Year |
Citation |
Score |
2021 |
Chaudhry SR, Lopes J, Levin NK, Kalpage H, Tainsky MA. Germline mutations in apoptosis pathway genes in ovarian cancer; the functional role of a TP53I3 (PIG3) variant in ROS production and DNA repair. Cell Death Discovery. 7: 62. PMID 33782397 DOI: 10.1038/s41420-021-00442-y |
0.332 |
|
2019 |
Lopes JL, Chaudhry S, Lopes GS, Levin NK, Tainsky MA. FANCM, RAD1, CHEK1 and TP53I3 act as BRCA-like tumor suppressors and are mutated in hereditary ovarian cancer. Cancer Genetics. PMID 31078449 DOI: 10.1016/j.cancergen.2019.04.061 |
0.343 |
|
2016 |
Ahsan S, Ge Y, Tainsky MA. Combinatorial therapeutic targeting of BMP2 and MEK-ERK pathways in NF1-associated malignant peripheral nerve sheath tumors. Oncotarget. PMID 27494873 DOI: 10.18632/oncotarget.11036 |
0.313 |
|
2014 |
Purcell M, Kruger A, Tainsky MA. Gene expression profiling of replicative and induced senescence. Cell Cycle (Georgetown, Tex.). 13: 3927-37. PMID 25483067 DOI: 10.4161/15384101.2014.973327 |
0.616 |
|
2013 |
Sun D, Haddad R, Kraniak JM, Horne SD, Tainsky MA. RAS/MEK-independent gene expression reveals BMP2-related malignant phenotypes in the Nf1-deficient MPNST. Molecular Cancer Research : McR. 11: 616-27. PMID 23423222 DOI: 10.1158/1541-7786.Mcr-12-0593 |
0.629 |
|
2012 |
Kaplun L, Fridman AL, Chen W, Levin NK, Ahsan S, Petrucelli N, Barrick JL, Gold R, Land S, Simon MS, Morris RT, Munkarah AR, Tainsky MA. Variants in the Signaling Protein TSAd are Associated with Susceptibility to Ovarian Cancer in BRCA1/2 Negative High Risk Families. Biomarker Insights. 7: 151-7. PMID 23300341 DOI: 10.4137/Bmi.S10815 |
0.64 |
|
2012 |
Sun D, Tainsky MA, Haddad R. Oncogene Mutation Survey in MPNST Cell Lines Enhances the Dominant Role of Hyperactive Ras in NF1 Associated Pro-Survival and Malignancy. Translational Oncogenomics. 5: 1-7. PMID 22346343 DOI: 10.4137/Tog.S8830 |
0.536 |
|
2011 |
Li Q, Tainsky MA. Epigenetic silencing of IRF7 and/or IRF5 in lung cancer cells leads to increased sensitivity to oncolytic viruses. Plos One. 6: e28683. PMID 22194884 DOI: 10.1371/journal.pone.0028683 |
0.316 |
|
2011 |
Moolmuang B, Tainsky MA. CREG1 enhances p16(INK4a) -induced cellular senescence. Cell Cycle (Georgetown, Tex.). 10: 518-30. PMID 21263217 DOI: 10.4161/Cc.10.3.14756 |
0.763 |
|
2010 |
Kraniak JM, Sun D, Mattingly RR, Reiners JJ, Tainsky MA. The role of neurofibromin in N-Ras mediated AP-1 regulation in malignant peripheral nerve sheath tumors. Molecular and Cellular Biochemistry. 344: 267-76. PMID 20680410 DOI: 10.1007/S11010-010-0551-1 |
0.565 |
|
2008 |
Fridman AL, Tainsky MA. Critical pathways in cellular senescence and immortalization revealed by gene expression profiling. Oncogene. 27: 5975-87. PMID 18711403 DOI: 10.1038/onc.2008.213 |
0.734 |
|
2008 |
Li Q, Tang L, Roberts PC, Kraniak JM, Fridman AL, Kulaeva OI, Tehrani OS, Tainsky MA. Interferon regulatory factors IRF5 and IRF7 inhibit growth and induce senescence in immortal Li-Fraumeni fibroblasts. Molecular Cancer Research : McR. 6: 770-84. PMID 18505922 DOI: 10.1158/1541-7786.Mcr-07-0114 |
0.726 |
|
2007 |
Nahhas F, Dryden SC, Abrams J, Tainsky MA. Mutations in SIRT2 deacetylase which regulate enzymatic activity but not its interaction with HDAC6 and tubulin. Molecular and Cellular Biochemistry. 303: 221-30. PMID 17516032 DOI: 10.1007/S11010-007-9478-6 |
0.708 |
|
2007 |
Fridman AL, Rosati R, Li Q, Tainsky MA. Epigenetic and functional analysis of IGFBP3 and IGFBPrP1 in cellular immortalization. Biochemical and Biophysical Research Communications. 357: 785-91. PMID 17451653 DOI: 10.1016/J.Bbrc.2007.04.019 |
