| Year |
Citation |
Score |
| 2021 |
Evans RH, Watkins JC. Team Evans and Watkins: Excitatory Amino Acid Research at Bristol 1973-1981. Neuropharmacology. 108768. PMID 34454911 DOI: 10.1016/j.neuropharm.2021.108768 |
0.393 |
|
| 2021 |
Watkins JC, Evans RH, Bayés À, Booker SA, Gibb A, Mabb AM, Mayer M, Mellor JR, Molnár E, Niu L, Ortega A, Pankratov Y, Ramos-Vicente D, Rodríguez-Campuzano A, Rodríguez-Moreno A, et al. 21 Century Excitatory Amino Acid Research: a Q &A with Jeff Watkins and Dick Evans. Neuropharmacology. 108743. PMID 34363811 DOI: 10.1016/j.neuropharm.2021.108743 |
0.337 |
|
| 2018 |
Lodge D, Watkins JC, Bortolotto ZA, Jane DE, Volianskis A. The 1980s: D-AP5, LTP and a Decade of NMDA Receptor Discoveries. Neurochemical Research. PMID 30284673 DOI: 10.1007/S11064-018-2640-6 |
0.677 |
|
| 2012 |
Jane DE, Olverman HJ, Watkins JC. Agonists and competitive antagonists: Structure-activity and molecular modelling studies The Nmda Receptor. DOI: 10.1093/acprof:oso/9780192625021.003.0002 |
0.536 |
|
| 2012 |
Watkins JC. The NMDA receptor concept: Origins and development The Nmda Receptor. DOI: 10.1093/acprof:oso/9780192625021.003.0001 |
0.324 |
|
| 2012 |
Collingridge GL, Watkins JC. The NMDA Receptor The Nmda Receptor. 1-518. DOI: 10.1093/acprof:oso/9780192625021.001.0001 |
0.337 |
|
| 2006 |
Watkins JC, Jane DE. The glutamate story. British Journal of Pharmacology. 147: S100-8. PMID 16402093 DOI: 10.1038/Sj.Bjp.0706444 |
0.692 |
|
| 2000 |
Watkins JC. l-glutamate as a central neurotransmitter: looking back. Biochemical Society Transactions. 28: 297-309. PMID 10961913 |
0.332 |
|
| 1998 |
Brown JC, Tse HW, Skifter DA, Christie JM, Andaloro VJ, Kemp MC, Watkins JC, Jane DE, Monaghan DT. [3H]homoquinolinate binds to a subpopulation of NMDA receptors and to a novel binding site. Journal of Neurochemistry. 71: 1464-70. PMID 9751179 DOI: 10.1046/J.1471-4159.1998.71041464.X |
0.639 |
|
| 1997 |
Wilson C, Howard JA, Jane DE, Sunter DC, Watkins JC. Absolute configuration of (+)-alpha-methyl-4-carboxyphenylglycine (MCPG), a metabotropic glutamate receptor antagonist. Acta Crystallographica. Section C, Crystal Structure Communications. 53: 909-11. PMID 9241811 DOI: 10.1107/S0108270197003223 |
0.665 |
|
| 1997 |
Thoreson WB, Gottesman J, Jane DE, Tse HW, Watkins JC, Miller RF. Two phenylglycine derivatives antagonize responses to L-AP4 in ON bipolar cells of the amphibian retina. Neuropharmacology. 36: 13-20. PMID 9144637 DOI: 10.1016/S0028-3908(96)00164-5 |
0.665 |
|
| 1997 |
Curtis DR, Phillis JW, Watkins JC. Actions of amino-acids on the isolated hemisected spinal cord of the toad. 1961. British Journal of Pharmacology. 120: 204-25; discussion 2. PMID 9142407 |
0.588 |
|
| 1997 |
Wilson C, Howard JAK, Jane DE, Sunter DC, Watkins JC. Absolute configuration of (+)-α-methyl-4-carboxyphenylglycine (MCPG), a metabotropic glutamate receptor antagonist Acta Crystallographica Section C: Crystal Structure Communications. 53: 909-911. |
0.621 |
|
| 1996 |
Jane DE, Thomas NK, Tse HW, Watkins JC. Potent antagonists at the L-AP4- and (1S,3S)-ACPD-sensitive presynaptic metabotropic glutamate receptors in the neonatal rat spinal cord. Neuropharmacology. 35: 1029-35. PMID 9121605 DOI: 10.1016/S0028-3908(96)00048-2 |
0.712 |
|
| 1996 |
Jane DE, Chalmers DJ, Howard JA, Kilpatrick IC, Sunter DC, Thompson GA, Udvarhelyi PM, Wilson C, Watkins JC. Diastereoselective synthesis of all four isomers of 3-(4-chlorophenyl) glutamic acid: identification of the isomers responsible for the potentiation of L-homocysteic acid-evoked depolarizations in neonatal rat motoneurons. Journal of Medicinal Chemistry. 39: 4738-43. PMID 8941386 DOI: 10.1021/Jm960382C |
0.646 |
|
| 1996 |
Thomas NK, Jane DE, Tse HW, Watkins JC. alpha-Methyl derivatives of serine-O-phosphate as novel, selective competitive metabotropic glutamate receptor antagonists. Neuropharmacology. 35: 637-42. PMID 8887973 DOI: 10.1016/0028-3908(96)84635-1 |
0.696 |
|
| 1996 |
