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P. Roy Vagelos, M.D. - Publications

Affiliations: 
Regeneron Pharmaceuticals, Inc. 
 1966-1975 Biological chemistry Washington University School of Medicine, St. Louis, MO, United States 
Area:
fatty acid biosynthesis and metabolism
Website:
http://history.nih.gov/exhibits/stadtman/bios.htm#vagelos
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75 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 York JD, Vagelos PR. A tribute to Philip W. Majerus. The Journal of Clinical Investigation. 126: 3161-4. PMID 27584729 DOI: 10.1172/JCI89724  0.492
1978 Doi O, Doi F, Schroeder F, Alberts AW, Vagelos PR. Manipulation of fatty acid composition of membrane phospholipid and its effects on cell growth in mouse LM cells Bba - Biomembranes. 509: 239-250. PMID 656411 DOI: 10.1016/0005-2736(78)90044-5  0.495
1977 Sutton MR, Fall RR, Nervi AM, Alberts AW, Vagelos PR, Bradshaw RA. Amino acid sequence of Escherichia coli biotin carboxyl carrier protein (9100) Journal of Biological Chemistry. 252: 3934-3940. PMID 324999  0.301
1976 Schroeder F, Vagelos PR. Effects of phospholipid base analogues on the subcellular membrane ether composition of suspension cultured LM cells. Biochimica Et Biophysica Acta. 441: 239-54. PMID 986179 DOI: 10.1016/0005-2760(76)90167-3  0.305
1976 Volpe JJ, Vagelos PR. Mechanisms and regulation of biosynthesis of saturated fatty acids. Physiological Reviews. 56: 339-417. PMID 6981  0.352
1976 Chang TY, Vagelos PR. Isolation and characterization of an unsaturated fatty acid requiring mutant of cultured mammalian cells Proceedings of the National Academy of Sciences of the United States of America. 73: 24-28. PMID 1750  0.348
1975 Ferguson KA, Glaser M, Bayer WH, Vagelos PR. Alteration of fatty acid composition of LM cells by lipid supplementation and temperature. Biochemistry. 14: 146-51. PMID 1167335  0.366
1975 Rosenfeld IS, D'Agnolo G, Vagelos PR. Identification and quantitation of acyl thioesters by thin-layer chromatography of hydroxamic acid derivatives Analytical Biochemistry. 64: 221-228. PMID 1137086 DOI: 10.1016/0003-2697(75)90422-4  0.398
1975 Prescott DJ, Elovson J, Vagelos PR. Acyl carrier protein synthetase. Methods in Enzymology. 35: 95-101. PMID 1091814 DOI: 10.1016/0076-6879(75)35143-4  0.345
1975 Alberts AW, Strauss AW, Hennessy S, Vagelos PR. Regulation of synthesis of hepatic fatty acid synthetase: binding of fatty acid synthetase antibodies to polysomes Proceedings of the National Academy of Sciences of the United States of America. 72: 3956-3960. PMID 1060077  0.344
1975 D'Agnolo G, Rosenfeld IS, Vagelos PR. Multiple forms of β ketoacyl acyl carrier protein synthetase in Escherichia coli Journal of Biological Chemistry. 250: 5289-5294. PMID 237914  0.403
1975 Fall RR, Vagelos PR. Biotin carboxyl carrier protein from Escherichia coli. Methods in Enzymology. 35: 17-25. PMID 235698 DOI: 10.1016/0076-6879(75)35133-1  0.424
1975 Elovson J, Vagelos PR. Occurrence of apoAcyl carrier protein and an S-Alkylation-resistant form of holoAcyl carrier protein in Escherichia coli Archives of Biochemistry and Biophysics. 168: 490-497. PMID 166621 DOI: 10.1016/0003-9861(75)90279-9  0.398
1975 Ferguson KA, Glaser M, Bayer WH, Vagelos PR. Alteration of fatty acid composition of LM cells by lipid supplementation and temperature Biochemistry. 14: 146-151.  0.311