0.751 |
|
2007 |
Xu J, Zhou JY, Tainsky MA, Wu GS. Evidence that tumor necrosis factor-related apoptosis-inducing ligand induction by 5-Aza-2'-deoxycytidine sensitizes human breast cancer cells to adriamycin. Cancer Research. 67: 1203-11. PMID 17283156 DOI: 10.1158/0008-5472.CAN-06-2310 |
0.307 |
|
2007 |
Southwood CM, Peppi M, Dryden S, Tainsky MA, Gow A. Microtubule deacetylases, SirT2 and HDAC6, in the nervous system. Neurochemical Research. 32: 187-95. PMID 16933150 DOI: 10.1007/S11064-006-9127-6 |
0.345 |
|
2006 |
Fridman AL, Tang L, Kulaeva OI, Ye B, Li Q, Nahhas F, Roberts PC, Land SJ, Abrams J, Tainsky MA. Expression profiling identifies three pathways altered in cellular immortalization: interferon, cell cycle, and cytoskeleton. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 61: 879-89. PMID 16960018 DOI: 10.1093/Gerona/61.9.879 |
0.752 |
|
2006 |
Tang L, Roberts PC, Kraniak JM, Li Q, Tainsky MA. Stat1 expression is not sufficient to regulate the interferon signaling pathway in cellular immortalization. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 26: 14-26. PMID 16426144 DOI: 10.1089/Jir.2006.26.14 |
0.483 |
|
2006 |
Chatterjee M, Mohapatra S, Ionan A, Bawa G, Ali-Fehmi R, Wang X, Nowak J, Ye B, Nahhas FA, Lu K, Witkin SS, Fishman D, Munkarah A, Morris R, Levin NK, ... ... Tainsky MA, et al. Diagnostic markers of ovarian cancer by high-throughput antigen cloning and detection on arrays. Cancer Research. 66: 1181-90. PMID 16424057 DOI: 10.1158/0008-5472.Can-04-2962 |
0.697 |
|
2005 |
Desai V, Khatri P, Done A, Fridman A, Tainsky M, Draghici S. A novel bioinformatics technique for predicting condition-specific transcription factor binding sites Proceedings of the 2005 Ieee Symposium On Computational Intelligence in Bioinformatics and Computational Biology, Cibcb '05. 2005. |
0.302 |
|
2004 |
Dolgachev V, Farooqui MS, Kulaeva OI, Tainsky MA, Nagy B, Hanada K, Separovic D. De novo ceramide accumulation due to inhibition of its conversion to complex sphingolipids in apoptotic photosensitized cells. The Journal of Biological Chemistry. 279: 23238-49. PMID 15020599 DOI: 10.1074/jbc.M311974200 |
0.303 |
|
2003 |
Kulaeva OI, Draghici S, Tang L, Kraniak JM, Land SJ, Tainsky MA. Epigenetic silencing of multiple interferon pathway genes after cellular immortalization. Oncogene. 22: 4118-27. PMID 12821946 DOI: 10.1038/Sj.Onc.1206594 |
0.45 |
|
2003 |
Dryden SC, Nahhas FA, Nowak JE, Goustin AS, Tainsky MA. Role for human SIRT2 NAD-dependent deacetylase activity in control of mitotic exit in the cell cycle. Molecular and Cellular Biology. 23: 3173-85. PMID 12697818 DOI: 10.1128/Mcb.23.9.3173-3185.2003 |
0.743 |
|
2003 |
Draghici S, Khatri P, Shah A, Tainsky MA. Assessing the functional bias of commercial microarrays using the onto-compare database. Biotechniques. 55-61. PMID 12664686 DOI: 10.2144/Mar03Draghici |
0.333 |
|
1999 |
Kannan P, Tainsky MA. Coactivator PC4 mediates AP-2 transcriptional activity and suppresses ras-induced transformation dependent on AP-2 transcriptional interference Molecular and Cellular Biology. 19: 899-908. PMID 9858613 |
0.348 |
|
1998 |
Gollahon LS, Kraus E, Wu TA, Yim SO, Strong LC, Shay JW, Tainsky MA. Telomerase activity during spontaneous immortalization of Li-Fraumeni syndrome skin fibroblasts Oncogene. 17: 709-717. PMID 9715272 DOI: 10.1038/Sj.Onc.1201987 |
0.315 |
|
1998 |
