Eric M. Bachelder, Ph.D. - Publications

Affiliations: 
2006 The University of Nebraska - Lincoln, Lincoln, NE 
Area:
Chemical Engineering, Rehabilitation and Therapy

59/107 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Ehrenzeller SA, Lukesh NR, Stiepel RT, Middleton DD, Nuzzolo SM, Tate AJ, Batty CJ, Bachelder EM, Ainslie KM. Comparison of emulsion and spray methods for fabrication of rapamycin-loaded acetalated dextran microparticles. Rsc Pharmaceutics. 1: 727-741. PMID 39415944 DOI: 10.1039/d4pm00054d  0.306
2024 Pena ES, Batty CJ, Hendy DA, Yang S, Ontiveros-Padilla L, Stiepel RT, Ting JP, Ainslie KM, Bachelder EM. Comparative study of acetalated-dextran microparticle fabrication methods for a clinically translatable subunit-based influenza vaccine. International Journal of Pharmaceutics. 652: 123836. PMID 38266940 DOI: 10.1016/j.ijpharm.2024.123836  0.322
2022 Batty CJ, Amouzougan EA, A Carlock M, Ross TM, Bachelder EM, Ainslie KM. Sustained delivery of CpG oligodeoxynucleotide by acetalated dextran microparticles augments effector response to Computationally Optimized Broadly Reactive Antigen (COBRA) influenza hemagglutinin. International Journal of Pharmaceutics. 630: 122429. PMID 36436743 DOI: 10.1016/j.ijpharm.2022.122429  0.312
2020 Moore K, Batty CJ, Stiepel R, Genito C, Bachelder EM, Ainslie KM. Injectable, ribbon-like microconfetti biopolymer platform for vaccine applications. Acs Applied Materials & Interfaces. PMID 32805875 DOI: 10.1021/Acsami.0C10276  0.416
2020 Graham-Gurysh EG, Murthy AB, Moore KM, Hingtgen SD, Bachelder EM, Ainslie KM. Synergistic drug combinations for a precision medicine approach to interstitial glioblastoma therapy. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 32335153 DOI: 10.1016/J.Jconrel.2020.04.028  0.352
2020 Moore KM, Graham-Gurysh EG, Bomba HN, Murthy AB, Bachelder EM, Hingtgen SD, Ainslie KM. Impact of composite scaffold degradation rate on neural stem cell persistence in the glioblastoma surgical resection cavity. Materials Science & Engineering. C, Materials For Biological Applications. 111: 110846. PMID 32279815 DOI: 10.1016/J.Msec.2020.110846  0.334
2020 Varma DM, Zahid MSH, Bachelder EM, Ainslie KM. Formulation of host-targeted therapeutics against bacterial infections. Translational Research : the Journal of Laboratory and Clinical Medicine. PMID 32268128 DOI: 10.1016/J.Trsl.2020.03.009  0.333
2020 Graham-Gurysh EG, Moore KM, Schorzman AN, Lee T, Zamboni WC, Hingtgen SD, Bachelder EM, Ainslie KM. Tumor Responsive and Tunable Polymeric Platform for Optimized Delivery of Paclitaxel to Treat Glioblastoma. Acs Applied Materials & Interfaces. PMID 32252517 DOI: 10.1021/Acsami.0C04102  0.388
2019 Steipel RT, Gallovic MD, Batty CJ, Bachelder EM, Ainslie KM. Electrospray for generation of drug delivery and vaccine particles applied in vitro and in vivo. Materials Science & Engineering. C, Materials For Biological Applications. 105: 110070. PMID 31546372 DOI: 10.1016/J.Msec.2019.110070  0.382
2019 Zahid MSH, Johnson MM, Tokarski RJ, Satoskar AR, Fuchs JR, Bachelder EM, Ainslie KM. Evaluation of synergy between host and pathogen-directed therapies against intracellular Leishmania donovani. International Journal For Parasitology. Drugs and Drug Resistance. 10: 125-132. PMID 31493763 DOI: 10.1016/J.Ijpddr.2019.08.004  0.339
2019 Watkins-Schulz R, Tiet P, Gallovic MD, Junkins RD, Batty C, Bachelder EM, Ainslie KM, Ting JPY. A microparticle platform for STING-targeted immunotherapy enhances natural killer cell- and CD8 T cell-mediated anti-tumor immunity. Biomaterials. 205: 94-105. PMID 30909112 DOI: 10.1016/J.Biomaterials.2019.03.011  0.378
2018 Cheng N, Watkins-Schulz R, Junkins RD, David CN, Johnson BM, Montgomery SA, Peine KJ, Darr DB, Yuan H, McKinnon KP, Liu Q, Miao L, Huang L, Bachelder EM, Ainslie KM, et al. A nanoparticle-incorporated STING activator enhances antitumor immunity in PD-L1-insensitive models of triple-negative breast cancer. Jci Insight. 3. PMID 30429378 DOI: 10.1172/Jci.Insight.120638  0.333
