Ian J. Mohr, PhD - Publications

Affiliations: 
Microbiology New York University, New York, NY, United States 
Area:
herpes virus, PKR signalling, translational control, viral genetics, latency
Website:
http://www.med.nyu.edu/biosketch/mohri01/publications

98 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Ouwendijk WJD, Roychoudhury P, Cunningham AL, Jerome KR, Koelle DM, Kinchington PR, Mohr I, Wilson AC, Verjans GGMGM, Depledge DP. Reanalysis of single-cell RNA sequencing data does not support herpes simplex virus 1 latency in non-neuronal ganglionic cells in mice. Journal of Virology. e0185823. PMID 38445887 DOI: 10.1128/jvi.01858-23  0.381
2023 Burgess HM, Grande R, Riccio S, Dinesh I, Winkler GS, Depledge DP, Mohr I. CCR4-NOT differentially controls host versus virus poly(a)-tail length and regulates HCMV infection. Embo Reports. 24: e56327. PMID 37846490 DOI: 10.15252/embr.202256327  0.419
2023 Ouwendijk WJD, Roychoudhury P, Cunningham AL, Jerome KR, Koelle DM, Kinchington PR, Mohr I, Wilson AC, Verjans GMGM, Depledge DP. Reanalysis of single-cell RNA sequencing data does not support herpes simplex virus 1 latency in non-neuronal ganglionic cells in mice. Biorxiv : the Preprint Server For Biology. PMID 37503290 DOI: 10.1101/2023.07.17.549345  0.339
2023 Sanders LS, Comar CE, Srinivas KP, Lalli J, Salnikov M, Lengyel J, Southern P, Mohr I, Wilson AC, Rice SA. Herpes Simplex Virus-1 ICP27 Nuclear Export Signal Mutants Exhibit Cell Type-Dependent Deficits in Replication and ICP4 Expression. Journal of Virology. e0195722. PMID 37310267 DOI: 10.1128/jvi.01957-22  0.501
2022 Wilson AC, Mohr I. Control of animal virus replication by RNA adenosine methylation. Advances in Virus Research. 112: 87-114. PMID 35840182 DOI: 10.1016/bs.aivir.2022.01.002  0.328
2022 Thompson L, Depledge DP, Burgess HM, Mohr I. An eIF3d-dependent switch regulates HCMV replication by remodeling the infected cell translation landscape to mimic chronic ER stress. Cell Reports. 39: 110767. PMID 35508137 DOI: 10.1016/j.celrep.2022.110767  0.502
2022 Ly M, Burgess HM, Shah SB, Mohr I, Glaunsinger BA. Vaccinia virus D10 has broad decapping activity that is regulated by mRNA splicing. Plos Pathogens. 18: e1010099. PMID 35202449 DOI: 10.1371/journal.ppat.1010099  0.358
2022 Burgess HM, Vink EI, Mohr I. Minding the message: tactics controlling RNA decay, modification, and translation in virus-infected cells. Genes & Development. 36: 108-132. PMID 35193946 DOI: 10.1101/gad.349276.121  0.468
2021 Hu HL, Srinivas KP, Wang S, Chao MV, Lionnet T, Mohr I, Wilson AC, Depledge DP, Huang TT. Single-cell transcriptomics identifies Gadd45b as a regulator of herpesvirus-reactivating neurons. Embo Reports. e53543. PMID 34842321 DOI: 10.15252/embr.202153543  0.626
2021 Vink EI, Andrews J, Duffy C, Mohr I. Preventing translational inhibition from ribosomal protein insufficiency by a herpes simplex virus-encoded ribosome-associated protein. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34725147 DOI: 10.1073/pnas.2025546118  0.549
