| Year |
Citation |
Score |
| 2023 |
Silva JG, Pais Ferreira D, Dumez A, Wyss T, Veber R, Danilo M, Pinschewer DD, Charmoy M, Held W. Emergence and fate of stem cell-like CD8 T cells during a primary immune response to viral infection. Science Immunology. 8: eadh3113. PMID 37976346 DOI: 10.1126/sciimmunol.adh3113 |
0.461 |
|
| 2023 |
Tillé L, Cropp D, Charmoy M, Reichenbach P, Andreatta M, Wyss T, Bodley G, Crespo I, Nassiri S, Lourenco J, Leblond MM, Lopez-Rodriguez C, Speiser DE, Coukos G, Irving M, ... ... Held W, et al. Activation of the transcription factor NFAT5 in the tumor microenvironment enforces CD8 T cell exhaustion. Nature Immunology. PMID 37709986 DOI: 10.1038/s41590-023-01614-x |
0.417 |
|
| 2023 |
Marx AF, Kallert SM, Brunner TM, Villegas JA, Geier F, Fixemer J, Abreu-Mota T, Reuther P, Bonilla WV, Fadejeva J, Kreutzfeldt M, Wagner I, Aparicio-Domingo P, Scarpellino L, Charmoy M, ... ... Held W, et al. The alarmin interleukin-33 promotes the expansion and preserves the stemness of Tcf-1 CD8 T cells in chronic viral infection. Immunity. PMID 36809763 DOI: 10.1016/j.immuni.2023.01.029 |
0.359 |
|
| 2023 |
Sacirbegovic F, Günther M, Greco A, Zhao D, Wang X, Zhou M, Rosenberger S, Oberbarnscheidt MH, Held W, McNiff J, Jain D, Höfer T, Shlomchik WD. Graft-versus-host disease is locally maintained in target tissues by resident progenitor-like T cells. Immunity. PMID 36720219 DOI: 10.1016/j.immuni.2023.01.003 |
0.313 |
|
| 2022 |
Held W, Luther SA, Petrova TV. Stem-cell-like T cells have a specific entry gate to the tumor. Cancer Cell. 40: 243-245. PMID 35176235 DOI: 10.1016/j.ccell.2022.02.004 |
0.37 |
|
| 2021 |
Charmoy M, Wyss T, Delorenzi M, Held W. PD-1 Tcf1 CD8 T cells from established chronic infection can form memory while retaining a stableimprint of persistent antigen exposure. Cell Reports. 36: 109672. PMID 34496259 DOI: 10.1016/j.celrep.2021.109672 |
0.35 |
|
| 2021 |
Guo Y, Xie YQ, Gao M, Zhao Y, Franco F, Wenes M, Siddiqui I, Bevilacqua A, Wang H, Yang H, Feng B, Xie X, Sabatel CM, Tschumi B, Chaiboonchoe A, ... ... Held W, et al. Metabolic reprogramming of terminally exhausted CD8 T cells by IL-10 enhances anti-tumor immunity. Nature Immunology. PMID 34031618 DOI: 10.1038/s41590-021-00940-2 |
0.376 |
|
| 2021 |
Held W, Speiser DE. Not All Tumor-Infiltrating CD8 T Cells Are Created Equal. Cancer Cell. 39: 145-147. PMID 33561395 DOI: 10.1016/j.ccell.2021.01.015 |
0.388 |
|
| 2020 |
Pais Ferreira D, Silva JG, Wyss T, Fuertes Marraco SA, Scarpellino L, Charmoy M, Maas R, Siddiqui I, Tang L, Joyce JA, Delorenzi M, Luther SA, Speiser DE, Held W. Central memory CD8 T cells derive from stem-like Tcf7 effector cells in the absence of cytotoxic differentiation. Immunity. PMID 33128876 DOI: 10.1016/j.immuni.2020.09.005 |
0.435 |
|
| 2020 |
Welten SPM, Yermanos A, Baumann NS, Wagen F, Oetiker N, Sandu I, Pedrioli A, Oduro JD, Reddy ST, Cicin-Sain L, Held W, Oxenius A. Tcf1 cells are required to maintain the inflationary T cell pool upon MCMV infection. Nature Communications. 11: 2295. PMID 32385253 DOI: 10.1038/S41467-020-16219-3 |
0.533 |
|
| 2020 |
Carmona SJ, Siddiqui I, Bilous M, Held W, Gfeller D. Deciphering the transcriptomic landscape of tumor-infiltrating CD8 lymphocytes in B16 melanoma tumors with single-cell RNA-Seq. Oncoimmunology. 9: 1737369. PMID 32313720 DOI: 10.1080/2162402X.2020.1737369 |
0.381 |
|
| 2019 |
Held W, Siddiqui I, Schaeuble K, Speiser DE. Intratumoral CD8 T cells with stem cell-like properties: Implications for cancer immunotherapy. Science Translational Medicine. 11. PMID 31645454 DOI: 10.1126/Scitranslmed.Aay6863 |
0.483 |
|
| 2019 |
Blank CU, Haining WN, Held W, Hogan PG, Kallies A, Lugli E, Lynn RC, Philip M, Rao A, Restifo NP, Schietinger A, Schumacher TN, Schwartzberg PL, Sharpe AH, Speiser DE, et al. Defining 'T cell exhaustion'. Nature Reviews. Immunology. PMID 31570879 DOI: 10.1038/S41577-019-0221-9 |
0.494 |
|
| 2019 |
