| Year |
Citation |
Score |
| 2010 |
DANIEL D, MIDDLETON R, HENRY HL, OKAMURA WH. ChemInform Abstract: Studies of Vitamin D (Calciferol) and Its Analogues. Part 50. Inhibitors of 25-Hydroxyvitamin D3-1α-Hydroxylase: A-Ring Oxa Analogues of 25-Hydroxyvitamin D3. Cheminform. 28: no-no. DOI: 10.1002/chin.199702196 |
0.48 |
|
| 2010 |
FERNANDEZ S, FERRERO M, GOTOR V, OKAMURA WH. ChemInform Abstract: Studies of Vitamin D and Its Analogues. Part 49. Selective Acylation of A-Ring Precursors of Vitamin D Using Enzymes in Organic Solvents. Cheminform. 27: no-no. DOI: 10.1002/chin.199606075 |
0.446 |
|
| 2010 |
MAYNARD DF, TRANKLE WG, NORMAN AW, OKAMURA WH. ChemInform Abstract: Vitamin D (Calciferol) and Its Analogues. Part 48. 14-Epi Stereoisomers of 25-Hydroxy- and 1α,25-Dihydroxyvitamin D3: Synthesis, Isomerization to Previtamins, and Biological Studies. Cheminform. 25: no-no. DOI: 10.1002/chin.199451284 |
0.484 |
|
| 2010 |
VANALSTYNE EM, NORMAN AW, OKAMURA WH. ChemInform Abstract: Vitamin D (Calciferol) and Its Analogues. Part 47. 7,8-cis Geometric Isomers of the Steroid Hormone 1α,25-Dihydroxyvitamin D3. Cheminform. 25: no-no. DOI: 10.1002/chin.199451281 |
0.461 |
|
| 2010 |
CRAIG AS, NORMAN AW, OKAMURA WH. ChemInform Abstract: Studies of Vitamin D (Calciferol) and Its Analogues. Part 43. Two Novel Allenic Side Chain Analogues of 1α,25-Dihydroxyvitamin D3. Cheminform. 23: no-no. DOI: 10.1002/chin.199252282 |
0.462 |
|
| 2010 |
CURTIN ML, OKAMURA WH. ChemInform Abstract: Studies on Vitamin D (Calciferol) and Its Analogues. Part 40. 1α, 25-Dihydroxyprevitamin D3: Synthesis of the 9,14,19,19,19- Pentadeuterio Derivative and a Kinetic Study of Its (1,7)-Sigmatropic Shift to 1α,25-Dihydroxyvitamin D3. Cheminform. 22: no-no. DOI: 10.1002/chin.199150235 |
0.454 |
|
| 2010 |
ENAS JD, SHEN G, OKAMURA WH. ChemInform Abstract: Vitamin D (Calciferol) and Its Analogues. Part 38. (1,7)-Sigmatropic Hydrogen Shifts of A-Norvitamin D Analogues: Ring Size and Substituent Effects on the Previtamin D-Vitamin D Equilibrium. Cheminform. 22: no-no. DOI: 10.1002/chin.199134246 |
0.484 |
|
| 2010 |
ENAS JD, PALENZUELA JA, OKAMURA WH. ChemInform Abstract: Studies on Vitamin D (Calciferol) and Its Analogues. Part 37. A-Homo- 11-hydroxy-3-deoxyvitamin D: Ring Size and π-Facial Selectivity Effects on the (1,7)-Sigmatropic Hydrogen Shift of Previtamin D to Vitamin D. Cheminform. 22: no-no. DOI: 10.1002/chin.199126272 |
0.478 |
|
| 2005 |
Collins ED, Bishop JE, Bula CM, Acevedo A, Okamura WH, Norman AW. Effect of 25-hydroxyl group orientation on biological activity and binding to the 1alpha,25-dihydroxy vitamin D3 receptor. The Journal of Steroid Biochemistry and Molecular Biology. 94: 279-88. PMID 15857747 DOI: 10.1016/J.Jsbmb.2004.11.013 |
0.514 |
|
| 2003 |
Norman AW, Mizwicki MT, Okamura WH. Ligand structure-function relationships in the vitamin D endocrine system from the perspective of drug development (including cancer treatment). Recent Results in Cancer Research. Fortschritte Der Krebsforschung. ProgrèS Dans Les Recherches Sur Le Cancer. 164: 55-82. PMID 12899514 |
0.409 |
|
| 2002 |
Norman AW, Okamura WH, Bishop JE, Henry HL. Update on biological actions of 1alpha,25(OH)2-vitamin D3 (rapid effects) and 24R,25(OH)2-vitamin D3. Molecular and Cellular Endocrinology. 197: 1-13. PMID 12431790 DOI: 10.1016/S0303-7207(02)00273-3 |
0.539 |
|
| 2002 |
Shi H, Norman AW, Okamura WH, Sen A, Zemel MB. 1alpha,25-dihydroxyvitamin D3 inhibits uncoupling protein 2 expression in human adipocytes. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 16: 1808-10. PMID 12223452 DOI: 10.1096/Fj.02-0255Fje |
0.478 |
|
| 2002 |
Norman AW, Bishop JE, Bula CM, Olivera CJ, Mizwicki MT, Zanello LP, Ishida H, Okamura WH. Molecular tools for study of genomic and rapid signal transduction responses initiated by 1 alpha,25(OH)(2)-vitamin D(3). Steroids. 67: 457-66. PMID 11960621 DOI: 10.1016/S0039-128X(01)00167-2 |
0.505 |
|
| 2002 |
Okamura WH, Zhu GD, Hill DK, Thomas RJ, Ringe K, Borchardt DB, Norman AW, Mueller LJ. Synthesis and NMR studies of (13)C-labeled vitamin D metabolites. The Journal of Organic Chemistry. 67: 1637-50. PMID 11871897 DOI: 10.1021/Jo011096Y |
0.363 |
|
| 2002 |
Hayashi R, Fernández S, Okamura WH. An 8pi electron electrocyclization leading to a 9,19-methano-bridged analogue of 1 alpha,25-dihydroxyvitamin D3. Organic Letters. 4: 851-4. PMID 11869144 DOI: 10.1021/Ol020017H |
0.661 |
|
| 2001 |
Shi H, Norman AW, Okamura WH, Sen A, Zemel MB. 1alpha,25-Dihydroxyvitamin D3 modulates human adipocyte metabolism via nongenomic action. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 15: 2751-3. PMID 11606486 DOI: 10.1096/Fj.01-0584Fje |
0.472 |
|
| 2001 |
Norman AW, Ishizuka S, Okamura WH. Ligands for the vitamin D endocrine system: different shapes function as agonists and antagonists for genomic and rapid response receptors or as a ligand for the plasma vitamin D binding protein. The Journal of Steroid Biochemistry and Molecular Biology. 76: 49-59. PMID 11384863 DOI: 10.1016/S0960-0760(00)00145-X |
0.55 |
|
| 2001 |
Reddy GS, Muralidharan KR, Okamura WH, Tserng KY, McLane JA. Metabolism of 1alpha,25-dihydroxyvitamin D(3) and its C-3 epimer 1alpha,25-dihydroxy-3-epi-vitamin D(3) in neonatal human keratinocytes. Steroids. 66: 441-50. PMID 11179753 DOI: 10.1016/S0039-128X(00)00228-2 |
0.507 |
|
| 2001 |
Okamura WH, Do S, Kim H, Jeganathan S, Vu T, Zhu GD, Norman AW. Conformationally restricted mimics of vitamin D rotamers. Steroids. 66: 239-47. PMID 11179731 DOI: 10.1016/S0039-128X(00)00147-1 |
0.51 |
|
| 2001 |
Norman AW, Henry HL, Bishop JE, Song XD, Bula C, Okamura WH. Different shapes of the steroid hormone 1alpha,25(OH)(2)-vitamin D(3) act as agonists for two different receptors in the vitamin D endocrine system to mediate genomic and rapid responses. Steroids. 66: 147-58. PMID 11179722 DOI: 10.1016/S0039-128X(00)00165-3 |
