Fiona M Powrie - Publications

Affiliations: 
Kennedy institute of Rheumatology 

180 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Hackstein CP, Costigan D, Drexhage L, Pearson C, Bullers S, Ilott N, Akther HD, Gu Y, FitzPatrick MEB, Harrison OJ, Garner LC, Mann EH, Pandey S, Friedrich M, Provine NM, ... ... Powrie F, et al. A conserved population of MHC II-restricted, innate-like, commensal-reactive T cells in the gut of humans and mice. Nature Communications. 13: 7472. PMID 36463279 DOI: 10.1038/s41467-022-35126-3  0.455
2021 Markandey M, Bajaj A, Ilott NE, Kedia S, Travis S, Powrie F, Ahuja V. Gut microbiota: sculptors of the intestinal stem cell niche in health and inflammatory bowel disease. Gut Microbes. 13: 1990827. PMID 34747326 DOI: 10.1080/19490976.2021.1990827  0.324
2020 Mendoza JL, Fischer S, Gee MH, Lam LH, Brackenridge S, Powrie FM, Birnbaum M, McMichael AJ, Garcia KC, Gillespie GM. Interrogating the recognition landscape of a conserved HIV-specific TCR reveals distinct bacterial peptide cross-reactivity. Elife. 9. PMID 32716298 DOI: 10.7554/Elife.58128  0.393
2020 Swann JW, Koneva LA, Regan-Komito D, Sansom SN, Powrie F, Griseri T. IL-33 promotes anemia during chronic inflammation by inhibiting differentiation of erythroid progenitors Journal of Experimental Medicine. 217. PMID 32520308 DOI: 10.1084/Jem.20200164  0.405
2020 Corbin AL, Gomez-Vazquez M, Berthold DL, Attar M, Arnold IC, Powrie FM, Sansom SN, Udalova IA. IRF5 guides monocytes toward an inflammatory CD11c macrophage phenotype and promotes intestinal inflammation. Science Immunology. 5. PMID 32444476 DOI: 10.1126/Sciimmunol.Aax6085  0.416
2020 McCuaig S, Barras D, Mann EH, Friedrich M, Bullers SJ, Janney A, Garner LC, Domingo E, Koelzer VH, Delorenzi M, Tejpar S, Maughan TS, West NR, Powrie F. The interleukin 22 pathway interacts with mutant KRAS to promote poor prognosis in colon cancer Clinical Cancer Research. 26: 4313-4325. PMID 32430479 DOI: 10.1158/1078-0432.Ccr-19-1086  0.343
2020 Mukhopadhyay S, Heinz E, Porreca I, Alasoo K, Yeung A, Yang HT, Schwerd T, Forbester JL, Hale C, Agu CA, Choi YH, Rodrigues J, Capitani M, Jostins-Dean L, Thomas DC, ... ... Powrie F, et al. Loss of IL-10 signaling in macrophages limits bacterial killing driven by prostaglandin E2. The Journal of Experimental Medicine. 217. PMID 31819956 DOI: 10.1084/Jem.20180649  0.398
2019 Abeler-Dörner L, Laing AG, Lorenc A, Ushakov DS, Clare S, Speak AO, Duque-Correa MA, White JK, Ramirez-Solis R, Saran N, Bull KR, Morón B, Iwasaki J, Barton PR, Caetano S, ... ... Powrie F, et al. High-throughput phenotyping reveals expansive genetic and structural underpinnings of immune variation. Nature Immunology. PMID 31844327 DOI: 10.1038/S41590-019-0549-0  0.306
2019 Ouahed J, Spencer E, Kotlarz D, Shouval DS, Kowalik M, Peng K, Field M, Grushkin-Lerner L, Pai SY, Bousvaros A, Cho J, Argmann C, Schadt E, Mcgovern DPB, Mokry M, ... ... Powrie F, et al. Very Early Onset Inflammatory Bowel Disease: A Clinical Approach With a Focus on the Role of Genetics and Underlying Immune Deficiencies. Inflammatory Bowel Diseases. PMID 31833544 DOI: 10.1093/Ibd/Izz259  0.366
2019 Leng T, Akther HD, Hackstein CP, Powell K, King T, Friedrich M, Christoforidou Z, McCuaig S, Neyazi M, Arancibia-Cárcamo CV, Hagel J, Powrie F, Peres RS, Millar V, et al. TCR and Inflammatory Signals Tune Human MAIT Cells to Exert Specific Tissue Repair and Effector Functions. Cell Reports. 28: 3077-3091.e5. PMID 31533032 DOI: 10.1016/J.Celrep.2019.08.050  0.491
2019 Friedrich M, Pohin M, Powrie F. Cytokine Networks in the Pathophysiology of Inflammatory Bowel Disease. Immunity. 50: 992-1006. PMID 30995511 DOI: 10.1016/J.Immuni.2019.03.017  0.362
2019 Whibley N, Tucci A, Powrie F. Regulatory T cell adaptation in the intestine and skin. Nature Immunology. 20: 386-396. PMID 30890797 DOI: 10.1038/S41590-019-0351-Z  0.489
2019 Miragaia RJ, Gomes T, Chomka A, Jardine L, Riedel A, Hegazy AN, Whibley N, Tucci A, Chen X, Lindeman I, Emerton G, Krausgruber T, Shields J, Haniffa M, Powrie F, et al. Single-Cell Transcriptomics of Regulatory T Cells Reveals Trajectories of Tissue Adaptation. Immunity. PMID 30737144 DOI: 10.1016/J.Immuni.2019.01.001  0.461
2019 Schulthess J, Pandey S, Capitani M, Rue-Albrecht KC, Arnold I, Franchini F, Chomka A, Ilott NE, Johnston DGW, Pires E, McCullagh J, Sansom SN, Arancibia-Cárcamo CV, Uhlig HH, Powrie F. The Short Chain Fatty Acid Butyrate Imprints an Antimicrobial Program in Macrophages. Immunity. PMID 30683619 DOI: 10.1016/J.Immuni.2018.12.018  0.357
2019 Gu Y, Thornton E, Powrie F. Spatial Compartmentalisation of T Regulatory Cells within Intestinal Lymphoid Tissue Biology of Blood and Marrow Transplantation. 25. DOI: 10.1016/J.Bbmt.2018.12.676  0.539
2018 Dakin SG, Coles M, Sherlock JP, Powrie F, Carr AJ, Buckley CD. Pathogenic stromal cells as therapeutic targets in joint inflammation. Nature Reviews. Rheumatology. 14: 714-726. PMID 30420750 DOI: 10.1038/S41584-018-0112-7  0.384
2018 Ryzhakov G, West NR, Franchini F, Clare S, Ilott NE, Sansom SN, Bullers SJ, Pearson C, Costain A, Vaughan-Jackson A, Goettel JA, Ermann J, Horwitz BH, Buti L, Lu X, ... ... Powrie F, et al. Alpha kinase 1 controls intestinal inflammation by suppressing the IL-12/Th1 axis. Nature Communications. 9: 3797. PMID 30228258 DOI: 10.1038/S41467-018-06085-5  0.464
2018 Forbester JL, Lees EA, Goulding D, Forrest S, Yeung A, Speak A, Clare S, Coomber EL, Mukhopadhyay S, Kraiczy J, Schreiber F, Lawley TD, Hancock REW, Uhlig HH, Zilbauer M, ... Powrie F, et al. Interleukin-22 promotes phagolysosomal fusion to induce protection against Typhimurium in human epithelial cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 30217896 DOI: 10.1073/Pnas.1811866115  0.448
