☰

Natarajan V Bhanu - Publications

Affiliations: 
Washington University, Saint Louis, St. Louis, MO 
Area:
TB, hematology, stem cell, Epigenetics, histone PTMs
Tree Info Similar researchers PubMed Report error

57 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Fernandez-Rojas M, Fuller CN, Valadares Tose L, Willetts M, Park MA, Bhanu NV, Garcia BA, Fernandez-Lima F. Histone Modification Screening using Liquid Chromatography, Trapped Ion Mobility Spectrometry, and Time-Of-Flight Mass Spectrometry. Journal of Visualized Experiments : Jove. PMID 38284546 DOI: 10.3791/65589  0.516
2023 Park S, Athreya A, Carrizo GE, Benning NA, Mitchener MM, Bhanu NV, Garcia BA, Zhang B, Muir TW, Pearce EL, Ha T. Electrostatic encoding of genome organization principles within single native nucleosomes. Biorxiv : the Preprint Server For Biology. PMID 38106048 DOI: 10.1101/2023.12.08.570828  0.519
2023 Crawford MC, Tripu DR, Barritt SA, Jing Y, Gallimore D, Kales SC, Bhanu NV, Xiong Y, Fang Y, Butler KAT, LeClair CA, Coussens NP, Simeonov A, Garcia BA, Dibble CC, et al. Comparative Analysis of Drug-like EP300/CREBBP Acetyltransferase Inhibitors. Acs Chemical Biology. PMID 37737090 DOI: 10.1021/acschembio.3c00293  0.477
2023 Lu-Culligan WJ, Connor LJ, Xie Y, Ekundayo BE, Rose BT, Machyna M, Pintado-Urbanc AP, Zimmer JT, Vock IW, Bhanu NV, King MC, Garcia BA, Bleichert F, Simon MD. Acetyl-methyllysine marks chromatin at active transcription start sites. Nature. PMID 37731000 DOI: 10.1038/s41586-023-06565-9  0.578
2023 Crawford MC, Tripu DR, Barritt SA, Jing Y, Gallimore D, Kales SC, Bhanu NV, Xiong Y, Fang Y, Butler KAT, LeClair CA, Coussens NP, Simeonov A, Garcia BA, Dibble CC, et al. Comparative analysis of drug-like EP300/CREBBP acetyltransferase inhibitors. Biorxiv : the Preprint Server For Biology. PMID 37292747 DOI: 10.1101/2023.05.15.540887  0.477
2022 Jeanne Dit Fouque K, Miller SA, Pham K, Bhanu NV, Cintron-Diaz YL, Leyva D, Kaplan D, Voinov VG, Ridgeway ME, Park MA, Garcia BA, Fernandez-Lima F. Top-"Double-Down" Mass Spectrometry of Histone H4 Proteoforms: Tandem Ultraviolet-Photon and Mobility/Mass-Selected Electron Capture Dissociations. Analytical Chemistry. 94: 15377-15385. PMID 36282112 DOI: 10.1021/acs.analchem.2c03147  0.483
2022 Zijlmans DW, Talon I, Verhelst S, Bendall A, Van Nerum K, Javali A, Malcolm AA, van Knippenberg SSFA, Biggins L, To SK, Janiszewski A, Admiraal D, Knops R, Corthout N, Balaton BP, ... ... Bhanu NV, et al. Integrated multi-omics reveal polycomb repressive complex 2 restricts human trophoblast induction. Nature Cell Biology. 24: 858-871. PMID 35697783 DOI: 10.1038/s41556-022-00932-w  0.538
2022 Drosos Y, Myers JA, Xu B, Mathias KM, Beane EC, Radko-Juettner S, Mobley RJ, Larsen ME, Piccioni F, Ma X, Low J, Hansen BS, Peters ST, Bhanu NV, Dhanda SK, et al. NSD1 mediates antagonism between SWI/SNF and polycomb complexes and is required for transcriptional activation upon EZH2 inhibition. Molecular Cell. PMID 35537449 DOI: 10.1016/j.molcel.2022.04.015  0.491