2021 Srinivas KP, Depledge DP, Abebe JS, Rice SA, Mohr I, Wilson AC. Widespread remodeling of the mA RNA-modification landscape by a viral regulator of RNA processing and export. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34282019 DOI: 10.1073/pnas.2104805118  0.424
2021 Burgess HM, Depledge DP, Thompson L, Srinivas KP, Grande RC, Vink EI, Abebe JS, Blackaby WP, Hendrick A, Albertella MR, Kouzarides T, Stapleford KA, Wilson AC, Mohr I. Targeting the mA RNA modification pathway blocks SARS-CoV-2 and HCoV-OC43 replication. Genes & Development. PMID 34168039 DOI: 10.1101/gad.348320.121  0.346
2020 Hu HL, Srinivas KP, Mohr I, Huang TT, Wilson AC. Using Primary SCG Neuron Cultures to Study Molecular Determinants of HSV-1 Latency and Reactivation. Methods in Molecular Biology (Clifton, N.J.). 2060: 263-277. PMID 31617183 DOI: 10.1007/978-1-4939-9814-2_14  0.449
2019 Rubio RM, Mohr I. Inhibition of ULK1 and Beclin1 by an α-herpesvirus Akt-like Ser/Thr kinase limits autophagy to stimulate virus replication. Proceedings of the National Academy of Sciences of the United States of America. 116: 26941-26950. PMID 31843932 DOI: 10.1073/Pnas.1915139116  0.609
2019 Bianco C, Mohr I. Ribosome biogenesis restricts innate immune responses to virus infection and DNA. Elife. 8. PMID 31841110 DOI: 10.7554/Elife.49551  0.561
2019 Bianco C, Thompson L, Mohr I. Repression of eEF2K transcription by NF-κB tunes translation elongation to inflammation and dsDNA-sensing. Proceedings of the National Academy of Sciences of the United States of America. PMID 31636182 DOI: 10.1073/Pnas.1909143116  0.448
2019 Hu HL, Shiflett LA, Kobayashi M, Chao MV, Wilson AC, Mohr I, Huang TT. TOP2β-Dependent Nuclear DNA Damage Shapes Extracellular Growth Factor Responses via Dynamic AKT Phosphorylation to Control Virus Latency. Molecular Cell. PMID 30930055 DOI: 10.1016/J.Molcel.2019.02.032  0.697
2019 Depledge DP, Srinivas KP, Sadaoka T, Bready D, Mori Y, Placantonakis DG, Mohr I, Wilson AC. Direct RNA sequencing on nanopore arrays redefines the transcriptional complexity of a viral pathogen. Nature Communications. 10: 754. PMID 30765700 DOI: 10.1038/S41467-019-08734-9  0.41
2019 Bianco C, Mohr I. Author response: Ribosome biogenesis restricts innate immune responses to virus infection and DNA Elife. DOI: 10.7554/Elife.49551.Sa2  0.416
2018 Rubio RM, Depledge DP, Bianco C, Thompson L, Mohr I. RNA mA modification enzymes shape innate responses to DNA by regulating interferon β. Genes & Development. PMID 30463905 DOI: 10.1101/Gad.319475.118  0.455
2018 Depledge DP, Mohr I, Wilson AC. Going the distance: optimizing RNA-Seq strategies for transcriptomic analysis of complex viral genomes. Journal of Virology. PMID 30305358 DOI: 10.1128/Jvi.01342-18  0.371
2018 Vink EI, Lee S, Smiley JR, Mohr I. Remodeling mTORC1 responsiveness to amino acids by the herpes simplex virus UL46 and Us3 gene products supports replication during nutrient insufficiency. Journal of Virology. PMID 30282708 DOI: 10.1128/Jvi.01377-18  0.515
2018 Stern-Ginossar N, Thompson SR, Mathews MB, Mohr I. Translational Control in Virus-Infected Cells. Cold Spring Harbor Perspectives in Biology. PMID 29891561 DOI: 10.1101/Cshperspect.A033001  0.559