1974 Silbert DF, Vagelos PR. Systems for membrane alteration: unsaturated fatty acid auxotroph of Escherichia coli. Methods in Enzymology. 32: 856-64. PMID 4614011  0.735
1974 Kent C, Schimmel SD, Vagelos PR. Lipid composition of plasma membranes from developing chick muscle cells in culture Biochimica Et Biophysica Acta (Bba)/Lipids and Lipid Metabolism. 360: 312-321. PMID 4278181 DOI: 10.1016/0005-2760(74)90061-7  0.352
1974 Volpe JJ, Vagelos PR. Regulation of mammalian fatty-acid synthetase. The roles of carbohydrate and insulin. Proceedings of the National Academy of Sciences of the United States of America. 71: 889-93. PMID 4274563 DOI: 10.1073/Pnas.71.3.889  0.349
1974 Vagelos PR. Vitamins and their carrier proteins in fatty acid synthesis. Harvey Lectures. 70: 21-56. PMID 4157196  0.374
1974 Silbert DF, Vagelos PR. [84] Systems for membrane alteration: unsaturated fatty acid auxotroph of Escherichia coli Methods in Enzymology. 32: 856-864. DOI: 10.1016/0076-6879(74)32087-3  0.735
1973 Volpe JJ, Vagelos PR. Fatty acid synthetase of mammalian brain, liver and adipose tissue. Regulation by prosthetic group turnover. Biochimica Et Biophysica Acta. 326: 293-304. PMID 4776436 DOI: 10.1016/0005-2760(73)90131-8  0.41
1973 D'agnony G, Rosenfeld IS, Awaya J, Omura S, Vagelos PR. Inhibition of fatty acid synthesis by the antibiotic cerulenin. Specific inactivation of β-ketoacyl-acyl carrier protein synthetase Biochimica Et Biophysica Acta (Bba)/Lipids and Lipid Metabolism. 326: 155-166. PMID 4587717 DOI: 10.1016/0005-2760(73)90241-5  0.472
1973 Glaser M, Bayer WH, Bell RM, Vagelos PR. Regulation of macromolecular biosynthesis in a mutant of Escherichia coli defective in membrane phospholipid biosynthesis. Proceedings of the National Academy of Sciences of the United States of America. 70: 385-389. PMID 4568726 DOI: 10.1073/Pnas.70.2.385  0.561
1973 Volpe JJ, Vagelos PR. Saturated fatty acid biosynthesis and its regulation. Annual Review of Biochemistry. 42: 21-60. PMID 4147183 DOI: 10.1146/Annurev.Bi.42.070173.000321  0.376
1973 Hancock WS, Prescott DJ, Vagelos PR, Marshall GR. Solvation of the polymer matrix. Source of truncated and failure sequences in solid phase synthesis The Journal of Organic Chemistry. 38: 774-781. DOI: 10.1021/Jo00944A033  0.449
1973 Vagelos PR. 5 Acyl Group Transfer (Acyl Carrier Protein) Enzymes. 8: 155-199. DOI: 10.1016/S1874-6047(08)60065-7  0.499
1973 HANCOCK WS, PRESCOTT DJ, VAGELOS PR, MARSHALL GR. ChemInform Abstract: SOLVATISIERUNG DER POLYMER-MATRIX, DIE QUELLE FUER VERSTUEMMELTE UND ABGELOESTE SEQUENZEN BEI DER FESTPHASEN-SYNTH. Chemischer Informationsdienst. 4: no-no. DOI: 10.1002/Chin.197322461  0.378
1972 Alberts AW, Bell RM, Vagelos PR. Acyl carrier protein. XV. Studies of -ketoacyl-acyl carrier protein synthetase. Journal of Biological Chemistry. 247: 3190-3198. PMID 5027749  0.504
1972 Roncari DA, Bradshaw RA, Vagelos PR. Acyl carrier protein. XIX. Amino acid sequence of liver fatty acid synthetase peptides containing 4'-phosphopantetheine. Journal of Biological Chemistry. 247: 6234-6242. PMID 4568609  0.345
1972 Birge CH, Vagelos PR. Acyl carrier protein. XVI. Intermediate reactions of unsaturated fatty acid synthesis in Escherichia coli and studies of fab B mutants. Journal of Biological Chemistry. 247: 4921-4929. PMID 4560494  0.391