2022 Farrelly LA, Zheng S, Schrode N, Topol A, Bhanu NV, Bastle RM, Ramakrishnan A, Chan JC, Cetin B, Flaherty E, Shen L, Gleason K, Tamminga CA, Garcia BA, Li H, et al. Chromatin profiling in human neurons reveals aberrant roles for histone acetylation and BET family proteins in schizophrenia. Nature Communications. 13: 2195. PMID 35459277 DOI: 10.1038/s41467-022-29922-0  0.503
2021 Yang E, Bu W, Suma A, Carnevale V, Grasty KC, Loll PJ, Woll K, Bhanu N, Garcia BA, Eckenhoff RG, Covarrubias M. Binding Sites and the Mechanism of Action of Propofol and a Photoreactive Analogue in Prokaryotic Voltage-Gated Sodium Channels. Acs Chemical Neuroscience. 12: 3898-3914. PMID 34607428 DOI: 10.1021/acschemneuro.1c00495  0.376
2020 Bhanu NV, Sidoli S, Garcia BA. A Workflow for Ultra-rapid Analysis of Histone Post-translational Modifications with Direct-injection Mass Spectrometry. Bio-Protocol. 10: e3756. PMID 33659415 DOI: 10.21769/BioProtoc.3756  0.678
2020 White ER, Leace DM, Bedell VM, Bhanu NV, Garcia BA, Dailey WP, Eckenhoff RG. Synthesis and Characterization of a Diazirine-Based Photolabel of the Nonanesthetic Fropofol. Acs Chemical Neuroscience. PMID 33355437 DOI: 10.1021/acschemneuro.0c00667  0.35
2020 Wague A, Joseph TT, Woll KA, Bu W, Vaidya KA, Bhanu NV, Garcia BA, Nimigean CM, Eckenhoff RG, Riegelhaupt PM. Mechanistic insights into volatile anesthetic modulation of K2P channels. Elife. 9. PMID 33345771 DOI: 10.7554/eLife.59839  0.364
2020 Li J, Yuan S, Norgard RJ, Yan F, Sun YH, Kim IK, Merrell AJ, Sela Y, Jiang Y, Bhanu NV, Garcia BA, Vonderheide RH, Blanco A, Stanger BZ. Epigenetic and transcriptional control of the epidermal growth factor receptor (EGFR) regulates the tumor immune microenvironment in pancreatic cancer. Cancer Discovery. PMID 33158848 DOI: 10.1158/2159-8290.CD-20-0519  0.417
2020 Dobenecker MW, Marcello J, Becker A, Rudensky E, Bhanu NV, Carrol T, Garcia BA, Prinjha R, Yurchenko V, Tarakhovsky A. The catalytic domain of the histone methyltransferase NSD2/MMSET is required for the generation of B1 cells in mice. Febs Letters. PMID 32862441 DOI: 10.1002/1873-3468.13903  0.413
2020 Khoa LTP, Tsan YC, Mao F, Kremer DM, Sajjakulnukit P, Zhang L, Zhou B, Tong X, Bhanu NV, Choudhary C, Garcia BA, Yin L, Smith GD, Saunders TL, Bielas SL, et al. Histone Acetyltransferase MOF Blocks Acquisition of Quiescence in Ground-State ESCs through Activating Fatty Acid Oxidation. Cell Stem Cell. PMID 32610040 DOI: 10.1016/J.Stem.2020.06.005  0.433
2020 Rezazadeh S, Yang D, Biashad SA, Firsanov D, Takasugi M, Gilbert M, Tombline G, Bhanu NV, Garcia BA, Seluanov A, Gorbunova V. SIRT6 mono-ADP ribosylates KDM2A to locally increase H3K36me2 at DNA damage sites to inhibit transcription and promote repair. Aging. 12. PMID 32584788 DOI: 10.18632/aging.103567  0.43