Jean D, Gershenwald JE, Huang S, Luca M, Hudson MJ, Tainsky MA, Bar-Eli M. Loss of AP-2 results in up-regulation of MCAM/MUC18 and an increase in tumor growth and metastasis of human melanoma cells. The Journal of Biological Chemistry. 273: 16501-8. PMID 9632718 DOI: 10.1074/Jbc.273.26.16501 |
0.374 |
|
1998 |
Deyo JE, Chiao PJ, Tainsky MA. drp, a novel protein expressed at high cell density but not during growth arrest Dna and Cell Biology. 17: 437-447. PMID 9628587 DOI: 10.1089/Dna.1998.17.437 |
0.622 |
|
1998 |
Leach SD, Berger DH, Davidson BS, Curley SA, Tainsky MA. Enhanced Krev-1 expression inhibits the growth of pancreatic adenocarcinoma cells. Pancreas. 16: 491-8. PMID 9598810 |
0.371 |
|
1996 |
Liu PK, Kraus E, Wu TA, Strong LC, Tainsky MA. Analysis of genomic instability in Li-Fraumeni fibroblasts with germline p53 mutations Oncogene. 12: 2267-2278. PMID 8649766 |
0.322 |
|
1996 |
Kim SY, Berger D, Yim SO, Sacks PG, Tainsky MA. Coordinate control of growth and cytokeratin 13 expression by retinoic acid. Molecular Carcinogenesis. 16: 6-11. PMID 8634095 DOI: 10.1002/(SICI)1098-2744(199605)16:1<6::AID-MC2>3.0.CO;2-I |
0.338 |
|
1996 |
van Golen KL, Risin S, Staroselsky A, Berger D, Tainsky MA, Pathak S, Price JE. Predominance of the metastatic phenotype in hybrids formed by fusion of mouse and human melanoma clones. Clinical & Experimental Metastasis. 14: 95-106. PMID 8605733 DOI: 10.1007/BF00121206 |
0.316 |
|
1995 |
Tsutsui T, Fujino T, Kodama S, Tainsky MA, Boyd J, Barrett JC. Aflatoxin B1-induced immortalization of cultured skin fibroblasts from a patient with li-fraumeni syndrome Carcinogenesis. 16: 25-34. PMID 7834802 DOI: 10.1093/carcin/16.1.25 |
0.303 |
|
1994 |
Kannan P, Buettner R, Chiao PJ, Yim SO, Sarkiss M, Tainsky MA. N-ras oncogene causes AP-2 transcriptional self-interference, which leads to transformation. Genes & Development. 8: 1258-69. PMID 7926729 DOI: 10.1101/Gad.8.11.1258 |
0.587 |
|
1994 |
Byrne C, Tainsky M, Fuchs E. Programming gene expression in developing epidermis Development. 120: 2369-2383. PMID 7525178 |
0.322 |
|
1994 |
Dameron KM, Volpert OV, Tainsky MA, Bouck N. Control of angiogenesis in fibroblasts by p53 regulation of thrombospondin-1 Science. 265: 1582-1584. PMID 7521539 DOI: 10.1126/Science.7521539 |
0.342 |
|
1993 |
Shin DM, Chiao PJ, Sacks PG, Shin HJ, Hong WK, Hittelman WN, Tainsky MA. Activation of ribosomal protein S2 gene expression in a hamster model of chemically induced oral carcinogenesis. Carcinogenesis. 14: 163-6. PMID 8425267 DOI: 10.1093/Carcin/14.1.163 |
0.643 |
|
1993 |
Buettner R, Bauer R, Imhof A, Tainsky MA, Hofstaedter F. AP-2: a nuclear effector of malignant transformation by ras oncogene Verhandlungen Der Deutschen Gesellschaft Fur Pathologie. 77: 271-275. PMID 7511296 |
0.307 |
|
1992 |
Nicolson GL, Gallick GE, Spohn WH, Lembo TM, Tainsky MA. Transfection of activated c-H-rasEJ/pSV2neo or pSV2neo genes into rat mammary cells: Rapid stimulation of clonal diversification of spontaneous metastatic and cell-surface properties Oncogene. 7: 1127-1135. PMID 1594244 |
0.371 |
|
1992 |
Chiao PJ, Shin DM, Sacks PG, Hong WK, Tainsky MA. Elevated expression of the ribosomal protein S2 gene in human tumors. Molecular Carcinogenesis. 5: 219-31. PMID 1586449 DOI: 10.1002/Mc.2940050309 |
0.645 |
|
1992 |
Yin Y, Tainsky MA, Bischoff FZ, Strong LC, Wahl GM. Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles Cell. 70: 937-948. PMID 1525830 DOI: 10.1016/0092-8674(92)90244-7 |
0.365 |
|
1992 |
Gopas J, Ehrlich T, Cohen O, Wishniak O, Tainsky MA, Segal S, Rager-Zisman B, Isakov N. The H-ras oncogene regulates expression of 70- and 45-kDa cell-surface molecules whose expression correlates with tumor-cell immunogenicity International Journal of Cancer. 52: 329-335. PMID 1521919 DOI: 10.1002/ijc.2910520229 |