2018 Burgess HM, Pourchet A, Hajdu CH, Chiriboga L, Frey AB, Mohr I. Targeting Poxvirus Decapping Enzymes and mRNA Decay to Generate an Effective Oncolytic Virus. Molecular Therapy Oncolytics. 8: 71-81. PMID 29888320 DOI: 10.1016/J.Omto.2018.01.001  0.451
2018 Burgess HM, Mohr I. Defining the Role of Stress Granules in Innate Immune Suppression by the Herpes Simplex Virus 1 Endoribonuclease VHS. Journal of Virology. 92. PMID 29793959 DOI: 10.1128/Jvi.00829-18  0.615
2017 Pourchet A, Copin R, Mulvey MC, Shopsin B, Mohr I, Wilson AC. Shared ancestry of herpes simplex virus 1 strain Patton with recent clinical isolates from Asia and with strain KOS63. Virology. 512: 124-131. PMID 28957690 DOI: 10.1016/J.Virol.2017.09.016  0.783
2017 Pourchet A, Modrek AS, Placantonakis DG, Mohr I, Wilson AC. Modeling HSV-1 Latency in Human Embryonic Stem Cell-Derived Neurons. Pathogens (Basel, Switzerland). 6. PMID 28594343 DOI: 10.3390/Pathogens6020024  0.531
2017 Vink EI, Smiley JR, Mohr I. Subversion of host responses to energy insufficiency by Us3 supports HSV-1 replication during stress. Journal of Virology. PMID 28468873 DOI: 10.1128/Jvi.00295-17  0.531
2017 Bianco C, Mohr I. Restriction of HCMV replication by ISG15, a host effector regulated by cGAS-STING dsDNA sensing. Journal of Virology. PMID 28202760 DOI: 10.1128/Jvi.02483-16  0.591
2017 Linderman JA, Kobayashi M, Rayannavar V, Fak JJ, Darnell RB, Chao MV, Wilson AC, Mohr I. Immune Escape via a Transient Gene Expression Program Enables Productive Replication of a Latent Pathogen. Cell Reports. 18: 1312-1323. PMID 28147283 DOI: 10.1016/J.Celrep.2017.01.017  0.722
2016 Mohr I. Closing in on the causes of host shutoff. Elife. 5. PMID 27644108 DOI: 10.7554/Elife.20755  0.479
2016 Jan E, Mohr I, Walsh D. A Cap-to-Tail Guide to mRNA Translation Strategies in Virus-Infected Cells Annual Review of Virology. 3: 283-307. PMID 27501262 DOI: 10.1146/Annurev-Virology-100114-055014  0.567
2016 Pourchet A, Fuhrmann SR, Pilones KA, Demaria S, Frey AB, Mulvey M, Mohr I. CD8(+) T-cell Immune Evasion Enables Oncolytic Virus Immunotherapy. Ebiomedicine. 5: 59-67. PMID 27077112 DOI: 10.1016/J.Ebiom.2016.01.022  0.738
2016 Burgess HM, Mohr I. Evolutionary clash between myxoma virus and rabbit PKR in Australia. Proceedings of the National Academy of Sciences of the United States of America. PMID 27035991 DOI: 10.1073/Pnas.1602063113  0.511
2016 Ager C, Reilley M, Nicholas C, Bartkowiak T, Jaiswal A, Curran M, Albershardt TC, Bajaj A, Archer JF, Reeves RS, Ngo LY, Berglund P, ter Meulen J, Denis C, Ghadially H, ... ... Mohr I, et al. 31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part two Journal For Immunotherapy of Cancer. 4. DOI: 10.1186/S40425-016-0173-6  0.668
2015 Mattila RK, Harila K, Kangas SM, Paavilainen H, Heape AM, Mohr IJ, Hukkanen V. An investigation of herpes simplex virus type 1 latency in a novel mouse dorsal root ganglion model suggests a role for ICP34.5 in reactivation. The Journal of General Virology. PMID 25854552 DOI: 10.1099/Vir.0.000138  0.543