2018 Vivier E, Artis D, Colonna M, Diefenbach A, Di Santo JP, Eberl G, Koyasu S, Locksley RM, McKenzie ANJ, Mebius RE, Powrie F, Spits H. Innate Lymphoid Cells: 10 Years On. Cell. 174: 1054-1066. PMID 30142344 DOI: 10.1016/J.Cell.2018.07.017  0.422
2018 Stockenhuber K, Hegazy AN, West NR, Ilott NE, Stockenhuber A, Bullers SJ, Thornton EE, Arnold IC, Tucci A, Waldmann H, Ogg GS, Powrie F. Foxp3 T reg cells control psoriasiform inflammation by restraining an IFN-I-driven CD8 T cell response. The Journal of Experimental Medicine. PMID 29980582 DOI: 10.1084/Jem.20172094  0.556
2018 Uhlig HH, Powrie F. Translating Immunology into Therapeutic Concepts for Inflammatory Bowel Disease Annual Review of Immunology. 36: 755-781. PMID 29677472 DOI: 10.1146/Annurev-Immunol-042617-053055  0.433
2018 Danne C, Powrie F. Helicobacter hepaticus polysaccharide induces an anti-inflammatory response in intestinal macrophages. Microbial Cell. 5: 208-211. PMID 29611556 DOI: 10.15698/Mic2018.04.626  0.481
2017 Danne C, Ryzhakov G, Martínez-López M, Ilott NE, Franchini F, Cuskin F, Lowe EC, Bullers SJ, Arthur JSC, Powrie F. A Large Polysaccharide Produced by Helicobacter hepaticus Induces an Anti-inflammatory Gene Signature in Macrophages. Cell Host & Microbe. 22: 733-745. PMID 29241040 DOI: 10.1016/J.Chom.2017.11.002  0.443
2017 Al-Mossawi MH, Chen L, Fang H, Ridley A, de Wit J, Yager N, Hammitzsch A, Pulyakhina I, Fairfax BP, Simone D, Yi Y, Bandyopadhyay S, Doig K, Gundle R, Kendrick B, ... Powrie F, et al. Unique transcriptome signatures and GM-CSF expression in lymphocytes from patients with spondyloarthritis. Nature Communications. 8: 1510. PMID 29142230 DOI: 10.1038/S41467-017-01771-2  0.514
2017 Hegazy AN, West NR, Stubbington MJT, Wendt E, Suijker KIM, Datsi A, This S, Danne C, Campion S, Duncan SH, Owens BMJ, Uhlig HH, McMichael A, Bergthaler A, ... ... Powrie F, et al. Circulating and Tissue-resident CD4+ T Cells With Reactivity to Intestinal Microbiota Are Abundant in Healthy Individuals and Function is Altered During Inflammation. Gastroenterology. PMID 28782508 DOI: 10.1053/J.Gastro.2017.07.047  0.557
2017 West NR, Hegazy AN, Owens BMJ, Bullers SJ, Linggi B, Buonocore S, Coccia M, Görtz D, This S, Stockenhuber K, Pott J, Friedrich M, Ryzhakov G, Baribaud F, Brodmerkel C, ... ... Powrie F, et al. Erratum: Oncostatin M drives intestinal inflammation and predicts response to tumor necrosis factor-neutralizing therapy in patients with inflammatory bowel disease. Nature Medicine. 23: 788. PMID 28586341 DOI: 10.1038/Nm0617-788D  0.324
2017 Gwela A, Siddhanathi P, Chapman RW, Travis S, Powrie F, Arancibia-Cárcamo CV, Geremia A. Th1 and Innate Lymphoid Cells accumulate in Primary Sclerosing Cholangitis-associated Inflammatory Bowel Disease. Journal of Crohn's & Colitis. PMID 28383652 DOI: 10.1093/Ecco-Jcc/Jjx050  0.458
2017 Hegazy A, West N, Stubbington M, Wendt E, Suijker K, Datsi A, This S, Danne C, Campion S, Duncan S, Uhlig H, Owens B, McMichael A, Bergthaler A, Teichmann S, ... ... Powrie F, et al. Gut microbiota induce local and systemic CD4 T cell responses in healthy individuals that are altered in inflammatory bowel diseases Viszeralmedizin. DOI: 10.1055/S-0037-1604874  0.529
2017 Hegazy A, West N, Owens B, Bullers S, Linggi B, Buonocore S, Coccia M, Görtz D, This S, Stockenhuber K, Pott J, Friedrich M, Ryzhakov G, Baribaud F, Brodmerkel C, ... ... Powrie F, et al. Oncostatin M drives intestinal inflammation and predicts response to tumor necrosis factor-neutralizing therapy in patients with inflammatory bowel disease Viszeralmedizin. DOI: 10.1055/S-0037-1604794  0.323
2016 Fenton TM, Kelly A, Shuttleworth EE, Smedley C, Atakilit A, Powrie F, Campbell S, Nishimura SL, Sheppard D, Levison S, Worthington JJ, Lehtinen MJ, Travis MA. Inflammatory cues enhance TGFβ activation by distinct subsets of human intestinal dendritic cells via integrin αvβ8. Mucosal Immunology. PMID 27782111 DOI: 10.1038/Mi.2016.94  0.492
2016 Chen HH, Händel N, Ngeow J, Muller J, Hühn M, Yang HT, Heindl M, Berbers RM, Hegazy AN, Kionke J, Yehia L, Sack U, Bläser F, Rensing-Ehl A, Reifenberger J, ... ... Powrie F, et al. Immune dysregulation in patients with PTEN hamartoma tumor syndrome: Analysis of FOXP3 regulatory T cells. The Journal of Allergy and Clinical Immunology. PMID 27477328 DOI: 10.1016/J.Jaci.2016.03.059  0.363
2016 Krausgruber T, Schiering C, Adelmann K, Harrison OJ, Chomka A, Pearson C, Ahern PP, Shale M, Oukka M, Powrie F. T-bet is a key modulator of IL-23-driven pathogenic CD4(+) T cell responses in the intestine. Nature Communications. 7: 11627. PMID 27193261 DOI: 10.1038/Ncomms11627  0.509
2016 Lochmatter C, Fischer R, Charles PD, Yu Z, Powrie F, Kessler BM. Integrative Phosphoproteomics Links IL-23R Signaling with Metabolic Adaptation in Lymphocytes. Scientific Reports. 6: 24491. PMID 27080861 DOI: 10.1038/Srep24491  0.311
2016 Ilott NE, Bollrath J, Danne C, Schiering C, Shale M, Adelmann K, Krausgruber T, Heger A, Sims D, Powrie F. Defining the microbial transcriptional response to colitis through integrated host and microbiome profiling. The Isme Journal. PMID 27003245 DOI: 10.1038/Ismej.2016.40  0.32
2016 Schwerd T, Pandey S, Yang HT, Bagola K, Jameson E, Jung J, Lachmann RH, Shah N, Patel SY, Booth C, Runz H, Düker G, Bettels R, Rohrbach M, Kugathasan S, ... ... Powrie F, et al. Impaired antibacterial autophagy links granulomatous intestinal inflammation in Niemann-Pick disease type C1 and XIAP deficiency with NOD2 variants in Crohn's disease. Gut. PMID 26953272 DOI: 10.1136/Gutjnl-2015-310382  0.307
