Year |
Citation |
Score |
2019 |
McKinnell RM, Fatheree P, Choi SK, Gendron R, Jendza K, Olson Blair B, Budman J, Hill CM, Hegde LG, Yu C, McConn D, Hegde SS, Marquess DG, Klein U. Discovery of TD-0212, an Orally Active Dual Pharmacology AT Antagonist and Neprilysin Inhibitor (ARNI). Acs Medicinal Chemistry Letters. 10: 86-91. PMID 30655952 DOI: 10.1021/Acsmedchemlett.8B00462 |
0.318 |
|
2009 |
McConn DJ, Lin YS, Mathisen TL, Blough DK, Xu Y, Hashizume T, Taylor SL, Thummel KE, Shuhart MC. Reduced duodenal cytochrome P450 3A protein expression and catalytic activity in patients with cirrhosis. Clinical Pharmacology and Therapeutics. 85: 387-93. PMID 19212316 DOI: 10.1038/Clpt.2008.292 |
0.616 |
|
2008 |
Reese MJ, Wurm RM, Muir KT, Generaux GT, St John-Williams L, McConn DJ. An in vitro mechanistic study to elucidate the desipramine/bupropion clinical drug-drug interaction. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 36: 1198-201. PMID 18420781 DOI: 10.1124/dmd.107.020198 |
0.463 |
|
2004 |
Huang W, Lin YS, McConn DJ, Calamia JC, Totah RA, Isoherranen N, Glodowski M, Thummel KE. Evidence of significant contribution from CYP3A5 to hepatic drug metabolism. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 32: 1434-45. PMID 15383492 DOI: 10.1124/Dmd.104.001313 |
0.497 |
|
2004 |
McConn DJ, Lin YS, Allen K, Kunze KL, Thummel KE. Differences in the inhibition of cytochromes P450 3A4 and 3A5 by metabolite-inhibitor complex-forming drugs. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 32: 1083-91. PMID 15377640 DOI: 10.1124/Dmd.32.10.1083 |
0.614 |
|
2004 |
McConn DJ, Zhao Z. Integrating in vitro kinetic data from compounds exhibiting induction, reversible inhibition and mechanism-based inactivation: in vitro study design. Current Drug Metabolism. 5: 141-6. PMID 15078191 |
0.394 |
|
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