Sekiyama N, Hayashi Y, Nakanishi S, Jane DE, Tse HW, Birse EF, Watkins JC. Structure-activity relationships of new agonists and antagonists of different metabotropic glutamate receptor subtypes. British Journal of Pharmacology. 117: 1493-503. PMID 8730745 DOI: 10.1111/J.1476-5381.1996.Tb15312.X |
0.69 |
|
| 1996 |
Bushell TJ, Jane DE, Tse HW, Watkins JC, Garthwaite J, Collingridge GL. Pharmacological antagonism of the actions of group II and III mGluR agonists in the lateral perforant path of rat hippocampal slices. British Journal of Pharmacology. 117: 1457-62. PMID 8730739 DOI: 10.1111/J.1476-5381.1996.Tb15306.X |
0.685 |
|
| 1995 |
Chalmers DJ, Jane DE, Sunter DC, Thompson GA, Udvarhelyi PM, Kilpatrick IC, Watkins JC. Differential actions of 3-(4-chlorophenyl) glutamic acid stereoisomers and L-trans-pyrrolidine-2,4-dicarboxylic acid upon L-homocysteic acid- and L-glutamic acid-induced responses from rat spinal motoneurones. Neuropharmacology. 34: 1589-95. PMID 8788956 DOI: 10.1016/0028-3908(95)00124-7 |
0.681 |
|
| 1995 |
Bedingfield JS, Kemp MC, Jane DE, Tse HW, Roberts PJ, Watkins JC. Structure-activity relationships for a series of phenylglycine derivatives acting at metabotropic glutamate receptors (mGluRs). British Journal of Pharmacology. 116: 3323-9. PMID 8719814 DOI: 10.1111/J.1476-5381.1995.Tb15142.X |
0.683 |
|
| 1995 |
Attwell PJ, Kaura S, Sigala G, Bradford HF, Croucher MJ, Jane DE, Watkins JC. Blockade of both epileptogenesis and glutamate release by (1S,3S)-ACPD, a presynaptic glutamate receptor agonist. Brain Research. 698: 155-62. PMID 8581475 DOI: 10.1016/0006-8993(95)00886-U |
0.665 |
|
| 1995 |
Vignes M, Clarke VR, Davies CH, Chambers A, Jane DE, Watkins JC, Collingridge GL. Pharmacological evidence for an involvement of group II and group III mGluRs in the presynaptic regulation of excitatory synaptic responses in the CA1 region of rat hippocampal slices. Neuropharmacology. 34: 973-82. PMID 8532178 DOI: 10.1016/0028-3908(95)00093-L |
0.647 |
|
| 1995 |
Jane DE, Pittaway K, Sunter DC, Thomas NK, Watkins JC. New phenylglycine derivatives with potent and selective antagonist activity at presynaptic glutamate receptors in neonatal rat spinal cord. Neuropharmacology. 34: 851-6. PMID 8532166 DOI: 10.1016/0028-3908(95)00063-C |
0.714 |
|
| 1995 |
Bushell TJ, Jane DE, Tse HW, Watkins JC, Davies CH, Garthwaite J, Collingridge GL. Antagonism of the synaptic depressant actions of L-AP4 in the lateral perforant path by MAP4. Neuropharmacology. 34: 239-41. PMID 7617150 DOI: 10.1016/0028-3908(95)00012-U |
0.633 |
|
| 1994 |
Hayashi Y, Sekiyama N, Nakanishi S, Jane DE, Sunter DC, Birse EF, Udvarhelyi PM, Watkins JC. Analysis of agonist and antagonist activities of phenylglycine derivatives for different cloned metabotropic glutamate receptor subtypes. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 14: 3370-7. PMID 8182479 |
0.66 |
|
| 1994 |
Kemp M, Roberts P, Pook P, Jane D, Jones A, Jones P, Sunter D, Udvarhelyi P, Watkins J. Antagonism of presynaptically mediated depressant responses and cyclic AMP-coupled metabotropic glutamate receptors European Journal of Pharmacology: Molecular Pharmacology. 266: 187-192. PMID 8157072 DOI: 10.1016/0922-4106(94)90109-0 |
0.694 |
|
| 1994 |
Gaoni Y, Chapman AG, Parvez N, Pook PC, Jane DE, Watkins JC. Synthesis, NMDA receptor antagonist activity, and anticonvulsant action of 1-aminocyclobutanecarboxylic acid derivatives. Journal of Medicinal Chemistry. 37: 4288-96. PMID 7996540 DOI: 10.1021/Jm00051A005 |
0.697 |
|
| 1994 |
Watkins JC, Collingridge GL. Phenylglycine derivatives as antagonists of metabotropic glutamate receptors Trends in Pharmacological Sciences. 15: 333-342. PMID 7992387 DOI: 10.1016/0165-6147(94)90028-0 |
0.488 |
|
| 1994 |
Jane DE, Jones PL, Pook PC, Tse HW, Watkins JC. Actions of two new antagonists showing selectivity for different sub-types of metabotropic glutamate receptor in the neonatal rat spinal cord. British Journal of Pharmacology. 112: 809-16. PMID 7921606 DOI: 10.1111/J.1476-5381.1994.Tb13151.X |
0.712 |
|
| 1994 |
Wong LA, Mayer ML, Jane DE, Watkins JC. Willardiines differentiate agonist binding sites for kainate- versus AMPA-preferring glutamate receptors in DRG and hippocampal neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 14: 3881-97. PMID 7515954 |