Luong-Gardiol N, Siddiqui I, Pizzitola I, Jeevan-Raj B, Charmoy M, Huang Y, Irmisch A, Curtet S, Angelov GS, Danilo M, Juilland M, Bornhauser B, Thome M, Hantschel O, Chalandon Y, ... ... Held W, et al. γ-Catenin-Dependent Signals Maintain BCR-ABL1 B Cell Acute Lymphoblastic Leukemia. Cancer Cell. 35: 649-663.e10. PMID 30991025 DOI: 10.1016/J.Ccell.2019.03.005 |
0.334 |
|
| 2019 |
Niogret C, Miah SMS, Rota G, Fonta NP, Wang H, Held W, Birchmeier W, Sexl V, Yang W, Vivier E, Ho PC, Brossay L, Guarda G. Shp-2 is critical for ERK and metabolic engagement downstream of IL-15 receptor in NK cells. Nature Communications. 10: 1444. PMID 30926899 DOI: 10.1038/S41467-019-09431-3 |
0.398 |
|
| 2019 |
Siddiqui I, Schaeuble K, Chennupati V, Fuertes Marraco SA, Calderon-Copete S, Pais Ferreira D, Carmona SJ, Scarpellino L, Gfeller D, Pradervand S, Luther SA, Speiser DE, Held W. Intratumoral Tcf1PD-1CD8 T Cells with Stem-like Properties Promote Tumor Control in Response to Vaccination and Checkpoint Blockade Immunotherapy. Immunity. 50: 195-211.e10. PMID 30635237 DOI: 10.1016/J.Immuni.2018.12.021 |
0.511 |
|
| 2018 |
Lan Q, Peyvandi S, Duffey N, Huang YT, Barras D, Held W, Richard F, Delorenzi M, Sotiriou C, Desmedt C, Lorusso G, Rüegg C. Type I interferon/IRF7 axis instigates chemotherapy-induced immunological dormancy in breast cancer. Oncogene. PMID 30546090 DOI: 10.1038/S41388-018-0624-2 |
0.326 |
|
| 2018 |
Held W, Jeevan-Raj B, Charmoy M. Transcriptional regulation of murine natural killer cell development, differentiation and maturation. Cellular and Molecular Life Sciences : Cmls. PMID 29959459 DOI: 10.1007/S00018-018-2865-1 |
0.501 |
|
| 2018 |
Danilo M, Chennupati V, Silva JG, Siegert S, Held W. Suppression of Tcf1 by Inflammatory Cytokines Facilitates Effector CD8 T Cell Differentiation. Cell Reports. 22: 2107-2117. PMID 29466737 DOI: 10.1016/J.Celrep.2018.01.072 |
0.509 |
|
| 2017 |
Chennupati V, Held W. Feeling Exhausted? Tuning Irf4 Energizes Dysfunctional T Cells. Immunity. 47: 1009-1011. PMID 29262341 DOI: 10.1016/J.Immuni.2017.11.028 |
0.447 |
|
| 2017 |
Abbuehl JP, Tatarova Z, Held W, Huelsken J. Long-Term Engraftment of Primary Bone Marrow Stromal Cells Repairs Niche Damage and Improves Hematopoietic Stem Cell Transplantation. Cell Stem Cell. 21: 241-255.e6. PMID 28777945 DOI: 10.1016/J.Stem.2017.07.004 |
0.303 |
|
| 2017 |
Jeevan-Raj B, Gehrig J, Charmoy M, Chennupati V, Grandclément C, Angelino P, Delorenzi M, Held W. The Transcription Factor Tcf1 Contributes to Normal NK Cell Development and Function by Limiting the Expression of Granzymes. Cell Reports. 20: 613-626. PMID 28723565 DOI: 10.1016/J.Celrep.2017.06.071 |
0.54 |
|
| 2017 |
Wieland D, Kemming J, Schuch A, Emmerich F, Knolle P, Neumann-Haefelin C, Held W, Zehn D, Hofmann M, Thimme R. TCF1(+) hepatitis C virus-specific CD8(+) T cells are maintained after cessation of chronic antigen stimulation. Nature Communications. 8: 15050. PMID 28466857 DOI: 10.1038/Ncomms15050 |
0.427 |
|
| 2016 |
Utzschneider DT, Charmoy M, Chennupati V, Pousse L, Ferreira DP, Calderon-Copete S, Danilo M, Alfei F, Hofmann M, Wieland D, Pradervand S, Thimme R, Zehn D, Held W. T Cell Factor 1-Expressing Memory-like CD8(+) T Cells Sustain the Immune Response to Chronic Viral Infections. Immunity. 45: 415-27. PMID 27533016 DOI: 10.1016/J.Immuni.2016.07.021 |
0.528 |
|
| 2016 |
Alari-Pahissa E, Grandclément C, Jeevan-Raj B, Leclercq G, Veillette A, Held W. Activation by SLAM Family Receptors Contributes to NK Cell Mediated "Missing-Self" Recognition. Plos One. 11: e0153236. PMID 27054584 DOI: 10.1371/Journal.Pone.0153236 |
0.6 |
|
| 2016 |
Scholz G, Jandus C, Zhang L, Grandclément C, Lopez-Mejia IC, Soneson C, Delorenzi M, Fajas L, Held W, Dormond O, Romero P. Modulation of mTOR Signalling Triggers the Formation of Stem Cell-like Memory T Cells. Ebiomedicine. 4: 50-61. PMID 26981571 DOI: 10.1016/J.Ebiom.2016.01.019 |
0.502 |
|
| 2016 |
Grandclément C, Pick H, Vogel H, Held W. NK Cells Respond to Haptens by the Activation of Calcium Permeable Plasma Membrane Channels. Plos One. 11: e0151031. PMID 26963818 DOI: 10.1371/Journal.Pone.0151031 |
