Alessandro Boezio - Publications

Affiliations: 
2003-2005 Harvard University, Cambridge, MA, United States 

30 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Schenkel LB, Olivieri PR, Boezio AA, Deak HL, Emkey R, Graceffa RF, Gunaydin H, Guzman-Perez A, Lee JH, Teffera Y, Wang W, Youngblood BD, Yu VL, Zhang M, Gavva NR, et al. Optimization of a Novel Quinazolinone-Based Series of Transient Receptor Potential A1 (TRPA1) Antagonists Demonstrating Potent in Vivo Activity. Journal of Medicinal Chemistry. PMID 26942860 DOI: 10.1021/acs.jmedchem.6b00039  0.76
2016 Boezio AA, Copeland KW, Rex K, Brian K Albrecht BK, Bauer D, Bellon SF, Bode C, Broome MA, Choquette D, Coxon A, Dussault I, Hirai S, Lewis RT, Lin MJ, Lohman Suchomel J, et al. Discovery of (R)-6-(1-(8-fluoro-6-(1-methyl-1H-pyrazol-4-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl)ethyl)-3-(2-methoxyethoxy)-1,6-naphthyridin-5(6H)-one (AMG 337), a Potent and Selective Inhibitor of MET with High Unbound Target Coverage and Robust In Vivo Antitumor Activity. Journal of Medicinal Chemistry. PMID 26812066 DOI: 10.1021/acs.jmedchem.5b01716  0.76
2015 Chen S, Graceffa RF, Boezio AA. Direct, Regioselective N-Alkylation of 1,3-Azoles. Organic Letters. PMID 26671035 DOI: 10.1021/acs.orglett.5b02994  0.76
2015 Peterson EA, Teffera Y, Albrecht BK, Bauer D, Bellon SF, Boezio A, Boezio C, Broome MA, Choquette D, Copeland KW, Dussault I, Lewis R, Lin MH, Lohman J, Liu J, et al. Discovery of potent and selective 8-fluorotriazolopyridine c-Met inhibitors. Journal of Medicinal Chemistry. 58: 2417-30. PMID 25699405 DOI: 10.1021/jm501913a  0.76
2014 Copeland KW, Boezio AA, Cheung E, Lee J, Olivieri P, Schenkel LB, Wan Q, Wang W, Wells MC, Youngblood B, Gavva NR, Lehto SG, Geuns-Meyer S. Development of novel azabenzofuran TRPA1 antagonists as in vivo tools. Bioorganic & Medicinal Chemistry Letters. 24: 3464-8. PMID 24953819 DOI: 10.1016/j.bmcl.2014.05.069  0.76
2012 Peterson EA, Boezio AA, Andrews PS, Boezio CM, Bush TL, Cheng AC, Choquette D, Coats JR, Colletti AE, Copeland KW, DuPont M, Graceffa R, Grubinska B, Kim JL, Lewis RT, et al. Discovery and optimization of potent and selective imidazopyridine and imidazopyridazine mTOR inhibitors. Bioorganic & Medicinal Chemistry Letters. 22: 4967-74. PMID 22765895 DOI: 10.1016/j.bmcl.2012.06.033  0.76
2012 Bode CM, Boezio AA, Albrecht BK, Bellon SF, Berry L, Broome MA, Choquette D, Dussault I, Lewis RT, Lin MH, Rex K, Whittington DA, Yang Y, Harmange JC. Discovery and optimization of a potent and selective triazolopyridinone series of c-Met inhibitors. Bioorganic & Medicinal Chemistry Letters. 22: 4089-93. PMID 22595176 DOI: 10.1016/j.bmcl.2012.04.072  0.76
2012 Liu L, Norman MH, Lee M, Xi N, Siegmund A, Boezio AA, Booker S, Choquette D, D'Angelo ND, Germain J, Yang K, Yang Y, Zhang Y, Bellon SF, Whittington DA, et al. Structure-based design of novel class II c-Met inhibitors: 2. SAR and kinase selectivity profiles of the pyrazolone series. Journal of Medicinal Chemistry. 55: 1868-97. PMID 22320327 DOI: 10.1021/jm201331s  0.76
2011 Peterson EA, Andrews PS, Be X, Boezio AA, Bush TL, Cheng AC, Coats JR, Colletti AE, Copeland KW, DuPont M, Graceffa R, Grubinska B, Harmange JC, Kim JL, Mullady EL, et al. Discovery of triazine-benzimidazoles as selective inhibitors of mTOR. Bioorganic & Medicinal Chemistry Letters. 21: 2064-70. PMID 21376583 DOI: 10.1016/j.bmcl.2011.02.007  0.76