0.628 |
|
| 1994 |
Hayashi Y, Sekiyama N, Nakanishi S, Jane D, Sunter D, Birse E, Udvarhelyi P, Watkins J. Analysis of agonist and antagonist activities of phenylglycine derivatives for different cloned metabotropic glutamate receptor subtypes The Journal of Neuroscience. 14: 3370-3377. DOI: 10.1523/Jneurosci.14-05-03370.1994 |
0.66 |
|
| 1993 |
Bashir ZI, Bortolotto ZA, Davies CH, Berretta N, Irving AJ, Seal AJ, Henley JM, Jane DE, Watkins JC, Collingridge GL. Induction of LTP in the hippocampus needs synaptic activation of glutamate metabotropic receptors. Nature. 363: 347-50. PMID 8388549 DOI: 10.1038/363347A0 |
0.652 |
|
| 1993 |
Eaton SA, Jane DE, Jones PL, Porter RH, Pook PC, Sunter DC, Udvarhelyi PM, Roberts PJ, Salt TE, Watkins JC. Competitive antagonism at metabotropic glutamate receptors by (S)-4-carboxyphenylglycine and (RS)-alpha-methyl-4-carboxyphenylglycine. European Journal of Pharmacology. 244: 195-7. PMID 8381746 DOI: 10.1016/0922-4106(93)90028-8 |
0.698 |
|
| 1993 |
Eaton SA, Birse EF, Wharton B, Sunter DC, Udvarhelyi PM, Watkins JC, Salt TE. Mediation of thalamic sensory responses in vivo by ACPD-activated excitatory amino acid receptors. The European Journal of Neuroscience. 5: 186-9. PMID 8261098 DOI: 10.1111/J.1460-9568.1993.Tb00484.X |
0.483 |
|
| 1993 |
Bashir ZI, Jane DE, Sunter DC, Watkins JC, Collingridge GL. Metabotropic glutamate receptors contribute to the induction of long-term depression in the CA1 region of the hippocampus. European Journal of Pharmacology. 239: 265-6. PMID 8223907 DOI: 10.1016/0014-2999(93)91009-C |
0.604 |
|
| 1993 |
Pook P, Brugger F, Hawkins NS, Clark KC, Watkins JC, Evans RH. A comparison of the actions of agonists and antagonists at non-NMDA receptors of C fibres and motoneurones of the immature rat spinal cord in vitro. British Journal of Pharmacology. 108: 179-84. PMID 8094024 DOI: 10.1111/J.1476-5381.1993.Tb13459.X |
0.518 |
|
| 1993 |
Jane DE, Jones PL, Pook PC, Salt TE, Sunter DC, Watkins JC. Stereospecific antagonism by (+)-alpha-methyl-4-carboxyphenylglycine (MCPG) of (1S,3R)-ACPD-induced effects in neonatal rat motoneurones and rat thalamic neurones. Neuropharmacology. 32: 725-7. PMID 7689710 DOI: 10.1016/0028-3908(93)90088-K |
0.675 |
|
| 1993 |
Glaum SR, Sunter DC, Udvarhelyi PM, Watkins JC, Miller RJ. The actions of phenylglycine derived metabotropic glutamate receptor antagonists on multiple (1S,3R)-ACPD responses in the rat nucleus of the tractus solitarius. Neuropharmacology. 32: 1419-25. PMID 7512236 DOI: 10.1016/0028-3908(93)90039-6 |
0.48 |
|
| 1993 |
Hayashi Y, Sekiyama N, Nakanishi S, Jane DE, Sunter DC, Birse EF, Udvarhelyi PM, Watkins JC. 314 Analysis of agonist and antagonist activities of phenylglycine derivatives for metabotropic glutamate receptors Neuroscience Research Supplements. 18: S41. DOI: 10.1016/S0921-8696(05)80784-4 |
0.672 |
|
| 1992 |
Pook PC, Sunter DC, Udvarhelyi PM, Watkins JC. Evidence for presynaptic depression of monosynaptic excitation in neonatal rat motoneurones by (1S,3S)- and (1S,3R)-ACPD. Experimental Physiology. 77: 529-32. PMID 1632963 |
0.364 |
|
| 1992 |
Patneau DK, Mayer ML, Jane DE, Watkins JC. Activation and desensitization of AMPA/kainate receptors by novel derivatives of willardiine. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 12: 595-606. PMID 1371315 DOI: 10.1523/Jneurosci.12-02-00595.1992 |
0.652 |
|
| 1992 |
Porter RH, Roberts PJ, Jane DE, Watkins JC. (S)-homoquisqualate: a potent agonist at the glutamate metabotropic receptor. British Journal of Pharmacology. 106: 509-10. PMID 1324071 DOI: 10.1111/J.1476-5381.1992.Tb14366.X |
0.701 |
|
| 1991 |
Watkins JC. Some chemical highlights in the development of excitatory amino acid pharmacology. Canadian Journal of Physiology and Pharmacology. 69: 1064-75. PMID 1954563 |
0.417 |
|
| 1990 |
Irving AJ, Schofield JG, Watkins JC, Sunter DC, Collingridge GL. 1S,3R-ACPD stimulates and L-AP3 blocks Ca2+ mobilization in rat cerebellar neurons. European Journal of Pharmacology. 186: 363-5. PMID 2289537 DOI: 10.1016/0014-2999(90)90462-F |