0.549 |
|
| 2000 |
Norman AW, Manchand PS, Uskokovic MR, Okamura WH, Takeuchi JA, Bishop JE, Hisatake JI, Koeffler HP, Peleg S. Characterization of a novel analogue of 1alpha,25(OH)(2)-vitamin D(3) with two side chains: interaction with its nuclear receptor and cellular actions. Journal of Medicinal Chemistry. 43: 2719-30. PMID 10893309 DOI: 10.1021/jm0000160 |
0.414 |
|
| 2000 |
Tan ES, Tham FS, Okamura WH. Vitamin D1 Chemical Communications. 2345-2346. |
0.454 |
|
| 1999 |
Norman AW, Adams D, Collins ED, Okamura WH, Fletterick RJ. Three-dimensional model of the ligand binding domain of the nuclear receptor for 1alpha,25-dihydroxy-vitamin D(3). Journal of Cellular Biochemistry. 74: 323-33. PMID 10412035 DOI: 10.1002/(Sici)1097-4644(19990901)74:3<323::Aid-Jcb2>3.0.Co;2-V |
0.437 |
|
| 1999 |
Norman AW, Song X, Zanello L, Bula C, Okamura WH. Rapid and genomic biological responses are mediated by different shapes of the agonist steroid hormone, 1alpha,25(OH)2vitamin D3. Steroids. 64: 120-8. PMID 10323680 DOI: 10.1016/S0039-128X(98)00091-9 |
0.455 |
|
| 1999 |
Siu-Caldera ML, Sekimoto H, Weiskopf A, Vouros P, Muralidharan KR, Okamura WH, Bishop J, Norman AW, Uskokovi? MR, Schuster I, Reddy GS. Production of 1alpha,25-dihydroxy-3-epi-vitamin D3 in two rat osteosarcoma cell lines (UMR 106 and ROS 17/2.8): existence of the C-3 epimerization pathway in ROS 17/2.8 cells in which the C-24 oxidation pathway is not expressed. Bone. 24: 457-63. PMID 10321905 DOI: 10.1016/S8756-3282(99)00019-8 |
0.446 |
|
| 1999 |
Sekimoto H, Siu-Caldera ML, Weiskopf A, Vouros P, Muralidharan KR, Okamura WH, Uskokovic MR, Reddy GS. 1alpha,25-dihydroxy-3-epi-vitamin D3: in vivo metabolite of 1alpha,25-dihydroxyvitamin D3 in rats. Febs Letters. 448: 278-82. PMID 10218492 DOI: 10.1016/S0014-5793(99)00377-4 |
0.516 |
|
| 1999 |
Brown AJ, Ritter C, Slatopolsky E, Muralidharan KR, Okamura WH, Reddy GS. 1Alpha,25-dihydroxy-3-epi-vitamin D3, a natural metabolite of 1alpha,25-dihydroxyvitamin D3, is a potent suppressor of parathyroid hormone secretion. Journal of Cellular Biochemistry. 73: 106-13. PMID 10088729 DOI: 10.1002/(Sici)1097-4644(19990401)73:1<106::Aid-Jcb12>3.0.Co;2-Q |
0.5 |
|
| 1998 |
Song X, Bishop JE, Okamura WH, Norman AW. Stimulation of phosphorylation of mitogen-activated protein kinase by 1alpha,25-dihydroxyvitamin D3 in promyelocytic NB4 leukemia cells: a structure-function study. Endocrinology. 139: 457-65. PMID 9449611 DOI: 10.1210/Endo.139.2.5747 |
0.492 |
|
| 1997 |
Muralidharan KR, Rowland-Goldsmith M, Lee AS, Park G, Norman AW, Henry HL, Okamura WH. Inhibitors of 25-hydroxyvitamin D3-1alpha-hydroxylase: thiavitamin D analogs and biological evaluation. The Journal of Steroid Biochemistry and Molecular Biology. 62: 73-8. PMID 9366500 DOI: 10.1016/S0960-0760(97)00015-0 |
0.519 |
|
| 1997 |
Norman AW, Okamura WH, Hammond MW, Bishop JE, Dormanen MC, Bouillon R, van Baelen H, Ridall AL, Daane E, Khoury R, Farach-Carson MC. Comparison of 6-s-cis- and 6-s-trans-locked analogs of 1alpha,25-dihydroxyvitamin D3 indicates that the 6-s-cis conformation is preferred for rapid nongenomic biological responses and that neither 6-s-cis- nor 6-s-trans-locked analogs are preferred for genomic biological responses. Molecular Endocrinology (Baltimore, Md.). 11: 1518-31. PMID 9280067 DOI: 10.1210/Mend.11.10.9993 |
0.467 |
|
| 1996 |
Norman AW, Bishop JE, Collins ED, Seo EG, Satchell DP, Dormanen MC, Zanello SB, Farach-Carson MC, Bouillon R, Okamura WH. Differing shapes of 1 alpha,25-dihydroxyvitamin D3 function as ligands for the D-binding protein, nuclear receptor and membrane receptor: a status report. The Journal of Steroid Biochemistry and Molecular Biology. 56: 13-22. PMID 8603033 DOI: 10.1016/0960-0760(95)00219-7 |
0.517 |
|
| 1996 |
Daniel D, Middleton R, Henry HL, Okamura WH. Inhibitors of 25-hydroxyvitamin D3-1α-hydroxylase: A-ring oxa analogs of 25-hydroxyvitamin D3 1 Journal of Organic Chemistry. 61: 5617-5625. DOI: 10.1021/Jo960498G |
0.435 |
|
| 1995 |
Bouillon R, Okamura WH, Norman AW. Structure-function relationships in the vitamin D endocrine system. Endocrine Reviews. 16: 200-57. PMID 7781594 DOI: 10.1210/Edrv-16-2-200 |
0.53 |
|
| 1995 |
Okamura WH, Midland MM, Hammond MW, Abd Rahman N, Dormanen MC, Nemere I, Norman AW. Chemistry and conformation of vitamin D molecules. The Journal of Steroid Biochemistry and Molecular Biology. 53: 603-13. PMID 7626517 DOI: 10.1016/0960-0760(95)00107-B |
0.385 |
|
| 1995 |
Okamura WH, Midland MM, Norman AW, Hammond MW, Dormanen MC, Nemere I. Biochemical significance of the 6-s-cis conformation of the steroid hormone 1 alpha,25-dihydroxyvitamin D3 based on the provitamin D skeleton. Annals of the New York Academy of Sciences. 761: 344-8. PMID 7625732 DOI: 10.1111/J.1749-6632.1995.Tb31389.X |
0.512 |
|
| 1995 |
Fernandez S, Ferrero M, Gotor V, Okamura WH. Selective acylation of A-ring precursors of vitamin D using enzymes in organic solvents Journal of Organic Chemistry. 60: 6057-6061. DOI: 10.1021/Jo00124A014 |
0.469 |
|
| 1995 |
Zhu GD, Okamura WH. Synthesis of vitamin D (Calciferol) Chemical Reviews. 95: 1877-1952. |
0.474 |
|
| 1994 |
Dormanen MC, Bishop JE, Hammond MW, Okamura WH, Nemere I, Norman AW. Nonnuclear effects of the steroid hormone 1 alpha,25(OH)2-vitamin D3: analogs are able to functionally differentiate between nuclear and membrane receptors. Biochemical and Biophysical Research Communications. 201: 394-401. PMID 8198601 DOI: 10.1006/Bbrc.1994.1714 |
0.465 |
|
| 1994 |
Nemere I, Dormanen MC, Hammond MW, Okamura WH, Norman AW. Identification of a specific binding protein for 1 alpha,25-dihydroxyvitamin D3 in basal-lateral membranes of chick intestinal epithelium and relationship to transcaltachia. The Journal of Biological Chemistry. 269: 23750-6. PMID 8089147 |