2015 Burgess HM, Mohr I. Cellular 5′-3′ mRNA Exonuclease Xrn1 Controls Double-Stranded RNA Accumulation and Anti-Viral Responses Cell Host & Microbe. 17: 332-344. PMID 25766294 DOI: 10.1016/J.Chom.2015.02.003  0.537
2015 Pourchet A, Fuhrmann SR, Pilones KA, Demaria S, Frey AB, Mulvey M, Mohr I. CD8+ T-cell Immune Evasion Enables Oncolytic Virus Immunotherapy Ebiomedicine. DOI: 10.1016/j.ebiom.2016.01.022  0.718
2014 McKinney C, Zavadil J, Bianco C, Shiflett L, Brown S, Mohr I. Global Reprogramming of the Cellular Translational Landscape Facilitates Cytomegalovirus Replication. Cell Reports. 6: 1175. PMID 28898682 DOI: 10.1016/j.celrep.2014.03.002  0.643
2014 Karttunen H, Savas JN, McKinney C, Chen YH, Yates JR, Hukkanen V, Huang TT, Mohr I. Co-opting the Fanconi anemia genomic stability pathway enables herpesvirus DNA synthesis and productive growth. Molecular Cell. 55: 111-22. PMID 24954902 DOI: 10.1016/J.Molcel.2014.05.020  0.701
2014 Walsh D, Mohr I. Coupling 40S ribosome recruitment to modification of a cap-binding initiation factor by eIF3 subunit e Genes & Development. 28: 835-840. PMID 24736843 DOI: 10.1101/Gad.236752.113  0.401
2014 Kim JY, Shiflett LA, Linderman JA, Mohr I, Wilson AC. Using homogeneous primary neuron cultures to study fundamental aspects of HSV-1 latency and reactivation. Methods in Molecular Biology (Clifton, N.J.). 1144: 167-79. PMID 24671683 DOI: 10.1007/978-1-4939-0428-0_11  0.451
2014 McKinney C, Zavadil J, Bianco C, Shiflett L, Brown S, Mohr I. Global reprogramming of the cellular translational landscape facilitates cytomegalovirus replication. Cell Reports. 6: 9-17. PMID 24373965 DOI: 10.1016/J.Celrep.2013.11.045  0.721
2014 McKinney C, Zavadil J, Bianco C, Shiflett L, Brown S, Mohr I. Global Reprogramming of the Cellular Translational Landscape Facilitates Cytomegalovirus Replication Cell Reports. 6: 1175. DOI: 10.1016/j.celrep.2014.03.002  0.643
2013 Kew C, Lui PY, Chan CP, Liu X, Au SW, Mohr I, Jin DY, Kok KH. Suppression of PACT-induced type I interferon production by herpes simplex virus 1 Us11 protein. Journal of Virology. 87: 13141-9. PMID 24067967 DOI: 10.1128/Jvi.02564-13  0.549
2013 McKinney C, Yu D, Mohr I. A new role for the cellular PABP repressor Paip2 as an innate restriction factor capable of limiting productive cytomegalovirus replication Genes & Development. 27: 1809-1820. PMID 23964095 DOI: 10.1101/Gad.221341.113  0.767
2013 Walsh D, Mathews MB, Mohr I. Tinkering with translation: protein synthesis in virus-infected cells. Cold Spring Harbor Perspectives in Biology. 5: a012351. PMID 23209131 DOI: 10.1101/Cshperspect.A012351  0.578
2012 Mohr I, Sonenberg N. Host translation at the nexus of infection and immunity. Cell Host & Microbe. 12: 470-83. PMID 23084916 DOI: 10.1016/J.Chom.2012.09.006  0.42
2012 Wilson AC, Mohr I. A cultured affair: HSV latency and reactivation in neurons. Trends in Microbiology. 20: 604-11. PMID 22963857 DOI: 10.1016/J.Tim.2012.08.005  0.464
2012 Kobayashi M, Arias C, Garabedian A, Palmenberg AC, Mohr I. Site-specific cleavage of the host poly(A) binding protein by the encephalomyocarditis virus 3C proteinase stimulates viral replication. Journal of Virology. 86: 10686-94. PMID 22837200 DOI: 10.1128/Jvi.00896-12  0.741
