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Noah Zaitlen, Ph.D. - Publications

2009 Bioinformatics University of California, San Diego, La Jolla, CA 
Bioinformatics Biology, Genetics, Computer Science

65 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Galinsky KJ, Reshef YA, Finucane HK, Loh PR, Zaitlen N, Patterson NJ, Brown BC, Price AL. Estimating cross-population genetic correlations of causal effect sizes. Genetic Epidemiology. PMID 30474154 DOI: 10.1002/gepi.22173  0.32
2018 Kang EY, Lee CH, Furlotte NA, Joo JWJ, Kostem E, Zaitlen N, Eskin E, Han B. An Association Mapping Framework To Account for Potential Sex Difference in Genetic Architectures. Genetics. PMID 29752291 DOI: 10.1534/genetics.117.300501  1
2018 Mangul S, Yang HT, Strauli N, Gruhl F, Porath HT, Hsieh K, Chen L, Daley T, Christenson S, Wesolowska-Andersen A, Spreafico R, Rios C, Eng C, Smith AD, Hernandez RD, ... ... Zaitlen N, et al. ROP: dumpster diving in RNA-sequencing to find the source of 1 trillion reads across diverse adult human tissues. Genome Biology. 19: 36. PMID 29548336 DOI: 10.1186/s13059-018-1403-7  1
2017 Kang HM, Subramaniam M, Targ S, Nguyen M, Maliskova L, McCarthy E, Wan E, Wong S, Byrnes L, Lanata CM, Gate RE, Mostafavi S, Marson A, Zaitlen N, Criswell LA, et al. Multiplexed droplet single-cell RNA-sequencing using natural genetic variation. Nature Biotechnology. PMID 29227470 DOI: 10.1038/nbt.4042  0.76
2017 Park DS, Eskin I, Kang EY, Gamazon ER, Eng C, Gignoux CR, Galanter JM, Burchard E, Ye CJ, Aschard H, Eskin E, Halperin E, Zaitlen N. An ancestry-based approach for detecting interactions. Genetic Epidemiology. PMID 29114909 DOI: 10.1002/gepi.22087  1
2017 Aschard H, Guillemot V, Vilhjalmsson B, Patel CJ, Skurnik D, Ye CJ, Wolpin B, Kraft P, Zaitlen N. Covariate selection for association screening in multiphenotype genetic studies. Nature Genetics. PMID 29038595 DOI: 10.1038/ng.3975  0.32
2017 Rahmani E, Zaitlen N, Baran Y, Eng C, Hu D, Galanter J, Oh S, Burchard EG, Eskin E, Zou J, Halperin E. Correcting for cell-type heterogeneity in DNA methylation: a comprehensive evaluation. Nature Methods. 14: 218-219. PMID 28245214 DOI: 10.1038/nmeth.4190  1
2017 Rahmani E, Yedidim R, Shenhav L, Schweiger R, Weissbrod O, Zaitlen N, Halperin E. GLINT: a user-friendly toolset for the analysis of high-throughput DNA-methylation array data. Bioinformatics (Oxford, England). PMID 28177067 DOI: 10.1093/bioinformatics/btx059  0.6
2017 Rahmani E, Shenhav L, Schweiger R, Yousefi P, Huen K, Eskenazi B, Eng C, Huntsman S, Hu D, Galanter J, Oh SS, Waldenberger M, Strauch K, Grallert H, Meitinger T, ... ... Zaitlen N, et al. Genome-wide methylation data mirror ancestry information. Epigenetics & Chromatin. 10: 1. PMID 28149326 DOI: 10.1186/s13072-016-0108-y  0.6
2017 Galanter JM, Gignoux CR, Oh SS, Torgerson D, Pino-Yanes M, Thakur N, Eng C, Hu D, Huntsman S, Farber HJ, Avila PC, Brigino-Buenaventura E, LeNoir MA, Meade K, Serebrisky D, ... ... Zaitlen N, et al. Differential methylation between ethnic sub-groups reflects the effect of genetic ancestry and environmental exposures. Elife. 6. PMID 28044981 DOI: 10.7554/eLife.20532  0.32
2016 Hayeck TJ, Loh PR, Pollack S, Gusev A, Patterson N, Zaitlen NA, Price AL. Mixed Model Association with Family-Biased Case-Control Ascertainment. American Journal of Human Genetics. PMID 28017371 DOI: 10.1016/j.ajhg.2016.11.015  0.32
