Year |
Citation |
Score |
2024 |
Pena ES, Batty CJ, Hendy DA, Yang S, Ontiveros-Padilla L, Stiepel RT, Ting JP, Ainslie KM, Bachelder EM. Comparative study of acetalated-dextran microparticle fabrication methods for a clinically translatable subunit-based influenza vaccine. International Journal of Pharmaceutics. 652: 123836. PMID 38266940 DOI: 10.1016/j.ijpharm.2024.123836 |
0.321 |
|
2022 |
Batty CJ, Amouzougan EA, A Carlock M, Ross TM, Bachelder EM, Ainslie KM. Sustained delivery of CpG oligodeoxynucleotide by acetalated dextran microparticles augments effector response to Computationally Optimized Broadly Reactive Antigen (COBRA) influenza hemagglutinin. International Journal of Pharmaceutics. 630: 122429. PMID 36436743 DOI: 10.1016/j.ijpharm.2022.122429 |
0.311 |
|
2020 |
Moore K, Batty CJ, Stiepel R, Genito C, Bachelder EM, Ainslie KM. Injectable, ribbon-like microconfetti biopolymer platform for vaccine applications. Acs Applied Materials & Interfaces. PMID 32805875 DOI: 10.1021/Acsami.0C10276 |
0.415 |
|
2020 |
Graham-Gurysh EG, Murthy AB, Moore KM, Hingtgen SD, Bachelder EM, Ainslie KM. Synergistic drug combinations for a precision medicine approach to interstitial glioblastoma therapy. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 32335153 DOI: 10.1016/J.Jconrel.2020.04.028 |
0.352 |
|
2020 |
Moore KM, Graham-Gurysh EG, Bomba HN, Murthy AB, Bachelder EM, Hingtgen SD, Ainslie KM. Impact of composite scaffold degradation rate on neural stem cell persistence in the glioblastoma surgical resection cavity. Materials Science & Engineering. C, Materials For Biological Applications. 111: 110846. PMID 32279815 DOI: 10.1016/J.Msec.2020.110846 |
0.334 |
|
2020 |
Varma DM, Zahid MSH, Bachelder EM, Ainslie KM. Formulation of host-targeted therapeutics against bacterial infections. Translational Research : the Journal of Laboratory and Clinical Medicine. PMID 32268128 DOI: 10.1016/J.Trsl.2020.03.009 |
0.333 |
|
2020 |
Graham-Gurysh EG, Moore KM, Schorzman AN, Lee T, Zamboni WC, Hingtgen SD, Bachelder EM, Ainslie KM. Tumor Responsive and Tunable Polymeric Platform for Optimized Delivery of Paclitaxel to Treat Glioblastoma. Acs Applied Materials & Interfaces. PMID 32252517 DOI: 10.1021/Acsami.0C04102 |
0.387 |
|
2019 |
Steipel RT, Gallovic MD, Batty CJ, Bachelder EM, Ainslie KM. Electrospray for generation of drug delivery and vaccine particles applied in vitro and in vivo. Materials Science & Engineering. C, Materials For Biological Applications. 105: 110070. PMID 31546372 DOI: 10.1016/J.Msec.2019.110070 |
0.381 |
|
2019 |
Zahid MSH, Johnson MM, Tokarski RJ, Satoskar AR, Fuchs JR, Bachelder EM, Ainslie KM. Evaluation of synergy between host and pathogen-directed therapies against intracellular Leishmania donovani. International Journal For Parasitology. Drugs and Drug Resistance. 10: 125-132. PMID 31493763 DOI: 10.1016/J.Ijpddr.2019.08.004 |
0.339 |
|
2019 |
Watkins-Schulz R, Tiet P, Gallovic MD, Junkins RD, Batty C, Bachelder EM, Ainslie KM, Ting JPY. A microparticle platform for STING-targeted immunotherapy enhances natural killer cell- and CD8 T cell-mediated anti-tumor immunity. Biomaterials. 205: 94-105. PMID 30909112 DOI: 10.1016/J.Biomaterials.2019.03.011 |