2016 Pearson C, Thornton EE, McKenzie B, Schaupp AL, Huskens N, Griseri T, West N, Tung S, Seddon BP, Uhlig HH, Powrie F. ILC3 GM-CSF production and mobilisation orchestrate acute intestinal inflammation. Elife. 5. PMID 26780670 DOI: 10.7554/Elife.10066  0.438
2016 Arnold IC, Mathisen S, Schulthess J, Danne C, Hegazy AN, Powrie F. CD11c(+) monocyte/macrophages promote chronic Helicobacter hepaticus-induced intestinal inflammation through the production of IL-23. Mucosal Immunology. 9: 352-363. PMID 26242598 DOI: 10.1038/Mi.2015.65  0.485
2015 West NR, Powrie F. Immunotherapy Not Working? Check Your Microbiota Cancer Cell. 28: 687-689. PMID 26678336 DOI: 10.1016/J.Ccell.2015.11.010  0.327
2015 de Wit J, Al-Mossawi MH, Hühn MH, Arancibia-Cárcamo CV, Doig K, Kendrick B, Gundle R, Taylor P, Mcclanahan T, Murphy E, Zhang H, Barr K, Miller JR, Hu X, Aicher TD, ... ... Powrie F, et al. RORγt inhibitors suppress TH17 responses in inflammatory arthritis and inflammatory bowel disease. The Journal of Allergy and Clinical Immunology. PMID 26611672 DOI: 10.1016/J.Jaci.2015.09.048  0.364
2015 West NR, Mccuaig S, Franchini F, Powrie F. Emerging cytokine networks in colorectal cancer Nature Reviews Immunology. 15: 615-629. PMID 26358393 DOI: 10.1038/Nri3896  0.338
2015 Hegazy AN, Powrie F. Microbiota RORgulates intestinal suppressor T cells Science. 349: 929-930. PMID 26315421 DOI: 10.1126/Science.Aad0865  0.519
2015 Alasoo K, Martinez FO, Hale C, Gordon S, Powrie F, Dougan G, Mukhopadhyay S, Gaffney DJ. Transcriptional profiling of macrophages derived from monocytes and iPS cells identifies a conserved response to LPS and novel alternative transcription. Scientific Reports. 5: 12524. PMID 26224331 DOI: 10.1038/Srep12524  0.31
2015 Fergusson JR, Hühn MH, Swadling L, Walker LJ, Kurioka A, Llibre A, Bertoletti A, Holländer G, Newell EW, Davis MM, Sverremark-Ekström E, Powrie F, Capone S, Folgori A, Barnes E, et al. CD161(int)CD8+ T cells: a novel population of highly functional, memory CD8+ T cells enriched within the gut. Mucosal Immunology. PMID 26220166 DOI: 10.1038/Mi.2015.69  0.515
2015 Griseri T, Arnold IC, Pearson C, Krausgruber T, Schiering C, Franchini F, Schulthess J, McKenzie BS, Crocker PR, Powrie F. Granulocyte Macrophage Colony-Stimulating Factor-Activated Eosinophils Promote Interleukin-23 Driven Chronic Colitis. Immunity. 43: 187-99. PMID 26200014 DOI: 10.1016/J.Immuni.2015.07.008  0.462
2015 Hale C, Yeung A, Goulding D, Pickard D, Alasoo K, Powrie F, Dougan G, Mukhopadhyay S. Induced pluripotent stem cell derived macrophages as a cellular system to study salmonella and other pathogens. Plos One. 10: e0124307. PMID 25946027 DOI: 10.1371/Journal.Pone.0124307  0.379
2015 Arnold IC, Hutchings C, Kondova I, Hey A, Powrie F, Beverley P, Tchilian E. Helicobacter hepaticus infection in BALB/c mice abolishes subunit-vaccine-induced protection against M. tuberculosis Vaccine. 33: 1808-1814. PMID 25748336 DOI: 10.1016/J.Vaccine.2015.02.041  0.311
2015 Pearson C, Thornton EE, McKenzie B, Schaupp A, Huskens N, Griseri T, West N, Tung S, Seddon BP, Uhlig HH, Powrie F. Author response: ILC3 GM-CSF production and mobilisation orchestrate acute intestinal inflammation Elife. DOI: 10.7554/Elife.10066.021  0.317
2014 Schiering C, Krausgruber T, Chomka A, Fröhlich A, Adelmann K, Wohlfert EA, Pott J, Griseri T, Bollrath J, Hegazy AN, Harrison OJ, Owens BM, Löhning M, Belkaid Y, Fallon PG, ... Powrie F, et al. The alarmin IL-33 promotes regulatory T-cell function in the intestine. Nature. 513: 564-8. PMID 25043027 DOI: 10.1038/Nature13577  0.533
2014 Steward-Tharp SM, Laurence A, Kanno Y, Kotlyar A, Villarino AV, Sciume G, Kuchen S, Resch W, Wohlfert EA, Jiang K, Hirahara K, Vahedi G, Sun HW, Feigenbaum L, Milner JD, ... ... Powrie F, et al. A mouse model of HIES reveals pro- and anti-inflammatory functions of STAT3. Blood. 123: 2978-87. PMID 24632714 DOI: 10.1182/Blood-2013-09-523167  0.438
2014 Al-Mossawi MH, Wit JD, Huhn M, Ridley A, Bunting H, Arancibia C, Powrie F, Bowness P. In-Vitro Supression Of Th17 Responses In Inflammatory Arthritis Patients Using Small Molecule Ror-Gamma-T Inhibitors Annals of the Rheumatic Diseases. 73: 357-357. DOI: 10.1136/Annrheumdis-2014-Eular.1110  0.463
2014 Hegazy AN, Datsi A, Uhlig H, Powrie F. P036 Polyfunctionality of human gut-homing CD4 T cells Journal of Crohn's and Colitis. 8. DOI: 10.1016/S1873-9946(14)60158-6  0.481
2014 Geremia A, Arancibia C, Gwela A, Chapman RW, Travis SPL, Powrie F. OP001 Innate lymphoid cells accumulate in IBD Journal of Crohn's and Colitis. 8. DOI: 10.1016/S1873-9946(14)60002-7  0.467
2013 Bollrath J, Powrie FM. Controlling the frontier: regulatory T-cells and intestinal homeostasis. Seminars in Immunology. 25: 352-7. PMID 24184013 DOI: 10.1016/J.Smim.2013.09.002  0.538
2013 Bollrath J, Powrie F. Immunology. Feed your Tregs more fiber. Science. 341: 463-464. PMID 23908210 DOI: 10.1126/Science.1242674  0.469
2013 Harrison OJ, Powrie FM. Regulatory T cells and immune tolerance in the intestine. Cold Spring Harbor Perspectives in Biology. 5. PMID 23818502 DOI: 10.1101/Cshperspect.A018341  0.523
2013 Kirchberger S, Royston DJ, Boulard O, Thornton E, Franchini F, Szabady RL, Harrison O, Powrie F. Innate lymphoid cells sustain colon cancer through production of interleukin-22 in a mouse model. The Journal of Experimental Medicine. 210: 917-31. PMID 23589566 DOI: 10.1084/Jem.20122308  0.461
2013 Knosp CA, Schiering C, Spence S, Carroll HP, Nel HJ, Osbourn M, Jackson R, Lyubomska O, Malissen B, Ingram R, Fitzgerald DC, Powrie F, Fallon PG, Johnston JA, Kissenpfennig A. Regulation of Foxp3+ inducible regulatory T cell stability by SOCS2. Journal of Immunology (Baltimore, Md. : 1950). 190: 3235-45. PMID 23455506 DOI: 10.4049/Jimmunol.1201396  0.568