0.326 |
|
| 1990 |
Watkins JC, Krogsgaard-Larsen P, Honoré T. Structure-activity relationships in the development of excitatory amino acid receptor agonists and competitive antagonists. Trends in Pharmacological Sciences. 11: 25-33. PMID 2155495 DOI: 10.1016/0165-6147(90)90038-A |
0.432 |
|
| 1990 |
Udvarhelyi PM, Sunter DC, Watkins JC. Direct separation of amino acid enantiomers using a chiral crown ether stationary phase. Application to 2-amino-omega-phosphonoalkanoic acids. Journal of Chromatography. 519: 69-74. PMID 2150201 DOI: 10.1016/0021-9673(90)85135-I |
0.333 |
|
| 1990 |
Watkins JC, Pook PC, Sunter DC, Davies J, Honore T. Experiments with kainate and quisqualate agonists and antagonists in relation to the sub-classification of 'non-NMDA' receptors. Advances in Experimental Medicine and Biology. 268: 49-55. PMID 1963751 |
0.418 |
|
| 1989 |
Honoré T, Drejer J, Nielsen EO, Watkins JC, Olverman HJ, Nielsen M. Molecular target size analyses of the NMDA-receptor complex in rat cortex. European Journal of Pharmacology. 172: 239-47. PMID 2550262 DOI: 10.1016/0922-4106(89)90054-0 |
0.365 |
|
| 1989 |
Aebischer B, Frey P, Haerter H, Herrling PL, Mueller W, Olverman HJ, Watkins JC. Synthesis and NMD A Antagonistic Properties of the Enantiomers of 4‐(3‐phosphonopropyl)piperazine‐2‐carboxylic acid (CPP) and of the unsaturated analogue (E)‐4‐(3‐phosphonoprop‐2‐enyl)piperazine‐2‐carboxylic acid (CPP‐ene) Helvetica Chimica Acta. 72: 1043-1051. DOI: 10.1002/Hlca.19890720522 |
0.49 |
|
| 1989 |
Aebischer B, Frey P, Haerter HP, Herrling PL, Mueller W, Olverman HJ, Watkins JC. Synthesis and NMDA antagonistic properties of the enantiomers of 4-(3-phosphonopropyl)piperazine-2-carboxylic acid (CPP) and of the unsaturated analogue (E)-4-(3-phosphonoprop-2-enyl)piperazine-2-carboxylic acid (CPP-ene) Helvetica Chimica Acta. 72: 1043-1051. |
0.315 |
|
| 1988 |
Croucher MJ, Bradford HF, Sunter DC, Watkins JC. Inhibition of the development of electrical kindling of the prepyriform cortex by daily focal injections of excitatory amino acid antagonists. European Journal of Pharmacology. 152: 29-38. PMID 3208834 DOI: 10.1016/0014-2999(88)90832-1 |
0.368 |
|
| 1988 |
Monaghan DT, Olverman HJ, Nguyen L, Watkins JC, Cotman CW. Two classes of N-methyl-D-aspartate recognition sites: differential distribution and differential regulation by glycine. Proceedings of the National Academy of Sciences of the United States of America. 85: 9836-40. PMID 2904680 DOI: 10.1073/Pnas.85.24.9836 |
0.415 |
|
| 1988 |
Olverman HJ, Jones AW, Mewett KN, Watkins JC. Structure/activity relations of N-methyl-D-aspartate receptor ligands as studied by their inhibition of [3H]D-2-amino-5-phosphonopentanoic acid binding in rat brain membranes. Neuroscience. 26: 17-31. PMID 2901691 DOI: 10.1016/0306-4522(88)90124-8 |
0.449 |
|
| 1988 |
Olverman HJ, Jones AW, Watkins JC. [3H]D-2-amino-5-phosphonopentanoate as a ligand for N-methyl-D-aspartate receptors in the mammalian central nervous system. Neuroscience. 26: 1-15. PMID 2901689 DOI: 10.1016/0306-4522(88)90123-6 |
0.452 |
|
| 1988 |
Bridges RJ, Kadri MM, Monaghan DT, Nunn PB, Watkins JC, Cotman CW. Inhibition of [3H]alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid binding by the excitotoxin beta-N-oxalyl-L-alpha,beta-diaminopropionic acid. European Journal of Pharmacology. 145: 357-9. PMID 2895006 DOI: 10.1016/0014-2999(88)90442-6 |
0.367 |
|
| 1988 |
Childs AM, Evans RH, Watkins JC. The pharmacological selectivity of three NMDA antagonists. European Journal of Pharmacology. 145: 81-6. PMID 2894999 DOI: 10.1016/0014-2999(88)90352-4 |
0.482 |
|
| 1987 |
Turski L, Meldrum BS, Turski WA, Watkins JC. Evidence that antagonism at non-NMDA receptors results in anticonvulsant action. European Journal of Pharmacology. 136: 69-73. PMID 3036544 DOI: 10.1016/0014-2999(87)90780-1 |
0.428 |
|
| 1987 |
Honoré T, Drejer J, Nielsen M, Watkins JC, Olverman HJ. Molecular target size of NMDA antagonist binding sites. European Journal of Pharmacology. 136: 137-8. PMID 3036542 DOI: 10.1016/0014-2999(87)90793-X |
