E. Helene Sage - Publications

Affiliations: 
2006 Hope Heart Matrix Biology Program Benaroya Research Institute 
Area:
Molecular Biology

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Year Citation  Score
2014 Murphy-Ullrich JE, Sage EH. Revisiting the matricellular concept. Matrix Biology : Journal of the International Society For Matrix Biology. 37: 1-14. PMID 25064829 DOI: 10.1016/J.Matbio.2014.07.005  0.375
2013 Oh DJ, Kang MH, Ooi YH, Choi KR, Sage EH, Rhee DJ. Overexpression of SPARC in human trabecular meshwork increases intraocular pressure and alters extracellular matrix. Investigative Ophthalmology & Visual Science. 54: 3309-19. PMID 23599341 DOI: 10.1167/Iovs.12-11362  0.365
2013 Cheng L, Sage EH, Yan Q. SPARC fusion protein induces cellular adhesive signaling. Plos One. 8: e53202. PMID 23349702 DOI: 10.1371/Journal.Pone.0053202  0.475
2012 Rangel R, Guzman-Rojas L, le Roux LG, Staquicini FI, Hosoya H, Barbu EM, Ozawa MG, Nie J, Jr KD, Langley RR, Sage EH, Koivunen E, Gelovani JG, Lobb RR, Sidman RL, et al. Combinatorial targeting and discovery of ligand-receptors in organelles of mammalian cells. Nature Communications. 3: 788. PMID 22510693 DOI: 10.1038/Ncomms1773  0.307
2012 Millecamps M, Tajerian M, Naso L, Sage EH, Stone LS. Lumbar intervertebral disc degeneration associated with axial and radiating low back pain in ageing SPARC-null mice. Pain. 153: 1167-79. PMID 22414871 DOI: 10.1016/J.Pain.2012.01.027  0.32
2011 Kucukdereli H, Allen NJ, Lee AT, Feng A, Ozlu MI, Conatser LM, Chakraborty C, Workman G, Weaver M, Sage EH, Barres BA, Eroglu C. Control of excitatory CNS synaptogenesis by astrocyte-secreted proteins Hevin and SPARC. Proceedings of the National Academy of Sciences of the United States of America. 108: E440-9. PMID 21788491 DOI: 10.1073/Pnas.1104977108  0.318
2011 Weaver M, Workman G, Schultz CR, Lemke N, Rempel SA, Sage EH. Proteolysis of the matricellular protein hevin by matrix metalloproteinase-3 produces a SPARC-like fragment (SLF) associated with neovasculature in a murine glioma model. Journal of Cellular Biochemistry. 112: 3093-102. PMID 21688302 DOI: 10.1002/Jcb.23235  0.36
2011 Workman G, Sage EH. Identification of a sequence in the matricellular protein SPARC that interacts with the scavenger receptor stabilin-1. Journal of Cellular Biochemistry. 112: 1003-8. PMID 21308731 DOI: 10.1002/Jcb.23015  0.382
2011 Nie J, Bradshaw AD, Delany AM, Sage EH. Inactivation of SPARC enhances high-fat diet-induced obesity in mice. Connective Tissue Research. 52: 99-108. PMID 20615096 DOI: 10.3109/03008207.2010.483747  0.64
2010 Bota PC, Collie AM, Puolakkainen P, Vernon RB, Sage EH, Ratner BD, Stayton PS. Biomaterial topography alters healing in vivo and monocyte/macrophage activation in vitro. Journal of Biomedical Materials Research. Part A. 95: 649-57. PMID 20725970 DOI: 10.1002/Jbm.A.32893  0.335
2010 Seet LF, Su R, Barathi VA, Lee WS, Poh R, Heng YM, Manser E, Vithana EN, Aung T, Weaver M, Sage EH, Wong TT. SPARC deficiency results in improved surgical survival in a novel mouse model of glaucoma filtration surgery. Plos One. 5: e9415. PMID 20195533 DOI: 10.1371/Journal.Pone.0009415  0.371
2010 Weaver MS, Workman G, Cardo-Vila M, Arap W, Pasqualini R, Sage EH. Processing of the matricellular protein hevin in mouse brain is dependent on ADAMTS4. The Journal of Biological Chemistry. 285: 5868-77. PMID 20018883 DOI: 10.1074/Jbc.M109.070318  0.336
2010 Arnold SA, Rivera LB, Miller AF, Carbon JG, Dineen SP, Xie Y, Castrillon DH, Sage EH, Puolakkainen P, Bradshaw AD, Brekken RA. Lack of host SPARC enhances vascular function and tumor spread in an orthotopic murine model of pancreatic carcinoma. Disease Models & Mechanisms. 3: 57-72. PMID 20007485 DOI: 10.1242/Dmm.003228  0.619
2009 Nie J, Sage EH. SPARC functions as an inhibitor of adipogenesis. Journal of Cell Communication and Signaling. 3: 247-54. PMID 19798596 DOI: 10.1007/S12079-009-0064-4  0.454
2009 Schellings MW, van Almen GC, Sage EH, Heymans S. Thrombospondins in the heart: potential functions in cardiac remodeling. Journal of Cell Communication and Signaling. 3: 201-13. PMID 19798592 DOI: 10.1007/S12079-009-0070-6  0.322
2009 Mandelin J, Lin EC, Hu DD, Knowles SK, Do KA, Wang X, Sage EH, Smith JW, Arap W, Pasqualini R. Extracellular and intracellular mechanisms that mediate the metastatic activity of exogenous osteopontin. Cancer. 115: 1753-64. PMID 19224553 DOI: 10.1002/Cncr.24170  0.328
2009 Haddadin RI, Oh DJ, Kang MH, Filippopoulos T, Gupta M, Hart L, Sage EH, Rhee DJ. SPARC-null mice exhibit lower intraocular pressures. Investigative Ophthalmology & Visual Science. 50: 3771-7. PMID 19168904 DOI: 10.1167/Iovs.08-2489  0.337
2009 Schellings MW, Vanhoutte D, Swinnen M, Cleutjens JP, Debets J, van Leeuwen RE, d'Hooge J, Van de Werf F, Carmeliet P, Pinto YM, Sage EH, Heymans S. Absence of SPARC results in increased cardiac rupture and dysfunction after acute myocardial infarction. The Journal of Experimental Medicine. 206: 113-23. PMID 19103879 DOI: 10.1084/Jem.20081244  0.387
2009 Nie J, Sage EH. SPARC inhibits adipogenesis by its enhancement of beta-catenin signaling. The Journal of Biological Chemistry. 284: 1279-90. PMID 18990699 DOI: 10.1074/Jbc.M808285200  0.441
2008 Gruber HE, Bornstein P, Sage EH, Ingram JA, Zinchenko N, Norton HJ, Hanley EN. Disruption of the thrombospondin-2 gene alters the lamellar morphology but does not permit vascularization of the adult mouse lumbar disc. Arthritis Research & Therapy. 10: R96. PMID 18718009 DOI: 10.1186/Ar2483  0.386
2008 Nie J, Chang B, Traktuev DO, Sun J, March K, Chan L, Sage EH, Pasqualini R, Arap W, Kolonin MG. IFATS collection: Combinatorial peptides identify alpha5beta1 integrin as a receptor for the matricellular protein SPARC on adipose stromal cells. Stem Cells (Dayton, Ohio). 26: 2735-45. PMID 18583538 DOI: 10.1634/Stemcells.2008-0212  0.353
2008 Weaver MS, Workman G, Sage EH. The copper binding domain of SPARC mediates cell survival in vitro via interaction with integrin beta1 and activation of integrin-linked kinase. The Journal of Biological Chemistry. 283: 22826-37. PMID 18503049 DOI: 10.1074/Jbc.M706563200  0.362
2008 Golembieski WA, Thomas SL, Schultz CR, Yunker CK, McClung HM, Lemke N, Cazacu S, Barker T, Sage EH, Brodie C, Rempel SA. HSP27 mediates SPARC-induced changes in glioma morphology, migration, and invasion. Glia. 56: 1061-75. PMID 18442089 DOI: 10.1002/Glia.20679  0.437
2008 Sullivan MM, Puolakkainen PA, Barker TH, Funk SE, Sage EH. Altered tissue repair in hevin-null mice: inhibition of fibroblast migration by a matricellular SPARC homolog. Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society. 16: 310-9. PMID 18318815 DOI: 10.1111/J.1524-475X.2008.00370.X  0.457
2008 Kzhyshkowska J, Gratchev A, Schmuttermaier C, Brundiers H, Krusell L, Mamidi S, Zhang J, Workman G, Sage EH, Anderle C, Sedlmayr P, Goerdt S. Alternatively activated macrophages regulate extracellular levels of the hormone placental lactogen via receptor-mediated uptake and transcytosis. Journal of Immunology (Baltimore, Md. : 1950). 180: 3028-37. PMID 18292525 DOI: 10.4049/Jimmunol.180.5.3028  0.313
2008 Clark CJ, Sage EH. A prototypic matricellular protein in the tumor microenvironment--where there's SPARC, there's fire. Journal of Cellular Biochemistry. 104: 721-32. PMID 18253934 DOI: 10.1002/Jcb.21688  0.311
2007 Gotoh N, Perdue NR, Matsushima H, Sage EH, Yan Q, Clark JI. An in vitro model of posterior capsular opacity: SPARC and TGF-beta2 minimize epithelial-to-mesenchymal transition in lens epithelium. Investigative Ophthalmology & Visual Science. 48: 4679-87. PMID 17898292 DOI: 10.1167/Iovs.07-0091  0.466
2007 Liu L, Ratner BD, Sage EH, Jiang S. Endothelial cell migration on surface-density gradients of fibronectin, VEGF, or both proteins. Langmuir : the Acs Journal of Surfaces and Colloids. 23: 11168-73. PMID 17892312 DOI: 10.1021/La701435X  0.427
2007 Rentz TJ, Poobalarahi F, Bornstein P, Sage EH, Bradshaw AD. SPARC regulates processing of procollagen I and collagen fibrillogenesis in dermal fibroblasts. The Journal of Biological Chemistry. 282: 22062-71. PMID 17522057 DOI: 10.1074/Jbc.M700167200  0.688
2007 Esposito I, Kayed H, Keleg S, Giese T, Sage EH, Schirmacher P, Friess H, Kleeff J. Tumor-suppressor function of SPARC-like protein 1/Hevin in pancreatic cancer. Neoplasia (New York, N.Y.). 9: 8-17. PMID 17325739 DOI: 10.1593/Neo.06646  0.371
2007 Tian J, Paquette-Straub C, Sage EH, Funk SE, Patel V, Galileo D, McLane MA. Inhibition of melanoma cell motility by the snake venom disintegrin eristostatin. Toxicon : Official Journal of the International Society On Toxinology. 49: 899-908. PMID 17316731 DOI: 10.1016/J.Toxicon.2006.12.013  0.435
2007 Kelly KA, Allport JR, Yu AM, Sinh S, Sage EH, Gerszten RE, Weissleder R. SPARC is a VCAM-1 counter-ligand that mediates leukocyte transmigration. Journal of Leukocyte Biology. 81: 748-56. PMID 17178915 DOI: 10.1189/Jlb.1105664  0.398
2007 Wang H, Chen S, Ratner BD, Sage EH, Jiang S. Capillary differentiation of endothelial cells on microgrooved surfaces Journal of Physical Chemistry C. 111: 14602-14606. DOI: 10.1021/Jp075746Z  0.4
2006 Chavey C, Boucher J, Monthouël-Kartmann MN, Sage EH, Castan-Laurell I, Valet P, Tartare-Deckert S, Van Obberghen E. Regulation of secreted protein acidic and rich in cysteine during adipose conversion and adipose tissue hyperplasia. Obesity (Silver Spring, Md.). 14: 1890-7. PMID 17135603 DOI: 10.1038/Oby.2006.220  0.406
2006 Järveläinen H, Puolakkainen P, Pakkanen S, Brown EL, Höök M, Iozzo RV, Sage EH, Wight TN. A role for decorin in cutaneous wound healing and angiogenesis. Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society. 14: 443-52. PMID 16939572 DOI: 10.1111/J.1743-6109.2006.00150.X  0.355
2006 Sullivan MM, Barker TH, Funk SE, Karchin A, Seo NS, Höök M, Sanders J, Starcher B, Wight TN, Puolakkainen P, Sage EH. Matricellular hevin regulates decorin production and collagen assembly. The Journal of Biological Chemistry. 281: 27621-32. PMID 16844696 DOI: 10.1074/Jbc.M510507200  0.45