2012 Kobayashi M, Wilson AC, Chao MV, Mohr I. Control of viral latency in neurons by axonal mTOR signaling and the 4E-BP translation repressor. Genes & Development. 26: 1527-32. PMID 22802527 DOI: 10.1101/Gad.190157.112  0.648
2012 Chuluunbaatar U, Roller R, Mohr I. Suppression of extracellular signal-regulated kinase activity in herpes simplex virus 1-infected cells by the Us3 protein kinase. Journal of Virology. 86: 7771-6. PMID 22593153 DOI: 10.1128/Jvi.00622-12  0.828
2012 Herdy B, Jaramillo M, Svitkin YV, Rosenfeld AB, Kobayashi M, Walsh D, Alain T, Sean P, Robichaud N, Topisirovic I, Furic L, Dowling RJ, Sylvestre A, Rong L, Colina R, ... ... Mohr I, et al. Translational control of the activation of transcription factor NF-κB and production of type I interferon by phosphorylation of the translation factor eIF4E. Nature Immunology. 13: 543-50. PMID 22544393 DOI: 10.1038/Ni.2291  0.611
2012 Kobayashi M, Kim JY, Camarena V, Roehm PC, Chao MV, Wilson AC, Mohr I. A primary neuron culture system for the study of herpes simplex virus latency and reactivation. Journal of Visualized Experiments : Jove. PMID 22491318 DOI: 10.3791/3823  0.826
2012 McKinney C, Perez C, Mohr I. Poly(A) binding protein abundance regulates eukaryotic translation initiation factor 4F assembly in human cytomegalovirus-infected cells. Proceedings of the National Academy of Sciences of the United States of America. 109: 5627-32. PMID 22431630 DOI: 10.1073/Pnas.1202829109  0.796
2012 Kim JY, Mandarino A, Chao MV, Mohr I, Wilson AC. Transient reversal of episome silencing precedes VP16-dependent transcription during reactivation of latent HSV-1 in neurons. Plos Pathogens. 8: e1002540. PMID 22383875 DOI: 10.1371/Journal.Ppat.1002540  0.698
2012 Kuhn MA, Nayak S, Camarena V, Gardner J, Wilson A, Mohr I, Chao MV, Roehm PC. A cell culture model of facial palsy resulting from reactivation of latent herpes simplex type 1. Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology. 33: 87-92. PMID 22158020 DOI: 10.1097/Mao.0B013E31823Dbb20  0.803
2012 Xi X, Persson LM, O'Brien MW, Mohr I, Wilson AC. Cooperation between viral interferon regulatory factor 4 and RTA to activate a subset of Kaposi's sarcoma-associated herpesvirus lytic promoters. Journal of Virology. 86: 1021-33. PMID 22090118 DOI: 10.1128/Jvi.00694-11  0.468
2011 Walsh D, Mohr I. Viral subversion of the host protein synthesis machinery. Nature Reviews Microbiology. 9: 860-875. PMID 22002165 DOI: 10.1038/Nrmicro2655  0.572
2011 Roehm PC, Camarena V, Nayak S, Gardner JB, Wilson A, Mohr I, Chao MV. Cultured vestibular ganglion neurons demonstrate latent HSV1 reactivation. The Laryngoscope. 121: 2268-75. PMID 21898423 DOI: 10.1002/Lary.22035  0.796
2011 Gao N, Shang J, Huynh D, Manthati VL, Arias C, Harding HP, Kaufman RJ, Mohr I, Ron D, Falck JR, Lehrman MA. Mannose-6-phosphate regulates destruction of lipid-linked oligosaccharides. Molecular Biology of the Cell. 22: 2994-3009. PMID 21737679 DOI: 10.1091/Mbc.E11-04-0286  0.616
2011 Chuluunbaatar U, Mohr I. A herpesvirus kinase that masquerades as Akt: you don't have to look like Akt, to act like it. Cell Cycle (Georgetown, Tex.). 10: 2064-8. PMID 21606676 DOI: 10.4161/Cc.10.13.16242  0.833
