| Year |
Citation |
Score |
| 2024 |
Dema A, Charafeddine RA, van Haren J, Rahgozar S, Viola G, Jacobs KA, Kutys ML, Wittmann T. Doublecortin reinforces microtubules to promote growth cone advance in soft environments. Biorxiv : the Preprint Server For Biology. PMID 38464100 DOI: 10.1101/2024.02.28.582626 |
0.307 |
|
| 2022 |
Dema A, van Haren J, Wittmann T. Optogenetic EB1 inactivation shortens metaphase spindles by disrupting cortical force-producing interactions with astral microtubules. Current Biology : Cb. PMID 35090591 DOI: 10.1016/j.cub.2022.01.017 |
0.451 |
|
| 2020 |
Zhang J, Velmeshev D, Hashimoto K, Huang YH, Hofmann JW, Shi X, Chen J, Leidal AM, Dishart JG, Cahill MK, Kelley KW, Liddelow SA, Seeley WW, Miller BL, Walther TC, ... ... Wittmann T, et al. Neurotoxic microglia promote TDP-43 proteinopathy in progranulin deficiency. Nature. PMID 32866962 DOI: 10.1038/S41586-020-2709-7 |
0.309 |
|
| 2020 |
Wittmann T, Dema A, van Haren J. Lights, cytoskeleton, action: Optogenetic control of cell dynamics. Current Opinion in Cell Biology. 66: 1-10. PMID 32371345 DOI: 10.1016/J.Ceb.2020.03.003 |
0.422 |
|
| 2020 |
van Haren J, Adachi LS, Wittmann T. Optogenetic Control of Microtubule Dynamics. Methods in Molecular Biology (Clifton, N.J.). 2101: 211-234. PMID 31879907 DOI: 10.1007/978-1-0716-0219-5_14 |
0.436 |
|
| 2019 |
Charafeddine RA, Cortopassi WA, Lak P, Tan R, McKenney RJ, Jacobson MP, Barber DL, Wittmann T. Tau repeat regions contain conserved histidine residues that modulate microtubule-binding in response to changes in pH. The Journal of Biological Chemistry. PMID 30992364 DOI: 10.1074/Jbc.Ra118.007004 |
0.452 |
|
| 2019 |
van Haren J, Wittmann T. Microtubule Plus End Dynamics - Do We Know How Microtubules Grow?: Cells boost microtubule growth by promoting distinct structural transitions at growing microtubule ends. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. e1800194. PMID 30730055 DOI: 10.1002/Bies.201800194 |
0.506 |
|
| 2018 |
van Haren J, Charafeddine RA, Ettinger A, Wang H, Hahn KM, Wittmann T. Local control of intracellular microtubule dynamics by EB1 photodissociation. Nature Cell Biology. PMID 29379139 DOI: 10.1038/S41556-017-0028-5 |
0.503 |
|
| 2018 |
Wittmann T, Haren Jv. Generation of cell lines with light-controlled microtubule dynamics Protocol Exchange. DOI: 10.1038/Protex.2017.155 |
0.371 |
|
| 2018 |
van Haren J, Charafeddine R, Ettinger A, Wang H, Hahn KM, Wittmann T. Optical Control of EB1 Reveals Local Functions of the Microtubule +TIP Complex During Cell Migration and Division Biophysical Journal. 114: 382a. DOI: 10.1016/J.Bpj.2017.11.2115 |
0.398 |
|
| 2017 |
Webb BA, Dosey AM, Wittmann T, Kollman JM, Barber DL. The glycolytic enzyme phosphofructokinase-1 assembles into filaments. The Journal of Cell Biology. PMID 28646105 DOI: 10.1016/J.Bpj.2017.11.1268 |
0.365 |
|
| 2017 |
Pemble H, Kumar P, van Haren J, Wittmann T. GSK3-mediated CLASP2 phosphorylation modulates kinetochore dynamics. Journal of Cell Science. PMID 28232523 DOI: 10.1242/Jcs.194662 |
0.784 |
|
| 2016 |
Kenific CM, Wittmann T, Debnath J. Autophagy in adhesion and migration. Journal of Cell Science. PMID 27672021 DOI: 10.1242/Jcs.188490 |
0.389 |
|
| 2016 |
Ettinger A, van Haren J, Ribeiro SA, Wittmann T. Doublecortin Is Excluded from Growing Microtubule Ends and Recognizes the GDP-Microtubule Lattice. Current Biology : Cb. PMID 27238282 DOI: 10.1016/J.Cub.2016.04.020 |
0.52 |
|
| 2016 |