1972 Bell RM, Mavis RD, Vagelos PR. Altered phospholipid metabolism in a temperature-sensitive mutant of Escherichia coli, CR34T46 Biochimica Et Biophysica Acta (Bba)/Lipids and Lipid Metabolism. 270: 504-512. PMID 4559905 DOI: 10.1016/0005-2760(72)90115-4  0.529
1972 Cronan JE, Vagelos PR. Metabolism and function of the membrane phospholipids of Escherichia coli Bba - Reviews On Biomembranes. 265: 25-60. PMID 4552305 DOI: 10.1016/0304-4157(72)90018-4  0.48
1972 Mavis RD, Vagelos PR. The effect of phospholipid fatty acid composition in membranous enzymes in Escherichia coli. Journal of Biological Chemistry. 247: 652-659. PMID 4550756  0.393
1972 Mavis RD, Bell RM, Vagelos PR. Effect of phospholipase C hydrolysis of membrane phospholipids on membranous enzymes. Journal of Biological Chemistry. 247: 2835-2841. PMID 4337103  0.459
1972 Alberts AW, Vagelos PR. 2 Acyl-CoA Carboxylases Enzymes. 6: 37-82. DOI: 10.1016/S1874-6047(08)60037-2  0.33
1971 Cronan JE, Vagelos PR. Abortive infection by phage T4 under conditions of defective host membrane lipid biosynthesis Virology. 43: 412-421. PMID 5543829 DOI: 10.1016/0042-6822(71)90313-8  0.469
1971 Bell RM, Mavis RD, Osborn MJ, Vagelos PR. Enzymes of phospholipid metabolism: localization in the cytoplasmic and outer membrane of the cell envelope of Escherichia coli and Salmonella typhimurium. Biochimica Et Biophysica Acta. 249: 628-35. PMID 5002558 DOI: 10.1016/0005-2736(71)90144-1  0.547
1971 Alberts AW, Gordon SG, Vagelos PR. Acetyl CoA carboxylase: the purified transcarboxylase component. Proceedings of the National Academy of Sciences of the United States of America. 68: 1259-1263. PMID 4942182 DOI: 10.1073/Pnas.68.6.1259  0.361
1971 Fall RR, Nervi AM, Alberts AW, Vagelos PR. Acetyl CoA carboxylase: isolation and characterization of native biotin carboxyl carrier protein. Proceedings of the National Academy of Sciences of the United States of America. 68: 1512-1515. PMID 4934522 DOI: 10.1073/Pnas.68.7.1512  0.315
1971 Nervi AM, Alberts AW, Vagelos PR. Acetyl CoA carboxylase. III. Purification and properties of a biotin carboxyl carrier protein Archives of Biochemistry and Biophysics. 143: 401-411. PMID 4934179 DOI: 10.1016/0003-9861(71)90227-X  0.349
1971 Hancock WS, Prescott DJ, Nulty WL, Weintraub J, Vagelos PR, Marshall GR. The synthesis of a protein with acyl carrier protein activity [15] Journal of the American Chemical Society. 93: 1799-1800. PMID 4927590 DOI: 10.1021/Ja00736A048  0.503
1971 Vagelos PR. Regulation of Fatty Acid Biosynthesis Current Topics in Cellular Regulation. 4: 119-166. DOI: 10.1016/B978-0-12-152804-1.50010-6  0.492
1970 Greenspan MD, Birge CH, Powell G, Hancock WS, Vagelos PR. Enzyme specificity as a factor in regulation of fatty acid chain length in Escherichia coli. Science (New York, N.Y.). 170: 1203-4. PMID 4920654 DOI: 10.1126/Science.170.3963.1203  0.663
1970 Van Den Bosch H, Williamson JR, Vagelos PR. Localization of acyl carrier protein in escherichia coli Nature. 228: 338-341. PMID 4919772 DOI: 10.1038/228338A0  0.38
1970 Cronan JE, Ray TK, Vagelos PR. Selection and characterization of an E. coli mutant defective in membrane lipid biosynthesis. Proceedings of the National Academy of Sciences of the United States of America. 65: 737-44. PMID 4910856 DOI: 10.1073/Pnas.65.3.737  0.447
