Robert Hilgraf - Publications

Affiliations: 
Medicinal Chemistry Broad Institute of Harvard and MIT 

4/12 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Radke JB, Carey KL, Shaw S, Metkar S, Mulrooney C, Gale JP, Bittker JA, Hilgraf R, Comer E, Schreiber SL, Virgin HW, Perez JR, Sibley LD. High throughput screen identifies IFN-γ-dependent inhibitors of Toxoplasma gondii growth. Acs Infectious Diseases. PMID 30058798 DOI: 10.1021/Acsinfecdis.8B00135  0.525
2005 Himo F, Lovell T, Hilgraf R, Rostovtsev VV, Noodleman L, Sharpless KB, Fokin VV. Copper(I)-catalyzed synthesis of azoles. DFT study predicts unprecedented reactivity and intermediates. Journal of the American Chemical Society. 127: 210-6. PMID 15631470 DOI: 10.1021/Ja0471525  0.637
2004 Chan TR, Hilgraf R, Sharpless KB, Fokin VV. Polytriazoles as copper(I)-stabilizing ligands in catalysis. Organic Letters. 6: 2853-5. PMID 15330631 DOI: 10.1021/Ol0493094  0.596
2003 Wang Q, Chan TR, Hilgraf R, Fokin VV, Sharpless KB, Finn MG. Bioconjugation by copper(I)-catalyzed azide-alkyne [3 + 2] cycloaddition. Journal of the American Chemical Society. 125: 3192-3. PMID 12630856 DOI: 10.1021/Ja021381E  0.561
Low-probability matches (unlikely to be authored by this person)
2021 McKinney DC, McMillan BJ, Ranaghan MJ, Moroco JA, Brousseau M, Mullin-Bernstein Z, O'Keefe M, McCarren P, Mesleh MF, Mulvaney KM, Robinson F, Singh R, Bajrami B, Wagner FF, Hilgraf R, et al. Discovery of a First-in-Class Inhibitor of the PRMT5-Substrate Adaptor Interaction. Journal of Medicinal Chemistry. PMID 34342224 DOI: 10.1021/acs.jmedchem.1c00507  0.171
2012 Zimmermann N, Hilgraf R, Lehmann L, Ibarra D, Francke W. Stereoselective synthesis of trans-fused iridoid lactones and their identification in the parasitoid wasp Alloxysta victrix, Part I: Dihydronepetalactones. Beilstein Journal of Organic Chemistry. 8: 1246-55. PMID 23019455 DOI: 10.3762/Bjoc.8.140  0.134
2021 Nagy MA, Hilgraf R, Mortensen DS, Elsner J, Norris S, Tikhe J, Yoon W, Paisner D, Delgado M, Erdman P, Haelewyn J, Khambatta G, Xu L, Romanow WJ, Condroski K, et al. Discovery of the c-Jun N-Terminal Kinase Inhibitor . Journal of Medicinal Chemistry. PMID 34894681 DOI: 10.1021/acs.jmedchem.1c01716  0.128
2010 Zhu D, Hensel J, Hilgraf R, Abbasian M, Pornillos O, Deyanat-Yazdi G, Hua XH, Cox S. Inhibition of protein kinase CK2 expression and activity blocks tumor cell growth. Molecular and Cellular Biochemistry. 333: 159-67. PMID 19629644 DOI: 10.1007/S11010-009-0216-0  0.118
2012 Hilgraf R, Zimmermann N, Lehmann L, Tröger A, Francke W. Stereoselective synthesis of trans-fused iridoid lactones and their identification in the parasitoid wasp Alloxysta victrix, Part II: Iridomyrmecins. Beilstein Journal of Organic Chemistry. 8: 1256-64. PMID 23019456 DOI: 10.3762/Bjoc.8.141  0.096
2012 Plantevin Krenitsky V, Nadolny L, Delgado M, Ayala L, Clareen SS, Hilgraf R, Albers R, Hegde S, D'Sidocky N, Sapienza J, Wright J, McCarrick M, Bahmanyar S, Chamberlain P, Delker SL, et al. Discovery of CC-930, an orally active anti-fibrotic JNK inhibitor. Bioorganic & Medicinal Chemistry Letters. 22: 1433-8. PMID 22244937 DOI: 10.1016/J.Bmcl.2011.12.027  0.095
2012 Krenitsky VP, Delgado M, Nadolny L, Sahasrabudhe K, Ayala L, Clareen SS, Hilgraf R, Albers R, Kois A, Hughes K, Wright J, Nowakowski J, Sudbeck E, Ghosh S, Bahmanyar S, et al. Aminopurine based JNK inhibitors for the prevention of ischemia reperfusion injury. Bioorganic & Medicinal Chemistry Letters. 22: 1427-32. PMID 22226655 DOI: 10.1016/J.Bmcl.2011.12.028  0.066
2012 Packard GK, Papa P, Riggs JR, Erdman P, Tehrani L, Robinson D, Harris R, Shevlin G, Perrin-Ninkovic S, Hilgraf R, McCarrick MA, Tran T, Fleming Y, Bai A, Richardson S, et al. Discovery and optimization of thieno[2,3-d]pyrimidines as B-Raf inhibitors. Bioorganic & Medicinal Chemistry Letters. 22: 747-52. PMID 22137342 DOI: 10.1016/j.bmcl.2011.03.006  0.053
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