2011 Perez C, McKinney C, Chulunbaatar U, Mohr I. Translational Control of the Abundance of Cytoplasmic Poly(A) Binding Protein in Human Cytomegalovirus-Infected Cells Journal of Virology. 85: 156-164. PMID 20980505 DOI: 10.1128/Jvi.01778-10  0.817
2010 Chuluunbaatar U, Roller R, Feldman ME, Brown S, Shokat KM, Mohr I. Constitutive mTORC1 activation by a herpesvirus Akt surrogate stimulates mRNA translation and viral replication. Genes & Development. 24: 2627-39. PMID 21123650 DOI: 10.1101/Gad.1978310  0.832
2010 Camarena V, Kobayashi M, Kim JY, Roehm P, Perez R, Gardner J, Wilson AC, Mohr I, Chao MV. Nature and duration of growth factor signaling through receptor tyrosine kinases regulates HSV-1 latency in neurons. Cell Host & Microbe. 8: 320-30. PMID 20951966 DOI: 10.1016/J.Chom.2010.09.007  0.817
2009 Arias C, Walsh D, Harbell J, Wilson AC, Mohr I. Activation of host translational control pathways by a viral developmental switch. Plos Pathogens. 5: e1000334. PMID 19300492 DOI: 10.1371/Journal.Ppat.1000334  0.71
2008 Walsh D, Arias C, Perez C, Halladin D, Escandon M, Ueda T, Watanabe-Fukunaga R, Fukunaga R, Mohr I. Eukaryotic translation initiation factor 4F architectural alterations accompany translation initiation factor redistribution in poxvirus-infected cells. Molecular and Cellular Biology. 28: 2648-58. PMID 18250159 DOI: 10.1128/Mcb.01631-07  0.739
2007 Sànchez R, Mohr I. Inhibition of Cellular 2′-5′ Oligoadenylate Synthetase by the Herpes Simplex Virus Type 1 Us11 Protein Journal of Virology. 81: 3455-3464. PMID 17229694 DOI: 10.1128/Jvi.02520-06  0.647
2007 Mulvey M, Arias C, Mohr I. Maintenance of endoplasmic reticulum (ER) homeostasis in herpes simplex virus type 1-infected cells through the association of a viral glycoprotein with PERK, a cellular ER stress sensor. Journal of Virology. 81: 3377-90. PMID 17229688 DOI: 10.1128/Jvi.02191-06  0.838
2007 Campbell SA, Mulvey M, Mohr I, Gromeier M. Attenuation of herpes simplex virus neurovirulence with picornavirus cis-acting genetic elements. Journal of Virology. 81: 791-9. PMID 17079296 DOI: 10.1128/Jvi.00714-06  0.804
2007 Mohr IJ, Pe’ery T, Mathews MB. 20 Protein Synthesis and Translational Control during Viral Infection Cold Spring Harbor Monograph Archive. 48: 545-599. DOI: 10.1101/087969767.48.545  0.57
2006 Mulvey M, Arias C, Mohr I. Resistance of mRNA translation to acute endoplasmic reticulum stress-inducing agents in herpes simplex virus type 1-infected cells requires multiple virus-encoded functions. Journal of Virology. 80: 7354-63. PMID 16840316 DOI: 10.1128/Jvi.00479-06  0.832
2006 Mohr I. Phosphorylation and dephosphorylation events that regulate viral mRNA translation Virus Research. 119: 89-99. PMID 16305812 DOI: 10.1016/J.Virusres.2005.10.009  0.566
2005 Mohr I. To replicate or not to replicate: achieving selective oncolytic virus replication in cancer cells through translational control. Oncogene. 24: 7697-7709. PMID 16299530 DOI: 10.1038/Sj.Onc.1209053  0.564
