| Year |
Citation |
Score |
| 1991 |
Miller JA, Surh YJ, Liem A, Miller EC. Electrophilic sulfuric acid ester metabolites of hydroxy-methyl aromatic hydrocarbons as precursors of hepatic benzylic DNA adducts in vivo. Advances in Experimental Medicine and Biology. 283: 555-67. PMID 1906227 DOI: 10.1007/978-1-4684-5877-0_71 |
0.461 |
|
| 1991 |
Surh YJ, Liem A, Miller EC, Miller JA. 7-Sulfooxymethyl-12-methylbenz[a]anthracene is an electrophilic mutagen, but does not appear to play a role in carcinogenesis by 7,12-dimethylbenz[a]anthracene or 7-hydroxymethyl-12-methylbenz[a]anthracene. Carcinogenesis. 12: 339-47. PMID 1899811 DOI: 10.1093/Carcin/12.2.339 |
0.533 |
|
| 1991 |
Surh YJ, Liem A, Miller EC, Miller JA. Age- and sex-related differences in activation of the carcinogen 7-hydroxymethyl-12-methylbenz[a]anthracene to an electrophilic sulfuric acid ester metabolite in rats. Possible involvement of hydroxysteroid sulfotransferase activity. Biochemical Pharmacology. 41: 213-21. PMID 1824923 DOI: 10.1016/0006-2952(91)90479-O |
0.555 |
|
| 1990 |
Surh YJ, Liem A, Miller EC, Miller JA. The strong hepatocarcinogenicity of the electrophilic and mutagenic metabolite 6-sulfooxymethylbenzo[a]pyrene and its formation of benzylic DNA adducts in the livers of infant male B6C3F1 mice. Biochemical and Biophysical Research Communications. 172: 85-91. PMID 2222484 DOI: 10.1016/S0006-291X(05)80176-7 |
0.559 |
|
| 1990 |
Leithauser MT, Liem A, Stewart BC, Miller EC, Miller JA. 1,N6-ethenoadenosine formation, mutagenicity and murine tumor induction as indicators of the generation of an electrophilic epoxide metabolite of the closely related carcinogens ethyl carbamate (urethane) and vinyl carbamate. Carcinogenesis. 11: 463-73. PMID 1690091 DOI: 10.1093/Carcin/11.3.463 |
0.51 |
|
| 1990 |
Leithauser MT, Liem A, Stewart BC, Miller EC, Miller JA. 1,n ethenoadenosine formation, mutagenicity and murine tumor induction as indicators of the generation of an electro philic epoxide metabolite of the closely related carcinogens ethyl carbamate (urethane) and vinyl carbamate Carcinogenesis. 11: 1250. DOI: 10.1093/carcin/11.7.1250 |
0.451 |
|
| 1989 |
Surh YJ, Liem A, Miller EC, Miller JA. Metabolic activation of the carcinogen 6-hydroxymethylbenzo[a]pyrene: formation of an electrophilic sulfuric acid ester and benzylic DNA adducts in rat liver in vivo and in reactions in vitro. Carcinogenesis. 10: 1519-28. PMID 2752526 DOI: 10.1093/Carcin/10.8.1519 |
0.51 |
|
| 1988 |
Lai CC, Miller EC, Miller JA, Liem A. The essential role of microsomal deacetylase activity in the metabolic activation, DNA-(deoxyguanosin-8-yl)-2-aminofluorene adduct formation and initiation of liver tumors by N-hydroxy-2-acetylaminofluorene in the livers of infant male B6C3F1 mice. Carcinogenesis. 9: 1295-302. PMID 3383346 DOI: 10.1093/Carcin/9.7.1295 |
0.527 |
|
| 1988 |
Stowers SJ, Wiseman RW, Ward JM, Miller EC, Miller JA, Anderson MW, Eva A. Detection of activated proto-oncogenes in N-nitrosodiethylamine-induced liver tumors: a comparison between B6C3F1 mice and Fischer 344 rats. Carcinogenesis. 9: 271-6. PMID 2827904 DOI: 10.1093/carcin/9.2.271 |
0.461 |
|
| 1987 |
Lai CC, Miller EC, Miller JA, Liem A. Initiation of hepatocarcinogenesis in infant male B6C3F1 mice by N-hydroxy-2-aminofluorene or N-hydroxy-2-acetylaminofluorene depends primarily on metabolism to N-sulfooxy-2-aminofluorene and formation of DNA-(deoxyguanosin-8-yl)-2-aminofluorene adducts. Carcinogenesis. 8: 471-8. PMID 3815742 DOI: 10.1093/Carcin/8.3.471 |
0.562 |
|
| 1987 |
Wiseman RW, Miller EC, Miller JA, Liem A. Structure-activity studies of the hepatocarcinogenicities of alkenylbenzene derivatives related to estragole and safrole on administration to preweanling male C57BL/6J x C3H/HeJ F1 mice. Cancer Research. 47: 2275-83. PMID 3567921 DOI: 10.1016/0378-8741(88)90255-3 |
0.446 |
|
| 1987 |
Boberg EW, Liem A, Miller EC, Miller JA. Inhibition by pentachlorophenol of the initiating and promoting activities of 1'-hydroxysafrole for the formation of enzyme-altered foci and tumors in rat liver. Carcinogenesis. 8: 531-9. PMID 2881629 DOI: 10.1093/Carcin/8.4.531 |
0.55 |
|
| 1987 |
Surh YJ, Lai CC, Miller JA, Miller EC. Hepatic DNA and RNA adduct formation from the carcinogen 7-hydroxymethyl-12-methylbenz[a]anthracene and its electrophilic sulfuric acid ester metabolite in preweanling rats and mice. Biochemical and Biophysical Research Communications. 144: 576-82. PMID 2437917 DOI: 10.1016/S0006-291X(87)80005-0 |
