Richard D. LeDuc, Ph.D. - Publications

Affiliations: 
2007 University of Illinois, Urbana-Champaign, Urbana-Champaign, IL 
Area:
Bioinformatics Biology

38 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 LeDuc RD, Deutsch EW, Binz PA, Fellers RT, Cesnik AJ, Klein JA, Van Den Bossche T, Gabriels R, Yalavarthi A, Perez-Riverol Y, Carver J, Bittremieux W, Kawano S, Pullman B, Bandeira N, et al. Proteomics Standards Initiative's ProForma 2.0: Unifying the Encoding of Proteoforms and Peptidoforms. Journal of Proteome Research. PMID 35290070 DOI: 10.1021/acs.jproteome.1c00771  0.315
2020 Ives A, Su T, Durbin KR, Early BP, Dos Santos Seckler H, Fellers RT, LeDuc RD, Schachner LF, Patrie SM, Kelleher NL. Using 10,000 fragment ions to inform scoring in native top-down proteomics. Journal of the American Society For Mass Spectrometry. PMID 32436704 DOI: 10.1021/Jasms.0C00026  0.409
2019 Henning NF, LeDuc RD, Even KA, Laronda MM. Proteomic analyses of decellularized porcine ovaries identified new matrisome proteins and spatial differences across and within ovarian compartments. Scientific Reports. 9: 20001. PMID 31882863 DOI: 10.1038/S41598-019-56454-3  0.388
2019 Smith LM, Thomas PM, Shortreed MR, Schaffer LV, Fellers RT, LeDuc RD, Tucholski T, Ge Y, Agar JN, Anderson LC, Chamot-Rooke J, Gault J, Loo JA, Paša-Tolić L, Robinson CV, et al. A five-level classification system for proteoform identifications. Nature Methods. PMID 31451767 DOI: 10.1038/S41592-019-0573-X  0.358
2019 Schaffer LV, Millikin RJ, Miller RM, Anderson LC, Fellers RT, Ge Y, Kelleher NL, LeDuc RD, Liu X, Payne SH, Sun L, Thomas PM, Tucholski T, Wang Z, Wu S, et al. Identification and Quantification of Proteoforms by Mass Spectrometry. Proteomics. e1800361. PMID 31050378 DOI: 10.1002/Pmic.201800361  0.422
2019 LeDuc RD, Fellers RT, Early BP, Greer JB, Shams DP, Thomas P, Kelleher NL. Accurate Estimation of Context-Dependent False Discovery Rates in Top-Down Proteomics. Molecular & Cellular Proteomics : McP. PMID 30647073 DOI: 10.1074/Mcp.Ra118.000993  0.354
2019 Schaffer LV, Millikin RJ, Miller RM, Anderson LC, Fellers RT, Ge Y, Kelleher NL, LeDuc RD, Liu X, Payne SH, Sun L, Thomas PM, Tucholski T, Wang Z, Wu S, et al. Back Cover: Identification and Quantification of Proteoforms by Mass Spectrometry Proteomics. 19: 1970085. DOI: 10.1002/Pmic.201970085  0.35
2018 Riley NM, Sikora JW, Seckler HS, Greer JB, Fellers RT, LeDuc RD, Westphall MS, Thomas PM, Kelleher NL, Coon JJ. The Value of Activated Ion Electron Transfer Dissociation for High-Throughput Top-Down Characterization of Intact Proteins. Analytical Chemistry. PMID 29924586 DOI: 10.1021/Acs.Analchem.8B01638  0.416
2018 Davis RG, Park HM, Kim K, Greer JB, Fellers RT, LeDuc RD, Romanova EV, Rubakhin SS, Zombeck JA, Wu C, Yau PM, Gao P, van Nispen AJ, Patrie SM, Thomas PM, et al. Top-Down Proteomics Enables Comparative Analysis of Brain Proteoforms Between Mouse Strains. Analytical Chemistry. PMID 29481055 DOI: 10.1021/Acs.Analchem.7B04108  0.338