0.498 |
|
| 2016 |
Ludigs K, Jandus C, Utzschneider DT, Staehli F, Bessoles S, Dang AT, Rota G, Castro W, Zehn D, Vivier E, Held W, Romero P, Guarda G. NLRC5 shields T lymphocytes from NK-cell-mediated elimination under inflammatory conditions. Nature Communications. 7: 10554. PMID 26861112 DOI: 10.1038/Ncomms10554 |
0.593 |
|
| 2016 |
Wieland D, Kemming J, Schuch A, Neumann-Haefelin C, Knolle P, Held W, Zehn D, Hofmann M, Thimme R. A TCF1 expressing memory-like population of Hepatitis C virus-specific CD8+ T cells is maintained after DAA-mediated viral elimination Zeitschrift Fur Gastroenterologie. 54: 1343-1404. DOI: 10.1055/S-0036-1597500 |
0.412 |
|
| 2016 |
Wieland D, Schuch A, Held W, Zehn D, Hofmann M, Thimme R. A Memory-Like Subset Dominates the HCV-Specific CD8+ T-Cell Compartment after DAA-Mediated Antigen Removal Journal of Hepatology. 64. DOI: 10.1016/S0168-8278(16)01473-2 |
0.404 |
|
| 2015 |
Hurrell BP, Schuster S, Grün E, Coutaz M, Williams RA, Held W, Malissen B, Malissen M, Yousefi S, Simon HU, Müller AJ, Tacchini-Cottier F. Rapid Sequestration of Leishmania mexicana by Neutrophils Contributes to the Development of Chronic Lesion. Plos Pathogens. 11: e1004929. PMID 26020515 DOI: 10.1371/Journal.Ppat.1004929 |
0.337 |
|
| 2014 |
Alari-Pahissa E, Grandclément C, Jeevan-Raj B, Held W. Inhibitory receptor-mediated regulation of natural killer cells. Critical Reviews in Immunology. 34: 455-65. PMID 25597309 DOI: 10.1615/Critrevimmunol.2014012220 |
0.539 |
|
| 2014 |
Jaworski M, Marsland BJ, Gehrig J, Held W, Favre S, Luther SA, Perroud M, Golshayan D, Gaide O, Thome M. Malt1 protease inactivation efficiently dampens immune responses but causes spontaneous autoimmunity. The Embo Journal. 33: 2765-81. PMID 25319413 DOI: 10.15252/Embj.201488987 |
0.417 |
|
| 2014 |
Boudousquié C, Danilo M, Pousse L, Jeevan-Raj B, Angelov GS, Chennupati V, Zehn D, Held W. Differences in the transduction of canonical Wnt signals demarcate effector and memory CD8 T cells with distinct recall proliferation capacity. Journal of Immunology (Baltimore, Md. : 1950). 193: 2784-91. PMID 25127860 DOI: 10.4049/Jimmunol.1400465 |
0.478 |
|
| 2014 |
Bessoles S, Grandclément C, Alari-Pahissa E, Gehrig J, Jeevan-Raj B, Held W. Adaptations of Natural Killer Cells to Self-MHC Class I. Frontiers in Immunology. 5: 349. PMID 25101089 DOI: 10.3389/Fimmu.2014.00349 |
0.512 |
|
| 2013 |
Bessoles S, Angelov GS, Back J, Leclercq G, Vivier E, Held W. Education of murine NK cells requires both cis and trans recognition of MHC class I molecules. Journal of Immunology (Baltimore, Md. : 1950). 191: 5044-51. PMID 24098052 DOI: 10.4049/Jimmunol.1301971 |
0.528 |
|
| 2013 |
Held W. Inhibitory receptors and their mode of action: key insights from NK cells. Journal of Immunology (Baltimore, Md. : 1950). 191: 3489-90. PMID 24058191 DOI: 10.4049/Jimmunol.1302158 |
0.445 |
|
| 2013 |
Dudda JC, Salaun B, Ji Y, Palmer DC, Monnot GC, Merck E, Boudousquie C, Utzschneider DT, Escobar TM, Perret R, Muljo SA, Hebeisen M, Rufer N, Zehn D, Donda A, ... ... Held W, et al. MicroRNA-155 is required for effector CD8+ T cell responses to virus infection and cancer. Immunity. 38: 742-53. PMID 23601686 DOI: 10.1016/J.Immuni.2012.12.006 |
0.416 |
|
| 2012 |
Held W. Nonclassical NK cell education. Nature Immunology. 13: 1135-7. PMID 23160207 DOI: 10.1038/Ni.2470 |
0.424 |
|
| 2012 |
Khalil H, Peltzer N, Walicki J, Yang JY, Dubuis G, Gardiol N, Held W, Bigliardi P, Marsland B, Liaudet L, Widmann C. Caspase-3 protects stressed organs against cell death. Molecular and Cellular Biology. 32: 4523-33. PMID 22949508 DOI: 10.1128/Mcb.00774-12 |
0.317 |
|
| 2011 |
Back J, Angelov GS, Mariuzza RA, Held W. The interaction with H-2D(d) in cis is associated with a conformational change in the Ly49A NK cell receptor. Frontiers in Immunology. 2: 55. PMID 22566845 DOI: 10.3389/Fimmu.2011.00055 |
0.487 |
|
| 2011 |
Kijima M, Gardiol N, Held W. Natural killer cell mediated missing-self recognition can protect mice from primary chronic myeloid leukemia in vivo. Plos One. 6: e27639. PMID 22132120 DOI: 10.1371/Journal.Pone.0027639 |
