| Year |
Citation |
Score |
| 2024 |
Crooke AM, Chand AK, Balskus EP. Elucidation of chalkophomycin biosynthesis reveals -hydroxypyrrole-forming enzymes. Biorxiv : the Preprint Server For Biology. PMID 38328124 DOI: 10.1101/2024.01.24.577118 |
0.326 |
|
| 2023 |
Nagashima K, Zhao A, Atabakhsh K, Bae M, Blum JE, Weakley A, Jain S, Meng X, Cheng AG, Wang M, Higginbottom S, Dimas A, Murugkar P, Sattely ES, Moon JJ, ... Balskus EP, et al. Mapping the T cell repertoire to a complex gut bacterial community. Nature. PMID 37587342 DOI: 10.1038/s41586-023-06431-8 |
0.679 |
|
| 2023 |
Kountz DJ, Balskus EP. A diversified, widespread microbial gene cluster encodes homologs of methyltransferases involved in methanogenesis. Biorxiv : the Preprint Server For Biology. PMID 37577662 DOI: 10.1101/2023.07.31.551370 |
0.324 |
|
| 2022 |
Martins TP, Glasser NR, Kountz DJ, Oliveira P, Balskus EP, Leão PN. Biosynthesis of the Unusual Carbon Skeleton of Nocuolin A. Acs Chemical Biology. PMID 36044983 DOI: 10.1021/acschembio.2c00464 |
0.606 |
|
| 2021 |
Eusebio N, Rego A, Glasser NR, Castelo-Branco R, Balskus EP, Leão PN. Distribution and diversity of dimetal-carboxylate halogenases in cyanobacteria. Bmc Genomics. 22: 633. PMID 34461836 DOI: 10.1186/s12864-021-07939-x |
0.609 |
|
| 2021 |
Rajakovich LJ, Fu B, Bollenbach M, Balskus EP. Elucidation of an anaerobic pathway for metabolism of l-carnitine-derived γ-butyrobetaine to trimethylamine in human gut bacteria. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34362844 DOI: 10.1073/pnas.2101498118 |
0.773 |
|
| 2021 |
McBride MJ, Pope SR, Hu K, Okafor CD, Balskus EP, Bollinger JM, Boal AK. Structure and assembly of the diiron cofactor in the heme-oxygenase-like domain of the -nitrosourea-producing enzyme SznF. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33468680 DOI: 10.1073/pnas.2015931118 |
0.515 |
|
| 2020 |
Bollenbach M, Ortega M, Orman M, Drennan CL, Balskus EP. Discovery of a Cyclic Choline Analog That Inhibits Anaerobic Choline Metabolism by Human Gut Bacteria. Acs Medicinal Chemistry Letters. 11: 1980-1985. PMID 33062182 DOI: 10.1021/Acsmedchemlett.0C00005 |
0.301 |
|
| 2020 |
McBride M, Sil D, Ng TL, Crooke AM, Kenney GE, Tysoe CR, Zhang B, Balskus EP, Boal AK, Krebs C, Bollinger JM. A peroxodiiron(III) intermediate mediating both -hydroxylation steps in biosynthesis of the -nitrosourea pharmacophore of streptozotocin by SznF. Journal of the American Chemical Society. PMID 32511919 DOI: 10.1021/Jacs.0C03431 |
0.61 |
|
| 2020 |
Bisanz JE, Soto-Perez P, Noecker C, Aksenov AA, Lam KN, Kenney GE, Bess EN, Haiser HJ, Kyaw TS, Yu FB, Rekdal VM, Ha CWY, Devkota S, Balskus EP, Dorrestein PC, et al. A Genomic Toolkit for the Mechanistic Dissection of Intractable Human Gut Bacteria. Cell Host & Microbe. PMID 32348781 DOI: 10.1016/J.Chom.2020.04.006 |
0.465 |
|
| 2019 |
Jiang Y, Stornetta A, Villalta PW, Wilson MR, Boudreau PD, Zha L, Balbo S, Balskus EP. The reactivity of an unusual amidase may explain colibactin's DNA cross-linking activity. Journal of the American Chemical Society. PMID 31251062 DOI: 10.1021/Jacs.9B02453 |
0.735 |
