| Year |
Citation |
Score |
| 2024 |
Phillips KA, Kotsopoulos J, Domchek SM, Terry MB, Chamberlain JA, Bassett JK, Aeilts AM, Andrulis IL, Buys SS, Cui W, Daly MB, Eisen AF, Foulkes WD, Friedlander ML, Gronwald J, ... ... Nathanson KL, et al. Hormonal Contraception and Breast Cancer Risk for Carriers of Germline Mutations in and . Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. JCO2400176. PMID 39356978 DOI: 10.1200/JCO.24.00176 |
0.367 |
|
| 2024 |
Zanti M, O'Mahony DG, Parsons MT, Dorling L, Dennis J, Boddicker NJ, Chen W, Hu C, Naven M, Yiangou K, Ahearn TU, Ambrosone CB, Andrulis IL, Antoniou AC, Auer PL, ... ... Nathanson KL, et al. Analysis of more than 400,000 women provides case-control evidence for BRCA1 and BRCA2 variant classification. Medrxiv : the Preprint Server For Health Sciences. PMID 39281752 DOI: 10.1101/2024.09.04.24313051 |
0.309 |
|
| 2024 |
Kalia SS, Boddicker NJ, Yadav S, Huang H, Na J, Hu C, Ambrosone CB, Yao S, Haiman CA, Chen F, John EM, Kurian AW, Guo B, Lindström S, Auer P, ... ... Nathanson KL, et al. Development of a breast cancer risk prediction model integrating monogenic, polygenic, and epidemiologic risk. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. PMID 39259185 DOI: 10.1158/1055-9965.EPI-24-0594 |
0.304 |
|
| 2024 |
Safonov A, Marra A, Bandlamudi C, O'Leary B, Wubbenhorst B, Ferraro E, Moiso E, Lee M, An J, Donoghue MTA, Will M, Pareja F, Nizialek E, Lukashchuk N, Sofianopoulou E, ... ... Nathanson KL, et al. Tumor suppressor heterozygosity and homologous recombination deficiency mediate resistance to front-line therapy in breast cancer. Biorxiv : the Preprint Server For Biology. PMID 39253462 DOI: 10.1101/2024.02.05.578934 |
0.359 |
|
| 2024 |
Sun X, Verma SP, Jia G, Wang X, Ping J, Guo X, Shu XO, Chen J, Derkach A, Cai Q, Liang X, Long J, Offit K, Oh JH, Reiner AS, ... ... Nathanson KL, et al. Case-Case Genome-Wide Analyses Identify Subtype-Informative Variants that Confer Risk for Breast Cancer. Cancer Research. PMID 38832928 DOI: 10.1158/0008-5472.CAN-23-3854 |
0.377 |
|
| 2024 |
Jia G, Ping J, Guo X, Yang Y, Tao R, Li B, Ambs S, Barnard ME, Chen Y, Garcia-Closas M, Gu J, Hu JJ, Huo D, John EM, Li CI, ... ... Nathanson KL, et al. Genome-wide association analyses of breast cancer in women of African ancestry identify new susceptibility loci and improve risk prediction. Nature Genetics. PMID 38741014 DOI: 10.1038/s41588-024-01736-4 |
0.373 |
|
| 2024 |
Ping J, Jia G, Cai Q, Guo X, Tao R, Ambrosone C, Huo D, Ambs S, Barnard ME, Chen Y, Garcia-Closas M, Gu J, Hu JJ, John EM, Li CI, ... Nathanson K, et al. Using genome and transcriptome data from African-ancestry female participants to identify putative breast cancer susceptibility genes. Nature Communications. 15: 3718. PMID 38697998 DOI: 10.1038/s41467-024-47650-5 |
0.363 |
|
| 2024 |
Ochs-Balcom HM, Preus L, Du Z, Elston RC, Teerlink CC, Jia G, Guo X, Cai Q, Long J, Ping J, Li B, Stram DO, Shu XO, Sanderson M, Gao G, ... ... Nathanson KL, et al. Novel breast cancer susceptibility loci under linkage peaks identified in African ancestry consortia. Human Molecular Genetics. PMID 38263910 DOI: 10.1093/hmg/ddae002 |
0.337 |
|
| 2023 |
Symecko H, Schnoll R, Beidas RS, Bekelman JE, Blumenthal D, Bauer AM, Gabriel P, Boisseau L, Doucette A, Powers J, Cappadocia J, McKenna DB, Richardville R, Cuff L, Offer R, ... ... Nathanson KL, et al. Protocol to evaluate sequential electronic health record-based strategies to increase genetic testing for breast and ovarian cancer risk across diverse patient populations in gynecology practices. Implementation Science : Is. 18: 57. PMID 37932730 DOI: 10.1186/s13012-023-01308-w |
0.321 |
|
| 2023 |
Brown TJ, Yablonovitch A, Till JE, Yen J, Kiedrowski LA, Hood R, O'Hara MH, Teitelbaum U, Karasic TB, Schneider C, Carpenter EL, Nathanson K, Domchek SM, Reiss KA. The Clinical Implications of Reversions in Patients with Advanced Pancreatic Cancer and Pathogenic Variants in BRCA1, BRCA2, or PALB2 After Progression on Rucaparib. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 37486343 DOI: 10.1158/1078-0432.CCR-23-1467 |
0.304 |
|
| 2023 |
Stolarova L, Kleiblova P, Zemankova P, Stastna B, Janatova M, Soukupova J, Achatz MI, Ambrosone C, Apostolou P, Arun BK, Auer P, Barnard M, Bertelsen B, Blok MJ, Boddicker N, ... ... Nathanson K, et al. ENIGMA CHEK2gether Project: A Comprehensive Study Identifies Functionally Impaired CHEK2 Germline Missense Variants Associated with Increased Breast Cancer Risk. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. OF1-OF14. PMID 37449874 DOI: 10.1158/1078-0432.CCR-23-0212 |
0.371 |
|
| 2023 |
Yoon JY, Roth JJ, Rushton CA, Morrissette JJD, Nathanson KL, Cohen RB, Rosenbaum JN. Homologous recombination pathway gene variants identified by tumor-only sequencing assays in lung carcinoma patients. Translational Lung Cancer Research. 12: 1236-1244. PMID 37425424 DOI: 10.21037/tlcr-22-749 |
0.331 |
|
| 2023 |
Hu C, Belur Nagaraj A, Shimelis H, Montalban G, Lee KY, Huang H, Lumby CA, Na J, Susswein LR, Roberts ME, Marshall ML, Hiraki S, LaDuca H, Chao E, Yussuf A, ... ... Nathanson KL, et al. Functional and clinical characterization of variants of uncertain significance identifies a hotspot for inactivating missense variants in RAD51C. Cancer Research. PMID 37253112 DOI: 10.1158/0008-5472.CAN-22-2319 |
0.366 |
|
| 2023 |
Lau-Min KS, McCarthy AM, Nathanson KL, Domchek SM. Nationwide Trends and Determinants of Germline BRCA1/2 Testing in Patients With Breast and Ovarian Cancer. Journal of the National Comprehensive Cancer Network : Jnccn. 21: 351-358.e4. PMID 37015340 DOI: 10.6004/jnccn.2022.7257 |