2006 Kzhyshkowska J, Workman G, Cardó-Vila M, Arap W, Pasqualini R, Gratchev A, Krusell L, Goerdt S, Sage EH. Novel function of alternatively activated macrophages: stabilin-1-mediated clearance of SPARC. Journal of Immunology (Baltimore, Md. : 1950). 176: 5825-32. PMID 16670288 DOI: 10.4049/Jimmunol.176.10.5825  0.425
2006 Emerson RO, Sage EH, Ghosh JG, Clark JI. Chaperone-like activity revealed in the matricellular protein SPARC. Journal of Cellular Biochemistry. 98: 701-5. PMID 16598771 DOI: 10.1002/Jcb.20867  0.38
2006 Nozaki M, Sakurai E, Raisler BJ, Baffi JZ, Witta J, Ogura Y, Brekken RA, Sage EH, Ambati BK, Ambati J. Loss of SPARC-mediated VEGFR-1 suppression after injury reveals a novel antiangiogenic activity of VEGF-A. The Journal of Clinical Investigation. 116: 422-9. PMID 16453023 DOI: 10.1172/Jci26316  0.324
2006 Hecht JT, Sage EH. Retention of the matricellular protein SPARC in the endoplasmic reticulum of chondrocytes from patients with pseudoachondroplasia. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 54: 269-74. PMID 16286662 DOI: 10.1369/Jhc.5C6834.2005  0.378
2006 Wang H, Workman G, Chen S, Barker TH, Ratner BD, Sage EH, Jiang S. Secreted protein acidic and rich in cysteine (SPARC/osteonectin/BM-40) binds to fibrinogen fragments D and E, but not to native fibrinogen. Matrix Biology : Journal of the International Society For Matrix Biology. 25: 20-6. PMID 16263253 DOI: 10.1016/J.Matbio.2005.09.004  0.354
2006 Weaver MS, Sage EH, Yan Q. Absence of SPARC in lens epithelial cells results in altered adhesion and extracellular matrix production in vitro. Journal of Cellular Biochemistry. 97: 423-32. PMID 16211577 DOI: 10.1002/Jcb.20654  0.506
2005 Yan Q, Perdue N, Blake D, Sage EH. Absence of SPARC in murine lens epithelium leads to increased deposition of laminin-1 in lens capsule. Investigative Ophthalmology & Visual Science. 46: 4652-60. PMID 16303962 DOI: 10.1167/Iovs.05-0460  0.38
2005 Wang H, Fertala A, Ratner BD, Sage EH, Jiang S. Identifying the SPARC binding sites on collagen I and procollagen I by atomic force microscopy. Analytical Chemistry. 77: 6765-71. PMID 16255572 DOI: 10.1021/Ac051349D  0.332
2005 Barker TH, Baneyx G, Cardó-Vila M, Workman GA, Weaver M, Menon PM, Dedhar S, Rempel SA, Arap W, Pasqualini R, Vogel V, Sage EH. SPARC regulates extracellular matrix organization through its modulation of integrin-linked kinase activity. The Journal of Biological Chemistry. 280: 36483-93. PMID 16115889 DOI: 10.1074/Jbc.M504663200  0.418
2005 Yan Q, Perdue N, Sage EH. Differential responses of human lens epithelial cells to intraocular lenses in vitro: hydrophobic acrylic versus PMMA or silicone discs. Graefe's Archive For Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv FüR Klinische Und Experimentelle Ophthalmologie. 243: 1253-62. PMID 15909158 DOI: 10.1007/S00417-005-1181-2  0.371
2005 Gruber HE, Sage EH, Norton HJ, Funk S, Ingram J, Hanley EN. Targeted deletion of the SPARC gene accelerates disc degeneration in the aging mouse. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 53: 1131-8. PMID 15879573 DOI: 10.1369/Jhc.5A6687.2005  0.393
2005 Puolakkainen PA, Bradshaw AD, Brekken RA, Reed MJ, Kyriakides T, Funk SE, Gooden MD, Vernon RB, Wight TN, Bornstein P, Sage EH. SPARC-thrombospondin-2-double-null mice exhibit enhanced cutaneous wound healing and increased fibrovascular invasion of subcutaneous polyvinyl alcohol sponges. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 53: 571-81. PMID 15872050 DOI: 10.1369/Jhc.4A6425.2005  0.662
2005 Reed MJ, Bradshaw AD, Shaw M, Sadoun E, Han N, Ferara N, Funk S, Puolakkainen P, Sage EH. Enhanced angiogenesis characteristic of SPARC-null mice disappears with age. Journal of Cellular Physiology. 204: 800-7. PMID 15795937 DOI: 10.1002/jcp.20348  0.639
2005 Barker TH, Framson P, Puolakkainen PA, Reed M, Funk SE, Sage EH. Matricellular homologs in the foreign body response: hevin suppresses inflammation, but hevin and SPARC together diminish angiogenesis. The American Journal of Pathology. 166: 923-33. PMID 15743803 DOI: 10.1016/S0002-9440(10)62312-7  0.413
2005 Yan Q, Weaver M, Perdue N, Sage EH. Matricellular protein SPARC is translocated to the nuclei of immortalized murine lens epithelial cells. Journal of Cellular Physiology. 203: 286-94. PMID 15534859 DOI: 10.1002/Jcp.20226  0.443
2004 Aycock RL, Bradshaw AC, Sage EH, Starcher B. Development of UV-induced squamous cell carcinomas is suppressed in the absence of SPARC. The Journal of Investigative Dermatology. 123: 592-9. PMID 15304102 DOI: 10.1111/J.0022-202X.2004.23316.X  0.382
2004 Framson PE, Sage EH. SPARC and tumor growth: where the seed meets the soil? Journal of Cellular Biochemistry. 92: 679-90. PMID 15211566 DOI: 10.1002/Jcb.20091  0.4
2004 Brekken RA, Sullivan MM, Workman G, Bradshaw AD, Carbon J, Siadak A, Murri C, Framson PE, Sage EH. Expression and characterization of murine hevin (SC1), a member of the SPARC family of matricellular proteins. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 52: 735-48. PMID 15150282 DOI: 10.1369/Jhc.3A6245.2004  0.708
2004 Sweetwyne MT, Brekken RA, Workman G, Bradshaw AD, Carbon J, Siadak AW, Murri C, Sage EH. Functional analysis of the matricellular protein SPARC with novel monoclonal antibodies. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 52: 723-33. PMID 15150281 DOI: 10.1369/Jhc.3A6153.2004  0.663
2004 Sullivan MM, Sage EH. Hevin/SC1, a matricellular glycoprotein and potential tumor-suppressor of the SPARC/BM-40/Osteonectin family. The International Journal of Biochemistry & Cell Biology. 36: 991-6. PMID 15094114 DOI: 10.1016/J.Biocel.2004.01.017  0.405
2004 Francki A, McClure TD, Brekken RA, Motamed K, Murri C, Wang T, Sage EH. SPARC regulates TGF-beta1-dependent signaling in primary glomerular mesangial cells. Journal of Cellular Biochemistry. 91: 915-25. PMID 15034927 DOI: 10.1002/Jcb.20008  0.352
2004 Järveläinen H, Vernon RB, Gooden MD, Francki A, Lara S, Johnson PY, Kinsella MG, Sage EH, Wight TN. Overexpression of decorin by rat arterial smooth muscle cells enhances contraction of type I collagen in vitro. Arteriosclerosis, Thrombosis, and Vascular Biology. 24: 67-72. PMID 14615389 DOI: 10.1161/01.Atv.0000107026.98626.3B  0.353
2003 Sage EH. Purification of SPARC/osteonectin. Current Protocols in Cell Biology / Editorial Board, Juan S. Bonifacino ... [Et Al.]. Unit 10.11. PMID 18228415 DOI: 10.1002/0471143030.cb1011s17  0.345
2003 Rhee DJ, Fariss RN, Brekken R, Sage EH, Russell P. The matricellular protein SPARC is expressed in human trabecular meshwork. Experimental Eye Research. 77: 601-7. PMID 14550402 DOI: 10.1016/S0014-4835(03)00190-8  0.372
2003 Motamed K, Blake DJ, Angello JC, Allen BL, Rapraeger AC, Hauschka SD, Sage EH. Fibroblast growth factor receptor-1 mediates the inhibition of endothelial cell proliferation and the promotion of skeletal myoblast differentiation by SPARC: a role for protein kinase A. Journal of Cellular Biochemistry. 90: 408-23. PMID 14505356 DOI: 10.1002/Jcb.10645  0.433
2003 Sage EH, Reed M, Funk SE, Truong T, Steadele M, Puolakkainen P, Maurice DH, Bassuk JA. Cleavage of the matricellular protein SPARC by matrix metalloproteinase 3 produces polypeptides that influence angiogenesis. The Journal of Biological Chemistry. 278: 37849-57. PMID 12867428 DOI: 10.1074/Jbc.M302946200  0.395
2003 Delany AM, Kalajzic I, Bradshaw AD, Sage EH, Canalis E. Osteonectin-null mutation compromises osteoblast formation, maturation, and survival. Endocrinology. 144: 2588-96. PMID 12746322 DOI: 10.1210/En.2002-221044  0.663
2003 Bradshaw AD, Graves DC, Motamed K, Sage EH. SPARC-null mice exhibit increased adiposity without significant differences in overall body weight. Proceedings of the National Academy of Sciences of the United States of America. 100: 6045-50. PMID 12721366 DOI: 10.1073/pnas.1030790100  0.639
2003 Taneda S, Pippin JW, Sage EH, Hudkins KL, Takeuchi Y, Couser WG, Alpers CE. Amelioration of diabetic nephropathy in SPARC-null mice. Journal of the American Society of Nephrology : Jasn. 14: 968-80. PMID 12660331 DOI: 10.1097/01.Asn.0000054498.83125.90  0.377
2003 Yan Q, Blake D, Clark JI, Sage EH. Expression of the matricellular protein SPARC in murine lens: SPARC is necessary for the structural integrity of the capsular basement membrane. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 51: 503-11. PMID 12642629 DOI: 10.1177/002215540305100412  0.482
2003 Brekken RA, Puolakkainen P, Graves DC, Workman G, Lubkin SR, Sage EH. Enhanced growth of tumors in SPARC null mice is associated with changes in the ECM. The Journal of Clinical Investigation. 111: 487-95. PMID 12588887 DOI: 10.1172/Jci16804  0.395
2003 Francki A, Motamed K, McClure TD, Kaya M, Murri C, Blake DJ, Carbon JG, Sage EH. SPARC regulates cell cycle progression in mesangial cells via its inhibition of IGF-dependent signaling. Journal of Cellular Biochemistry. 88: 802-11. PMID 12577314 DOI: 10.1002/Jcb.10424  0.424
2003 Puolakkainen P, Bradshaw AD, Kyriakides TR, Reed M, Brekken R, Wight T, Bornstein P, Ratner B, Sage EH. Compromised production of extracellular matrix in mice lacking secreted protein, acidic and rich in cysteine (SPARC) leads to a reduced foreign body reaction to implanted biomaterials. The American Journal of Pathology. 162: 627-35. PMID 12547720 DOI: 10.1016/S0002-9440(10)63856-4  0.653
2003 Reed MJ, Koike T, Sadoun E, Sage EH, Puolakkainen P. Inhibition of TIMP1 enhances angiogenesis in vivo and cell migration in vitro. Microvascular Research. 65: 9-17. PMID 12535866 DOI: 10.1016/S0026-2862(02)00026-2  0.425
2003 Sage EH, Bradshaw AD, Brekken R. SPARC, a Matricellular Protein That Regulates Cell-Matrix Interaction: Implications for Vascular and Connective Tissue Biology Extracellular Matrix and the Liver: Approach to Gene Therapy. 75-85. DOI: 10.1016/B978-012525251-5/50006-3  0.322