0.44 |
|
| 1994 |
Elstner E, Lee YY, Hashiya M, Pakkala S, Binderup L, Norman AW, Okamura WH, Koeffler HP. 1 alpha,25-Dihydroxy-20-epi-vitamin D3: an extraordinarily potent inhibitor of leukemic cell growth in vitro. Blood. 84: 1960-7. PMID 8080998 |
0.385 |
|
| 1994 |
Maynard DF, Trankle WG, Norman AW, Okamura WH. 14-epi stereoisomers of 25-hydroxy- and 1 alpha,25-dihydroxyvitamin D3: synthesis, isomerization to previtamins, and biological studies. Journal of Medicinal Chemistry. 37: 2387-93. PMID 8057286 DOI: 10.1021/Jm00041A017 |
0.526 |
|
| 1994 |
Bishop JE, Collins ED, Okamura WH, Norman AW. Profile of ligand specificity of the vitamin D binding protein for 1 alpha,25-dihydroxyvitamin D3 and its analogs. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 9: 1277-88. PMID 7976510 DOI: 10.1002/Jbmr.5650090818 |
0.444 |
|
| 1994 |
VanAlstyne EM, Norman AW, Okamura WH. 7,8-Cis Geometric Isomers of the Steroid Hormone 1.alpha.,25-Dihydroxyvitamin D3 Journal of the American Chemical Society. 116: 6207-6216. DOI: 10.1021/Ja00093A021 |
0.464 |
|
| 1994 |
VanAlstyne EM, Norman AW, Okamura WH. 7,8-Cis geometric isomers of the steroid hormone 1α,25-dihydroxyvitamin D3 Journal of the American Chemical Society. 116: 6207-6216. |
0.329 |
|
| 1993 |
Norman AW, Bouillon R, Farach-Carson MC, Bishop JE, Zhou LX, Nemere I, Zhao J, Muralidharan KR, Okamura WH. Demonstration that 1 beta,25-dihydroxyvitamin D3 is an antagonist of the nongenomic but not genomic biological responses and biological profile of the three A-ring diastereomers of 1 alpha,25-dihydroxyvitamin D3. The Journal of Biological Chemistry. 268: 20022-30. PMID 8397195 |
0.424 |
|
| 1993 |
Norman AW, Sergeev IN, Bishop JE, Okamura WH. Selective biological response by target organs (intestine, kidney, and bone) to 1,25-dihydroxyvitamin D3 and two analogues. Cancer Research. 53: 3935-42. PMID 8395333 |
0.414 |
|
| 1993 |
Norman AW, Okamura WH, Farach-Carson MC, Allewaert K, Branisteanu D, Nemere I, Muralidharan KR, Bouillon R. Structure-function studies of 1,25-dihydroxyvitamin D3 and the vitamin D endocrine system. 1,25-dihydroxy-pentadeuterio-previtamin D3 (as a 6-s-cis analog) stimulates nongenomic but not genomic biological responses. The Journal of Biological Chemistry. 268: 13811-9. PMID 8390978 |
0.452 |
|
| 1993 |
Muralidharan KR, De Lera AR, Isaeff SD, Norman AW, Okamura WH. Studies of vitamin D (calciferol) and its analogs. 45. Studies on the A-ring diastereomers of 1.alpha.,25-dihydroxyvitamin D3 The Journal of Organic Chemistry. 58: 1895-1899. DOI: 10.1021/Jo00059A048 |
0.489 |
|
| 1993 |
Okamura WH, Elnagar HY, Ruther M, Dobreff S. Studies of vitamin D (calciferol) and its analogs. 44. Thermal [1,7]-sigmatropic shift of previtamin D3 to vitamin D3: synthesis and study of pentadeuterio derivatives The Journal of Organic Chemistry. 58: 600-610. DOI: 10.1021/Jo00055A011 |
0.568 |
|
| 1993 |
Midland MM, Plumet J, Okamura WH. Effect of C2O stereochemistry on the conformational profile of the side chains of vitamin D analogs. Bioorganic and Medicinal Chemistry Letters. 3: 1799-1804. DOI: 10.1016/S0960-894X(00)80108-0 |
0.433 |
|
| 1993 |
Okamura WH, Elnagar HY, Ruther M, Dobreff S. Thermal [1,7]-sigmatropic shift of previtamin D3 to vitamin D3: Synthesis and study of pentadeuterio derivatives Journal of Organic Chemistry. 58: 600-610. |
0.484 |
|
| 1993 |
Muralidharan KR, De Lera AR, Isaeff SD, Norman AW, Okamura WH. Studies on the A-ring diastereomers of 1α,25-dihydroxyvitamin D3 Journal of Organic Chemistry. 58: 1895-1899. |
0.369 |
|
| 1992 |
Okamura WH, Palenzuela JA, Plumet J, Midland MM. Vitamin D: structure-function analyses and the design of analogs. Journal of Cellular Biochemistry. 49: 10-8. PMID 1644848 DOI: 10.1002/jcb.240490104 |
0.377 |
|
| 1992 |
Norman AW, Nemere I, Muralidharan KR, Okamura WH. 1 beta, 25 (OH)2-vitamin D3 is an antagonist of 1 alpha,25 (OH)2-vitamin D3 stimulated transcaltachia (the rapid hormonal stimulation of intestinal calcium transport). Biochemical and Biophysical Research Communications. 189: 1450-6. PMID 1336368 DOI: 10.1016/0006-291X(92)90237-F |
0.524 |
|
| 1992 |
Craig AS, Norman AW, Okamura WH. Studies of vitamin D (calciferol) and its analogs. 43. Two novel allenic side chain analogs of 1.alpha.,25-dihydroxyvitamin D3 The Journal of Organic Chemistry. 57: 4374-4380. DOI: 10.1021/Jo00042A013 |
0.529 |
|
| 1992 |
Lee AS, Norman AW, Okamura WH. Studies of vitamin D (calciferol) and its analogs. 42. 3-Deoxy-3-thia-1.alpha.,25-dihydroxyvitamin D3 and its 1.beta.-epimer: synthesis and biological evaluation The Journal of Organic Chemistry. 57: 3846-3854. DOI: 10.1021/Jo00040A025 |
0.535 |
|
| 1992 |
Maynard DF, Norman AW, Okamura WH. Studies of vitamin D (calciferol) and its analogs. 41. 18-Substituted derivatives of vitamin D: 18-acetoxy-1.alpha.,25-dihydroxyvitamin D3 and related analogs The Journal of Organic Chemistry. 57: 3214-3217. DOI: 10.1021/Jo00037A046 |
0.556 |
|
| 1992 |
Maynard DF, Norman AW, Okamura WH. 18-Substituted derivatives of vitamin D: 18-Acetoxy-1α,25-dihydroxyvitamin D3 and related analogues Journal of Organic Chemistry. 57: 3214-3217. |
0.472 |
|
| 1992 |
Craig AS, Norman AW, Okamura WH. Two novel allenic side chain analogues of 1α,25-dihydroxyvitamin D3 Journal of Organic Chemistry. 57: 4374-4380. |
0.327 |
|
| 1991 |
Henry HL, Fried S, Shen GY, Barrack SA, Okamura WH. Effect of three A-ring analogs of 1 alpha,25-dihydroxyvitamin D3 on 25-OH-D3-1 alpha-hydroxylase in isolated mitochondria and on 25-hydroxyvitamin D3 metabolism in cultured kidney cells. The Journal of Steroid Biochemistry and Molecular Biology. 38: 775-9. PMID 2064993 DOI: 10.1016/0960-0760(91)90091-I |
0.523 |
|
| 1991 |