2013 Shale M, Schiering C, Powrie F. CD4+ T-cell subsets in intestinal inflammation Immunological Reviews. 252: 164-182. PMID 23405904 DOI: 10.1111/Imr.12039  0.601
2013 Spits H, Artis D, Colonna M, Diefenbach A, Di Santo JP, Eberl G, Koyasu S, Locksley RM, McKenzie AN, Mebius RE, Powrie F, Vivier E. Innate lymphoid cells--a proposal for uniform nomenclature. Nature Reviews. Immunology. 13: 145-9. PMID 23348417 DOI: 10.1038/Nri3365  0.387
2013 Beverley P, Ronan E, Lee L, Arnold I, Bolinger B, Powrie F, Tchilian E. Environmental effects on protection against Mycobacterium tuberculosis after immunization with Ad85A. Vaccine. 31: 1086-93. PMID 23262169 DOI: 10.1016/J.Vaccine.2012.12.024  0.435
2013 Cosgrove C, Ussher JE, Rauch A, Gärtner K, Kurioka A, Hühn MH, Adelmann K, Kang YH, Fergusson JR, Simmonds P, Goulder P, Hansen TH, Fox J, Günthard HF, Khanna N, ... Powrie F, et al. Early and nonreversible decrease of CD161++ /MAIT cells in HIV infection. Blood. 121: 951-61. PMID 23255555 DOI: 10.1182/Blood-2012-06-436436  0.467
2013 Barnes MJ, Griseri T, Johnson AM, Young W, Powrie F, Izcue A. CTLA-4 promotes Foxp3 induction and regulatory T cell accumulation in the intestinal lamina propria. Mucosal Immunology. 6: 324-34. PMID 22910217 DOI: 10.1038/Mi.2012.75  0.565
2013 Cosgrove C, Ussher JE, Rauch A, Gärtner K, Kurioka A, Hühn MH, Adelmann K, Kang Y, Fergusson JR, Simmonds P, Goulder P, Hansen TH, Fox J, Günthard HF, Khanna N, ... Powrie F, et al. Early and non-reversible decrease of CD161++/mucosal associated invariant T cells in HIV infection Journal of Infection. 67: 342-343. DOI: 10.1016/J.Jinf.2013.07.003  0.414
2012 Griseri T, McKenzie BS, Schiering C, Powrie F. Dysregulated Hematopoietic Stem and Progenitor Cell Activity Promotes Interleukin-23-Driven Chronic Intestinal Inflammation Immunity. 37: 1116-1129. PMID 23200826 DOI: 10.1016/J.Immuni.2012.08.025  0.488
2012 Coccia M, Harrison OJ, Schiering C, Asquith MJ, Becher B, Powrie F, Maloy KJ. IL-1β mediates chronic intestinal inflammation by promoting the accumulation of IL-17A secreting innate lymphoid cells and CD4+ Th17 cells Journal of Experimental Medicine. 209: 1595-1609. PMID 22891275 DOI: 10.1084/Jem.20111453  0.495
2012 Izcue A, Powrie F. Immunology: Malnutrition promotes rogue bacteria Nature. 487: 437-439. PMID 22836994 DOI: 10.1038/487437A  0.365
2012 Boulard O, Kirchberger S, Royston DJ, Maloy KJ, Powrie FM. Identification of a genetic locus controlling bacteria-driven colitis and associated cancer through effects on innate inflammation. The Journal of Experimental Medicine. 209: 1309-24. PMID 22734048 DOI: 10.1084/Jem.20120239  0.378
2012 Pearson C, Uhlig HH, Powrie F. Lymphoid microenvironments and innate lymphoid cells in the gut. Trends in Immunology. 33: 289-96. PMID 22578693 DOI: 10.1016/J.It.2012.04.004  0.486
2012 Powrie F. Gut reactions: immune pathways in the intestine in health and disease Embo Molecular Medicine. 4: 71-74. PMID 22278905 DOI: 10.1002/Emmm.201100197  0.462
2012 Sakaguchi S, Powrie F, Ransohoff RM. Re-establishing immunological self-tolerance in autoimmune disease Nature Medicine. 18: 54-58. PMID 22227673 DOI: 10.1038/Nm.2622  0.431
2012 Walker LJ, Kang YH, Smith MO, Tharmalingham H, Ramamurthy N, Fleming VM, Sahgal N, Leslie A, Oo Y, Geremia A, Scriba TJ, Hanekom WA, Lauer GM, Lantz O, Adams DH, ... Powrie F, et al. Human MAIT and CD8αα cells develop from a pool of type-17 precommitted CD8+ T cells. Blood. 119: 422-33. PMID 22086415 DOI: 10.1182/Blood-2011-05-353789  0.517
2011 Maloy KJ, Powrie F. Intestinal homeostasis and its breakdown in inflammatory bowel disease Nature. 474: 298-306. PMID 21677746 DOI: 10.1038/Nature10208  0.438
2011 Geremia A, Arancibia-Cárcamo CV, Fleming MPP, Rust N, Singh B, Mortensen NJ, Travis SPL, Powrie F. IL-23-responsive innate lymphoid cells are increased in inflammatory bowel disease Journal of Experimental Medicine. 208: 1127-1133. PMID 21576383 DOI: 10.1084/Jem.20101712  0.499
2011 Barnes MJ, Powrie F. Immunology. The gut's Clostridium cocktail. Science (New York, N.Y.). 331: 289-90. PMID 21252334 DOI: 10.1126/Science.1201291  0.457
2011 Powrie F. Gut reactions: Immune pathways in the intestine in health and disease Cytokine. 56: 1-1. DOI: 10.1016/J.Cyto.2011.08.004  0.338
2010 Ahern PP, Schiering C, Buonocore S, McGeachy MJ, Cua DJ, Maloy KJ, Powrie F. Interleukin-23 Drives Intestinal Inflammation through Direct Activity on T Cells Immunity. 33: 279-288. PMID 20732640 DOI: 10.1016/J.Immuni.2010.08.010  0.566
2010 Asquith M, Powrie F. An innately dangerous balancing act: intestinal homeostasis, inflammation, and colitis-associated cancer Journal of Experimental Medicine. 207: 1573-1577. PMID 20679404 DOI: 10.1084/Jem.20101330  0.459
2010 Durant L, Watford WT, Ramos HL, Laurence A, Vahedi G, Wei L, Takahashi H, Sun HW, Kanno Y, Powrie F, O'Shea JJ. Diverse targets of the transcription factor STAT3 contribute to T cell pathogenicity and homeostasis. Immunity. 32: 605-15. PMID 20493732 DOI: 10.1016/J.Immuni.2010.05.003  0.559
2010 Asquith MJ, Boulard O, Powrie F, Maloy KJ. Pathogenic and Protective Roles of MyD88 in Leukocytes and Epithelial Cells in Mouse Models of Inflammatory Bowel Disease Gastroenterology. 139: 519-529. PMID 20433840 DOI: 10.1053/J.Gastro.2010.04.045  0.479
2010 Laffont S, Siddiqui KRR, Powrie F. Intestinal inflammation abrogates the tolerogenic properties of MLN CD103+ dendritic cells. European Journal of Immunology. 40: 1877-1883. PMID 20432234 DOI: 10.1002/Eji.200939957  0.479
2010 Siddiqui KRR, Laffont S, Powrie F. E-cadherin marks a subset of inflammatory dendritic cells that promote T cell-mediated colitis. Immunity. 32: 557-567. PMID 20399121 DOI: 10.1016/J.Immuni.2010.03.017  0.55