|
| 2019 |
Volpe MR, Wilson MR, Brotherton CA, Winter ES, Johnson SE, Balskus EP. In vitro characterization of the colibactin-activating peptidase ClbP enables development of a fluorogenic activity probe. Acs Chemical Biology. PMID 31059217 DOI: 10.1021/acschembio.9b00069 |
0.374 |
|
| 2019 |
Wilson MR, Jiang Y, Villalta PW, Stornetta A, Boudreau PD, Carrá A, Brennan CA, Chun E, Ngo L, Samson LD, Engelward BP, Garrett WS, Balbo S, Balskus EP. The human gut bacterial genotoxin colibactin alkylates DNA. Science (New York, N.Y.). 363. PMID 30765538 DOI: 10.1126/Science.Aar7785 |
0.732 |
|
| 2019 |
Peck SC, Denger K, Burrichter A, Irwin SM, Balskus EP, Schleheck D. A glycyl radical enzyme enables hydrogen sulfide production by the human intestinal bacterium . Proceedings of the National Academy of Sciences of the United States of America. PMID 30718429 DOI: 10.1073/Pnas.1815661116 |
0.621 |
|
| 2019 |
Schultz EE, Braffman NR, Luescher MU, Hager HH, Balskus EP. Biocatalytic Friedel-Crafts Alkylation Using a Promiscuous Biosynthetic Enzyme. Angewandte Chemie (International Ed. in English). PMID 30706984 DOI: 10.1002/anie.201814016 |
0.55 |
|
| 2019 |
Martins TP, Rouger C, Glasser NR, Freitas S, de Fraissinette NB, Balskus EP, Tasdemir D, Leão PN. Chemistry, bioactivity and biosynthesis of cyanobacterial alkylresorcinols. Natural Product Reports. PMID 30702733 DOI: 10.1039/c8np00080h |
0.613 |
|
| 2018 |
Orman M, Bodea S, Funk MA, Campo AM, Bollenbach M, Drennan CL, Balskus EP. Structure-Guided Identification of a Small Molecule That Inhibits Anaerobic Choline Metabolism by Human Gut Bacteria. Journal of the American Chemical Society. PMID 30557011 DOI: 10.2210/Pdb6Nd3/Pdb |
0.314 |
|
| 2018 |
Rajakovich LJ, Balskus EP. Metabolic functions of the human gut microbiota: the role of metalloenzymes. Natural Product Reports. PMID 30452039 DOI: 10.1039/c8np00074c |
0.754 |
|
| 2018 |
Wang KA, Ng TL, Wang P, Huang Z, Balskus EP, van der Donk WA. Glutamic acid is a carrier for hydrazine during the biosyntheses of fosfazinomycin and kinamycin. Nature Communications. 9: 3687. PMID 30206228 DOI: 10.1038/S41467-018-06083-7 |
0.44 |
|
| 2018 |
Koppel N, Bisanz JE, Pandelia ME, Turnbaugh PJ, Balskus EP. Discovery and characterization of a prevalent human gut bacterial enzyme sufficient for the inactivation of a family of plant toxins. Elife. 7. PMID 29761785 DOI: 10.7554/Elife.33953 |
0.318 |
|
| 2018 |
Dorrestein PC, Balskus EP. Chemical signaling at the eukaryotic/prokaryotic interface. Chemical Society Reviews. PMID 29479607 DOI: 10.1039/C8Cs90021C |
0.358 |
|
| 2018 |
Huang YY, Martínez-Del Campo A, Balskus EP. Anaerobic 4-hydroxyproline utilization: discovery of a new glycyl radical enzyme in the human gut microbiome uncovers a widespread microbial metabolic activity. Gut Microbes. 0. PMID 29405826 DOI: 10.1080/19490976.2018.1435244 |
0.318 |
|
| 2017 |
Zha L, Jiang Y, Henke MT, Wilson MR, Wang JX, Kelleher NL, Balskus EP. Colibactin assembly line enzymes use S-adenosylmethionine to build a cyclopropane ring. Nature Chemical Biology. PMID 28805802 DOI: 10.1038/Nchembio.2448 |