Figadère B, Norman AW, Henry HL, Koeffler HP, Zhou JY, Okamura WH. Arocalciferols: synthesis and biological evaluation of aromatic side-chain analogues of 1 alpha,25-dihydroxyvitamin D3(1a). Journal of Medicinal Chemistry. 34: 2452-63. PMID 1652020 DOI: 10.1021/Jm00112A021 |
0.535 |
|
| 1991 |
Zhou JY, Norman AW, Akashi M, Chen DL, Uskokovic MR, Aurrecoechea JM, Dauben WG, Okamura WH, Koeffler HP. Development of a novel 1,25(OH)2-vitamin D3 analog with potent ability to induce HL-60 cell differentiation without modulating calcium metabolism. Blood. 78: 75-82. PMID 1648977 |
0.443 |
|
| 1991 |
Park G, Okamura WH. The stereospecific tert-butyllithium reduction of triene sulfoxides: Improved levels of deuterium incorporation Synthetic Communications. 21: 1047-1054. DOI: 10.1080/00397919108019794 |
0.343 |
|
| 1991 |
Curtin ML, Okamura WH. Vitamin D (calciferol) and its analogs. 40. 1.alpha.,25-Dihydroxyprevitamin D3: synthesis of the 9,14,19,19,19-pentadeuterio derivative and a kinetic study of its [1,7]-sigmatropic shift to 1.alpha.,25-dihydroxyvitamin D3 Journal of the American Chemical Society. 113: 6958-6966. DOI: 10.1021/Ja00018A038 |
0.557 |
|
| 1991 |
Enas JD, Shen GY, Okamura WH. [1,7]-sigmatropic hydrogen shifts of A-norvitamin D analogues: Ring size and substituent effects on the previtamin D-vitamin D equilibrium Journal of the American Chemical Society. 113: 3873-3881. DOI: 10.1021/Ja00010A032 |
0.533 |
|
| 1991 |
Enas JD, Palenzuela JA, Okamura WH. Studies on vitamin D (calciferol) and its analogs. 37. A-Homo-11-hydroxy-3-deoxy vitamin D: ring size and .pi.-facial selectivity effects on the [1,7]-sigmatropic hydrogen shift of previtamin D to vitamin D Journal of the American Chemical Society. 113: 1355-1363. DOI: 10.1021/Ja00004A043 |
0.555 |
|
| 1991 |
Curtin ML, Okamura WH. 1α,25-dihydroxyprevitamin D3: Synthesis of the 9,14,19,19,19,-pentadeuterio derivative and a kinetic study of its [1,7]-sigmatropic shift to 1α,25-dihytdroxyvitamin D3 1 Journal of the American Chemical Society. 113: 6958-6966. |
0.365 |
|
| 1991 |
Enas JD, Palenzuela JA, Okamura WH. A-homo-11-hydroxy-3-deoxyvitamin D: Ring size and π-facial selectivity effects on the [1,7]-sigmatropic hydrogen shift of previtamin D to vitamin D Journal of the American Chemical Society. 113: 1355-1363. |
0.455 |
|
| 1990 |
Wu KM, Okamura WH. Studies of vitamin D (calciferol) and its analogs. 36. Hydroxyl-directing effects on [1,7]-sigmatropic hydrogen migrations The Journal of Organic Chemistry. 55: 4025-4033. DOI: 10.1021/Jo00300A015 |
0.428 |
|
| 1989 |
Okamura WH, Aurrecoechea JM, Gibbs RA, Norman AW. Studies of vitamin D (calciferol) and its analogs. 35. Synthesis and biological activity of 9,11-dehydrovitamin D3 analogs: stereoselective preparation of 6.beta.-vitamin D vinylallenes and a concise enynol synthesis for preparing the A-ring The Journal of Organic Chemistry. 54: 4072-4083. DOI: 10.1021/Jo00278A018 |
0.621 |
|
| 1989 |
Gibbs RA, Bartels K, Lee RWK, Okamura WH. An enantioselective central-axial-central chiral element transfer process leading to a concise synthesis of (+)-sterpurene: intramolecular Diels-Alder reactions of vinylallene sulfoxides Journal of the American Chemical Society. 111: 3717-3725. DOI: 10.1021/Ja00192A033 |
0.484 |
|
| 1989 |
GIBBS RA, BARTELS K, LEE RWK, OKAMURA WH. ChemInform Abstract: An Enantioselective Central-Axial-Central Chiral Element Transfer Process Leading to a Concise Synthesis of (+)-Sterpurene: Intramolecular Diels-Alder Reactions of Vinylallene Sulfoxides. Cheminform. 20. DOI: 10.1002/chin.198936079 |
0.344 |
|
| 1989 |
Okamura WH, Aurrecoechea JM, Gibbs RA, Norman AW. Synthesis and biological activity of 9,11-dehydrovitamin D3 analogues: Stereoselective preparation of 6β-vitamin D vinylallenes and a concise enynol synthesis for preparing the A-ring Journal of Organic Chemistry. 54: 4072-4083. |
0.446 |
|
| 1988 |
Barrack SA, Gibbs RA, Okamura WH. Studies of vitamin D (calciferol) and its analogs. 34. Potential inhibitors of vitamin D metabolism: an oxa analog of vitamin D The Journal of Organic Chemistry. 53: 1790-1796. DOI: 10.1021/Jo00243A035 |
0.621 |
|
| 1988 |
Gibbs RA, Okamura WH. A short enantioselective synthesis of (+)-sterpurene: complete intramolecular transfer of central to axial to central chiral elements Journal of the American Chemical Society. 110: 4062-4063. DOI: 10.1021/Ja00220A069 |
0.425 |
|
| 1988 |
Okamura WH, Hoeger CA, Miller KJ, Reischl W. A study of the [1,7]-sigmatropic shift of a 1-hydroxylated 3-desoxy previtamin D to vitamin D: Observation of a modest primary deuterium kinetic isotope effect Journal of the American Chemical Society. 110: 973-974. DOI: 10.1021/Ja00211A051 |
0.507 |
|
| 1988 |
BARRACK SA, GIBBS RA, OKAMURA WH. ChemInform Abstract: Studies of Vitamin D (Calciferol) and Its Analogues. Part 34. Potential Inhibitors of Vitamin D Metabolism: An Oxa Analogue of Vitamin D. Cheminform. 19. DOI: 10.1002/chin.198840285 |
0.58 |
|
| 1988 |
GIBBS RA, OKAMURA WH. ChemInform Abstract: A Short Enantioselective Synthesis of (+)-Sterpurene: Complete Intramolecular Transfer of Central to Axial to Central Chiral Elements. Cheminform. 19. DOI: 10.1002/chin.198839272 |
0.335 |
|
| 1988 |
OKAMURA WH, HOEGER CA, MILLER KJ, REISCHL W. ChemInform Abstract: Vitamin D (Calciferol) and Its Analogues. Part 33. (1,7)-Sigmatropic Shift of a 1-Hydroxylated 3-Desoxy Previtamin D to Vitamin D: Observation of a Modest Primary Deuterium Kinetic Isotope Effect. Cheminform. 19. DOI: 10.1002/chin.198822321 |
0.475 |
|
| 1988 |
GIBBS RA, OKAMURA WH. ChemInform Abstract: Synthesis of 3-Deoxy-1α,25-dihydroxy-9,11-dehydrovitamin D3 (II). Selective Formation of 6β-Vitamin D Vinylallenes and Their Thermal (1,5)-Sigmatropic Hydrogen Shift. Cheminform. 19. DOI: 10.1002/chin.198820292 |
0.545 |
|
| 1988 |
