Sriram Neelamegham - Publications

Chemical and Biological Engineering State University of New York, Buffalo, Buffalo, NY, United States 
Biomedical Engineering, Chemical Engineering

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Year Citation  Score
2019 Cheng K, Pawlowski G, Yu X, Zhou Y, Neelamegham S. DrawGlycan-SNFG & gpAnnotate: Rendering glycans and annotating glycopeptide mass spectra. Bioinformatics (Oxford, England). PMID 31710658 DOI: 10.1093/bioinformatics/btz819  0.56
2019 Kelkar A, Zhu Y, Groth T, Stolfa G, Stablewski AB, Singhi N, Nemeth M, Neelamegham S. Doxycycline-Dependent Self-Inactivation of CRISPR-Cas9 to Temporally Regulate On- and Off-Target Editing. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 31601489 DOI: 10.1016/j.ymthe.2019.09.006  0.36
2019 Irons EE, Lee-Sundlov MM, Zhu Y, Neelamegham S, Hoffmeister KM, Lau JT. B cells suppress medullary granulopoiesis by an extracellular glycosylation-dependent mechanism. Elife. 8. PMID 31408003 DOI: 10.7554/eLife.47328  0.36
2019 Chen Z, Lu J, Zhang C, Hsia I, Yu X, Marecki L, Marecki E, Asmani M, Jain S, Neelamegham S, Zhao R. Microclot array elastometry for integrated measurement of thrombus formation and clot biomechanics under fluid shear. Nature Communications. 10: 2051. PMID 31053712 DOI: 10.1038/s41467-019-10067-6  0.36
2019 Zhang C, Kelkar A, Neelamegham S. von Willebrand factor self-association is regulated by the shear-dependent unfolding of the A2 domain. Blood Advances. 3: 957-968. PMID 30936056 DOI: 10.1182/bloodadvances.2018030122  0.32
2019 Weil BR, Neelamegham S. Selectins and Immune Cells in Acute Myocardial Infarction and Post-infarction Ventricular Remodeling: Pathophysiology and Novel Treatments. Frontiers in Immunology. 10: 300. PMID 30873166 DOI: 10.3389/fimmu.2019.00300  0.32
2019 Nasirikenari M, Lugade AA, Neelamegham S, Gao Z, Moremen KW, Bogner PN, Thanavala Y, Lau JTY. Recombinant Sialyltransferase Infusion Mitigates Infection-Driven Acute Lung Inflammation. Frontiers in Immunology. 10: 48. PMID 30778346 DOI: 10.3389/fimmu.2019.00048  0.32
2018 Wang SS, Gao X, Solar VD, Yu X, Antonopoulos A, Friedman AE, Matich EK, Atilla-Gokcumen GE, Nasirikenari M, Lau JT, Dell A, Haslam SM, Laine RA, Matta KL, Neelamegham S. Thioglycosides Are Efficient Metabolic Decoys of Glycosylation that Reduce Selectin Dependent Leukocyte Adhesion. Cell Chemical Biology. PMID 30344053 DOI: 10.1016/j.chembiol.2018.09.012  0.36
2018 Chugh S, Barkeer S, Rachagani S, Nimmakayala RK, Perumal N, Pothuraju R, Atri P, Mahapatra S, Thapa I, Talmon GA, Smith LM, Yu X, Neelamegham S, Fu J, Xia L, et al. Disruption of C1galt1 Gene Promotes Development and Metastasis of Pancreatic Adenocarcinomas in Mice. Gastroenterology. PMID 30086262 DOI: 10.1053/j.gastro.2018.08.007  0.36
2017 Gogia S, Kelkar A, Zhang C, Dayananda KM, Neelamegham S. Role of calcium in regulating the intra- and extracellular cleavage of von Willebrand factor by the protease ADAMTS13. Blood Advances. 1: 2063-2074. PMID 29296853 DOI: 10.1182/bloodadvances.2017009027  0.64
2017 Zhang C, Kelkar A, Nasirikenari M, Lau JTY, Sveinsson M, Sharma UC, Pokharel S, Neelamegham S. The physical spacing between the von willebrand factor d'd3- and a1- domains regulates platelet adhesion in vitro and in vivo. Journal of Thrombosis and Haemostasis : Jth. PMID 29251812 DOI: 10.1111/jth.13927  0.32
