| Year |
Citation |
Score |
| 2011 |
Lindemann L, Jaeschke G, Michalon A, Vieira E, Honer M, Spooren W, Porter R, Hartung T, Kolczewski S, Büttelmann B, Flament C, Diener C, Fischer C, Gatti S, Prinssen EP, et al. CTEP: a novel, potent, long-acting, and orally bioavailable metabotropic glutamate receptor 5 inhibitor. The Journal of Pharmacology and Experimental Therapeutics. 339: 474-86. PMID 21849627 DOI: 10.1124/jpet.111.185660 |
0.35 |
|
| 2011 |
Kratochwil NA, Gatti-McArthur S, Hoener MC, Lindemann L, Christ AD, Green LG, Guba W, Martin RE, Malherbe P, Porter RH, Slack JP, Winnig M, Dehmlow H, Grether U, Hertel C, et al. G protein-coupled receptor transmembrane binding pockets and their applications in GPCR research and drug discovery: a survey. Current Topics in Medicinal Chemistry. 11: 1902-24. PMID 21470172 DOI: 10.2174/156802611796391267 |
0.411 |
|
| 2011 |
Wallace TL, Porter R, Neveu E, Bertrand D. Effects of RG3487 at the α7β2 nicotinic acetylcholine receptor expressed in Xenopus oocytes Biochemical Pharmacology. 82: 1026-1027. DOI: 10.1016/J.Bcp.2011.07.012 |
0.331 |
|
| 2006 |
Malherbe P, Kratochwil N, Mühlemann A, Zenner MT, Fischer C, Stahl M, Gerber PR, Jaeschke G, Porter RH. Comparison of the binding pockets of two chemically unrelated allosteric antagonists of the mGlu5 receptor and identification of crucial residues involved in the inverse agonism of MPEP. Journal of Neurochemistry. 98: 601-15. PMID 16805850 DOI: 10.1111/J.1471-4159.2006.03886.X |
0.437 |
|
| 2006 |
Mühlemann A, Ward NA, Kratochwil N, Diener C, Fischer C, Stucki A, Jaeschke G, Malherbe P, Porter RH. Determination of key amino acids implicated in the actions of allosteric modulation by 3,3'-difluorobenzaldazine on rat mGlu5 receptors. European Journal of Pharmacology. 529: 95-104. PMID 16352303 DOI: 10.1016/j.ejphar.2005.11.008 |
0.348 |
|
| 2005 |
Ballard TM, Woolley ML, Prinssen E, Huwyler J, Porter R, Spooren W. The effect of the mGlu5 receptor antagonist MPEP in rodent tests of anxiety and cognition: A comparison Psychopharmacology. 179: 218-229. PMID 15739074 DOI: 10.1007/s00213-005-2211-9 |
0.301 |
|
| 2003 |
Malherbe P, Kratochwil N, Zenner MT, Piussi J, Diener C, Kratzeisen C, Fischer C, Porter RH. Mutational analysis and molecular modeling of the binding pocket of the metabotropic glutamate 5 receptor negative modulator 2-methyl-6-(phenylethynyl)-pyridine. Molecular Pharmacology. 64: 823-32. PMID 14500738 DOI: 10.1124/mol.64.4.823 |
0.371 |
|
| 2001 |
Quirk K, Lawrence A, Jones J, Misra A, Harvey V, Lamb H, Revell D, Porter RH, Knight AR. Characterisation of agonist binding on human 5-HT2C receptor isoforms. European Journal of Pharmacology. 419: 107-12. PMID 11426831 DOI: 10.1016/S0014-2999(01)00943-8 |
0.387 |
|
| 2000 |
Betarbet R, Porter RH, Greenamyre JT. GluR1 glutamate receptor subunit is regulated differentially in the primate basal ganglia following nigrostriatal dopamine denervation. Journal of Neurochemistry. 74: 1166-74. PMID 10693949 DOI: 10.1046/J.1471-4159.2000.741166.X |
0.607 |
|
| 1999 |
Porter RH, Benwell KR, Lamb H, Malcolm CS, Allen NH, Revell DF, Adams DR, Sheardown MJ. Functional characterization of agonists at recombinant human 5-HT2A, 5-HT2B and 5-HT2C receptors in CHO-K1 cells. British Journal of Pharmacology. 128: 13-20. PMID 10498829 DOI: 10.1038/Sj.Bjp.0702751 |
0.356 |
|
| 1996 |
Eastwood SL, Porter RH, Harrison PJ. The effect of chronic haloperidol treatment on glutamate receptor subunit (GluR1, GluR2, KA1, KA2, NR1) mRNAs and glutamate binding protein mRNA in rat forebrain. Neuroscience Letters. 212: 163-6. PMID 8843098 DOI: 10.1016/0304-3940(96)12801-9 |
0.325 |
|
| 1996 |
Blandini F, Porter RH, Greenamyre JT. Glutamate and Parkinson's disease. Molecular Neurobiology. 12: 73-94. PMID 8732541 DOI: 10.1007/Bf02740748 |
0.579 |
|
| 1996 |
Greene JG, Porter RH, Greenamyre JT. ARL-15896, a novel N-methyl-D-aspartate receptor ion channel antagonist: neuroprotection against mitochondrial metabolic toxicity and regional pharmacology. Experimental Neurology. 137: 66-72. PMID 8566213 DOI: 10.1006/Exnr.1996.0007 |
0.711 |
|
| 1995 |