Barrack SA, Gibbs RA, Okamura WH. Potential inhibitors of vitamin D metabolism: An oxa analogue of vitamin D Journal of Organic Chemistry. 53: 1790-1796. |
0.44 |
|
| 1987 |
Hoeger CA, Johnston AD, Okamura WH. Studies of vitamin D (calciferol) and its analogs. 30. Thermal [1,7]-sigmatropic hydrogen shifts: stereochemistry, kinetics, isotope effects and .pi.-facial selectivity Journal of the American Chemical Society. 109: 4690-4698. DOI: 10.1021/Ja00249A035 |
0.476 |
|
| 1987 |
Theobald PG, Okamura WH. On the stereospecific reduction of vinylsulfoxides with thepossibility of deuterium labeling Tetrahedron Letters. 28: 6565-6568. DOI: 10.1016/S0040-4039(00)96914-4 |
0.338 |
|
| 1987 |
Gibbs RA, Okamura WH. Synthesis of 3-deoxy-1α,25-dihydroxy-9,11-dehydrovitamin D3: Selective formation of 6β-vitamin D vinylallenes and their thermal [1,5]-sigmatropic hydrogen shift Tetrahedron Letters. 28: 6021-6024. DOI: 10.1016/S0040-4039(00)96853-9 |
0.613 |
|
| 1987 |
Aurrecoechea JM, Okamura WH. A short, enantiospecific synthesis of the 1α-hydroxyvitamin D enyne A-ring synthon Tetrahedron Letters. 28: 4947-4950. DOI: 10.1016/S0040-4039(00)96666-8 |
0.481 |
|
| 1987 |
HOEGER CA, JOHNSTON AD, OKAMURA WH. ChemInform Abstract: Vitamin D (Calciferol) and Its Analogues. Part 30. Thermal (1,7) Sigmatropic Hydrogen Shifts: Stereochemistry, Kinetics, Isotope Effects, and π-Facial Selectivity. Cheminform. 18. DOI: 10.1002/chin.198747358 |
0.384 |
|
| 1986 |
Barrack SA, Okamura WH. Studies on vitamin D (calciferol) and its analogs. 29. Mechanistic studies by deuterium labeling and related kinetic investigations of the [1,5]-sigmatropic hydrogen shift of vitamin D type vinylallenes The Journal of Organic Chemistry. 51: 3201-3206. DOI: 10.1021/Jo00366A025 |
0.501 |
|
| 1986 |
OKAMURA WH, HOEGER CA, JOHNSTON AD, MOURINO A. ChemInform Abstract: Recent Advances in Vitamin D Chemistry: (1,7)-Sigmatropic Hydrogen Shifts and tert-Butyl Substituted Vitamin D Analogs Chemischer Informationsdienst. 17. DOI: 10.1002/Chin.198652349 |
0.547 |
|
| 1986 |
Barrack SA, Okamura WH. Mechanistic studies by deuterium labeling and related kinetic investigations of the [1,5]-sigmatropic hydrogen shift of vitamin D type vinylallenes Journal of Organic Chemistry. 51: 3201-3206. |
0.371 |
|
| 1985 |
Haces A, van Kruchten EM, Okamura WH. On the Stereochemistry of Organocopper Mediated Conversion of Propargylic Esters to Allenes Israel Journal of Chemistry. 26: 140-146. DOI: 10.1002/Ijch.198500084 |
0.38 |
|
| 1985 |
Chauhan YS, Chandraratna RAS, Miller DA, Kondrat RW, Reischl W, Okamura WH. On a tandem 1,2-elimination/[1,7]-sigmatropic shift: Synthesis of double bond shifted isomers of vitamin A Journal of the American Chemical Society. 107: 1028-1033. DOI: 10.1002/Chin.198527362 |
0.406 |
|
| 1984 |
Jeganathan S, Johnston AD, Kuenzel EA, Norman AW, Okamura WH. Thermal rearrangement of vinylallenes: synthesis of 3-deoxy-1.alpha.-hydroxy-14-epiprevitamin D3 The Journal of Organic Chemistry. 49: 2152-2158. DOI: 10.1021/Jo00186A015 |
0.486 |
|
| 1984 |
Chandraratna RAS, Okamura WH. 12-S-CIS conformationally locked retinoids: Thermal and photochemical interconversions leading to new geometric isomers Tetrahedron Letters. 25: 1003-1006. DOI: 10.1016/S0040-4039(01)80085-X |
0.343 |
|
| 1984 |
Jeganathan S, Johnston AD, Kuenzel EA, Norman AW, Okamura WH. Thermal rearrangement of vinylallenes: Synthesis of 3-deoxy-1α-hydroxy-14-epiprevitamin D3 Journal of Organic Chemistry. 49: 2152-2158. DOI: 10.1002/Chin.198447362 |
0.459 |
|
| 1983 |
Mayer E, Reddy GS, Chandraratna RA, Okamura WH, Kruse JR, Popjàk G, Bishop JE, Norman AW. 23,25-Dihydroxy-24-oxovitamin D3: a metabolite of vitamin D3 made in the kidney. Biochemistry. 22: 1798-805. PMID 6849888 DOI: 10.1021/Bi00277A009 |
0.439 |
|
| 1983 |
Mayer E, Bishop JE, Chandraratna RA, Okamura WH, Kruse JR, Popjak G, Ohnuma N, Norman AW. Isolation and identification of 1,25-dihydroxy-24-oxo-vitamin D3 and 1,23,25-trihydroxy-24-oxo-vitamin D3. New metabolites of vitamin D3 produced by a C-24 oxidation pathway of metabolism for 1,25-dihydroxyvitamin D3 present in intestine and kidney. The Journal of Biological Chemistry. 258: 13458-65. PMID 6315697 |
0.441 |
|
| 1983 |
Toh HT, Okamura WH. Studies on vitamin D (calciferol) and its analogs. 25. Studies on a convergent route to side-chain analogues of vitamin D: 25-hydroxy-23-oxavitamin D3 The Journal of Organic Chemistry. 48: 1414-1417. DOI: 10.1021/Jo00157A004 |
0.557 |
|
| 1983 |
Chandraratna RAS, Bayerque AL, Okamura WH. 12-s-cis conformationally locked 11-cis-retinoids: A delineation of the thermal requirements for [1,5]-sigmatropic shifts and electrocyclizations in the vitamin A series and novel spectral properties Journal of the American Chemical Society. 105: 3588-3594. DOI: 10.1021/Ja00349A039 |
0.362 |
|
| 1983 |
van Kruchten EMGA, Haces A, Okamura WH. Configurational stability of allenic anions, use of a vitamin D derived CD fragment as a stereochemical probe and the stereoselective synthesis of precursors Tetrahedron Letters. 24: 3939-3942. DOI: 10.1016/S0040-4039(00)88230-1 |
0.442 |
|
| 1983 |
Gerdes JM, Okamura WH. Studies on vitamin D (calciferol) and its analogs. Part 26. Effect of seven-membered ring fusion on thermal pericyclic processes of vinylallenes and other seco steroids related to A-homovitamin D The Journal of Organic Chemistry. 48: 4030-4035. DOI: 10.1002/Chin.198414100 |
0.539 |
|
| 1983 |
TOH HT, OKAMURA WH. ChemInform Abstract: STUDIES ON VITAMIN D (CALCIFEROL) AND ITS ANALOGS. 25. STUDIES ON A CONVERGENT ROUTE TO SIDE-CHAIN ANALOGUES OF VITAMIN D: 25-HYDROXY-23-OXAVITAMIN D3 Chemischer Informationsdienst. 14. DOI: 10.1002/chin.198344320 |
0.479 |
|
| 1983 |
Chandraratna RAS, Bayerque AL, Okamura WH. The 12‐S‐Cis Conformationally Locked 11‐Cis‐Retinoids: A Delineation Of The Thermal Requirements For (1,5)‐Sigmatropic Shifts And Electrocyclizations In The Vitamin A Series And Novel Spectral Properties Cheminform. 14. DOI: 10.1002/Chin.198336113 |