2017 Liu G, Cheng K, Lo CY, Li J, Qu J, Neelamegham S. A comprehensive, open-source platform for mass spectrometry based glycoproteomics data analysis. Molecular & Cellular Proteomics : McP. PMID 28887379 DOI: 10.1074/mcp.M117.068239  0.64
2017 Zhang C, Neelamegham S. Application of microfluidic devices in studies of thrombosis and hemostasis. Platelets. 1-7. PMID 28580870 DOI: 10.1080/09537104.2017.1319047  0.32
2017 Cheng K, Zhou Y, Neelamegham S. DrawGlycan-SNFG: a robust tool to render glycans and glycopeptides with fragmentation information. Glycobiology. 27: 200-205. PMID 28177454 DOI: 10.1093/glycob/cww115  0.56
2016 Cheng K, Zhou Y, Neelamegham S. DrawGlycan-SNFG: a robust tool to render glycans and glycopeptides with fragmentation information. Glycobiology. PMID 27979998 DOI: 10.1093/glycob/cww115  0.56
2016 Buffone A, Nasirikenari M, Manhardt CT, Lugade A, Bogner PN, Sackstein R, Thanavala Y, Neelamegham S, Lau JT. Leukocyte-borne α(1,3)-fucose is a negative regulator of β2-integrin-dependent recruitment in lung inflammation. Journal of Leukocyte Biology. PMID 27566832 DOI: 10.1189/jlb.3A0516-215RR  0.56
2016 Stolfa G, Mondal N, Zhu Y, Yu X, Buffone A, Neelamegham S. Using CRISPR-Cas9 to quantify the contributions of O-glycans, N-glycans and Glycosphingolipids to human leukocyte-endothelium adhesion. Scientific Reports. 6: 30392. PMID 27458028 DOI: 10.1038/srep30392  1
2016 Chandrasekaran EV, Xue J, Xia J, Khaja SD, Piskorz CF, Locke RD, Neelamegham S, Matta KL. Novel interactions of complex carbohydrates with peanut (PNA), Ricinus communis (RCA-I), Sambucus nigra (SNA-I) and wheat germ (WGA) agglutinins as revealed by the binding specificities of these lectins towards mucin core-2 O-linked and N-linked glycans and related structures. Glycoconjugate Journal. PMID 27318477 DOI: 10.1007/s10719-016-9678-y  1
2016 Mondal N, Stolfa G, Antonopoulos A, Zhu Y, Wang SS, Buffone A, Atilla-Gokcumen GE, Haslam SM, Dell A, Neelamegham S. Glycosphingolipids on Human Myeloid Cells Stabilize E-Selectin-Dependent Rolling in the Multistep Leukocyte Adhesion Cascade. Arteriosclerosis, Thrombosis, and Vascular Biology. PMID 26868209 DOI: 10.1161/ATVBAHA.115.306748  1
2015 Gupta R, Matta KL, Neelamegham S. A systematic analysis of acceptor specificity and reaction kinetics of five human α(2,3)sialyltransferases: Product inhibition studies illustrate reaction mechanism for ST3Gal-I. Biochemical and Biophysical Research Communications. PMID 26692484 DOI: 10.1016/j.bbrc.2015.11.130  1
2015 Gogia S, Neelamegham S. Role of fluid shear stress in regulating VWF structure, function and related blood disorders. Biorheology. PMID 26600266 DOI: 10.3233/BIR-15061  0.64
2015 Lo CY, Weil BR, Palka BA, Momeni A, Canty JM, Neelamegham S. Cell surface glycoengineering improves selectin-mediated adhesion of mesenchymal stem cells (MSCs) and cardiosphere-derived cells (CDCs): Pilot validation in porcine ischemia-reperfusion model. Biomaterials. 74: 19-30. PMID 26433489 DOI: 10.1016/j.biomaterials.2015.09.026  1
2015 Chitgupi U, Zhang Y, Lo CY, Shao S, Song W, Geng J, Neelamegham S, Lovell JF. Sulfonated Polyethylenimine for Photosensitizer Conjugation and Targeting. Bioconjugate Chemistry. 26: 1633-9. PMID 26057017 DOI: 10.1021/acs.bioconjchem.5b00241  0.64
2015 Gogia S, Lo CY, Neelamegham S. Detection of Plasma Protease Activity Using Microsphere-Cytometry Assays with E. coli Derived Substrates: VWF Proteolysis by ADAMTS13. Plos One. 10: e0126556. PMID 25992814 DOI: 10.1371/journal.pone.0126556  0.64