1970 Van Den Bosch H, Vagelos PR. Fatty acyl-coA and fatty acyl-acyl carrier protein as acyl donors in the synthesis of lysophosphatidate and phosphatidate in escherichia coli Biochimica Et Biophysica Acta (Bba)/Lipids and Lipid Metabolism. 218: 233-248. DOI: 10.1016/0005-2760(70)90142-6  0.499
1969 Cronan JE, Birge CH, Vagelos PR. Evidence for two genes specifically involved in unsaturated fatty acid biosynthesis in Escherichia coli. Journal of Bacteriology. 100: 601-604. PMID 4901354 DOI: 10.1128/Jb.100.2.601-604.1969  0.586
1969 Vagelos PR, Larrabee AR. [14] Acyl carrier protein hydrolase Methods in Enzymology. 14: 81-83. DOI: 10.1016/S0076-6879(69)14016-1  0.369
1968 Silbert DF, Ruch F, Vagelos PR. Fatty acid replacements in a fatty acid auxotroph of Escherichia coli. Journal of Bacteriology. 95: 1658-1665. PMID 4870280 DOI: 10.1128/Jb.95.5.1658-1665.1968  0.736
1967 Silbert DF, Vagelos PR. Fatty acid mutant of E. coli lacking a beta-hydroxydecanoyl thioester dehydrase. Proceedings of the National Academy of Sciences of the United States of America. 58: 1579-86. PMID 4867667  0.721
1967 Majerus PW, Vagelos PR. Fatty acid biosynthesis and the role of the acyl carrier protein. Advances in Lipid Research. 5: 1-33. PMID 4866072  0.636
1967 Birge CH, Silbert DF, Vagelos PR. A beta-hydroxydecanoyl-ACP dehydrase specific for saturated fatty acid biosynthesis in E. coli. Biochemical and Biophysical Research Communications. 29: 808-14. PMID 4294857 DOI: 10.1016/0006-291X(67)90291-4  0.725
1967 Birge CH, Silbert DF, Vagelos PR. A β-hydroxydecanoyl-ACP dehydrase specific for saturated fatty acid biosynthesis in E.,coli Biochemical and Biophysical Research Communications. 29: 808-814.  0.722
1966 Rudney H, Stewart PR, Majerus PW, Vagelos PR. The biosynthesis of beta-hydroxy-beta-methylglutaryl coenzyme A in yeast. V. The role of acyl carrier protein. The Journal of Biological Chemistry. 241: 1226-8. PMID 5933879  0.47
1966 Vagelos PR, Majerus PW, Alberts AW, Larrabee AR, Ailhaud GP. Structure and function of the acyl carrier protein. Federation Proceedings. 25: 1485-94. PMID 5332188  0.476
1965 MAJERUS PW, ALBERTS AW, VAGELOS PR. ACYL CARRIER PROTEIN. IV. THE IDENTIFICATION OF 4'-PHOSPHOPANTETHEINE AS THE PROSTHETIC GROUP OF THE ACYL CARRIER PROTEIN. Proceedings of the National Academy of Sciences of the United States of America. 53: 410-7. PMID 14294075  0.503
1965 MAJERUS PW, ALBERTS AW, VAGELOS PR. ACYL CARRIER PROTEIN. 3. AN ENOYL HYDRASE SPECIFIC FOR ACYL CARRIER PROTEIN THIOESTERS. The Journal of Biological Chemistry. 240: 618-21. PMID 14275113  0.517
1965 Majerus PW, Alberts AW, Vagelos PR. Acyl carrier protein. VII. The primary structure of the substrate-binding site. The Journal of Biological Chemistry. 240: 4723-6. PMID 5321310  0.463
1965 Vagelos PR, Alberts AW, Majerus PW. The mechanism of fatty acid biosynthesis and the involvement of an acyl carrier protein. Annals of the New York Academy of Sciences. 131: 177-88. PMID 5216961 DOI: 10.1111/J.1749-6632.1965.Tb34787.X  0.629
1965 Larrabee AR, McDaniel EG, Bakerman HA, Vagelos PR. Acyl carrier protein. V. Identification of 4'-phosphopantetheine bound to a mammalian fatty acid synthetase preparation. Proceedings of the National Academy of Sciences of the United States of America. 54: 267-73. PMID 5216362  0.408