0.378 |
|
| 1983 |
HACES A, OKAMURA WH. ChemInform Abstract: STUDIES ON VITAMIN D (CALCIFEROL) AND ITS ANALOGS. 24. HETEROCALCIFEROLS: NOVEL 3-THIA AND 3-SULFINYL ANALOGS OF 1α-HYDROXYVITAMIN D3 Chemischer Informationsdienst. 14. DOI: 10.1002/chin.198305343 |
0.47 |
|
| 1983 |
LEYES GA, OKAMURA WH. ChemInform Abstract: STUDIES ON VITAMIN D (CALCIFEROL) AND ITS ANALOGS. 23. EFFECT OF 3-METHYL SUBSTITUENTS ON THE THERMAL (1,5)- AND (1,7)-SIGMATROPIC HYDROGEN SHIFTS OF VINYLALLENES AND OTHER SECO STEROIDS RELATED TO VITAMIN D: SYNTHESIS OF 3-METHYL- AN Chemischer Informationsdienst. 14. DOI: 10.1002/chin.198305342 |
0.449 |
|
| 1983 |
Gerdes JM, Okamura WH. Effect of seven-membered ring fusion on thermal pericyclic processes of vinylallenes and other seco steroids related to A -homovitamin D Journal of Organic Chemistry. 48: 4030-4035. |
0.315 |
|
| 1983 |
Toh HT, Okamura WH. Studies on a convergent route to side-chain analogues of vitamin D: 25-Hydroxy-23-oxavitamin D3 Journal of Organic Chemistry. 48: 1414-1417. |
0.463 |
|
| 1982 |
Chandraratna RAS, Okamura WH. 12-s-Cis-locked retinoids (vitamin A): Synthesis and novel spectral properties Journal of the American Chemical Society. 104: 6114-6115. DOI: 10.1021/Ja00386A046 |
0.407 |
|
| 1982 |
Haces A, Okamura WH. Studies on vitamin D (calciferol) and its analogs. 24. Heterocalciferols: novel 3-thia and 3-sulfinyl analogs of 1.alpha.-hydroxyvitamin D3 Journal of the American Chemical Society. 104: 6105-6109. DOI: 10.1021/Ja00386A043 |
0.568 |
|
| 1982 |
Leyes GA, Okamura WH. Studies on vitamin D (calciferol) and its analogs. 23. Effect of 3-methyl substituents on the thermal [1,5]- and [1,7]-sigmatropic hydrogen shifts of vinylallenes and other seco steroids related to vitamin D: synthesis of 3-methyl- and 3,3-dimethyl-substituted analogs of 3-deoxy-1.alpha.,25-dihydroxyvitamin D3 Journal of the American Chemical Society. 104: 6099-6105. DOI: 10.1021/Ja00386A042 |
0.576 |
|
| 1982 |
Haces A, van Kruchten EMGA, Okamura WH. On the lithium dimethylcuprate induced conversion of propargylic esters into allenes using a steroidal C/D fragment derived from vitamin D3 as a stereochemical probe. Tetrahedron Letters. 23: 2707-2710. DOI: 10.1016/S0040-4039(00)87437-7 |
0.532 |
|
| 1982 |
van Kruchten EMGA, Okamura WH. On the [2,3]-sigmatropic rearrangements of sulfenate esters derived from alkenynols: synthesis of vinylallene and vinylacetylene sulfoxides. Tetrahedron Letters. 23: 1019-1022. DOI: 10.1016/S0040-4039(00)87011-2 |
0.309 |
|
| 1982 |
Jeganathan S, Okamura WH. 2,3-Di(phenylsulfinyl)-1,3-butadiene via a double [2,3]-sigmatropic rearrangement of the bis-sulfenate ester of 2-butyne-1,4-diol. Tetrahedron Letters. 23: 4763-4764. DOI: 10.1016/S0040-4039(00)85707-X |
0.308 |
|
| 1982 |
Haces A, Okamura WH. Heterocalciferols: Novel 3-thia and 3-sulfinyl analogues of 1α-hydroxyvitamin D3 Journal of the American Chemical Society. 104: 6105-6109. |
0.367 |
|
| 1982 |
Leyes GA, Okamura WH. Effect of 3-methyl substituents on the thermal [1,5]- and [1,7]-stigmatropic hydrogen shifts of vinylallenes and other seco steroids related to vitamin D: Synthesis of 3-methyl-and 3,3-dimethyl-substituted analogues of 3-deoxy-1α,25-dihydroxyvitamin D3 Journal of the American Chemical Society. 104: 6099-6105. |
0.434 |
|
| 1981 |
Mayer E, Kadowaki S, Okamura WH, Ohnuma N, Leyes GA, Schmidt-Gayk H, Norman AW. Studies on the mode of action of calciferol-XXXV. Comparison of the biochemical properties and ligand specificities of receptors and antibodies for 1,25-dihydroxyvitamin D3. Journal of Steroid Biochemistry. 15: 145-51. PMID 6279964 DOI: 10.1016/0022-4731(81)90269-7 |
0.488 |
|
| 1981 |
Gerdes JM, Okamura WH, Norman AW. Biochemical properties of A-homovitamin D derivatives: 1,4-dihydroxy-3-deoxy-A-homo-19-nor-9, 10-secocholesta-5,7-dienes. Archives of Biochemistry and Biophysics. 210: 238-45. PMID 6271069 DOI: 10.1016/0003-9861(81)90185-5 |
0.526 |
|
| 1981 |
Gerdes JM, Lewicka-Piekut S, Condran P, Okamura WH. Studies on vitamin D (calciferol and its analogs). 22. Synthesis and thermolysis of A-norvinylallenes related to vitamin D The Journal of Organic Chemistry. 46: 5197-5200. DOI: 10.1021/Jo00338A027 |
0.557 |
|
| 1981 |
Gerdes JM, Norman AW, Okamura WH. Studies on vitamin D (calciferol) and its analogues. 21. Solvolytic ring expansions of vitamin D3. Formation of 1,4-dihydroxy-A-homo-19-nor-9,10-secocholesta-5,7-diene Journal of Organic Chemistry. 46: 599-602. DOI: 10.1021/Jo00316A022 |
0.558 |
|
| 1981 |
Mourino A, Lewicka-Piekut S, Norman AW, Okamura WH. Vitamin D (Calciferol) And Its Analogs. 20. Synthesis Of 3-Deoxy-3,3-Dimethyl-1-Hydroxyvitamin D3 From Vinylallene Intermediates And Related Thermal And Configurational Studies Cheminform. 12. DOI: 10.1002/Chin.198104338 |
0.567 |
|
| 1981 |
Condran PJ, Okamura WH. Vitamin D (calciferol) and its analogs. 19. Rearrangement of vinylallenes to 1-hydroxylated vitamin D model systems lacking the D ring and side chain Cheminform. 12. DOI: 10.1002/Chin.198104337 |
0.55 |
|
| 1981 |
Gerdes JM, Lewicka-Piekut S, Condran P, Okamura WH. Synthesis and thermolysis of A-norvinylallenes related to vitamin D Journal of Organic Chemistry. 46: 5197-5200. |
0.466 |
|
| 1980 |
Mourino A, Lewicka-Piekut S, Norman AW, Okamura WH. Vitamin D (calciferol) and its analogs. 20. Synthesis of 3-deoxy-3,3-dimethyl-1-hydroxyvitamin D3 from vinylallene intermediates and related thermal and configurational studies The Journal of Organic Chemistry. 45: 4015-4020. DOI: 10.1021/Jo01308A014 |
0.567 |
|
| 1980 |
Condran P, Okamura WH. Vitamin D (calciferol) and its analogs. 19. Rearrangement of vinylallenes to 1-hydroxylated vitamin D model systems lacking the D ring and side chain Journal of Organic Chemistry. 45: 4011-4015. DOI: 10.1021/Jo01308A013 |