2018 Krovi SA, Gallovic MD, Keller AM, Bhat M, Tiet P, Chen N, Collier MA, Gurysh EG, Pino EN, Johnson MM, Shamim Hasan Zahid M, Cottrell ML, Pirone JR, Kashuba AD, Kwiek JJ, ... Bachelder EM, et al. Injectable Long-acting Human Immunodeficiency Virus Antiretroviral Prodrugs with Improved Pharmacokinetic Profiles. International Journal of Pharmaceutics. PMID 30308272 DOI: 10.1016/J.Ijpharm.2018.10.017  0.344
2018 Johnson MM, Collier MA, Hoang KV, Pino EN, Graham-Gurysh EG, Gallovic MD, Zahid MSH, Chen N, Schlesinger L, Gunn JS, Bachelder EM, Ainslie KM. In vivo and Cellular Trafficking of Acetalated Dextran Microparticles for Delivery of a Host-Directed Therapy for Salmonella enterica Serovar Typhi Infection. Molecular Pharmaceutics. PMID 30296381 DOI: 10.1021/Acs.Molpharmaceut.8B00802  0.409
2018 Collier MA, Junkins RD, Gallovic MD, Johnson BM, Johnson MM, Macintyre AN, Sempowski GD, Bachelder EM, Ting JP, Ainslie KM. Acetalated Dextran microparticles for co-delivery of STING and TLR7/8 agonists. Molecular Pharmaceutics. PMID 30281314 DOI: 10.1021/Acs.Molpharmaceut.8B00579  0.41
2018 Chen N, Gallovic MD, Tiet P, Ting JP, Ainslie KM, Bachelder EM. Investigation of tunable acetalated dextran microparticle platform to optimize M2e-based influenza vaccine efficacy. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 30261204 DOI: 10.1016/J.Jconrel.2018.09.020  0.358
2018 Batty CJ, Tiet P, Bachelder EM, Ainslie KM. Drug Delivery for Cancer Immunotherapy and Vaccines. Pharmaceutical Nanotechnology. PMID 30227827 DOI: 10.2174/2211738506666180918122337  0.303
2018 Chen N, Kroger CJ, Tisch RM, Bachelder EM, Ainslie KM. Prevention of Type 1 Diabetes with Acetalated Dextran Microparticles Containing Rapamycin and Pancreatic Peptide P31. Advanced Healthcare Materials. e1800341. PMID 30051618 DOI: 10.1002/Adhm.201800341  0.355
2018 Chen N, Johnson MM, Collier MA, Gallovic MD, Bachelder EM, Ainslie KM. Tunable degradation of acetalated dextran microparticles enables controlled vaccine adjuvant and antigen delivery to modulate adaptive immune responses. Journal of Controlled Release : Official Journal of the Controlled Release Society. 273: 147-159. PMID 29407676 DOI: 10.1016/J.Jconrel.2018.01.027  0.429
2018 Graham-Gurysh EG, Moore KM, Satterlee AB, Sheets KT, Lin FC, Bachelder EM, Miller CR, Hingtgen S, Ainslie KM. Sustained Delivery of Doxorubicin via Acetalated Dextran Scaffold Prevents Glioblastoma Recurrence after Surgical Resection. Molecular Pharmaceutics. PMID 29342360 DOI: 10.1021/Acs.Molpharmaceut.7B01114  0.383
2018 Cheng N, Watkins-Schulz R, Junkins R, David C, Johnson BM, Montgomery SA, Peine KJ, Darr DB, Yuan H, McKinnon KP, Liu Q, Miao L, Huang L, Bachelder EM, Ainslie KM, et al. Abstract LB-126: Nanoparticle-incorporated STING activator as an immunotherapeutic for PD-L1 resistant triple-negative breast cancer Cancer Research. 78. DOI: 10.1158/1538-7445.Am2018-Lb-126  0.316
2017 Junkins RD, Gallovic MD, Johnson BM, Collier MA, Watkins-Schulz R, Cheng N, David CN, McGee CE, Sempowski GD, Shterev I, McKinnon K, Bachelder EM, Ainslie KM, Ting JP. A robust microparticle platform for a STING-targeted adjuvant that enhances both humoral and cellular immunity during vaccination. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 29170142 DOI: 10.1016/J.Jconrel.2017.11.030  0.453
2017 Webb LM, Amici SA, Jablonski KA, Savardekar H, Panfil AR, Li L, Zhou W, Peine K, Karkhanis V, Bachelder EM, Ainslie KM, Green PL, Li C, Baiocchi RA, Guerau-de-Arellano M. PRMT5-Selective Inhibitors Suppress Inflammatory T Cell Responses and Experimental Autoimmune Encephalomyelitis. Journal of Immunology (Baltimore, Md. : 1950). PMID 28087667 DOI: 10.4049/Jimmunol.1601702  0.321
2016 Gallovic MD, Bandyopadhyay S, Borteh H, Montjoy DG, Collier MA, Peine KJ, Wyslouzil BE, Bachelder EM, Ainslie KM. Microparticles formulated from a family of novel silylated polysaccharides demonstrate inherent immunostimulatory properties and tunable hydrolytic degradability. Journal of Materials Chemistry. B. 4: 4302-4312. PMID 32263412 DOI: 10.1039/C6Tb00745G  0.436
2016 Bachelder EM, Pino EN, Ainslie KM. Acetalated Dextran: A Tunable and Acid-Labile Biopolymer with Facile Synthesis and a Range of Applications. Chemical Reviews. PMID 28032507 DOI: 10.1021/Acs.Chemrev.6B00532  0.41