0.577 |
|
| 1986 |
Fennell TR, Juhl U, Miller EC, Miller JA. Identification and quantitation of hepatic DNA adducts formed in B6C3F1 mice from 1'-hydroxy-2',3'-dehydroestragole: comparison of the adducts detected with the 1'-3H-labelled carcinogen and by 32P-postlabelling. Carcinogenesis. 7: 1881-7. PMID 3769137 DOI: 10.1093/Carcin/7.11.1881 |
0.484 |
|
| 1986 |
Miller JA, Miller EC. Electrophilic sulfuric acid ester metabolites as ultimate carcinogens. Advances in Experimental Medicine and Biology. 197: 583-95. PMID 3766283 DOI: 10.1007/978-1-4684-5134-4_55 |
0.447 |
|
| 1986 |
Boberg EW, Miller EC, Miller JA. The metabolic sulfonation and side-chain oxidation of 3'-hydroxyisosafrole in the mouse and its inactivity as a hepatocarcinogen relative to 1'-hydroxysafrole. Chemico-Biological Interactions. 59: 73-97. PMID 3757147 DOI: 10.1016/S0009-2797(86)80056-4 |
0.53 |
|
| 1986 |
Miller EC, Miller JA. Carcinogens and mutagens that may occur in foods. Cancer. 58: 1795-803. PMID 3756803 DOI: 10.1002/1097-0142(19861015)58:8+<1795::Aid-Cncr2820581403>3.0.Co;2-H |
0.429 |
|
| 1986 |
Wiseman RW, Drinkwater NR, Miller JA, Miller EC, Blomquist JC. Apurinic/apyrimidinic site induction in supercoiled DNA and mutagenesis in Salmonella typhimurium TA100 by 1'-acetoxysafrole and related electrophilic alkenylbenzene derivatives. Carcinogenesis. 7: 2089-93. PMID 3536144 DOI: 10.1093/Carcin/7.12.2089 |
0.436 |
|
| 1986 |
Wiseman RW, Stowers SJ, Miller EC, Anderson MW, Miller JA. Activating mutations of the c-Ha-ras protooncogene in chemically induced hepatomas of the male B6C3 F1 mouse. Proceedings of the National Academy of Sciences of the United States of America. 83: 5825-9. PMID 3016723 DOI: 10.1073/Pnas.83.16.5825 |
0.402 |
|
| 1986 |
Delclos KB, Miller EC, Miller JA, Liem A. Sulfuric acid esters as major ultimate electrophilic and hepatocarcinogenic metabolites of 4-aminoazobenzene and its N-methyl derivatives in infant male C57BL/6J x C3H/HeJ F1 (B6C3F1) mice. Carcinogenesis. 7: 277-87. PMID 2419005 |
0.492 |
|
| 1985 |
Wiseman RW, Fennell TR, Miller JA, Miller EC. Further characterization of the DNA adducts formed by electrophilic esters of the hepatocarcinogens 1'-hydroxysafrole and 1'-hydroxyestragole in vitro and in mouse liver in vivo, including new adducts at C-8 and N-7 of guanine residues. Cancer Research. 45: 3096-105. PMID 4005847 |
0.459 |
|
| 1985 |
Miller EC, Miller JA, Boberg EW, Delclos KB, Lai CC, Fennell TR, Wiseman RW, Liem A. Sulfuric acid esters as ultimate electrophilic and carcinogenic metabolites of some alkenylbenzenes and aromatic amines in mouse liver. Carcinogenesis; a Comprehensive Survey. 10: 93-107. PMID 3904999 |
0.459 |
|
| 1985 |
Fennell TR, Wiseman RW, Miller JA, Miller EC. Major role of hepatic sulfotransferase activity in the metabolic activation, DNA adduct formation, and carcinogenicity of 1'-hydroxy-2',3'-dehydroestragole in infant male C57BL/6J x C3H/HeJ F1 mice. Cancer Research. 45: 5310-20. PMID 3863702 |
0.508 |
|
| 1985 |
Lai CC, Miller JA, Miller EC, Liem A. N-sulfoöxy-2-aminofluorene is the major ultimate electrophilic and carcinogenic metabolite of N-hydroxy-2-acetylaminofluorene in the livers of infant male C57BL/6J x C3H/HeJ F1 (B6C3F1) mice. Carcinogenesis. 6: 1037-45. PMID 3860305 DOI: 10.1093/Carcin/6.7.1037 |
0.576 |
|
| 1985 |
Preston BD, Miller EC, Miller JA. The activities of 2,2',5,5'-tetrachlorobiphenyl, its 3,4-oxide metabolite, and 2,2',4,4'-tetrachlorobiphenyl in tumor induction and promotion assays. Carcinogenesis. 6: 451-3. PMID 2858273 DOI: 10.1093/Carcin/6.3.451 |
0.7 |
|
| 1984 |
Fennell TR, Miller JA, Miller EC. Characterization of the biliary and urinary glutathione and N-acetylcysteine metabolites of the hepatic carcinogen 1'-hydroxysafrole and its 1'-oxo metabolite in rats and mice. Cancer Research. 44: 3231-40. PMID 6744260 |
0.535 |
|
| 1984 |
Preston BD, Miller JA, Miller EC. Reactions of 2,2',5,5'-tetrachlorobiphenyl 3,4-oxide with methionine, cysteine and glutathione in relation to the formation of methylthio-metabolites of 2,2',5,5'-tetrachlorobiphenyl in the rat and mouse. Chemico-Biological Interactions. 50: 289-312. PMID 6430573 DOI: 10.1016/0009-2797(84)90038-3 |