0.347 |
|
1991 |
Buettner R, Yim SO, Hong YS, Boncinelli E, Tainsky MA. Alteration of homeobox gene expression by N-ras transformation of PA-1 human teratocarcinoma cells Molecular and Cellular Biology. 11: 3573-3583. PMID 1675427 |
0.347 |
|
1990 |
Krizman DB, Giovanella BC, Tainsky MA. Susceptibility for N-ras-mediated transformation requires loss of tumor suppressor activity Somatic Cell and Molecular Genetics. 16: 15-27. PMID 2408157 DOI: 10.1007/BF01650476 |
0.318 |
|
1990 |
Chiao PJ, Bischoff FZ, Strong LC, Tainsky MA. The current state of oncogenes and cancer: Experimental approaches for analyzing oncogenetic events in human cancer Cancer and Metastasis Review. 9: 63-80. PMID 2208569 DOI: 10.1007/Bf00047589 |
0.641 |
|
1989 |
Ames RS, Fry KD, Roth JA, North SM, Tainsky MA, Nicolson GL. Analysis of Expression of Cell Surface Antigen Mr 74,000 Phosphoglycoprotein in Normal, Oncogene-transformed, and Neoplastic Rat Cell Lines Cancer Research. 49: 2312-2319. PMID 2650864 |
0.325 |
|
1989 |
Ananthaswamy HN, Price JE, Tainsky MA, Goldberg LH, Bales ES. Correlation between Ha-ras gene amplification and spontaneous metastasis in NIH 3T3 cells transfected with genomic DNA from human skin cancers. Clinical & Experimental Metastasis. 7: 301-13. PMID 2647332 DOI: 10.1007/BF01753682 |
0.336 |
|
1988 |
Tainsky MA, Krizman DB, Chiao PJ, Yim SO, Giovanella BC. PA-1, a human cell model for multistage carcinogenesis: Oncogenes and other factors Anticancer Research. 8: 899-914. PMID 3052262 |
0.34 |
|
1987 |
Olson EN, Spizz G, Tainsky MA. The oncogenic forms of N-ras or H-ras prevent skeletal myoblast differentiation Molecular and Cellular Biology. 7: 2104-2111. PMID 3600660 DOI: 10.1128/mcb.7.6.2104-2111.1987 |
0.302 |
|
1987 |
Tainsky MA, Shamanski FL, Blair D, Vande Woude G. Human recipient cell for oncogene transfection studies. Molecular and Cellular Biology. 7: 1280-4. PMID 3470599 |
0.307 |
|
1987 |
Tainsky MA, Shamanski F, Blair D, Giovanella BC. Causal role for an activated N-ras oncogene in the induction of tumorigenicity acquired by a human cell line. Cancer Research. 47: 3235-8. PMID 3034405 |
0.339 |
|
1986 |
O'Hara BM, Oskarsson M, Tainsky MA, Blair DG. Mechanism of Activation of Human ras Genes Cloned from a Gastric Adenocarcinoma and a Pancreatic Carcinoma Cell Line Cancer Research. 46: 4695-4700. PMID 3731120 |
0.371 |
|
1984 |
Tainsky MA, Cooper CS, Giovanella BC, Vande Woude GF. An activated rasN Gene: Detected in late but not early passage human PA1 teratocarcinoma cells Science. 225: 643-645. PMID 6740333 DOI: 10.1126/Science.6740333 |
0.469 |
|
1984 |
Cooper CS, Park M, Blair DG, Tainsky MA, Huebner K, Croce CM, Vande Woude GF. Molecular cloning of a new transforming gene from a chemically transformed human cell line Nature. 311: 29-33. PMID 6590967 DOI: 10.1038/311029A0 |
0.31 |
|
1984 |
Cooper CS, Blair DG, Oskarsson MK, Tainsky MA, Eader LA, Vande Woude GF. Characterization of Human Transforming Genes from Chemically Transformed, Teratocarcinoma, and Pancreatic Carcinoma Cell Lines Cancer Research. 44: 1-10. PMID 6418375 |
0.354 |
|
1981 |
Hampar B, Derge JG, Boyd AL, Tainsky MA, Showalter SD. Herpes simplex virus (type 1) thymidine kinase gene does not transform cells morphologically. Proceedings of the National Academy of Sciences of the United States of America. 78: 2616-9. PMID 6264486 DOI: 10.1073/pnas.78.4.2616 |
0.317 |
|
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