0.55 |
|
| 1980 |
Condran P, Hammond ML, Mouriño A, Okamura WH. Studies on vitamin D (calciferol) and its analogues. 18. The vinylallene approach to the 1-hydroxyvitamin D system. New sigmatropic reactions in the vitamin D series Journal of the American Chemical Society. 102: 6259-6267. DOI: 10.1021/Ja00540A014 |
0.554 |
|
| 1980 |
Mouriño A, Lewicka-Piekut S, Norman AW, Okamura WH. Studies on vitamin D (calciferol) and its analogues. 20. Synthesis of 3-deoxy-3,3-dimethyl-1-hydroxy vitamin D3 from vinylallene intermediates and related thermal and configurational studies Journal of Organic Chemistry. 45: 4015-4020. |
0.487 |
|
| 1980 |
Condran P, Okamura WH. Studies on vitamin D (calciferol) and its analogues. 19. Rearrangement of vinylallenes to 1-hydroxylated vitamin D model systems lacking the D ring and side chain Journal of Organic Chemistry. 45: 4011-4015. |
0.468 |
|
| 1979 |
Norman AW, Johnson RL, Okamura WH. 24-Nor-25-hydroxyvitamin D3. A specific antagonist of vitamin D3 action in the chick. The Journal of Biological Chemistry. 254: 11450-6. PMID 500652 |
0.459 |
|
| 1979 |
MOURINO A, BLAIR P, WECKSLER W, JOHNSON RL, NORMAN AW, OKAMURA WH. ChemInform Abstract: STUDIES ON VITAMIN D (CALCIFEROL) AND ITS ANALOGS. 15. 24-NOR-1α,25-DIHYDROXYVITAMIN D3 AND 24-NOR-25-HYDROXY-5,6-TRANS-VITAMIN D3 Chemischer Informationsdienst. 10. DOI: 10.1002/Chin.197908323 |
0.564 |
|
| 1979 |
MESSING AW, ROSS FP, NORMAN AW, OKAMURA WH. ChemInform Abstract: STUDIES ON VITAMIN D (CALCIFEROL) AND ITS ANALOGS. 17. HYDROZIRCONATION-PROTONATION OF VITAMIN D Chemischer Informationsdienst. 10. DOI: 10.1002/Chin.197903316 |
0.548 |
|
| 1978 |
Wecksler WR, Okamura WH, Norman AW. Studies on the mode of action of vitamin D--XIV. Quantitative assessment of the structural requirements for the interaction of 1 alpha, 25-dihydroxyvitamin D3 with its chick intestinal mucosa receptor system. Journal of Steroid Biochemistry. 9: 929-37. PMID 745395 DOI: 10.1016/0022-4731(78)90053-5 |
0.453 |
|
| 1978 |
Okamura WH, Mitra MN, Pirio MR, Mouriño A, Carey SC, Norman AW. Studies on vitamin D (calciferol) and its analogues. 13. 3-Deoxy-3alpha-methyl-1alpha-hydroxyvitamin D3, 3-deoxy-3alpha-methyl-1alpha,25-dihydroxyvitamin D3, and 1alpha-hydroxy-3-epivitamin D3. Analogues with conformationally biased a rings. The Journal of Organic Chemistry. 43: 574-80. PMID 632961 DOI: 10.1021/Jo00398A011 |
0.481 |
|
| 1978 |
Mouriño A, Blair P, Wecksler W, Johnson RL, Norman AW, Okamura WH. Studies on vitamin D (calciferol) and its analogues. 15. 24-Nor-1alpha,25-dihydroxyvitamin D3 and 24-nor-25-hydroxy-5,6-trans-vitamin D3. Journal of Medicinal Chemistry. 21: 1025-9. PMID 214553 DOI: 10.1021/Jm00208A005 |
0.579 |
|
| 1978 |
Mouriño A, Okamura WH. Studies on vitamin D (calciferol) and its analogues. 14. On the 10,19-dihydrovitamins related to vitamin D2 including dihydrotachysterol2 Journal of Organic Chemistry. 43: 1653-1656. DOI: 10.1021/Jo00403A006 |
0.546 |
|
| 1978 |
Hammond ML, Mourino A, Okamura WH. Sigmatropic rearrangement of vinylallenes: a novel route to the 1-hydroxyvitamin D system Journal of the American Chemical Society. 100: 4907-4908. DOI: 10.1021/Ja00483A054 |
0.517 |
|
| 1978 |
Messing AW, Ross FP, Norman AW, Okamura WH. Hydrozirconation-protonation of vitamin D Tetrahedron Letters. 19: 3635-3636. DOI: 10.1016/S0040-4039(01)95016-6 |
0.534 |
|
| 1978 |
Hammond ML, Mourino A, Okamura WH. Sigmatropic rearrangement of vinylallenes: a novel route to the 1-hydroxyvitamin D system Cheminform. 9. DOI: 10.1002/Chin.197845346 |
0.517 |
|
| 1978 |
OKAMURA WH, MITRA MN, PIRIO MR, MOURINO A, CAREY SC, NORMAN AW. ChemInform Abstract: STUDIES ON VITAMIN D (CALCIFEROL) AND ITS ANALOGS. 13. 3-DEOXY-3α-METHYL-1α-HYDROXYVITAMIN D3, 3-DEOXY-3α-METHYL-1α,25-DIHYDROXYVITAMIN D3, AND 1α-HYDROXY-3-EPIVITAMIN D3. ANALOGS WITH CONFORMATIONALLY BIASED A RINGS Chemischer Informationsdienst. 9. DOI: 10.1002/Chin.197828324 |
0.469 |
|
| 1978 |
Hammond ML, Mouriño A, Okamura WH. Sigmatropic rearrangement of vinylallenes: A novel route to the 1-hydroxyvitamin D system [15] Journal of the American Chemical Society. 100: 4907-4908. |
0.427 |
|
| 1977 |
Johnson RL, Carey SC, Norman AW, Okamura WH. Studies on vitamin D (calciferol) and its analogues. 10. Side-chain analogues of 25-hydroxyvitamin D3. Journal of Medicinal Chemistry. 20: 5-11. PMID 833826 DOI: 10.1021/Jm00211A002 |
0.54 |
|
| 1977 |
Okamura WH, Hammond ML, Rego A, Norman AW, Wing RM. Studies on vitamin D (calciferol) and its analogues. 12. Structural and synthetic studies of 5,6-trans-vitamin D3 and the stereoisomers of 10,19-dihydrovitamin D3 including dihydrotachysterol3. The Journal of Organic Chemistry. 42: 2284-91. PMID 195026 DOI: 10.1002/Chin.197742389 |
0.559 |
|
| 1977 |
Norman AW, Okamura WH. Conformational analysis of calciferol steroids and study of their interaction with the vitamin D endocrine system | PROC. V. INT. CONGR. ENDOCRINOLOGY VOL. I Excerpta Medica,Amsterdam,Ics. 561-564. |
0.383 |
|
| 1977 |
Norman AW, Hammond ML, Okamura WH. 19-Hydroxy-10S(19)-dihydrovitamin D3-II An analogue of vitamin D3 which possesses 'anti-vitamin' activity Federation Proceedings. 36: No.3396. |
0.439 |
|
| 1976 |
Brickman AS, Coburn JW, Friedman GR, Okamura WH, Massry SG, Norman AW. Comparison of effects of 1 alpha-hydroxy-vitamin D3 and 1,25-dihydroxy-vitamin D3 in man. The Journal of Clinical Investigation. 57: 1540-7. PMID 932193 DOI: 10.1172/Jci108424 |
0.517 |
|
| 1976 |
Norman AW, Johnson RL, Osborn TW, Procsal DA, Carey SC, Hammond ML, Mitra MN, Pirio MR, Rego A, Wing RM, Okamura WH. The chemistry and conformational and biological analysis of vitamin D3, its metabolites and analogues. Clinical Endocrinology. 5: 121S-143S. PMID 212225 DOI: 10.1111/J.1365-2265.1976.Tb03821.X |