0.702 |
|
| 1984 |
Delclos KB, Tarpley WG, Miller EC, Miller JA. 4-aminoazobenzene and N,N-dimethyl-4-aminoazobenzene as equipotent hepatic carcinogens in male C57BL/6 X C3H/He F1 mice and characterization of N-(Deoxyguanosin-8-yl)-4-aminoazobenzene as the major persistent hepatic DNA-bound dye in these mice. Cancer Research. 44: 2540-50. PMID 6426782 |
0.519 |
|
| 1983 |
Miller EC, Swanson AB, Phillips DH, Fletcher TL, Liem A, Miller JA. Structure-activity studies of the carcinogenicities in the mouse and rat of some naturally occurring and synthetic alkenylbenzene derivatives related to safrole and estragole. Cancer Research. 43: 1124-34. PMID 6825084 |
0.454 |
|
| 1983 |
Boberg EW, Miller EC, Miller JA, Poland A, Liem A. Strong evidence from studies with brachymorphic mice and pentachlorophenol that 1'-sulfoöxysafrole is the major ultimate electrophilic and carcinogenic metabolite of 1'-hydroxysafrole in mouse liver. Cancer Research. 43: 5163-73. PMID 6577945 |
0.448 |
|
| 1983 |
Preston BD, Miller JA, Miller EC. Non-arene oxide aromatic ring hydroxylation of 2,2',5,5'-tetrachlorobiphenyl as the major metabolic pathway catalyzed by phenobarbital-induced rat liver microsomes. The Journal of Biological Chemistry. 258: 8304-11. PMID 6408087 |
0.692 |
|
| 1983 |
Miller JA, Miller EC. Some historical aspects of N-aryl carcinogens and their metabolic activation. Environmental Health Perspectives. 49: 3-12. PMID 6339227 DOI: 10.1289/Ehp.83493 |
0.437 |
|
| 1983 |
Buening MK, Levin W, Wood AW, Chang RL, Agranat I, Rabinovitz M, Buhler DR, Mah HD, Hernandez O, Simpson RB, Jerina DM, Conney AH, Miller EC, Miller JA. Fluorine substitution as a probe for the role of the 6-position of benzo[a]pyrene in carcinogenesis. Journal of the National Cancer Institute. 71: 309-15. PMID 6308321 DOI: 10.1093/Jnci/71.2.309 |
0.472 |
|
| 1983 |
Miller JA, Miller EC. The metabolic activation and nucleic acid adducts of naturally-occurring carcinogens: recent results with ethyl carbamate and the spice flavors safrole and estragole. British Journal of Cancer. 48: 1-15. PMID 6191767 |
0.493 |
|
| 1982 |
Tarpley WG, Miller JA, Miller EC. Rapid release of carcinogen-guanine adducts from DNA after reaction with N-acetoxy-2-acetylaminofluorene or N-benzoyloxy-N-methyl-4-aminoazobenzene. Carcinogenesis. 3: 81-8. PMID 7067041 DOI: 10.1093/Carcin/3.1.81 |
0.537 |
|
| 1982 |
Leopold WR, Miller JA, Miller EC. Comparison of some carcinogenic, mutagenic, and biochemical properties of S-vinylhomocysteine and ethionine. Cancer Research. 42: 4364-74. PMID 6290034 |
0.346 |
|
| 1982 |
Moore MR, Pitot HC, Miller EC, Miller JA. Cholangiocellular carcinomas induced in Syrian golden hamsters administered aflatoxin B1 in large doses. Journal of the National Cancer Institute. 68: 271-8. PMID 6278190 |
0.417 |
|
| 1982 |
Ribovich ML, Miller JA, Miller EC, Timmins LG. Labeled 1,N6-ethenoadenosine and 3,N4-ethenocytidine in hepatic RNA of mice given[ethyl-1,2(-3)H or ethyl-1(-14)C]ethyl carbamate (urethan). Carcinogenesis. 3: 539-46. PMID 6178529 DOI: 10.1093/Carcin/3.5.539 |
0.534 |
|
| 1982 |
Preston BD, Miller JA, Miller EC. Identification of cysteine and methionine adducts formed by reactions with 2,2',5,5'-tetrachlorobiphenyl-3,4-oxide (TCB-O) in vitro Proceedings of the American Association For Cancer Research. No. 238. |
0.577 |
|
| 1981 |
Miller EC, Miller JA. Reactive metabolites as key intermediates in pharmacologic and toxicologic responses: examples from chemical carcinogenesis. Advances in Experimental Medicine and Biology. 136: 1-21. PMID 7344452 DOI: 10.1007/978-1-4757-0674-1_1 |
0.461 |
|
| 1981 |
Tarpley WG, Miller JA, Miller EC. DNA adducts formed from N-benzoyloxy-N-methyl-4-aminoazobenzene in vitro and from N, N-dimethyl-4-aminoazobenzene in mouse liver. National Cancer Institute Monograph. 163-4. PMID 7341973 |
0.506 |
|
| 1981 |
Phillips DH, Hanawalt PC, Miller JA, Miller EC. The in vivo formation and repair of DNA adducts from 1'-hydroxysafrole. Journal of Supramolecular Structure and Cellular Biochemistry. 16: 83-90. PMID 7299840 DOI: 10.1002/Jsscb.1981.380160108 |
0.525 |
|
| 1981 |
Fuchs RP, Lang MC, Miller EC, Miller JA. Comparative carcinogenicities and reactivities of N-myristoyloxy-N-acetyl-2-aminofluorene and its 7-iodo derivative. Carcinogenesis. 2: 655-9. PMID 7273346 DOI: 10.1093/Carcin/2.7.655 |