0.503 |
|
| 2011 |
Held W, Mariuzza RA. Cis-trans interactions of cell surface receptors: biological roles and structural basis. Cellular and Molecular Life Sciences : Cmls. 68: 3469-78. PMID 21863376 DOI: 10.1007/S00018-011-0798-Z |
0.418 |
|
| 2011 |
Merck E, Lees RK, Voyle RB, Held W, MacDonald HR. Ly49D-mediated ITAM signaling in immature thymocytes impairs development by bypassing the pre-TCR checkpoint. Journal of Immunology (Baltimore, Md. : 1950). 187: 110-7. PMID 21632721 DOI: 10.4049/Jimmunol.1002755 |
0.509 |
|
| 2011 |
Taveirne S, Filtjens J, Van Ammel E, De Colvenaer V, Kerre T, Taghon T, Vandekerckhove B, Plum J, Held W, Leclercq G. Inhibitory receptors specific for MHC class I educate murine NK cells but not CD8αα intestinal intraepithelial T lymphocytes. Blood. 118: 339-47. PMID 21613250 DOI: 10.1182/Blood-2011-01-331124 |
0.478 |
|
| 2011 |
Held W, Kijima M, Angelov G, Bessoles S. The function of natural killer cells: education, reminders and some good memories. Current Opinion in Immunology. 23: 228-33. PMID 21159498 DOI: 10.1016/J.Coi.2010.11.008 |
0.511 |
|
| 2010 |
Held W. A KIR-TLR connection. Blood. 116: 1629-30. PMID 20829375 DOI: 10.1182/Blood-2010-03-272203 |
0.431 |
|
| 2010 |
Jeannet G, Boudousquié C, Gardiol N, Kang J, Huelsken J, Held W. Essential role of the Wnt pathway effector Tcf-1 for the establishment of functional CD8 T cell memory. Proceedings of the National Academy of Sciences of the United States of America. 107: 9777-82. PMID 20457902 DOI: 10.1073/Pnas.0914127107 |
0.49 |
|
| 2010 |
Back J, Scarpellino L, Held W. Probing the interactions of NK cell receptors with ligand expressed in trans and cis. Methods in Molecular Biology (Clifton, N.J.). 612: 313-23. PMID 20033650 DOI: 10.1007/978-1-60761-362-6_21 |
0.441 |
|
| 2010 |
Zhao DM, Yu S, Zhou X, Haring JS, Held W, Badovinac VP, Harty JT, Xue HH. Constitutive activation of Wnt signaling favors generation of memory CD8 T cells. Journal of Immunology (Baltimore, Md. : 1950). 184: 1191-9. PMID 20026746 DOI: 10.4049/Jimmunol.0901199 |
0.525 |
|
| 2009 |
Back J, Malchiodi EL, Cho S, Scarpellino L, Schneider P, Kerzic MC, Mariuzza RA, Held W. Distinct conformations of Ly49 natural killer cell receptors mediate MHC class I recognition in trans and cis. Immunity. 31: 598-608. PMID 19818651 DOI: 10.1016/J.Immuni.2009.07.007 |
0.423 |
|
| 2009 |
Chalifour A, Scarpellino L, Back J, Brodin P, Devèvre E, Gros F, Lévy F, Leclercq G, Höglund P, Beermann F, Held W. A Role for cis Interaction between the Inhibitory Ly49A receptor and MHC class I for natural killer cell education. Immunity. 30: 337-47. PMID 19249231 DOI: 10.1016/J.Immuni.2008.12.019 |
0.505 |
|
| 2008 |
Held W. Tolerance and reactivity of NK cells: two sides of the same coin? European Journal of Immunology. 38: 2930-3. PMID 18979510 DOI: 10.1002/Eji.200838755 |
0.525 |
|
| 2008 |
Van Den Broeck T, Stevenaert F, Taveirne S, Debacker V, Vangestel C, Vandekerckhove B, Taghon T, Matthys P, Plum J, Held W, Dewerchin M, Yokoyama WM, Leclercq G. Ly49E-dependent inhibition of natural killer cells by urokinase plasminogen activator. Blood. 112: 5046-51. PMID 18784372 DOI: 10.1182/Blood-2008-06-164350 |
0.523 |
|
| 2008 |
Held W. Inhibitions in NK-cell maturation. Blood. 112: 8-9. PMID 18574038 DOI: 10.1182/Blood-2008-03-147165 |
0.355 |
|
| 2008 |
Held W, Mariuzza RA. Cis interactions of immunoreceptors with MHC and non-MHC ligands. Nature Reviews. Immunology. 8: 269-78. PMID 18309314 DOI: 10.1038/Nri2278 |
0.431 |
|
| 2008 |
Coudert JD, Scarpellino L, Gros F, Vivier E, Held W. Sustained NKG2D engagement induces cross-tolerance of multiple distinct NK cell activation pathways. Blood. 111: 3571-8. PMID 18198346 DOI: 10.1182/Blood-2007-07-100057 |
0.526 |
|
| 2008 |
Jeannet G, Scheller M, Scarpellino L, Duboux S, Gardiol N, Back J, Kuttler F, Malanchi I, Birchmeier W, Leutz A, Huelsken J, Held W. Long-term, multilineage hematopoiesis occurs in the combined absence of beta-catenin and gamma-catenin. Blood. 111: 142-9. PMID 17906078 DOI: 10.1182/Blood-2007-07-102558 |