Kenific CM, Stehbens SJ, Goldsmith J, Leidal AM, Faure N, Ye J, Wittmann T, Debnath J. NBR1 enables autophagy-dependent focal adhesion turnover. The Journal of Cell Biology. 212: 577-590. PMID 26903539 DOI: 10.1083/Jcb.201503075 |
0.433 |
|
| 2016 |
Matov A, Rooij Jd, Gatlin J, Rohrberg J, Ahmad N, Aggarwal R, Simko J, Goga A, Ryan C, Wittmann T. Abstract 243: Investigating microtubule growth dynamics in patient-derived metastatic prostate cancer cells Cancer Research. 76: 243-243. DOI: 10.1158/1538-7445.Am2016-243 |
0.307 |
|
| 2015 |
Prochazka J, Prochazkova M, Du W, Spoutil F, Tureckova J, Hoch R, Shimogori T, Sedlacek R, Rubenstein JL, Wittmann T, Klein OD. Migration of Founder Epithelial Cells Drives Proper Molar Tooth Positioning and Morphogenesis. Developmental Cell. 35: 713-24. PMID 26702830 DOI: 10.1016/J.Devcel.2015.11.025 |
0.372 |
|
| 2014 |
Basu S, Sladecek S, Pemble H, Wittmann T, Slotman JA, van Cappellen W, Brenner HR, Galjart N. Acetylcholine receptor (AChR) clustering is regulated both by glycogen synthase kinase 3β (GSK3β)-dependent phosphorylation and the level of CLIP-associated protein 2 (CLASP2) mediating the capture of microtubule plus-ends. The Journal of Biological Chemistry. 289: 30857-67. PMID 25231989 DOI: 10.1074/Jbc.M114.589457 |
0.745 |
|
| 2014 |
Stehbens SJ, Wittmann T. Analysis of focal adhesion turnover: a quantitative live-cell imaging example. Methods in Cell Biology. 123: 335-46. PMID 24974036 DOI: 10.1016/B978-0-12-420138-5.00018-5 |
0.407 |
|
| 2014 |
Ettinger A, Wittmann T. Fluorescence live cell imaging. Methods in Cell Biology. 123: 77-94. PMID 24974023 DOI: 10.1016/B978-0-12-420138-5.00005-7 |
0.38 |
|
| 2014 |
Liz MA, Mar FM, Santos TE, Pimentel HI, Marques AM, Morgado MM, Vieira S, Sousa VF, Pemble H, Wittmann T, Sutherland C, Woodgett JR, Sousa MM. Neuronal deletion of GSK3β increases microtubule speed in the growth cone and enhances axon regeneration via CRMP-2 and independently of MAP1B and CLASP2. Bmc Biology. 12: 47. PMID 24923837 DOI: 10.1186/1741-7007-12-47 |
0.742 |
|
| 2014 |
Stehbens SJ, Paszek M, Pemble H, Ettinger A, Gierke S, Wittmann T. CLASPs link focal-adhesion-associated microtubule capture to localized exocytosis and adhesion site turnover. Nature Cell Biology. 16: 561-73. PMID 24859005 DOI: 10.1038/Ncb2975 |
0.732 |
|
| 2014 |
Tran CS, Eran Y, Ruch TR, Bryant DM, Datta A, Brakeman P, Kierbel A, Wittmann T, Metzger RJ, Mostov KE, Engel JN. Host cell polarity proteins participate in innate immunity to Pseudomonas aeruginosa infection. Cell Host & Microbe. 15: 636-43. PMID 24832456 DOI: 10.1016/J.Chom.2014.04.007 |
0.325 |
|
| 2014 |
Moon HM, Youn YH, Pemble H, Yingling J, Wittmann T, Wynshaw-Boris A. LIS1 controls mitosis and mitotic spindle organization via the LIS1-NDEL1-dynein complex. Human Molecular Genetics. 23: 449-66. PMID 24030547 DOI: 10.1093/Hmg/Ddt436 |
0.778 |
|
| 2014 |
van Haren J, Wittmann T. Light-Modulated Cell Adhesion to Control Cell and Tissue Morphogenesis Biophysical Journal. 106: 789a. DOI: 10.1016/J.Bpj.2013.11.4325 |
0.413 |
|
| 2013 |
Zhao X, Kumar P, Shah-Simpson S, Caradonna KL, Galjart N, Teygong C, Blader I, Wittmann T, Burleigh BA. Host microtubule plus-end binding protein CLASP1 influences sequential steps in the Trypanosoma cruzi infection process. Cellular Microbiology. 15: 571-84. PMID 23107073 DOI: 10.1111/Cmi.12056 |
0.45 |
|
| 2012 |
Lyle KS, Corleto JA, Wittmann T. Microtubule dynamics regulation contributes to endothelial morphogenesis. Bioarchitecture. 2: 220-7. PMID 23267416 DOI: 10.4161/bioa.22335 |