0.562 |
|
| 1981 |
Miller EC, Miller JA. Searches for ultimate chemical carcinogens and their reactions with cellular macromolecules. Cancer. 47: 2327-45. PMID 7272889 DOI: 10.1002/1097-0142(19810515)47:10<2327::Aid-Cncr2820471003>3.0.Co;2-Z |
0.522 |
|
| 1981 |
Phillips DH, Miller JA, Miller EC, Adams B. N2 atom of guanine and N6 atom of adenine residues as sites for covalent binding of metabolically activated 1'-hydroxysafrole to mouse liver DNA in vivo. Cancer Research. 41: 2664-71. PMID 7248936 |
0.51 |
|
| 1981 |
Swanson AB, Miller EC, Miller JA. The side-chain epoxidation and hydroxylation of the hepatocarcinogens safrole and estragole and some related compounds by rat and mouse liver microsomes. Biochimica Et Biophysica Acta. 673: 504-16. PMID 7225430 DOI: 10.1016/0304-4165(81)90482-7 |
0.531 |
|
| 1981 |
Moore MR, Drinkwater NR, Miller EC, Miller JA, Pitot HC. Quantitative analysis of the time-dependent development of glucose-6-phosphatase-deficient foci in the livers of mice treated neonatally with diethylnitrosamine. Cancer Research. 41: 1585-93. PMID 7214332 |
0.423 |
|
| 1981 |
Leopold WR, Batzinger RP, Miller EC, Miller JA, Earhart RH. Mutagenicity, tumorigenicity, and electrophilic reactivity of the stereoisomeric platinum(II) complexes of 1,2-diaminocyclohexane. Cancer Research. 41: 4368-77. PMID 7030475 |
0.395 |
|
| 1981 |
Miller EC, Miller JA. Mechanisms of chemical carcinogenesis. Cancer. 47: 1055-64. PMID 7016297 DOI: 10.1002/1097-0142(19810301)47:5+<1055::Aid-Cncr2820471302>3.0.Co;2-3 |
0.482 |
|
| 1981 |
Phillips DH, Miller JA, Miller EC, Adams B. Structures of the DNA adducts formed in mouse liver after administration of the proximate hepatocarcinogen 1'-hydroxyestragole. Cancer Research. 41: 176-86. PMID 6969628 |
0.444 |
|
| 1980 |
Tarpley WG, Miller JA, Miller EC. Adducts from the reaction of N-benzoyloxy-N-methyl-4-aminoazobenzene with deoxyguanosine or DNA in vitro and from hepatic DNA of mice treated with N-methyl- or N,N-dimethyl-4-aminoazobenzene. Cancer Research. 40: 2493-9. PMID 7388806 |
0.498 |
|
| 1980 |
Dahl GA, Miller EC, Miller JA. Comparative carcinogenicities and mutagenicities of vinyl carbamate, ethyl carbamate, and ethyl N-hydroxycarbamate. Cancer Research. 40: 1194-203. PMID 7357549 |
0.466 |
|
| 1980 |
Scribner JD, Miller JA, Miller EC. Comparative carcinogenicities of 4-N-pyrrolidinylazobenzene, its 4'-ethyl derivative, N-methyl-5-phenylazoindoline, and N,N-dimethyl-4-aminoazobenzene in the rat. Carcinogenesis. 1: 419-21. PMID 6791849 DOI: 10.1093/Carcin/1.5.419 |
0.555 |
|
| 1980 |
Drinkwater NR, Miller EC, Miller JA. Estimation of apurinic/apyrimidinic sites and phosphotriesters in deoxyribonucleic acid treated with electrophilic carcinogens and mutagens. Biochemistry. 19: 5087-92. PMID 6779863 DOI: 10.1021/Bi00563A023 |
0.462 |
|
| 1979 |
Miller EC, Kadlubar FF, Miller JA, Pitot HC, Drinkwater NR. The N-hydroxy metabolites of N-methyl-4-aminoazobenzene and related dyes as proximate carcinogens in the rat and mouse. Cancer Research. 39: 3411-8. PMID 476670 |
0.518 |
|
| 1979 |
Leopold WR, Miller EC, Miller JA. Carcinogenicity of antitumor cis-platinum(II) coordination complexes in the mouse and rat. Cancer Research. 39: 913-8. PMID 427778 |
0.372 |
|
| 1979 |
Miller EC, Miller JA. Milestones in chemical carcinogenesis. Seminars in Oncology. 6: 445-60. PMID 394329 DOI: 10.5555/Uri:Pii:0093775479900654 |
0.372 |
|
| 1979 |
Leopold WR, Miller JA, Miller EC. S--vinyl homocysteine, an analog of ethionine that is highly mutagenic for S. typhimurium TA100. Biochemical and Biophysical Research Communications. 88: 395-401. PMID 380563 DOI: 10.1016/0006-291X(79)92061-8 |
0.508 |
|
| 1979 |
Swanson AB, Chambliss DD, Blomquist JC, Miller EC, Miller JA. The mutagenicities of safrole, estragole, eugenol, trans-anethole, and some of their known or possible metabolites for Salmonella typhimurium mutants. Mutation Research. 60: 143-53. PMID 379623 DOI: 10.1016/0027-5107(79)90178-7 |
0.529 |
|
| 1979 |
Kitagawa T, Pitot HC, Miller EC, Miller JA. Promotion by dietary phenobarbital of hepatocarcinogenesis by 2-methyl-N,N-dimethyl-4-aminoazobenzene in the rat. Cancer Research. 39: 112-5. PMID 104788 |
0.497 |
|
| 1978 |
Dahl GA, Miller JA, Miller EC. Vinyl carbamate as a promutagen and a more carcinogenic analog of ethyl carbamate. Cancer Research. 38: 3793-804. PMID 359128 |