0.525 |
|
| 2017 |
Nakamura H, Schultz EE, Balskus EP. A new strategy for aromatic ring alkylation in cylindrocyclophane biosynthesis. Nature Chemical Biology. PMID 28671684 DOI: 10.1038/nchembio.2421 |
0.549 |
|
| 2017 |
Koppel N, Maini Rekdal V, Balskus EP. Chemical transformation of xenobiotics by the human gut microbiota. Science (New York, N.Y.). 356. PMID 28642381 DOI: 10.1126/science.aag2770 |
0.314 |
|
| 2017 |
Wallace S, Balskus EP. Interfacing Biocompatible Reactions with Engineered Escherichia coli. Methods in Molecular Biology (Clifton, N.J.). 1586: 409-421. PMID 28470621 DOI: 10.1007/978-1-4939-6887-9_27 |
0.508 |
|
| 2017 |
Wilson MR, Zha L, Balskus EP. Natural Product Discovery from the Human Microbiome. The Journal of Biological Chemistry. PMID 28389564 DOI: 10.1074/jbc.R116.762906 |
0.435 |
|
| 2017 |
Wang P, Hong G, Wilson MR, Balskus EP. Production of stealthin C involves an S-N-type Smiles rearrangement. Journal of the American Chemical Society. PMID 28191843 DOI: 10.1021/jacs.6b10586 |
0.408 |
|
| 2017 |
Levin BJ, Huang YY, Peck SC, Wei Y, Martínez-Del Campo A, Marks JA, Franzosa EA, Huttenhower C, Balskus EP. A prominent glycyl radical enzyme in human gut microbiomes metabolizes trans-4-hydroxy-l-proline. Science (New York, N.Y.). 355. PMID 28183913 DOI: 10.1126/Science.Aai8386 |
0.617 |
|
| 2016 |
Leão PN, Nakamura H, Costa M, Pereira AR, Martins R, Vasconcelos V, Gerwick WH, Balskus EP. Corrigendum: Biosynthesis-Assisted Structural Elucidation of the Bartolosides, Chlorinated Aromatic Glycolipids from Cyanobacteria. Angewandte Chemie (International Ed. in English). 55: 14895. PMID 27860179 DOI: 10.1002/anie.201609701 |
0.622 |
|
| 2016 |
Wallace S, Balskus EP. Designer Micelles Accelerate Flux Through Engineered Metabolism in E. coli and Support Biocompatible Chemistry. Angewandte Chemie (International Ed. in English). 55: 6023-7. PMID 27061024 DOI: 10.1002/Anie.201600966 |
0.52 |
|
| 2016 |
Zha L, Wilson MR, Brotherton CA, Balskus EP. Characterization of Polyketide Synthase Machinery from the pks Island Facilitates Isolation of a Candidate Precolibactin. Acs Chemical Biology. PMID 26890481 DOI: 10.1021/acschembio.6b00014 |
0.494 |
|
| 2015 |
Waldman AJ, Pechersky Y, Wang P, Wang JX, Balskus EP. Back Cover: The Cremeomycin Biosynthetic Gene Cluster Encodes a Pathway for Diazo Formation (ChemBioChem 15/2015). Chembiochem : a European Journal of Chemical Biology. 16: 2254. PMID 26444309 DOI: 10.1002/cbic.201500461 |
0.435 |
|
| 2015 |
Medema MH, Kottmann R, Yilmaz P, Cummings M, Biggins JB, Blin K, de Bruijn I, Chooi YH, Claesen J, Coates RC, Cruz-Morales P, Duddela S, Düsterhus S, Edwards DJ, Fewer DP, ... ... Balskus EP, et al. Minimum Information about a Biosynthetic Gene cluster. Nature Chemical Biology. 11: 625-31. PMID 26284661 DOI: 10.1038/Nchembio.1890 |
0.725 |
|
| 2015 |
Waldman AJ, Pechersky Y, Wang P, Wang JX, Balskus EP. The cremeomycin biosynthetic gene cluster encodes a pathway for diazo formation. Chembiochem : a European Journal of Chemical Biology. PMID 26278892 DOI: 10.1002/cbic.201500407 |
0.483 |
|
| 2015 |