2002 Alpers CE, Hudkins KL, Segerer S, Sage EH, Pichler R, Couser WG, Johnson RJ, Bassuk JA. Localization of SPARC in developing, mature, and chronically injured human allograft kidneys. Kidney International. 62: 2073-86. PMID 12427131 DOI: 10.1046/J.1523-1755.2002.00680.X  0.417
2002 Bornstein P, Sage EH. Matricellular proteins: extracellular modulators of cell function. Current Opinion in Cell Biology. 14: 608-16. PMID 12231357 DOI: 10.1016/S0955-0674(02)00361-7  0.43
2002 Netherton SJ, Jimmo SL, Palmer D, Tilley DG, Dunkerley HA, Raymond DR, Russell JC, Absher PM, Sage EH, Vernon RB, Maurice DH. Altered phosphodiesterase 3-mediated cAMP hydrolysis contributes to a hypermotile phenotype in obese JCR:LA-cp rat aortic vascular smooth muscle cells: implications for diabetes-associated cardiovascular disease. Diabetes. 51: 1194-200. PMID 11916944 DOI: 10.2337/Diabetes.51.4.1194  0.31
2002 Motamed K, Funk SE, Koyama H, Ross R, Raines EW, Sage EH. Inhibition of PDGF-stimulated and matrix-mediated proliferation of human vascular smooth muscle cells by SPARC is independent of changes in cell shape or cyclin-dependent kinase inhibitors. Journal of Cellular Biochemistry. 84: 759-71. PMID 11835401 DOI: 10.1002/Jcb.10095  0.432
2002 Bradshaw AD, Reed MJ, Sage EH. SPARC-null mice exhibit accelerated cutaneous wound closure. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 50: 1-10. PMID 11748289 DOI: 10.1177/002215540205000101  0.668
2001 Bradshaw AD, Reed MJ, Carbon JG, Pinney E, Brekken RA, Sage EH. Increased fibrovascular invasion of subcutaneous polyvinyl alcohol sponges in SPARC-null mice. Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society. 9: 522-30. PMID 11896995 DOI: 10.1046/J.1524-475X.2001.00522.X  0.687
2001 Francki A, Sage EH. SPARC and the kidney glomerulus: matricellular proteins exhibit diverse functions under normal and pathological conditions. Trends in Cardiovascular Medicine. 11: 32-7. PMID 11413050  0.318
2001 Bradshaw AD, Sage EH. SPARC, a matricellular protein that functions in cellular differentiation and tissue response to injury. The Journal of Clinical Investigation. 107: 1049-54. PMID 11342565 DOI: 10.1172/Jci12939  0.683
2001 Sage EH. Regulation of interactions between cells and extracellular matrix: a command performance on several stages. The Journal of Clinical Investigation. 107: 781-3. PMID 11285292 DOI: 10.1172/Jci12683  0.496
2001 Yan Q, Li Y, Hendrickson A, Sage EH. Regulation of retinal capillary cells by basic fibroblast growth factor, vascular endothelial growth factor, and hypoxia. In Vitro Cellular & Developmental Biology. Animal. 37: 45-9. PMID 11249204 DOI: 10.1290/1071-2690(2001)037<0045:Rorccb>2.0.Co;2  0.403
2001 Brekken RA, Sage EH. SPARC, a matricellular protein: at the crossroads of cell-matrix communication. Matrix Biology : Journal of the International Society For Matrix Biology. 19: 816-27. PMID 11223341 DOI: 10.1016/s0945-053x(00)00133-5  0.398
2001 Brekken RA, Sage EH. SPARC, a matricellular protein: at the crossroads of cell-matrix. Matrix Biology : Journal of the International Society For Matrix Biology. 19: 569-80. PMID 11102747 DOI: 10.1016/S0945-053X(00)00105-0  0.496
2000 Bradshaw AD, Bassuk JA, Francki A, Sage EH. Expression and purification of recombinant human SPARC produced by baculovirus. Molecular Cell Biology Research Communications : McBrc. 3: 345-51. PMID 11032756 DOI: 10.1006/Mcbr.2000.0237  0.695
2000 Norose K, Lo WK, Clark JI, Sage EH, Howe CC. Lenses of SPARC-null mice exhibit an abnormal cell surface-basement membrane interface. Experimental Eye Research. 71: 295-307. PMID 10973738 DOI: 10.1006/Exer.2000.0884  0.412
2000 Gilbert RE, Cox AJ, Kelly DJ, Wilkinson-Berka JL, Sage EH, Jerums G, Cooper ME. Localization of secreted protein acidic and rich in cysteine (SPARC) expression in the rat eye. Connective Tissue Research. 40: 295-303. PMID 10757117 DOI: 10.3109/03008209909000707  0.44
2000 Bassuk JA, Pichler R, Rothmier JD, Pippen J, Gordon K, Meek RL, Bradshaw AD, Lombardi D, Strandjord TP, Reed M, Sage EH, Couser WG, Johnson R. Induction of TGF-beta1 by the matricellular protein SPARC in a rat model of glomerulonephritis. Kidney International. 57: 117-28. PMID 10620193 DOI: 10.1046/J.1523-1755.2000.00811.X  0.585
1999 Yan Q, Sage EH. SPARC, a matricellular glycoprotein with important biological functions. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 47: 1495-506. PMID 10567433 DOI: 10.1177/002215549904701201  0.482
1999 Francki A, Bradshaw AD, Bassuk JA, Howe CC, Couser WG, Sage EH. SPARC regulates the expression of collagen type I and transforming growth factor-beta1 in mesangial cells. The Journal of Biological Chemistry. 274: 32145-52. PMID 10542250 DOI: 10.1074/Jbc.274.45.32145  0.691
1999 Puolakkainen P, Reed M, Vento P, Sage EH, Kiviluoto T, Kivilaakso E. Expression of SPARC (secreted protein, acidic and rich in cysteine) in healing intestinal anastomoses and short bowel syndrome in rats. Digestive Diseases and Sciences. 44: 1554-64. PMID 10492132 DOI: 10.1023/A:1026602708263  0.402
1999 Strandjord TP, Madtes DK, Weiss DJ, Sage EH. Collagen accumulation is decreased in SPARC-null mice with bleomycin-induced pulmonary fibrosis. The American Journal of Physiology. 277: L628-35. PMID 10484471 DOI: 10.1152/Ajplung.1999.277.3.L628  0.422
1999 Huynh MH, Sage EH, Ringuette M. A calcium-binding motif in SPARC/osteonectin inhibits chordomesoderm cell migration during Xenopus laevis gastrulation: evidence of counter-adhesive activity in vivo. Development, Growth & Differentiation. 41: 407-18. PMID 10466928 DOI: 10.1046/J.1440-169X.1999.00443.X  0.345
1999 Boehm JR, Kutz SM, Sage EH, Staiano-Coico L, Higgins PJ. Growth state-dependent regulation of plasminogen activator inhibitor type-1 gene expression during epithelial cell stimulation by serum and transforming growth factor-beta1. Journal of Cellular Physiology. 181: 96-106. PMID 10457357 DOI: 10.1002/(Sici)1097-4652(199910)181:1<96::Aid-Jcp10>3.0.Co;2-I  0.388
1999 Gooden MD, Vernon RB, Bassuk JA, Sage EH. Cell cycle-dependent nuclear location of the matricellular protein SPARC: association with the nuclear matrix. Journal of Cellular Biochemistry. 74: 152-67. PMID 10404386 DOI: 10.1002/(SICI)1097-4644(19990801)74:2<152::AID-JCB2>3.0.CO;2-4  0.361
1999 Bradshaw AD, Francki A, Motamed K, Howe C, Sage EH. Primary mesenchymal cells isolated from SPARC-null mice exhibit altered morphology and rates of proliferation. Molecular Biology of the Cell. 10: 1569-79. PMID 10233163 DOI: 10.1091/Mbc.10.5.1569  0.688
1999 Bassuk JA, Birkebak T, Rothmier JD, Clark JM, Bradshaw A, Muchowski PJ, Howe CC, Clark JI, Sage EH. Disruption of the Sparc locus in mice alters the differentiation of lenticular epithelial cells and leads to cataract formation Experimental Eye Research. 68: 321-331. PMID 10079140 DOI: 10.1006/Exer.1998.0608  0.414
1999 Redlitz A, Daum G, Sage EH. Angiostatin diminishes activation of the mitogen-activated protein kinases ERK-1 and ERK-2 in human dermal microvascular endothelial cells. Journal of Vascular Research. 36: 28-34. PMID 10050071 DOI: 10.1159/000025623  0.325
1999 Vernon RB, Sage EH. A novel, quantitative model for study of endothelial cell migration and sprout formation within three-dimensional collagen matrices. Microvascular Research. 57: 118-33. PMID 10049660 DOI: 10.1006/Mvre.1998.2122  0.419
1998 Yan Q, Sage EH, Hendrickson AE. SPARC is expressed by ganglion cells and astrocytes in bovine retina. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 46: 3-10. PMID 10712100 DOI: 10.1177/002215549804600102  0.388
1998 Motamed K, Sage EH. SPARC inhibits endothelial cell adhesion but not proliferation through a tyrosine phosphorylation-dependent pathway. Journal of Cellular Biochemistry. 70: 543-52. PMID 9712151 DOI: 10.1002/(Sici)1097-4644(19980915)70:4<543::Aid-Jcb10>3.0.Co;2-I  0.396
1998 Bagavandoss P, Sage EH, Vernon RB. Secreted protein, acidic and rich in cysteine (SPARC) and thrombospondin in the developing follicle and corpus luteum of the rat. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 46: 1043-49. PMID 9705970 DOI: 10.1177/002215549804600908  0.452
1998 Arthur WT, Vernon RB, Sage EH, Reed MJ. Growth factors reverse the impaired sprouting of microvessels from aged mice. Microvascular Research. 55: 260-70. PMID 9657926 DOI: 10.1006/Mvre.1998.2078  0.384
1998 Yan Q, Sage EH. Transforming growth factor-beta1 induces apoptotic cell death in cultured retinal endothelial cells but not pericytes: association with decreased expression of p21waf1/cip1. Journal of Cellular Biochemistry. 70: 70-83. PMID 9632109 DOI: 10.1002/(Sici)1097-4644(19980701)70:1<70::Aid-Jcb8>3.0.Co;2-0  0.344
1998 Damjanovski S, Huynh MH, Motamed K, Sage EH, Ringuette M. Regulation of SPARC expression during early Xenopus development: evolutionary divergence and conservation of DNA regulatory elements between amphibians and mammals. Development Genes and Evolution. 207: 453-61. PMID 9510540 DOI: 10.1007/S004270050136  0.369
1997 Shankavaram UT, DeWitt DL, Funk SE, Sage EH, Wahl LM. Regulation of human monocyte matrix metalloproteinases by SPARC. Journal of Cellular Physiology. 173: 327-34. PMID 9369945 DOI: 10.1002/(Sici)1097-4652(199712)173:3<327::Aid-Jcp4>3.0.Co;2-P  0.356
1997 Soderling JA, Reed MJ, Corsa A, Sage EH. Cloning and expression of murine SC1, a gene product homologous to SPARC Journal of Histochemistry and Cytochemistry. 45: 823-435. PMID 9199668 DOI: 10.1177/002215549704500607  0.431
1997 Damjanovski S, Karp X, Funk S, Sage EH, Ringuette MJ. Ectopic expression of SPARC in Xenopus embryos interferes with tissue morphogenesis: identification of a bioactive sequence in the C-terminal EF hand. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 45: 643-55. PMID 9154151 DOI: 10.1177/002215549704500502  0.337
1997 Motamed K, Sage EH. Regulation of vascular morphogenesis by the matricellular protein SPARC. Kidney International. 51: 1383-7. PMID 9150448 DOI: 10.1038/Ki.1997.189  0.452