2016 Collier MA, Bachelder EM, Ainslie KM. Electrosprayed Myocet-like Liposomes: An Alternative to Traditional Liposome Production. Pharmaceutical Research. PMID 27896588 DOI: 10.1007/S11095-016-2072-4  0.366
2016 Gallovic MD, Schully KL, Bell MG, Elberson MA, Palmer JR, Darko CA, Bachelder EM, Wyslouzil BE, Keane-Myers AM, Ainslie KM. Acetalated Dextran Microparticulate Vaccine Formulated via Coaxial Electrospray Preserves Toxin Neutralization and Enhances Murine Survival Following Inhalational Bacillus Anthracis Exposure. Advanced Healthcare Materials. PMID 27594343 DOI: 10.1002/Adhm.201600642  0.353
2016 Chen N, Collier MA, Gallovic MD, Collins GC, Sanchez CC, Fernandes EQ, Bachelder EM, Ainslie KM. Degradation of acetalated dextran can be broadly tuned based on cyclic acetal coverage and molecular weight. International Journal of Pharmaceutics. PMID 27543351 DOI: 10.1016/J.Ijpharm.2016.08.031  0.414
2016 Collier MA, Gallovic MD, Bachelder EM, Sykes CD, Kashuba A, Ainslie KM. Saquinavir Loaded Acetalated Dextran Microconfetti - a Long Acting Protease Inhibitor Injectable. Pharmaceutical Research. PMID 27154460 DOI: 10.1007/S11095-016-1936-Y  0.34
2016 Hoang KV, Curry H, Collier MA, Borteh H, Bachelder EM, Schlesinger LS, Gunn JS, Ainslie KM. Needle-Free Delivery of Acetalated Dextran-Encapsulated AR-12 Protects Mice from Francisella tularensis Lethal Challenge. Antimicrobial Agents and Chemotherapy. 60: 2052-62. PMID 26787696 DOI: 10.1128/Aac.02228-15  0.312
2016 Collier MA, Peine KJ, Gautam S, Oghumu S, Varikuti S, Borteh H, Papenfuss TL, Sataoskar AR, Bachelder EM, Ainslie KM. Host-mediated Leishmania donovani treatment using AR-12 encapsulated in acetalated dextran microparticles. International Journal of Pharmaceutics. 499: 186-194. PMID 26768723 DOI: 10.1016/J.Ijpharm.2016.01.004  0.342
2016 Gallovic MD, Montjoy DG, Collier MA, Do C, Wyslouzil BE, Bachelder EM, Ainslie KM. Chemically modified inulin microparticles serving dual function as a protein antigen delivery vehicle and immunostimulatory adjuvant. Biomaterials Science. PMID 26753184 DOI: 10.1039/C5Bm00451A  0.414
2016 Gallovic MD, Bandyopadhyay S, Borteh H, Montjoy DG, Collier MA, Peine KJ, Wyslouzil BE, Bachelder EM, Ainslie KM. Microparticles formulated from a family of novel silylated polysaccharides demonstrate inherent immunostimulatory properties and tunable hydrolytic degradability Journal of Materials Chemistry B. 4: 4302-4312. DOI: 10.1039/c6tb00745g  0.341
2015 Gupta G, Peine KJ, Abdelhamid D, Snider H, Shelton AB, Rao L, Kotha SR, Huntsman AC, Varikuti S, Oghumu S, Naman CB, Pan L, Parinandi NL, Papenfuss TL, Kinghorn AD, ... Bachelder EM, et al. A Novel Sterol Isolated from a Plant Used by Mayan Traditional Healers Is Effective in Treatment of Visceral Leishmaniasis Caused by Leishmania donovani. Acs Infectious Diseases. 1: 497-506. PMID 27623316 DOI: 10.1021/Acsinfecdis.5B00081  0.351
2015 Duong AD, Collier MA, Bachelder EM, Wyslouzil BE, Ainslie KM. One Step Encapsulation of Small Molecule Drugs in Liposomes via Electrospray-Remote Loading. Molecular Pharmaceutics. PMID 26568143 DOI: 10.1021/Acs.Molpharmaceut.5B00528  0.373
2015 Schully KL, Bell MG, Prouty AM, Gallovic MD, Gautam S, Peine KJ, Sharma S, Bachelder EM, Pesce JT, Elberson MA, Ainslie KM, Keane-Myers A. Evaluation of a biodegradable microparticulate polymer as a carrier for Burkholderia pseudomallei subunit vaccines in a mouse model of melioidosis. International Journal of Pharmaceutics. 495: 849-61. PMID 26428631 DOI: 10.1016/J.Ijpharm.2015.09.059  0.414
2014 Hoang KV, Borteh HM, Rajaram MV, Peine KJ, Curry H, Collier MA, Homsy ML, Bachelder EM, Gunn JS, Schlesinger LS, Ainslie KM. Acetalated dextran encapsulated AR-12 as a host-directed therapy to control Salmonella infection. International Journal of Pharmaceutics. 477: 334-43. PMID 25447826 DOI: 10.1016/J.Ijpharm.2014.10.022  0.376
2014 Peine KJ, Guerau-de-Arellano M, Lee P, Kanthamneni N, Severin M, Probst GD, Peng H, Yang Y, Vangundy Z, Papenfuss TL, Lovett-Racke AE, Bachelder EM, Ainslie KM. Treatment of experimental autoimmune encephalomyelitis by codelivery of disease associated Peptide and dexamethasone in acetalated dextran microparticles. Molecular Pharmaceutics. 11: 828-35. PMID 24433027 DOI: 10.1021/Mp4005172  0.334