0.378 |
|
2018 |
Cheng N, Watkins-Schulz R, Junkins RD, David CN, Johnson BM, Montgomery SA, Peine KJ, Darr DB, Yuan H, McKinnon KP, Liu Q, Miao L, Huang L, Bachelder EM, Ainslie KM, et al. A nanoparticle-incorporated STING activator enhances antitumor immunity in PD-L1-insensitive models of triple-negative breast cancer. Jci Insight. 3. PMID 30429378 DOI: 10.1172/Jci.Insight.120638 |
0.333 |
|
2018 |
Krovi SA, Gallovic MD, Keller AM, Bhat M, Tiet P, Chen N, Collier MA, Gurysh EG, Pino EN, Johnson MM, Shamim Hasan Zahid M, Cottrell ML, Pirone JR, Kashuba AD, Kwiek JJ, ... Bachelder EM, et al. Injectable Long-acting Human Immunodeficiency Virus Antiretroviral Prodrugs with Improved Pharmacokinetic Profiles. International Journal of Pharmaceutics. PMID 30308272 DOI: 10.1016/J.Ijpharm.2018.10.017 |
0.344 |
|
2018 |
Johnson MM, Collier MA, Hoang KV, Pino EN, Graham-Gurysh EG, Gallovic MD, Zahid MSH, Chen N, Schlesinger L, Gunn JS, Bachelder EM, Ainslie KM. In vivo and Cellular Trafficking of Acetalated Dextran Microparticles for Delivery of a Host-Directed Therapy for Salmonella enterica Serovar Typhi Infection. Molecular Pharmaceutics. PMID 30296381 DOI: 10.1021/Acs.Molpharmaceut.8B00802 |
0.409 |
|
2018 |
Collier MA, Junkins RD, Gallovic MD, Johnson BM, Johnson MM, Macintyre AN, Sempowski GD, Bachelder EM, Ting JP, Ainslie KM. Acetalated Dextran microparticles for co-delivery of STING and TLR7/8 agonists. Molecular Pharmaceutics. PMID 30281314 DOI: 10.1021/Acs.Molpharmaceut.8B00579 |
0.409 |
|
2018 |
Chen N, Gallovic MD, Tiet P, Ting JP, Ainslie KM, Bachelder EM. Investigation of tunable acetalated dextran microparticle platform to optimize M2e-based influenza vaccine efficacy. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 30261204 DOI: 10.1016/J.Jconrel.2018.09.020 |
0.357 |
|
2018 |
Batty CJ, Tiet P, Bachelder EM, Ainslie KM. Drug Delivery for Cancer Immunotherapy and Vaccines. Pharmaceutical Nanotechnology. PMID 30227827 DOI: 10.2174/2211738506666180918122337 |
0.302 |
|
2018 |
Chen N, Kroger CJ, Tisch RM, Bachelder EM, Ainslie KM. Prevention of Type 1 Diabetes with Acetalated Dextran Microparticles Containing Rapamycin and Pancreatic Peptide P31. Advanced Healthcare Materials. e1800341. PMID 30051618 DOI: 10.1002/Adhm.201800341 |
0.355 |
|
2018 |
Chen N, Johnson MM, Collier MA, Gallovic MD, Bachelder EM, Ainslie KM. Tunable degradation of acetalated dextran microparticles enables controlled vaccine adjuvant and antigen delivery to modulate adaptive immune responses. Journal of Controlled Release : Official Journal of the Controlled Release Society. 273: 147-159. PMID 29407676 DOI: 10.1016/J.Jconrel.2018.01.027 |
0.428 |
|
2018 |
Graham-Gurysh EG, Moore KM, Satterlee AB, Sheets KT, Lin FC, Bachelder EM, Miller CR, Hingtgen S, Ainslie KM. Sustained Delivery of Doxorubicin via Acetalated Dextran Scaffold Prevents Glioblastoma Recurrence after Surgical Resection. Molecular Pharmaceutics. PMID 29342360 DOI: 10.1021/Acs.Molpharmaceut.7B01114 |
0.383 |
|
2018 |