1997 Sibinga NE, Foster LC, Hsieh CM, Perrella MA, Lee WS, Endege WO, Sage EH, Lee ME, Haber E. Collagen VIII is expressed by vascular smooth muscle cells in response to vascular injury. Circulation Research. 80: 532-41. PMID 9118484 DOI: 10.1161/01.Res.80.4.532  0.42
1997 Sage EH. Terms of attachment: SPARC and tumorigenesis. Nature Medicine. 3: 144-6. PMID 9018225 DOI: 10.1038/Nm0297-144  0.399
1997 Pichler RH, Hugo C, Shankland SJ, Reed MJ, Bassuk JA, Andoh TF, Lombardi DM, Schwartz SM, Bennett WM, Alpers CE, Sage EH, Johnson RJ, Couser WG. SPARC is expressed in renal interstitial fibrosis and in renal vascular injury. Kidney International. 50: 1978-89. PMID 8943481 DOI: 10.1038/Ki.1996.520  0.437
1997 Iruela-Arispe ML, Vernon RB, Wu H, Jaenisch R, Sage EH. Type I collagen-deficient Mov-13 mice do not retain SPARC in the extracellular matrix: implications for fibroblast function. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 207: 171-83. PMID 8906420 DOI: 10.1002/(Sici)1097-0177(199610)207:2<171::Aid-Aja5>3.0.Co;2-E  0.498
1996 Bassuk JA, Braun LP, Motamed K, Baneyx F, Sage EH. Renaturation of SPARC expressed in Escherichia coli requires isomerization of disulfide bonds for recovery of biological activity. The International Journal of Biochemistry & Cell Biology. 28: 1031-43. PMID 8930126 DOI: 10.1016/1357-2725(96)00036-2  0.432
1996 Luther T, Flössel C, Mackman N, Bierhaus A, Kasper M, Albrecht S, Sage EH, Iruela-Arispe L, Grossmann H, Ströhlein A, Zhang Y, Nawroth PP, Carmeliet P, Loskutoff DJ, Müller M. Tissue factor expression during human and mouse development. The American Journal of Pathology. 149: 101-13. PMID 8686734  0.708
1996 Vernon RB, Sage EH. Contraction of fibrillar type I collagen by endothelial cells: a study in vitro. Journal of Cellular Biochemistry. 60: 185-97. PMID 8655629 DOI: 10.1002/(Sici)1097-4644(19960201)60:2<185::Aid-Jcb3>3.0.Co;2-T  0.49
1996 Iruela-Arispe ML, Porter P, Bornstein P, Sage EH. Thrombospondin-1, an inhibitor of angiogenesis, is regulated by progesterone in the human endometrium. The Journal of Clinical Investigation. 97: 403-12. PMID 8567961 DOI: 10.1172/Jci118429  0.335
1996 Bassuk JA, Baneyx F, Vernon RB, Funk SE, Sage EH. Expression of biologically active human SPARC in Escherichia coli. Archives of Biochemistry and Biophysics. 325: 8-19. PMID 8554346 DOI: 10.1006/Abbi.1996.0002  0.403
1995 Puolakkainen PA, Reed MJ, Gombotz WR, Twardzik DR, Abrass IB, Sage EH. Acceleration of wound healing in aged rats by topical application of transforming growth factor-beta(1). Wound Repair and Regeneration. 3: 330-339. PMID 17173560 DOI: 10.1046/J.1524-475X.1995.T01-1-30314.X  0.351
1995 Porter PL, Sage EH, Lane TF, Funk SE, Gown AM. Distribution of SPARC in normal and neoplastic human tissue. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 43: 791-800. PMID 7622842 DOI: 10.1177/43.8.7622842  0.325
1995 Reed MJ, Iruela-Arispe L, O'Brien ER, Truong T, LaBell T, Bornstein P, Sage EH. Expression of thrombospondins by endothelial cells. Injury is correlated with TSP-1. The American Journal of Pathology. 147: 1068-80. PMID 7573352  0.737
1995 Seiffert D, Iruela-Arispe ML, Sage EH, Loskutoff DJ. Distribution of vitronectin mRNA during murine development. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 203: 71-9. PMID 7544171 DOI: 10.1002/Aja.1002030108  0.337
1995 Vernon RB, Lara SL, Drake CJ, Iruela-Arispe ML, Angello JC, Little CD, Wight TN, Sage EH. Organized type I collagen influences endothelial patterns during "spontaneous angiogenesis in vitro": planar cultures as models of vascular development. In Vitro Cellular & Developmental Biology. Animal. 31: 120-31. PMID 7537585 DOI: 10.1007/Bf02633972  0.417
1995 Frizell E, Liu S, Abraham A, Ozaki I, Eghbali M, Sage EH, Zern MA. Expression of SPARC in normal and fibrotic livers Hepatology. 21: 847-854. DOI: 10.1002/Hep.1840210335  0.402
1994 Reed MJ, Vernon RB, Abrass IB, Sage EH. TGF-beta 1 induces the expression of type I collagen and SPARC, and enhances contraction of collagen gels, by fibroblasts from young and aged donors. Journal of Cellular Physiology. 158: 169-79. PMID 8263022 DOI: 10.1002/Jcp.1041580121  0.398
1994 Goldblum SE, Ding X, Funk SE, Sage EH. SPARC (secreted protein acidic and rich in cysteine) regulates endothelial cell shape and barrier function. Proceedings of the National Academy of Sciences of the United States of America. 91: 3448-52. PMID 8159767 DOI: 10.1073/pnas.91.8.3448  0.321
1994 Yost JC, Bell A, Seale R, Sage EH. Purification of biologically active SPARC expressed in Saccharomyces cerevisiae. Archives of Biochemistry and Biophysics. 314: 50-63. PMID 7944407 DOI: 10.1006/abbi.1994.1411  0.365
1994 O'Reilly MS, Holmgren L, Shing Y, Chen C, Rosenthal RA, Moses M, Lane WS, Cao Y, Sage EH, Folkman J. Angiostatin: A novel angiogenesis inhibitor that mediates the suppression of metastases by a lewis lung carcinoma Cell. 79: 315-328. PMID 7525077 DOI: 10.1016/0092-8674(94)90200-3  0.314
1994 Battegay EJ, Rupp J, Iruela-Arispe L, Sage EH, Pech M. PDGF-BB modulates endothelial proliferation and angiogenesis in vitro via PDGF beta-receptors. The Journal of Cell Biology. 125: 917-28. PMID 7514607 DOI: 10.1083/jcb.125.4.917  0.72
1993 Tremble PM, Lane TF, Sage EH, Werb Z. SPARC, a secreted protein associated with morphogenesis and tissue remodeling, induces expression of metalloproteinases in fibroblasts through a novel extracellular matrix-dependent pathway. The Journal of Cell Biology. 121: 1433-44. PMID 8509459 DOI: 10.1083/Jcb.121.6.1433  0.397
1993 Iruela-Arispe ML, Liska DJ, Sage EH, Bornstein P. Differential expression of thrombospondin 1, 2, and 3 during murine development. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 197: 40-56. PMID 8400410 DOI: 10.1002/Aja.1001970105  0.434
1993 Bassuk JA, Iruela-Arispe ML, Lane TF, Benson JM, Berg RA, Sage EH. Molecular analysis of chicken embryo SPARC (osteonectin). Febs Journal. 218: 117-127. PMID 7916692 DOI: 10.1111/J.1432-1033.1993.Tb18358.X  0.347
1993 Iruela-Arispe ML, Sage EH. Endothelial cells exhibiting angiogenesis in vitro proliferate in response to TGF-beta 1. Journal of Cellular Biochemistry. 52: 414-30. PMID 7693728 DOI: 10.1002/Jcb.240520406  0.401
1993 Järveläinen HT, Iruela-Arispe ML, Kinsella MG, Sandell LJ, Sage EH, Wight TN. Expression of decorin by sprouting bovine aortic endothelial cells exhibiting angiogenesis in vitro. Experimental Cell Research. 203: 395-401. PMID 1281110 DOI: 10.1016/0014-4827(92)90013-X  0.461
1992 Hasselaar P, Sage EH. SPARC antagonizes the effect of basic fibroblast growth factor on the migration of bovine aortic endothelial cells. Journal of Cellular Biochemistry. 49: 272-83. PMID 1644864 DOI: 10.1002/Jcb.240490310  0.466
1992 Sage EH. Modulation of endothelial cell shape by SPARC does not involve chelation of extracellular Ca2+ and Mg2+. Biochemistry and Cell Biology. 70: 56-62. PMID 1581032 DOI: 10.1139/O92-008  0.354
1992 Sage EH. Secretion of SPARC by endothelial cells transformed by polyoma middle T oncogene inhibits the growth of normal endothelial cells in vitro. Biochemistry and Cell Biology. 70: 579-592. PMID 1449724 DOI: 10.1139/O92-089  0.401
1992 Everitt EA, Sage EH. Expression of SPARC is correlated with altered morphologies in transfected F9 embryonal carcinoma cells. Experimental Cell Research. 199: 134-146. PMID 1310471 DOI: 10.1016/0014-4827(92)90471-J  0.4
1992 Everitt EA, Sage EH. Overexpression of SPARC in stably transfected F9 cells mediates attachment and spreading in Ca2+-deficient medium Biochemistry and Cell Biology. 70: 1368-1379. PMID 1299273 DOI: 10.1139/O92-185  0.332
1992 Iruela-Arispe ML, Chun LE, Sage EH. Structure and Biology of Type VIII Collagen. Trends in Glycoscience and Glycotechnology. 4: 188-199. DOI: 10.4052/Tigg.4.188  0.303
1991 Fouser L, Sage EH, Clark J, Bornstein P. Feedback regulation of collagen gene expression: a Trojan horse approach. Proceedings of the National Academy of Sciences of the United States of America. 88: 10158-62. PMID 1946435 DOI: 10.1073/Pnas.88.22.10158  0.32
1991 Fouser L, Iruela-Arispe L, Bornstein P, Sage EH. Transcriptional activity of the alpha 1(I)-collagen promoter is correlated with the formation of capillary-like structures by endothelial cells in vitro. The Journal of Biological Chemistry. 266: 18345-51. PMID 1917959  0.73
1991 Iruela-Arispe ML, Sage EH. Expression of type VIII collagen during morphogenesis of the chicken and mouse heart. Developmental Biology. 144: 107-18. PMID 1847345 DOI: 10.1016/0012-1606(91)90483-J  0.353
1991 Iruela-Arispe ML, Diglio CA, Sage EH. Modulation of extracellular matrix proteins by endothelial cells undergoing angiogenesis in vitro. Arteriosclerosis and Thrombosis : a Journal of Vascular Biology. 11: 805-15. PMID 1712229 DOI: 10.1161/01.ATV.11.4.805  0.396
1977 Sage EH, Gray WR. Evolution of elastin structure. Advances in Experimental Medicine and Biology. 79: 291-312. PMID 868643  0.465
Low-probability matches (unlikely to be authored by this person)
1997 Rosenblatt S, Bassuk JA, Alpers CE, Sage EH, Timpl R, Preissner KT. Differential modulation of cell adhesion by interaction between adhesive and counter-adhesive proteins: characterization of the binding of vitronectin to osteonectin (BM40, SPARC). The Biochemical Journal. 324: 311-9. PMID 9164872 DOI: 10.1042/bj3240311  0.298
1992 Raines EW, Lane TF, Iruela-Arispe ML, Ross R, Sage EH. The extracellular glycoprotein SPARC interacts with platelet-derived growth factor (PDGF)-AB and -BB and inhibits the binding of PDGF to its receptors. Proceedings of the National Academy of Sciences of the United States of America. 89: 1281-5. PMID 1311092 DOI: 10.1073/Pnas.89.4.1281  0.294
1993 Funk SE, Sage EH. Differential effects of SPARC and cationic SPARC peptides on DNA synthesis by endothelial cells and fibroblasts. Journal of Cellular Physiology. 154: 53-63. PMID 8419407 DOI: 10.1002/jcp.1041540108  0.291