2013 Collier MA, Gallovic MD, Peine KJ, Duong AD, Bachelder EM, Gunn JS, Schlesinger LS, Ainslie KM. Delivery of host cell-directed therapeutics for intracellular pathogen clearance. Expert Review of Anti-Infective Therapy. 11: 1225-35. PMID 24134600 DOI: 10.1586/14787210.2013.845524  0.357
2013 Peine KJ, Bachelder EM, Vangundy Z, Papenfuss T, Brackman DJ, Gallovic MD, Schully K, Pesce J, Keane-Myers A, Ainslie KM. Efficient delivery of the toll-like receptor agonists polyinosinic:polycytidylic acid and CpG to macrophages by acetalated dextran microparticles. Molecular Pharmaceutics. 10: 2849-57. PMID 23768126 DOI: 10.1021/Mp300643D  0.444
2013 Borteh HM, Gallovic MD, Sharma S, Peine KJ, Miao S, Brackman DJ, Gregg K, Xu Y, Guo X, Guan J, Bachelder EM, Ainslie KM. Electrospun acetalated dextran scaffolds for temporal release of therapeutics. Langmuir : the Acs Journal of Surfaces and Colloids. 29: 7957-65. PMID 23725054 DOI: 10.1021/La400541E  0.384
2013 Schully KL, Sharma S, Peine KJ, Pesce J, Elberson MA, Fonseca ME, Prouty AM, Bell MG, Borteh H, Gallovic M, Bachelder EM, Keane-Myers A, Ainslie KM. Rapid vaccination using an acetalated dextran microparticulate subunit vaccine confers protection against triplicate challenge by bacillus anthracis. Pharmaceutical Research. 30: 1349-61. PMID 23354770 DOI: 10.1007/S11095-013-0975-X  0.329
2013 Duong AD, Sharma S, Peine KJ, Gupta G, Satoskar AR, Bachelder EM, Wyslouzil BE, Ainslie KM. Electrospray encapsulation of toll-like receptor agonist resiquimod in polymer microparticles for the treatment of visceral leishmaniasis. Molecular Pharmaceutics. 10: 1045-55. PMID 23320733 DOI: 10.1021/Mp3005098  0.415
2012 Kauffman KJ, Do C, Sharma S, Gallovic MD, Bachelder EM, Ainslie KM. Synthesis and characterization of acetalated dextran polymer and microparticles with ethanol as a degradation product. Acs Applied Materials & Interfaces. 4: 4149-55. PMID 22833690 DOI: 10.1021/Am3008888  0.408
2012 Kanthamneni N, Sharma S, Meenach SA, Billet B, Zhao JC, Bachelder EM, Ainslie KM. Enhanced stability of horseradish peroxidase encapsulated in acetalated dextran microparticles stored outside cold chain conditions. International Journal of Pharmaceutics. 431: 101-10. PMID 22548844 DOI: 10.1016/J.Ijpharm.2012.04.043  0.361
2012 Meenach SA, Kim YJ, Kauffman KJ, Kanthamneni N, Bachelder EM, Ainslie KM. Synthesis, optimization, and characterization of camptothecin-loaded acetalated dextran porous microparticles for pulmonary delivery. Molecular Pharmaceutics. 9: 290-8. PMID 22149217 DOI: 10.1021/Mp2003785  0.387
2012 Kauffman KJ, Kanthamneni N, Meenach SA, Pierson BC, Bachelder EM, Ainslie KM. Optimization of rapamycin-loaded acetalated dextran microparticles for immunosuppression. International Journal of Pharmaceutics. 422: 356-63. PMID 22037446 DOI: 10.1016/J.Ijpharm.2011.10.034  0.419
2010 Cohen JA, Beaudette TT, Cohen JL, Broaders KE, Bachelder EM, Fréchet JMJ. Acetal-modified dextran microparticles with controlled degradation kinetics and surface functionality for gene delivery in phagocytic and non-phagocytic cells Advanced Materials. 22: 3593-3597. PMID 20518040 DOI: 10.1002/Adma.201000307  0.434
2010 Bachelder EM, Beaudette TT, Broaders KE, Fréchet JMJ, Albrecht MT, Mateczun AJ, Ainslie KM, Pesce JT, Keane-Myers AM. In vitro analysis of acetalated dextran microparticles as a potent delivery platform for vaccine adjuvants Molecular Pharmaceutics. 7: 826-835. PMID 20230025 DOI: 10.1021/Mp900311X  0.403
2009 Ainslie KM, Lowe RD, Beaudette TT, Petty L, Bachelder EM, Desai TA. Microfabricated devices for enhanced bioadhesive drug delivery: attachment to and small-molecule release through a cell monolayer under flow. Small (Weinheim An Der Bergstrasse, Germany). 5: 2857-63. PMID 19787677 DOI: 10.1002/Smll.200901254  0.327
2009 Beaudette TT, Cohen JA, Bachelder EM, Broaders KE, Cohen JL, Engleman EG, Fréchet JMJ. Chemoselective ligation in the functionalization of polysaccharide-based particles Journal of the American Chemical Society. 131: 10360-10361. PMID 19591467 DOI: 10.1021/Ja903984S  0.357
