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Christoph Arenz - Publications

Affiliations: 
2004- Humboldt-Universität zu Berlin, Berlin, Germany 
Area:
Organic chemistry, bioorganic chemistry
Website:
https://www.chemie.hu-berlin.de/arenz/Arenzcv.htm
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40 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Lone MA, Hülsmeier AJ, M Saied E, Karsai G, Arenz C, von Eckardstein A, Hornemann T. Subunit composition of the mammalian serine-palmitoyltransferase defines the spectrum of straight and methyl-branched long-chain bases. Proceedings of the National Academy of Sciences of the United States of America. PMID 32576697 DOI: 10.1073/Pnas.2002391117  0.311
2020 Naser E, Kadow S, Schumacher F, Mohamed ZH, Kappe C, Hessler G, Pollmeier B, Kleuser B, Arenz C, Becker KA, Gulbins E, Carpinteiro A. Characterization of the small molecule ARC39, a direct and specific inhibitor of acid sphingomyelinase . Journal of Lipid Research. PMID 32156719 DOI: 10.1194/Jlr.Ra120000682  0.394
2020 Kappe C, Mohamed ZH, Naser E, Carpinteiro A, Arenz C. A novel visible range FRET probe for monitoring acid sphingomyelinase activity in living cells. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 32092185 DOI: 10.1002/Chem.202000133  0.326
2019 Waldmann H, Laraia L, Garivet G, Foley DJ, Kaiser N, Müller S, Zinken S, Pinkert T, Wilke J, Corkery D, Pahl A, Sievers S, Janning P, Arenz C, Wu Y, et al. Image-based morphological profiling identifies a lysosomotropic, iron-sequestering autophagy inhibitor. Angewandte Chemie (International Ed. in English). PMID 31769920 DOI: 10.1002/Anie.201913712  0.331
2019 Živanović V, Seifert S, Drescher D, Schrade P, Werner S, Guttmann P, Szekeres GP, Bachmann S, Schneider G, Arenz C, Kneipp J. Optical Nanosensing of Lipid Accumulation due to Enzyme Inhibition in Live Cells. Acs Nano. PMID 31314989 DOI: 10.1021/Acsnano.9B04001  0.326
2018 Mohamed ZH, Rhein C, Saied EM, Kornhuber J, Arenz C. FRET probes for measuring sphingolipid metabolizing enzyme activity. Chemistry and Physics of Lipids. 216: 152-161. PMID 30261173 DOI: 10.1016/J.Chemphyslip.2018.09.014  0.312
2018 Ren J, Saied EM, Zhong A, Snider J, Ruiz C, Arenz C, Obeid LM, Girnun GD, Hannun YA. Tsc3 regulates SPT amino acid choice in Saccharomyces cerevisiae by promoting alanine in sphingolipid pathway. Journal of Lipid Research. PMID 30154231 DOI: 10.1194/Jlr.M088195  0.325
2018 Saied EM, Le TL, Hornemann T, Arenz C. Synthesis and characterization of some atypical sphingoid bases. Bioorganic & Medicinal Chemistry. 26: 4047-4057. PMID 29960730 DOI: 10.1016/J.Bmc.2018.06.031  0.323
2017 Pinkert T, Furkert D, Korte T, Herrmann A, Arenz C. Amplification of a FRET Probe by Lipid-Water Partition for the Detection of Acid Sphingomyelinase in Live Cells. Angewandte Chemie (International Ed. in English). PMID 28156033 DOI: 10.1002/Anie.201611706  0.336
2017 Alecu I, Othman A, Penno A, Saied EM, Arenz C, von Eckardstein A, Hornemann T. Cytotoxic 1-deoxysphingolipids are metabolized by a cytochrome P450-dependent pathway. Journal of Lipid Research. 58: 60-71. PMID 27872144 DOI: 10.1194/Jlr.M072421  0.309
2016 Hesse M, Arenz C. A Rapid and Versatile Assay for Ago2-Mediated Cleavage by Using Branched Rolling Circle Amplification. Chembiochem : a European Journal of Chemical Biology. 17: 304-7. PMID 26677110 DOI: 10.1002/Cbic.201500537  0.334
2016 Saied EM, Arenz C. Inhibitors of Ceramidases. Chemistry and Physics of Lipids. 197: 60-8. PMID 26220616 DOI: 10.1016/J.Chemphyslip.2015.07.009  0.402