2007 Weaver MS, Toida N, Sage EH. Expression of integrin-linked kinase in the murine lens is consistent with its role in epithelial-mesenchymal transition of lens epithelial cells in vitro. Molecular Vision. 13: 707-18. PMID 17563721  0.289
2009 Zhang J, Gratchev A, Riabov V, Mamidi S, Schmuttermaier C, Krusell L, Kremmer E, Workman G, Sage EH, Jalkanen S, Goerdt S, Kzhyshkowska J. A novel GGA-binding site is required for intracellular sorting mediated by stabilin-1. Molecular and Cellular Biology. 29: 6097-105. PMID 19752197 DOI: 10.1128/Mcb.00505-09  0.287
2000 Parsons-Wingerter P, Elliott KE, Farr AG, Radhakrishnan K, Clark JI, Sage EH. Generational analysis reveals that TGF-beta1 inhibits the rate of angiogenesis in vivo by selective decrease in the number of new vessels. Microvascular Research. 59: 221-32. PMID 10684728 DOI: 10.1006/Mvre.1999.2213  0.284
2000 Paley PJ, Goff BA, Gown AM, Greer BE, Sage EH. Alterations in SPARC and VEGF immunoreactivity in epithelial ovarian cancer. Gynecologic Oncology. 78: 336-41. PMID 10985890 DOI: 10.1006/gyno.2000.5894  0.283
1995 Iruela-Arispe ML, Lane TF, Redmond D, Reilly M, Bolender RP, Kavanagh TJ, Sage EH. Expression of SPARC during development of the chicken chorioallantoic membrane: Evidence for regulated proteolysis in vivo Molecular Biology of the Cell. 6: 327-343. PMID 7612967 DOI: 10.1091/mbc.6.3.327  0.282
1994 Liska DJ, Reed MJ, Sage EH, Bornstein P. Cell-specific expression of α1(I) collagen-hGH minigenes in transgenic mice Journal of Cell Biology. 125: 695-704. PMID 8175887 DOI: 10.1083/Jcb.125.3.695  0.281
2011 Millecamps M, Tajerian M, Sage EH, Stone LS. Behavioral signs of chronic back pain in the SPARC-null mouse. Spine. 36: 95-102. PMID 20714283 DOI: 10.1097/Brs.0B013E3181Cd9D75  0.279
2007 Chen N, Ye XC, Chu K, Navone NM, Sage EH, Yu-Lee LY, Logothetis CJ, Lin SH. A secreted isoform of ErbB3 promotes osteonectin expression in bone and enhances the invasiveness of prostate cancer cells. Cancer Research. 67: 6544-8. PMID 17638862 DOI: 10.1158/0008-5472.Can-07-1330  0.278
2008 Haber CL, Gottifredi V, Llera AS, Salvatierra E, Prada F, Alonso L, Sage EH, Helene SE, Podhajcer OL. SPARC modulates the proliferation of stromal but not melanoma cells unless endogenous SPARC expression is downregulated. International Journal of Cancer. Journal International Du Cancer. 122: 1465-75. PMID 18059024 DOI: 10.1002/ijc.23216  0.276
2008 Liu L, Chen G, Chao T, Ratner BD, Sage EH, Jiang S. Reduced foreign body reaction to implanted biomaterials by surface treatment with oriented osteopontin. Journal of Biomaterials Science. Polymer Edition. 19: 821-35. PMID 18534099 DOI: 10.1163/156856208784522083  0.275
1993 Reed MJ, Puolakkainen P, Lane TF, Dickerson D, Bornstein P, Sage EH. Differential expression of SPARC and thrombospondin 1 in wound repair: immunolocalization and in situ hybridization. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 41: 1467-77. PMID 8245406 DOI: 10.1177/41.10.8245406  0.274
2002 Avakian A, Kalina RE, Sage EH, Rambhia AH, Elliott KE, Chuang EL, Clark JI, Hwang JN, Parsons-Wingerter P. Fractal analysis of region-based vascular change in the normal and non-proliferative diabetic retina. Current Eye Research. 24: 274-80. PMID 12324866 DOI: 10.1076/Ceyr.24.4.274.8411  0.273
1991 Funk SE, Sage EH. The Ca2(+)-binding glycoprotein SPARC modulates cell cycle progression in bovine aortic endothelial cells. Proceedings of the National Academy of Sciences of the United States of America. 88: 2648-52. PMID 2011576 DOI: 10.1073/pnas.88.7.2648  0.27
2004 Gongidi V, Ring C, Moody M, Brekken R, Sage EH, Rakic P, Anton ES. SPARC-like 1 regulates the terminal phase of radial glia-guided migration in the cerebral cortex. Neuron. 41: 57-69. PMID 14715135 DOI: 10.1016/S0896-6273(03)00818-3  0.27
1988 Kapoor R, Sakai LY, Funk S, Roux E, Bornstein P, Sage EH. Type VIII collagen has a restricted distribution in specialized extracellular matrices. The Journal of Cell Biology. 107: 721-30. PMID 3047147 DOI: 10.1083/Jcb.107.2.721  0.269
1998 Kupprion C, Motamed K, Sage EH. SPARC (BM-40, osteonectin) inhibits the mitogenic effect of vascular endothelial growth factor on microvascular endothelial cells. The Journal of Biological Chemistry. 273: 29635-40. PMID 9792673 DOI: 10.1074/jbc.273.45.29635  0.267
1998 Parsons-Wingerter P, Lwai B, Yang MC, Elliott KE, Milaninia A, Redlitz A, Clark JI, Sage EH. A novel assay of angiogenesis in the quail chorioallantoic membrane: stimulation by bFGF and inhibition by angiostatin according to fractal dimension and grid intersection. Microvascular Research. 55: 201-14. PMID 9657920 DOI: 10.1006/Mvre.1998.2073  0.265
2005 Lubkin SR, Funk SE, Sage EH. Quantifying vasculature: New measures applied to arterial trees in the quail chorioallantoic membrane Journal of Theoretical Medicine. 6: 173-180. DOI: 10.1080/10273660500264684  0.264
2000 Yan Q, Clark JI, Sage EH. Expression and characterization of SPARC in human lens and in the aqueous and vitreous humors. Experimental Eye Research. 71: 81-90. PMID 10880278 DOI: 10.1006/exer.2000.0853  0.262
2003 Koukourakis MI, Giatromanolaki A, Brekken RA, Sivridis E, Gatter KC, Harris AL, Sage EH. Enhanced expression of SPARC/osteonectin in the tumor-associated stroma of non-small cell lung cancer is correlated with markers of hypoxia/acidity and with poor prognosis of patients. Cancer Research. 63: 5376-80. PMID 14500371  0.26
2007 Wang H, Ratner BD, Sage EH, Jiang S. Stepwise assembly of fibrin bilayers on self-assembled monolayers of alkanethiolates: Influence of surface chemistry Journal of Physical Chemistry C. 111: 8504-8508. DOI: 10.1021/Jp066960A  0.259
2007 Tian J, Paquette-Straub C, Sage EH, Funk SE, Patel V, Galileo D, McLane MA. Corrigendum to "Inhibition of melanoma cell motility by the snake venom disintegrin eristostatin". [Toxicon 49 (2007) 899-908] (DOI:10.1016/j.toxicon.2006.12.013) Toxicon. 50: 448. DOI: 10.1016/J.Toxicon.2007.05.006  0.257
2009 Swinnen M, Vanhoutte D, Van Almen GC, Hamdani N, Schellings MW, D'hooge J, Van der Velden J, Weaver MS, Sage EH, Bornstein P, Verheyen FK, VandenDriessche T, Chuah MK, Westermann D, Paulus WJ, et al. Absence of thrombospondin-2 causes age-related dilated cardiomyopathy. Circulation. 120: 1585-97. PMID 19805649 DOI: 10.1161/Circulationaha.109.863266  0.256
2008 Yuen J, Li Y, Shapiro LG, Clark JI, Arnett E, Sage EH, Brinkley JF. Automated, computerized, feature-based phenotype analysis of slit lamp images of the mouse lens. Experimental Eye Research. 86: 562-75. PMID 18304532 DOI: 10.1016/J.Exer.2007.11.019  0.253
2007 Lehmann S, O'Kelly J, Raynaud S, Funk SE, Sage EH, Koeffler HP. Common deleted genes in the 5q- syndrome: thrombocytopenia and reduced erythroid colony formation in SPARC null mice. Leukemia. 21: 1931-6. PMID 17625608 DOI: 10.1038/sj.leu.2404852  0.252
2004 Hirano S, Yonezawa T, Hasegawa H, Hattori S, Greenhill NS, Davis PF, Sage EH, Ninomiya Y. Astrocytes express type VIII collagen during the repair process of brain cold injury. Biochemical and Biophysical Research Communications. 317: 437-43. PMID 15063777 DOI: 10.1016/j.bbrc.2004.03.049  0.251
1994 Lane TF, Iruela-Arispe ML, Johnson RS, Sage EH. SPARC is a source of copper-binding peptides that stimulate angiogenesis. The Journal of Cell Biology. 125: 929-43. PMID 7514608 DOI: 10.1083/jcb.125.4.929  0.24
1999 Sage EH, Westerhof N, Sipkema P, Redlitz A, Daum G, Boer C, Scheffer G, Lange Jd, Hungerford J, Little C, Liu G, Shaw L, Heagerty A, Ohanian V, Ohanian J, et al. Journal of Vascular Research and the Internet Journal of Vascular Research. 36: 1-1. DOI: 10.1159/000025621  0.239
2013 Girard PM, Graindorge D, Smirnova V, Rigolet P, Francesconi S, Scanlon S, Sage E. Oxidative Stress in Mammalian Cells Impinges on the Cysteines Redox State of Human XRCC3 Protein and on Its Cellular Localization Plos One. 8. PMID 24116071 DOI: 10.1371/journal.pone.0075751  0.238
2007 Au E, Richter MW, Vincent AJ, Tetzlaff W, Aebersold R, Sage EH, Roskams AJ. SPARC from olfactory ensheathing cells stimulates Schwann cells to promote neurite outgrowth and enhances spinal cord repair. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 7208-21. PMID 17611274 DOI: 10.1523/Jneurosci.0509-07.2007  0.236
2004 Puolakkainen PA, Brekken RA, Muneer S, Sage EH. Enhanced growth of pancreatic tumors in SPARC-null mice is associated with decreased deposition of extracellular matrix and reduced tumor cell apoptosis. Molecular Cancer Research : McR. 2: 215-24. PMID 15140943  0.233
1995 Strandjord TP, Sage EH, Clark JG. SPARC participates in the branching morphogenesis of developing fetal rat lung. American Journal of Respiratory Cell and Molecular Biology. 13: 279-87. PMID 7654384 DOI: 10.1165/ajrcmb.13.3.7654384  0.23
2012 Giangreco A, Lu L, Vickers C, Teixeira VH, Groot KR, Butler CR, Ilieva EV, George PJ, Nicholson AG, Sage EK, Watt FM, Janes SM. β-Catenin determines upper airway progenitor cell fate and preinvasive squamous lung cancer progression by modulating epithelial-mesenchymal transition Journal of Pathology. 226: 575-587. PMID 22081448 DOI: 10.1002/path.3962  0.228
1995 O'Reilly MS, Holmgren L, Shing Y, Chen C, Rosenthal RA, Cao Y, Moses M, Lane WS, Sage EH, Folkman J. Angiostatin: a circulating endothelial cell inhibitor that suppresses angiogenesis and tumor growth. Cold Spring Harbor Symposia On Quantitative Biology. 59: 471-82. PMID 7587101 DOI: 10.1101/SQB.1994.059.01.052  0.228
2015 Lathrop MJ, Sage EK, Macura SL, Brooks EM, Cruz F, Bonenfant NR, Sokocevic D, MacPherson MB, Beuschel SL, Dunaway CW, Shukla A, Janes SM, Steele C, Mossman BT, Weiss DJ. Antitumor effects of TRAIL-expressing mesenchymal stromal cells in a mouse xenograft model of human mesothelioma. Cancer Gene Therapy. 22: 44-54. PMID 25525034 DOI: 10.1038/Cgt.2014.68  0.225
2003 De S, Chen J, Narizhneva NV, Heston W, Brainard J, Sage EH, Byzova TV. Molecular pathway for cancer metastasis to bone. The Journal of Biological Chemistry. 278: 39044-50. PMID 12885781 DOI: 10.1074/Jbc.M304494200  0.222