2016 Zaitlen N, Huntsman S, Hu D, Spear M, Eng C, Oh SS, White MJ, Mak A, Davis A, Meade K, Brigino-Buenaventura E, LeNoir MA, Bibbins-Domingo K, Burchard EG, Halperin E. The Effects of Migration and Assortative Mating on Admixture Linkage Disequilibrium. Genetics. PMID 27879348 DOI: 10.1534/genetics.116.192138  0.6
2016 Brown BC, Ye CJ, Price AL, Zaitlen N. Transethnic Genetic-Correlation Estimates from Summary Statistics. American Journal of Human Genetics. PMID 27321947 DOI: 10.1016/j.ajhg.2016.05.001  1
2016 Uricchio LH, Zaitlen NA, Ye CJ, Witte JS, Hernandez RD. Selection and explosive growth alter genetic architecture and hamper the detection of causal rare variants. Genome Research. PMID 27197206 DOI: 10.1101/gr.202440.115  1
2016 Brown BC, Price AL, Patsopoulos NA, Zaitlen N. Local Joint Testing Improves Power and Identifies Hidden Heritability in Association Studies. Genetics. PMID 27182951 DOI: 10.1534/genetics.116.188292  1
2016 Rahmani E, Zaitlen N, Baran Y, Eng C, Hu D, Galanter J, Oh S, Burchard EG, Eskin E, Zou J, Halperin E. Sparse PCA corrects for cell type heterogeneity in epigenome-wide association studies. Nature Methods. PMID 27018579 DOI: 10.1038/nmeth.3809  1
2016 Mefford JA, Zaitlen NA, Witte JS. Comment: A Human Genetics Perspective Journal of the American Statistical Association. 111: 124-127. DOI: 10.1080/01621459.2016.1149404  1
2015 Zou JY, Park DS, Burchard EG, Torgerson DG, Pino-Yanes M, Song YS, Sankararaman S, Halperin E, Zaitlen N. Genetic and socioeconomic study of mate choice in Latinos reveals novel assortment patterns. Proceedings of the National Academy of Sciences of the United States of America. 112: 13621-6. PMID 26483472 DOI: 10.1073/pnas.1501741112  1
2015 Caswell JL, Camarda R, Zhou AY, Huntsman S, Hu D, Brenner SE, Zaitlen N, Goga A, Ziv E. Multiple breast cancer risk variants are associated with differential transcript isoform expression in tumors. Human Molecular Genetics. PMID 26472073 DOI: 10.1093/hmg/ddv432  1
2015 Park DS, Brown B, Eng C, Huntsman S, Hu D, Torgerson DG, Burchard EG, Zaitlen N. Adapt-Mix: learning local genetic correlation structure improves summary statistics-based analyses. Bioinformatics (Oxford, England). 31: i181-i189. PMID 26072481 DOI: 10.1093/bioinformatics/btv230  1
2015 Baran Y, Subramaniam M, Biton A, Tukiainen T, Tsang EK, Rivas MA, Pirinen M, Gutierrez-Arcelus M, Smith KS, Kukurba KR, Zhang R, Eng C, Torgerson DG, Urbanek C, ... ... Zaitlen NA, et al. The landscape of genomic imprinting across diverse adult human tissues. Genome Research. 25: 927-36. PMID 25953952 DOI: 10.1101/gr.192278.115  1
2015 Watkin LB, Jessen B, Wiszniewski W, Vece TJ, Jan M, Sha Y, Thamsen M, Santos-Cortez RL, Lee K, Gambin T, Forbes LR, Law CS, Stray-Pedersen A, Cheng MH, Mace EM, ... ... Zaitlen N, et al. COPA mutations impair ER-Golgi transport and cause hereditary autoimmune-mediated lung disease and arthritis. Nature Genetics. 47: 654-60. PMID 25894502 DOI: 10.1038/ng.3279  1
2015 Hayeck TJ, Zaitlen NA, Loh PR, Vilhjalmsson B, Pollack S, Gusev A, Yang J, Chen GB, Goddard ME, Visscher PM, Patterson N, Price AL. Mixed model with correction for case-control ascertainment increases association power. American Journal of Human Genetics. 96: 720-30. PMID 25892111 DOI: 10.1016/j.ajhg.2015.03.004  1
2015 Park DS, Baran Y, Hormozdiari F, Eng C, Torgerson DG, Burchard EG, Zaitlen N. PIGS: improved estimates of identity-by-descent probabilities by probabilistic IBD graph sampling. Bmc Bioinformatics. 16: S9. PMID 25860540 DOI: 10.1186/1471-2105-16-S5-S9  1