2018 LeDuc RD, Schwämmle V, Shortreed MR, Cesnik AJ, Solntsev SK, Shaw JB, Martin MJ, Vizcaíno JA, Alpi E, Danis P, Kelleher NL, Smith LM, Ge Y, Agar JN, Chamot-Rooke J, et al. ProForma: a Standard Proteoform Notation. Journal of Proteome Research. PMID 29397739 DOI: 10.1021/Acs.Jproteome.7B00851  0.325
2017 Toby TK, Abecassis M, Kim K, Thomas PM, Fellers RT, LeDuc RD, Kelleher NL, Demetris J, Levitsky J. Proteoforms in Peripheral Blood Mononuclear Cells as Novel Rejection Biomarkers in Liver Transplant Recipients. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. PMID 28510335 DOI: 10.1111/Ajt.14359  0.335
2017 Cleland TP, DeHart CJ, Fellers RT, VanNispen AJ, Greer JB, LeDuc RD, Parker WR, Thomas PM, Kelleher NL, Brodbelt JS. High-throughput analysis of intact human proteins using UVPD and HCD on an Orbitrap mass spectrometer. Journal of Proteome Research. PMID 28412815 DOI: 10.1021/Acs.Jproteome.7B00043  0.45
2017 Haverland NA, Skinner OS, Fellers RT, Tariq AA, Early BP, LeDuc RD, Fornelli L, Compton PD, Kelleher NL. Defining Gas-Phase Fragmentation Propensities of Intact Proteins During Native Top-Down Mass Spectrometry. Journal of the American Society For Mass Spectrometry. PMID 28374312 DOI: 10.1007/S13361-017-1635-X  0.39
2017 Fornelli L, Durbin KR, Fellers RT, Early BP, Greer JB, LeDuc RD, Compton PD, Kelleher NL. Advancing Top-down Analysis of the Human Proteome Using a Benchtop Quadrupole-Orbitrap Mass Spectrometer. Journal of Proteome Research. 16: 609-618. PMID 28152595 DOI: 10.1021/Acs.Jproteome.6B00698  0.421
2016 Anderson LC, DeHart CJ, Kaiser NK, Fellers RT, Smith DF, Greer JB, LeDuc RD, Blakney GT, Thomas PM, Kelleher NL, Hendrickson CL. Identification and Characterization of Human Proteoforms by Top-Down LC-21 Tesla FT-ICR Mass Spectrometry. Journal of Proteome Research. PMID 27936753 DOI: 10.1021/Acs.Jproteome.6B00696  0.386
2016 Savaryn JP, Toby TK, Catherman AD, Fellers RT, LeDuc RD, Thomas PM, Friedewald JJ, Salomon DR, Abecassis MM, Kelleher NL. Comparative top down proteomics of peripheral blood mononuclear cells from kidney transplant recipients with normal kidney biopsies or acute rejection. Proteomics. PMID 27120713 DOI: 10.1002/Pmic.201600008  0.376
2016 Ntai I, Toby TK, LeDuc RD, Kelleher NL. A Method for Label-Free, Differential Top-Down Proteomics. Methods in Molecular Biology (Clifton, N.J.). 1410: 121-33. PMID 26867742 DOI: 10.1007/978-1-4939-3524-6_8  0.415
2016 Skinner OS, Havugimana PC, Haverland NA, Fornelli L, Early BP, Greer JB, Fellers RT, Durbin KR, Do Vale LH, Melani RD, Seckler HS, Nelp MT, Belov ME, Horning SR, Makarov AA, ... LeDuc RD, et al. An informatic framework for decoding protein complexes by top-down mass spectrometry. Nature Methods. PMID 26780093 DOI: 10.1038/Nmeth.3731  0.428