0.328 |
|
| 2023 |
Yadav S, Boddicker NJ, Na J, Polley EC, Hu C, Hart SN, Gnanaolivu RD, Larson N, Holtegaard S, Huang H, Dunn CA, Teras LR, Patel AV, Lacey JV, Neuhausen SL, ... ... Nathanson KL, et al. Contralateral Breast Cancer Risk Among Carriers of Germline Pathogenic Variants in , , , , and . Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. JCO2201239. PMID 36623243 DOI: 10.1200/JCO.22.01239 |
0.331 |
|
| 2022 |
Shah JB, Pueschl D, Wubbenhorst B, Fan M, Pluta J, D'Andrea K, Hubert AP, Shilan JS, Zhou W, Kraya AA, Llop Guevara A, Ruan C, Serra V, Balmaña J, Feldman M, ... ... Nathanson KL, et al. Analysis of matched primary and recurrent BRCA1/2 mutation-associated tumors identifies recurrence-specific drivers. Nature Communications. 13: 6728. PMID 36344544 DOI: 10.1038/s41467-022-34523-y |
0.371 |
|
| 2022 |
Hakkaart C, Pearson JF, Marquart L, Dennis J, Wiggins GAR, Barnes DR, Robinson BA, Mace PD, Aittomäki K, Andrulis IL, Arun BK, Azzollini J, Balmaña J, Barkardottir RB, Belhadj S, ... ... Nathanson KL, et al. Copy number variants as modifiers of breast cancer risk for BRCA1/BRCA2 pathogenic variant carriers. Communications Biology. 5: 1061. PMID 36203093 DOI: 10.1038/s42003-022-03978-6 |
0.386 |
|
| 2022 |
Gray GK, Li CM, Rosenbluth JM, Selfors LM, Girnius N, Lin JR, Schackmann RCJ, Goh WL, Moore K, Shapiro HK, Mei S, D'Andrea K, Nathanson KL, Sorger PK, Santagata S, et al. A human breast atlas integrating single-cell proteomics and transcriptomics. Developmental Cell. PMID 35617956 DOI: 10.1016/j.devcel.2022.05.003 |
0.31 |
|
| 2021 |
Yadav S, Hu C, Nathanson KL, Weitzel JN, Goldgar DE, Kraft P, Gnanaolivu RD, Na J, Huang H, Boddicker NJ, Larson N, Gao C, Yao S, Weinberg C, Vachon CM, et al. Germline Pathogenic Variants in Cancer Predisposition Genes Among Women With Invasive Lobular Carcinoma of the Breast. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. JCO2100640. PMID 34672684 DOI: 10.1200/JCO.21.00640 |
0.317 |
|
| 2021 |
Barnes DR, Silvestri V, Leslie G, McGuffog L, Dennis J, Yang X, Adlard J, Agnarsson BA, Ahmed M, Aittomäki K, Andrulis IL, Arason A, Arnold N, Auber B, Azzollini J, ... ... Nathanson KL, et al. Breast and Prostate Cancer Risks for Male BRCA1 and BRCA2 Pathogenic Variant Carriers Using Polygenic Risk Scores. Journal of the National Cancer Institute. PMID 34320204 DOI: 10.1093/jnci/djab147 |
0.3 |
|
| 2021 |
Boddicker NJ, Hu C, Weitzel JN, Kraft P, Nathanson KL, Goldgar DE, Na J, Huang H, Gnanaolivu RD, Larson N, Yussuf A, Yao S, Vachon CM, Trentham-Dietz A, Teras L, et al. Risk of Late-Onset Breast Cancer in Genetically Predisposed Women. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. JCO2100531. PMID 34292776 DOI: 10.1200/JCO.21.00531 |
0.308 |
|
| 2021 |
Adedokun B, Du Z, Gao G, Ahearn TU, Lunetta KL, Zirpoli G, Figueroa J, John EM, Bernstein L, Zheng W, Hu JJ, Ziegler RG, Nyante S, Bandera EV, Ingles SA, ... ... Nathanson KL, et al. Cross-ancestry GWAS meta-analysis identifies six breast cancer loci in African and European ancestry women. Nature Communications. 12: 4198. PMID 34234117 DOI: 10.1038/s41467-021-24327-x |
0.371 |
|
| 2021 |
Lakeman IMM, van den Broek AJ, Vos JAM, Barnes DR, Adlard J, Andrulis IL, Arason A, Arnold N, Arun BK, Balmaña J, Barrowdale D, Benitez J, Borg A, Caldés T, Caligo MA, ... ... Nathanson KL, et al. The predictive ability of the 313 variant-based polygenic risk score for contralateral breast cancer risk prediction in women of European ancestry with a heterozygous BRCA1 or BRCA2 pathogenic variant. Genetics in Medicine : Official Journal of the American College of Medical Genetics. PMID 34113011 DOI: 10.1038/s41436-021-01198-7 |
0.343 |
|
| 2021 |
Gao C, Polley EC, Hart SN, Huang H, Hu C, Gnanaolivu R, Lilyquist J, Boddicker NJ, Na J, Ambrosone CB, Auer PL, Bernstein L, Burnside ES, Eliassen AH, Gaudet MM, ... ... Nathanson KL, et al. Risk of Breast Cancer Among Carriers of Pathogenic Variants in Breast Cancer Predisposition Genes Varies by Polygenic Risk Score. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. JCO2001992. PMID 34101481 DOI: 10.1200/JCO.20.01992 |
0.348 |
|
| 2021 |
Coignard J, Lush M, Beesley J, O'Mara TA, Dennis J, Tyrer JP, Barnes DR, McGuffog L, Leslie G, Bolla MK, Adank MA, Agata S, Ahearn T, Aittomäki K, Andrulis IL, ... ... Nathanson KL, et al. Author Correction: A case-only study to identify genetic modifiers of breast cancer risk for BRCA1/BRCA2 mutation carriers. Nature Communications. 12: 2986. PMID 33990587 DOI: 10.1038/s41467-021-23162-4 |
0.36 |
|
| 2021 |
Coignard J, Lush M, Beesley J, O'Mara TA, Dennis J, Tyrer JP, Barnes DR, McGuffog L, Leslie G, Bolla MK, Adank MA, Agata S, Ahearn T, Aittomäki K, Andrulis IL, ... ... Nathanson KL, et al. A case-only study to identify genetic modifiers of breast cancer risk for BRCA1/BRCA2 mutation carriers. Nature Communications. 12: 1078. PMID 33597508 DOI: 10.1038/s41467-020-20496-3 |
0.386 |
|
| 2021 |
Hu C, Hart SN, Gnanaolivu R, Huang H, Lee KY, Na J, Gao C, Lilyquist J, Yadav S, Boddicker NJ, Samara R, Klebba J, Ambrosone CB, Anton-Culver H, Auer P, ... ... Nathanson KL, et al. A Population-Based Study of Genes Previously Implicated in Breast Cancer. The New England Journal of Medicine. PMID 33471974 DOI: 10.1056/NEJMoa2005936 |
0.348 |
|
| 2020 |