1991 Lane TF, Sage EH. Functional mapping of SPARC: peptides from two distinct Ca+(+)-binding sites modulate cell shape. The Journal of Cell Biology. 111: 3065-76. PMID 2269665 DOI: 10.1083/jcb.111.6.3065  0.219
2008 López Haber C, Gottifredi V, Llera AS, Salvatierra E, Prada F, Alonso L, Sage EH, Podhacjer OL. SPARC modulates the proliferation of stromal but not melanoma cells unless endogenous SPARC expression is downregulated (International Journal of Cancer (2008) 122, (1465-1475)) International Journal of Cancer. 123: 245. DOI: 10.1002/ijc.23604  0.216
2013 Bracchitta G, Catalfo A, Martineau S, Sage E, De Guidi G, Girard PM. Investigation of the phototoxicity and cytotoxicity of naproxen, a non-steroidal anti-inflammatory drug, in human fibroblasts Photochemical and Photobiological Sciences. 12: 911-922. PMID 23478633 DOI: 10.1039/c3pp25326k  0.213
2014 Sage EK, Kolluri KK, McNulty K, Lourenco SDS, Kalber TL, Ordidge KL, Davies D, Lee YCG, Giangreco A, Janes SM. Systemic but not topical TRAIL-expressing mesenchymal stem cells reduce tumour growth in malignant mesothelioma Thorax. 69: 638-647. PMID 24567297 DOI: 10.1136/thoraxjnl-2013-204110  0.198
1999 Strandjord TP, Madtes DK, Weiss DJ, Sage EH. Collagen accumulation is decreased in SPARC-null mice with bleomycin-induced pulmonary fibrosis. American Journal of Physiology. Lung Cellular and Molecular Physiology. 277: L628-L635. PMID 29592434 DOI: 10.1152/ajplung.1999.277.3.L628  0.194
2002 Yan Q, Clark JI, Wight TN, Sage EH. Alterations in the lens capsule contribute to cataractogenesis in SPARC-null mice. Journal of Cell Science. 115: 2747-56. PMID 12077365  0.19
1991 Paulus W, Sage EH, Liszka U, Iruela-Arispe ML, Jellinger K. Increased levels of type VIII collagen in human brain tumours compared to normal brain tissue and non-neoplastic cerebral disorders. British Journal of Cancer. 63: 367-71. PMID 2003978 DOI: 10.1038/bjc.1991.87  0.176
2005 Kuypers FA, Watson G, Sage E, Walters MC, Hamrick J, Hearst JE. Stem cell transplantation with S-59 photochemically treated T-cell add-backs to establish allochimerism in murine thalassemia. Annals of the New York Academy of Sciences. 1054: 214-22. PMID 16339668 DOI: 10.1196/Annals.1345.026  0.17
2012 Bellini A, Girard PM, Lambert S, Tessier L, Sage E, Francesconi S. Stress Activated Protein Kinase Pathway Modulates Homologous Recombination in Fission Yeast Plos One. 7. PMID 23118915 DOI: 10.1371/journal.pone.0047987  0.17
2014 Bellini A, Girard PM, Tessier L, Sage E, Francesconi S. Fission yeast Rad52 phosphorylation restrains error prone recombination pathways Plos One. 9. PMID 24748152 DOI: 10.1371/journal.pone.0095788  0.167
2001 Roethy W, Fiehn E, Suehiro K, Gu A, Yi GH, Shimizu J, Wang J, Zhang G, Ranieri J, Akella R, Funk SE, Sage EH, Benedict J, Burkhoff D. A growth factor mixture that significantly enhances angiogenesis in vivo. The Journal of Pharmacology and Experimental Therapeutics. 299: 494-500. PMID 11602659  0.167
2012 Reagan MR, Philipp Seib F, McMillin DW, Sage EK, Mitsiades CS, Janes SM, Ghobrial IM, Kaplan DL. Stem cell implants for cancer therapy: TRAIL-expressing mesenchymal stem cells target cancer cells in situ Journal of Breast Cancer. 15: 273-282. DOI: 10.4048/jbc.2012.15.3.273  0.155
2014 Yuan ZQ, Kolluri KK, Sage EK, Gowers KHC, Janes SM. Mesenchymal stromal cell delivery of full-length tumor necrosis factor-related apoptosis-inducing ligand is superior to soluble type for cancer therapy Cytotherapy. DOI: 10.1016/j.jcyt.2015.03.603  0.153
1993 Sherratt JA, Sage EH, Murray JD. Chemical control of eukaryotic cell movement: a new model. Journal of Theoretical Biology. 162: 23-40. PMID 8412219 DOI: 10.1006/Jtbi.1993.1074  0.151
2010 Loebinger MR, Sage EK, Davies D, Janes SM. TRAIL-expressing mesenchymal stem cells kill the putative cancer stem cell population British Journal of Cancer. 103: 1692-1697. PMID 21063402 DOI: 10.1038/sj.bjc.6605952  0.147
2008 Sage E, Mercier O, Van den Eyden F, de Perrot M, Barlier-Mur AM, Dartevelle P, Eddahibi S, Herve P, Fadel E. Endothelial cell apoptosis in chronically obstructed and reperfused pulmonary artery Respiratory Research. 9. PMID 18269754 DOI: 10.1186/1465-9921-9-19  0.144
1996 Reed MJ, Sage EH. SPARC and the extracellular matrix: Implications for cancer and wound repair Current Topics in Microbiology and Immunology. 213: 81-94. PMID 8814996 DOI: 10.1007/978-3-642-61107-0_6  0.144
2010 Serrentino ME, Catalfo A, Angelin AR, de Guidi G, Sage E. Photosensitization induced by the antibacterial fluoroquinolone Rufloxacin leads to mutagenesis in yeast Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 692: 34-41. PMID 20696178 DOI: 10.1016/j.mrfmmm.2010.07.011  0.143
2007 Kabosova A, Azar DT, Bannikov GA, Campbell KP, Durbeej M, Ghohestani RF, Jones JC, Kenney MC, Koch M, Ninomiya Y, Patton BL, Paulsson M, Sado Y, Sage EH, Sasaki T, et al. Compositional differences between infant and adult human corneal basement membranes. Investigative Ophthalmology & Visual Science. 48: 4989-99. PMID 17962449 DOI: 10.1167/Iovs.07-0654  0.14
2004 Smales CM, Dinnis DM, Stansfield SH, Alete D, Sage EA, Birch JR, Racher AJ, Marshall CT, James DC. Comparative proteomic analysis of GS-NSO murine myeloma cell lines with varying recombinant monoclonal antibody production rate Biotechnology and Bioengineering. 88: 474-488. PMID 15459912 DOI: 10.1002/bit.20272  0.139
1994 Lane TF, Sage EH. The biology of SPARC, a protein that modulates cell‐matrix interactions The Faseb Journal. 8: 163-173. DOI: 10.1096/fasebj.8.2.8119487  0.138
2003 Rochette PJ, Therrien JP, Drouin R, Perdiz D, Bastien N, Drobetsky EA, Sage E. UVA-induced cyclobutane pyrimidine dimers form predominantly at thymine-thymine dipyrimidines and correlate with the mutation spectrum in rodent cells Nucleic Acids Research. 31: 2786-2794. PMID 12771205 DOI: 10.1093/Nar/Gkg402  0.138
2009 Kozmin SG, Sedletska Y, Reynaud-Angelin A, Gasparutto D, Sage E. The formation of double-strand breaks at multiply damaged sites is driven by the kinetics of excision/incision at base damage in eukaryotic cells Nucleic Acids Research. 37: 1767-1777. PMID 19174565 DOI: 10.1093/nar/gkp010  0.138
2014 Gehrmann M, Specht HM, Bayer C, Brandstetter M, Chizzali B, Duma M, Breuninger S, Hube K, Lehnerer S, van Phi V, Sage E, Schmid TE, Sedelmayr M, Schilling D, Sievert W, et al. Hsp70 - A biomarker for tumor detection and monitoring of outcome of radiation therapy in patients with squamous cell carcinoma of the head and neck Radiation Oncology. 9. PMID 24912482 DOI: 10.1186/1748-717X-9-131  0.137
2008 Girard PM, Pozzebon M, Delacôte F, Douki T, Smirnova V, Sage E. Inhibition of S-phase progression triggered by UVA-induced ROS does not require a functional DNA damage checkpoint response in mammalian cells Dna Repair. 7: 1500-1516. PMID 18603484 DOI: 10.1016/j.dnarep.2008.05.004  0.129
2008 Dardalhon D, Angelin AR, Baldacci G, Sage E, Francesconi S. Unconventional effects of UVA radiation on cell cycle progression in S. pombe Cell Cycle. 7: 611-622. PMID 18256544  0.129
2006 Reddy AB, Karp NA, Maywood ES, Sage EA, Deery M, O'Neill JS, Wong GK, Chesham J, Odell M, Lilley KS, Kyriacou CP, Hastings MH. Circadian orchestration of the hepatic proteome. Current Biology : Cb. 16: 1107-15. PMID 16753565 DOI: 10.1016/j.cub.2006.04.026  0.127
2012 Blouquit-Laye S, Dannhoffer L, Braun C, Dinh-Xuan AT, Sage E, Chinet T. Effect of nitric oxide on epithelial ion transports in noncystic fibrosis and cystic fibrosis human proximal and distal airways. American Journal of Physiology. Lung Cellular and Molecular Physiology. 303: L617-25. PMID 22773693 DOI: 10.1152/ajplung.00368.2011  0.122
2004 Budai M, Reynaud-Angelin A, Szabó Z, Tóth S, Rontó G, Sage E, Gróf P. Effect of UVA radiation on membrane fluidity and radical decay in human fibroblasts as detected by spin labeled stearic acids Journal of Photochemistry and Photobiology B: Biology. 77: 27-38. PMID 15542359 DOI: 10.1016/J.Jphotobiol.2004.08.003  0.119
2010 Grassin-Delyle S, Naline E, Buenestado A, Risse PA, Sage E, Advenier C, Devillier P. Expression and function of human hemokinin-1 in human and guinea pig airways Respiratory Research. 11. PMID 20929541 DOI: 10.1186/1465-9921-11-139  0.117
2006 Biade S, Marinucci M, Schick J, Roberts D, Workman G, Sage EH, O'Dwyer PJ, Livolsi VA, Johnson SW. Gene expression profiling of human ovarian tumours. British Journal of Cancer. 95: 1092-100. PMID 16969345 DOI: 10.1038/sj.bjc.6603346  0.116
2008 Usami N, Furusawa Y, Kobayashi K, Lacombe S, Reynaud-Angelin A, Sage E, Wu TD, Croisy A, Guerquin-Kern JL, Le Sech C. Mammalian cells loaded with platinum-containing molecules are sensitized to fast atomic ions International Journal of Radiation Biology. 84: 603-611. PMID 18661376 DOI: 10.1080/09553000802199846  0.116
2007 Éot-Houllier G, Gonera M, Gasparutto D, Giustranti C, Sage E. Interplay between DNA N-glycosylases/AP lyases at multiply damaged sites and biological consequences Nucleic Acids Research. 35: 3355-3366. PMID 17468500 DOI: 10.1093/nar/gkm190  0.115
2012 Sage E, Girard PM, Francesconi S. Unravelling UVA-induced mutagenesis Photochemical and Photobiological Sciences. 11: 74-80. PMID 21901217 DOI: 10.1039/c1pp05219e  0.115
2015 Miyara M, Chader D, Sage E, Sugiyama D, Nishikawa H, Bouvry D, Claër L, Hingorani R, Balderas R, Rohrer J, Warner N, Chapelier A, Valeyre D, Kannagi R, Sakaguchi S, et al. Sialyl Lewis x (CD15s) identifies highly differentiated and most suppressive FOXP3high regulatory T cells in humans Proceedings of the National Academy of Sciences of the United States of America. 112: 7225-7230. DOI: 10.1073/pnas.1508224112  0.114
2005 Eot-Houllier G, Eon-Marchais S, Gasparutto D, Sage E. Processing of a complex multiply damaged DNA site by human cell extracts and purified repair proteins Nucleic Acids Research. 33: 260-271. PMID 15647508 DOI: 10.1093/nar/gki165  0.11