0.326 |
|
| 1987 |
Turski L, Klockgether T, Sontag KH, Herrling PL, Watkins JC. Muscle relaxant and anticonvulsant activity of 3-((+/-)-2-carboxypiperazin-4-yl)-propyl-1-phosphonic acid, a novel N-methyl-D-aspartate antagonist, in rodents. Neuroscience Letters. 73: 143-8. PMID 3029636 DOI: 10.1016/0304-3940(87)90008-5 |
0.433 |
|
| 1987 |
Watkins JC, Olverman HJ. Agonists and antagonists for excitatory amino acid receptors Trends in Neurosciences. 10: 265-272. DOI: 10.1016/0166-2236(87)90171-8 |
0.391 |
|
| 1986 |
Olverman HJ, Monaghan DT, Cotman CW, Watkins JC. [3H]CPP, a new competitive ligand for NMDA receptors. European Journal of Pharmacology. 131: 161-2. PMID 3028828 DOI: 10.1016/0014-2999(86)90533-9 |
0.398 |
|
| 1986 |
Ganong AH, Jones AW, Watkins JC, Cotman CW. Parallel antagonism of synaptic transmission and kainate/quisqualate responses in the hippocampus by piperazine-2,3-dicarboxylic acid analogs. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 6: 930-7. PMID 3009733 |
0.377 |
|
| 1986 |
Harris EW, Ganong AH, Monaghan DT, Watkins JC, Cotman CW. Action of 3-((+/-)-2-carboxypiperazin-4-yl)-propyl-1-phosphonic acid (CPP): a new and highly potent antagonist of N-methyl-D-aspartate receptors in the hippocampus. Brain Research. 382: 174-7. PMID 2876750 DOI: 10.1016/0006-8993(86)90128-9 |
0.534 |
|
| 1986 |
Davies J, Evans RH, Herrling PL, Jones AW, Olverman HJ, Pook P, Watkins JC. CPP, a new potent and selective NMDA antagonist. Depression of central neuron responses, affinity for [3H]D-AP5 binding sites on brain membranes and anticonvulsant activity. Brain Research. 382: 169-73. PMID 2876749 DOI: 10.1016/0006-8993(86)90127-7 |
0.5 |
|
| 1986 |
Ganong A, Jones A, Watkins J, Cotman C. Parallel antagonism of synaptic transmission and kainate/quisqualate responses in the hippocampus by piperazine-2,3-dicarboxylic acid analogs The Journal of Neuroscience. 6: 930-937. DOI: 10.1523/Jneurosci.06-04-00930.1986 |
0.477 |
|
| 1985 |
Chapman AG, Hart GP, Meldrum BS, Turski L, Watkins JC. Anticonvulsant activity of two novel piperazine derivatives with potent kainate antagonist activity. Neuroscience Letters. 55: 325-30. PMID 3892372 DOI: 10.1016/0304-3940(85)90456-2 |
0.473 |
|
| 1985 |
Davies J, Francis AA, Oakes DJ, Sheardown MJ, Watkins JC. Selective potentiating effect of beta-p-chlorophenylglutamate on responses induced by certain sulphur-containing excitatory amino acids and quisqualate. Neuropharmacology. 24: 177-80. PMID 3887200 DOI: 10.1016/0028-3908(85)90178-9 |
0.467 |
|
| 1985 |
Davies J, Watkins JC. Depressant actions of gamma-D-glutamylaminomethyl sulfonate (GAMS) on amino acid-induced and synaptic excitation in the cat spinal cord. Brain Research. 327: 113-20. PMID 3838689 DOI: 10.1016/0006-8993(85)91505-7 |
0.397 |
|
| 1985 |
Turski L, Meldrum BS, Jones AW, Watkins JC. Anticonvulsant action of stereoisomers of gamma-glutamylaminomethylsulphonic acid in mice. European Journal of Pharmacology. 111: 279-83. PMID 2990954 DOI: 10.1016/0014-2999(85)90769-1 |
0.484 |
|
| 1984 |
Jones AW, Smith DA, Watkins JC. Structure-activity relations of dipeptide antagonists of excitatory amino acids. Neuroscience. 13: 573-81. PMID 6392929 DOI: 10.1016/0306-4522(84)90250-1 |
0.435 |
|
| 1984 |
Monaghan DT, Yao D, Olverman HJ, Watkins JC, Cotman CW. Autoradiography of D-2-[3H]amino-5-phosphonopentanoate binding sites in rat brain. Neuroscience Letters. 52: 253-8. PMID 6151632 DOI: 10.1016/0304-3940(84)90170-8 |
0.398 |
|
| 1984 |
Jones AW, Croucher MJ, Meldrum BS, Watkins JC. Suppression of audiogenic seizures in DBA/2 mice by two new dipeptide NMDA receptor antagonists. Neuroscience Letters. 45: 157-61. PMID 6145126 DOI: 10.1016/0304-3940(84)90092-2 |
0.425 |
|
| 1984 |
Olverman HJ, Jones AW, Watkins JC. L-glutamate has higher affinity than other amino acids for [3H]-D-AP5 binding sites in rat brain membranes. Nature. 307: 460-2. PMID 6141527 DOI: 10.1038/307460A0 |
0.529 |
|
| 1984 |