Muranen TA, Khan S, Fagerholm R, Aittomäki K, Cunningham JM, Dennis J, Leslie G, McGuffog L, Parsons MT, Simard J, Slager S, Soucy P, Easton DF, Tischkowitz M, Spurdle AB, ... ... Nathanson KL, et al. Association of germline variation with the survival of women with pathogenic variants and breast cancer. Npj Breast Cancer. 6: 44. PMID 32964118 DOI: 10.1038/s41523-020-00185-6 |
0.358 |
|
| 2020 |
Maxwell KN, Wenz BM, Kulkarni A, Wubbenhorst B, D'Andrea K, Weathers B, Goodman N, Vijai J, Lilyquist J, Hart SN, Slavin TP, Schrader KA, Ravichandran V, Thomas T, Hu C, ... ... Nathanson KL, et al. Mutation Rates in Cancer Susceptibility Genes in Patients With Breast Cancer With Multiple Primary Cancers. Jco Precision Oncology. 4. PMID 32954205 DOI: 10.1200/PO.19.00301 |
0.376 |
|
| 2020 |
Powers J, Pinto EM, Barnoud T, Leung JC, Martynyuk T, Kossenkov AV, Phillips AH, Desai H, Hausler R, Kelly G, Le AN, Li MM, MacFarland SP, Pyle LC, Zelley K, ... Nathanson KL, et al. A rare TP53 mutation predominant in Ashkenazi Jews confers risk of multiple cancers. Cancer Research. PMID 32675277 DOI: 10.1158/0008-5472.Can-20-1390 |
0.409 |
|
| 2020 |
Barnes DR, Rookus MA, McGuffog L, Leslie G, Mooij TM, Dennis J, Mavaddat N, Adlard J, Ahmed M, Aittomäki K, Andrieu N, Andrulis IL, Arnold N, Arun BK, Azzollini J, ... ... Nathanson KL, et al. Polygenic risk scores and breast and epithelial ovarian cancer risks for carriers of BRCA1 and BRCA2 pathogenic variants. Genetics in Medicine : Official Journal of the American College of Medical Genetics. PMID 32665703 DOI: 10.1038/S41436-020-0862-X |
0.452 |
|
| 2020 |
Zhang YD, Hurson AN, Zhang H, Choudhury PP, Easton DF, Milne RL, Simard J, Hall P, Michailidou K, Dennis J, Schmidt MK, Chang-Claude J, Gharahkhani P, Whiteman D, Campbell PT, ... ... Nathanson KL, et al. Assessment of polygenic architecture and risk prediction based on common variants across fourteen cancers. Nature Communications. 11: 3353. PMID 32620889 DOI: 10.1038/S41467-020-16483-3 |
0.429 |
|
| 2020 |
Silvestri V, Leslie G, Barnes DR, Agnarsson BA, Aittomäki K, Alducci E, Andrulis IL, Barkardottir RB, Barroso A, Barrowdale D, Benitez J, Bonanni B, Borg A, Buys SS, ... ... Nathanson KL, et al. Characterization of the Cancer Spectrum in Men With Germline BRCA1 and BRCA2 Pathogenic Variants: Results From the Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA). Jama Oncology. PMID 32614418 DOI: 10.1001/Jamaoncol.2020.2134 |
0.453 |
|
| 2020 |
Palmer JR, Polley EC, Hu C, John EM, Haiman C, Hart SN, Gaudet M, Pal T, Anton-Culver H, Trentham-Dietz A, Bernstein L, Ambrosone CB, Bandera EV, Bertrand KA, Bethea TN, ... ... Nathanson KL, et al. Contribution of Germline Predisposition Gene Mutations to Breast Cancer Risk in African American Women. Journal of the National Cancer Institute. PMID 32427313 DOI: 10.1093/Jnci/Djaa040 |
0.48 |
|
| 2020 |
Zhang H, Ahearn TU, Lecarpentier J, Barnes D, Beesley J, Qi G, Jiang X, O'Mara TA, Zhao N, Bolla MK, Dunning AM, Dennis J, Wang Q, Ful ZA, Aittomäki K, ... ... Nathanson KL, et al. Genome-wide association study identifies 32 novel breast cancer susceptibility loci from overall and subtype-specific analyses. Nature Genetics. PMID 32424353 DOI: 10.1038/s41588-020-0609-2 |
0.401 |
|
| 2020 |
Stjepanovic N, Villacampa G, Nead KT, Torres-Esquius S, Melis GG, Nathanson KL, Teule A, Brunet J, Y Cajal TR, Llort G, Dienstmann R, Rue M, Domchek SM, Balmaña J. Association of premenopausal risk-reducing salpingo-oophorectomy with breast cancer risk in BRCA1/2 mutation carriers: Maximising bias-reduction. European Journal of Cancer (Oxford, England : 1990). 132: 53-60. PMID 32325420 DOI: 10.1016/J.Ejca.2020.03.009 |
0.443 |
|
| 2020 |
Li MM, Chao E, Esplin ED, Miller DT, Nathanson KL, Plon SE, Scheuner MT, Stewart DR. Points to consider for reporting of germline variation in patients undergoing tumor testing: a statement of the American College of Medical Genetics and Genomics (ACMG). Genetics in Medicine : Official Journal of the American College of Medical Genetics. PMID 32321997 DOI: 10.1038/S41436-020-0783-8 |
0.301 |
|
| 2020 |
Le AN, Harton J, Desai H, Powers J, Zelley K, Bradbury AR, Nathanson KL, Shah PD, Doucette A, Freedman GM, Gabriel P, Domchek SM, MacFarland SP, Maxwell KN. Frequency of radiation-induced malignancies post-adjuvant radiotherapy for breast cancer in patients with Li-Fraumeni syndrome. Breast Cancer Research and Treatment. PMID 32246378 DOI: 10.1007/S10549-020-05612-7 |
0.446 |
|
| 2020 |
Feng H, Gusev A, Pasaniuc B, Wu L, Long J, Abu-Full Z, Aittomäki K, Andrulis IL, Anton-Culver H, Antoniou AC, Arason A, Arndt V, Aronson KJ, Arun BK, Asseryanis E, ... ... Nathanson KL, et al. Transcriptome-wide association study of breast cancer risk by estrogen-receptor status. Genetic Epidemiology. PMID 32115800 DOI: 10.1002/gepi.22288 |
0.352 |
|
| 2020 |
Fachal L, Aschard H, Beesley J, Barnes DR, Allen J, Kar S, Pooley KA, Dennis J, Michailidou K, Turman C, Soucy P, Lemaçon A, Lush M, Tyrer JP, Ghoussaini M, ... ... Nathanson KL, et al. Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes. Nature Genetics. PMID 31911677 DOI: 10.1038/s41588-019-0537-1 |
0.313 |
|
| 2020 |
Daneshvar M, Mendhiratta N, Srinivasan R, Jonasch E, Ball MW, Metwali AR, Brugarolas J, Singer EA, Nathanson K, Pierorazio PM, Boris RS, Finelli A, Pal SK, Hakimi AA, Kutikov A, et al. Genetic risk assessment for hereditary RCC: Report from the consensus panel meeting. Journal of Clinical Oncology. 38: 615-615. DOI: 10.1200/Jco.2020.38.6_Suppl.615 |
0.391 |
|
| 2020 |