2010 Buonocore S, Ahern PP, Uhlig HH, Ivanov II, Littman DR, Maloy KJ, Powrie F. Innate lymphoid cells drive interleukin-23-dependent innate intestinal pathology. Nature. 464: 1371-5. PMID 20393462 DOI: 10.1038/Nature08949  0.527
2010 Griseri T, Asquith M, Thompson C, Powrie F. OX40 is required for regulatory T cell–mediated control of colitis Journal of Experimental Medicine. 207: 699-709. PMID 20368580 DOI: 10.1084/Jem.20091618  0.527
2010 Powrie F. Fiona Powrie: Gut diplomacy. Interview by Amy Maxmen. Journal of Experimental Medicine. 207: 4-5. PMID 20083579 DOI: 10.1084/Jem.2071Pi  0.588
2010 Boulard O, Asquith MJ, Powrie F, Maloy KJ. TLR2-independent induction and regulation of chronic intestinal inflammation. European Journal of Immunology. 40: 516-524. PMID 19950179 DOI: 10.1002/Eji.200939669  0.449
2010 Rescigno M, Iliev ID, Belkaid Y, Hall J, Hand T, santos LD, Grainger J, Fagarasan S, Powrie F, Buonocore S, Ahern P, Maloy K, Schiering C, Artis D, Blumberg R. Mucosal immunity (SY2-3) Chairpersons: Sidonia Fagarasan, Fiona Powrie International Immunology. 22. DOI: 10.1093/Intimm/Dxq283  0.355
2010 Arancibia C, Geremia A, Myles PF, Singh B, Travis S, Powrie F. S24 Characterisation of dendritic cells in IBD Journal of Crohn's and Colitis Supplements. 4: 28. DOI: 10.1016/S1873-9954(10)70051-3  0.352
2009 Laffont S, Powrie F. Immunology: Dendritic-cell genealogy Nature. 462: 732-733. PMID 20010677 DOI: 10.1038/462732A  0.43
2009 Barnes MJ, Powrie F. Regulatory T Cells Reinforce Intestinal Homeostasis Immunity. 31: 401-411. PMID 19766083 DOI: 10.1016/J.Immuni.2009.08.011  0.605
2009 Uhlig HH, Powrie F. Mouse models of intestinal inflammation as tools to understand the pathogenesis of inflammatory bowel disease European Journal of Immunology. 39: 2021-2026. PMID 19672896 DOI: 10.1002/Eji.200939602  0.4
2009 Barnes MJ, Powrie F. Hybrid Treg cells: Steel frames and plastic exteriors Nature Immunology. 10: 563-564. PMID 19448654 DOI: 10.1038/Ni0609-563  0.503
2009 Izcue A, Coombes JL, Powrie F. Regulatory lymphocytes and intestinal inflammation. Annual Review of Immunology. 27: 313-338. PMID 19302043 DOI: 10.1146/Annurev.Immunol.021908.132657  0.551
2009 Edinger M, Powrie F, Chakraverty R. Regulatory mechanisms in graft-versus-host responses. Biology of Blood and Marrow Transplantation : Journal of the American Society For Blood and Marrow Transplantation. 15: 2-6. PMID 19147068 DOI: 10.1016/J.Bbmt.2008.10.013  0.467
2008 Ahern PP, Izcue A, Maloy KJ, Powrie F. The interleukin-23 axis in intestinal inflammation. Immunological Reviews. 226: 147-159. PMID 19161422 DOI: 10.1111/J.1600-065X.2008.00705.X  0.535
2008 Siddiqui KRR, Powrie F. CD103+ GALT DCs promote Foxp3+ regulatory T cells. Mucosal Immunology. 1. PMID 19079226 DOI: 10.1038/Mi.2008.43  0.531
2008 Jaensson E, Uronen-Hansson H, Pabst O, Eksteen B, Tian J, Coombes JL, Berg PL, Davidsson T, Powrie F, Johansson-Lindbom B, Agace WW. Small intestinal CD103+ dendritic cells display unique functional properties that are conserved between mice and humans. The Journal of Experimental Medicine. 205: 2139-49. PMID 18710932 DOI: 10.1084/Jem.20080414  0.467
2008 Coombes JL, Powrie F. Dendritic cells in intestinal immune regulation Nature Reviews Immunology. 8: 435-446. PMID 18500229 DOI: 10.1038/Nri2335  0.441
2008 Toms C, Jessup H, Thompson C, Baban D, Davies K, Powrie F. Gpr83 expression is not required for the maintenance of intestinal immune homeostasis and regulation of T-cell-dependent colitis Immunology. 125: 302-312. PMID 18479351 DOI: 10.1111/J.1365-2567.2008.02857.X  0.485
2008 Izcue A, Hue S, Buonocore S, Arancibia-Cárcamo CV, Ahern PP, Iwakura Y, Maloy KJ, Powrie F. Interleukin-23 Restrains Regulatory T Cell Activity to Drive T Cell-Dependent Colitis Immunity. 28: 559-570. PMID 18400195 DOI: 10.1016/J.Immuni.2008.02.019  0.554
2008 Izcue A, Powrie F. Special regulatory T-cell review: Regulatory T cells and the intestinal tract--patrolling the frontier. Immunology. 123: 6-10. PMID 18154611 DOI: 10.1111/J.1365-2567.2007.02778.X  0.508
2007 Willoughby JE, Costello PS, Nicolas RH, Robinson NJ, Stamp G, Powrie F, Treisman R. Raf signaling but not the ERK effector SAP-1 is required for regulatory T cell development. Journal of Immunology (Baltimore, Md. : 1950). 179: 6836-44. PMID 17982074 DOI: 10.4049/Jimmunol.179.10.6836  0.506
2007 McGovern D, Powrie F. The IL23 axis plays a key role in the pathogenesis of IBD. Gut. 56: 1333-6. PMID 17872562 DOI: 10.1136/Gut.2006.115402  0.42
2007 Sakaguchi S, Powrie F. Emerging Challenges in Regulatory T Cell Function and Biology Science. 317: 627-629. PMID 17673654 DOI: 10.1126/Science.1142331  0.55
2007 Coombes JL, Siddiqui KR, Arancibia-Cárcamo CV, Hall J, Sun CM, Belkaid Y, Powrie F. A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-beta and retinoic acid-dependent mechanism. The Journal of Experimental Medicine. 204: 1757-64. PMID 17620361 DOI: 10.1084/Jem.20070590  0.541
2007 Stepankova R, Powrie F, Kofronova O, Kozakova H, Hudcovic T, Hrncir T, Uhlig H, Read S, Rehakova Z, Benada O, Heczko P, Strus M, Bland P, Tlaskalova-Hogenova H. Segmented filamentous bacteria in a defined bacterial cocktail induce intestinal inflammation in SCID mice reconstituted with CD45RBhigh CD4+ T cells. Inflammatory Bowel Diseases. 13: 1202-11. PMID 17607724 DOI: 10.1002/Ibd.20221  0.441
2006 Cousins L, Graham M, Tooze R, Carter C, Miller JR, Powrie FM, Macpherson GG, Butcher GW. Eosinophilic bowel disease controlled by the BB rat-derived lymphopenia/Gimap5 gene. Gastroenterology. 131: 1475-85. PMID 17064701 DOI: 10.1053/J.Gastro.2006.09.023  0.383