0.513 |
|
| 1978 |
Drinkwater NR, Miller JA, Miller EC, Yang NC. Covalent intercalative binding to DNA in relation to the mutagenicity of hydrocarbon epoxides and N-acetoxy-2-acetylaminofluorene. Cancer Research. 38: 3247-55. PMID 356963 |
0.421 |
|
| 1978 |
Kadlubar FF, Miller JA, Miller EC. Guanyl O6-arylamination and O6-arylation of DNA by the carcinogen N-hydroxy-1-naphthylamine. Cancer Research. 38: 3628-38. PMID 29702 |
0.463 |
|
| 1978 |
Lin JK, Kennan KA, Miller EC, Miller JA. Reduced nicotinamide adenine dinucleotide phosphate-dependent formation of 2,3-dihydro-2,3-dihydroxyaflatoxin B1 from aflatoxin B1 by hepatic microsomes. Cancer Research. 38: 2424-8. PMID 27299 |
0.472 |
|
| 1977 |
Lin JK, Miller JA, Miller EC. 2,3-Dihydro-2-(guan-7-yl)-3-hydroxy-aflatoxin B1, a major acid hydrolysis product of aflatoxin B1-DNA or -ribosomal RNA adducts formed in hepatic microsome-mediated reactions and in rat liver in vivo. Cancer Research. 37: 4430-8. PMID 922734 |
0.474 |
|
| 1977 |
Bartsch H, Malaveille C, Stich HF, Miller EC, Miller JA. Comparative electrophilicity, mutagenicity, DNA repair induction activity, and carcinogenicity of some N- and O-acyl derivatives of N-hydroxy-2-aminoflourene. Cancer Research. 37: 1461-7. PMID 322856 |
0.483 |
|
| 1977 |
Wislocki PG, Miller EC, Miller JA, McCoy EC, Rosenkranz HS. Carcinogenic and mutagenic activities of safrole, 1'-hydroxysafrole, and some known or possible metabolites. Cancer Research. 37: 1883-91. PMID 192464 |
0.414 |
|
| 1977 |
Swenson DH, Lin JK, Miller EC, Miller JA. Aflatoxin B1-2,3-oxide as a probable intermediate in the covalent binding of aflatoxins B1 and B2 to rat liver DNA and ribosomal RNA in vivo. Cancer Research. 37: 172-81. PMID 187331 |
0.448 |
|
| 1977 |
Kadlubar FF, Miller JA, Miller EC. Hepatic microsomal N-glucuronidation and nucleic acid binding of N-hydroxy arylamines in relation to urinary bladder carcinogenesis. Cancer Research. 37: 805-14. PMID 13929 |
0.476 |
|
| 1976 |
Kadlubar FF, Miller JA, Miller EC. Hepatic metabolism of N-hydroxy-N-methyl-4-aminoazobenzene and other N-hydroxy arylamines to reactive sulfuric acid esters. Cancer Research. 36: 2350-9. PMID 819129 |
0.504 |
|
| 1976 |
Kadlubar FF, Miller JA, Miller EC. Microsomal N-oxidation of the hepatocarcinogen N-methyl-4-aminoazobenzene and the reactivity of N-hydroxy-N-methyl-4-aminoazobenzene. Cancer Research. 36: 1196-1206. PMID 814998 |
0.486 |
|
| 1976 |
Miller EC, Miller JA. Hepatocarcinogenesis by chemicals. Progress in Liver Diseases. 5: 699-711. PMID 775563 |
0.343 |
|
| 1976 |
Miller JA, Miller EC. Carcinogens occurring naturally in foods. Federation Proceedings. 35: 1316-21. PMID 770205 |
0.398 |
|
| 1976 |
Drinkwater NR, Miller EC, Miller JA, Pitot HC. Hepatocarcinogenicity of estragole (1-allyl-4-methoxybenzene) and 1'-hydroxyestragole in the mouse and mutagenicity of 1'-acetoxyestragole in bacteria. Journal of the National Cancer Institute. 57: 1323-31. PMID 187802 DOI: 10.1093/Jnci/57.6.1323 |
0.417 |
|
| 1976 |
Wislocki PG, Borchert P, Miller JA, Miller EC. The metabolic activation of the carcinogen 1'-hydroxysafrole in vivo and in vitro and the electrophilic reactivities of possible ultimate carcinogens. Cancer Research. 36: 1686-95. PMID 5188 |
0.49 |
|
| 1975 |
Miller JA, Miller EC. Metabolic activation and reactivity of chemical carcinogens. Mutation Research. 33: 25-6. PMID 1202335 DOI: 10.1016/0027-5107(75)90039-1 |
0.468 |
|
| 1975 |
Wislocki PG, Miller JA, Miller EC. The carcinogenic and electrophilic activities of N-benzoyloxy derivatives of N-methyl-4-aminoazobenzene and related dyes. Cancer Research. 35: 880-5. PMID 1116146 |
0.481 |
|
| 1975 |
Lin JK, Miller JA, Miller EC. Structures of hepatic nucleic acid-bound dyes in rats given the carcinogen N-methyl-4-aminoazobenzene. Cancer Research. 35: 844-50. PMID 1116139 |
0.502 |
|
| 1975 |
Lin JK, Schmall B, Sharpe ID, Miura I, Miller JA, Miller EC. N-substitution of carbon 8 in guanosine and deoxyguanosine by the carcinogen N-benzoyloxy-N-methyl-4-aminoazobenzene in vitro. Cancer Research. 35: 832-43. PMID 1116138 |
0.467 |
|
| 1975 |
Swenson DH, Miller JA, Miller EC. The reactivity and carcinogenicity of aflatoxin B1-2,3-dichloride, a model for the putative 2,3-oxide metabolite of aflatoxin B1. Cancer Research. 35: 3811-23. PMID 1104159 |