Morgan K, Symecko H, Kamara D, Jenkins C, Levin J, Lester J, Spielman K, Pace LE, Marcell V, Wildman T, Fesko YA, Heitler J, Robson ME, Nathanson K, Tung NM, et al. The BRCA founder outreach study: Initial results of a digital health model. Journal of Clinical Oncology. 38: 2007-2007. DOI: 10.1200/Jco.2020.38.15_Suppl.2007 |
0.373 |
|
| 2020 |
Greenberg S, Jacobs M, Wachtel H, Anson A, Buchmann L, Cohen D, Bonnani M, Bennett B, Naumer A, Schaefer A, Kohlmann W, Nathanson K, Else T, Fishbein L. Tumor detection rates in screening carriers with SDHx-related hereditary paraganglioma-pheochromocytoma syndrome based on prior tumor history. Journal of Clinical Oncology. 38: 1545-1545. DOI: 10.1200/Jco.2020.38.15_Suppl.1545 |
0.353 |
|
| 2020 |
Gao C, Polley EC, Hu C, Hart SN, Gnanaolivu R, Lee KY, Na J, Boddicker NJ, Samara R, Auer P, Bernstein L, Gaudet M, Trentham-Dietz A, Yao S, Haiman C, ... ... Nathanson KL, et al. Abstract PD3-02: Polygenic risk scores provide clinically meaningful risk stratification among women carrying moderate penetrance pathogenic variants in breast cancer predisposition genes: Results from the CARRIERS study Cancer Research. 80. DOI: 10.1158/1538-7445.Sabcs19-Pd3-02 |
0.483 |
|
| 2020 |
Couch FJ, Hu C, Hart SN, Gnanaolivu R, Lee KY, Na J, Gao C, Boddicker NJ, Eckloff B, Samara R, Klebba J, Ambrosone CB, Anton-Culver H, Auer P, Bernstein L, ... ... Nathanson KL, et al. Abstract PD3-01: Population-based breast cancer risk estimates for predisposition gene mutations: Results from the CARRIERS study Cancer Research. 80. DOI: 10.1158/1538-7445.Sabcs19-Pd3-01 |
0.507 |
|
| 2020 |
Le AN, Powers J, Zelley K, Bradbury A, Shah P, Freedman G, Nathanson K, Domchek SM, MacFarland SP, Maxwell KN. Abstract P4-12-33: Frequency of radiation-induced malignancies post-adjuvant radiotherapy for breast cancer in patients with Li-Fraumeni syndrome Cancer Research. DOI: 10.1158/1538-7445.Sabcs19-P4-12-33 |
0.376 |
|
| 2020 |
Adedokun B, Du Z, Gao G, Ahearn T, Lunetta KL, Zirpoli G, Figueroa J, John EM, Bernstein L, Zheng W, Hu JJ, Ziegler RG, Nyante S, Bandera EV, Ingles SA, ... ... Nathanson KL, et al. Abstract 4613: Cross-ancestry genome-wide association study identifies six new loci for breast cancer in women of African and european ancestry Epidemiology. DOI: 10.1158/1538-7445.Am2020-4613 |
0.401 |
|
| 2020 |
Shah JB, Wubbenhorst B, Pluta J, Feltcher C, Schmucker L, D'Andrea K, Symecko H, Ruan C, Nayak A, Maxwell KN, Domchek S, Nathanson KL. Abstract 2500: Copy number variation in recurrent BRCA1/2 germline mutation-associated breast and ovarian cancers Cancer Research. 80: 2500-2500. DOI: 10.1158/1538-7445.Am2020-2500 |
0.5 |
|
| 2020 |
Du Z, Gao G, Adedokun B, Ahearn T, Lunetta KL, Zirpoli G, Troester M, Ruiz-Narváez EA, Haddad S, Figueroa J, John EM, Bernstein L, Zheng W, Hu JJ, Ziegler RG, ... ... Nathanson KL, et al. Abstract 2320: Evaluating a polygenic risk score for breast cancer in women of African ancestry Epidemiology. 80: 2320-2320. DOI: 10.1158/1538-7445.Am2020-2320 |
0.441 |
|
| 2020 |
Pluta J, Pyle L, Bishop T, Benitez J, Cortessis V, Ferlin A, Gietema J, Greene M, Grotmol T, Gupta R, Hamilton R, Hildebrandt M, Kiemeney L, Lessel D, Rafnar T, ... ... Nathanson K, et al. Abstract 1203: Identification of 22 novel loci associated with susceptibility to testicular germ cell tumors Epidemiology. DOI: 10.1158/1538-7445.Am2020-1203 |
0.332 |
|
| 2020 |
Mezina AI, Philips N, Bogus Z, Erez N, Nathanson KL, Hoteit M, Wangensteen KJ. Mo1404 PREVALENCE OF PATHOGENIC GERMLINE VARIANTS IN CANCER-RISK GENES IN HEPATOCELLULAR CARCINOMA Gastroenterology. 158: S-1396. DOI: 10.1016/S0016-5085(20)34158-5 |
0.371 |
|
| 2019 |
Yang X, Leslie G, Doroszuk A, Schneider S, Allen J, Decker B, Dunning AM, Redman J, Scarth J, Plaskocinska I, Luccarini C, Shah M, Pooley K, Dorling L, Lee A, ... ... Nathanson KL, et al. Cancer Risks Associated With Germline Pathogenic Variants: An International Study of 524 Families. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. JCO1901907. PMID 31841383 DOI: 10.1200/Jco.19.01907 |
0.441 |
|
| 2019 |
Wattenberg MM, Asch D, Yu S, O'Dwyer PJ, Domchek SM, Nathanson KL, Rosen MA, Beatty GL, Siegelman ES, Reiss KA. Platinum response characteristics of patients with pancreatic ductal adenocarcinoma and a germline BRCA1, BRCA2 or PALB2 mutation. British Journal of Cancer. PMID 31787751 DOI: 10.1038/S41416-019-0582-7 |
0.387 |
|
| 2019 |
Patel VL, Busch EL, Friebel TM, Cronin A, Leslie G, McGuffog L, Adlard J, Agata S, Agnarsson BA, Ahmed M, Aittomäki K, Alducci E, Andrulis IL, Arason A, Arnold N, ... ... Nathanson KL, et al. Association of Genomic Domains in BRCA1 and BRCA2 with Prostate Cancer Risk and Aggressiveness. Cancer Research. PMID 31723001 DOI: 10.1158/0008-5472.Can-19-1840 |
0.385 |
|
| 2019 |
Ostrowski PJ, Zachariou A, Loveday C, Beleza-Meireles A, Bertoli M, Dean J, Douglas AGL, Ellis I, Foster A, Graham JM, Hague J, Hilhorst-Hofstee Y, Hoffer M, Johnson D, Josifova D, ... ... Nathanson K, et al. The CHD8 overgrowth syndrome: A detailed evaluation of an emerging overgrowth phenotype in 27 patients. American Journal of Medical Genetics. Part C, Seminars in Medical Genetics. PMID 31721432 DOI: 10.1002/Ajmg.C.31749 |
0.305 |
|
| 2019 |
Figlioli G, Bogliolo M, Catucci I, Caleca L, Lasheras SV, Pujol R, Kiiski JI, Muranen TA, Barnes DR, Dennis J, Michailidou K, Bolla MK, Leslie G, Aalfs CM, ... ... Nathanson KL, et al. The :p.Arg658* truncating variant is associated with risk of triple-negative breast cancer. Npj Breast Cancer. 5: 38. PMID 31700994 DOI: 10.1038/s41523-019-0127-5 |
0.382 |
|
| 2019 |