2015 Ntai I, LeDuc RD, Fellers RT, Erdmann-Gilmore P, Davies SR, Rumsey J, Early BP, Thomas PM, Li S, Compton PD, Ellis MJ, Ruggles KV, Fenyo D, Boja ES, Rodriguez H, et al. Integrated Bottom-up and Top-down Proteomics of Patient-derived Breast Tumor Xenografts. Molecular & Cellular Proteomics : McP. PMID 26503891 DOI: 10.1074/Mcp.M114.047480  0.417
2015 Fellers RT, Greer JB, Early BP, Yu X, LeDuc RD, Kelleher NL, Thomas PM. ProSight Lite: graphical software to analyze top-down mass spectrometry data. Proteomics. 15: 1235-8. PMID 25828799 DOI: 10.1002/Pmic.201400313  0.403
2015 Wildburger NC, Ali SR, Hsu WC, Shavkunov AS, Nenov MN, Lichti CF, LeDuc RD, Mostovenko E, Panova-Elektronova NI, Emmett MR, Nilsson CL, Laezza F. Quantitative proteomics reveals protein-protein interactions with fibroblast growth factor 12 as a component of the voltage-gated sodium channel 1.2 (nav1.2) macromolecular complex in Mammalian brain. Molecular & Cellular Proteomics : McP. 14: 1288-300. PMID 25724910 DOI: 10.1074/Mcp.M114.040055  0.308
2014 Kelleher NL, Thomas PM, Ntai I, Compton PD, LeDuc RD. Deep and quantitative top-down proteomics in clinical and translational research. Expert Review of Proteomics. 11: 649-51. PMID 25347991 DOI: 10.1586/14789450.2014.976559  0.384
2014 LeDuc RD, Fellers RT, Early BP, Greer JB, Thomas PM, Kelleher NL. The C-score: a Bayesian framework to sharply improve proteoform scoring in high-throughput top down proteomics. Journal of Proteome Research. 13: 3231-40. PMID 24922115 DOI: 10.1021/Pr401277R  0.332
2014 Ntai I, Kim K, Fellers RT, Skinner OS, Smith AD, Early BP, Savaryn JP, LeDuc RD, Thomas PM, Kelleher NL. Applying label-free quantitation to top down proteomics. Analytical Chemistry. 86: 4961-8. PMID 24807621 DOI: 10.1021/Ac500395K  0.396
2014 Dang X, Scotcher J, Wu S, Chu RK, Tolić N, Ntai I, Thomas PM, Fellers RT, Early BP, Zheng Y, Durbin KR, Leduc RD, Wolff JJ, Thompson CJ, Pan J, et al. The first pilot project of the consortium for top-down proteomics: a status report. Proteomics. 14: 1130-40. PMID 24644084 DOI: 10.1002/Pmic.201300438  0.356
2013 Haas BJ, Papanicolaou A, Yassour M, Grabherr M, Blood PD, Bowden J, Couger MB, Eccles D, Li B, Lieber M, Macmanes MD, Ott M, Orvis J, Pochet N, Strozzi F, ... ... Leduc RD, et al. De novo transcript sequence reconstruction from RNA-seq using the Trinity platform for reference generation and analysis. Nature Protocols. 8: 1494-512. PMID 23845962 DOI: 10.1038/Nprot.2013.084  0.322
2011 Tran JC, Zamdborg L, Ahlf DR, Lee JE, Catherman AD, Durbin KR, Tipton JD, Vellaichamy A, Kellie JF, Li M, Wu C, Sweet SM, Early BP, Siuti N, LeDuc RD, et al. Mapping intact protein isoforms in discovery mode using top-down proteomics. Nature. 480: 254-8. PMID 22037311 DOI: 10.1038/Nature10575  0.447
2011 Townsend RR, Rohrs H, LeDuc R, Malone JP, Erdman-Gilmore P, Hill DL, Grubbs CJ, You M, Lubet RA. Abstract 3700: Proteomic credentialing in a model for chemoprevention studies of urinary bladder cancer Cancer Research. 71: 3700-3700. DOI: 10.1158/1538-7445.Am2011-3700  0.364