2009 Beaudette TT, Bachelder EM, Cohen JA, Obermeyer AC, Broaders KE, Fréchet JM, Kang ES, Mende I, Tseng WW, Davidson MG, Engleman EG. In vivo studies on the effect of co-encapsulation of CpG DNA and antigen in acid-degradable microparticle vaccines. Molecular Pharmaceutics. 6: 1160-9. PMID 19415922 DOI: 10.1021/Mp900038E  0.412
2009 Cohen JA, Beaudette TT, Tseng WW, Bachelder EM, Mende I, Engleman EG, Fréchet JM. T-cell activation by antigen-loaded pH-sensitive hydrogel particles in vivo: the effect of particle size. Bioconjugate Chemistry. 20: 111-9. PMID 19102625 DOI: 10.1021/Bc800338N  0.383
2008 Bachelder EM, Beaudette TT, Broaders KE, Paramonov SE, Dashe J, Fréchet JM. Acid-degradable polyurethane particles for protein-based vaccines: biological evaluation and in vitro analysis of particle degradation products. Molecular Pharmaceutics. 5: 876-84. PMID 18710254 DOI: 10.1021/Mp800068X  0.38
2008 Bachelder EM, Beaudette TT, Broaders KE, Dashe J, Fréchet JM. Acetal-derivatized dextran: an acid-responsive biodegradable material for therapeutic applications. Journal of the American Chemical Society. 130: 10494-5. PMID 18630909 DOI: 10.1021/Ja803947S  0.394
2008 Paramonov SE, Bachelder EM, Beaudette TT, Standley SM, Lee CC, Dashe J, Fréchet JM. Fully acid-degradable biocompatible polyacetal microparticles for drug delivery. Bioconjugate Chemistry. 19: 911-9. PMID 18373356 DOI: 10.1021/Bc7004472  0.35
2007 Ainslie KM, Bachelder EM, Borkar S, Zahr AS, Sen A, Badding JV, Pishko MV. Cell adhesion on nanofibrous polytetrafluoroethylene (nPTFE). Langmuir : the Acs Journal of Surfaces and Colloids. 23: 747-54. PMID 17209629 DOI: 10.1021/La060948S  0.332
2007 Ainslie KM, Bachelder EM, Sharma G, Grimes CA, Pishko MV. Macrophage cell adhesion and inflammation cytokines on magnetostrictive nanowires Nanotoxicology. 1: 279-290. DOI: 10.1080/17435390701781142  0.3
2004 Alpan O, Bachelder E, Isil E, Arnheiter H, Matzinger P. 'Educated' dendritic cells act as messengers from memory to naive T helper cells. Nature Immunology. 5: 615-622. PMID 15156140 DOI: 10.1038/Ni1077  0.309
Low-probability matches (unlikely to be authored by this person)
2023 Hendy DA, Johnson-Weaver BT, Batty CJ, Bachelder EM, Abraham SN, Staats HF, Ainslie KM. Delivery of small molecule mast cell activators for West Nile Virus vaccination using acetalated dextran microparticles. International Journal of Pharmaceutics. 634: 122658. PMID 36731641 DOI: 10.1016/j.ijpharm.2023.122658  0.299
2022 Rose Lukesh N, Middleton DD, Bachelder EM, Ainslie KM. Particle-Based therapies for antigen specific treatment of type 1 diabetes. International Journal of Pharmaceutics. 631: 122500. PMID 36529362 DOI: 10.1016/j.ijpharm.2022.122500  0.294
2020 Moore KM, Murthy AB, Graham-Gurysh EG, Hingtgen SD, Bachelder EM, Ainslie KM. Polymeric Biomaterial Scaffolds for Tumoricidal Stem Cell Glioblastoma Therapy. Acs Biomaterials Science & Engineering. 6: 3762-3777. PMID 33463324 DOI: 10.1021/Acsbiomaterials.0C00477  0.291
2009 Broaders KE, Cohen JA, Beaudette TT, Bachelder EM, Fréchet JM. Acetalated dextran is a chemically and biologically tunable material for particulate immunotherapy. Proceedings of the National Academy of Sciences of the United States of America. 106: 5497-502. PMID 19321415 DOI: 10.1073/Pnas.0901592106  0.291
2022 Eckshtain-Levi M, Batty CJ, Lifshits LM, McCammitt B, Moore KM, Amouzougan EA, Stiepel RT, Duggan E, Ross TM, Bachelder EM, Ainslie KM. Metal-Organic Coordination Polymer for Delivery of a Subunit Broadly Acting Influenza Vaccine. Acs Applied Materials & Interfaces. 14: 28548-28558. PMID 35704854 DOI: 10.1021/acsami.2c04671  0.287
2023 Hendy DA, Haven A, Bachelder EM, Ainslie KM. Preclinical developments in the delivery of protein antigens for vaccination. Expert Opinion On Drug Delivery. 20: 367-384. PMID 36731824 DOI: 10.1080/17425247.2023.2176844  0.283
2014 Peine KJ, Gupta G, Brackman DJ, Papenfuss TL, Ainslie KM, Satoskar AR, Bachelder EM. Liposomal resiquimod for the treatment of Leishmania donovani infection. The Journal of Antimicrobial Chemotherapy. 69: 168-75. PMID 23956375 DOI: 10.1093/Jac/Dkt320  0.283
