Kate Ryman - Publications

Affiliations: 
Center for Vaccine Research University of Pittsburgh, Pittsburgh, PA, United States 

47 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Weiss CM, Trobaugh DW, Sun C, Lucas TM, Diamond MS, Ryman KD, Klimstra WB. The Interferon-Induced Exonuclease ISG20 Exerts Antiviral Activity through Upregulation of Type I Interferon Response Proteins. Msphere. 3. PMID 30232164 DOI: 10.1128/mSphere.00209-18  0.403
2018 Lane WC, Dunn MD, Gardner CL, Lam LKM, Watson AM, Hartman AL, Ryman KD, Klimstra WB. The Efficacy of the Interferon Alpha/Beta Response versus Arboviruses Is Temperature Dependent. Mbio. 9. PMID 29691338 DOI: 10.1128/Mbio.00535-18  0.482
2018 Lam LKM, Watson AM, Ryman KD, Klimstra WB. Gamma-interferon exerts a critical early restriction on replication and dissemination of yellow fever virus vaccine strain 17D-204. Npj Vaccines. 3: 5. PMID 29387474 DOI: 10.1038/s41541-017-0039-z  0.577
2017 Duangkhae P, Erdos G, Ryman KD, Watkins SC, Falo LD, Marques ETA, Barratt-Boyes SM. Interplay between Keratinocytes and Myeloid Cells Drives Dengue Virus Spread in Human Skin. The Journal of Investigative Dermatology. PMID 29106931 DOI: 10.1016/J.Jid.2017.10.018  0.42
2017 Gardner CL, Sun C, Luke T, Raviprakash K, Wu H, Jiao JA, Sullivan E, Reed DS, Ryman KD, Klimstra WB. Antibody preparations from human transchromosomic cows exhibit prophylactic and therapeutic efficacy versus Venezuelan equine encephalitis virus. Journal of Virology. PMID 28468884 DOI: 10.1128/Jvi.00226-17  0.424
2016 Watson AM, Lam LK, Klimstra WB, Ryman KD. The 17D-204 Vaccine Strain-Induced Protection against Virulent Yellow Fever Virus Is Mediated by Humoral Immunity and CD4+ but not CD8+ T Cells. Plos Pathogens. 12: e1005786. PMID 27463517 DOI: 10.1371/Journal.Ppat.1005786  0.481
2016 Tree MO, McKellar DR, Kieft KJ, Watson AM, Ryman KD, Conway MJ. Insect-specific flavivirus infection is restricted by innate immunity in the vertebrate host. Virology. 497: 81-91. PMID 27433779 DOI: 10.1016/J.Virol.2016.07.005  0.552
2016 Bhalla N, Sun C, Metthew Lam LK, Gardner CL, Ryman KD, Klimstra WB. Host translation shutoff mediated by non-structural protein 2 is a critical factor in the antiviral state resistance of Venezuelan equine encephalitis virus. Virology. 496: 147-165. PMID 27318152 DOI: 10.1016/J.Virol.2016.06.005  0.368
2016 Gardner CL, Trobaugh DW, Ryman KD, Klimstra WB. Electroporation of Alphavirus RNA Translational Reporters into Fibroblastic and Myeloid Cells as a Tool to Study the Innate Immune System. Methods in Molecular Biology (Clifton, N.J.). 1428: 127-37. PMID 27236796 DOI: 10.1007/978-1-4939-3625-0_8  0.342
2014 Trobaugh DW, Ryman KD, Klimstra WB. Can understanding the virulence mechanisms of RNA viruses lead us to a vaccine against eastern equine encephalitis virus and other alphaviruses? Expert Review of Vaccines. 13: 1423-5. PMID 25073901 DOI: 10.1586/14760584.2014.944168  0.358
2014 Ryman KD, Klimstra WB. Closing the gap between viral and noninfectious arthritis. Proceedings of the National Academy of Sciences of the United States of America. 111: 5767-8. PMID 24733902 DOI: 10.1073/Pnas.1404206111  0.397