2014 Saied EM, Arenz C. Small molecule inhibitors of ceramidases. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 34: 197-212. PMID 24977492 DOI: 10.1159/000362995  0.358
2014 Saied EM, Diederich S, Arenz C. Facile synthesis of the CERT inhibitor HPA-12 and some novel derivatives Chemistry - An Asian Journal. 9: 2092-2094. PMID 24888419 DOI: 10.1002/Asia.201402241  0.337
2014 Schwarzmann G, Arenz C, Sandhoff K. Labeled chemical biology tools for investigating sphingolipid metabolism, trafficking and interaction with lipids and proteins. Biochimica Et Biophysica Acta. 1841: 1161-73. PMID 24389251 DOI: 10.1016/J.Bbalip.2013.12.011  0.613
2013 Petersen NH, Olsen OD, Groth-Pedersen L, Ellegaard AM, Bilgin M, Redmer S, Ostenfeld MS, Ulanet D, Dovmark TH, Lønborg A, Vindeløv SD, Hanahan D, Arenz C, Ejsing CS, Kirkegaard T, et al. Transformation-associated changes in sphingolipid metabolism sensitize cells to lysosomal cell death induced by inhibitors of acid sphingomyelinase. Cancer Cell. 24: 379-93. PMID 24029234 DOI: 10.1016/J.Ccr.2013.08.003  0.334
2013 Bhabak KP, Hauser A, Redmer S, Banhart S, Heuer D, Arenz C. Development of a novel FRET probe for the real-time determination of ceramidase activity. Chembiochem : a European Journal of Chemical Biology. 14: 1049-52. PMID 23728798 DOI: 10.1002/Cbic.201300207  0.664
2013 Bhabak KP, Arenz C. Novel drugs targeting sphingolipid metabolism. Handbook of Experimental Pharmacology. 187-96. PMID 23579456 DOI: 10.1007/978-3-7091-1368-4_10  0.658
2013 Bhabak KP, Kleuser B, Huwiler A, Arenz C. Effective inhibition of acid and neutral ceramidases by novel B-13 and LCL-464 analogues. Bioorganic & Medicinal Chemistry. 21: 874-82. PMID 23312611 DOI: 10.1016/J.Bmc.2012.12.014  0.693
2013 Bhabak KP, Hauser A, Redmer S, Banhart S, Heuer D, Arenz C. Cover Picture: Development of a Novel FRET Probe for the Real-Time Determination of Ceramidase Activity (ChemBioChem 9/2013) Chembiochem. 14: 1017-1017. DOI: 10.1002/Cbic.201390029  0.655
2012 Bhabak KP, Arenz C. Novel amide- and sulfonamide-based aromatic ethanolamines: effects of various substituents on the inhibition of acid and neutral ceramidases. Bioorganic & Medicinal Chemistry. 20: 6162-70. PMID 22989912 DOI: 10.1016/J.Bmc.2012.08.031  0.69
2012 Bhabak KP, Proksch D, Redmer S, Arenz C. Novel fluorescent ceramide derivatives for probing ceramidase substrate specificity. Bioorganic & Medicinal Chemistry. 20: 6154-61. PMID 22989909 DOI: 10.1016/J.Bmc.2012.08.035  0.676
2011 Proksch D, Klein JJ, Arenz C. Potent inhibition of Acid ceramidase by novel B-13 analogues. Journal of Lipids. 2011: 971618. PMID 21490813 DOI: 10.1155/2011/971618  0.361
2010 Arenz C. Small molecule inhibitors of acid sphingomyelinase. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 26: 1-8. PMID 20501999 DOI: 10.1159/000315100  0.371
2010 Wetzel S, Wilk W, Chammaa S, Sperl B, Roth AG, Yektaoglu A, Renner S, Berg T, Arenz C, Giannis A, Oprea TI, Rauh D, Kaiser M, Waldmann H. A scaffold-tree-merging strategy for prospective bioactivity annotation of gamma-pyrones. Angewandte Chemie (International Ed. in English). 49: 3666-70. PMID 20394088 DOI: 10.1002/Anie.200906555  0.593
2010 Kirkegaard T, Roth AG, Petersen NH, Mahalka AK, Olsen OD, Moilanen I, Zylicz A, Knudsen J, Sandhoff K, Arenz C, Kinnunen PK, Nylandsted J, Jäättelä M. Hsp70 stabilizes lysosomes and reverts Niemann-Pick disease-associated lysosomal pathology. Nature. 463: 549-53. PMID 20111001 DOI: 10.1038/Nature08710  0.604