2007 Lee KS, Scanga CA, Bachelder EM, Chen Q, Snapper CM. TLR2 synergizes with both TLR4 and TLR9 for induction of the MyD88-dependent splenic cytokine and chemokine response to Streptococcus pneumoniae. Cellular Immunology. 245: 103-10. PMID 17521621 DOI: 10.1016/J.Cellimm.2007.04.003  0.276
2022 Batty CJ, Gallovic MD, Williams J, Ross TM, Bachelder EM, Ainslie KM. Multiplexed electrospray enables high throughput production of cGAMP microparticles to serve as an adjuvant for a broadly acting influenza vaccine. International Journal of Pharmaceutics. 622: 121839. PMID 35623484 DOI: 10.1016/j.ijpharm.2022.121839  0.273
2024 Roque JA, Lukesh NR, Hendy DA, Dixon TA, Islam MJ, Ontiveros-Padilla L, Pena ES, Lifshits LM, Simpson SR, Batty CJ, Bachelder EM, Ainslie KM. Enhancement of subunit vaccine delivery with zinc-carnosine coordination polymer through the addition of mannan. International Journal of Pharmaceutics. 124076. PMID 38569976 DOI: 10.1016/j.ijpharm.2024.124076  0.273
2023 Hendy DA, Lifshits LM, Batty CJ, Carlock MA, Ross TM, Mousa JJ, Bachelder EM, Ainslie KM. Zinc Carnosine Metal-Organic Coordination Polymer as a Potent Broadly Active Influenza Vaccine Platform with In Vitro Shelf-Stability. Molecular Pharmaceutics. PMID 37603310 DOI: 10.1021/acs.molpharmaceut.3c00424  0.272
2021 Pena ES, Graham-Gurysh EG, Bachelder EM, Ainslie KM. Design of Biopolymer-Based Interstitial Therapies for the Treatment of Glioblastoma. International Journal of Molecular Sciences. 22. PMID 34884965 DOI: 10.3390/ijms222313160  0.271
2024 Simpson SR, Middleton D, Lukesh NR, Islam MJ, Bachelder EM, Ainslie KM. Microparticles incorporating dual apoptotic factors to inhibit anti-inflammatory effects in macrophages. Journal of Pharmaceutical Sciences. PMID 38852674 DOI: 10.1016/j.xphs.2024.05.030  0.268
2023 Ontiveros-Padilla L, Batty CJ, Hendy DA, Pena ES, Roque JA, Stiepel RT, Carlock MA, Simpson SR, Ross TM, Abraham SN, Staats HF, Bachelder EM, Ainslie KM. Development of a broadly active influenza intranasal vaccine adjuvanted with self-assembled particles composed of mastoparan-7 and CpG. Frontiers in Immunology. 14: 1103765. PMID 37033992 DOI: 10.3389/fimmu.2023.1103765  0.258
2021 Genito CJ, Batty CJ, Bachelder EM, Ainslie KM. Considerations for Size, Surface Charge, Polymer Degradation, Co-Delivery, and Manufacturability in the Development of Polymeric Particle Vaccines for Infectious Diseases. Advanced Nanobiomed Research. 2000041. PMID 33681864 DOI: 10.1002/anbr.202000041  0.255
2023 Batty CJ, Pena ES, Amouzougan EA, Moore KM, Ainslie KM, Bachelder EM. Humoral Response to the Acetalated Dextran M2e Vaccine is Enhanced by Antigen Surface Conjugation. Bioconjugate Chemistry. 34: 1447-1458. PMID 37458383 DOI: 10.1021/acs.bioconjchem.3c00223  0.254
2020 Stiepel RT, Batty CJ, MacRaild CA, Norton RS, Bachelder E, Ainslie KM. Merozoite Surface Protein 2 Adsorbed onto Acetalated Dextran Microparticles for Malaria Vaccination. International Journal of Pharmaceutics. 120168. PMID 33309558 DOI: 10.1016/j.ijpharm.2020.120168  0.253
2005 Bachelder EM, Ainslie KM, Pishko MV. Utilizing a quartz crystal microbalance for quantifying CD4+ T cell counts Sensor Letters. 3: 211-215. DOI: 10.1166/Sl.2005.029  0.252
2022 Stiepel RT, Pena ES, Ehrenzeller SA, Gallovic MD, Lifshits LM, Genito CJ, Bachelder EM, Ainslie KM. A predictive mechanistic model of drug release from surface eroding polymeric nanoparticles. Journal of Controlled Release : Official Journal of the Controlled Release Society. 351: 883-895. PMID 36208792 DOI: 10.1016/j.jconrel.2022.09.067  0.251
2019 Manaster AJ, Batty C, Tiet P, Ooi A, Bachelder EM, Ainslie KM, Broaders KE. Oxidation-Sensitive Dextran-Based Polymer with Improved Processability through Stable Boronic Ester Groups. Acs Applied Bio Materials. 2: 3755-3762. PMID 35021349 DOI: 10.1021/acsabm.9b00399  0.245
2023 Batty CJ, Lifshits LM, Hendy DA, Eckshtain-Levi M, Ontiveros-Padilla LA, Carlock MA, Ross TM, Bachelder EM, Ainslie KM. Vinyl Sulfone-functionalized Acetalated Dextran Microparticles as a Subunit Broadly Acting Influenza Vaccine. The Aaps Journal. 25: 22. PMID 36720729 DOI: 10.1208/s12248-023-00786-6  0.245