2014 Gardner CL, Hritz J, Sun C, Vanlandingham DL, Song TY, Ghedin E, Higgs S, Klimstra WB, Ryman KD. Deliberate attenuation of chikungunya virus by adaptation to heparan sulfate-dependent infectivity: a model for rational arboviral vaccine design. Plos Neglected Tropical Diseases. 8: e2719. PMID 24587470 DOI: 10.1371/Journal.Pntd.0002719  0.465
2014 Trobaugh DW, Gardner CL, Sun C, Haddow AD, Wang E, Chapnik E, Mildner A, Weaver SC, Ryman KD, Klimstra WB. RNA viruses can hijack vertebrate microRNAs to suppress innate immunity. Nature. 506: 245-8. PMID 24352241 DOI: 10.1038/Nature12869  0.317
2014 Sun C, Gardner CL, Watson AM, Ryman KD, Klimstra WB. Stable, high-level expression of reporter proteins from improved alphavirus expression vectors to track replication and dissemination during encephalitic and arthritogenic disease. Journal of Virology. 88: 2035-46. PMID 24307590 DOI: 10.1128/Jvi.02990-13  0.539
2014 Conway MJ, Watson AM, Colpitts TM, Dragovic SM, Li Z, Wang P, Feitosa F, Shepherd DT, Ryman KD, Klimstra WB, Anderson JF, Fikrig E. Mosquito saliva serine protease enhances dissemination of dengue virus into the mammalian host. Journal of Virology. 88: 164-75. PMID 24131723 DOI: 10.1128/Jvi.02235-13  0.569
2012 Gardner CL, Burke CW, Higgs ST, Klimstra WB, Ryman KD. Interferon-alpha/beta deficiency greatly exacerbates arthritogenic disease in mice infected with wild-type chikungunya virus but not with the cell culture-adapted live-attenuated 181/25 vaccine candidate. Virology. 425: 103-12. PMID 22305131 DOI: 10.1016/J.Virol.2011.12.020  0.466
2011 Gardner CL, Ebel GD, Ryman KD, Klimstra WB. Heparan sulfate binding by natural eastern equine encephalitis viruses promotes neurovirulence Proceedings of the National Academy of Sciences of the United States of America. 108: 16026-16031. PMID 21896745 DOI: 10.1073/Pnas.1110617108  0.305
2010 Gardner CL, Ryman KD. Yellow fever: a reemerging threat. Clinics in Laboratory Medicine. 30: 237-60. PMID 20513550 DOI: 10.1016/j.cll.2010.01.001  0.343
2009 Meier KC, Gardner CL, Khoretonenko MV, Klimstra WB, Ryman KD. A mouse model for studying viscerotropic disease caused by yellow fever virus infection. Plos Pathogens. 5: e1000614. PMID 19816561 DOI: 10.1371/Journal.Ppat.1000614  0.468
2009 Burke CW, Gardner CL, Steffan JJ, Ryman KD, Klimstra WB. Characteristics of alpha/beta interferon induction after infection of murine fibroblasts with wild-type and mutant alphaviruses. Virology. 395: 121-32. PMID 19782381 DOI: 10.1016/J.Virol.2009.08.039  0.339
2009 Yin J, Gardner CL, Burke CW, Ryman KD, Klimstra WB. Similarities and differences in antagonism of neuron alpha/beta interferon responses by Venezuelan equine encephalitis and Sindbis alphaviruses. Journal of Virology. 83: 10036-47. PMID 19641001 DOI: 10.1128/Jvi.01209-09  0.317
2009 Gardner CL, Yin J, Burke CW, Klimstra WB, Ryman KD. Type I interferon induction is correlated with attenuation of a South American eastern equine encephalitis virus strain in mice. Virology. 390: 338-47. PMID 19539968 DOI: 10.1016/J.Virol.2009.05.030  0.339
2008 Ryman KD, Klimstra WB. Host responses to alphavirus infection. Immunological Reviews. 225: 27-45. PMID 18837774 DOI: 10.1111/J.1600-065X.2008.00670.X  0.449