Cheng N, Watkins-Schulz R, Junkins R, David C, Johnson BM, Montgomery SA, Peine KJ, Darr DB, Yuan H, McKinnon KP, Liu Q, Miao L, Huang L, Bachelder EM, Ainslie KM, et al. Abstract LB-126: Nanoparticle-incorporated STING activator as an immunotherapeutic for PD-L1 resistant triple-negative breast cancer Cancer Research. 78. DOI: 10.1158/1538-7445.Am2018-Lb-126 |
0.316 |
|
2017 |
Junkins RD, Gallovic MD, Johnson BM, Collier MA, Watkins-Schulz R, Cheng N, David CN, McGee CE, Sempowski GD, Shterev I, McKinnon K, Bachelder EM, Ainslie KM, Ting JP. A robust microparticle platform for a STING-targeted adjuvant that enhances both humoral and cellular immunity during vaccination. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 29170142 DOI: 10.1016/J.Jconrel.2017.11.030 |
0.452 |
|
2017 |
Webb LM, Amici SA, Jablonski KA, Savardekar H, Panfil AR, Li L, Zhou W, Peine K, Karkhanis V, Bachelder EM, Ainslie KM, Green PL, Li C, Baiocchi RA, Guerau-de-Arellano M. PRMT5-Selective Inhibitors Suppress Inflammatory T Cell Responses and Experimental Autoimmune Encephalomyelitis. Journal of Immunology (Baltimore, Md. : 1950). PMID 28087667 DOI: 10.4049/Jimmunol.1601702 |
0.321 |
|
2016 |
Gallovic MD, Bandyopadhyay S, Borteh H, Montjoy DG, Collier MA, Peine KJ, Wyslouzil BE, Bachelder EM, Ainslie KM. Microparticles formulated from a family of novel silylated polysaccharides demonstrate inherent immunostimulatory properties and tunable hydrolytic degradability. Journal of Materials Chemistry. B. 4: 4302-4312. PMID 32263412 DOI: 10.1039/C6Tb00745G |
0.435 |
|
2016 |
Bachelder EM, Pino EN, Ainslie KM. Acetalated Dextran: A Tunable and Acid-Labile Biopolymer with Facile Synthesis and a Range of Applications. Chemical Reviews. PMID 28032507 DOI: 10.1021/Acs.Chemrev.6B00532 |
0.409 |
|
2016 |
Collier MA, Bachelder EM, Ainslie KM. Electrosprayed Myocet-like Liposomes: An Alternative to Traditional Liposome Production. Pharmaceutical Research. PMID 27896588 DOI: 10.1007/S11095-016-2072-4 |
0.366 |
|
2016 |
Gallovic MD, Schully KL, Bell MG, Elberson MA, Palmer JR, Darko CA, Bachelder EM, Wyslouzil BE, Keane-Myers AM, Ainslie KM. Acetalated Dextran Microparticulate Vaccine Formulated via Coaxial Electrospray Preserves Toxin Neutralization and Enhances Murine Survival Following Inhalational Bacillus Anthracis Exposure. Advanced Healthcare Materials. PMID 27594343 DOI: 10.1002/Adhm.201600642 |
0.352 |
|
2016 |
Chen N, Collier MA, Gallovic MD, Collins GC, Sanchez CC, Fernandes EQ, Bachelder EM, Ainslie KM. Degradation of acetalated dextran can be broadly tuned based on cyclic acetal coverage and molecular weight. International Journal of Pharmaceutics. PMID 27543351 DOI: 10.1016/J.Ijpharm.2016.08.031 |
0.414 |
|
2016 |
Collier MA, Gallovic MD, Bachelder EM, Sykes CD, Kashuba A, Ainslie KM. Saquinavir Loaded Acetalated Dextran Microconfetti - a Long Acting Protease Inhibitor Injectable. Pharmaceutical Research. PMID 27154460 DOI: 10.1007/S11095-016-1936-Y |
0.339 |
|
2016 |
Hoang KV, Curry H, Collier MA, Borteh H, Bachelder EM, Schlesinger LS, Gunn JS, Ainslie KM. Needle-Free Delivery of Acetalated Dextran-Encapsulated AR-12 Protects Mice from Francisella tularensis Lethal Challenge. Antimicrobial Agents and Chemotherapy. 60: 2052-62. PMID 26787696 DOI: 10.1128/Aac.02228-15 |