0.404 |
|
| 2007 |
Back J, Chalifour A, Scarpellino L, Held W. Stable masking by H-2Dd cis ligand limits Ly49A relocalization to the site of NK cell/target cell contact. Proceedings of the National Academy of Sciences of the United States of America. 104: 3978-83. PMID 17360463 DOI: 10.1073/Pnas.0607418104 |
0.383 |
|
| 2007 |
Scarpellino L, Oeschger F, Guillaume P, Coudert JD, Lévy F, Leclercq G, Held W. Interactions of Ly49 family receptors with MHC class I ligands in trans and cis. Journal of Immunology (Baltimore, Md. : 1950). 178: 1277-84. PMID 17237373 DOI: 10.4049/Jimmunol.178.3.1277 |
0.493 |
|
| 2007 |
Melichar HJ, Narayan K, Der SD, Hiraoka Y, Gardiol N, Jeannet G, Held W, Chambers CA, Kang J. Regulation of gammadelta versus alphabeta T lymphocyte differentiation by the transcription factor SOX13. Science (New York, N.Y.). 315: 230-3. PMID 17218525 DOI: 10.1126/Science.1135344 |
0.484 |
|
| 2006 |
Jeannet G, Coudert JD, Held W. T and B lymphocytes exert distinct effects on the homeostasis of NK cells. European Journal of Immunology. 36: 2725-34. PMID 16955521 DOI: 10.1002/Eji.200636011 |
0.569 |
|
| 2006 |
Coudert JD, Held W. The role of the NKG2D receptor for tumor immunity. Seminars in Cancer Biology. 16: 333-43. PMID 16914326 DOI: 10.1016/J.Semcancer.2006.07.008 |
0.51 |
|
| 2006 |
Huang Z, Xie H, Ioannidis V, Held W, Clevers H, Sadim MS, Sun Z. Transcriptional regulation of CD4 gene expression by T cell factor-1/beta-catenin pathway. Journal of Immunology (Baltimore, Md. : 1950). 176: 4880-7. PMID 16585583 DOI: 10.4049/Jimmunol.176.8.4880 |
0.401 |
|
| 2005 |
Germain C, Larbouret C, Cesson V, Donda A, Held W, Mach JP, Pèlegrin A, Robert B. MHC class I-related chain A conjugated to antitumor antibodies can sensitize tumor cells to specific lysis by natural killer cells. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 11: 7516-22. PMID 16243826 DOI: 10.1158/1078-0432.Ccr-05-0872 |
0.429 |
|
| 2005 |
Goux D, Coudert JD, Maurice D, Scarpellino L, Jeannet G, Piccolo S, Weston K, Huelsken J, Held W. Cooperating pre-T-cell receptor and TCF-1-dependent signals ensure thymocyte survival Blood. 106: 1726-1733. PMID 15890681 DOI: 10.1182/Blood-2005-01-0337 |
0.42 |
|
| 2005 |
Coudert JD, Zimmer J, Tomasello E, Cebecauer M, Colonna M, Vivier E, Held W. Altered NKG2D function in NK cells induced by chronic exposure to NKG2D ligand-expressing tumor cells. Blood. 106: 1711-7. PMID 15886320 DOI: 10.1182/Blood-2005-03-0918 |
0.497 |
|
| 2005 |
Held W, Chalifour A, Coudert JD. Regulation of natural killer cell function: a role for the NK cell's own MHC class I molecules. Medical Microbiology and Immunology. 194: 169-74. PMID 15660246 DOI: 10.1007/S00430-004-0235-0 |
0.474 |
|
| 2004 |
Doucey MA, Scarpellino L, Zimmer J, Guillaume P, Luescher IF, Bron C, Held W. Cis association of Ly49A with MHC class I restricts natural killer cell inhibition. Nature Immunology. 5: 328-36. PMID 14973437 DOI: 10.1038/Ni1043 |
0.48 |
|
| 2003 |
Saurer L, Seibold I, Vallan C, Held W, Mueller C. Cutting edge: stimulation with the cognate self-antigen induces expression of the Ly49A receptor on self-reactive T cells which modulates their responsiveness. Journal of Immunology (Baltimore, Md. : 1950). 171: 6334-8. PMID 14662829 DOI: 10.4049/Jimmunol.171.12.6334 |
0.687 |
|
| 2003 |
Ioannidis V, Kunz B, Tanamachi DM, Scarpellino L, Held W. Initiation and limitation of Ly-49A NK cell receptor acquisition by T cell factor-1. Journal of Immunology (Baltimore, Md. : 1950). 171: 769-75. PMID 12847244 DOI: 10.4049/Jimmunol.171.2.769 |
0.467 |
|
| 2003 |
Held W, Clevers H, Grosschedl R. Redundant functions of TCF-1 and LEF-1 during T and NK cell development, but unique role of TCF-1 for Ly49 NK cell receptor acquisition. European Journal of Immunology. 33: 1393-8. PMID 12731066 DOI: 10.1002/Eji.200323840 |
0.572 |
|
| 2003 |