2006 Uhlig HH, Coombes J, Mottet C, Izcue A, Thompson C, Fanger A, Tannapfel A, Fontenot JD, Ramsdell F, Powrie F. Characterization of Foxp3+CD4+CD25+ and IL-10-secreting CD4+CD25+ T cells during cure of colitis Journal of Immunology. 177: 5852-5860. PMID 17056509 DOI: 10.4049/Jimmunol.177.9.5852  0.547
2006 Banham AH, Powrie FM, Suri-Payer E. FOXP3+ regulatory T cells: Current controversies and future perspectives. European Journal of Immunology. 36: 2832-6. PMID 17051620 DOI: 10.1002/Eji.200636459  0.509
2006 Hue S, Ahern P, Buonocore S, Kullberg MC, Cua DJ, McKenzie BS, Powrie F, Maloy KJ. Interleukin-23 drives innate and T cell-mediated intestinal inflammation Journal of Experimental Medicine. 203: 2473-2483. PMID 17030949 DOI: 10.1084/Jem.20061099  0.704
2006 Kullberg MC, Jankovic D, Feng CG, Hue S, Gorelick PL, McKenzie BS, Cua DJ, Powrie F, Cheever AW, Maloy KJ, Sher A. IL-23 plays a key role in Helicobacter hepaticus-induced T cell-dependent colitis Journal of Experimental Medicine. 203: 2485-2494. PMID 17030948 DOI: 10.1084/Jem.20061082  0.698
2006 Read S, Greenwald R, Izcue A, Robinson N, Mandelbrot D, Francisco L, Sharpe AH, Powrie F. Blockade of CTLA-4 on CD4+CD25+ regulatory T cells abrogates their function in vivo. Journal of Immunology (Baltimore, Md. : 1950). 177: 4376-83. PMID 16982872 DOI: 10.4049/Jimmunol.177.7.4376  0.491
2006 Uhlig HH, McKenzie BS, Hue S, Thompson C, Joyce-Shaikh B, Stepankova R, Robinson N, Buonocore S, Tlaskalova-Hogenova H, Cua DJ, Powrie F. Differential Activity of IL-12 and IL-23 in Mucosal and Systemic Innate Immune Pathology Immunity. 25: 309-318. PMID 16919486 DOI: 10.1016/J.Immuni.2006.05.017  0.714
2006 Izcue A, Coombes JL, Powrie F. Regulatory T cells suppress systemic and mucosal immune activation to control intestinal inflammation. Immunological Reviews. 212: 256-271. PMID 16903919 DOI: 10.1111/J.0105-2896.2006.00423.X  0.555
2006 Hue S, Maloy K, McKensie B, Cua D, Powrie F. IL-23 and Not IL-12 Is Essential for the Development of IBD Inflammatory Bowel Diseases. 12. DOI: 10.1097/00054725-200604002-00059  0.339
2006 Powrie F, Maloy K, Mottet C, Uhlig H. Control of Intestinal Inflammation by Regulatory T Cells Inflammatory Bowel Diseases. 12. DOI: 10.1097/00054725-200604002-00013  0.498
2005 Maloy KJ, Powrie F. Fueling regulation: IL-2 keeps CD4+ Treg cells fit. Nature Immunology. 6: 1071-1072. PMID 16239920 DOI: 10.1038/Ni1105-1071  0.585
2005 Annacker O, Coombes JL, Malmstrom V, Uhlig HH, Bourne T, Johansson-Lindbom B, Agace WW, Parker CM, Powrie F. Essential role for CD103 in the T cell-mediated regulation of experimental colitis Journal of Experimental Medicine. 202: 1051-1061. PMID 16216886 DOI: 10.1084/Jem.20040662  0.545
2005 Tlaskalová-Hogenová H, Tucková L, Stepánková R, Hudcovic T, Palova-Jelinkova L, Kozáková H, Rossmann P, Sanchez D, Cinová J, Hrnĉír̂ T, Kverka M, Frolová L, Uhlig H, Powrie F, Bland P. Involvement of innate immunity in the development of inflammatory and autoimmune diseases Annals of the New York Academy of Sciences. 1051: 787-798. PMID 16127016 DOI: 10.1196/Annals.1361.122  0.452
2005 Uhlig HH, Powrie F. The role of mucosal T lymphocytes in regulating intestinal inflammation Springer Seminars in Immunopathology. 27: 167-180. PMID 15959782 DOI: 10.1007/S00281-005-0206-6  0.61
2005 Roncador G, Brown PJ, Maestre L, Hue S, Martínez-Torrecuadrada JL, Ling KL, Pratap S, Toms C, Fox BC, Cerundolo V, Powrie F, Banham AH. Analysis of FOXP3 protein expression in human CD4+CD25+ regulatory T cells at the single-cell level European Journal of Immunology. 35: 1681-1691. PMID 15902688 DOI: 10.1002/Eji.200526189  0.498
2005 Coombes JL, Robinson NJ, Maloy KJ, Uhlig HH, Powrie F. Regulatory T cells and intestinal homeostasis Immunological Reviews. 204: 184-194. PMID 15790359 DOI: 10.1111/J.0105-2896.2005.00250.X  0.615
2005 Fahlén L, Read S, Gorelik L, Hurst SD, Coffman RL, Flavell RA, Powrie F. T cells that cannot respond to TGF-beta escape control by CD4(+)CD25(+) regulatory T cells. The Journal of Experimental Medicine. 201: 737-46. PMID 15753207 DOI: 10.1084/Jem.20040685  0.789
2005 Maloy KJ, Antonelli LRV, Lefevre M, Powrie F. Cure of innate intestinal immune pathology by CD4+CD25+ regulatory T cells Immunology Letters. 97: 189-192. PMID 15752557 DOI: 10.1016/J.Imlet.2005.01.004  0.554
2005 Izcue A, Powrie F. Prenatal tolerance--a role for regulatory T cells? European Journal of Immunology. 35: 379-382. PMID 15682452 DOI: 10.1002/Eji.200525996  0.479
2004 Powrie F. Immune regulation in the intestine: a balancing act between effector and regulatory T cell responses. Annals of the New York Academy of Sciences. 1029: 132-141. PMID 15681752 DOI: 10.1196/Annals.1309.030  0.62
2004 Uhlig HH, Mottet C, Powrie F. Homing of intestinal immune cells Novartis Foundation Symposium. 263: 179-188. PMID 15669642 DOI: 10.1002/0470090480.Ch13  0.503
2004 Powrie F, Uhlig H. Animal models of intestinal inflammation: Clues to the pathogenesis of inflammatory bowel disease Novartis Foundation Symposium. 263: 164-174. PMID 15669641  0.424
2004 Thompson C, Powrie F. Regulatory T cells Current Opinion in Pharmacology. 4: 408-414. PMID 15251137 DOI: 10.1016/J.Coph.2004.05.001  0.573
2004 Powrie F, Uhlig H. Animal models of intestinal inflammation: clues to the pathogenesis of inflammatory bowel disease. Novartis Foundation Symposium. 263: 164-174. DOI: 10.1002/0470090480.Ch12  0.516
2003 Powrie F, Read S, Mottet C, Uhlig H, Maloy K, Bluestone. Control of immune pathology by regulatory T cells Novartis Foundation Symposium. 252: 92-105. PMID 14609214  0.52