2015 Pirinen M, Lappalainen T, Zaitlen NA, Dermitzakis ET, Donnelly P, McCarthy MI, Rivas MA. Assessing allele-specific expression across multiple tissues from RNA-seq read data. Bioinformatics (Oxford, England). PMID 25819081 DOI: 10.1093/bioinformatics/btv074  1
2015 Cornelis MC, Zaitlen N, Hu FB, Kraft P, Price AL. Genetic and environmental components of family history in type 2 diabetes. Human Genetics. 134: 259-67. PMID 25543539 DOI: 10.1007/s00439-014-1519-0  1
2015 Aschard H, Zaitlen N, Lindström S, Kraft P. Variation in predictive ability of common genetic variants by established strata: the example of breast cancer and age. Epidemiology (Cambridge, Mass.). 26: 51-8. PMID 25380502 DOI: 10.1097/EDE.0000000000000195  1
2014 Zaitlen N, Pasaniuc B, Sankararaman S, Bhatia G, Zhang J, Gusev A, Young T, Tandon A, Pollack S, Vilhjálmsson BJ, Assimes TL, Berndt SI, Blot WJ, Chanock S, Franceschini N, et al. Leveraging population admixture to characterize the heritability of complex traits. Nature Genetics. 46: 1356-62. PMID 25383972 DOI: 10.1038/ng.3139  1
2014 Ye CJ, Feng T, Kwon HK, Raj T, Wilson MT, Asinovski N, McCabe C, Lee MH, Frohlich I, Paik HI, Zaitlen N, Hacohen N, Stranger B, De Jager P, Mathis D, et al. Intersection of population variation and autoimmunity genetics in human T cell activation. Science (New York, N.Y.). 345: 1254665. PMID 25214635 DOI: 10.1126/science.1254665  1
2014 Pasaniuc B, Zaitlen N, Shi H, Bhatia G, Gusev A, Pickrell J, Hirschhorn J, Strachan DP, Patterson N, Price AL. Fast and accurate imputation of summary statistics enhances evidence of functional enrichment. Bioinformatics (Oxford, England). 30: 2906-14. PMID 24990607 DOI: 10.1093/bioinformatics/btu416  1
2014 Zhao W, Pollack JL, Blagev DP, Zaitlen N, McManus MT, Erle DJ. Massively parallel functional annotation of 3' untranslated regions. Nature Biotechnology. 32: 387-91. PMID 24633241 DOI: 10.1038/nbt.2851  1
2014 Yang J, Zaitlen NA, Goddard ME, Visscher PM, Price AL. Advantages and pitfalls in the application of mixed-model association methods. Nature Genetics. 46: 100-6. PMID 24473328 DOI: 10.1038/ng.2876  1
2014 Chimusa ER, Zaitlen N, Daya M, Möller M, van Helden PD, Mulder NJ, Price AL, Hoal EG. Genome-wide association study of ancestry-specific TB risk in the South African Coloured population. Human Molecular Genetics. 23: 796-809. PMID 24057671 DOI: 10.1093/hmg/ddt462  1
2013 Gusev A, Bhatia G, Zaitlen N, Vilhjalmsson BJ, Diogo D, Stahl EA, Gregersen PK, Worthington J, Klareskog L, Raychaudhuri S, Plenge RM, Pasaniuc B, Price AL. Quantifying missing heritability at known GWAS loci. Plos Genetics. 9: e1003993. PMID 24385918 DOI: 10.1371/journal.pgen.1003993  1
2013 Zaitlen N, Kraft P, Patterson N, Pasaniuc B, Bhatia G, Pollack S, Price AL. Using extended genealogy to estimate components of heritability for 23 quantitative and dichotomous traits. Plos Genetics. 9: e1003520. PMID 23737753 DOI: 10.1371/journal.pgen.1003520  1
2013 Pasaniuc B, Sankararaman S, Torgerson DG, Gignoux C, Zaitlen N, Eng C, Rodriguez-Cintron W, Chapela R, Ford JG, Avila PC, Rodriguez-Santana J, Chen GK, Le Marchand L, Henderson B, Reich D, et al. Analysis of Latino populations from GALA and MEC studies reveals genomic loci with biased local ancestry estimation. Bioinformatics (Oxford, England). 29: 1407-15. PMID 23572411 DOI: 10.1093/bioinformatics/btt166  1
2013 Aschard H, Zaitlen N, Tamimi RM, Lindström S, Kraft P. A nonparametric test to detect quantitative trait loci where the phenotypic distribution differs by genotypes. Genetic Epidemiology. 37: 323-33. PMID 23512279 DOI: 10.1002/gepi.21716  1