2015 Shao S, Geng J, Ah Yi H, Gogia S, Neelamegham S, Jacobs A, Lovell JF. Functionalization of cobalt porphyrin-phospholipid bilayers with his-tagged ligands and antigens. Nature Chemistry. 7: 438-46. PMID 25901823 DOI: 10.1038/nchem.2236  1
2015 Liu G, Neelamegham S. Integration of systems glycobiology with bioinformatics toolboxes, glycoinformatics resources, and glycoproteomics data. Wiley Interdisciplinary Reviews. Systems Biology and Medicine. 7: 163-81. PMID 25871730 DOI: 10.1002/wsbm.1296  1
2015 Mondal N, Buffone A, Stolfa G, Antonopoulos A, Lau JT, Haslam SM, Dell A, Neelamegham S. ST3Gal-4 is the primary sialyltransferase regulating the synthesis of E-, P-, and L-selectin ligands on human myeloid leukocytes. Blood. 125: 687-96. PMID 25498912 DOI: 10.1182/blood-2014-07-588590  1
2015 Gogia S, Lo CY, Neelamegham S. Detection of plasma protease activity using microsphere-cytometry assays with E. coli derived substrates: VWF proteolysis by ADAMTS13 Plos One. 10. DOI: 10.1371/journal.pone.0126556  1
2015 Chitgupi U, Zhang Y, Lo CY, Shao S, Song W, Geng J, Neelamegham S, Lovell JF. Sulfonated Polyethylenimine for Photosensitizer Conjugation and Targeting Bioconjugate Chemistry. 26: 1633-1639. DOI: 10.1021/acs.bioconjchem.5b00241  1
2014 Madabhushi SR, Zhang C, Kelkar A, Dayananda KM, Neelamegham S. Platelet GpIba binding to von Willebrand Factor under fluid shear:contributions of the D′D3-domain, A1-domain flanking peptide and O-linked glycans. Journal of the American Heart Association. 3: e001420. PMID 25341886 DOI: 10.1161/JAHA.114.001420  1
2014 Patil SA, Bshara W, Morrison C, Chandrasekaran EV, Matta KL, Neelamegham S. Overexpression of α2,3sialyl T-antigen in breast cancer determined by miniaturized glycosyltransferase assays and confirmed using tissue microarray immunohistochemical analysis. Glycoconjugate Journal. 31: 509-21. PMID 25142811 DOI: 10.1007/s10719-014-9548-4  1
2014 Liu G, Neelamegham S. A computational framework for the automated construction of glycosylation reaction networks. Plos One. 9: e100939. PMID 24978019 DOI: 10.1371/journal.pone.0100939  1
2013 Lo CY, Antonopoulos A, Dell A, Haslam SM, Lee T, Neelamegham S. The use of surface immobilization of P-selectin glycoprotein ligand-1 on mesenchymal stem cells to facilitate selectin mediated cell tethering and rolling. Biomaterials. 34: 8213-22. PMID 23891082 DOI: 10.1016/j.biomaterials.2013.07.033  1
2013 Mondal N, Buffone A, Neelamegham S. Distinct glycosyltransferases synthesize E-selectin ligands in human vs. mouse leukocytes. Cell Adhesion & Migration. 7: 288-92. PMID 23590904 DOI: 10.4161/cam.24714  1
2013 Lo CY, Antonopoulos A, Gupta R, Qu J, Dell A, Haslam SM, Neelamegham S. Competition between core-2 GlcNAc-transferase and ST6GalNAc-transferase regulates the synthesis of the leukocyte selectin ligand on human P-selectin glycoprotein ligand-1. The Journal of Biological Chemistry. 288: 13974-87. PMID 23548905 DOI: 10.1074/jbc.M113.463653  1
2013 Liu G, Puri A, Neelamegham S. Glycosylation Network Analysis Toolbox: a MATLAB-based environment for systems glycobiology. Bioinformatics (Oxford, England). 29: 404-6. PMID 23230149 DOI: 10.1093/bioinformatics/bts703  1
2013 Buffone A, Mondal N, Gupta R, McHugh KP, Lau JT, Neelamegham S. Silencing α1,3-fucosyltransferases in human leukocytes reveals a role for FUT9 enzyme during E-selectin-mediated cell adhesion. The Journal of Biological Chemistry. 288: 1620-33. PMID 23192350 DOI: 10.1074/jbc.M112.400929  1