2010 Gao B, Hierl M, Clarkin K, Juan T, Nguyen H, Valk Mv, Deng H, Guo W, Lehto SG, Matson D, McDermott JS, Knop J, Gaida K, Cao L, Waldon D, ... ... Boezio AA, et al. Pharmacological effects of nonselective and subtype-selective nicotinic acetylcholine receptor agonists in animal models of persistent pain. Pain. 149: 33-49. PMID 20167427 DOI: 10.1016/j.pain.2010.01.007  0.76
2010 Boezio AA, Berry L, Albrecht BK, Bauer D, Bellon SF, Bode C, Chen A, Choquette D, Dussault I, Fang M, Hirai S, Kaplan-Lefko P, Larrow JF, Lin MHJ, Lohman J, et al. Corrigendum to "Discovery and optimization of potent and selective triazolopyridazine series of c-Met inhibitors" [Bioorg. Med. Chem. Lett. 19 (2009) 6307] (DOI:10.1016/j.bmcl.2009.09.096) Bioorganic and Medicinal Chemistry Letters. 20: 773. DOI: 10.1016/j.bmcl.2009.11.095  0.76
2009 Boezio AA, Berry L, Albrecht BK, Bauer D, Bellon SF, Bode C, Chen A, Choquette D, Dussault I, Fang M, Hirai S, Kaplan-Lefko P, Larrow JF, Lin MH, Lohman J, et al. Discovery and optimization of potent and selective triazolopyridazine series of c-Met inhibitors. Bioorganic & Medicinal Chemistry Letters. 19: 6307-12. PMID 19819693 DOI: 10.1016/j.bmcl.2009.09.096  0.76
2009 Springer SK, Woodin KS, Berry V, Boezio AA, Cao L, Clarkin K, Harmange JC, Hierl M, Knop J, Malmberg AB, McDermott JS, Nguyen HQ, Waldon D, Albrecht BK, McDonough SI. Corrigendum to "synthesis and activity of substituted carbamates as potentiators of the α4β2 nicotinic acetylcholine receptor" [Bioorg. Med. Chem. Lett. 18 (2008) 5643-5647] (DOI:10.1016/j.bmcl.2008.08.092) Bioorganic and Medicinal Chemistry Letters. 19: 4516. DOI: 10.1016/j.bmcl.2008.08.115  0.76
2008 Teffera Y, Colletti AE, Harmange JC, Hollis LS, Albrecht BK, Boezio AA, Liu J, Zhao Z. Chemical reactivity of methoxy 4-o-aryl quinolines: identification of glutathione displacement products in vitro and in vivo. Chemical Research in Toxicology. 21: 2216-22. PMID 18837519 DOI: 10.1021/tx800307n  0.76
2008 Springer SK, Woodin KS, Berry V, Boezio AA, Cao L, Clarkin K, Harmange JC, Hierl M, Knop J, Malmberg AB, McDermott JS, Nguyen HQ, Waldon D, Albrecht BK, McDonough SI. Synthesis and activity of substituted carbamates as potentiators of the alpha4beta2 nicotinic acetylcholine receptor. Bioorganic & Medicinal Chemistry Letters. 18: 5643-7. PMID 18805006 DOI: 10.1016/j.bmcl.2008.08.092  0.76
2008 Albrecht BK, Berry V, Boezio AA, Cao L, Clarkin K, Guo W, Harmange JC, Hierl M, Huang L, Janosky B, Knop J, Malmberg A, McDermott JS, Nguyen HQ, Springer SK, et al. Discovery and optimization of substituted piperidines as potent, selective, CNS-penetrant alpha4beta2 nicotinic acetylcholine receptor potentiators. Bioorganic & Medicinal Chemistry Letters. 18: 5209-12. PMID 18789861 DOI: 10.1016/j.bmcl.2008.08.080  0.76
2008 Albrecht BK, Harmange JC, Bauer D, Berry L, Bode C, Boezio AA, Chen A, Choquette D, Dussault I, Fridrich C, Hirai S, Hoffman D, Larrow JF, Kaplan-Lefko P, Lin J, et al. Discovery and optimization of triazolopyridazines as potent and selective inhibitors of the c-Met kinase. Journal of Medicinal Chemistry. 51: 2879-82. PMID 18426196 DOI: 10.1021/jm800043g  0.76