0.312 |
|
2016 |
Collier MA, Peine KJ, Gautam S, Oghumu S, Varikuti S, Borteh H, Papenfuss TL, Sataoskar AR, Bachelder EM, Ainslie KM. Host-mediated Leishmania donovani treatment using AR-12 encapsulated in acetalated dextran microparticles. International Journal of Pharmaceutics. 499: 186-194. PMID 26768723 DOI: 10.1016/J.Ijpharm.2016.01.004 |
0.342 |
|
2016 |
Gallovic MD, Montjoy DG, Collier MA, Do C, Wyslouzil BE, Bachelder EM, Ainslie KM. Chemically modified inulin microparticles serving dual function as a protein antigen delivery vehicle and immunostimulatory adjuvant. Biomaterials Science. PMID 26753184 DOI: 10.1039/C5Bm00451A |
0.414 |
|
2016 |
Gallovic MD, Bandyopadhyay S, Borteh H, Montjoy DG, Collier MA, Peine KJ, Wyslouzil BE, Bachelder EM, Ainslie KM. Microparticles formulated from a family of novel silylated polysaccharides demonstrate inherent immunostimulatory properties and tunable hydrolytic degradability Journal of Materials Chemistry B. 4: 4302-4312. DOI: 10.1039/c6tb00745g |
0.341 |
|
2015 |
Gupta G, Peine KJ, Abdelhamid D, Snider H, Shelton AB, Rao L, Kotha SR, Huntsman AC, Varikuti S, Oghumu S, Naman CB, Pan L, Parinandi NL, Papenfuss TL, Kinghorn AD, ... Bachelder EM, et al. A Novel Sterol Isolated from a Plant Used by Mayan Traditional Healers Is Effective in Treatment of Visceral Leishmaniasis Caused by Leishmania donovani. Acs Infectious Diseases. 1: 497-506. PMID 27623316 DOI: 10.1021/Acsinfecdis.5B00081 |
0.351 |
|
2015 |
Duong AD, Collier MA, Bachelder EM, Wyslouzil BE, Ainslie KM. One Step Encapsulation of Small Molecule Drugs in Liposomes via Electrospray-Remote Loading. Molecular Pharmaceutics. PMID 26568143 DOI: 10.1021/Acs.Molpharmaceut.5B00528 |
0.373 |
|
2015 |
Schully KL, Bell MG, Prouty AM, Gallovic MD, Gautam S, Peine KJ, Sharma S, Bachelder EM, Pesce JT, Elberson MA, Ainslie KM, Keane-Myers A. Evaluation of a biodegradable microparticulate polymer as a carrier for Burkholderia pseudomallei subunit vaccines in a mouse model of melioidosis. International Journal of Pharmaceutics. 495: 849-61. PMID 26428631 DOI: 10.1016/J.Ijpharm.2015.09.059 |
0.413 |
|
2014 |
Hoang KV, Borteh HM, Rajaram MV, Peine KJ, Curry H, Collier MA, Homsy ML, Bachelder EM, Gunn JS, Schlesinger LS, Ainslie KM. Acetalated dextran encapsulated AR-12 as a host-directed therapy to control Salmonella infection. International Journal of Pharmaceutics. 477: 334-43. PMID 25447826 DOI: 10.1016/J.Ijpharm.2014.10.022 |
0.376 |
|
2014 |
Peine KJ, Guerau-de-Arellano M, Lee P, Kanthamneni N, Severin M, Probst GD, Peng H, Yang Y, Vangundy Z, Papenfuss TL, Lovett-Racke AE, Bachelder EM, Ainslie KM. Treatment of experimental autoimmune encephalomyelitis by codelivery of disease associated Peptide and dexamethasone in acetalated dextran microparticles. Molecular Pharmaceutics. 11: 828-35. PMID 24433027 DOI: 10.1021/Mp4005172 |
0.334 |
|
2013 |