2020 Chan JC, Morgan CP, Adrian Leu N, Shetty A, Cisse YM, Nugent BM, Morrison KE, Jašarević E, Huang W, Kanyuch N, Rodgers AB, Bhanu NV, Berger DS, Garcia BA, Ament S, et al. Reproductive tract extracellular vesicles are sufficient to transmit intergenerational stress and program neurodevelopment. Nature Communications. 11: 1499. PMID 32198406 DOI: 10.1038/S41467-020-15305-W  0.369
2020 Yuan S, Natesan R, Sanchez-Rivera FJ, Li J, Bhanu NV, Yamazoe T, Lin JH, Merrell AJ, Sela Y, Thomas SK, Jiang Y, Plesset JB, Miller EM, Shi J, Garcia BA, et al. Global regulation of the histone mark H3K36me2 underlies epithelial plasticity and metastatic progression. Cancer Discovery. PMID 32188706 DOI: 10.1158/2159-8290.Cd-19-1299  0.532
2019 Iglesias N, Paulo JA, Tatarakis A, Wang X, Edwards AL, Bhanu NV, Garcia BA, Haas W, Gygi SP, Moazed D. Native Chromatin Proteomics Reveals a Role for Specific Nucleoporins in Heterochromatin Organization and Maintenance. Molecular Cell. PMID 31784357 DOI: 10.1016/J.Molcel.2019.10.018  0.5
2019 Gowans GJ, Bridgers JB, Zhang J, Dronamraju R, Burnetti A, King DA, Thiengmany AV, Shinsky SA, Bhanu NV, Garcia BA, Buchler NE, Strahl BD, Morrison AJ. Recognition of Histone Crotonylation by Taf14 Links Metabolic State to Gene Expression. Molecular Cell. PMID 31676231 DOI: 10.1016/J.Molcel.2019.09.029  0.509
2019 McKinstry-Wu A, Woll KA, Joseph T, Bu W, White ER, Bhanu NV, Garcia BA, Brannigan G, Dailey WP, Eckenhoff RG. Azi-medetomidine: Synthesis and Characterization of a Novel α2 Adrenergic Photoaffinity Ligand. Acs Chemical Neuroscience. PMID 31638765 DOI: 10.1021/Acschemneuro.9B00484  0.344
2019 Sidoli S, Lopes M, Lund PJ, Goldman N, Fasolino M, Coradin M, Kulej K, Bhanu NV, Vahedi G, Garcia BA. A mass spectrometry-based assay using metabolic labeling to rapidly monitor chromatin accessibility of modified histone proteins. Scientific Reports. 9: 13613. PMID 31541121 DOI: 10.1038/S41598-019-49894-4  0.7
2019 Ren Z, Ahn JH, Liu H, Tsai YH, Bhanu NV, Koss B, Allison DF, Ma A, Storey AJ, Wang P, Mackintosh SG, Edmondson RD, Groen RWJ, Martens AC, Garcia BA, et al. PHF19 promotes multiple myeloma tumorigenicity through PRC2 activation. Blood. PMID 31383640 DOI: 10.1182/Blood.2019000578  0.503
2019 Behera V, Stonestrom AJ, Hamagami N, Hsiung CC, Keller CA, Giardine B, Sidoli S, Yuan ZF, Bhanu NV, Werner MT, Wang H, Garcia BA, Hardison RC, Blobel GA. Interrogating Histone Acetylation and BRD4 as Mitotic Bookmarks of Transcription. Cell Reports. 27: 400-415.e5. PMID 30970245 DOI: 10.1016/J.Celrep.2019.03.057  0.69
2019 Bhanu NV, Sidoli S, Yuan ZF, Molden RC, Garcia BA. Regulation of proline-directed kinases and the trans-histone code H3K9me3/H4K20me3 during human myogenesis. The Journal of Biological Chemistry. PMID 30872405 DOI: 10.1074/Jbc.Ra118.004977  0.693