2003 Uhlig HH, Powrie F. Dendritic cells and the intestinal bacterial flora: A role for localized mucosal immune responses Journal of Clinical Investigation. 112: 648-651. PMID 12952911 DOI: 10.1172/Jci19545  0.424
2003 Asseman C, Read S, Powrie F. Colitogenic Th1 Cells Are Present in the Antigen-Experienced T Cell Pool in Normal Mice: Control by CD4+ Regulatory T Cells and IL-10 Journal of Immunology. 171: 971-978. PMID 12847269 DOI: 10.4049/Jimmunol.171.2.971  0.598
2003 Annacker O, Asseman C, Read S, Powrie F. Interleukin-10 in the regulation of T cell-induced colitis. Journal of Autoimmunity. 20: 277-279. PMID 12791312 DOI: 10.1016/S0896-8411(03)00045-3  0.499
2003 Mottet C, Uhlig HH, Powrie F. Cutting edge: Cure of colitis by CD4+CD25+ regulatory T cells Journal of Immunology. 170: 3939-3943. PMID 12682220 DOI: 10.4049/Jimmunol.170.8.3939  0.537
2003 Powrie F, Maloy KJ. Regulating the Regulators Science. 299: 1030-1031. PMID 12586934 DOI: 10.1126/Science.1082031  0.433
2003 Maloy KJ, Salaun L, Cahill R, Dougan G, Saunders NJ, Powrie F. CD4+CD25+ T(R) cells suppress innate immune pathology through cytokine-dependent mechanisms. Journal of Experimental Medicine. 197: 111-119. PMID 12515818 DOI: 10.1084/Jem.20021345  0.568
2003 Powrie F, Read S, Mottet C, Uhlig H, Maloy K. Control of immune pathology by regulatory T cells. Novartis Foundation Symposium. 252: 92-98. DOI: 10.1002/0470871628.Ch7  0.596
2002 Jones E, Dahm-Vicker M, Simon AK, Green A, Powrie F, Cerundolo V, Gallimore A. Depletion of CD25+ regulatory cells results in suppression of melanoma growth and induction of autoreactivity in mice. Cancer Immunity. 2: 1. PMID 12747746  0.422
2002 Golgher D, Jones E, Powrie F, Elliott T, Gallimore A. Depletion of CD25+ regulatory cells uncovers immune responses to shared murine tumor rejection antigens. European Journal of Immunology. 32: 3267-75. PMID 12555672 DOI: 10.1002/1521-4141(200211)32:11<3267::Aid-Immu3267>3.0.Co;2-1  0.444
2002 Fowler S, Powrie F. CTLA-4 expression on antigen-specific cells but not IL-10 secretion is required for oral tolerance. European Journal of Immunology. 32: 2997-3006. PMID 12355454 DOI: 10.1002/1521-4141(2002010)32:10<2997::Aid-Immu2997>3.0.Co;2-D  0.526
2002 Annacker O, Powrie F. Homeostasis of intestinal immune regulation Microbes and Infection. 4: 567-574. PMID 11959513 DOI: 10.1016/S1286-4579(02)01574-5  0.551
2001 Read S, Powrie F. Induction of inflammatory bowel disease in immunodeficient mice by depletion of regulatory T cells. Current Protocols in Immunology / Edited by John E. Coligan ... [Et Al.]. Unit 15.13. PMID 18432730 DOI: 10.1002/0471142735.Im1513S30  0.518
2001 Singh B, Powrie F, Mortensen NJ. Immune therapy in inflammatory bowel disease and models of colitis. British Journal of Surgery. 88: 1558-1569. PMID 11736965 DOI: 10.1046/J.0007-1323.2001.01909.X  0.358
2001 Singh B, Read S, Asseman C, Malmström V, Mottet C, Stephens LA, Stepankova R, Tlaskalova H, Powrie F. Control of intestinal inflammation by regulatory T cells Immunological Reviews. 182: 190-200. PMID 11722634 DOI: 10.1034/J.1600-065X.2001.1820115.X  0.579
2001 Read S, Powrie F. CD4+ regulatory T cells Current Opinion in Immunology. 13: 644-649. PMID 11677084 DOI: 10.1016/S0952-7915(01)00273-4  0.575
2001 Toms C, Powrie F. Control of intestinal inflammation by regulatory T cells. Microbes and Infection. 3: 929-935. PMID 11564441 DOI: 10.1016/S1286-4579(01)01454-X  0.532
2001 Maloy KJ, Powrie F. Regulatory T cells in the control of immune pathology Nature Immunology. 2: 816-822. PMID 11526392 DOI: 10.1038/Ni0901-816  0.498
2001 Malmström V, Shipton D, Singh B, Al-Shamkhani A, Puklavec MJ, Barclay AN, Powrie F. CD134L expression on dendritic cells in the mesenteric lymph nodes drives colitis in T cell-restored SCID mice. Journal of Immunology. 166: 6972-6981. PMID 11359859 DOI: 10.4049/Jimmunol.166.11.6972  0.519
2001 Stephens LA, Mottet C, Mason D, Powrie F. Human CD4+CD25+ thymocytes and peripheral T cells have immune suppressive activity in vitro European Journal of Immunology. 31: 1247-1254. PMID 11298351 DOI: 10.1002/1521-4141(200104)31:4<1247::Aid-Immu1247>3.0.Co;2-M  0.502
2001 Suri RM, Kukutsch N, Fowler S, Powrie F, Austyn J. Immature dendritic cells induce alternative CD4(+) T-cell responses in vivo. Transplantation Proceedings. 33: 240-240. PMID 11266798 DOI: 10.1016/S0041-1345(00)01993-X  0.532
2001 Hara M, Kingsley CI, Niimi M, Read S, Turvey SE, Bushell AR, Morris PJ, Powrie F, Wood KJ. IL-10 Is Required for Regulatory T Cells to Mediate Tolerance to Alloantigens In Vivo Journal of Immunology. 166: 3789-3796. PMID 11238621 DOI: 10.4049/Jimmunol.166.6.3789  0.573
2001 Lucas AD, Chadwick N, Warren BF, Jewell DP, Gordon S, Powrie F, Greaves DR. The Transmembrane Form of the CX3CL1 Chemokine Fractalkine Is Expressed Predominantly by Epithelial Cells in Vivo American Journal of Pathology. 158: 855-866. PMID 11238035 DOI: 10.1016/S0002-9440(10)64034-5  0.37
2000 Asseman C, Fowler S, Powrie F. Control of experimental inflammatory bowel disease by regulatory T cells American Journal of Respiratory and Critical Care Medicine. 162. PMID 11029392 DOI: 10.1164/Ajrccm.162.Supplement_3.15Tac9  0.58
2000 Read S, Malmström V, Powrie F. Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25(+)CD4(+) regulatory cells that control intestinal inflammation. Journal of Experimental Medicine. 192: 295-302. PMID 10899916 DOI: 10.1084/Jem.192.2.295  0.599
1999 Fowler S, Powrie F. Control of immune pathology by IL-10-secreting regulatory T cells. Springer Seminars in Immunopathology. 21: 287-294. PMID 10666774 DOI: 10.1007/Bf00812258  0.521
1999 Asseman C, Mauze S, Leach MW, Coffman RL, Powrie F. An essential role for interleukin 10 in the function of regulatory T cells that inhibit intestinal inflammation. The Journal of Experimental Medicine. 190: 995-1004. PMID 10510089 DOI: 10.1084/Jem.190.7.995  0.721