0.438 |
|
| 1975 |
Miller JA, Miller EC. Chemical and Radiation Carcinogenesis in Man and Experimental Animals12 Radiation Researchbiomedical, Chemical, and Physical Perspectives. 158-168. DOI: 10.1016/B978-0-12-523350-7.50020-1 |
0.404 |
|
| 1975 |
Kadlubar FF, Miller JA, Miller EC. The metabolic activation of N methyl 4 aminoazobenzene by rat liver Proceedings of the American Association For Cancer Research. 16: No. 56. |
0.322 |
|
| 1974 |
Miller EC, Butler BW, Fletcher TL, Miller JA. Methylmercapto-4-acetylaminostilbenes as products of the reaction of n-acetoxy-4-acetylaminostilbene with methionine and as degradation products of liver protein from rats given n-hydroxy-4-acetylaminostilbene. Cancer Research. 34: 2232-9. PMID 4843530 |
0.495 |
|
| 1974 |
Bartsch H, Dworkin M, Miller JA, Miller EC. Synthesis, estrogenic activity, and electrophilic reactivity of an N-acetoxy-N-acetamido analog of diethylstilbestrol. Journal of Medicinal Chemistry. 17: 386-9. PMID 4830536 DOI: 10.1002/Chin.197435202 |
0.522 |
|
| 1974 |
Swenson DH, Miller EC, Miller JA. Aflatoxin B1-2,3-oxide: evidence for its formation in rat liver in vivo and by human liver microsomes in vitro. Biochemical and Biophysical Research Communications. 60: 1036-43. PMID 4429559 DOI: 10.1016/0006-291X(74)90417-3 |
0.546 |
|
| 1973 |
Swenson DH, Miller JA, Miller EC. 2,3-Dihydro-2,3-dihydroxy-aflatoxin B1: an acid hydrolysis product of an RNA-aflatoxin B1 adduct formed by hamster and rat liver microsomes in vitro. Biochemical and Biophysical Research Communications. 53: 1260-7. PMID 4748819 DOI: 10.1016/0006-291X(73)90601-3 |
0.508 |
|
| 1973 |
Bartsch H, Dworkin C, Miller EC, Miller JA. Formation of electrophilic N-acetoxyarylamines in cytosoles from rat mammary gland and other tissues by transacetylation from the carcinogen N-hydroxy-4-acetylaminobiphenyl. Biochimica Et Biophysica Acta. 304: 42-55. PMID 4699998 DOI: 10.1016/0304-4165(73)90113-X |
0.568 |
|
| 1973 |
Borchert P, Wislocki PG, Miller JA, Miller EC. The metabolism of the naturally occurring hepatocarcinogen safrole to 1'-hydroxysafrole and the electrophilic reactivity of 1'-acetoxysafrole. Cancer Research. 33: 575-89. PMID 4689905 |
0.369 |
|
| 1973 |
Borchert P, Miller JA, Miller EC, Shires TK. 1'-Hydroxysafrole, a proximate carcinogenic metabolite of safrole in the rat and mouse. Cancer Research. 33: 590-600. PMID 4347718 |
0.436 |
|
| 1972 |
Stich HF, San RH, Miller JA, Miller EC. Various levels of DNA repair synthesis in xeroderma pigmentosum cells exposed to the carcinogens N-hydroxy and N-acetoxy-2-acetylaminofluorene. Nature: New Biology. 238: 9-10. PMID 18663834 DOI: 10.1038/Newbio238009A0 |
0.434 |
|
| 1972 |
Bartsch H, Miller JA, Miller EC. N-acetoxy-N-acetylaminoarenes and nitrosoarenes. One-electron non-enzymatic and enzymatic oxidation products of various carcinogenic aromatic acethydroxamic acids. Biochimica Et Biophysica Acta. 273: 40-51. PMID 5038286 DOI: 10.1016/0304-4165(72)90189-4 |
0.529 |
|
| 1972 |
Bartsch H, Dworkin M, Miller JA, Miller EC. Electrophilic N-acetoxyaminoarenes derived from carcinogenic N-hydroxy-N-acetylaminoarenes by enzymatic deacetylation and transacetylation in liver. Biochimica Et Biophysica Acta. 286: 272-98. PMID 4660457 DOI: 10.1016/0304-4165(72)90265-6 |
0.592 |
|
| 1972 |
Garner RC, Miller EC, Miller JA. Liver microsomal metabolism of aflatoxin B 1 to a reactive derivative toxic to Salmonella typhimurium TA 1530. Cancer Research. 32: 2058-66. PMID 4404160 |
0.439 |
|
| 1971 |
Enomoto M, Miller EC, Miller JA. Comparative carcinogenicity of 4-hydroxyaminoquinoline-1-oxide and its diacetyl derivative in mice and rats. Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine (New York, N.Y.). 136: 1206-10. PMID 5554466 DOI: 10.3181/00379727-136-35459 |
0.511 |
|
| 1971 |
Miller JA, Miller EC. Chemical carcinogenesis: mechanisms and approaches to its control. Journal of the National Cancer Institute. 47: V-XIV. PMID 5157587 |
0.323 |
|
| 1971 |
Garner RC, Miller EC, Miller JA, Garner JV, Hanson RS. Formation of a factor lethal for S. typhimurium TA1530 and TA1531 on incubation of aflatoxin B 1 with rat liver microsomes. Biochemical and Biophysical Research Communications. 45: 774-80. PMID 4399636 DOI: 10.1016/0006-291X(71)90484-0 |
0.526 |