2003 Kozmin SG, Pavlov YI, Kunkel TA, Sage E. Roles of Saccharomyces cerevisiae DNA polymerases Polη and Polζ in response to irridiation by simulated sunlight Nucleic Acids Research. 31: 4541-4552. PMID 12888515 DOI: 10.1093/Nar/Gkg489  0.109
2010 Hervé Du Penhoat MA, Eschenbrenner A, Abel F, Boissiere A, Guigner JM, Chetioui A, Politis MF, Touati A, Sage E, Jenner TJ, Stevens DL, Hill MA. Double-strand break induction and repair in V79-4 hamster cells: The role of core ionisations, as probed by ultrasoft X-rays International Journal of Radiation Biology. 86: 205-219. PMID 20201649 DOI: 10.3109/09553000903419296  0.108
2015 Nie J, Bradshaw AD, Delany AM, Sage EH. Correction to: Inactivation of SPARC enhances high fat diet-induced obesity in mice Connective Tissue Research. 56: 65. DOI: 10.3109/03008207.2014.947870  0.107
2004 Bos TJ, Cohn SL, Kleinman HK, Murphy-Ulrich JE, Podhajcer OL, Rempel SA, Rich JN, Rutka JT, Sage EH, Thompson EW. International Hermelin brain tumor symposium on matricellular proteins in normal and cancer cell-matrix interactions. Matrix Biology : Journal of the International Society For Matrix Biology. 23: 63-9. PMID 15230275 DOI: 10.1016/J.Matbio.2004.01.002  0.107
2011 Girard PM, Francesconi S, Pozzebon M, Graindorge D, Rochette P, Drouin R, Sage E. UVA-induced damage to DNA and proteins: Direct versus indirect photochemical processes Journal of Physics: Conference Series. 261. DOI: 10.1088/1742-6596/261/1/012002  0.101
2008 Loebinger MR, Sage EK, Janes SM. Mesenchymal stem cells as vectors for lung disease Proceedings of the American Thoracic Society. 5: 711-716. PMID 18684723 DOI: 10.1513/pats.200801-009AW  0.098
1995 Vento P, Kiviluoto T, Kivilaakso E, Reed M, Lehtonen E, Sage E, Puolakkainen P. Expression of TGF-β1 and SPARC in the healing of intestinal anastomoses and in short bowel syndrome Gastroenterology. 108: A761. DOI: 10.1016/0016-5085(95)27354-9  0.092
2005 Kozmin S, Slezak G, Reynaud-Angelin A, Elie C, De Rycke Y, Boiteux S, Sage E. UVA radiation is highly mutagenic in cells that are unable to repair 7,8-dihydro-8-oxoguanine in Saccharomyces cerevisiae Proceedings of the National Academy of Sciences of the United States of America. 102: 13538-13543. PMID 16157879 DOI: 10.1073/pnas.0504497102  0.092
2004 Boissiére A, Eschenbrenner A, Gobert F, Hervé du Penhoat MA, Abel F, Lamoureux M, Martins L, Politis MF, Ricoul M, Touati A, Sage E, Sabatier L, Chetioui A. Cellular inactivation and chromosomal aberrations: initial damage. Journal of Environmental Pathology, Toxicology and Oncology : Official Organ of the International Society For Environmental Toxicology and Cancer. 23: 107-15. PMID 15163289 DOI: 10.1615/JEnvPathToxOncol.v23.i2.30  0.089
2006 NIE J, SAGE E. SPARC inhibits adipogenesis Matrix Biology. 25: S86-S86. DOI: 10.1016/j.matbio.2006.08.237  0.088
2004 Marshall AJ, Barker T, Sage EH, Hauch KD, Ratner BD. Pore size controls angiogenesis in subcutaneously implanted porous matrices Transactions - 7th World Biomaterials Congress. 710.  0.085
2003 Douki T, Reynaud-Angelin A, Cadet J, Sage E. Bipyrimidine photoproducts rather than oxidative lesions are the main type of DNA damage involved in the genotoxic effect of solar UVA radiation Biochemistry. 42: 9221-9226. PMID 12885257 DOI: 10.1021/bi034593c  0.084
2011 Sage E, Harrison L. Clustered DNA lesion repair in eukaryotes: Relevance to mutagenesis and cell survival Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 711: 123-133. PMID 21185841 DOI: 10.1016/j.mrfmmm.2010.12.010  0.078
2013 Sedletska Y, Radicella JP, Sage E. Replication fork collapse is a major cause of the high mutation frequency at three-base lesion clusters Nucleic Acids Research. 41: 9339-9348. PMID 23945941 DOI: 10.1093/nar/gkt731  0.074
2005 Cadet J, Sage E, Douki T. Ultraviolet radiation-mediated damage to cellular DNA Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 571: 3-17. PMID 15748634 DOI: 10.1016/j.mrfmmm.2004.09.012  0.072
2006 Chen RL, Sage EA, Dunn MJ, Wait R, Preston JE. Optimising ovine cerebrospinal fluid preparation for two-dimensional gel electrophoresis. Proteomics. 6: 3170-5. PMID 16619304 DOI: 10.1002/pmic.200500623  0.07
2012 Buenestado A, Grassin-Delyle S, Guitard F, Naline E, Faisy C, Israël-Biet D, Sage E, Bellamy JF, Tenor H, Devillier P. Roflumilast inhibits the release of chemokines and TNF-α from human lung macrophages stimulated with lipopolysaccharide British Journal of Pharmacology. 165: 1877-1890. PMID 21913898 DOI: 10.1111/j.1476-5381.2011.01667.x  0.07
2009 Kzhyshkowska J, Gratchev A, Krusell L, Mamidi S, Riabov V, Zhang J, Workman G, Sage EH, Goerdt S. Stabilin-1—Multifunctional receptor linking endocytosis and secretion in macrophages Cytokine. 48: 34-35. DOI: 10.1016/j.cyto.2009.07.333  0.068
2014 Khalifé-Hocquemiller T, Sage E, Dorfmuller P, Mussot S, Le Houérou D, Eddahibi S, Fadel E. Exogenous surfactant attenuates lung injury from gastric-acid aspiration during ex vivo reconditioning in pigs Transplantation. 97: 413-418. PMID 24445923 DOI: 10.1097/01.TP.0000441320.10787.c5  0.063
2008 Marchin RM, Sage EL, Ward JK. Population-level variation of Fraxinus americana (white ash) is influenced by precipitation differences across the native range. Tree Physiology. 28: 151-9. PMID 17938124 DOI: 10.1093/Treephys/28.1.151  0.06
2008 Agrawala PK, Eschenbrenner A, Du Penhoat MAH, Boissiere A, Politis MF, Touati A, Sage E, Chetioui A. Induction and repairability of DNA damage caused by ultrasoft X-rays: Role of core events International Journal of Radiation Biology. 84: 1093-1103. PMID 19061134 DOI: 10.1080/09553000802478083  0.058
2016 Douki T, Sage E. Dewar valence isomers, the third type of environmentally relevant DNA photoproducts induced by solar radiation Photochemical and Photobiological Sciences. 15: 24-30. DOI: 10.1039/c5pp00382b  0.057
2016 Roux A, Bendib Le Lan I, Holifanjaniaina S, Thomas KA, Hamid AM, Picard C, Grenet D, De Miranda S, Douvry B, Beaumont-Azuar L, Sage E, Devaquet J, Cuquemelle E, Le Guen M, Spreafico R, et al. Antibody-Mediated Rejection in Lung Transplantation: Clinical Outcomes and Donor-Specific Antibody Characteristics. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. PMID 26845386 DOI: 10.1111/ajt.13589  0.054
2011 Faisy C, Pinto FM, Le Guen M, Naline E, Delyle SG, Sage E, Candenas ML, Devillier P. Airway response to acute mechanical stress in a human bronchial model of stretch Critical Care. 15. PMID 21914176 DOI: 10.1186/cc10443  0.051
2010 Sage EK, Noursadeghi M, Evans HE, Parker SJ, Copas AJ, Edwards SG, Miller RF. Prognostic value of C-reactive protein in HIV-infected patients with Pneumocystis jirovecii pneumonia. International Journal of Std & Aids. 21: 288-92. PMID 20378904 DOI: 10.1258/ijsa.2010.009551  0.049
2010 Mercier O, Sage E, Izziki M, Humbert M, Dartevelle P, Eddahibi S, Fadel E. Endothelin A receptor blockade improves regression of flow-induced pulmonary vasculopathy in piglets Journal of Thoracic and Cardiovascular Surgery. 140: 677-683. PMID 20723731 DOI: 10.1016/j.jtcvs.2010.01.004  0.048
2012 Sage E, Mercier O, Herve P, Tu L, Dartevelle P, Eddahibi S, Fadel E. Right lung ischemia induces contralateral pulmonary vasculopathy in an animal model Journal of Thoracic and Cardiovascular Surgery. 143: 967-973. PMID 22284626 DOI: 10.1016/j.jtcvs.2011.12.052  0.045
2013 Trebbia G, Sage E, Fadel E, Sakka SG, Cerf C. Ex vivo assessment of extravascular lung water with transpumonary thermodilution Journal of Heart and Lung Transplantation. 32: 840-842. PMID 23790251 DOI: 10.1016/j.healun.2013.05.006  0.044
2015 Roux A, Beaumont-Azuar L, Hamid AM, De Miranda S, Grenet D, Briend G, Bonnette P, Puyo P, Parquin F, Devaquet J, Trebbia G, Cuquemelle E, Douvry B, Picard C, Le Guen M, ... ... Sage E, et al. High Emergency Lung Transplantation: dramatic decrease of waiting list death rate without relevant higher post-transplant mortality. Transplant International : Official Journal of the European Society For Organ Transplantation. PMID 25959679 DOI: 10.1111/tri.12604  0.041
2012 Felten ML, Michel-Cherqui M, Sage E, Fischler M. Transesophageal and contact ultrasound echographic assessments of pulmonary vessels in bilateral lung transplantation Annals of Thoracic Surgery. 93: 1094-1100. PMID 22387146 DOI: 10.1016/j.athoracsur.2012.01.070  0.04
2013 Kalber TL, Campbell-Washburn AE, Siow BM, Sage E, Price AN, Ordidge KL, Walker-Samuel S, Janes SM, Lythgoe MF. Primed Infusion with Delayed Equilibrium of Gd.DTPA for Enhanced Imaging of Small Pulmonary Metastases Plos One. 8. PMID 23382996 DOI: 10.1371/journal.pone.0054903  0.038
2010 Pagès ON, Puyo P, Sage E, Chapelier A. Giant Pulmonary Arteriovenous Fistula Annals of Thoracic Surgery. 89: 2042. PMID 20494086 DOI: 10.1016/j.athoracsur.2009.08.080  0.035
2006 Fadel E, Wijtenburg E, Michel R, Mazoit JX, Bernatchez R, Decante B, Sage E, Mazmanian M, Hervé P. Regression of the systemic vasculature to the lung after removal of pulmonary artery obstruction American Journal of Respiratory and Critical Care Medicine. 173: 345-349. PMID 16239625 DOI: 10.1164/rccm.200506-894OC  0.034
2013 Buenestado A, Grassin-Delyle S, Guitard F, Naline E, Faisy C, Israël-Biet D, Sage E, Bellamy JF, Tenor H, Devillier P. Response to commentary: 'If roflumilast inhibits the innate immunity in the stable patient, what about infection?' Clinical Respiratory Journal. 7: e20-e21. PMID 23763715 DOI: 10.1111/crj.12019  0.033
2014 Sage E, Mussot S, Trebbia G, Puyo P, Stern M, Dartevelle P, Chapelier A, Fischler M. Lung transplantation from initially rejected donors after ex vivo lung reconditioning: the French experience. European Journal of Cardio-Thoracic Surgery : Official Journal of the European Association For Cardio-Thoracic Surgery. 46: 794-9. PMID 25061219 DOI: 10.1093/ejcts/ezu245  0.032
2016 Sansa M, Sage E, Bullard EC, Gély M, Alava T, Colinet E, Naik AK, Villanueva LG, Duraffourg L, Roukes ML, Jourdan G, Hentz S. Frequency fluctuations in silicon nanoresonators. Nature Nanotechnology. PMID 26925826 DOI: 10.1038/Nnano.2016.19  0.032