Jiang X, Finucane HK, Schumacher FR, Schmit SL, Tyrer JP, Han Y, Michailidou K, Lesseur C, Kuchenbaecker KB, Dennis J, Conti DV, Casey G, Gaudet MM, Huyghe JR, Albanes D, ... ... Nathanson KL, et al. Publisher Correction: Shared heritability and functional enrichment across six solid cancers. Nature Communications. 10: 4386. PMID 31548585 DOI: 10.1038/S41467-019-12095-8 |
0.315 |
|
| 2019 |
Benci JL, Johnson LR, Choa R, Xu Y, Qiu J, Zhou Z, Xu B, Ye D, Nathanson KL, June CH, Wherry EJ, Zhang NR, Ishwaran H, Hellmann MD, Wolchok JD, et al. Opposing Functions of Interferon Coordinate Adaptive and Innate Immune Responses to Cancer Immune Checkpoint Blockade. Cell. 178: 933-948.e14. PMID 31398344 DOI: 10.1016/J.Cell.2019.07.019 |
0.32 |
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| 2019 |
Hammet F, Mahmood K, Green TR, Nguyen-Dumont T, Southey MC, Buchanan DD, Lonie A, Nathanson KL, Couch FJ, Pope BJ, Park DJ. Hi-Plex2: a simple and robust approach to targeted sequencing-based genetic screening. Biotechniques. PMID 31267764 DOI: 10.2144/Btn-2019-0026 |
0.327 |
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| 2019 |
Qian F, Rookus MA, Leslie G, Risch HA, Greene MH, Aalfs CM, Adank MA, Adlard J, Agnarsson BA, Ahmed M, Aittomäki K, Andrulis IL, Arnold N, Arun BK, Ausems MGEM, ... ... Nathanson KL, et al. Mendelian randomisation study of height and body mass index as modifiers of ovarian cancer risk in 22,588 BRCA1 and BRCA2 mutation carriers. British Journal of Cancer. PMID 31213659 DOI: 10.1038/S41416-019-0492-8 |
0.409 |
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| 2019 |
Parsons MT, Tudini E, Li H, Hahnen E, Wappenschmidt B, Feliubadaló L, Aalfs CM, Agata S, Aittomäki K, Alducci E, Alonso-Cerezo MC, Arnold N, Auber B, Austin R, Azzollini J, ... ... Nathanson KL, et al. Large scale multifactorial likelihood quantitative analysis of BRCA1 and BRCA2 variants: An ENIGMA resource to support clinical variant classification. Human Mutation. PMID 31131967 DOI: 10.1002/Humu.23818 |
0.413 |
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| 2019 |
Friebel TM, Andrulis IL, Balmaña J, Blanco AM, Couch FJ, Daly MB, Domchek SM, Easton DF, Foulkes WD, Ganz PA, Garber J, Glendon G, Greene MH, Hulick PJ, Isaacs C, ... ... Nathanson KL, et al. BRCA1 and BRCA2 Pathogenic Sequence Variants in Women of African Origin or Ancestry. Human Mutation. PMID 31112363 DOI: 10.1002/Humu.23804 |
0.383 |
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| 2019 |
Ferreira MA, Gamazon ER, Al-Ejeh F, Aittomäki K, Andrulis IL, Anton-Culver H, Arason A, Arndt V, Aronson KJ, Arun BK, Asseryanis E, Azzollini J, Balmaña J, Barnes DR, Barrowdale D, ... ... Nathanson KL, et al. Genome-wide association and transcriptome studies identify target genes and risk loci for breast cancer. Nature Communications. 10: 1741. PMID 30988301 DOI: 10.1038/s41467-018-08053-5 |
0.36 |
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| 2019 |
Kraya AA, Maxwell KN, Wubbenhorst B, Wenz BM, Pluta J, Rech AJ, Dorfman LM, Lunceford N, Barrett A, Mitra N, Morrissette JJ, Feldman M, Nayak A, Domchek SM, Vonderheide RH, ... Nathanson KL, et al. Genomic signatures predict the immunogenicity of BRCA-deficient breast cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 30914433 DOI: 10.1158/1078-0432.Ccr-18-0468 |
0.443 |
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| 2019 |
Jiang X, Finucane HK, Schumacher FR, Schmit SL, Tyrer JP, Han Y, Michailidou K, Lesseur C, Kuchenbaecker KB, Dennis J, Conti DV, Casey G, Gaudet MM, Huyghe JR, Albanes D, ... ... Nathanson KL, et al. Shared heritability and functional enrichment across six solid cancers. Nature Communications. 10: 431. PMID 30683880 DOI: 10.1038/S41467-018-08054-4 |
0.428 |
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| 2019 |
AlDubayan SH, Pyle LC, Gamulin M, Kulis T, Moore ND, Taylor-Weiner A, Hamid AA, Reardon B, Wubbenhorst B, Godse R, Vaughn DJ, Jacobs LA, Meien S, Grgic M, Kastelan Z, ... ... Nathanson KL, et al. Association of Inherited Pathogenic Variants in Checkpoint Kinase 2 (CHEK2) With Susceptibility to Testicular Germ Cell Tumors. Jama Oncology. PMID 30676620 DOI: 10.1001/Jamaoncol.2018.6477 |
0.368 |
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| 2019 |
Shah PD, Symecko H, Batson M, Pundock S, Rustgi N, Haggerty AF, Ko EM, Martin LP, Nathanson K, Domchek SM. EMR documentation of genetics evaluations in patients with ovarian cancer. Journal of Clinical Oncology. 37: e13156-e13156. DOI: 10.1200/Jco.2019.37.15_Suppl.E13156 |
0.374 |
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| 2019 |
Morgan K, Gabriel C, Symecko H, Lester J, Levin J, Kamara D, Spielman K, Jenkins C, Hamilton JG, Fesko YA, Heitler J, Block J, Pace L, Robson ME, Nathanson K, et al. Early results from the BRCA Founder Outreach (BFOR) Study: Population genetic screening using a medical model. Journal of Clinical Oncology. 37: 1578-1578. DOI: 10.1200/Jco.2019.37.15_Suppl.1578 |
0.315 |
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| 2019 |
Palmer JR, Hu C, Hart S, Gnanaolivu RD, Gao C, Anton-Culver H, Trentham-Dietz A, Bernstein L, Weitzel JN, Domchek SM, Goldgar D, Nathanson K, Pal T, John EM, Gaudet M, et al. Genetic predisposition to breast cancer among African American women. Journal of Clinical Oncology. 37: 104-104. DOI: 10.1200/Jco.2019.37.15_Suppl.104 |
0.506 |
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| 2019 |