2019 Farrelly LA, Thompson RE, Zhao S, Lepack AE, Lyu Y, Bhanu NV, Zhang B, Loh YE, Ramakrishnan A, Vadodaria KC, Heard KJ, Erikson G, Nakadai T, Bastle RM, Lukasak BJ, et al. Histone serotonylation is a permissive modification that enhances TFIID binding to H3K4me3. Nature. PMID 30867594 DOI: 10.1038/S41586-019-1024-7  0.542
2018 Zhang H, Pandey S, Travers M, Sun H, Morton G, Madzo J, Chung W, Khowsathit J, Perez-Leal O, Barrero CA, Merali C, Okamoto Y, Sato T, Pan J, Garriga J, ... Bhanu NV, et al. Targeting CDK9 Reactivates Epigenetically Silenced Genes in Cancer. Cell. 175: 1244-1258.e26. PMID 30454645 DOI: 10.1016/J.Cell.2018.09.051  0.47
2018 Li ML, Jiang Q, Bhanu NV, Wu J, Li W, Garcia BA, Greenberg RA. Phosphorylation of TIP60 suppresses 53BP1 localization at DNA damage sites. Molecular and Cellular Biology. PMID 30297459 DOI: 10.1128/MCB.00209-18  0.471
2018 Woll KA, Guzik-Lendrum S, Bensel BM, Bhanu NV, Dailey WP, Garcia BA, Gilbert SP, Eckenhoff RG. An allosteric propofol-binding site in kinesin disrupts kinesin-mediated processive movement on microtubules. The Journal of Biological Chemistry. PMID 29844014 DOI: 10.1074/Jbc.Ra118.002182  0.368
2018 Lee CH, Yu JR, Kumar S, Jin Y, LeRoy G, Bhanu N, Kaneko S, Garcia BA, Hamilton AD, Reinberg D. Allosteric Activation Dictates PRC2 Activity Independent of Its Recruitment to Chromatin. Molecular Cell. PMID 29681499 DOI: 10.1016/J.Molcel.2018.03.020  0.45
2018 Woll KA, Zhou X, Bhanu NV, Garcia BA, Covarrubias M, Miller KW, Eckenhoff RG. Identification of binding sites contributing to volatile anesthetic effects on GABA type A receptors. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201701347R. PMID 29505303 DOI: 10.1096/Fj.201701347R  0.353
2017 Tan L, Ke Z, Tombline G, Macoretta N, Hayes K, Tian X, Lv R, Ablaeva J, Gilbert M, Bhanu NV, Yuan ZF, Garcia BA, Shi YG, Shi Y, Seluanov A, et al. Naked Mole Rat Cells Have a Stable Epigenome that Resists iPSC Reprogramming. Stem Cell Reports. PMID 29107597 DOI: 10.1016/J.Stemcr.2017.10.001  0.475
2017 Simithy J, Sidoli S, Yuan ZF, Coradin M, Bhanu NV, Marchione DM, Klein BJ, Bazilevsky GA, McCullough CE, Magin RS, Kutateladze TG, Snyder NW, Marmorstein R, Garcia BA. Characterization of histone acylations links chromatin modifications with metabolism. Nature Communications. 8: 1141. PMID 29070843 DOI: 10.1038/S41467-017-01384-9  0.678
2017 Woll KA, Skinner KA, Gianti E, Bhanu NV, Garcia BA, Carnevale V, Eckenhoff RG, Gaudet R. Sites Contributing to TRPA1 Activation by the Anesthetic Propofol Identified by Photoaffinity Labeling. Biophysical Journal. PMID 28935134 DOI: 10.1016/J.Bpj.2017.08.040  0.388
2017 Jih G, Iglesias N, Currie MA, Bhanu NV, Paulo JA, Gygi SP, Garcia BA, Moazed D. Unique roles for histone H3K9me states in RNAi and heritable silencing of transcription. Nature. PMID 28682306 DOI: 10.1038/Nature23267  0.518