|
| 1970 |
Scribner JD, Miller JA, Miller EC. Nucleophilic substitution on carcinogenic N-acetoxy-N-arylacetamides. Cancer Research. 30: 1570-9. PMID 5457931 |
0.45 |
|
| 1970 |
DeBaun JR, Miller EC, Miller JA. N-hydroxy-2-acetylaminofluorene sulfotransferase: its probable role in carcinogenesis and in protein-(methion-S-yl) binding in rat liver. Cancer Research. 30: 577-95. PMID 5425283 |
0.485 |
|
| 1970 |
DeBaun JR, Smith JY, Miller EC, Miller JA. Reactivity in vivo of the carcinogen N-hydroxy-2-acetylaminofluorene: increase by sulfate ion. Science (New York, N.Y.). 167: 184-6. PMID 5409643 DOI: 10.1126/Science.167.3915.184 |
0.585 |
|
| 1970 |
Maher VM, Miller JA, Miller EC, Summers WC. Mutations and loss of transforming activity of Bacillus subtilis DNA after reaction with esters of carcinogenic N-hydroxy aromatic amides. Cancer Research. 30: 1473-80. PMID 4987694 |
0.437 |
|
| 1970 |
SCRIBNER JD, MILLER JA, MILLER EC. ChemInform Abstract: NUCLEOPHILE SUBSTITUTION AN CARCINOGENEN N-ACETOXY-N-ARYLACETAMIDEN Chemischer Informationsdienst. Organische Chemie. 1: no-no. DOI: 10.1002/Chin.197049300 |
0.51 |
|
| 1969 |
Lin JK, Miller JA, Miller EC. Studies on structures of polar dyes derived from the liver proteins of rats fed N-methyl-4-aminoazobenzene. 3. Tyrosine and homocysteine sulfoxide polar dyes. Biochemistry. 8: 1573-82. PMID 5805296 DOI: 10.1021/Bi00832A037 |
0.455 |
|
| 1969 |
Miller JA, Miller EC. The metabolic activation of carcinogenic aromatic amines and amides. Progress in Experimental Tumor Research. 11: 273-301. PMID 4888944 DOI: 10.1159/000391399 |
0.401 |
|
| 1969 |
Miller EC, Miller JA. STUDIES ON THE MECHANISM OF ACTIVATION OF AROMATIC AMINE AND AMIDE CARCINOGENS TO ULTIMATE CARCINOGENIC ELECTROPHILIC REACTANTS Annals of the New York Academy of Sciences. 163: 731-750. DOI: 10.1111/J.1749-6632.1969.Tb24891.X |
0.486 |
|
| 1968 |
Enomoto M, Sato K, Miller EC, Miller JA. Reactivity of the diacetyl derivative of the carcinogen 4-hydroxyaminoquinoline-1-oxide with DNA, RNA, and other nucleophiles. Life Sciences. 7: 1025-32. PMID 5712274 DOI: 10.1016/0024-3205(68)90138-0 |
0.467 |
|
| 1968 |
DeBaun JR, Rowley JY, Miller EC, Miller JA. Sulfotransferase activation of N-hydroxy-2-acetylaminofluorene in rodent livers susceptible and resistant to this carcinogen. Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine (New York, N.Y.). 129: 268-73. PMID 5697914 DOI: 10.3181/00379727-129-33301 |
0.528 |
|
| 1968 |
Lin JK, Miller JA, Miller EC. Studies on structures of polar dyes derived from the liver proteins of rats fed N-methyl-4-aminoazobenzene. II. Identity of synthetic 3-(homocystein-S-yl)-N-methyl-4-aminoazobenzene with the major polar dye P2b. Biochemistry. 7: 1889-95. PMID 4297057 DOI: 10.1021/Bi00845A037 |
0.474 |
|
| 1967 |
Lin JK, Miller JA, Miller EC. Studies on the structures of polar dyes from liver proteins of rats fed N-methyl-4-aminoazobenzene: I. Retention of the methyl group. Biochemical and Biophysical Research Communications. 28: 1040-6. PMID 6064583 DOI: 10.1016/0006-291X(67)90087-3 |
0.528 |
|
| 1967 |
Kriek E, Miller JA, Juhl U, Miller EC. 8-(N-2-fluorenylacetamido)guanosine, an arylamidation reaction product of guanosine and the carcinogen N-acetoxy-N-2-fluorenylacetamide in neutral solution. Biochemistry. 6: 177-82. PMID 6030315 DOI: 10.1021/Bi00853A029 |
0.441 |
|
| 1967 |
Lotlikar PD, Enomoto M, Miller JA, Miller EC. Species variations in the N- and ring-hydroxylation of 2-acetylaminofluorene and effects of 3-methylcholanthrene pretreatment. Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine (New York, N.Y.). 125: 341-6. PMID 6028542 DOI: 10.3181/00379727-125-32086 |
0.566 |
|
| 1967 |
Miller EC, Miller JA. Low carcinogenicity of the K-region epoxides of 7-methylbenz(a)-anthracene and benz(a)anthracene in the mouse and rat. Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine (New York, N.Y.). 124: 915-9. PMID 6023434 DOI: 10.3181/00379727-124-31885 |
0.485 |
|
| 1967 |
Lotlikar PD, Miller EC, Miller JA, Halver JE. Metabolism of the carcinogen 2-acetylaminofluorene by rainbow trout. Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine (New York, N.Y.). 124: 160-3. PMID 4381126 DOI: 10.3181/00379727-124-31690 |
0.434 |
|
| 1966 |