Leão PN, Nakamura H, Costa M, Pereira AR, Martins R, Vasconcelos V, Gerwick WH, Balskus EP. Biosynthesis-Assisted Structural Elucidation of the Bartolosides, Chlorinated Aromatic Glycolipids from Cyanobacteria. Angewandte Chemie (International Ed. in English). PMID 26235728 DOI: 10.1002/Anie.201503186 |
0.669 |
|
| 2015 |
Wallace S, Balskus EP. Interfacing microbial styrene production with a biocompatible cyclopropanation reaction. Angewandte Chemie (International Ed. in English). 54: 7106-9. PMID 25925138 DOI: 10.1002/Anie.201502185 |
0.528 |
|
| 2015 |
Brotherton CA, Wilson M, Byrd G, Balskus EP. Correction to Isolation of a Metabolite from the pks Island Provides Insights into Colibactin Biosynthesis and Activity. Organic Letters. 17: 2294. PMID 25893436 DOI: 10.1021/acs.orglett.5b01056 |
0.362 |
|
| 2015 |
Martínez-del Campo A, Bodea S, Hamer HA, Marks JA, Haiser HJ, Turnbaugh PJ, Balskus EP. Characterization and detection of a widely distributed gene cluster that predicts anaerobic choline utilization by human gut bacteria. Mbio. 6. PMID 25873372 DOI: 10.1128/Mbio.00042-15 |
0.635 |
|
| 2015 |
Brotherton CA, Wilson M, Byrd G, Balskus EP. Isolation of a metabolite from the pks island provides insights into colibactin biosynthesis and activity. Organic Letters. 17: 1545-8. PMID 25753745 DOI: 10.1021/acs.orglett.5b00432 |
0.425 |
|
| 2015 |
Wallace S, Schultz EE, Balskus EP. Using non-enzymatic chemistry to influence microbial metabolism. Current Opinion in Chemical Biology. 25: 71-9. PMID 25579453 DOI: 10.1016/J.Cbpa.2014.12.024 |
0.676 |
|
| 2014 |
Sirasani G, Tong L, Balskus EP. A biocompatible alkene hydrogenation merges organic synthesis with microbial metabolism. Angewandte Chemie (International Ed. in English). 53: 7785-8. PMID 24916924 DOI: 10.1002/Anie.201403148 |
0.718 |
|
| 2014 |
Wallace S, Balskus EP. Opportunities for merging chemical and biological synthesis. Current Opinion in Biotechnology. 30: 1-8. PMID 24747284 DOI: 10.1016/J.Copbio.2014.03.006 |
0.534 |
|
| 2014 |
Haiser HJ, Seim KL, Balskus EP, Turnbaugh PJ. Mechanistic insight into digoxin inactivation by Eggerthella lenta augments our understanding of its pharmacokinetics. Gut Microbes. 5: 233-8. PMID 24637603 DOI: 10.4161/Gmic.27915 |
0.688 |
|
| 2013 |
Lee Y, Umeano A, Balskus EP. Rescuing auxotrophic microorganisms with nonenzymatic chemistry. Angewandte Chemie (International Ed. in English). 52: 11800-3. PMID 24115592 DOI: 10.1002/anie.201307033 |
0.701 |
|
| 2013 |
Haiser HJ, Gootenberg DB, Chatman K, Sirasani G, Balskus EP, Turnbaugh PJ. Predicting and manipulating cardiac drug inactivation by the human gut bacterium Eggerthella lenta. Science (New York, N.Y.). 341: 295-8. PMID 23869020 DOI: 10.1126/Science.1235872 |
0.708 |
|
| 2012 |
Craciun S, Balskus EP. Microbial conversion of choline to trimethylamine requires a glycyl radical enzyme. Proceedings of the National Academy of Sciences of the United States of America. 109: 21307-12. PMID 23151509 DOI: 10.1073/pnas.1215689109 |
0.352 |
|
| 2012 |