2017 Dalvi MP, Wang L, Zhong R, Kollipara RK, Park H, Bayo J, Yenerall P, Zhou Y, Timmons BC, Rodriguez-Canales J, Behrens C, Mino B, Villalobos P, Parra ER, Suraokar M, ... ... Bhanu NV, et al. Taxane-Platin-Resistant Lung Cancers Co-develop Hypersensitivity to JumonjiC Demethylase Inhibitors. Cell Reports. 19: 1669-1684. PMID 28538184 DOI: 10.1016/J.Celrep.2017.04.077  0.43
2017 Dorighi KM, Swigut T, Henriques T, Bhanu NV, Scruggs BS, Nady N, Still CD, Garcia BA, Adelman K, Wysocka J. Mll3 and Mll4 Facilitate Enhancer RNA Synthesis and Transcription from Promoters Independently of H3K4 Monomethylation. Molecular Cell. PMID 28483418 DOI: 10.1016/J.Molcel.2017.04.018  0.535
2017 Woll KA, Peng W, Liang Q, Zhi L, Jacobs JA, Maciunas L, Bhanu N, Garcia BA, Covarrubias M, Loll PJ, Dailey WP, Eckenhoff RG. Photoaffinity ligand for the inhalational anesthetic sevoflurane allows mechanistic insight into potassium channel modulation. Acs Chemical Biology. PMID 28333442 DOI: 10.1021/Acschembio.7B00222  0.367
2016 Sidoli S, Bhanu NV, Karch KR, Wang X, Garcia BA. Complete Workflow for Analysis of Histone Post-translational Modifications Using Bottom-up Mass Spectrometry: From Histone Extraction to Data Analysis. Journal of Visualized Experiments : Jove. PMID 27286567 DOI: 10.3791/54112  0.694
2016 Zhou B, Wang J, Lee SY, Xiong J, Bhanu N, Guo Q, Ma P, Sun Y, Rao RC, Garcia BA, Hess JL, Dou Y. PRDM16 Suppresses MLL1r Leukemia via Intrinsic Histone Methyltransferase Activity. Molecular Cell. PMID 27151440 DOI: 10.1016/j.molcel.2016.03.010  0.516
2016 Garcia BA, Luka Z, Loukachevitch LV, Bhanu NV, Wagner C. Folate deficiency affects histone methylation. Medical Hypotheses. 88: 63-7. PMID 26880641 DOI: 10.1016/j.mehy.2015.12.027  0.515
2016 Gonzales-Cope M, Sidoli S, Bhanu NV, Won KJ, Garcia BA. Histone H4 acetylation and the epigenetic reader Brd4 are critical regulators of pluripotency in embryonic stem cells. Bmc Genomics. 17: 95. PMID 26847871 DOI: 10.1186/S12864-016-2414-Y  0.692
2015 Bhanu NV, Sidoli S, Garcia BA. Histone modification profiling reveals differential signatures associated with human embryonic stem cell self-renewal and differentiation. Proteomics. PMID 26631989 DOI: 10.1002/Pmic.201500231  0.65
2015 Molden RC, Bhanu NV, LeRoy G, Arnaudo AM, Garcia BA. Multi-faceted quantitative proteomics analysis of histone H2B isoforms and their modifications. Epigenetics & Chromatin. 8: 15. PMID 25922622 DOI: 10.1186/S13072-015-0006-8  0.578
2015 Yuan ZF, Lin S, Molden RC, Cao XJ, Bhanu NV, Wang X, Sidoli S, Liu S, Garcia BA. EpiProfile Quantifies Histone Peptides With Modifications by Extracting Retention Time and Intensity in High-resolution Mass Spectra. Molecular & Cellular Proteomics : McP. 14: 1696-707. PMID 25805797 DOI: 10.1074/Mcp.M114.046011  0.658
2015 Sidoli S, Yuan ZF, Lin S, Karch K, Wang X, Bhanu N, Arnaudo AM, Britton LM, Cao XJ, Gonzales-Cope M, Han Y, Liu S, Molden RC, Wein S, Afjehi-Sadat L, et al. Drawbacks in the use of unconventional hydrophobic anhydrides for histone derivatization in bottom-up proteomics PTM analysis. Proteomics. 15: 1459-69. PMID 25641854 DOI: 10.1002/Pmic.201400483  0.655