0.4 |
|
| 2012 |
Stehbens S, Wittmann T. Targeting and transport: how microtubules control focal adhesion dynamics. The Journal of Cell Biology. 198: 481-9. PMID 22908306 DOI: 10.1083/Jcb.201206050 |
0.551 |
|
| 2012 |
Kumar P, Wittmann T. +TIPs: SxIPping along microtubule ends. Trends in Cell Biology. 22: 418-28. PMID 22748381 DOI: 10.1016/J.Tcb.2012.05.005 |
0.482 |
|
| 2012 |
Gierke S, Wittmann T. EB1-recruited microtubule +TIP complexes coordinate protrusion dynamics during 3D epithelial remodeling. Current Biology : Cb. 22: 753-62. PMID 22483942 DOI: 10.1016/J.Cub.2012.02.069 |
0.772 |
|
| 2012 |
Kumar P, Chimenti MS, Pemble H, Schönichen A, Thompson O, Jacobson MP, Wittmann T. Multisite phosphorylation disrupts arginine-glutamate salt bridge networks required for binding of cytoplasmic linker-associated protein 2 (CLASP2) to end-binding protein 1 (EB1). The Journal of Biological Chemistry. 287: 17050-64. PMID 22467876 DOI: 10.1074/Jbc.M111.316661 |
0.763 |
|
| 2012 |
Stehbens S, Pemble H, Murrow L, Wittmann T. Imaging intracellular protein dynamics by spinning disk confocal microscopy. Methods in Enzymology. 504: 293-313. PMID 22264541 DOI: 10.1016/B978-0-12-391857-4.00015-X |
0.739 |
|
| 2011 |
Haynes J, Srivastava J, Madson N, Wittmann T, Barber DL. Dynamic actin remodeling during epithelial-mesenchymal transition depends on increased moesin expression. Molecular Biology of the Cell. 22: 4750-64. PMID 22031288 DOI: 10.1091/Mbc.E11-02-0119 |
0.457 |
|
| 2011 |
Elwell CA, Jiang S, Kim JH, Lee A, Wittmann T, Hanada K, Melancon P, Engel JN. Chlamydia trachomatis co-opts GBF1 and CERT to acquire host sphingomyelin for distinct roles during intracellular development. Plos Pathogens. 7: e1002198. PMID 21909260 DOI: 10.1371/Journal.Ppat.1002198 |
0.309 |
|
| 2010 |
Matov A, Applegate K, Kumar P, Thoma C, Krek W, Danuser G, Wittmann T. Analysis of microtubule dynamic instability using a plus-end growth marker. Nature Methods. 7: 761-8. PMID 20729842 DOI: 10.1038/Nmeth.1493 |
0.475 |
|
| 2010 |
Gierke S, Kumar P, Wittmann T. Analysis of microtubule polymerization dynamics in live cells. Methods in Cell Biology. 97: 15-33. PMID 20719263 DOI: 10.1016/S0091-679X(10)97002-7 |
0.776 |
|
| 2009 |
Kumar P, Lyle KS, Gierke S, Matov A, Danuser G, Wittmann T. GSK3beta phosphorylation modulates CLASP-microtubule association and lamella microtubule attachment. The Journal of Cell Biology. 184: 895-908. PMID 19289791 DOI: 10.1083/Jcb.200901042 |
0.79 |
|
| 2009 |
Lyle K, Kumar P, Wittmann T. SnapShot: Microtubule Regulators I. Cell. 136: 380, 380.e1. PMID 19167337 DOI: 10.1016/J.Cell.2009.01.010 |
0.549 |
|
| 2008 |
Wittmann T. EBs clip CLIPs to growing microtubule ends. The Journal of Cell Biology. 183: 1183-5. PMID 19103811 DOI: 10.1083/Jcb.200811136 |
0.443 |
|
| 2007 |
Delorme V, Machacek M, DerMardirossian C, Anderson KL, Wittmann T, Hanein D, Waterman-Storer C, Danuser G, Bokoch GM. Cofilin activity downstream of Pak1 regulates cell protrusion efficiency by organizing lamellipodium and lamella actin networks. Developmental Cell. 13: 646-62. PMID 17981134 DOI: 10.1016/J.Devcel.2007.08.011 |
0.408 |
|
| 2006 |
Kita K, Wittmann T, Näthke IS, Waterman-Storer CM. Adenomatous polyposis coli on microtubule plus ends in cell extensions can promote microtubule net growth with or without EB1. Molecular Biology of the Cell. 17: 2331-45. PMID 16525027 DOI: 10.1091/Mbc.E05-06-0498 |
0.511 |
|
| 2005 |