2013 Price AL, Zaitlen NA, Reich D, Patterson N. Response to Sul and Eskin. Nature Reviews. Genetics. 14: 300. PMID 23438870 DOI: 10.1038/nrg2813-c2  1
2012 Zaitlen N, Lindström S, Pasaniuc B, Cornelis M, Genovese G, Pollack S, Barton A, Bickeböller H, Bowden DW, Eyre S, Freedman BI, Friedman DJ, Field JK, Groop L, Haugen A, et al. Informed conditioning on clinical covariates increases power in case-control association studies. Plos Genetics. 8: e1003032. PMID 23144628 DOI: 10.1371/journal.pgen.1003032  1
2012 Zaitlen N, Kraft P. Heritability in the genome-wide association era. Human Genetics. 131: 1655-64. PMID 22821350 DOI: 10.1007/s00439-012-1199-6  1
2012 Pasaniuc B, Rohland N, McLaren PJ, Garimella K, Zaitlen N, Li H, Gupta N, Neale BM, Daly MJ, Sklar P, Sullivan PF, Bergen S, Moran JL, Hultman CM, Lichtenstein P, et al. Extremely low-coverage sequencing and imputation increases power for genome-wide association studies. Nature Genetics. 44: 631-5. PMID 22610117 DOI: 10.1038/ng.2283  1
2012 Zaitlen N, Pasaniuc B, Patterson N, Pollack S, Voight B, Groop L, Altshuler D, Henderson BE, Kolonel LN, Le Marchand L, Waters K, Haiman CA, Stranger BE, Dermitzakis ET, Kraft P, et al. Analysis of case-control association studies with known risk variants. Bioinformatics (Oxford, England). 28: 1729-37. PMID 22556366 DOI: 10.1093/bioinformatics/bts259  1
2011 Aschard H, Qiu W, Pasaniuc B, Zaitlen N, Cho MH, Carey V. Combining effects from rare and common genetic variants in an exome-wide association study of sequence data. Bmc Proceedings. 5: S44. PMID 22373328 DOI: 10.1186/1753-6561-5-S9-S44  0.6
2011 He D, Zaitlen N, Pasaniuc B, Eskin E, Halperin E. Genotyping common and rare variation using overlapping pool sequencing. Bmc Bioinformatics. 12: S2. PMID 21989232 DOI: 10.1186/1471-2105-12-S6-S2  1
2011 Bhatia G, Patterson N, Pasaniuc B, Zaitlen N, Genovese G, Pollack S, Mallick S, Myers S, Tandon A, Spencer C, Palmer CD, Adeyemo AA, Akylbekova EL, Cupples LA, Divers J, et al. Genome-wide comparison of African-ancestry populations from CARe and other cohorts reveals signals of natural selection. American Journal of Human Genetics. 89: 368-81. PMID 21907010 DOI: 10.1016/j.ajhg.2011.07.025  1
2011 Pasaniuc B, Zaitlen N, Lettre G, Chen GK, Tandon A, Kao WH, Ruczinski I, Fornage M, Siscovick DS, Zhu X, Larkin E, Lange LA, Cupples LA, Yang Q, Akylbekova EL, et al. Enhanced statistical tests for GWAS in admixed populations: assessment using African Americans from CARe and a Breast Cancer Consortium. Plos Genetics. 7: e1001371. PMID 21541012 DOI: 10.1371/journal.pgen.1001371  1
2011 Paşaniuc B, Zaitlen N, Halperin E. Accurate estimation of expression levels of homologous genes in RNA-seq experiments. Journal of Computational Biology : a Journal of Computational Molecular Cell Biology. 18: 459-68. PMID 21385047 DOI: 10.1089/cmb.2010.0259  1
2010 Zaitlen N, Eskin E. Imputation aware meta-analysis of genome-wide association studies. Genetic Epidemiology. 34: 537-42. PMID 20717975 DOI: 10.1002/gepi.20507  1
2010 Santana R, Mendiburu A, Zaitlen N, Eskin E, Lozano JA. Multi-marker tagging single nucleotide polymorphism selection using estimation of distribution algorithms. Artificial Intelligence in Medicine. 50: 193-201. PMID 20650616 DOI: 10.1016/j.artmed.2010.05.010  1
2010 Price AL, Zaitlen NA, Reich D, Patterson N. New approaches to population stratification in genome-wide association studies. Nature Reviews. Genetics. 11: 459-63. PMID 20548291 DOI: 10.1038/nrg2813  1