Blandini F, Porter RH, Greenamyre JT. Autoradiographic study of mitochondrial complex I and glutamate receptors in the basal ganglia of rats after unilateral subthalamic lesion. Neuroscience Letters. 186: 99-102. PMID 7777208 DOI: 10.1016/0304-3940(95)11292-5 |
0.669 |
|
| 1995 |
Porter RH, Greenamyre JT. Regional variations in the pharmacology of NMDA receptor channel blockers: implications for therapeutic potential. Journal of Neurochemistry. 64: 614-23. PMID 7530291 DOI: 10.1046/J.1471-4159.1995.64020614.X |
0.619 |
|
| 1994 |
Porter RH, Greenamyre JT. Inhibition of autoradiographic MK-801 binding by an endogenous factor. Neuroscience Letters. 169: 105-8. PMID 8047262 DOI: 10.1016/0304-3940(94)90367-0 |
0.577 |
|
| 1994 |
Porter RH, Greene JG, Higgins DS, Greenamyre JT. Polysynaptic regulation of glutamate receptors and mitochondrial enzyme activities in the basal ganglia of rats with unilateral dopamine depletion. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 14: 7192-9. PMID 7965108 DOI: 10.1523/Jneurosci.14-11-07192.1994 |
0.716 |
|
| 1994 |
Porter RH, Greenamyre JT. Regional variations in the pharmacology of AMPA receptors as revealed by receptor autoradiography. Brain Research. 664: 202-6. PMID 7534602 |
0.6 |
|
| 1994 |
Greenamyre JT, Porter RH. Anatomy and physiology of glutamate in the CNS. Neurology. 44: S7-13. PMID 7526272 |
0.558 |
|
| 1993 |
Porter RH, Roberts PJ. Glutamate metabotropic receptor activation in neonatal rat cerebral cortex by sulphur-containing excitatory amino acids. Neuroscience Letters. 154: 78-80. PMID 8395670 DOI: 10.1016/0304-3940(93)90175-K |
0.405 |
|
| 1993 |
Eaton SA, Jane DE, Jones PL, Porter RH, Pook PC, Sunter DC, Udvarhelyi PM, Roberts PJ, Salt TE, Watkins JC. Competitive antagonism at metabotropic glutamate receptors by (S)-4-carboxyphenylglycine and (RS)-alpha-methyl-4-carboxyphenylglycine. European Journal of Pharmacology. 244: 195-7. PMID 8381746 DOI: 10.1016/0922-4106(93)90028-8 |
0.391 |
|
| 1993 |
Greene JG, Porter RH, Eller RV, Greenamyre JT. Inhibition of succinate dehydrogenase by malonic acid produces an "excitotoxic" lesion in rat striatum. Journal of Neurochemistry. 61: 1151-4. PMID 8360680 DOI: 10.1111/J.1471-4159.1993.Tb03634.X |
0.697 |
|
| 1993 |
Porter RH, Roberts PJ, Briggs RS. NMDA receptor status in elderly normal individuals and those with Alzheimer's disease. Annals of the New York Academy of Sciences. 695: 50-3. PMID 8239312 DOI: 10.1111/J.1749-6632.1993.Tb23026.X |
0.454 |
|
| 1993 |
Birse EF, Eaton SA, Jane DE, Jones PL, Porter RH, Pook PC, Sunter DC, Udvarhelyi PM, Wharton B, Roberts PJ. Phenylglycine derivatives as new pharmacological tools for investigating the role of metabotropic glutamate receptors in the central nervous system. Neuroscience. 52: 481-8. PMID 7680790 DOI: 10.1016/0306-4522(93)90400-A |
0.483 |
|
| 1993 |
Sandhu FA, Porter RH, Eller RV, Zain SB, Salim M, Greenamyre JT. NMDA and AMPA receptors in transgenic mice expressing human beta-amyloid protein. Journal of Neurochemistry. 61: 2286-9. PMID 7504089 DOI: 10.1111/J.1471-4159.1993.Tb07471.X |
0.552 |
|
| 1992 |
Porter RH, Briggs RS, Roberts PJ. L-aspartate-beta-hydroxamate exhibits mixed agonist/antagonist activity at the glutamate metabotropic receptor in rat neonatal cerebrocortial slices. Neuroscience Letters. 144: 87-9. PMID 1436717 DOI: 10.1016/0304-3940(92)90722-J |
0.405 |
|
| 1992 |
Porter RH, Briggs RS, Roberts PJ. Modulation of [3H]3-((+-)-2-carboxypiperazin-4-yl)propyl-1-phosphonic acid ([3H]CPP) binding by ligands acting at the glycine and the polyamine sites of the rat brain NMDA receptor complex. European Journal of Pharmacology. 227: 83-8. PMID 1426025 DOI: 10.1016/0922-4106(92)90146-M |
0.47 |
|
| 1992 |
Porter RH, Cowburn RF, Alasuzoff I, Briggs RS, Roberts PJ. Heterogeneity of NMDA receptors labelled with [3H]3-((+-)-2-carboxypiperazin-4-yl) propyl-1-phosphonic acid ([3H]CPP): receptor status in Alzheimer's disease brains. European Journal of Pharmacology. 225: 195-201. PMID 1387617 DOI: 10.1016/0922-4106(92)90020-V |
0.466 |
|
| 1992 |
Porter RH, Roberts PJ, Jane DE, Watkins JC. (S)-homoquisqualate: a potent agonist at the glutamate metabotropic receptor. British Journal of Pharmacology. 106: 509-10. PMID 1324071 DOI: 10.1111/J.1476-5381.1992.Tb14366.X |
0.431 |
|
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