Stjepanovic N, Villacampa G, Nead K, Torres S, Gomez L, Nathanson K, Teule A, Brunet J, Cajal TRy, Llort G, Dienstmann R, Rue M, Domchek S, Balmana J. Abstract P5-09-04: Impact of premenopausal RRSO on breast cancer risk in BRCA1/2 mutation carriers: Maximizing bias-reduction Cancer Research. 79. DOI: 10.1158/1538-7445.Sabcs18-P5-09-04 |
0.451 |
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| 2019 |
Couch F, Hu C, Hart S, Gnanaolivu R, Lilyquist J, Lee K, Gao C, Eckloff B, Samara R, Klebba J, Auer P, Bernstein L, Gaudet M, Haiman C, Palmer J, ... ... Nathanson K, et al. Abstract GS2-01: Age-related breast cancer risk estimates for the general population based on sequencing of cancer predisposition genes in 19,228 breast cancer patients and 20,211 matched unaffected controls from US based cohorts in the CARRIERS study Cancer Research. 79. DOI: 10.1158/1538-7445.Sabcs18-Gs2-01 |
0.503 |
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| 2019 |
Gao C, Hu C, Hart SN, Gnanaolivu R, Lee KY, Lilyquist J, Boddicker NJ, Eckloff B, Samara R, Klebba J, Auer P, Bernstein L, Gaudet M, Anton-Culver H, Trentham-Dietz A, ... ... Nathanson KL, et al. Abstract 4177: The joint effects of polygenic risk scores and pathogenic variants in cancer predisposition genes on breast cancer risk in the general population: results from the CARRIERS study Epidemiology. DOI: 10.1158/1538-7445.Sabcs18-4177 |
0.442 |
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| 2019 |
Couch FJ, Hu C, Hart SN, Gnanaolivu R, Lilyquist J, Lee KY, Gao C, Eckloff B, Anton-Culver H, Auer P, Bernstein L, Gaudet M, Haiman C, Palmer J, Tentham-Dietz A, ... ... Nathanson KL, et al. Abstract 4169: Population-based breast cancer risk estimates associated with cancer predisposition gene mutations from 32,298 breast cancer patients and 31,869 matched unaffected controls from the CARRIERS study Epidemiology. DOI: 10.1158/1538-7445.Sabcs18-4169 |
0.481 |
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| 2019 |
Kiernan E, Bastian P, Dorfman L, Anastopoulos IN, Wubbenhorst B, Krepler C, Rebecca V, Herlyn M, Nathanson K. Abstract 1682: Non-V600 BRAF mutants in melanoma: Multiple MAPK mutations and distinctive RNA expression Cancer Research. DOI: 10.1158/1538-7445.Sabcs18-1682 |
0.302 |
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| 2019 |
Binder KAR, Mick R, O'Hara M, Teitelbaum U, Karasic T, Schneider C, O'Dwyer PJ, Carpenter E, Pantel A, Makvandi M, Mankoff D, Nathanson K, Maxwell K, Cowden S, Fuhrer MJ, et al. Abstract CT234: A Phase II, single arm study of maintenance rucaparib in patients with platinum-sensitive advanced pancreatic cancer and a pathogenic germline or somatic mutation inBRCA1, BRCA2orPALB2 Cancer Research. 79. DOI: 10.1158/1538-7445.Am2019-Ct234 |
0.394 |
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| 2019 |
Pyle LC, Pluta J, Nead KT, Mitra N, Benitez J, Bishop DT, Cortessis V, Ferlin A, Gietema J, Greene M, Grotmol T, Gupta R, Hamilton R, Hildebrandt MA, Haugen TB, ... ... Nathanson KL, et al. Abstract 2684: Identification of 14 novel genetic loci for testicular germ cell tumor susceptibility Cancer Research. 79: 2684-2684. DOI: 10.1158/1538-7445.Am2019-2684 |
0.416 |
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| 2018 |
Parekh V, Sobanko J, Miller CJ, Karakousis G, Xu W, Letrero R, Elenitsas R, Xu X, Elder DE, Amaravadi R, Schuchter LM, Nathanson KL, Wilson MA, Chu EY. NRAS Q61R and BRAF G466A Mutations in Atypical Melanocytic Lesions Newly Arising in Advanced Melanoma Patients Treated with Vemurafenib. Journal of Cutaneous Pathology. PMID 30552700 DOI: 10.1111/Cup.13401 |
0.342 |
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| 2018 |
Qian F, Wang S, Mitchell J, McGuffog L, Barrowdale D, Leslie G, Oosterwijk JC, Chung WK, Evans DG, Engel C, Kast K, Aalfs CM, Adank MA, Adlard J, Agnarsson BA, ... ... Nathanson KL, et al. Height and Body Mass Index as Modifiers of Breast Cancer Risk in BRCA1/2 Mutation Carriers: A Mendelian Randomization Study. Journal of the National Cancer Institute. PMID 30312457 DOI: 10.1093/jnci/djy132 |
0.347 |
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| 2018 |
MacFarland SP, Zelley K, Long JM, McKenna D, Mamula P, Domchek SM, Nathanson KL, Brodeur GM, Rustgi AK, Katona BW, Maxwell KN. Earlier colorectal cancer screening may be necessary in patients with Li-Fraumeni Syndrome. Gastroenterology. PMID 30243621 DOI: 10.1053/J.Gastro.2018.09.036 |
0.318 |
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| 2018 |
Walker LC, Marquart L, Pearson JF, Wiggins GAR, O'Mara TA, Parsons MT, Barrowdale D, McGuffog L, Dennis J, Benitez J, Slavin TP, Radice P, Frost D, ... ... Nathanson KL, et al. Correction: Evaluation of copy-number variants as modifiers of breast and ovarian cancer risk for BRCA1 pathogenic variant carriers. European Journal of Human Genetics : Ejhg. PMID 30135485 DOI: 10.1038/s41431-018-0216-1 |
0.316 |
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| 2018 |
Shen H, Shih J, Hollern DP, Wang L, Bowlby R, Tickoo SK, Thorsson V, Mungall AJ, Newton Y, Hegde AM, Armenia J, Sánchez-Vega F, Pluta J, Pyle LC, Mehra R, ... ... Nathanson KL, et al. Integrated Molecular Characterization of Testicular Germ Cell Tumors. Cell Reports. 23: 3392-3406. PMID 29898407 DOI: 10.1016/J.Celrep.2018.05.039 |
0.388 |
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| 2018 |
Wang S, Huo D, Ogundiran TO, Ojengbede O, Zheng W, Nathanson KL, Nemesure B, Ambs S, Olopade OI, Zheng Y. Genetic variation in the Hippo pathway and breast cancer risk in women of African ancestry. Molecular Carcinogenesis. PMID 29873413 DOI: 10.1002/Mc.22845 |
0.468 |