Miller EC, Juhl U, Miller JA. Nucleic acid guanine: reaction with the carcinogen N-acetoxy-2-acetylaminofluorene. Science (New York, N.Y.). 153: 1125-7. PMID 5918575 DOI: 10.1126/Science.153.3740.1125 |
0.534 |
|
| 1966 |
Lotlikar PD, Scribner JD, Miller JA, Miller EC. Reaction of esters of aromatic -hydroxy amines and amides with methionine : A model for binding of amine carcinogens to protein Life Sciences. 5: 1263-1269. DOI: 10.1016/0024-3205(66)90026-9 |
0.549 |
|
| 1965 |
MILLER JA, MILLER EC. METABOLISM OF DRUGS IN RELATION OF CARCINOGENICITY. Annals of the New York Academy of Sciences. 123: 125-40. PMID 14329197 DOI: 10.1111/J.1749-6632.1965.Tb12250.X |
0.465 |
|
| 1965 |
Miller EC, McKechnie D, Poirier MM, Miller JA. Inhibition of amino acid incorporation in vitro by metabolites of 2-acetylaminofluorene and by certain nitroso compounds. Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine (New York, N.Y.). 120: 538-41. PMID 5856439 DOI: 10.3181/00379727-120-30583 |
0.524 |
|
| 1965 |
Scribner JD, Miller JA, Miller EC. 3-methylmercapto-N-methyl-4-aminoazobenzene: an alkaline-degradation product of a labile protein-bound dye in the livers of rats fed N,N-dimethyl-4-aminoazobenzene. Biochemical and Biophysical Research Communications. 20: 560-5. PMID 4955463 DOI: 10.1016/0006-291X(65)90435-3 |
0.565 |
|
| 1960 |
MILLER EC, MILLER JA. A mechanism of orthol-hydroxylation of aromatic amines in vivo. Biochimica Et Biophysica Acta. 40: 380-2. PMID 13853959 DOI: 10.1016/0006-3002(60)91376-7 |
0.452 |
|
| 1959 |
HARTMANN HA, MILLER EC, MILLER JA. Periarteritis in rats given single injection of 4'-fluoro-10-methyl-1,2-benzanthracene. Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine (New York, N.Y.). 101: 626-9. PMID 14400170 DOI: 10.3181/00379727-101-25040 |
0.46 |
|
| 1959 |
MILLER EC, MILLER JA. Biochemistry of carcinogenesis. Annual Review of Biochemistry. 28: 291-320. PMID 13853960 DOI: 10.1146/annurev.bi.28.070159.001451 |
0.377 |
|
| 1959 |
GELBOIN HV, MILLER JA, MILLER EC. The in vitro formation of protein-bound derivatives of aminoazo dyes by rat liver preparations. Cancer Research. 19: 975-85. PMID 13827171 |
0.608 |
|
| 1958 |
GELBOIN HV, MILLER JA, MILLER EC. Studies on hepatic protein-bound dye formation in rats given single large doses of 3'methyl-4-dimethylaminoazobenzene. Cancer Research. 18: 608-17. PMID 13547059 |
0.592 |
|
| 1958 |
GELBOIN HV, MILLER JA, MILLER EC. The formation in vitro of proteinbound derivatives of aminoazo dyes by rat liver and its enhancement by benzpyrene pretreatment. Biochimica Et Biophysica Acta. 27: 655-6. PMID 13535659 |
0.61 |
|
| 1955 |
Miller EC, Miller JA. Biochemical investigations on hepatic carcinogenesis. Journal of the National Cancer Institute. 15: 1571-1590. DOI: 10.1093/Jnci/15.Supplement_5.1571 |
0.469 |
|
| 1953 |
MILLER JA, MILLER EC. The carcinogenic aminoazo dyes. Advances in Cancer Research. 1: 339-96. PMID 13057708 DOI: 10.1016/S0065-230X(08)60007-X |
0.466 |
|
| 1952 |
Sandin RB, Melby R, Hay AS, Jones RN, Miller EC, Miller JA. Ultraviolet Spectra and Carcinogenic Activities of Some Fluorene and Biphenyl Derivatives Journal of the American Chemical Society. 74: 5073-5075. DOI: 10.1021/Ja01140A023 |
0.455 |
|
| 1949 |
PRICE JM, MILLER EC, MILLER JA. Intracellular distribution of vitamin B6 in rat and mouse livers and induced rat liver tumors. Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine (New York, N.Y.). 71: 575-8. PMID 18139816 DOI: 10.3181/00379727-71-17261 |
0.503 |
|
| 1948 |
MILLER JA, SAPP RW, MILLER EC. The absorption spectra of certain carcinogenic aminoazo dyes and the protein-bound derivatives formed from these dyes in vivo. Journal of the American Chemical Society. 70: 3458-63. PMID 18891891 DOI: 10.1021/JA01190A072 |
0.364 |
|
| 1946 |
MILLER EC, BAUMANN CA. The carcinogenicity of p-monomethylaminoazobenzene in various diets and the activity of this dye relative to p-dimethylaminoazobenzene. Cancer Research. 6: 289-95. PMID 20983249 |
0.472 |
|
| 1945 |
MILLER EC, BAUMANN CA, RUSCH HP. Certain effects of dietery pyridoxine and casein on the carcinogenicity of P-dime-thylaminoazobenzene. Cancer Research. 5: 713-6. PMID 21003398 |
0.46 |
|
| 1944 |
Miller EC, Baumann CA. The Maintenance of Adult Rats on Diets Low in Certain B Vitamins The Journal of Nutrition. 27: 319-328. DOI: 10.1093/jn/27.4.319 |
0.488 |
|
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