Davies J, Jones AW, Sheardown MJ, Smith DA, Watkins JC. Phosphono dipeptides and piperazine derivatives as antagonists of amino acid-induced and synaptic excitation in mammalian and amphibian spinal cord. Neuroscience Letters. 52: 79-84. PMID 6098881 DOI: 10.1016/0304-3940(84)90354-9 |
0.513 |
|
| 1983 |
Davies J, Watkins JC. Role of excitatory amino acid receptors in mono- and polysynaptic excitation in the cat spinal cord. Experimental Brain Research. 49: 280-90. PMID 6131834 DOI: 10.1007/BF00238587 |
0.469 |
|
| 1982 |
Evans RH, Francis AA, Jones AW, Smith DA, Watkins JC. The effects of a series of omega-phosphonic alpha-carboxylic amino acids on electrically evoked and excitant amino acid-induced responses in isolated spinal cord preparations. British Journal of Pharmacology. 75: 65-75. PMID 7042024 DOI: 10.1111/J.1476-5381.1982.Tb08758.X |
0.493 |
|
| 1982 |
Davies J, Evans RH, Francis AA, Jones AW, Smith DA, Watkins JC. Conformational aspects of the actions of some piperidine dicarboxylic acids at excitatory amino acid receptors in the mammalian and amphibian spinal cord. Neurochemical Research. 7: 1119-33. PMID 6294543 DOI: 10.1007/Bf00964890 |
0.527 |
|
| 1982 |
Davies J, Watkins JC. Actions of D and L forms of 2-amino-5-phosphonovalerate and 2-amino-4-phosphonobutyrate in the cat spinal cord. Brain Research. 235: 378-86. PMID 6145492 DOI: 10.1016/0006-8993(82)91017-4 |
0.394 |
|
| 1982 |
Davies J, Evans RH, Jones AW, Smith DA, Watkins JC. Differential activation and blockade of excitatory amino acid receptors in the mammalian and amphibian central nervous systems. Comparative Biochemistry and Physiology. C: Comparative Pharmacology. 72: 211-24. PMID 6128141 DOI: 10.1016/0306-4492(82)90086-7 |
0.565 |
|
| 1982 |
Davies J, Watkins JC. Selective excitatory amino acid antagonist action of γ-D-glutamyl-aminomethyl-sulphonate (GAMS) on cat spinal neurones Journal of Physiology. 108P-109P. |
0.334 |
|
| 1981 |
Davies J, Watkins JC. Pharmacology of glutamate and aspartate antagonists on cat spinal neurones. Advances in Biochemical Psychopharmacology. 27: 275-84. PMID 7446276 |
0.333 |
|
| 1981 |
Davies J, Evans RH, Francis AA, Jones AW, Watkins JC. Antagonism of excitatory amino acid-induced and synaptic excitation of spinal neurones by cis-2,3-piperidine dicarboxylate. Journal of Neurochemistry. 36: 1305-7. PMID 7009789 DOI: 10.1111/J.1471-4159.1981.Tb01736.X |
0.503 |
|
| 1981 |
Davies J, Watkins JC. Differentiation of kainate and quisqualate receptors in the cat spinal cord by selective antagonism with gamma-D(and L)-glutamylglycine. Brain Research. 206: 172-7. PMID 6258721 DOI: 10.1016/0006-8993(81)90111-6 |
0.434 |
|
| 1981 |
Watkins JC, Evans RH. Excitatory amino acid transmitters. Annual Review of Pharmacology and Toxicology. 21: 165-204. PMID 6112965 DOI: 10.1146/Annurev.Pa.21.040181.001121 |
0.381 |
|
| 1981 |
Davies J, Francis AA, Jones AW, Watkins JC. 2-Amino-5-phosphonovalerate (2APV), a potent and selective antagonist of amino acid-induced and synaptic excitation. Neuroscience Letters. 21: 77-81. PMID 6111052 DOI: 10.1016/0304-3940(81)90061-6 |
0.529 |
|
| 1981 |
Watkins JC, Davies J, Evans RH, Francis AA, Jones AW. Pharmacology of receptors for excitatory amino acids. Advances in Biochemical Psychopharmacology. 27: 263-73. PMID 6108694 |
0.368 |
|
| 1981 |
Evans RH, Smith DAS, Watkins JC. Differential role of excitant amino acid receptors in spinal transmission Journal of Physiology. 55P. |
0.347 |
|
| 1981 |
Evans RH, Jones AW, Watkins JC. Depressant action of the L-glutamate analogue (+)2-amino-4-phosphonobutyrate British Journal of Pharmacology. 74: 907P. |
0.318 |
|
| 1980 |
Francis AA, Jones AW, Watkins JC. Dipeptide antagonists of amino acid-induced and synaptic excitation in the frog spinal cord. Journal of Neurochemistry. 35: 1458-60. PMID 6969293 |
0.383 |
|
| 1980 |
Ault B, Evans RH, Francis AA, Oakes DJ, Watkins JC. Selective depression of excitatory amino acid induced depolarizations by magnesium ions in isolated spinal cord preparations. The Journal of Physiology. 307: 413-28. PMID 6259339 |
0.33 |
|
| 1980 |
Watkins JC. NMDA receptors. New light on amino acid-mediated synaptic excitation Trends in Neurosciences. 3: 61-64. DOI: 10.1016/S0166-2236(80)80153-6 |