2008 Charette AB, Côté A, Desrosiers JN, Bonnaventure I, Lindsay VNG, Lauzon C, Tannous J, Boezio AA. New methods in asymmetric catalysis based on new hemi-labile bidentate ligands Pure and Applied Chemistry. 80: 881-890. DOI: 10.1351/pac200880050881  0.76
2006 Poupon JC, Boezio AA, Charette AB. Tetraarylphosphonium salts as solubility-control groups: phosphonium-supported triphenylphosphine and azodicarboxylate reagents. Angewandte Chemie (International Ed. in English). 45: 1415-20. PMID 16425329 DOI: 10.1002/anie.200503599  0.76
2006 Desrosiers JN, Côté A, Boezio AA, Charette AB. Preparation of enantiomerically enriched (1S)-1-phenylpropan-1-amine hydrochloride by a catalytic addition of diorganozinc reagents to imines Organic Syntheses. 83: 5-17.  0.76
2006 Côté A, Desrosiers JN, Boezio AA, Charette AB. Preparation of enantiomerically pure (R,R)-BozPHOS Organic Syntheses. 83: 1-4.  0.76
2005 Boezio AA, Jarvo ER, Lawrence BM, Jacobsen EN. Efficient total syntheses of (-)-colombiasin A and (-)-elisapterosin B: application of the Cr-catalyzed asymmetric quinone Diels-Alder reaction. Angewandte Chemie (International Ed. in English). 44: 6046-50. PMID 16108082 DOI: 10.1002/anie.200502178  0.76
2005 Charette AB, Boezio AA, Côté A, Moreau E, Pytkowicz J, Desrosiers JN, Legault C. Asymmetric catalytic addition of diorganozinc reagents to imines: Scope and application Pure and Applied Chemistry. 77: 1259-1267. DOI: 10.1351/pac200577071259  0.76
2004 Côté A, Boezio AA, Charette AB. Evidence for the structure of the enantioactive ligand in the phosphine-copper-catalyzed addition of diorganozinc reagents to imines. Angewandte Chemie (International Ed. in English). 43: 6525-8. PMID 15538706 DOI: 10.1002/anie.200461920  0.76
2004 Côté A, Boezio AA, Charette AB. Catalytic asymmetric addition of diorganozinc reagents to N-phosphinoylalkylimines. Proceedings of the National Academy of Sciences of the United States of America. 101: 5405-10. PMID 15064400 DOI: 10.1073/pnas.0307096101  0.76
2003 Boezio AA, Pytkowicz J, Côté A, Charette AB. Asymmetric, catalytic synthesis of alpha-chiral amines using a novel bis(phosphine) monoxide chiral ligand. Journal of the American Chemical Society. 125: 14260-1. PMID 14624558 DOI: 10.1021/ja038291+  0.76
2003 Boezio AA, Solberghe G, Lauzon C, Charette AB. Orthoacylimines: a new class of chiral auxiliaries for nucleophilic addition of organolithium reagents to imines. The Journal of Organic Chemistry. 68: 3241-5. PMID 12688797 DOI: 10.1021/jo026571m  0.76
2003 Boezio AA, Charette AB. Catalytic enantioselective addition of dialkylzinc to N-diphenylphosphinoylimines. A practical synthesis of alpha-chiral amines. Journal of the American Chemical Society. 125: 1692-3. PMID 12580582 DOI: 10.1021/ja027673x  0.76
2001 Charette AB, Janes MK, Boezio AA. Mitsunobu reaction using tripphenylphosphine linked to non-cross-linked polystyrene Journal of Organic Chemistry. 66: 2178-2180. DOI: 10.1021/jo005727k  0.76
2000 Charette AB, Boezio AA, Janes MK. Synthesis of a triphenylphosphine reagent on non-cross-linked polystyrene support: application to the Staudinger/Aza-wittig reaction Organic Letters. 2: 3777-9. PMID 11101417  0.76
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