2013 Madabhushi SR, Neelamegham S. Mechanisms of platelet activation by biomaterials and fluid shear flow Ceramic Transactions. 242: 113-123.  1
2012 Neelamegham S. The computing platelet: integrating environmental cues. Blood. 120: 3-4. PMID 22767574 DOI: 10.1182/blood-2012-05-426007  1
2012 Madabhushi SR, Shang C, Dayananda KM, Rittenhouse-Olson K, Murphy M, Ryan TE, Montgomery RR, Neelamegham S. von Willebrand factor (VWF) propeptide binding to VWF D'D3 domain attenuates platelet activation and adhesion. Blood. 119: 4769-78. PMID 22452980 DOI: 10.1182/blood-2011-10-387548  1
2012 Patil SA, Chandrasekaran EV, Matta KL, Parikh A, Tzanakakis ES, Neelamegham S. Scaling down the size and increasing the throughput of glycosyltransferase assays: activity changes on stem cell differentiation. Analytical Biochemistry. 425: 135-44. PMID 22449497 DOI: 10.1016/j.ab.2012.03.009  1
2012 Chandrasekaran EV, Xue J, Xia J, Locke RD, Patil SA, Neelamegham S, Matta KL. Characterization of cancer associated mucin type O-glycans using the exchange sialylation properties of mammalian sialyltransferase ST3Gal-II. Journal of Proteome Research. 11: 2609-18. PMID 22329400 DOI: 10.1021/pr201108q  1
2012 Chinthamani S, Odusanwo O, Mondal N, Nelson J, Neelamegham S, Baker OJ. Lipoxin A4 inhibits immune cell binding to salivary epithelium and vascular endothelium. American Journal of Physiology. Cell Physiology. 302: C968-78. PMID 22205391 DOI: 10.1152/ajpcell.00259.2011  1
2012 Puri A, Neelamegham S. Understanding glycomechanics using mathematical modeling: a review of current approaches to simulate cellular glycosylation reaction networks. Annals of Biomedical Engineering. 40: 816-27. PMID 22090146 DOI: 10.1007/s10439-011-0464-5  1
2012 Simon SI, Neelamegham S, Konstantopoulos K. Preface to special issue: "Glycomechanics: Sugar coating blood cell-endothelial interactions in shear flow" Annals of Biomedical Engineering. 40: 764-765. DOI: 10.1007/s10439-012-0533-4  1
2011 Chandrasekaran EV, Xue J, Xia J, Locke RD, Patil SA, Neelamegham S, Matta KL. Mammalian sialyltransferase ST3Gal-II: its exchange sialylation catalytic properties allow labeling of sialyl residues in mucin-type sialylated glycoproteins and specific gangliosides. Biochemistry. 50: 9475-87. PMID 21913655 DOI: 10.1021/bi200301w  1
2011 Barthel SR, Antonopoulos A, Cedeno-Laurent F, Schaffer L, Hernandez G, Patil SA, North SJ, Dell A, Matta KL, Neelamegham S, Haslam SM, Dimitroff CJ. Peracetylated 4-fluoro-glucosamine reduces the content and repertoire of N- and O-glycans without direct incorporation. The Journal of Biological Chemistry. 286: 21717-31. PMID 21493714 DOI: 10.1074/jbc.M110.194597  1
2011 Neelamegham S, Liu G. Systems glycobiology: biochemical reaction networks regulating glycan structure and function. Glycobiology. 21: 1541-53. PMID 21436236 DOI: 10.1093/glycob/cwr036  1
2011 Dayananda KM, Gogia S, Neelamegham S. Escherichia coli-derived von Willebrand factor-A2 domain fluorescence/Förster resonance energy transfer proteins that quantify ADAMTS13 activity. Analytical Biochemistry. 410: 206-13. PMID 21146487 DOI: 10.1016/j.ab.2010.12.005  1
2010 Dayananda KM, Singh I, Mondal N, Neelamegham S. von Willebrand factor self-association on platelet GpIbalpha under hydrodynamic shear: effect on shear-induced platelet activation. Blood. 116: 3990-8. PMID 20696943 DOI: 10.1182/blood-2010-02-269266  1