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| 2018 |
Powis Z, Espenschied CR, LaDuca H, Hagman KD, Paudyal T, Li S, Inaba H, Mauer A, Nathanson KL, Knost J, Chao EC, Tang S. Clinical germline diagnostic exome sequencing for hereditary cancer: Findings within novel candidate genes are prevalent. Cancer Genetics. 224: 12-20. PMID 29778231 DOI: 10.1016/J.Cancergen.2018.04.002 |
0.407 |
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| 2018 |
Ochocki JD, Khare S, Hess M, Ackerman D, Qiu B, Daisak JI, Worth AJ, Lin N, Lee P, Xie H, Li B, Wubbenhorst B, Maguire TG, Nathanson KL, Alwine JC, et al. Arginase 2 Suppresses Renal Carcinoma Progression via Biosynthetic Cofactor Pyridoxal Phosphate Depletion and Increased Polyamine Toxicity. Cell Metabolism. PMID 29754953 DOI: 10.1016/J.Cmet.2018.04.009 |
0.333 |
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| 2018 |
Wang Y, Gray DR, Robbins AK, Crowgey EL, Chanock SJ, Greene MH, McGlynn KA, Nathanson K, Turnbull C, Wang Z, Devoto M, Barthold JS. Subphenotype meta-analysis of testicular cancer genome-wide association study data suggests a role for RBFOX family genes in cryptorchidism susceptibility. Human Reproduction (Oxford, England). PMID 29618007 DOI: 10.1093/Humrep/Dey066 |
0.387 |
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| 2018 |
Fang J, Jia J, Makowski M, Xu M, Wang Z, Zhang T, Hoskins JW, Choi J, Han Y, Zhang M, Thomas J, Kovacs M, Collins I, Dzyadyk M, Thompson A, ... ... Nathanson KL, et al. Publisher correction: Functional characterization of a multi-cancer risk locus on chr5p15.33 reveals regulation of TERT by ZNF148. Nature Communications. 9: 16159. PMID 29596408 DOI: 10.1038/Ncomms16159 |
0.351 |
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| 2018 |
Zhang G, Wu LW, Mender I, Barzily-Rokni M, Hammond MR, Ope O, Cheng C, Randell S, Sadek N, Beroard A, Xiao M, Tian T, Tan J, Saeed U, Sugarman E, ... ... Nathanson KL, et al. Induction of Telomere Dysfunction Prolongs Disease Control of Therapy-Resistant Melanoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 29563139 DOI: 10.1158/1078-0432.Ccr-17-2773 |
0.32 |
|
| 2018 |
Rebbeck TR, Friebel TM, Friedman E, Hamann U, Huo D, Kwong A, Olah E, Olopade OI, Solano AR, Teo SH, Thomassen M, Weitzel JN, Chan TL, Couch FJ, Goldgar DE, ... ... Nathanson KL, et al. Mutational Spectrum in a Worldwide Study of 29,700 Families with BRCA1 or BRCA2 Mutations. Human Mutation. PMID 29446198 DOI: 10.1002/Humu.23406 |
0.392 |
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| 2018 |
Rech AJ, Balli D, Mantero A, Ishwaran H, Nathanson KL, Stanger BZ, Vonderheide RH. Tumor immunity and survival as a function of alternative neopeptides in human cancer. Cancer Immunology Research. PMID 29339376 DOI: 10.1158/2326-6066.Cir-17-0559 |
0.34 |
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| 2018 |
Wang S, Qian F, Zheng Y, Ogundiran T, Ojengbede O, Zheng W, Blot W, Nathanson KL, Hennis A, Nemesure B, Ambs S, Olopade OI, Huo D. Genetic variants demonstrating flip-flop phenomenon and breast cancer risk prediction among women of African ancestry. Breast Cancer Research and Treatment. PMID 29302764 DOI: 10.1007/S10549-017-4638-1 |
0.403 |
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| 2018 |
Safonov AM, Speare V, Dolinsky JS, Yussuf A, Gau C, Nathanson K. Clinical and molecular characteristics of NF1 mutations identified on hereditary cancer multi-gene panels. Journal of Clinical Oncology. 36. DOI: 10.1200/Jco.2018.36.15_Suppl.E13612 |
0.402 |
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| 2018 |
Nead KT, Mitra N, Zhou W, Gillette RC, Clark D, Ebrahimzadeh JE, Long JM, Mckenna D, Powers J, Maxwell KN, Shah PD, Bradbury AR, Nathanson K, Domchek SM. Risk of pediatric malignancy in families known to carry BRCA1/2 mutations. Journal of Clinical Oncology. 36: 1535-1535. DOI: 10.1200/Jco.2018.36.15_Suppl.1535 |
0.454 |
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| 2018 |
Bradbury AR, Gaieski JB, Egleston BL, Patrick-Miller LJ, Chung W, Olopade OI, Maxwell KN, Walser S, Fetzer D, Brower J, Brandt AC, Clark D, DiGiovanni L, Long JM, Powers J, ... ... Nathanson K, et al. Interest in and outcomes with web-based education for return of genetic research results for inherited susceptibility to breast cancer. Journal of Clinical Oncology. 36: 1531-1531. DOI: 10.1200/Jco.2018.36.15_Suppl.1531 |
0.322 |
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| 2018 |
Aldubayan SH, Pyle LT, Loud JT, Greene MH, Sweeney C, Nathanson K, Allen EMV, Stewart DR, Lessel D. Inherited defects in checkpoint kinase 2 (CHEK2) to confer increased susceptibility to testicular germ cell tumors. Journal of Clinical Oncology. 36: 1515-1515. DOI: 10.1200/Jco.2018.36.15_Suppl.1515 |
0.428 |
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| 2018 |
Maxwell KN, Vijai J, Lilyquist J, Slavin TP, Kulkarni A, Vaccaro O, Wubbenhorst B, Neuhausen SL, Hart S, Ravichandran V, Thomas T, Hu C, Schrader KA, DeMichele A, Offit K, ... ... Nathanson K, et al. Inherited mutations in breast cancer patients with and without multiple primary cancers. Journal of Clinical Oncology. 36: 1503-1503. DOI: 10.1200/Jco.2018.36.15_Suppl.1503 |
0.5 |
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| 2018 |
Kraya AA, Maxwell KN, Wubbenhorst B, Wenz BM, Pluta J, Rech AJ, Lunceford N, Barrett A, Mitra N, Morrissette JJD, Nayak A, Feldman M, Domchek SM, Vonderheide RH, Nathanson KL. Abstract A22: Homologous recombination deficiency negatively predicts for immune infiltration and antitumor immune activity in breast tumors with BRCA1/2 alterations Molecular Cancer Research. 16. DOI: 10.1158/1557-3125.Advbc17-A22 |