Collier MA, Gallovic MD, Peine KJ, Duong AD, Bachelder EM, Gunn JS, Schlesinger LS, Ainslie KM. Delivery of host cell-directed therapeutics for intracellular pathogen clearance. Expert Review of Anti-Infective Therapy. 11: 1225-35. PMID 24134600 DOI: 10.1586/14787210.2013.845524 |
0.357 |
|
2013 |
Peine KJ, Bachelder EM, Vangundy Z, Papenfuss T, Brackman DJ, Gallovic MD, Schully K, Pesce J, Keane-Myers A, Ainslie KM. Efficient delivery of the toll-like receptor agonists polyinosinic:polycytidylic acid and CpG to macrophages by acetalated dextran microparticles. Molecular Pharmaceutics. 10: 2849-57. PMID 23768126 DOI: 10.1021/Mp300643D |
0.444 |
|
2013 |
Borteh HM, Gallovic MD, Sharma S, Peine KJ, Miao S, Brackman DJ, Gregg K, Xu Y, Guo X, Guan J, Bachelder EM, Ainslie KM. Electrospun acetalated dextran scaffolds for temporal release of therapeutics. Langmuir : the Acs Journal of Surfaces and Colloids. 29: 7957-65. PMID 23725054 DOI: 10.1021/La400541E |
0.384 |
|
2013 |
Schully KL, Sharma S, Peine KJ, Pesce J, Elberson MA, Fonseca ME, Prouty AM, Bell MG, Borteh H, Gallovic M, Bachelder EM, Keane-Myers A, Ainslie KM. Rapid vaccination using an acetalated dextran microparticulate subunit vaccine confers protection against triplicate challenge by bacillus anthracis. Pharmaceutical Research. 30: 1349-61. PMID 23354770 DOI: 10.1007/S11095-013-0975-X |
0.328 |
|
2013 |
Duong AD, Sharma S, Peine KJ, Gupta G, Satoskar AR, Bachelder EM, Wyslouzil BE, Ainslie KM. Electrospray encapsulation of toll-like receptor agonist resiquimod in polymer microparticles for the treatment of visceral leishmaniasis. Molecular Pharmaceutics. 10: 1045-55. PMID 23320733 DOI: 10.1021/Mp3005098 |
0.415 |
|
2012 |
Kauffman KJ, Do C, Sharma S, Gallovic MD, Bachelder EM, Ainslie KM. Synthesis and characterization of acetalated dextran polymer and microparticles with ethanol as a degradation product. Acs Applied Materials & Interfaces. 4: 4149-55. PMID 22833690 DOI: 10.1021/Am3008888 |
0.407 |
|
2012 |
Kanthamneni N, Sharma S, Meenach SA, Billet B, Zhao JC, Bachelder EM, Ainslie KM. Enhanced stability of horseradish peroxidase encapsulated in acetalated dextran microparticles stored outside cold chain conditions. International Journal of Pharmaceutics. 431: 101-10. PMID 22548844 DOI: 10.1016/J.Ijpharm.2012.04.043 |
0.36 |
|
2012 |
Meenach SA, Kim YJ, Kauffman KJ, Kanthamneni N, Bachelder EM, Ainslie KM. Synthesis, optimization, and characterization of camptothecin-loaded acetalated dextran porous microparticles for pulmonary delivery. Molecular Pharmaceutics. 9: 290-8. PMID 22149217 DOI: 10.1021/Mp2003785 |
0.387 |
|
2012 |
Kauffman KJ, Kanthamneni N, Meenach SA, Pierson BC, Bachelder EM, Ainslie KM. Optimization of rapamycin-loaded acetalated dextran microparticles for immunosuppression. International Journal of Pharmaceutics. 422: 356-63. PMID 22037446 DOI: 10.1016/J.Ijpharm.2011.10.034 |
0.418 |
|
2010 |
Cohen JA, Beaudette TT, Cohen JL, Broaders KE, Bachelder EM, Fréchet JMJ. Acetal-modified dextran microparticles with controlled degradation kinetics and surface functionality for gene delivery in phagocytic and non-phagocytic cells Advanced Materials. 22: 3593-3597. PMID 20518040 DOI: 10.1002/Adma.201000307 |
0.434 |
|
2010 |