2010 Lim KH, Madabhushi SR, Mann J, Neelamegham S, Park S. Disulfide trapping of protein complexes on the yeast surface. Biotechnology and Bioengineering. 106: 27-41. PMID 20047188 DOI: 10.1002/bit.22651  1
2010 Marathe DD, Buffone A, Chandrasekaran EV, Xue J, Locke RD, Nasirikenari M, Lau JT, Matta KL, Neelamegham S. Fluorinated per-acetylated GalNAc metabolically alters glycan structures on leukocyte PSGL-1 and reduces cell binding to selectins. Blood. 115: 1303-12. PMID 19996411 DOI: 10.1182/blood-2009-07-231480  1
2009 Themistou E, Singh I, Shang C, Balu-Iyer SV, Alexandridis P, Neelamegham S. Application of fluorescence spectroscopy to quantify shear-induced protein conformation change. Biophysical Journal. 97: 2567-76. PMID 19883600 DOI: 10.1016/j.bpj.2009.08.023  1
2009 Jayakumar D, Marathe DD, Neelamegham S. Detection of site-specific glycosylation in proteins using flow cytometry. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 75: 866-73. PMID 19735085 DOI: 10.1002/cyto.a.20773  1
2009 Singh I, Themistou E, Porcar L, Neelamegham S. Fluid shear induces conformation change in human blood protein von Willebrand factor in solution. Biophysical Journal. 96: 2313-20. PMID 19289057 DOI: 10.1016/j.bpj.2008.12.3900  1
2008 Liu G, Marathe DD, Matta KL, Neelamegham S. Systems-level modeling of cellular glycosylation reaction networks: O-linked glycan formation on natural selectin ligands. Bioinformatics (Oxford, England). 24: 2740-7. PMID 18842604 DOI: 10.1093/bioinformatics/btn515  1
2008 Marathe DD, Chandrasekaran EV, Lau JT, Matta KL, Neelamegham S. Systems-level studies of glycosyltransferase gene expression and enzyme activity that are associated with the selectin binding function of human leukocytes. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 22: 4154-67. PMID 18716032 DOI: 10.1096/fj.07-104257  1
2008 Xiao Z, Visentin GP, Dayananda KM, Neelamegham S. Immune complexes formed following the binding of anti-platelet factor 4 (CXCL4) antibodies to CXCL4 stimulate human neutrophil activation and cell adhesion. Blood. 112: 1091-100. PMID 18539895 DOI: 10.1182/blood-2008-04-153288  1
2008 Diamond SL, Lawrence MB, Neelamegham S. Harry L. Goldsmith, Ph.d. Annals of Biomedical Engineering. 36: 523-6. PMID 18330702 DOI: 10.1007/s10439-008-9479-y  1
2008 Zhang Y, Hayenga HN, Sarantos MR, Simon SI, Neelamegham S. Differential regulation of neutrophil CD18 integrin function by di- and tri-valent cations: manganese vs. gadolinium. Annals of Biomedical Engineering. 36: 647-60. PMID 18317931 DOI: 10.1007/s10439-008-9446-7  1
2008 Liu G, Neelamegham S. In silico Biochemical Reaction Network Analysis (IBRENA): a package for simulation and analysis of reaction networks. Bioinformatics (Oxford, England). 24: 1109-11. PMID 18310056 DOI: 10.1093/bioinformatics/btn061  1
2008 Chandrasekaran EV, Xue J, Xia J, Locke RD, Matta KL, Neelamegham S. Reversible sialylation: synthesis of cytidine 5'-monophospho-N-acetylneuraminic acid from cytidine 5'-monophosphate with alpha2,3-sialyl O-glycan-, glycolipid-, and macromolecule-based donors yields diverse sialylated products. Biochemistry. 47: 320-30. PMID 18067323 DOI: 10.1021/bi701472g  1
2008 Themistou E, Alexandridis P, Neelamegham S. Studies at the interface of materials science and bioengineering: New tools to assess conformational changes in protein solution structure Aiche Annual Meeting, Conference Proceedings 1