2008 Gardner CL, Burke CW, Tesfay MZ, Glass PJ, Klimstra WB, Ryman KD. Eastern and Venezuelan equine encephalitis viruses differ in their ability to infect dendritic cells and macrophages: impact of altered cell tropism on pathogenesis. Journal of Virology. 82: 10634-46. PMID 18768986 DOI: 10.1128/Jvi.01323-08  0.417
2008 Tesfay MZ, Yin J, Gardner CL, Khoretonenko MV, Korneeva NL, Rhoads RE, Ryman KD, Klimstra WB. Alpha/beta interferon inhibits cap-dependent translation of viral but not cellular mRNA by a PKR-independent mechanism. Journal of Virology. 82: 2620-30. PMID 18160435 DOI: 10.1128/Jvi.01784-07  0.312
2007 Zhang Y, Burke CW, Ryman KD, Klimstra WB. Identification and characterization of interferon-induced proteins that inhibit alphavirus replication. Journal of Virology. 81: 11246-55. PMID 17686841 DOI: 10.1128/Jvi.01282-07  0.331
2007 Ryman KD, Meier KC, Gardner CL, Adegboyega PA, Klimstra WB. Non-pathogenic Sindbis virus causes hemorrhagic fever in the absence of alpha/beta and gamma interferons. Virology. 368: 273-85. PMID 17681583 DOI: 10.1016/J.Virol.2007.06.039  0.362
2007 Ryman KD, Gardner CL, Meier KC, Biron CA, Johnston RE, Klimstra WB. Early restriction of alphavirus replication and dissemination contributes to age-dependent attenuation of systemic hyperinflammatory disease. The Journal of General Virology. 88: 518-29. PMID 17251570 DOI: 10.1099/Vir.0.82359-0  0.485
2005 Klimstra WB, Williams JC, Ryman KD, Heidner HW. Targeting Sindbis virus-based vectors to Fc receptor-positive cell types. Virology. 338: 9-21. PMID 15922395 DOI: 10.1016/J.Virol.2005.04.039  0.314
2005 Ryman KD, Meier KC, Nangle EM, Ragsdale SL, Korneeva NL, Rhoads RE, MacDonald MR, Klimstra WB. Sindbis virus translation is inhibited by a PKR/RNase L-independent effector induced by alpha/beta interferon priming of dendritic cells. Journal of Virology. 79: 1487-99. PMID 15650175 DOI: 10.1128/JVI.79.3.1487-1499.2005  0.35
2004 Paredes AM, Ferreira D, Horton M, Saad A, Tsuruta H, Johnston R, Klimstra W, Ryman K, Hernandez R, Chiu W, Brown DT. Conformational changes in Sindbis virions resulting from exposure to low pH and interactions with cells suggest that cell penetration may occur at the cell surface in the absence of membrane fusion. Virology. 324: 373-86. PMID 15207623 DOI: 10.1016/J.Virol.2004.03.046  0.362
2004 Ryman KD, Klimstra WB, Johnston RE. Attenuation of Sindbis virus variants incorporating uncleaved PE2 glycoprotein is correlated with attachment to cell-surface heparan sulfate. Virology. 322: 1-12. PMID 15063111 DOI: 10.1016/J.Virol.2004.01.003  0.345
2003 Klimstra WB, Nangle EM, Smith MS, Yurochko AD, Ryman KD. DC-SIGN and L-SIGN Can Act as Attachment Receptors for Alphaviruses and Distinguish between Mosquito Cell- and Mammalian Cell-Derived Viruses Journal of Virology. 77: 12022-12032. PMID 14581539 DOI: 10.1128/Jvi.78.14.7862.2004  0.376
2003 Thomas JM, Klimstra WB, Ryman KD, Heidner HW. Sindbis virus vectors designed to express a foreign protein as a cleavable component of the viral structural polyprotein. Journal of Virology. 77: 5598-606. PMID 12719552 DOI: 10.1128/Jvi.77.10.5598-5606.2003  0.321
2002 Ryman KD, White LJ, Johnston RE, Klimstra WB. Effects of PKR/RNase L-dependent and alternative antiviral pathways on alphavirus replication and pathogenesis. Viral Immunology. 15: 53-76. PMID 11952147 DOI: 10.1089/088282402317340233  0.374