2007 Eschenbrenner A, Penhoat MAHD, Boissiere A, Eot-Houllier G, Abel F, Politis MF, Touati A, Sage E, Chetioui A. Strand breaks induced in plasmid DNA by ultrasoft X-rays: Influence of hydration and packing International Journal of Radiation Biology. 83: 687-697. PMID 17729163 DOI: 10.1080/09553000701584106  0.029
2009 Mercier O, Sage E, de Perrot M, Tu L, Marcos E, Decante B, Baudet B, Hervé P, Dartevelle P, Eddahibi S, Fadel E. Regression of flow-induced pulmonary arterial vasculopathy after flow correction in piglets Journal of Thoracic and Cardiovascular Surgery. 137: 1538-1546. PMID 19464477 DOI: 10.1016/j.jtcvs.2008.07.069  0.028
2016 Dumans-Nizard V, Guezennec J, Parquin F, Puyo P, Sage E, Abdat R, Vaillant V, Chapelier A, Dreyfus JF, Fischler M, Le Guen M. Feasibility and results of a fast-track protocol in thoracic surgery Minerva Anestesiologica. 82: 15-21.  0.026
2014 Orsini B, Sage E, Olland A, Cochet E, Tabutin M, Thumerel M, Charot F, Chapelier A, Massard G, Brichon PY, Tronc F, Jougon J, Dahan M, D'Journo XB, Reynaud-Gaubert M, et al. High-emergency waiting list for lung transplantation: early results of a nation-based study. European Journal of Cardio-Thoracic Surgery : Official Journal of the European Association For Cardio-Thoracic Surgery. 46: e41-7; discussion e4. PMID 24994754 DOI: 10.1093/ejcts/ezu259  0.026
2012 Sage E, Tyrrell R. Introduction to the themed issue on the biology of UVA Photochemical and Photobiological Sciences. 11: 28-29. PMID 22159168 DOI: 10.1039/c1pp90041b  0.024
2013 Markovitsi D, Sage E, Lewis FD, Davies J. Interaction of UV radiation with DNA. Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society For Photobiology. 12: 1256-8. PMID 23873394 DOI: 10.1039/C3Pp90021E  0.023
2015 Picard C, Boisseau M, De Miranda S, Hamid A, Grenet D, Parquin F, Sage E, Stern M, Roux A. [The management of lung transplantation candidates. A case series]. Revue Des Maladies Respiratoires. 32: 1-7. PMID 25618198 DOI: 10.1016/j.rmr.2014.02.007  0.021
2011 Messika J, Parquin F, Puyo P, Sage E, Bonnette P, Rivaud E, Catherinot E, Couderc LJ, Chapelier A. Lung surgery in haematological patients: Useful? Hazardous? | Chirurgie pulmonaire chez le malade d'hématologie: pourquoi? Pour qui? Revue De Pneumologie Clinique. 67: 220-225. PMID 21920281 DOI: 10.1016/j.pneumo.2011.06.002  0.02
2011 Pouydebasque A, Bolis S, Bridoux C, Jacquet F, Moreau S, Sage E, Saint-Patrice D, Bouvier C, Kopp C, Sillon N, Fanget S, Vigier-Blanc E. Process optimization and performance analysis of an electrostatically actuated varifocal liquid lens 2011 16th International Solid-State Sensors, Actuators and Microsystems Conference, Transducers'11. 578-581. DOI: 10.1109/TRANSDUCERS.2011.5969719  0.02
2009 Mercier O, Fadel E, De Perrot M, Sage E, Mussot S, Dartevelle P. Surgical treatment of celiac artery aneurysm associated with median arcuate ligament Journal of Cardiovascular Surgery. 50: 391-394. PMID 18948876  0.02
2004 Bardy P, Sage E, Norman J, Chunilal S, Dart G, Pittman K, Patterson K, Price T, Colbeck M, Milliken L, Luke C, Roder D. Reasons for lower survival from non-Hodgkin's lymphoma among older patients. Asian Pacific Journal of Cancer Prevention : Apjcp. 5: 301-7. PMID 15373711  0.02
2013 Perenon R, Sage E, Mohammad-Djafari A, Duraffourg L, Hentz S, Brenac A, Morel R, Grangeat P. Bayesian inversion of multi-mode NEMS mass spectrometry signal European Signal Processing Conference 0.017
2010 Mordant P, Bonnette P, Puyo P, Sage E, Grenet D, Stern M, Fischler M, Chapelier A. Advances in lung transplantation for cystic fibrosis that may improve outcome European Journal of Cardio-Thoracic Surgery. 38: 637-643. PMID 20418108 DOI: 10.1016/j.ejcts.2010.03.026  0.016
2015 Graindorge D, Martineau S, Machon C, Arnoux P, Guitton J, Francesconi S, Frochot C, Sage E, Girard PM. Singlet oxygen-mediated oxidation during UVA radiation alters the dynamic of genomic DNA replication Plos One. 10. DOI: 10.1371/journal.pone.0140645  0.015
2010 Carloni A, Sage E, Roudie J, Balzarotti R, Maître S, Sbai-Idrissi M, Smadja C. Right colonic diverticulitis: An uncommon disease in western countries Acta Chirurgica Belgica. 110: 57-59. PMID 20306911  0.013
2013 Pérenon R, Mohammad-Djafari A, Sage E, Duraffourg L, Hentz S, Brenac A, Morel R, Grangeat P. MCMC-based inversion algorithm dedicated to NEMS mass Spectrometry Aip Conference Proceedings. 1553: 46-53. DOI: 10.1063/1.4819982  0.013
2016 Sage EK, Schmid TE, Sedelmayr M, Gehrmann M, Geinitz H, Duma MN, Combs SE, Multhoff G. Comparative analysis of the effects of radiotherapy versus radiotherapy after adjuvant chemotherapy on the composition of lymphocyte subpopulations in breast cancer patients Radiotherapy and Oncology. 118: 176-180. DOI: 10.1016/j.radonc.2015.11.016  0.011
2016 Trotta M, Rhodes LE, Sage E. Shine on you crazy books: The Comprehensive Series in Photochemical & Photobiological Sciences Photochemical and Photobiological Sciences. 15: 8-9. DOI: 10.1039/c5pp90043c  0.01
2015 Sage E, Brenac A, Alava T, Morel R, Dupré C, Hanay MS, Roukes ML, Duraffourg L, Masselon C, Hentz S. Neutral particle mass spectrometry with nanomechanical systems Nature Communications. 6. DOI: 10.1038/ncomms7482  0.01
2015 Summerer I, Unger K, Braselmann H, Schuettrumpf L, Maihoefer C, Baumeister P, Kirchner T, Niyazi M, Sage E, Specht HM, Multhoff G, Moertl S, Belka C, Zitzelsberger H. Circulating microRNAs as prognostic therapy biomarkers in head and neck cancer patients British Journal of Cancer. 113: 76-82. DOI: 10.1038/bjc.2015.111  0.01
2014 Mitilian D, Sage E, Puyo P, Bonnette P, Parquin F, Stern M, Fischler M, Chapelier A. Techniques and results of lobar lung transplantations. European Journal of Cardio-Thoracic Surgery : Official Journal of the European Association For Cardio-Thoracic Surgery. 45: 365-9; discussion 36. PMID 23900745 DOI: 10.1093/ejcts/ezt353  0.01
2013 Mitilian D, Gonin F, Sage E, Beurtheret S. From relapsing polychondritis to extracorporeal membrane oxygenation Journal of Thoracic and Cardiovascular Surgery. 146: e49-e51. PMID 23993319 DOI: 10.1016/j.jtcvs.2013.07.016  0.01
2013 Lafarge M, Mordant P, Thabut G, Brouchet L, Falcoz PE, Haloun A, Le Pimpec-Barthes F, Maury JM, Reynaud-Gaubert M, Saint-Raymond C, Sage E, Stern M, Thomas P, Castier Y, Dorent R, et al. Experience of extracorporeal membrane oxygenation as a bridge to lung transplantation in France. The Journal of Heart and Lung Transplantation : the Official Publication of the International Society For Heart Transplantation. 32: 905-13. PMID 23953818 DOI: 10.1016/j.healun.2013.06.009  0.01
2013 Sage E, Martin O, Dupre C, Ernst T, Billiot G, Duraffourg L, Colinet E, Hentz S. Frequency-addressed NEMS arrays for mass and gas sensing applications 2013 Transducers and Eurosensors Xxvii: the 17th International Conference On Solid-State Sensors, Actuators and Microsystems, Transducers and Eurosensors 2013. 665-668. DOI: 10.1109/Transducers.2013.6626854  0.01
2013 Martin O, Colinet E, Sage E, Dupré C, Villard P, Hentz S, Duraffourg L, Ernst T. Impact of process variability on a frequency-addressed NEMS array sensor used for gravimetric detection European Solid-State Device Research Conference. 65-68. DOI: 10.1109/ESSDERC.2013.6818820  0.01
2012 Sage E. [ECMO in lung transplantation]. | ECMO et transplantation pulmonaire. Annales FrançAises D'AnesthèSie Et De RèAnimation. 31: S5-7. PMID 22721522  0.01
2012 Le Guen M, Trebbia G, Sage E, Cerf C, Fischler M. Intraoperative cerebral air embolism during lung transplantation: Treatment with early hyperbaric oxygen therapy Journal of Cardiothoracic and Vascular Anesthesia. 26: 1077-1079. PMID 21924628 DOI: 10.1053/j.jvca.2011.07.020  0.01
2012 Ollier E, Dupre C, Arndt G, Arcamone J, Vizioz C, Duraffourg L, Sage E, Koumela A, Hentz S, Cibrario G, Meininger P, Benotmane K, Marcoux C, Rozeau O, Billiot G, et al. Ultra-scaled high-frequency single-crystal Si NEMS resonators and their front-end co-integration with CMOS for high sensitivity applications Proceedings of the Ieee International Conference On Micro Electro Mechanical Systems (Mems). 1368-1371. DOI: 10.1109/MEMSYS.2012.6170421  0.01
2012 Sousa JS, Girard PM, Sage E, Ravanat JL, Puech V. DNA Oxidation by reactive oxygen species produced by atmospheric pressure microplasmas Nato Science For Peace and Security Series a: Chemistry and Biology. 107-119. DOI: 10.1007/978-94-007-2852-3_9  0.01
2011 Pouydebasque A, Bridoux C, Jacquet F, Moreau S, Sage E, Saint-Patrice D, Bouvier C, Kopp C, Marchand G, Bolis S, Sillon N, Vigier-Blanc E. Varifocal liquid lenses with integrated actuator, high focusing power and low operating voltage fabricated on 200 mm wafers Sensors and Actuators, a: Physical. 172: 280-286. DOI: 10.1016/j.sna.2011.05.005  0.01
2011 Douki T, Mouret S, Sage E, Béani JC, Warrick E, Bernerd F, Sarasin A, Magnaldo T. When the UV attacks the genome | Ouand les UV s' attaquent au génome Biofutur. 42-46.  0.01
2010 Michel-Cherqui M, Felten ML, Liu N, Sage E, Devaquet J, Grenet D, Fischler M. Management of takotsubo cardiomyopathy in a lung transplant recipient Transplantation. 90: 692-694. PMID 20847635 DOI: 10.1097/TP.0b013e3181ebf76a  0.01
2009 Fisk M, Sage EK, Edwards SG, Cartledge JD, Miller RF. Outcome from treatment of Pneumocystis jirovecii pneumonia with co-trimoxazole. International Journal of Std & Aids. 20: 652-3. PMID 19710343 DOI: 10.1258/ijsa.2009.008470  0.01
2009 Girard PM, Sage E. Letter to the Editor Dna Repair. 8: 4-5. DOI: 10.1016/j.dnarep.2008.10.003  0.01
2004 Tubiana M, Rouësse J, Averbeck D, Basset-Seguin N, Bernerd F, Cesarini JP, Corbé C, Demenais F, Dubertret L, Grob JJ, Masse R, Monier R, Morlière P, Moustacchi E, Sancho-Garnier H, ... Sage E, et al. Sun and health | Soleil et santé Bulletin De L'Academie Nationale De Medecine. 188: 843-849.  0.01
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