2015 Sidoli S, Lin S, Xiong L, Bhanu NV, Karch KR, Johansen E, Hunter C, Mollah S, Garcia BA. SWATH Analysis for Characterization and Quantification of Histone Post-translational Modifications. Molecular & Cellular Proteomics : McP. PMID 25636311 DOI: 10.1074/Mcp.O114.046102  0.662
2013 Britton LM, Newhart A, Bhanu NV, Sridharan R, Gonzales-Cope M, Plath K, Janicki SM, Garcia BA. Initial characterization of histone H3 serine 10 O-acetylation. Epigenetics : Official Journal of the Dna Methylation Society. 8: 1101-13. PMID 23949383 DOI: 10.4161/Epi.26025  0.554
2009 Sripichai O, Kiefer CM, Bhanu NV, Tanno T, Noh SJ, Goh SH, Russell JE, Rognerud CL, Ou CN, Oneal PA, Meier ER, Gantt NM, Byrnes C, Lee YT, Dean A, et al. Cytokine-mediated increases in fetal hemoglobin are associated with globin gene histone modification and transcription factor reprogramming. Blood. 114: 2299-306. PMID 19597182 DOI: 10.1182/Blood-2009-05-219386  0.691
2008 Bhanu NV, Lee YT, Oneal PA, Gantt NM, Aerbajinai W, Noel P, Thomas CJ, Miller JL. Inhibition of erythroblast growth and fetal hemoglobin production by ribofuranose-substituted adenosine derivatives. Biochimica Et Biophysica Acta. 1782: 504-10. PMID 18586086 DOI: 10.1016/J.Bbadis.2008.05.004  0.621
2007 Tanno T, Bhanu NV, Oneal PA, Goh SH, Staker P, Lee YT, Moroney JW, Reed CH, Luban NL, Wang RH, Eling TE, Childs R, Ganz T, Leitman SF, Fucharoen S, et al. High levels of GDF15 in thalassemia suppress expression of the iron regulatory protein hepcidin. Nature Medicine. 13: 1096-101. PMID 17721544 DOI: 10.1038/Nm1629  0.578
2007 Bhanu NV, Aerbajinai W, Gantt NM, Jackson EK, Goh SH, Terry Lee Y, Miller JL. Cl-IB-MECA inhibits human erythropoiesis. British Journal of Haematology. 137: 233-6. PMID 17408462 DOI: 10.1111/J.1365-2141.2007.06540.X  0.591
2006 Oneal PA, Gantt NM, Schwartz JD, Bhanu NV, Lee YT, Moroney JW, Reed CH, Schechter AN, Luban NL, Miller JL. Fetal hemoglobin silencing in humans. Blood. 108: 2081-6. PMID 16735596 DOI: 10.1182/Blood-2006-04-015859  0.625
2005 Goh SH, Lee YT, Bhanu NV, Cam MC, Desper R, Martin BM, Moharram R, Gherman RB, Miller JL. A newly discovered human alpha-globin gene. Blood. 106: 1466-72. PMID 15855277 DOI: 10.1182/blood-2005-03-0948  0.577
2005 Bhanu NV, Trice TA, Lee YT, Gantt NM, Oneal P, Schwartz JD, Noel P, Miller JL. A sustained and pancellular reversal of gamma-globin gene silencing in adult human erythroid precursor cells. Blood. 105: 387-93. PMID 15367428 DOI: 10.1182/blood-2004-04-1599  0.626
2004 Bhanu NV, Trice TA, Lee YT, Miller JL. A signaling mechanism for growth-related expression of fetal hemoglobin. Blood. 103: 1929-33. PMID 14592835 DOI: 10.1182/blood-2003-05-1624  0.57
Show low-probability matches.