2016 Gupta G, Peine KJ, Abdelhamid D, Snider H, Shelton AB, Rao L, Kotha SR, Huntsman AC, Varikuti S, Oghumu S, Naman CB, Pan L, Parinandi NL, Papenfuss TL, Kinghorn AD, ... Bachelder EM, et al. A Novel Sterol Isolated from a Plant Used by Mayan Traditional Healers Is Effective in Treatment of Visceral Leishmaniasis Caused by Leishmania donovani Acs Infectious Diseases. 1: 497-506. DOI: 10.1021/acsinfecdis.5b00081  0.239
2022 Varma DM, Batty CJ, Stiepel RT, Graham-Gurysh EG, Roque JA, Pena ES, Hasan Zahid MS, Qiu K, Anselmo A, Hill DB, Ross TM, Bachelder EM, Ainslie KM. Development of an Intranasal Gel for the Delivery of a Broadly Acting Subunit Influenza Vaccine. Acs Biomaterials Science & Engineering. PMID 35353486 DOI: 10.1021/acsbiomaterials.2c00015  0.235
2023 Woodring RN, Gurysh EG, Bachelder EM, Ainslie KM. Drug Delivery Systems for Localized Cancer Combination Therapy. Acs Applied Bio Materials. PMID 36791273 DOI: 10.1021/acsabm.2c00973  0.233
2024 Williamson GL, Middleton DD, Ainslie KM, Bachelder EM. Acetalated dextran: a novel delivery platform for particle-based vaccines. Expert Opinion On Drug Delivery. 22: 1-5. PMID 39709953 DOI: 10.1080/17425247.2024.2442671  0.232
2023 Pena ES, Lifshits LM, Eckshtain-Levi M, Bachelder EM, Ainslie KM. Metal-organic coordination polymers for delivery of immunomodulatory agents, and infectious disease and cancer vaccines. Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology. e1877. PMID 36630948 DOI: 10.1002/wnan.1877  0.228
2025 Stiepel RT, Simpson SR, Lukesh NR, Middleton DD, Hendy DA, Ontiveros-Padilla L, Ehrenzeller SA, Islam MJ, Pena ES, Carlock MA, Ross TM, Bachelder EM, Ainslie KM. Induction of Antigen-Specific Tolerance in a Multiple Sclerosis Model without Broad Immunosuppression. Acs Nano. PMID 39812522 DOI: 10.1021/acsnano.4c14698  0.222
2024 Zhang X, Shi H, Hendy DA, Bachelder EM, Ainslie KM, Ross TM. Multi-COBRA hemagglutinin formulated with cGAMP microparticles elicits protective immune responses against influenza viruses. Msphere. e0016024. PMID 38920382 DOI: 10.1128/msphere.00160-24  0.219
2022 Hendy DA, Amouzougan EA, Young IC, Bachelder EM, Ainslie KM. Nano/microparticle Formulations for Universal Influenza Vaccines. The Aaps Journal. 24: 24. PMID 34997352 DOI: 10.1208/s12248-021-00676-9  0.218
2023 Mei KC, Stiepel RT, Bonacquisti E, Jasiewicz NE, Chaudhari AP, Tiwade PB, Bachelder EM, Ainslie KM, Fenton OS, Nguyen J. Single-tailed heterocyclic carboxamide lipids for macrophage immune-modulation. Biomaterials Science. PMID 36994921 DOI: 10.1039/d2bm01804g  0.217
2024 Williamson GL, Bachelder EM, Ainslie KM. Clinical and Preclinical Methods of Heat-Stabilization of Human Vaccines. Molecular Pharmaceutics. PMID 38288698 DOI: 10.1021/acs.molpharmaceut.3c00844  0.217
2021 Varma DM, Redding EA, Bachelder EM, Ainslie KM. Nano- and Microformulations to Advance Therapies for Visceral Leishmaniasis. Acs Biomaterials Science & Engineering. 7: 1725-1741. PMID 33966377 DOI: 10.1021/acsbiomaterials.0c01132  0.217
2024 Ontiveros-Padilla L, Bachelder EM, Ainslie KM. Microparticle and nanoparticle-based influenza vaccines. Journal of Controlled Release : Official Journal of the Controlled Release Society. 376: 880-898. PMID 39427775 DOI: 10.1016/j.jconrel.2024.10.031  0.215
2021 Johnson BM, Uchimura T, Gallovic MD, Thamilarasan M, Chou WC, Gibson SA, Deng M, Tam JW, Batty CJ, Williams J, Matsushima GK, Bachelder EM, Ainslie KM, Markovic-Plese S, Ting JP. STING Agonist Mitigates Experimental Autoimmune Encephalomyelitis by Stimulating Type I IFN-Dependent and -Independent Immune-Regulatory Pathways. Journal of Immunology (Baltimore, Md. : 1950). PMID 33820855 DOI: 10.4049/jimmunol.2001317  0.215
2024 Zhang X, Shi H, Hendy DA, Bachelder EM, Ainslie KM, Ross TM. Multi-COBRA hemagglutinin formulated with cGAMP microparticles elicit protective immune responses against influenza viruses. Biorxiv : the Preprint Server For Biology. PMID 38464191 DOI: 10.1101/2024.02.27.582355  0.214
2022 Watkins-Schulz R, Batty CJ, Stiepel RT, Schmidt ME, Sandor AM, Chou WC, Ainslie KM, Bachelder EM, Ting JP. Microparticle Delivery of a STING Agonist Enables Indirect Activation of NK Cells by Antigen-Presenting Cells. Molecular Pharmaceutics. PMID 35913984 DOI: 10.1021/acs.molpharmaceut.2c00207  0.211