0.365 |
|
| 1980 |
Davies J, Francis AA, Jones AW, Watkins JC. Dipeptide antagonists of amino acid-induced and synaptic excitation in the vertebrate central nervous system Journal of Physiology. 21p-22p. |
0.307 |
|
| 1980 |
Davies J, Francis AA, Jones AW, Watkins JC. 2-Amino-5-phosphonovalerate (2APV), a highly potent and specific antagonist at spinal NMDA receptors British Journal of Pharmacology. 70: 52p-53p. |
0.416 |
|
| 1979 |
Davies J, Watkins JC. Selective antagonism of amino acid-induced and synaptic excitation in the cat spinal cord. The Journal of Physiology. 297: 621-35. PMID 536925 |
0.478 |
|
| 1979 |
Evans RH, Francis AA, Hunt K, Oakes DJ, Watkins JC. Antagonism of excitatory amino acid-induced responses and of synaptic excitation in the isolated spinal cord of the frog. British Journal of Pharmacology. 67: 591-603. PMID 316343 DOI: 10.1111/J.1476-5381.1979.Tb08706.X |
0.572 |
|
| 1979 |
Davies J, Evans RH, Francis AA, Watkins JC. Excitatory amino acid receptors and synaptic excitation in the mammalian central nervous system. Journal De Physiologie. 75: 641-54. PMID 232719 |
0.471 |
|
| 1978 |
Evans RH, Watkins JC. Specific antagonism of excitant amino acids in the isolated spinal cord of the neonatal rat. European Journal of Pharmacology. 50: 123-9. PMID 210025 DOI: 10.1016/0014-2999(78)90007-9 |
0.47 |
|
| 1978 |
Biscoe TJ, Davies J, Dray A, Evans RH, Martin MR, Watkins JC. D-alpha-aminoadipate, alpha, epsilon-diominopimelic acid and HA-966 as antagonists of amino acid-induced and synpatic excitation of mammalian spinal neurones in vivo. Brain Research. 148: 543-8. PMID 207393 DOI: 10.1016/0006-8993(78)90745-X |
0.415 |
|
| 1978 |
Evans RH, Francis AA, Watkins JC. Mg2+-like selective antagonism of excitatory amino acid-induced responses by alpha, epsilon-diaminopimelic acid, D-alpha-aminoadipate and HA-966 in isolated spinal cord of frog and immature rat. Brain Research. 148: 536-42. PMID 207392 DOI: 10.1016/0006-8993(78)90744-8 |
0.422 |
|
| 1978 |
Evans RH, Francis AA, Hunt K, Martin MR, Watkins JC. Quisqualamine, a novel gamma-aminobutyric acid (GABA) related depressant amino acid. The Journal of Pharmacy and Pharmacology. 30: 364-7. PMID 26767 DOI: 10.1111/J.2042-7158.1978.Tb13257.X |
0.416 |
|
| 1977 |
Biscoe TJ, Davies J, Dray A, Evans RH, Francis AA, Martin MR, Watkins JC. Depression of synaptic excitation and of amino acid induced excitatory responses of spinal neurones by D-alpha-aminoadipate, alpha,epsilon-diaminopimelic acid and HA-966. European Journal of Pharmacology. 45: 315-6. PMID 923641 DOI: 10.1016/0014-2999(77)90017-6 |
0.435 |
|
| 1977 |
Taberner PV, Pearce MJ, Watkins JC. The inhibition of mouse brain glutamate decarboxylase by some structural analogues of L-glutamic acid. Biochemical Pharmacology. 26: 345-9. PMID 849326 DOI: 10.1016/0006-2952(77)90188-5 |
0.412 |
|
| 1977 |
Evans RH, Francis AA, Watkins JC. Effects of monovalent cations on the responses of motoneurones to different groups to amino acid excitants in frog and rat spinal cord. Experientia. 33: 246-8. PMID 844576 DOI: 10.1007/Bf02124092 |
0.387 |
|
| 1977 |
Evans RH, Francis AA, Watkins JC. Differential antagonism by chlorpromazine and diazepam of frog motoneurone depolarization induced by glutamate-related amino acids. European Journal of Pharmacology. 44: 325-30. PMID 302213 DOI: 10.1016/0014-2999(77)90306-5 |
0.467 |
|
| 1977 |
Evans RH, Francis AA, Watkins JC. Selective antagonism by Mg2+ of amino acid-induced depolarization of spinal neurones. Experientia. 33: 489-91. PMID 301099 DOI: 10.1007/Bf01922227 |
0.481 |
|
| 1977 |
Biscoe TJ, Evans RH, Francis AA, Martin MR, Watkins JC, Davies J, Dray A. D-alpha-Aminoadipate as a selective antagonist of amino acid-induced and synaptic excitation of mammalian spinal neurones. Nature. 270: 743-5. PMID 22820 DOI: 10.1038/270743A0 |
0.449 |
|
| 1977 |
Watkins JC, Curtis DR, Brand SS. Phosphonic analogues as antagonists of amino acid excitants. The Journal of Pharmacy and Pharmacology. 29: 324. PMID 17707 |
0.482 |
|
| 1976 |