Voyle RB, Beermann F, Lees RK, Schümann J, Zimmer J, Held W, MacDonald HR. Ligand-dependent inhibition of CD1d-restricted NKT cell development in mice transgenic for the activating receptor Ly49D. The Journal of Experimental Medicine. 197: 919-25. PMID 12682111 DOI: 10.1084/Jem.20021615 |
0.55 |
|
| 2003 |
Held W, Coudert JD, Zimmer J. The NK cell receptor repertoire: formation, adaptation and exploitation. Current Opinion in Immunology. 15: 233-7. PMID 12633675 DOI: 10.1016/S0952-7915(02)00031-6 |
0.526 |
|
| 2002 |
Ferrero I, Held W, Wilson A, Tacchini-Cottier F, Radtke F, MacDonald HR. Mouse CD11c(+) B220(+) Gr1(+) plasmacytoid dendritic cells develop independently of the T-cell lineage. Blood. 100: 2852-7. PMID 12351395 DOI: 10.1182/Blood-2002-01-0214 |
0.498 |
|
| 2002 |
Chambers CA, Kang J, Wu Y, Held W, Raulet DH, Allison JP. The lymphoproliferative defect in CTLA-4-deficient mice is ameliorated by an inhibitory NK cell receptor. Blood. 99: 4509-16. PMID 12036882 DOI: 10.1182/Blood.V99.12.4509 |
0.567 |
|
| 2002 |
Lowin-Kropf B, Kunz B, Schneider P, Held W. A role for the src family kinase Fyn in NK cell activation and the formation of the repertoire of Ly49 receptors. European Journal of Immunology. 32: 773-82. PMID 11870621 DOI: 10.1002/1521-4141(200203)32:3<773::Aid-Immu773>3.0.Co;2-U |
0.509 |
|
| 2001 |
MacDonald HR, Held W. CD8+ T cell development: CD4 to the rescue. Nature Immunology. 2: 1091-1092. PMID 11725294 DOI: 10.1038/Ni1201-1091 |
0.342 |
|
| 2001 |
Ioannidis V, Zimmer J, Beermann F, Held W. Cre Recombinase-Mediated Inactivation of H-2Dd Transgene Expression: Evidence for Partial Missing Self-Recognition by Ly49A NK Cells Journal of Immunology. 167: 6256-6262. PMID 11714788 DOI: 10.4049/Jimmunol.167.11.6256 |
0.341 |
|
| 2001 |
Zimmer J, Ioannidis V, Held W. H-2D Ligand Expression by Ly49A+ Natural Killer (NK) Cells Precludes Ligand Uptake from Environmental Cells: Implications for NK Cell Function Journal of Experimental Medicine. 194: 1531-1539. PMID 11714759 DOI: 10.1084/Jem.194.10.1531 |
0.528 |
|
| 2001 |
Ferrero I, Wilson A, Beermann F, Held W, MacDonald HR. T Cell Receptor Specificity Is Critical for the Development of Epidermal γδ T Cells Journal of Experimental Medicine. 194: 1473-1483. PMID 11714754 DOI: 10.1084/Jem.194.10.1473 |
0.473 |
|
| 2001 |
Ioannidis V, Beermann F, Clevers H, Held W. The beta-catenin--TCF-1 pathway ensures CD4(+)CD8(+) thymocyte survival. Nature Immunology. 2: 691-7. PMID 11477404 DOI: 10.1038/90623 |
0.465 |
|
| 2001 |
Kunz B, Held W. Positive and Negative Roles of the Trans-Acting T Cell Factor-1 for the Acquisition of Distinct Ly-49 MHC Class I Receptors by NK Cells Journal of Immunology. 166: 6181-6187. PMID 11342639 DOI: 10.4049/Jimmunol.166.10.6181 |
0.48 |
|
| 2001 |
Wolfer A, Bakker T, Wilson A, Nicolas M, Ioannidis V, Littman DR, Wilson CB, Held W, MacDonald HR, Radtke F. Inactivation of Notch1 in immature thymocytes does not perturb CD4 or CD8 T cell development Nature Immunology. 2: 235-241. PMID 11224523 DOI: 10.1038/85294 |
0.392 |
|
| 2000 |
Brawand P, Lemonnier FA, MacDonald HR, Cerottini J, Held W. Transgenic expression of Ly49A on T cells impairs a specific antitumor response. Journal of Immunology. 165: 1871-1876. PMID 10925266 DOI: 10.4049/Jimmunol.165.4.1871 |
0.604 |
|
| 2000 |
Lowin-Kropf B, Kunz B, Beermann F, Held W. Impaired natural killing of MHC class I-deficient targets by NK cells expressing a catalytically inactive form of SHP-1. Journal of Immunology. 165: 1314-1321. PMID 10903732 DOI: 10.4049/Jimmunol.165.3.1314 |
0.565 |
|
| 2000 |
Lowin-Kropf B, Held W. Positive Impact of Inhibitory Ly49 Receptor-MHC Class I Interaction on NK Cell Development Journal of Immunology. 165: 91-95. PMID 10861039 DOI: 10.4049/Jimmunol.165.1.91 |
0.552 |
|
| 2000 |
Held W, Lowin-Kropf B, Raulet DH. Generation of short-term murine natural killer cell clones to analyze Ly49 gene expression. Methods in Molecular Biology (Clifton, N.J.). 121: 5-12. PMID 10818712 DOI: 10.1385/1-59259-044-6:5 |
0.399 |
|
| 1999 |