2020 Iweala OI, Choudhary SK, Addison CT, Batty CJ, Kapita CM, Amelio C, Schuyler AJ, Deng S, Bachelder EM, Ainslie KM, Savage PB, Brennan PJ, Commins SP. Glycolipid-Mediated Basophil Activation in Alpha-Gal Allergy. The Journal of Allergy and Clinical Immunology. PMID 32088306 DOI: 10.1016/J.Jaci.2020.02.006  0.209
2023 Hendy DA, Pena ES, Ontiveros-Padilla L, Dixon TA, Middleton DD, Williamson GL, Lukesh NR, Simpson SR, Stiepel RT, Islam MJ, Carlock MA, Ross TM, Bachelder EM, Ainslie KM. Immunogenicity of an adjuvanted broadly active influenza vaccine in immunocompromised and diverse populations. Bioengineering & Translational Medicine. 9: e10634. PMID 38435811 DOI: 10.1002/btm2.10634  0.206
2022 Gallovic MD, Junkins RD, Sandor AM, Pena ES, Sample CJ, Mason AK, Arwood LC, Sahm RA, Bachelder EM, Ainslie KM, Sempowski GD, Ting JP. STING agonist-containing microparticles improve seasonal influenza vaccine efficacy and durability in ferrets over standard adjuvant. Journal of Controlled Release : Official Journal of the Controlled Release Society. 347: 356-368. PMID 35569585 DOI: 10.1016/j.jconrel.2022.05.017  0.205
2020 Batty CJ, Heise MT, Bachelder EM, Ainslie KM. Vaccine formulations in clinical development for the prevention of severe acute respiratory syndrome coronavirus 2 infection. Advanced Drug Delivery Reviews. PMID 33316346 DOI: 10.1016/j.addr.2020.12.006  0.203
2021 Batty CJ, Bachelder EM, Ainslie KM. Historical Perspective of Clinical Nano and Microparticle Formulations for Delivery of Therapeutics. Trends in Molecular Medicine. 27: 516-519. PMID 33903019 DOI: 10.1016/j.molmed.2021.04.002  0.197
2021 Zahid MSH, Varma DM, Johnson MM, Landavazo A, Bachelder EM, Blough BE, Ainslie KM. Overcoming reduced antibiotic susceptibility in intracellular Salmonella enterica serovar Typhimurium using AR-12. Fems Microbiology Letters. PMID 34089315 DOI: 10.1093/femsle/fnab062  0.181
2024 Hendy DA, Ma Y, Dixon TA, Murphy CT, Pena ES, Carlock MA, Ross TM, Bachelder EM, Ainslie KM, Fenton OS. Polymeric cGAMP microparticles affect the immunogenicity of a broadly active influenza mRNA lipid nanoparticle vaccine. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 38844178 DOI: 10.1016/j.jconrel.2024.06.007  0.179
2022 McNamara N, Saunders E, Varghese S, Zheng R, Simpson K, Varma DM, Johnson MM, Hasan Zahid MS, Bachelder EM, Ainslie KM, No JH, Koh D, Shum D, Das N, Patra B, et al. Hit-to-lead optimization of novel phenyl imidazole carboxamides that are active against Leishmania donovani. European Journal of Medicinal Chemistry. 240: 114577. PMID 35810535 DOI: 10.1016/j.ejmech.2022.114577  0.156
2021 Genito CJ, Eckshtain-Levi M, Piedra-Quintero ZL, Krovi SA, Kroboth A, Stiepel RT, Guerau-de-Arellano M, Bachelder EM, Ainslie KM. Dexamethasone and Fumaric Acid Ester Conjugate Synergistically Inhibits Inflammation and NF-κB in Macrophages. Bioconjugate Chemistry. PMID 34165285 DOI: 10.1021/acs.bioconjchem.1c00200  0.155
2022 Jasiewicz NE, Mei KC, Oh HM, Chansoria P, Hendy DA, Bonacquisti EE, Bachelder EM, Ainslie KM, Yin H, Qian L, Jensen BC, Nguyen J. ZipperCells Exhibit Enhanced Accumulation and Retention at the Site of Myocardial Infarction. Advanced Healthcare Materials. e2201094. PMID 36349814 DOI: 10.1002/adhm.202201094  0.149
2017 Webb LM, Amici SA, Jablonski KA, Savardekar H, Panfil AR, Li L, Zhou W, Peine K, Karkhanis V, Bachelder EM, Ainslie KM, Green PL, Li C, Baiocchi RA, Guerau-de-Arellano M. Correction: PRMT5-Selective Inhibitors Suppress Inflammatory T Cell Responses and Experimental Autoimmune Encephalomyelitis. Journal of Immunology (Baltimore, Md. : 1950). 199: 3004. PMID 29018151 DOI: 10.4049/jimmunol.1701237  0.14
2011 Liang JO, Abata K, Bachelder E, Bartley B, Bozadjieva N, Caskey V, Christianson B, Detienne S, Dillon C, Ecklund D, Eckwright D, Erickson R, Fadness T, Fealey M, Fetter N, et al. Original research in the classroom: why do zebrafish spawn in the morning? Zebrafish. 8: 191-202. PMID 22181662 DOI: 10.1089/zeb.2011.0715  0.034
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