2005 Walsh D, Perez C, Notary J, Mohr I. Regulation of the Translation Initiation Factor eIF4F by Multiple Mechanisms in Human Cytomegalovirus-Infected Cells Journal of Virology. 79: 8057-8064. PMID 15956551 DOI: 10.1128/Jvi.79.13.8057-8064.2005  0.723
2004 Mulvey M, Camarena V, Mohr I. Full resistance of herpes simplex virus type 1-infected primary human cells to alpha interferon requires both the Us11 and gamma(1)34.5 gene products. Journal of Virology. 78: 10193-6. PMID 15331752 DOI: 10.1128/Jvi.78.18.10193-10196.2004  0.822
2004 Walsh D, Mohr I. Phosphorylation of eIF4E by Mnk-1 enhances HSV-1 translation and replication in quiescent cells. Genes & Development. 18: 660-72. PMID 15075293 DOI: 10.1101/GAD.1185304  0.556
2004 Mohr I. Neutralizing innate host defenses to control viral translation in HSV-1 infected cells. International Reviews of Immunology. 23: 199-220. PMID 14690861 DOI: 10.1080/08830180490265600  0.645
2003 Mulvey M, Poppers J, Sternberg D, Mohr I. Regulation of eIF2alpha phosphorylation by different functions that act during discrete phases in the herpes simplex virus type 1 life cycle. Journal of Virology. 77: 10917-28. PMID 14512542 DOI: 10.1128/Jvi.77.20.10917-10928.2003  0.848
2003 Benboudjema L, Mulvey M, Gao Y, Pimplikar SW, Mohr I. Association of the herpes simplex virus type 1 Us11 gene product with the cellular kinesin light-chain-related protein PAT1 results in the redistribution of both polypeptides. Journal of Virology. 77: 9192-203. PMID 12915535 DOI: 10.1128/Jvi.77.17.9192-9203.2003  0.806
2003 Mohr I. Genetic metamorphosis of herpes simplex virus-1 into a biological therapeutic for human cancer Expert Opinion On Biological Therapy. 3: 113-125. PMID 12718736 DOI: 10.1517/14712598.3.1.113  0.478
2003 Ward SL, Scheuner D, Poppers J, Kaufman RJ, Mohr I, Leib DA. In vivo replication of an ICP34.5 second-site suppressor mutant following corneal infection correlates with in vitro regulation of eIF2 alpha phosphorylation. Journal of Virology. 77: 4626-34. PMID 12663769 DOI: 10.1128/Jvi.77.8.4626-4634.2003  0.841
2003 Schneider RJ, Mohr I. Translation initiation and viral tricks. Trends in Biochemical Sciences. 28: 130-6. PMID 12633992 DOI: 10.1016/S0968-0004(03)00029-X  0.516
2003 Poppers J, Mulvey M, Perez C, Khoo D, Mohr I. Identification of a Lytic-Cycle Epstein-Barr Virus Gene Product That Can Regulate PKR Activation Journal of Virology. 77: 228-236. PMID 12477828 DOI: 10.1128/Jvi.77.1.228-236.2003  0.822
2002 Khoo D, Perez C, Mohr I. Characterization of RNA Determinants Recognized by the Arginine- and Proline-Rich Region of Us11, a Herpes Simplex Virus Type 1-Encoded Double-Stranded RNA Binding Protein That Prevents PKR Activation Journal of Virology. 76: 11971-11981. PMID 12414939 DOI: 10.1128/Jvi.76.23.11971-11981.2002  0.604
2002 Peters GA, Khoo D, Mohr I, Sen GC. Inhibition of PACT-mediated activation of PKR by the herpes simplex virus type 1 Us11 protein. Journal of Virology. 76: 11054-64. PMID 12368348 DOI: 10.1128/Jvi.76.21.11054-11064.2002  0.492