2010 Roth AG, Redmer S, Arenz C. Development of carbohydrate-derived inhibitors of acid sphingomyelinase. Bioorganic & Medicinal Chemistry. 18: 939-44. PMID 20005726 DOI: 10.1016/J.Bmc.2009.11.030  0.376
2009 Roth AG, Drescher D, Yang Y, Redmer S, Uhlig S, Arenz C. Potent and selective inhibition of acid sphingomyelinase by bisphosphonates. Angewandte Chemie (International Ed. in English). 48: 7560-3. PMID 19746379 DOI: 10.1002/Anie.200903288  0.319
2009 Roth AG, Redmer S, Arenz C. Potent inhibition of acid sphingomyelinase by phosphoinositide analogues. Chembiochem : a European Journal of Chemical Biology. 10: 2367-74. PMID 19688786 DOI: 10.1002/Cbic.200900281  0.382
2009 Roth A, Drescher D, Yang Y, Redmer S, Uhlig S, Arenz C. Potente und selektive Inhibition der sauren Sphingomyelinase durch Bisphosphonate Angewandte Chemie. 121: 7697-7700. DOI: 10.1002/Ange.200903288  0.311
2008 Kirkegaard-Sørensen T, Roth A, Moilanen I, Zylicz A, Schmitt E, Grüenberg J, Arenz C, Garrido C, Sandhoff K, Kinnunen PKJ, Nylandsted J, Jäättel M. 45 Interaction between Hsp70 and bis(monoacylglycero)phosphate stabilizes lysosomes and promotes cell survival Apmis. 116: 436-437. DOI: 10.1111/J.1600-0463.2008.00Abs1165_53.X  0.558
2007 Babalola JO, Wendeler M, Breiden B, Arenz C, Schwarzmann G, Locatelli-Hoops S, Sandhoff K. Development of an assay for the intermembrane transfer of cholesterol by Niemann-Pick C2 protein. Biological Chemistry. 388: 617-26. PMID 17552909 DOI: 10.1515/Bc.2007.063  0.584
2003 Diallo M, Arenz C, Schmitz K, Sandhoff K, Schepers U. Long Endogenous dsRNAs Can Induce Complete Gene Silencing in Mammalian Cells and Primary Cultures Oligonucleotides. 13: 381-392. PMID 15000829 DOI: 10.1089/154545703322617069  0.68
2003 Diallo M, Arenz C, Schmitz K, Sandhoff K, Schepers U. RNA interference: analyzing the function of glycoproteins and glycosylating proteins in mammalian cells. Methods in Enzymology. 363: 173-90. PMID 14579575 DOI: 10.1016/S0076-6879(03)01051-6  0.724
2003 Kölzer M, Arenz C, Ferlinz K, Werth N, Schulze H, Klingenstein R, Sandhoff K. Phosphatidylinositol-3,5-Bisphosphate is a potent and selective inhibitor of acid sphingomyelinase. Biological Chemistry. 384: 1293-8. PMID 14515991 DOI: 10.1515/Bc.2003.144  0.639
2003 Arenz C, Schepers U. RNA interference: from an ancient mechanism to a state of the art therapeutic application? Die Naturwissenschaften. 90: 345-59. PMID 12955224 DOI: 10.1007/S00114-003-0441-4  0.72
2002 Arenz C, Thutewohl M, Block O, Waldmann H, Altenbach HJ, Giannis A. Manumycin A and its analogues are irreversible inhibitors of neutral sphingomyelinase. Chembiochem : a European Journal of Chemical Biology. 2: 141-3. PMID 11828438 DOI: 10.1002/1439-7633(20010202)2:2<141::Aid-Cbic141>3.0.Co;2-P  0.644
2001 Arenz C, Gartner M, Wascholowski V, Giannis A. Synthesis and biochemical investigation of scyphostatin analogues as inhibitors of neutral sphingomyelinase Bioorganic and Medicinal Chemistry. 9: 2901-2904. PMID 11597471 DOI: 10.1016/S0968-0896(01)00165-1  0.647
2001 Arenz C, Giannis A. Synthesis of the first selective irreversible inhibitor of neutral sphingomyelinase European Journal of Organic Chemistry. 137-140. DOI: 10.1002/(Sici)1521-3773(20000417)39:8<1440::Aid-Anie1440>3.0.Co;2-R  0.658
2000 Arenz C, Giannis A. Synthese des ersten selektiven irreversiblen Inhibitors der neutralen Sphingomyelinase Angewandte Chemie. 112: 1498-1500. DOI: 10.1002/(Sici)1521-3757(20000417)112:8<1498::Aid-Ange1498>3.0.Co;2-Y  0.637
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