2001 Smit JM, Klimstra WB, Ryman KD, Bittman R, Johnston RE, Wilschut J. PE2 cleavage mutants of Sindbis virus: correlation between viral infectivity and pH-dependent membrane fusion activation of the spike heterodimer. Journal of Virology. 75: 11196-204. PMID 11602759 DOI: 10.1128/Jvi.75.22.11196-11204.2001  0.366
2000 Ryman KD, Klimstra WB, Nguyen KB, Biron CA, Johnston RE. Alpha/beta interferon protects adult mice from fatal Sindbis virus infection and is an important determinant of cell and tissue tropism. Journal of Virology. 74: 3366-78. PMID 10708454 DOI: 10.1128/Jvi.74.7.3366-3378.2000  0.374
1999 Klimstra WB, Ryman KD, Bernard KA, Nguyen KB, Biron CA, Johnston RE. Infection of neonatal mice with sindbis virus results in a systemic inflammatory response syndrome. Journal of Virology. 73: 10387-98. PMID 10559357 DOI: 10.1128/Jvi.73.12.10387-10398.1999  0.352
1999 Dunster LM, Wang H, Ryman KD, Miller BR, Watowich SJ, Minor PD, Barrett AD. Molecular and biological changes associated with HeLa cell attenuation of wild-type yellow fever virus. Virology. 261: 309-18. PMID 10497116 DOI: 10.1006/Viro.1999.9873  0.393
1998 Xie H, Ryman KD, Campbell GA, Barrett AD. Mutation in NS5 protein attenuates mouse neurovirulence of yellow fever 17D vaccine virus. The Journal of General Virology. 79: 1895-9. PMID 9714237 DOI: 10.1099/0022-1317-79-8-1895  0.332
1998 Klimstra WB, Ryman KD, Johnston RE. Adaptation of Sindbis virus to BHK cells selects for use of heparan sulfate as an attachment receptor. Journal of Virology. 72: 7357-66. PMID 9696832 DOI: 10.1128/Jvi.72.9.7357-7366.1998  0.328
1998 Ryman KD, Ledger TN, Campbell GA, Watowich SJ, Barrett AD. Mutation in a 17D-204 vaccine substrain-specific envelope protein epitope alters the pathogenesis of yellow fever virus in mice. Virology. 244: 59-65. PMID 9581778 DOI: 10.1006/Viro.1998.9057  0.364
1997 Wang H, Jennings AD, Ryman KD, Late CM, Wang E, Ni H, Minor PD, Barrett AD. Genetic variation among strains of wild-type yellow fever virus from Senegal. The Journal of General Virology. 1349-52. PMID 9191928 DOI: 10.1099/0022-1317-78-6-1349  0.376
1997 Ryman KD, Xie H, Ledger TN, Campbell GA, Barrett AD. Antigenic variants of yellow fever virus with an altered neurovirulence phenotype in mice. Virology. 230: 376-80. PMID 9143294 DOI: 10.1006/Viro.1997.8496  0.368
1997 Trgovcich J, Ryman K, Extrom P, Eldridge JC, Aronson JF, Johnston RE. Sindbis virus infection of neonatal mice results in a severe stress response. Virology. 227: 234-8. PMID 9007079 DOI: 10.1006/Viro.1996.8289  0.47
1995 Cao JX, Ni H, Wills MR, Campbell GA, Sil BK, Ryman KD, Kitchen I, Barrett AD. Passage of Japanese encephalitis virus in HeLa cells results in attenuation of virulence in mice. The Journal of General Virology. 76: 2757-64. PMID 7595383 DOI: 10.1099/0022-1317-76-11-2757  0.356
1995 Wang E, Ryman KD, Jennings AD, Wood DJ, Taffs F, Minor PD, Sanders PG, Barrett AD. Comparison of the genomes of the wild-type French viscerotropic strain of yellow fever virus with its vaccine derivative French neurotropic vaccine. The Journal of General Virology. 2749-55. PMID 7595382 DOI: 10.1099/0022-1317-76-11-2749  0.309
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