Held W, Kunz B, Lowin-Kropf B, van de Wetering M, Clevers H. Clonal acquisition of the Ly49A NK cell receptor is dependent on the trans-acting factor TCF-1. Immunity. 11: 433-42. PMID 10549625 DOI: 10.1016/S1074-7613(00)80118-1 |
0.532 |
|
| 1999 |
Zerrahn J, Volkmann A, Coles MC, Held W, Lemonnier FA, Raulet DH. Class I MHC molecules on hematopoietic cells can support intrathymic positive selection of T cell receptor transgenic T cells. Proceedings of the National Academy of Sciences of the United States of America. 96: 11470-5. PMID 10500200 DOI: 10.1073/Pnas.96.20.11470 |
0.582 |
|
| 1999 |
Held W, Kunz B, Ioannidis V, Lowin-Kropf B. Mono-allelic Ly49 NK cell receptor expression. Seminars in Immunology. 11: 349-355. PMID 10497089 DOI: 10.1006/Smim.1999.0191 |
0.449 |
|
| 1998 |
Held W, Kunz B. An allele-specific, stochastic gene expression process controls the expression of multiple Ly49 family genes and generates a diverse, MHC-specific NK cell receptor repertoire. European Journal of Immunology. 28: 2407-2416. PMID 9710218 DOI: 10.1002/(Sici)1521-4141(199808)28:08<2407::Aid-Immu2407>3.0.Co;2-D |
0.46 |
|
| 1998 |
Robson MacDonald H, Lees RK, Held W. Developmentally regulated extinction of Ly-49 receptor expression permits maturation and selection of NK1.1+ T cells. The Journal of Experimental Medicine. 187: 2109-14. PMID 9625772 DOI: 10.1084/Jem.187.12.2109 |
0.582 |
|
| 1997 |
Held W, Raulet DH. Expression of the Ly49A gene in murine natural killer cell clones is predominantly but not exclusively mono-allelic. European Journal of Immunology. 27: 2876-84. PMID 9394813 DOI: 10.1002/Eji.1830271120 |
0.421 |
|
| 1997 |
Held W, Raulet DH. Ly49A transgenic mice provide evidence for a major histocompatibility complex-dependent education process in natural killer cell development. The Journal of Experimental Medicine. 185: 2079-88. PMID 9182679 DOI: 10.1084/Jem.185.12.2079 |
0.438 |
|
| 1997 |
Raulet DH, Held W, Correa I, Dorfman JR, Wu MF, Corral L. Specificity, tolerance and developmental regulation of natural killer cells defined by expression of class I-specific Ly49 receptors. Immunological Reviews. 155: 41-52. PMID 9059881 DOI: 10.1111/J.1600-065X.1997.Tb00938.X |
0.444 |
|
| 1997 |
Zerrahn J, Held W, Raulet DH. The MHC reactivity of the T cell repertoire prior to positive and negative selection. Cell. 88: 627-36. PMID 9054502 DOI: 10.1016/S0092-8674(00)81905-4 |
0.347 |
|
| 1996 |
Held W, Cado D, Raulet DH. Transgenic expression of the Ly49A natural killer cell receptor confers class I major histocompatibility complex (MHC)-specific inhibition and prevents bone marrow allograft rejection. The Journal of Experimental Medicine. 184: 2037-41. PMID 8920892 DOI: 10.1084/Jem.184.5.2037 |
0.505 |
|
| 1996 |
Held W, Dorfman JR, Wu MF, Raulet DH. Major histocompatibility complex class I-dependent skewing of the natural killer cell Ly49 receptor repertoire. European Journal of Immunology. 26: 2286-92. PMID 8898935 DOI: 10.1002/Eji.1830261003 |
0.424 |
|
| 1995 |
Mueller C, Held W, Imboden MA, Carnaud C. Accelerated β-cell Destruction in Adoptively Transferred Autoimmune Diabetes Correlates With an Increased Expression of the Genes Coding for TNF-α and Granzyme A in the Intra-Islet Infiltrates Diabetes. 44: 112-117. PMID 7813805 DOI: 10.2337/Diab.44.1.112 |
0.644 |
|
| 1995 |
Raulet DH, Held W. Natural killer cell receptors: the offs and ons of NK cell recognition. Cell. 82: 697-700. PMID 7671299 DOI: 10.1016/0092-8674(95)90466-2 |
0.484 |
|
| 1995 |
Held W, Roland J, Raulet DH. Allelic exclusion of Ly49-family genes encoding class I MHC-specific receptors on NK cells. Nature. 376: 355-8. PMID 7630404 DOI: 10.1038/376355A0 |
0.445 |
|
| 1995 |
Waanders GA, Lees RK, Held W, MacDonald HR. Quantitation of endogenous mouse mammary tumor virus superantigen expression by lymphocyte subsets. European Journal of Immunology. 25: 2632-7. PMID 7589137 DOI: 10.1002/Eji.1830250934 |
0.537 |
|
| 1994 |
Held W, Acha-Orbea H, MacDonald HR, Waanders GA. Superantigens and retroviral infection: insights from mouse mammary tumor virus Immunology Today. 15: 184-190. PMID 8198710 DOI: 10.1016/0167-5699(94)90317-4 |