0.534 |
|
| 1976 |
Procsal DA, Okamura WH, Norman AW. Vitamin D, its metabolites and analogs: a review of the structural requirements for biological activity. The American Journal of Clinical Nutrition. 29: 1271-82. PMID 187054 DOI: 10.1093/Ajcn/29.11.1271 |
0.379 |
|
| 1976 |
Norman AW, Okamura WH, Friedlander EJ, Henry HL, Johnson RL, Mitra MN, Proscal DA, Wecksler WW. Current concepts of the chemical conformation, metabolism, and interaction of the steroid, vitamin D, with the endocrine system for calcium homeostasis. Calcified Tissue Research. 21: 153-9. PMID 182332 DOI: 10.1007/BF02546444 |
0.313 |
|
| 1976 |
Okamura WH, Hammond ML, Jacobs HJC, Thuijl Jv. The mass spectra of suprasterol3-II, vitamin D3 and related molecules Tetrahedron Letters. 17: 4807-4810. DOI: 10.1016/S0040-4039(00)78915-5 |
0.441 |
|
| 1976 |
OKAMURA WH, PIRIO MR. ChemInform Abstract: VITAMIN D (CALCIFEROL) AND ITS ANALOGS. IX. 1α-HYDROXY-3-EPIVITAMIN D3, , ITS SYNTHESIS AND CONFORMATIONAL ANALYSIS Chemischer Informationsdienst. 7: no-no. DOI: 10.1002/chin.197609354 |
0.481 |
|
| 1976 |
Okamura WH, Hammond ML, Rego A. A ring and side chain vitamin D analogues: synthesis and conformational analysis Israel Journal of Medical Sciences. 12: 1487-1488. |
0.422 |
|
| 1975 |
Norman AW, Mitra MN, Okamura WH, Wing RM. Vitamin D: 3-deoxy-lalpha-hydroxyvitamin D3, biologically active analog of lalpha-dihydroxyvitamin D3. Science (New York, N.Y.). 188: 1013-5. PMID 1145184 DOI: 10.1126/Science.1145184 |
0.55 |
|
| 1975 |
Johnson RL, Okamura WH, Norman AW. Studies on the mode of action of calciferol. X. 24-Nor-25-hydroxyvitamin D3, an analog of 25-hydroxyvitamin D3 having "anti-vitamin" activity. Biochemical and Biophysical Research Communications. 67: 797-802. PMID 173329 DOI: 10.1016/0006-291X(75)90883-9 |
0.538 |
|
| 1975 |
Procsal DA, Okamura WH, Norman AW. Structural requirements for the interaction of 1 alpha, 25-(OH) 2- vitiamin D3 with its chick interestinal receptor system. The Journal of Biological Chemistry. 250: 8382-8. PMID 172496 |
0.372 |
|
| 1975 |
Norman AW, Procsal DA, Okamura WH, Wing RM. Structure-function studies of the interaction of the hormonally active form of vitamin D3, 1alpha, 25-dihydroxy-vitamin D3, with the intestine. Journal of Steroid Biochemistry. 6: 461-7. PMID 171496 DOI: 10.1016/0022-4731(75)90173-9 |
0.554 |
|
| 1975 |
Wing RM, Okamura WH, Rego A, Pirio MR, Norman AW. Studies on vitamin D and its analogs. VIII. Solution conformations of vitamin D3 and 1 alpha, 25-dihydroxyvitamin D3 by high-resolution proton magnetic resonance spectroscopy. Journal of the American Chemical Society. 97: 4980-5. PMID 170323 DOI: 10.1021/Ja00850A036 |
0.537 |
|
| 1975 |
Okamura WH, Mitra MN, Procsal DA, Norman AW. Studies on vitamin D and its analogs. VIII. 3-Deoxy-1alpha, 25-dihydroxyvitamin D3, a potent new analog of 1alpha, 25-(OH) 2-D3. Biochemical and Biophysical Research Communications. 65: 24-30. PMID 167766 DOI: 10.1016/S0006-291X(75)80056-8 |
0.557 |
|
| 1975 |
Okamura WH, Pirio MR. Studies on vitamin d (calciferol) and its analogs. IX. lα-hydroxy-3-epivitamin D3: Its synthesis and conformational analysis. Tetrahedron Letters. 16: 4317-4320. DOI: 10.1016/S0040-4039(00)91112-2 |
0.573 |
|
| 1975 |
WING RM, OKAMURA WH, REGO A, PIRIO MR, NORMAN AW. ChemInform Abstract: STUDIES ON VITAMIN D AND ITS ANALOGS PART 7, SOLUTION CONFORMATIONS OF VITAMIN D3 AND 1ALPHA,25-DIHYDROXYVITAMIN D3 BY HIGH-RESOLUTION PROTON MAGNETIC RESONANCE SPECTROSCOPY Chemischer Informationsdienst. 6: no-no. DOI: 10.1002/Chin.197544066 |
0.539 |
|
| 1974 |
Wing RM, Okamura WH, Pirio MR, Sine SM, Norman AW. Vitamin D in solution: conformations of vitamin D3, 1alpha,25-dihydroxyvitamin D3, and dihydrotachysterol3. Science (New York, N.Y.). 186: 939-41. PMID 4377759 DOI: 10.1126/Science.186.4167.939 |
0.564 |
|
| 1974 |
Sine SM, Conklin TE, Okamura WH. Studies on vitamin D and its analogs. VI. 3-deoxy-A-homovitamin D3, a model synthesis. The Journal of Organic Chemistry. 39: 3797-9. PMID 4377157 DOI: 10.1021/Jo00939A048 |
0.558 |
|
| 1974 |
Okamura WH, Norman AW, Wing RM. Vitamin D: concerning the relationship between molecular topology and biological function. Proceedings of the National Academy of Sciences of the United States of America. 71: 4194-7. PMID 4372612 DOI: 10.1073/Pnas.71.10.4194 |
0.54 |
|
| 1974 |
Okamura WH, Mitra MN, Wing RM, Norman AW. Chemical synthesis and biological activity of 3-deoxy-1alpha-hydroxyvitamin D3 an analog of 1alpha,25-(OH)2-D3, the active form of vitamin D3. Biochemical and Biophysical Research Communications. 60: 179-85. PMID 4371082 DOI: 10.1016/0006-291X(74)90189-2 |
0.556 |
|
| 1974 |
Mitra MN, Norman AW, Okamura WH. Studies on vitamin D and its analogs. I. Synthesis of 1alpha-hydroxycholest-5-ene. The Journal of Organic Chemistry. 39: 2931-3. PMID 4370407 DOI: 10.1021/Jo00933A027 |
0.551 |
|
| 1974 |
MITRA MN, NORMAN AW, OKAMURA WH. ChemInform Abstract: STUDIES ON VITAMIN D AND ITS ANALOGS PART 1, SYNTHESIS OF 1ALPHA-HYDROXYCHOLEST-5-ENE Chemischer Informationsdienst. 5: no-no. DOI: 10.1002/Chin.197452450 |
0.555 |
|
| 1974 |
Mitra MN, Norman AW, Okamura WH. Studies on vitamin D and its analogs. I. Synthesis of 1α-hydroxycholest-5-ene Journal of Organic Chemistry. 39: 2931-2933. |
0.448 |
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| 1967 |
Okamura WH, Sondheimer F. 1,3,7,9,13,15-Hexadehydro[18]annulene Journal of the American Chemical Society. 89: 5991-5992. DOI: 10.1021/Ja00999A070 |
0.454 |
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| 1967 |
Okamura WH, Sondheimer F. 1,3,7,9,13,15-Hexadehydro[18]annulene [34] Journal of the American Chemical Society. 89: 5991-5992. |
0.392 |
|
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