Matthew J. Paszek, Ph.D. - Publications

Affiliations: 
2009 University of Pennsylvania, Philadelphia, PA, United States 
Area:
cell adhesion and motility

43 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Park S, Paek JH, Colville MJ, Huang LT, Struzyk AP, Womack SJ, Neelamegham S, Reesink HL, Paszek MJ. Leucine zipper-based SAIM imaging identifies therapeutic agents to disrupt the cancer cell glycocalyx for enhanced immunotherapy. Biorxiv : the Preprint Server For Biology. PMID 39677754 DOI: 10.1101/2024.12.05.627089  0.304
2024 Beyrent E, Wei DT, Beacham GM, Park S, Zheng J, Paszek MJ, Hollopeter G. Dimerization activates the Inversin complex in . Biorxiv : the Preprint Server For Biology. PMID 38798613 DOI: 10.1101/2024.05.17.594761  0.497
2024 Park S, Colville MJ, Paek JH, Shurer CR, Singh A, Secor EJ, Sailer CJ, Huang LT, Kuo JC, Goudge MC, Su J, Kim M, DeLisa MP, Neelamegham S, Lammerding J, ... ... Paszek MJ, et al. Immunoengineering can overcome the glycocalyx armour of cancer cells. Nature Materials. PMID 38361041 DOI: 10.1038/s41563-024-01808-0  0.781
2024 Park S, Choi S, Shimpi AA, Estroff LA, Fischbach C, Paszek MJ. COLLAGEN MINERALIZATION DECREASES NK CELL-MEDIATED CYTOTOXICITY OF BREAST CANCER CELLS VIA INCREASED GLYCOCALYX THICKNESS. Biorxiv : the Preprint Server For Biology. PMID 38328161 DOI: 10.1101/2024.01.20.576377  0.6
2024 Park S, Choi S, Shimpi AA, Estroff LA, Fischbach C, Paszek MJ. Collagen Mineralization Decreases Nk Cell-Mediated Cytotoxicity of Breast Cancer Cells via Increased Glycocalyx Thickness. Advanced Materials (Deerfield Beach, Fla.). e2311505. PMID 38279892 DOI: 10.1002/adma.202311505  0.6
2023 Tharp K, Park S, Timblin G, Richards A, Twells N, Riley N, Peltan E, Shon J, Stevenson E, Tsui K, Palomba F, Lefebvre A, Soens R, Ayad N, Hoeve-Scott JT, ... ... Paszek M, et al. The microenvironment dictates glycocalyx construction and immune surveillance. Research Square. PMID 37645943 DOI: 10.21203/rs.3.rs-3164966/v1  0.726
2023 Wallace M, Fedorchak GR, Agrawal R, Gilbert RM, Patel J, Park S, Paszek M, Lammerding J. The lamin A/C Ig-fold undergoes cell density-dependent changes that alter epitope binding. Nucleus (Austin, Tex.). 14: 2180206. PMID 36809122 DOI: 10.1080/19491034.2023.2180206  0.519
2022 Shimpi AA, Tan ML, Vilkhovoy M, Dai D, Roberts LM, Kuo J, Huang L, Varner JD, Paszek M, Fischbach C. Convergent Approaches to Delineate the Metabolic Regulation of Tumor Invasion by Hyaluronic Acid Biosynthesis. Advanced Healthcare Materials. e2202224. PMID 36479976 DOI: 10.1002/adhm.202202224  0.754
2022 Park S, Chin-Hun Kuo J, Reesink HL, Paszek MJ. Recombinant mucin biotechnology and engineering. Advanced Drug Delivery Reviews. 114618. PMID 36375719 DOI: 10.1016/j.addr.2022.114618  0.532
2022 Colville M, Park S, Singh A, Paszek M, Zipfel WR. Azimuthal Beam Scanning Microscope Design and Implementation for Axial Localization with Scanning Angle Interference Microscopy. Methods in Molecular Biology (Clifton, N.J.). 2393: 127-152. PMID 34837177 DOI: 10.1007/978-1-0716-1803-5_7  0.46
2020 Kuo J, Goudge MC, Metzloff AE, Huang LT, Colville MJ, Park S, Zipfel WR, Paszek MJ. Litmus-Body: a Molecularly Targeted Sensor for Cell-Surface pH Measurements. Acs Sensors. PMID 32337979 DOI: 10.1021/Acssensors.9B02080  0.542
2020 Cheng Z, Shurer CR, Schmidt S, Gupta VK, Chuang G, Su J, Watkins AR, Shetty A, Spector JA, Hui CY, Reesink HL, Paszek MJ. The surface stress of biomedical silicones is a stimulant of cellular response. Science Advances. 6: eaay0076. PMID 32300645 DOI: 10.1126/Sciadv.Aay0076  0.753
2020 Noble JM, Monét Roberts L, Vidavsky N, Chiou AE, Fischbach C, Paszek MJ, Estroff LA, Kourkoutis LF. Direct Comparison of Optical and Electron Microscopy Methods for Structural Characterization of Extracellular Vesicles. Journal of Structural Biology. 107474. PMID 32032755 DOI: 10.1016/J.Jsb.2020.107474  0.369