2010 Kang HM, Zaitlen NA, Eskin E. EMINIM: an adaptive and memory-efficient algorithm for genotype imputation. Journal of Computational Biology : a Journal of Computational Molecular Cell Biology. 17: 547-60. PMID 20377463 DOI: 10.1089/cmb.2009.0199  1
2010 Kang HM, Sul JH, Service SK, Zaitlen NA, Kong SY, Freimer NB, Sabatti C, Eskin E. Variance component model to account for sample structure in genome-wide association studies. Nature Genetics. 42: 348-54. PMID 20208533 DOI: 10.1038/ng.548  1
2010 Zaitlen N, Paşaniuc B, Gur T, Ziv E, Halperin E. Leveraging genetic variability across populations for the identification of causal variants. American Journal of Human Genetics. 86: 23-33. PMID 20085711 DOI: 10.1016/j.ajhg.2009.11.016  1
2009 Smith EN, Bloss CS, Badner JA, Barrett T, Belmonte PL, Berrettini W, Byerley W, Coryell W, Craig D, Edenberg HJ, Eskin E, Foroud T, Gershon E, Greenwood TA, Hipolito M, ... ... Zaitlen N, et al. Genome-wide association study of bipolar disorder in European American and African American individuals. Molecular Psychiatry. 14: 755-63. PMID 19488044 DOI: 10.1038/mp.2009.43  1
2009 Zaitlen N, Kang HM, Eskin E. Linkage effects and analysis of finite sample errors in the HapMap. Human Heredity. 68: 73-86. PMID 19365134 DOI: 10.1159/000212500  1
2009 Sabatti C, Service SK, Hartikainen AL, Pouta A, Ripatti S, Brodsky J, Jones CG, Zaitlen NA, Varilo T, Kaakinen M, Sovio U, Ruokonen A, Laitinen J, Jakkula E, Coin L, et al. Genome-wide association analysis of metabolic traits in a birth cohort from a founder population. Nature Genetics. 41: 35-46. PMID 19060910 DOI: 10.1038/ng.271  1
2009 Kang HM, Zaitlen NA, Han B, Eskin E. An adaptive and memory efficient algorithm for genotype imputation Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 5541: 482-495. DOI: 10.1007/978-3-642-02008-7_34  1
2008 Zaitlen N, Reyes-Gomez M, Heckerman D, Jojic N. Shift-invariant adaptive double threading: learning MHC II-peptide binding. Journal of Computational Biology : a Journal of Computational Molecular Cell Biology. 15: 927-42. PMID 18771399 DOI: 10.1089/cmb.2007.0183  1
2008 Han B, Kang HM, Seo MS, Zaitlen N, Eskin E. Efficient association study design via power-optimized tag SNP selection Annals of Human Genetics. 72: 834-847. PMID 18702637 DOI: 10.1111/j.1469-1809.2008.00469.x  1
2008 Kang HM, Zaitlen NA, Wade CM, Kirby A, Heckerman D, Daly MJ, Eskin E. Efficient control of population structure in model organism association mapping. Genetics. 178: 1709-23. PMID 18385116 DOI: 10.1534/genetics.107.080101  1
2008 Choi A, Zaitlen N, Han B, Pipatsrisawat K, Darwiche A, Eskin E. Efficient genome wide tagging by reduction to SAT Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 5251: 135-147. DOI: 10.1007/978-3-540-87361-7_12  1
2007 Zaitlen N, Kang HM, Eskin E, Halperin E. Leveraging the HapMap correlation structure in association studies. American Journal of Human Genetics. 80: 683-91. PMID 17357074 DOI: 10.1086/513109  1
2007 O'Rourke S, Zaitlen N, Jojic N, Eskin E. Reconstructing the phylogeny of mobile elements Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 4453: 196-210.  1
2007 Zaitlen N, Reyes-Gomez M, Heckerman D, Jojic N. Shift-invariant adaptive double threading: Learning MHC II - peptide binding Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 4453: 181-195.  1
2005 Zaitlen NA, Kang HM, Feolo ML, Sherry ST, Halperin E, Eskin E. Inference and analysis of haplotypes from combined genotyping studies deposited in dbSNP. Genome Research. 15: 1594-600. PMID 16251470 DOI: 10.1101/gr.4297805  1
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