1965 Alberts AW, Majerus PW, Vagelos PR. Acyl carrier protein. VI. Purification and properties of β-ketoacyl acyl carrier protein synthetase Biochemistry. 4: 2265-2274. DOI: 10.1021/Bi00887A002  0.557
1964 ALBERTS AW, MAJERUS PW, TALAMO B, VAGELOS PR. ACYL-CARRIER PROTEIN. II. INTERMEDIARY REACTIONS OF FATTY ACID SYNTHESIS. Biochemistry. 3: 1563-71. PMID 14232033 DOI: 10.1021/Bi00898A030  0.63
1964 MAJERUS PW, ALBERTS AW, VAGELOS PR. THE ACYL CARRIER PROTEIN OF FATTY ACID SYNTHESIS: PURIFICATION, PHYSICAL PROPERTIES, AND SUBSTRATE BINDING SITE. Proceedings of the National Academy of Sciences of the United States of America. 51: 1231-8. PMID 14215649  0.582
1963 GOLDMAN P, ALBERTS AW, VAGELOS PR. THE CONDENSATION REACTION OF FATTY ACID SYNTHESIS.III. IDENTIFICATION OF THE PROTEIN-BOUND PRODUCT OF THE REACTION AND ITS CONVERSION TO LONG CHAIN FATTY ACIDS. The Journal of Biological Chemistry. 238: 3579-83. PMID 14109189  0.359
1963 ALBERTS AW, GOLDMAN P, VAGELOS PR. The condensation reaction of fatty acid synthesis. I. Separation and properties of the enzymes The Journal of Biological Chemistry. 238: 557-565. PMID 14011744  0.335
1963 GOLDMAN P, ALBERTS AW, VAGELOS PR. The condensation reaction of fatty acid biosynthesis. II. Requirement of the enzymes of the condensation reaction for fatty acid synthesis The Journal of Biological Chemistry. 238: 1255-1261. PMID 13948777  0.349
1962 MARTIN DB, VAGELOS PR. The mechanism of tricarboxylic acid cycle regulation of fatty acid The Journal of Biological Chemistry. 237: 1787-1792. PMID 14470343  0.356
1962 Martin DB, Vagelos PR. Mechanism of tricarboxylic acid cycle regulation of fatty acid synthesis Biochemical and Biophysical Research Communications. 7: 101-106. PMID 14470342  0.367
1962 Goldman P, Vagelos PR. The formation of enzyme-bound acetoacetate and its converstion to long chain fatty acids Biochemical and Biophysical Research Communications. 7: 414-418. PMID 13899832  0.319
1961 Martin DB, Vagelos PR. Evidence against free butyryl-CoA as an intermediate in long chain fatty acid biosynthesis Biochemical and Biophysical Research Communications. 5: 16-21. PMID 13767324  0.332
1961 MARTIN DB, HORNING MG, VAGELOS PR. Fatty acid synthesis in adipose tissue. I. Purification and properties of a long chain fatty acid-synthesizing system The Journal of Biological Chemistry. 236: 663-668. PMID 13767323  0.351
1961 HORNING MG, MARTIN DB, KARMEN A, VAGELOS PR. Fatty acid synthesis in adipose tissue. II. Enzymatic synthesis of branched chain and odd-numbered fatty acids The Journal of Biological Chemistry. 236: 669-672. PMID 13715907  0.351
1960 VAGELOS PR. Propionic acid metabolism. IV. Synthesis of malonyl coenzyme A The Journal of Biological Chemistry. 235: 346-350. PMID 13840646  0.329
1960 Horning MG, Martin DB, Karmen A, Vagelos PR. Synthesis of branched-chain and odd-numbered fatty acids from malonyl-CoA Biochemical and Biophysical Research Communications. 3: 101-106.  0.346
1959 VAGELOS PR, EARL JM, STADTMAN ER. Propionic acid metabolism. II. Enzymatic synthesis of lactyl pantethine. The Journal of Biological Chemistry. 234: 765-9. PMID 13654259  0.633
1959 VAGELOS PR, EARL JM, STADTMAN ER. Propionic acid metabolism. I. The purification and properties of acrylyl coenzme A aminase. The Journal of Biological Chemistry. 234: 490-7. PMID 13641247  0.643
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