2020 Lu C, Jones T, Pedram K, Bertozzi C, Paszek M, Cui B. Large Glycocalyx Proteins are Excluded from the Interface between Cell Membrane and Vertical Nanostructures Biophysical Journal. 118: 396a. DOI: 10.1016/J.Bpj.2019.11.2251  0.338
2019 Colville MJ, Park S, Zipfel WR, Paszek MJ. High-speed device synchronization in optical microscopy with an open-source hardware control platform. Scientific Reports. 9: 12188. PMID 31434941 DOI: 10.1038/S41598-019-48455-Z  0.513
2019 Shurer CR, Kuo JC, Roberts LM, Gandhi JG, Colville MJ, Enoki TA, Pan H, Su J, Noble JM, Hollander MJ, O'Donnell JP, Yin R, Pedram K, Möckl L, Kourkoutis LF, ... ... Paszek MJ, et al. Physical Principles of Membrane Shape Regulation by the Glycocalyx. Cell. PMID 31056282 DOI: 10.1016/J.Cell.2019.04.017  0.71
2019 Cox EC, Thornlow DN, Jones MA, Fuller JL, Merritt JH, Paszek MJ, Alabi CA, DeLisa MP. Antibody-mediated endocytosis of polysialic acid enables intracellular delivery and cytotoxicity of a glycan-directed antibody-drug conjugate. Cancer Research. PMID 30808675 DOI: 10.1158/0008-5472.Can-18-3119  0.396
2019 Gandhi JG, Koch DL, Paszek MJ. Equilibrium Modeling of the Mechanics and Structure of the Cancer Glycocalyx. Biophysical Journal. PMID 30736980 DOI: 10.1016/J.Bpj.2018.12.023  0.437
2019 Shurer CR, Wang Y, Feeney E, Head SE, Zhang VX, Su J, Cheng Z, Stark MA, Bonassar LJ, Reesink HL, Paszek MJ. Stable recombinant production of codon-scrambled lubricin and mucin in human cells. Biotechnology and Bioengineering. PMID 30684357 DOI: 10.1002/Bit.26940  0.758
2019 Shurer CR, Head SE, Goudge MC, Paszek MJ. Mucin-Coating Technologies for Protection and Reduced Aggregation of Cellular Production Systems. Biotechnology and Bioengineering. PMID 30636317 DOI: 10.1002/Bit.26916  0.78
2019 Pan H, Paszek M. Combinational Genetically Encoded Toolbox for Cell-Surface Mucin Biopolymer Engineering Biophysical Journal. 116: 273a. DOI: 10.1016/J.Bpj.2018.11.1476  0.335
2018 Chin-Hun Kuo J, Gandhi JG, Zia RN, Paszek MJ. Physical biology of the cancer cell glycocalyx. Nature Physics. 14: 658-669. PMID 33859716 DOI: 10.1038/s41567-018-0186-9  0.315
2018 Shurer CR, Colville MJ, Gupta VK, Head SE, Kai F, Lakins JN, Paszek MJ. Genetically Encoded Toolbox for Glycocalyx Engineering: Tunable Control of Cell Adhesion, Survival, and Cancer Cell Behaviors. Acs Biomaterials Science & Engineering. 4: 388-399. PMID 29805991 DOI: 10.1021/Acsbiomaterials.7B00037  0.796
2018 Kuo JC, Gandhi JG, Zia RN, Paszek MJ. Physical biology of the cancer cell glycocalyx Nature Physics. 14: 658-669. DOI: 10.1038/S41567-018-0186-9  0.44
2018 Noble JM, Vidavsky N, Roberts LM, Chiou A, Paszek MJ, Fischbach C, Estroff LA, Kourkoutis LF. Revealing Mechanisms of Microvesicle Biogenesis in Breast Cancer Cells via in situ Microscopy Microscopy and Microanalysis. 24: 1256-1257. DOI: 10.1017/S1431927618006761  0.372
2018 Pan H, Paszek M. Glycoprotein Crowding Affects Cell Membrane Signalling Biophysical Journal. 114: 202a. DOI: 10.1016/J.Bpj.2017.11.1127  0.338
2017 Reesink HL, Sutton RM, Shurer CR, Peterson RP, Tan JS, Su J, Paszek MJ, Nixon AJ. Galectin-1 and galectin-3 expression in equine mesenchymal stromal cells (MSCs), synovial fibroblasts and chondrocytes, and the effect of inflammation on MSC motility. Stem Cell Research & Therapy. 8: 243. PMID 29096716 DOI: 10.1186/S13287-017-0691-2  0.767
2017 Shurer C, Paszek M. Abstract A59: Glycosylation dynamically tunes the biophysical properties of the cancer cell glycocalyx Cancer Research. 77. DOI: 10.1158/1538-7445.Epso16-A59  0.48
2017 Gandhi JG, Paszek MJ, Koch DL. Mechanics of Glycoprotein Organization in the Glycocalyx Biophysical Journal. 112: 292a. DOI: 10.1016/J.Bpj.2016.11.1582  0.413