2008 Patil SA, Marathe DD, Chandrasekaran EV, Matta K, Neelamegham S. Glycosyltransferase assays for leukocytes, cancer cells and stem cells Aiche Annual Meeting, Conference Proceedings 1
2008 Themistou E, Singh I, Balu-Iyer SV, Alexandridis P, Neelamegham S. Shear-induced structural changes in blood proteins Aiche Annual Meeting, Conference Proceedings 1
2006 Beauharnois ME, Neelamegham S, Matta KL. Quantitative measurement of selectin-ligand interactions: assays to identify a sweet pill in a library of carbohydrates. Methods in Molecular Biology (Clifton, N.J.). 347: 343-58. PMID 17072022 DOI: 10.1385/1-59745-167-3:343  1
2006 Singh I, Shankaran H, Beauharnois ME, Xiao Z, Alexandridis P, Neelamegham S. Solution structure of human von Willebrand factor studied using small angle neutron scattering. The Journal of Biological Chemistry. 281: 38266-75. PMID 17052980 DOI: 10.1074/jbc.M607123200  1
2006 Chandrasekaran EV, Xue J, Neelamegham S, Matta KL. The pattern of glycosyl- and sulfotransferase activities in cancer cell lines: a predictor of individual cancer-associated distinct carbohydrate structures for the structural identification of signature glycans. Carbohydrate Research. 341: 983-94. PMID 16545347 DOI: 10.1016/j.carres.2006.02.017  1
2006 Xiao Z, Goldsmith HL, McIntosh FA, Shankaran H, Neelamegham S. Biomechanics of P-selectin PSGL-1 bonds: shear threshold and integrin-independent cell adhesion. Biophysical Journal. 90: 2221-34. PMID 16387772 DOI: 10.1529/biophysj.105.065789  1
2005 Chandrasekaran EV, Xue J, Xia J, Chawda R, Piskorz C, Locke RD, Neelamegham S, Matta KL. Analysis of the specificity of sialyltransferases toward mucin core 2, globo, and related structures. identification of the sialylation sequence and the effects of sulfate, fucose, methyl, and fluoro substituents of the carbohydrate chain in the biosynthesis of selectin and siglec ligands, and novel sialylation by cloned alpha2,3(O)sialyltransferase. Biochemistry. 44: 15619-35. PMID 16300412 DOI: 10.1021/bi050246m  1
2005 Beauharnois ME, Lindquist KC, Marathe D, Vanderslice P, Xia J, Matta KL, Neelamegham S. Affinity and kinetics of sialyl Lewis-X and core-2 based oligosaccharides binding to L- and P-selectin. Biochemistry. 44: 9507-19. PMID 15996105 DOI: 10.1021/bi0507130  1
2005 Liu G, Swihart MT, Neelamegham S. Sensitivity, principal component and flux analysis applied to signal transduction: the case of epidermal growth factor mediated signaling. Bioinformatics (Oxford, England). 21: 1194-202. PMID 15531606 DOI: 10.1093/bioinformatics/bti118  1
2004 Neelamegham S. Transport features, reaction kinetics and receptor biomechanics controlling selectin and integrin mediated cell adhesion. Cell Communication & Adhesion. 11: 35-50. PMID 15500296 DOI: 10.1080/15419060490471793  1
2004 McDonough DB, McIntosh FA, Spanos C, Neelamegham S, Goldsmith HL, Simon SI. Cooperativity between selectins and beta2-integrins define neutrophil capture and stable adhesion in shear flow. Annals of Biomedical Engineering. 32: 1179-92. PMID 15493506 DOI: 10.1114/B:ABME.0000039352.11428.9d  1
2004 Chandrasekaran EV, Lakhaman SS, Chawda R, Piskorz CF, Neelamegham S, Matta KL. Identification of physiologically relevant substrates for cloned Gal: 3-O-sulfotransferases (Gal3STs): distinct high affinity of Gal3ST-2 and LS180 sulfotransferase for the globo H backbone, Gal3ST-3 for N-glycan multiterminal Galbeta1, 4GlcNAcbeta units and 6-sulfoGalbeta1, 4GlcNAcbeta, and Gal3ST-4 for the mucin core-2 trisaccharide. The Journal of Biological Chemistry. 279: 10032-41. PMID 14701868 DOI: 10.1074/jbc.M311989200  1