2010 Nittis T, Guittat L, LeDuc RD, Dao B, Duxin JP, Rohrs H, Townsend RR, Stewart SA. Revealing novel telomere proteins using in vivo cross-linking, tandem affinity purification, and label-free quantitative LC-FTICR-MS. Molecular & Cellular Proteomics : McP. 9: 1144-56. PMID 20097687 DOI: 10.1074/Mcp.M900490-Mcp200  0.439
2009 Hiken J, LeDuc R, Gilmore P, Rohrs H, Townsend RR, Bessler M. Global Differences in RBC Membrane Protein Expression Between Normal and PNH Individuals. Blood. 114: 1986-1986. DOI: 10.1182/Blood.V114.22.1986.1986  0.342
2009 Townsend R, Rohrs H, Leduc R, Yi Y, Yao R, Malone J, Edrman-Gilmore P, Grubbs C, You M, Lubet R. Identification of urinary biomarkers to distinguish tumor bearing and control rats in the methylnitrosourea (MNU) – induced model of mammary carcinogenesis: use of label-free, comparative, ultra-high resolution nano-LC mass spectrometry. Cancer Research. 69: 1109. DOI: 10.1158/0008-5472.Sabcs-1109  0.322
2008 Pesavento JJ, Bullock CR, LeDuc RD, Mizzen CA, Kelleher NL. Combinatorial modification of human histone H4 quantitated by two-dimensional liquid chromatography coupled with top down mass spectrometry. The Journal of Biological Chemistry. 283: 14927-37. PMID 18381279 DOI: 10.1074/Jbc.M709796200  0.368
2007 Leduc RD, Kelleher NL. Using ProSight PTM and related tools for targeted protein identification and characterization with high mass accuracy tandem MS data. Current Protocols in Bioinformatics / Editoral Board, Andreas D. Baxevanis ... [Et Al.]. Unit 13.6. PMID 18428787 DOI: 10.1002/0471250953.Bi1306S19  0.454
2007 Martin N, Ruedi EA, Leduc R, Sun FJ, Caetano-Anollés G. Gene-interleaving patterns of synteny in the Saccharomyces cerevisiae genome: are they proof of an ancient genome duplication event? Biology Direct. 2: 23. PMID 17894859 DOI: 10.1186/1745-6150-2-23  0.476
2007 Zamdborg L, LeDuc RD, Glowacz KJ, Kim YB, Viswanathan V, Spaulding IT, Early BP, Bluhm EJ, Babai S, Kelleher NL. ProSight PTM 2.0: improved protein identification and characterization for top down mass spectrometry. Nucleic Acids Research. 35: W701-6. PMID 17586823 DOI: 10.1093/Nar/Gkm371  0.452
2005 Methogo RM, Dufresne-Martin G, Leclerc P, Leduc R, Klarskov K. Mass spectrometric peptide fingerprinting of proteins after Western blotting on polyvinylidene fluoride and enhanced chemiluminescence detection. Journal of Proteome Research. 4: 2216-24. PMID 16335969 DOI: 10.1021/pr050014+  0.321
2005 Zabrouskov V, Senko MW, Du Y, Leduc RD, Kelleher NL. New and automated MSn approaches for top-down identification of modified proteins. Journal of the American Society For Mass Spectrometry. 16: 2027-38. PMID 16253516 DOI: 10.1016/J.Jasms.2005.08.004  0.421
2004 LeDuc RD, Taylor GK, Kim YB, Januszyk TE, Bynum LH, Sola JV, Garavelli JS, Kelleher NL. ProSight PTM: an integrated environment for protein identification and characterization by top-down mass spectrometry. Nucleic Acids Research. 32: W340-5. PMID 15215407 DOI: 10.1093/Nar/Gkh447  0.446
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