2014 Rubashkin MG, Cassereau L, Bainer R, DuFort CC, Yui Y, Ou G, Paszek MJ, Davidson MW, Chen YY, Weaver VM. Force engages vinculin and promotes tumor progression by enhancing PI3K activation of phosphatidylinositol (3,4,5)-triphosphate. Cancer Research. 74: 4597-611. PMID 25183785 DOI: 10.1158/0008-5472.Can-13-3698  0.608
2014 Paszek MJ, DuFort CC, Rossier O, Bainer R, Mouw JK, Godula K, Hudak JE, Lakins JN, Wijekoon AC, Cassereau L, Rubashkin MG, Magbanua MJ, Thorn KS, Davidson MW, Rugo HS, et al. The cancer glycocalyx mechanically primes integrin-mediated growth and survival. Nature. 511: 319-25. PMID 25030168 DOI: 10.1038/Nature13535  0.691
2014 Stehbens SJ, Paszek M, Pemble H, Ettinger A, Gierke S, Wittmann T. CLASPs link focal-adhesion-associated microtubule capture to localized exocytosis and adhesion site turnover. Nature Cell Biology. 16: 561-73. PMID 24859005 DOI: 10.1038/Ncb2975  0.379
2014 Burnette DT, Shao L, Ott C, Pasapera AM, Fischer RS, Baird MA, Der Loughian C, Delanoe-Ayari H, Paszek MJ, Davidson MW, Betzig E, Lippincott-Schwartz J. A contractile and counterbalancing adhesion system controls the 3D shape of crawling cells. The Journal of Cell Biology. 205: 83-96. PMID 24711500 DOI: 10.1083/Jcb.201311104  0.378
2014 Rubashkin MG, Dufort C, Oakes P, Paszek M, Ou G, Lakins J, Davidson M, Gardel M, Weaver V. The Nanoscale Organization of Focal Adhesion Signaling Complexes can Reflect Changes in Cellular Contractility and Motility Biophysical Journal. 106: 575a-576a. DOI: 10.1016/J.Bpj.2013.11.3190  0.606
2013 Agus DB, Alexander JF, Arap W, Ashili S, Aslan JE, Austin RH, Backman V, Bethel KJ, Bonneau R, Chen WC, Chen-Tanyolac C, Choi NC, Curley SA, Dallas M, ... ... Paszek MJ, et al. A physical sciences network characterization of non-tumorigenic and metastatic cells. Scientific Reports. 3: 1449. PMID 23618955 DOI: 10.1038/Srep01449  0.732
2012 Paszek MJ, DuFort CC, Rubashkin MG, Davidson MW, Thorn KS, Liphardt JT, Weaver VM. Scanning angle interference microscopy reveals cell dynamics at the nanoscale. Nature Methods. 9: 825-7. PMID 22751201 DOI: 10.1038/Nmeth.2077  0.582
2012 Miroshnikova Y, Acerbi I, Ilkhanizadeh S, Paszek M, Persson A, Weaver V. 159 The Role of the Biophysical Properties of the Glycocalyx and Extracellular Matrix Tension in Enhancing Glioma Cell Invasion European Journal of Cancer. 48: S38-S39. DOI: 10.1016/S0959-8049(12)70859-6  0.541
2011 DuFort CC, Paszek MJ, Weaver VM. Balancing forces: architectural control of mechanotransduction. Nature Reviews. Molecular Cell Biology. 12: 308-19. PMID 21508987 DOI: 10.1038/Nrm3112  0.585
2011 Miroshnikova YA, Acerbi I, Persson A, Paszek MJ, Weiss WA, Weaver VM. Abstract LB-96: Extrinsic and intrinsic force and GBM aggression Cancer Research. 71. DOI: 10.1158/1538-7445.Am2011-Lb-96  0.59
2010 Paszek M, Weaver V. Enforcing order on signaling Science. 327: 1335-1336. PMID 20223974 DOI: 10.1126/Science.1187865  0.565
2009 Paszek MJ, Boettiger D, Weaver VM, Hammer DA. Integrin clustering is driven by mechanical resistance from the glycocalyx and the substrate. Plos Computational Biology. 5: e1000604. PMID 20011123 DOI: 10.1371/Journal.Pcbi.1000604  0.647
2005 Paszek MJ, Zahir N, Johnson KR, Lakins JN, Rozenberg GI, Gefen A, Reinhart-King CA, Margulies SS, Dembo M, Boettiger D, Hammer DA, Weaver VM. Tensional homeostasis and the malignant phenotype. Cancer Cell. 8: 241-54. PMID 16169468 DOI: 10.1016/J.Ccr.2005.08.010  0.747
2004 Paszek MJ, Weaver VM. The tension mounts: mechanics meets morphogenesis and malignancy. Journal of Mammary Gland Biology and Neoplasia. 9: 325-42. PMID 15838603 DOI: 10.1007/S10911-004-1404-X  0.58
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