Evans RH, Francis AA, Watkins JC. Bimodal action of glycine on frog spinal motoneurones. Brain Research. 118: 395-401. PMID 1087578 DOI: 10.1016/0006-8993(76)90307-3 |
0.472 |
|
| 1976 |
Biscoe TJ, Headley PM, Lodge D, Martin MR, Watkins JC. The sensitivity of rat spinal interneurones and renshaw cells to L-glutamate and L-aspartate. Experimental Brain Research. 26: 547-51. PMID 1010006 DOI: 10.1007/BF00238827 |
0.334 |
|
| 1976 |
Biscoe TJ, Evans RH, Headley PM, Martin MR, Watkins JC. Structure-activity relations of excitatory amino acids on frog and rat spinal neurones. British Journal of Pharmacology. 58: 373-82. PMID 990592 DOI: 10.1111/J.1476-5381.1976.Tb07714.X |
0.507 |
|
| 1975 |
Biscoe TJ, Evans RH, Headley PM, Martin M, Watkins JC. Domoic and quisqualic acids as potent amino acid excitants of frog and rat spinal neurones Nature. 255: 166-167. PMID 1128682 DOI: 10.1038/255166A0 |
0.46 |
|
| 1975 |
Evans RH, Watkins JC. Ventral root responses of the hemisected amphibian spinal cord to perfused amino acids in the presence of procaine. British Journal of Pharmacology. 55: 519-26. PMID 813800 |
0.32 |
|
| 1972 |
Curtis DR, Duggan AW, Felix D, Johnston GA, Teb ecis AK, Watkins JC. Excitation of mammalian central neurones by acidic amino acids. Brain Research. 41: 283-301. PMID 4402606 DOI: 10.1016/0006-8993(72)90503-3 |
0.561 |
|
| 1972 |
DAVIES J, WATKINS JC. Is 1-Hydroxy-3-aminopyrrolidone-2 (HA-966) a Selective Excitatory Amino-acid Antagonist? Nature New Biology. 238: 61-63. DOI: 10.1038/NEWBIO238061A0 |
0.303 |
|
| 1971 |
Watkins JC, Curtis DR, Felix D. Effect of intracellular injection of pyridine nucleotides on electrical responses of cat spinal motoneurones. Brain Research. 35: 570-2. PMID 4332606 |
0.411 |
|
| 1966 |
Watkins JC, Curtis DR, Biscoe TJ. Central effects of beta-N-oxalyl-alpha,beta-diaminopropionic acid and other lathyrus factors. Nature. 211: 637. PMID 5968735 |
0.374 |
|
| 1966 |
Curtis DR, Ryall RW, Watkins JC. The action of cholinomimetics on spinal interneurones. Experimental Brain Research. 2: 97-106. PMID 5921136 |
0.405 |
|
| 1965 |
Curtis DR, Watkins JC. The pharmacology of amino acids related to gamma-aminobutyric acid. Pharmacological Reviews. 17: 347-91. PMID 5321711 |
0.434 |
|
| 1964 |
RYALL RW, STONE NE, CURTIS DR, WATKINS JC. ACTION OF ACETYLCHOLINE EXTRACTED FROM BRAIN ON SPINAL RENSHAW CELLS. Nature. 201: 1034-5. PMID 14191577 |
0.37 |
|
| 1963 |
CURTIS DR, WATKINS JC. Acidic amino acids with strong excitatory actions on mammalian neurones. The Journal of Physiology. 166: 1-14. PMID 14024354 |
0.463 |
|
| 1961 |
CURTIS DR, PHILLIS JW, WATKINS JC. Cholinergic and non-cholinergic transmission in the mammalian spinal cord. The Journal of Physiology. 158: 296-323. PMID 13882769 |
0.551 |
|
| 1961 |
CURTIS DR, WATKINS JC. Analogues of glutamic and gamma-amino-n-butyric acids having potent actions on mammalian neurones. Nature. 191: 1010-1. PMID 13718947 |
0.501 |
|
| 1961 |
CURTIS DR, PHILLIS JW, WATKINS JC. Actions of aminoacids on the isolated hemisected spinal cord of the toad. British Journal of Pharmacology and Chemotherapy. 16: 262-83. PMID 13718946 |
0.636 |
|
| 1960 |
CURTIS DR, PHILLIS JW, WATKINS JC. The chemical excitation of spinal neurones by certain acidic amino acids. The Journal of Physiology. 150: 656-82. PMID 13813400 |
0.597 |
|
| 1960 |
CURTIS DR, WATKINS JC. The excitation and depression of spinal neurones by structurally related amino acids. Journal of Neurochemistry. 6: 117-41. PMID 13718948 |
0.475 |
|
| 1960 |
CURTIS DR, PERRIN DD, WATKINS JC. The excitation of spinal neurones by the ionophoretic application of agents which chelate calcium. Journal of Neurochemistry. 6: 1-20. PMID 13718945 |
0.387 |
|
| 1959 |
CURTIS DR, PHILLIS JW, WATKINS JC. The depression of spinal neurones by gamma-amino-n-butyric acid and beta-alanine. The Journal of Physiology. 146: 185-203. PMID 13655226 DOI: 10.1113/jphysiol.1959.sp006188 |
0.595 |
|
| 1959 |
CURTIS DR, PHILLIS JW, WATKINS JC. Chemical excitation of spinal neurones. Nature. 183: 611-2. PMID 13632811 |
0.548 |
|
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