1999 Groux H, Powrie F. Regulatory T cells and inflammatory bowel disease Immunology Today. 20: 442-445. PMID 10500290 DOI: 10.1016/S0167-5699(99)01510-8  0.562
1999 Leach MW, Davidson NJ, Fort MM, Powrie F, Rennick DM. The role of IL-10 in inflammatory bowel disease: "of mice and men". Toxicologic Pathology. 27: 123-33. PMID 10367687 DOI: 10.1177/019262339902700124  0.555
1998 Mason D, Powrie F. Control of immune pathology by regulatory T cells Current Opinion in Immunology. 10: 649-655. PMID 9914214 DOI: 10.1016/S0952-7915(98)80084-8  0.489
1998 Read S, Mauze S, Asseman C, Bean A, Coffman R, Powrie F. CD38+ CD45RB(low) CD4+ T cells: a population of T cells with immune regulatory activities in vitro. European Journal of Immunology. 28: 3435-3447. PMID 9842886 DOI: 10.1002/(Sici)1521-4141(199811)28:11<3435::Aid-Immu3435>3.0.Co;2-P  0.697
1998 Powrie F, Mauze S, Coffman RL. CD4+ T-cells in the regulation of inflammatory responses in the intestine. Research in Immunology. 148: 576-81. PMID 9588837 DOI: 10.1016/S0923-2494(98)80152-1  0.698
1998 Asseman C, Powrie F. Interleukin 10 is a growth factor for a population of regulatory T cells Gut. 42: 157-158. PMID 9536936 DOI: 10.1136/Gut.42.2.157  0.599
1997 Cahill RJ, Foltz CJ, Fox JG, Dangler CA, Powrie F, Schauer DB. Inflammatory bowel disease: an immunity-mediated condition triggered by bacterial infection with Helicobacter hepaticus. Infection and Immunity. 65: 3126-31. PMID 9234764 DOI: 10.1128/Iai.65.8.3126-3131.1997  0.539
1996 Powrie F, Carlino J, Leach MW, Mauze S, Coffman RL. A critical role for transforming growth factor-beta but not interleukin 4 in the suppression of T helper type 1-mediated colitis by CD45RB(low) CD4+ T cells. The Journal of Experimental Medicine. 183: 2669-74. PMID 8676088 DOI: 10.1084/Jem.183.6.2669  0.723
1995 Powrie F. T cells in inflammatory bowel disease: protective and pathogenic roles Immunity. 3: 171-174. PMID 7648390 DOI: 10.1016/1074-7613(95)90086-1  0.497
1994 Powrie F, Correa-Oliveira R, Mauze S, Coffman RL. Regulatory interactions between CD45RBhigh and CD45RBlow CD4+ T cells are important for the balance between protective and pathogenic cell-mediated immunity. The Journal of Experimental Medicine. 179: 589-600. PMID 7905019 DOI: 10.1084/Jem.179.2.589  0.739
1994 Powrie F, Coffman RL, Correa-Oliveira R. Transfer of CD4+ T cells to C.B-17 SCID mice: a model to study Th1 and Th2 cell differentiation and regulation in vivo. Research in Immunology. 145: 347-53. PMID 7701113 DOI: 10.1016/S0923-2494(94)80198-3  0.723
1994 Powrie F, Leach MW, Mauze S, Menon S, Caddle LB, Coffman RL. Inhibition of Th1 responses prevents inflammatory bowel disease in scid mice reconstituted with CD45RBhi CD4+ T cells. Immunity. 1: 553-62. PMID 7600284 DOI: 10.1016/1074-7613(94)90045-0  0.678
1993 Powrie F, Menon S, Coffman RL. Interleukin-4 and interleukin-10 synergize to inhibit cell-mediated immunity in vivo. European Journal of Immunology. 23: 2223-9. PMID 8370402 DOI: 10.1002/Eji.1830230926  0.614
1993 Powrie F, Coffman RL. Cytokine regulation of T-cell function: potential for therapeutic intervention. Trends in Pharmacological Sciences. 14: 164-8. PMID 8105593 DOI: 10.1016/0165-6147(93)90202-U  0.726
1993 Powrie F, Coffman RL. Cytokine regulation of T-cell function: potential for therapeutic intervention. Immunology Today. 14: 270-4. PMID 8104408 DOI: 10.1016/0167-5699(93)90044-L  0.726
1993 Powrie F, Coffman RL. Inhibition of cell-mediated immunity by IL4 and IL10. Research in Immunology. 144: 639-43. PMID 7905657 DOI: 10.1016/S0923-2494(05)80019-7  0.604
1993 Powrie F, Leach MW, Mauze S, Caddle LB, Coffman RL. Phenotypically distinct subsets of CD4+ T cells induce or protect from chronic intestinal inflammation in C. B-17 scid mice. International Immunology. 5: 1461-71. PMID 7903159 DOI: 10.1093/Intimm/5.11.1461  0.695
1991 Powrie F, Fowell D, McKnight AJ, Mason D. Lineage relationships and functions of CD4+ T-cell subsets in the rat. Research in Immunology. 142: 54-58. PMID 1711707 DOI: 10.1016/0923-2494(91)90013-9  0.472
1991 Fowell D, McKnight AJ, Powrie F, Dyke R, Mason D. Subsets of CD4+ T cells and their roles in the induction and prevention of autoimmunity. Immunological Reviews. 123: 37-64. PMID 1684782 DOI: 10.1111/J.1600-065X.1991.Tb00605.X  0.535
1990 Powrie F, Mason D. OX-22high CD4+ T cells induce wasting disease with multiple organ pathology: prevention by the OX-22low subset. Journal of Experimental Medicine. 172: 1701-1708. PMID 2258700 DOI: 10.1084/Jem.172.6.1701  0.528
1990 Powrie F, Mason D. Subsets of rat CD4+ T cells defined by their differential expression of variants of the CD45 antigen: developmental relationships and in vitro and in vivo functions. Current Topics in Microbiology and Immunology. 159: 79-96. PMID 1971782 DOI: 10.1007/978-3-642-75244-5_5  0.537
1989 Powrie F, Mason D. The MRC OX-22- CD4+ T cells that help B cells in secondary immune responses derive from naive precursors with the MRC OX-22+ CD4+ phenotype. Journal of Experimental Medicine. 169: 653-662. PMID 2784479 DOI: 10.1084/Jem.169.3.653  0.521
1989 Powrie F, Mason D. Subsets of rat CD4+ T cells express different variants of the leukocyte-common antigen: functions and developmental relationships of the subsets. Journal of Autoimmunity. 2: 25-32. PMID 2570589 DOI: 10.1016/0896-8411(89)90114-5  0.467
1988 Powrie F, Mason D. Phenotypic and functional heterogeneity of CD4+ T cells Immunology Today. 9: 274-277. PMID 2908230 DOI: 10.1016/0167-5699(88)91309-6  0.503
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