2004 Shankaran H, Neelamegham S. Hydrodynamic forces applied on intercellular bonds, soluble molecules, and cell-surface receptors. Biophysical Journal. 86: 576-88. PMID 14695302 DOI: 10.1016/S0006-3495(04)74136-3  1
2003 Zhang Y, Neelamegham S. PPLATE: a computer program for analysis of parallel-plate flow chamber experimental data. Journal of Immunological Methods. 278: 319-21. PMID 12957418 DOI: 10.1016/S0022-1759(03)00194-7  1
2003 Zhang Y, Neelamegham S. An analysis tool to quantify the efficiency of cell tethering and firm-adhesion in the parallel-plate flow chamber. Journal of Immunological Methods. 278: 305-17. PMID 12957417 DOI: 10.1016/S0022-1759(03)00082-6  1
2003 King MR, Hammer DA. Hydrodynamic recruitment of rolling leukocytes in vitro. Biophysical Journal. 84: 4182; author reply 4. PMID 12770920 DOI: 10.1016/S0006-3495(03)75142-X  1
2003 Shankaran H, Alexandridis P, Neelamegham S. Aspects of hydrodynamic shear regulating shear-induced platelet activation and self-association of von Willebrand factor in suspension. Blood. 101: 2637-45. PMID 12456504 DOI: 10.1182/blood-2002-05-1550  1
2002 Zhang Y, Neelamegham S. Estimating the efficiency of cell capture and arrest in flow chambers: study of neutrophil binding via E-selectin and ICAM-1. Biophysical Journal. 83: 1934-52. PMID 12324413 DOI: 10.1016/S0006-3495(02)73956-8  1
2002 Neelamegham S, Matta KL. Liposomes containing ligands. Binding specificity to selectins. Methods in Molecular Biology (Clifton, N.J.). 199: 175-91. PMID 12094569 DOI: 10.1385/1-59259-175-2:175  1
2002 Zhang Y, Neelamegham S. Estimation of cell capture and arrest efficiency in flow chambers Annual International Conference of the Ieee Engineering in Medicine and Biology - Proceedings. 2: 907-908.  1
2002 Shankaran H, Alexandridis P, Neelamegham S. Hydrodynamic forces regulate platelet activation and self-association of vWF in suspension Annual International Conference of the Ieee Engineering in Medicine and Biology - Proceedings. 2: 905-906.  1
2002 Shankaran H, Zhou Y, Neelamegham S. Dynamics of type IIb mutation-induced conformational changes in the von Willebrand factor A1 domain Annual International Conference of the Ieee Engineering in Medicine and Biology - Proceedings. 1: 672-673.  1
2002 Beauharnois M, Matta K, Singh S, Neelamegham S. Affinity and kinetic analysis of L-selectin binding to their natural ligands and to synthetic oligosaccharides Annual International Conference of the Ieee Engineering in Medicine and Biology - Proceedings. 1: 670-671.  1
2001 Ahmed F, Alexandridis P, Shankaran H, Neelamegham S. The ability of poloxamers to inhibit platelet aggregation depends on their physicochemical properties. Thrombosis and Haemostasis. 86: 1532-9. PMID 11776324  1
2001 Shankaran H, Neelamegham S. Effect of secondary flow on biological experiments in the cone-plate viscometer: methods for estimating collision frequency, wall shear stress and inter-particle interactions in non-linear flow. Biorheology. 38: 275-304. PMID 11673645  1
2001 Shankaran H, Neelamegham S. Nonlinear flow affects hydrodynamic forces and neutrophil adhesion rates in cone-plate viscometers. Biophysical Journal. 80: 2631-48. PMID 11371440 DOI: 10.1016/S0006-3495(01)76233-9  1