Wittmann T, Waterman-Storer CM. Spatial regulation of CLASP affinity for microtubules by Rac1 and GSK3beta in migrating epithelial cells. The Journal of Cell Biology. 169: 929-39. PMID 15955847 DOI: 10.1083/Jcb.200412114 |
0.548 |
|
| 2005 |
Wittmann T, Desai A. Microtubule cytoskeleton: a new twist at the end. Current Biology : Cb. 15: R126-9. PMID 15723782 DOI: 10.1016/J.Cub.2005.02.010 |
0.468 |
|
| 2005 |
Wittmann T, Waterman-Storer CM. Correction: Spatial regulation of CLASP affinity for microtubules by Rac1 and GSK3β in migrating epithelial cells Journal of Cell Biology. 171: 393-393. DOI: 10.1083/jcb.200412114101105c |
0.35 |
|
| 2004 |
Shirasu-Hiza M, Perlman ZE, Wittmann T, Karsenti E, Mitchison TJ. Eg5 causes elongation of meiotic spindles when flux-associated microtubule depolymerization is blocked. Current Biology : Cb. 14: 1941-5. PMID 15530396 DOI: 10.1016/J.Cub.2004.10.029 |
0.478 |
|
| 2004 |
Brunet S, Sardon T, Zimmerman T, Wittmann T, Pepperkok R, Karsenti E, Vernos I. Characterization of the TPX2 domains involved in microtubule nucleation and spindle assembly in Xenopus egg extracts. Molecular Biology of the Cell. 15: 5318-28. PMID 15385625 DOI: 10.1091/Mbc.E04-05-0385 |
0.433 |
|
| 2004 |
Wittmann T, Bokoch GM, Waterman-Storer CM. Regulation of microtubule destabilizing activity of Op18/stathmin downstream of Rac1. The Journal of Biological Chemistry. 279: 6196-203. PMID 14645234 DOI: 10.1074/Jbc.M307261200 |
0.481 |
|
| 2003 |
Wittmann T, Bokoch GM, Waterman-Storer CM. Regulation of leading edge microtubule and actin dynamics downstream of Rac1. The Journal of Cell Biology. 161: 845-51. PMID 12796474 DOI: 10.1083/Jcb.200303082 |
0.496 |
|
| 2003 |
Adams MC, Salmon WC, Gupton SL, Cohan CS, Wittmann T, Prigozhina N, Waterman-Storer CM. A high-speed multispectral spinning-disk confocal microscope system for fluorescent speckle microscopy of living cells. Methods (San Diego, Calif.). 29: 29-41. PMID 12543069 DOI: 10.1016/S1046-2023(02)00282-7 |
0.35 |
|
| 2002 |
Andersen SS, Wittmann T. Toward reconstitution of in vivo microtubule dynamics in vitro. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 24: 305-7. PMID 11948616 DOI: 10.1002/Bies.10084 |
0.478 |
|
| 2001 |
Wittmann T, Waterman-Storer CM. Cell motility: Can Rho GTPases and microtubules point the way? Journal of Cell Science. 114: 3795-3803. PMID 11719546 |
0.398 |
|
| 2001 |
Wittmann T, Hyman A, Desai A. The spindle: A dynamic assembly of microtubules and motors Nature Cell Biology. 3. PMID 11146647 DOI: 10.1038/35050669 |
0.466 |
|
| 2000 |
Wittmann T, Wilm M, Karsenti E, Vernos I. TPX2, A novel xenopus MAP involved in spindle pole organization. The Journal of Cell Biology. 149: 1405-18. PMID 10871281 DOI: 10.1083/Jcb.149.7.1405 |
0.492 |
|
| 2000 |
Ahmad FJ, Hughey J, Wittmann T, Hyman A, Greaser M, Baas PW. Motor proteins regulate force interactions between microtubules and microfilaments in the axon. Nature Cell Biology. 2: 276-80. PMID 10806478 DOI: 10.1038/35010544 |
0.366 |
|
| 1999 |
Wittmann T, Hyman T. Recombinant p50/dynamitin as a tool to examine the role of dynactin in intracellular processes Methods in Cell Biology. 61: 137-143. PMID 9891312 DOI: 10.1016/S0091-679X(08)61978-0 |
0.4 |
|
| 1998 |
Wittmann T, Boleti H, Antony C, Karsenti E, Vernos I. Localization of the kinesin-like protein Xklp2 to spindle poles requires a leucine zipper, a microtubule-associated protein, and dynein. The Journal of Cell Biology. 143: 673-85. PMID 9813089 DOI: 10.1083/Jcb.143.3.673 |
0.482 |
|
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