Bachelder EM, Beaudette TT, Broaders KE, Fréchet JMJ, Albrecht MT, Mateczun AJ, Ainslie KM, Pesce JT, Keane-Myers AM. In vitro analysis of acetalated dextran microparticles as a potent delivery platform for vaccine adjuvants Molecular Pharmaceutics. 7: 826-835. PMID 20230025 DOI: 10.1021/Mp900311X |
0.403 |
|
2009 |
Ainslie KM, Lowe RD, Beaudette TT, Petty L, Bachelder EM, Desai TA. Microfabricated devices for enhanced bioadhesive drug delivery: attachment to and small-molecule release through a cell monolayer under flow. Small (Weinheim An Der Bergstrasse, Germany). 5: 2857-63. PMID 19787677 DOI: 10.1002/Smll.200901254 |
0.327 |
|
2009 |
Beaudette TT, Cohen JA, Bachelder EM, Broaders KE, Cohen JL, Engleman EG, Fréchet JMJ. Chemoselective ligation in the functionalization of polysaccharide-based particles Journal of the American Chemical Society. 131: 10360-10361. PMID 19591467 DOI: 10.1021/Ja903984S |
0.357 |
|
2009 |
Beaudette TT, Bachelder EM, Cohen JA, Obermeyer AC, Broaders KE, Fréchet JM, Kang ES, Mende I, Tseng WW, Davidson MG, Engleman EG. In vivo studies on the effect of co-encapsulation of CpG DNA and antigen in acid-degradable microparticle vaccines. Molecular Pharmaceutics. 6: 1160-9. PMID 19415922 DOI: 10.1021/Mp900038E |
0.411 |
|
2009 |
Cohen JA, Beaudette TT, Tseng WW, Bachelder EM, Mende I, Engleman EG, Fréchet JM. T-cell activation by antigen-loaded pH-sensitive hydrogel particles in vivo: the effect of particle size. Bioconjugate Chemistry. 20: 111-9. PMID 19102625 DOI: 10.1021/Bc800338N |
0.382 |
|
2008 |
Bachelder EM, Beaudette TT, Broaders KE, Paramonov SE, Dashe J, Fréchet JM. Acid-degradable polyurethane particles for protein-based vaccines: biological evaluation and in vitro analysis of particle degradation products. Molecular Pharmaceutics. 5: 876-84. PMID 18710254 DOI: 10.1021/Mp800068X |
0.38 |
|
2008 |
Bachelder EM, Beaudette TT, Broaders KE, Dashe J, Fréchet JM. Acetal-derivatized dextran: an acid-responsive biodegradable material for therapeutic applications. Journal of the American Chemical Society. 130: 10494-5. PMID 18630909 DOI: 10.1021/Ja803947S |
0.393 |
|
2008 |
Paramonov SE, Bachelder EM, Beaudette TT, Standley SM, Lee CC, Dashe J, Fréchet JM. Fully acid-degradable biocompatible polyacetal microparticles for drug delivery. Bioconjugate Chemistry. 19: 911-9. PMID 18373356 DOI: 10.1021/Bc7004472 |
0.35 |
|
2007 |
Ainslie KM, Bachelder EM, Borkar S, Zahr AS, Sen A, Badding JV, Pishko MV. Cell adhesion on nanofibrous polytetrafluoroethylene (nPTFE). Langmuir : the Acs Journal of Surfaces and Colloids. 23: 747-54. PMID 17209629 DOI: 10.1021/La060948S |
0.332 |
|
2007 |
Ainslie KM, Bachelder EM, Sharma G, Grimes CA, Pishko MV. Macrophage cell adhesion and inflammation cytokines on magnetostrictive nanowires Nanotoxicology. 1: 279-290. DOI: 10.1080/17435390701781142 |
0.3 |
|
2004 |
Alpan O, Bachelder E, Isil E, Arnheiter H, Matzinger P. 'Educated' dendritic cells act as messengers from memory to naive T helper cells. Nature Immunology. 5: 615-622. PMID 15156140 DOI: 10.1038/Ni1077 |
0.309 |
|
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