Nakamura H, Hamer HA, Sirasani G, Balskus EP. Cylindrocyclophane biosynthesis involves functionalization of an unactivated carbon center. Journal of the American Chemical Society. 134: 18518-21. PMID 23106426 DOI: 10.1021/Ja308318P |
0.767 |
|
| 2011 |
Balskus EP, Case RJ, Walsh CT. The biosynthesis of cyanobacterial sunscreen scytonemin in intertidal microbial mat communities. Fems Microbiology Ecology. 77: 322-32. PMID 21501195 DOI: 10.1111/J.1574-6941.2011.01113.X |
0.405 |
|
| 2010 |
Balskus EP, Walsh CT. The genetic and molecular basis for sunscreen biosynthesis in cyanobacteria. Science (New York, N.Y.). 329: 1653-6. PMID 20813918 DOI: 10.1126/Science.1193637 |
0.476 |
|
| 2009 |
Balskus EP, Walsh CT. An enzymatic cyclopentyl[b]indole formation involved in scytonemin biosynthesis. Journal of the American Chemical Society. 131: 14648-9. PMID 19780555 DOI: 10.1021/Ja906752U |
0.422 |
|
| 2008 |
Balskus EP, Walsh CT. Investigating the initial steps in the biosynthesis of cyanobacterial sunscreen scytonemin. Journal of the American Chemical Society. 130: 15260-1. PMID 18954141 DOI: 10.1021/Ja807192U |
0.459 |
|
| 2008 |
Groll M, Balskus EP, Jacobsen EN. Structural analysis of spiro beta-lactone proteasome inhibitors. Journal of the American Chemical Society. 130: 14981-3. PMID 18928262 DOI: 10.1021/Ja806059T |
0.579 |
|
| 2008 |
Smith TE, Kuo WH, Balskus EP, Bock VD, Roizen JL, Theberge AB, Carroll KA, Kurihara T, Wessler JD. Total synthesis of (-)-hennoxazole A. The Journal of Organic Chemistry. 73: 142-50. PMID 18052386 DOI: 10.1021/Jo7018015 |
0.403 |
|
| 2008 |
Smith TE, Kuo W, Balskus EP, Bock VD, Roizen JL, Theberge AB, Carroll KA, Kurihara T, Wessler JD. ChemInform Abstract: Total Synthesis of (-)-Hennoxazole A (I). Cheminform. 39. DOI: 10.1002/chin.200820213 |
0.377 |
|
| 2007 |
Balskus EP, Jacobsen EN. Asymmetric catalysis of the transannular Diels-Alder reaction. Science (New York, N.Y.). 317: 1736-40. PMID 17885133 DOI: 10.1126/Science.1146939 |
0.588 |
|
| 2007 |
Smith TE, Kuo WH, Bock VD, Roizen JL, Balskus EP, Theberge AB. Total synthesis of (-)-hennoxazole A. Organic Letters. 9: 1153-5. PMID 17316014 DOI: 10.1021/Ol070244P |
0.416 |
|
| 2006 |
Balskus EP, Jacobsen EN. Alpha,beta-unsaturated beta-silyl imide substrates for catalytic, enantioselective conjugate additions: a total synthesis of (+)-lactacystin and the discovery of a new proteasome inhibitor. Journal of the American Chemical Society. 128: 6810-2. PMID 16719460 DOI: 10.1021/Ja061970A |
0.568 |
|
| 2006 |
Jacobsen E, Balskus E. Synthesis of (+)-Lactacystin Synfacts. 2006: 1202-1202. DOI: 10.1055/S-2006-955595 |
0.554 |
|
| 2004 |
Ley SV, Antonello A, Balskus EP, Booth DT, Christensen SB, Cleator E, Gold H, Högenauer K, Hünger U, Myers RM, Oliver SF, Simic O, Smith MD, Søhoel H, Woolford AJ. Synthesis of the thapsigargins. Proceedings of the National Academy of Sciences of the United States of America. 101: 12073-8. PMID 15226504 DOI: 10.1073/Pnas.0403300101 |
0.382 |
|
| 2002 |
Smith TE, Balskus EP. Synthetic studies toward hennoxazole A. Use of a selective bisoxazole alkylation as the key fragment coupling Heterocycles. 57: 1219-1225. |
0.369 |
|
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