0.493 |
|
| 1994 |
Wilson A, Held W, MacDonald HR. Two waves of recombinase gene expression in developing thymocytes. Journal of Experimental Medicine. 179: 1355-1360. PMID 8145048 DOI: 10.1084/Jem.179.4.1355 |
0.438 |
|
| 1994 |
Held W, Waandere GA, MacDonald HR, Acha-Orbea H. MHC class II hierarchy of superantigen presentation predicts efficiency of infection with mouse mammary tumor virus. International Immunology. 6: 1403-1407. PMID 7819149 DOI: 10.1093/Intimm/6.9.1403 |
0.436 |
|
| 1994 |
Held W, Waanders GA, Acha-Orbea H, MacDonald HR. Reverse transcriptase-dependent and -independent phases of infection with mouse mammary tumor virus: implications for superantigen function. Journal of Experimental Medicine. 180: 2347-2351. PMID 7525852 DOI: 10.1084/Jem.180.6.2347 |
0.43 |
|
| 1993 |
Held W, Waanders GA, Shakhov AN, Scarpellino L, Acha-Orbea H, MacDonald HR. Superantigen-induced immune stimulation amplifies mouse mammary tumor virus infection and allows virus transmission Cell. 74: 529-540. PMID 8394220 DOI: 10.1016/0092-8674(93)80054-I |
0.483 |
|
| 1993 |
Waanders GA, Shakhov AN, Held W, Karapetian O, Acha-Orbea H, MacDonald HR. Peripheral T cell activation and deletion induced by transfer of lymphocyte subsets expressing endogenous or exogenous mouse mammary tumor virus. Journal of Experimental Medicine. 177: 1359-1366. PMID 8386743 DOI: 10.1084/Jem.177.5.1359 |
0.58 |
|
| 1993 |
Held W, Shakhov AN, Izui S, Waanders GA, Scarpellino L, MacDonald HR, Acha-Orbea H. Superantigen-reactive CD4+ T cells are required to stimulate B cells after infection with mouse mammary tumor virus. Journal of Experimental Medicine. 177: 359-366. PMID 8093892 DOI: 10.1084/Jem.177.2.359 |
0.514 |
|
| 1993 |
Held W, Meyermann R, Qin Y, Mueller C. Perforin and Tumor Necrosis Factor α in the Pathogenesis of Experimental Allergic Encephalomyelitis: Comparison of Autoantigen Induced and Transferred Disease in Lewis Rats Journal of Autoimmunity. 6: 311-322. PMID 7691064 DOI: 10.1006/Jaut.1993.1027 |
0.604 |
|
| 1992 |
Acha-Orbea H, Held W, Scarpellino L, Shakhov AN. Mls: a link between immunology and retrovirology. International Reviews of Immunology. 8: 327-336. PMID 1351535 DOI: 10.3109/08830189209053516 |
0.307 |
|
| 1992 |
Acha-Orbea H, Scarpellino L, Shakhov AN, Held W, MacDonald HR. Inhibition of mouse mammary tumor virus-induced T cell responses in vivo by antibodies to an open reading frame protein. Journal of Experimental Medicine. 176: 1769-1772. PMID 1334118 DOI: 10.1084/Jem.176.6.1769 |
0.412 |
|
| 1992 |
Held W, Shakhov AN, Waanders G, Scarpellino L, Luethy R, Kraehenbuhl JP, MacDonald HR, Acha-Orbea H. An exogenous mouse mammary tumor virus with properties of Mls-1a (Mtv-7). Journal of Experimental Medicine. 175: 1623-1633. PMID 1316932 DOI: 10.1084/Jem.175.6.1623 |
0.464 |
|
| 1991 |
Held W, MacDonald HR, Mueller C. Expression of genes encoding cytotoxic cell-associated serine proteases in thymocytes. International Immunology. 2: 57-62. PMID 2150921 DOI: 10.1093/Intimm/2.1.57 |
0.64 |
|
| 1990 |
Held W, MacDonald HR, Weissman IL, Hess MW, Mueller C. Genes encoding tumor necrosis factor alpha and granzyme A are expressed during development of autoimmune diabetes. Proceedings of the National Academy of Sciences of the United States of America. 87: 2239-43. PMID 2179951 DOI: 10.1073/Pnas.87.6.2239 |
0.556 |
|
| 1990 |
Held W, Mueller C, MacDonald HR. Expression of T cell receptor genes in the thymus: localization of transcripts in situ and comparison of mature and immature subsets. European Journal of Immunology. 20: 2133-6. PMID 2120074 DOI: 10.1002/EJI.1830200936 |
0.563 |
|
| 1989 |
Müller C, Kägi D, Aebischer T, Odermatt B, Held W, Podack ER, Zinkernagel RM, Hengartner H. Detection of perforin and granzyme A mRNA in infiltrating cells during infection of mice with lymphocytic choriomeningitis virus. European Journal of Immunology. 19: 1253-9. PMID 2668013 DOI: 10.1002/Eji.1830190716 |
0.487 |
|
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