2001 Ahmed F, Alexandridis P, Neelamegham S. Synthesis and application of fluorescein-labeled pluronic block copolymers to the study of polymer-surface interactions Langmuir. 17: 537-546. DOI: 10.1021/la001305u  1
2000 Neelamegham S, Taylor AD, Shankaran H, Smith CW, Simon SI. Shear and time-dependent changes in Mac-1, LFA-1, and ICAM-3 binding regulate neutrophil homotypic adhesion. Journal of Immunology (Baltimore, Md. : 1950). 164: 3798-805. PMID 10725740  1
2000 Hentzen ER, Neelamegham S, Kansas GS, Benanti JA, McIntire LV, Smith CW, Simon SI. Sequential binding of CD11a/CD18 and CD11b/CD18 defines neutrophil capture and stable adhesion to intercellular adhesion molecule-1 Blood. 95: 911-920. PMID 10648403  1
1998 Lynam E, Sklar LA, Taylor AD, Neelamegham S, Edwards BS, Smith CW, Simon SI. Beta2-integrins mediate stable adhesion in collisional interactions between neutrophils and ICAM-1-expressing cells. Journal of Leukocyte Biology. 64: 622-30. PMID 9823767  1
1998 Simon SI, Neelamegham S, Taylor A, Smith CW. The multistep process of homotypic neutrophil aggregation: A review of the molecules and effects of hydrodynamics Cell Adhesion and Communication. 6: 263-276. PMID 9823477  1
1998 Konstantopoulos K, Neelamegham S, Burns AR, Hentzen E, Kansas GS, Snapp KR, Berg EL, Hellums JD, Smith CW, McIntire LV, Simon SI. Venous levels of shear support neutrophil-platelet adhesion and neutrophil aggregation in blood via P-selectin and β2-integrin Circulation. 98: 873-882. PMID 9738642  1
1998 Neelamegham S, Taylor AD, Burns AR, Smith CW, Simon SI. Hydrodynamic shear shows distinct roles for LFA-1 and Mac-1 in neutrophil adhesion to intercellular adhesion molecule-1. Blood. 92: 1626-38. PMID 9716590  1
1997 Tsang YTM, Neelamegham S, Hu Y, Berg EL, Burns AR, Smith CW, Simon SI. Synergy between L-Selectin Signaling and Chemotactic Activation during Neutrophil Adhesion and Transmigration Journal of Immunology. 159: 4566-4577. PMID 9379058  1
1997 McIntyre BW, Woodside DG, Caruso DA, Wooten DK, Simon SI, Neelamegham S, Revelle JK, Vanderslice P. Regulation of Human T Lymphocyte Coactivation with an α4 Integrin Antagonist Peptide Journal of Immunology. 158: 4180-4186. PMID 9126978  1
1997 Neelamegham S, Zygourakis K. A quantitative assay for intercellular aggregation Annals of Biomedical Engineering. 25: 180-187. PMID 9124732  1
1997 Neelamegham S, Taylor AD, Hellums JD, Dembo M, Smith CW, Simon SI. Modeling the reversible kinetics of neutrophil aggregation under hydrodynamic shear. Biophysical Journal. 72: 1527-40. PMID 9083659 DOI: 10.1016/S0006-3495(97)78801-5  1
1997 Neelamegham S, Munn LL, Zygourakis K. A model for the kinetics of homotypic cellular aggregation under static conditions Biophysical Journal. 72: 51-64. PMID 8994592  1
1997 Simon SI, Taylor A, Neelamegham S, Hellums JD, Smith CW. Neutrophil aggregation mediated by β2-integrin and ICAM-3 at low hydrodynamic shear Faseb Journal. 11.  1
1996 Taylor AD, Neelamegham S, Hellums JD, Smith CW, Simon SI. Molecular dynamics of the transition from L-selectin- to beta 2-integrin-dependent neutrophil adhesion under defined hydrodynamic shear. Biophysical Journal. 71: 3488-500. PMID 8968618 DOI: 10.1016/S0006-3495(96)79544-9  1
1996 Neelamegham S, Simon SI, McIntyre BW, Zygourakis K. Induction of homotypic lymphocyte aggregation: Evidence for a novel activation state of the β1 integrin Journal of Leukocyte Biology. 59: 872-882. PMID 8691073  1
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