-methylthioadenosine nucleosidases with favorable enthalpy and entropy. Biochemistry. 51: 7541-50. PMID 22931458 DOI: 10.1021/Bi3009938 |
0.442 |
|
2011 |
Guan R, Ho MC, Brenowitz M, Tyler PC, Evans GB, Almo SC, Schramm VL. Entropy-driven binding of picomolar transition state analogue inhibitors to human 5'-methylthioadenosine phosphorylase. Biochemistry. 50: 10408-17. PMID 21985704 DOI: 10.1021/Bi201321X |
0.473 |
|
2011 |
Magalhães ML, Czekster CM, Guan R, Malashkevich VN, Almo SC, Levy M. Evolved streptavidin mutants reveal key role of loop residue in high-affinity binding. Protein Science : a Publication of the Protein Society. 20: 1145-54. PMID 21520321 DOI: 10.1002/Pro.642 |
0.404 |
|
2011 |
Guan R, Ho MC, Almo SC, Schramm VL. Methylthioinosine phosphorylase from Pseudomonas aeruginosa. Structure and annotation of a novel enzyme in quorum sensing. Biochemistry. 50: 1247-54. PMID 21197954 DOI: 10.1021/Bi101642D |
0.479 |
|
2011 |
Salsi E, Guan R, Campanini B, Bettati S, Lin J, Cook PF, Mozzarelli A. Exploring O-acetylserine sulfhydrylase-B isoenzyme from Salmonella typhimurium by fluorescence spectroscopy. Archives of Biochemistry and Biophysics. 505: 178-85. PMID 20937239 DOI: 10.1016/J.Abb.2010.10.005 |
0.591 |
|
2010 |
Tian H, Guan R, Salsi E, Campanini B, Bettati S, Kumar VP, Karsten WE, Mozzarelli A, Cook PF. Identification of the structural determinants for the stability of substrate and aminoacrylate external Schiff bases in O-acetylserine sulfhydrylase-A. Biochemistry. 49: 6093-103. PMID 20550197 DOI: 10.1021/Bi100473V |
0.706 |
|
2009 |
Guan R, Nimmo SA, Schnackerz KD, Cook PF. (31)P NMR studies of O-acetylserine sulfhydrylase-B from Salmonella typhimurium. Archives of Biochemistry and Biophysics. 487: 85-90. PMID 19501038 DOI: 10.1016/J.Abb.2009.05.016 |
0.631 |
|
2008 |
Guan R, Roderick SL, Huang B, Cook PF. Roles of histidines 154 and 189 and aspartate 139 in the active site of serine acetyltransferase from Haemophilus influenzae. Biochemistry. 47: 6322-8. PMID 18498176 DOI: 10.1021/Bi800075C |
0.613 |
|
2008 |
Tai CH, Rabeh WM, Guan R, Schnackerz KD, Cook PF. Role of Histidine-152 in cofactor orientation in the PLP-dependent O-acetylserine sulfhydrylase reaction. Archives of Biochemistry and Biophysics. 472: 115-25. PMID 18275838 DOI: 10.1016/J.Abb.2008.01.021 |
0.665 |
|
2008 |
Tai CH, Rabeh WM, Guan R, Schnackerz KD, Cook PF. Effect of mutation of lysine-120, located at the entry to the active site of O-acetylserine sulfhydrylase-A from Salmonella typhimurium. Biochimica Et Biophysica Acta. 1784: 629-37. PMID 18243146 DOI: 10.1016/J.Bbapap.2007.12.017 |
0.658 |
|
2005 |
Zhang J, Guan R, Tan Z, Yu Y, Hou Z, Qi Z, Wang S. Purification and properties of lipases/esterases from a Bacillus strain for enantioselective resolution of (S)-Ketoprofen. Artificial Cells, Blood Substitutes, and Immobilization Biotechnology. 33: 435-45. PMID 16317962 DOI: 10.1080/10731190500290105 |
0.437 |
|
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