2001 Taneja S, MacGregor J, Markus S, Ha S, Mohr I. Enhanced antitumor efficacy of a herpes simplex virus mutant isolated by genetic selection in cancer cells. Proceedings of the National Academy of Sciences of the United States of America. 98: 8804-8. PMID 11438715 DOI: 10.1073/Pnas.161011798  0.48
2001 Mohr I, Sternberg D, Ward S, Leib D, Mulvey M, Gluzman Y. A herpes simplex virus type 1 gamma34.5 second-site suppressor mutant that exhibits enhanced growth in cultured glioblastoma cells is severely attenuated in animals. Journal of Virology. 75: 5189-96. PMID 11333900 DOI: 10.1128/Jvi.75.11.5189-5196.2001  0.781
2000 Poppers J, Mulvey M, Khoo D, Mohr I. Inhibition of PKR Activation by the Proline-Rich RNA Binding Domain of the Herpes Simplex Virus Type 1 Us11 Protein Journal of Virology. 74: 11215-11221. PMID 11070019 DOI: 10.1128/Jvi.74.23.11215-11221.2000  0.832
1999 Mulvey M, Poppers J, Ladd A, Mohr I. A Herpesvirus Ribosome-Associated, RNA-Binding Protein Confers a Growth Advantage upon Mutants Deficient in a GADD34-Related Function Journal of Virology. 73: 3375-3385. PMID 10074192 DOI: 10.1128/Jvi.73.4.3375-3385.1999  0.849
1997 He B, Chou J, Brandimarti R, Mohr I, Gluzman Y, Roizman B. Suppression of the phenotype of gamma(1)34.5- herpes simplex virus 1: failure of activated RNA-dependent protein kinase to shut off protein synthesis is associated with a deletion in the domain of the alpha47 gene. Journal of Virology. 71: 6049-54. PMID 9223497 DOI: 10.1128/Jvi.71.8.6049-6054.1997  0.455
1994 Park P, Copeland W, Yang L, Wang T, Botchan MR, Mohr IJ. The cellular DNA polymerase alpha-primase is required for papillomavirus DNA replication and associates with the viral E1 helicase. Proceedings of the National Academy of Sciences of the United States of America. 91: 8700-4. PMID 8078945 DOI: 10.1073/Pnas.91.18.8700  0.443
1993 Yang L, Mohr I, Fouts E, Lim DA, Nohaile M, Botchan M. The E1 protein of bovine papilloma virus 1 is an ATP-dependent DNA helicase. Proceedings of the National Academy of Sciences of the United States of America. 90: 5086-90. PMID 8389467 DOI: 10.1073/Pnas.90.11.5086  0.381
1993 Lentz MR, Pak D, Mohr I, Botchan MR. The E1 replication protein of bovine papillomavirus type 1 contains an extended nuclear localization signal that includes a p34cdc2 phosphorylation site. Journal of Virology. 67: 1414-23. PMID 8382303 DOI: 10.1128/Jvi.67.3.1414-1423.1993  0.396
1992 Maulbecker C, Mohr I, Gluzman Y, Bartholomew J, Botchan M. A deletion in the simian virus 40 large T antigen impairs lytic replication in monkey cells in vivo but enhances DNA replication in vitro: New complementation function of T antigen Journal of Virology. 66: 2195-2207. PMID 1312627 DOI: 10.1128/Jvi.66.4.2195-2207.1992  0.466
1991 Yang L, Li R, Mohr IJ, Clark R, Botchan MR. Activation of BPV-1 replication in vitro by the transcription factor E2. Nature. 353: 628-32. PMID 1656277 DOI: 10.1038/353628A0  0.338
1990 Mohr IJ, Clark R, Sun S, Androphy EJ, MacPherson P, Botchan MR. Targeting the E1 replication protein to the papillomavirus origin of replication by complex formation with the E2 transactivator. Science (New York, N.Y.). 250: 1694-9. PMID 2176744 DOI: 10.1126/Science.2176744  0.306
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