0.472 |
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| 2017 |
Wang S, Zheng Y, Ogundiran TO, Ojengbede O, Zheng W, Nathanson KL, Nemesure B, Ambs S, Olopade OI, Huo D. Association of Pancreatic Cancer Susceptibility Variants with Risk of Breast Cancer in Women of European and African Ancestry. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. PMID 29254938 DOI: 10.1158/1055-9965.Epi-17-0755 |
0.474 |
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| 2017 |
Krepler C, Sproesser K, Brafford P, Beqiri M, Garman B, Xiao M, Shannan B, Watters A, Perego M, Zhang G, Vultur A, Yin X, Liu Q, Anastopoulos IN, Wubbenhorst B, ... ... Nathanson KL, et al. A Comprehensive Patient-Derived Xenograft Collection Representing the Heterogeneity of Melanoma. Cell Reports. 21: 1953-1967. PMID 29141225 DOI: 10.1016/J.Celrep.2017.10.021 |
0.333 |
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| 2017 |
Garman B, Anastopoulos IN, Krepler C, Brafford P, Sproesser K, Jiang Y, Wubbenhorst B, Amaravadi R, Bennett J, Beqiri M, Elder D, Flaherty KT, Frederick DT, Gangadhar TC, Guarino M, ... ... Nathanson KL, et al. Genetic and Genomic Characterization of 462 Melanoma Patient-Derived Xenografts, Tumor Biopsies, and Cell Lines. Cell Reports. 21: 1936-1952. PMID 29141224 DOI: 10.1016/J.Celrep.2017.10.052 |
0.415 |
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| 2017 |
Slavin TP, Maxwell KN, Lilyquist J, Vijai J, Neuhausen SL, Hart SN, Ravichandran V, Thomas T, Maria A, Villano D, Schrader KA, Moore R, Hu C, Wubbenhorst B, Wenz BM, ... ... Nathanson KL, et al. Erratum: Author Correction: The contribution of pathogenic variants in breast cancer susceptibility genes to familial breast cancer risk. Npj Breast Cancer. 3: 44. PMID 29119134 DOI: 10.1038/s41523-017-0046-2 |
0.332 |
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| 2017 |
Milne RL, Kuchenbaecker KB, Michailidou K, Beesley J, Kar S, Lindström S, Hui S, Lemaçon A, Soucy P, Dennis J, Jiang X, Rostamianfar A, Finucane H, Bolla MK, McGuffog L, ... ... Nathanson KL, et al. Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer. Nature Genetics. PMID 29058716 DOI: 10.1038/Ng.3785 |
0.487 |
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| 2017 |
Chen H, Jiang Y, Maxwell KN, Nathanson KL, Zhang N. ALLELE-SPECIFIC COPY NUMBER ESTIMATION BY WHOLE EXOME SEQUENCING. The Annals of Applied Statistics. 11: 1169-1192. PMID 28989557 DOI: 10.1214/17-Aoas1043 |
0.359 |
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| 2017 |
Wang S, Huo D, Kupfer S, Alleyne D, Ogundiran TO, Ojengbede O, Zheng W, Nathanson KL, Nemesure B, Ambs S, Olopade OI, Zheng Y. Genetic variation in the Vitamin D related pathway and breast cancer risk in women of African ancestry in the Root Consortium. International Journal of Cancer. PMID 28891071 DOI: 10.1002/Ijc.31038 |
0.401 |
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| 2017 |
Maxwell KN, Wubbenhorst B, Wenz BM, De Sloover D, Pluta J, Emery L, Barrett A, Kraya AA, Anastopoulos IN, Yu S, Jiang Y, Chen H, Zhang NR, Hackman N, D'Andrea K, ... ... Nathanson KL, et al. BRCA locus-specific loss of heterozygosity in germline BRCA1 and BRCA2 carriers. Nature Communications. 8: 319. PMID 28831036 DOI: 10.1038/S41467-017-00388-9 |
0.472 |
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| 2017 |
Wasserman JD, Tomlinson GE, Druker H, Kamihara J, Kohlmann WK, Kratz CP, Nathanson KL, Pajtler KW, Parareda A, Rednam SP, States LJ, Villani A, Walsh MF, Zelley K, Schiffman JD. Multiple Endocrine Neoplasia and Hyperparathyroid-Jaw Tumor Syndromes: Clinical Features, Genetics, and Surveillance Recommendations in Childhood. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 23: e123-e132. PMID 28674121 DOI: 10.1158/1078-0432.Ccr-17-0548 |
0.328 |
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| 2017 |
Achatz MI, Porter CC, Brugières L, Druker H, Frebourg T, Foulkes WD, Kratz CP, Kuiper RP, Hansford JR, Hernandez HS, Nathanson KL, Kohlmann WK, Doros L, Onel K, Schneider KW, et al. Cancer Screening Recommendations and Clinical Management of Inherited Gastrointestinal Cancer Syndromes in Childhood. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 23: e107-e114. PMID 28674119 DOI: 10.1158/1078-0432.Ccr-17-0790 |
0.405 |
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| 2017 |
Slavin TP, Maxwell KN, Lilyquist J, Vijai J, Neuhausen SL, Hart SN, Ravichandran V, Thomas T, Maria A, Villano D, Schrader KA, Moore R, Hu C, Wubbenhorst B, Wenz BM, ... ... Nathanson KL, et al. The contribution of pathogenic variants in breast cancer susceptibility genes to familial breast cancer risk. Npj Breast Cancer. 3: 22. PMID 28649662 DOI: 10.1038/s41523-017-0024-8 |
0.416 |
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| 2017 |
Murphy ME, Liu S, Yao S, Huo D, Liu Q, Dolfi SC, Hirshfield KM, Hong CC, Hu Q, Olshan AF, Ogundiran TO, Adebamowo C, Domchek SM, Nathanson KL, Nemesure B, et al. A functionally significant SNP in TP53 and breast cancer risk in African-American women. Npj Breast Cancer. 3: 5. PMID 28649645 DOI: 10.1038/s41523-017-0007-9 |
0.343 |
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| 2017 |
Villani A, Greer MC, Kalish JM, Nakagawara A, Nathanson KL, Pajtler KW, Pfister SM, Walsh MF, Wasserman JD, Zelley K, Kratz CP. Recommendations for Cancer Surveillance in Individuals with RASopathies and Other Rare Genetic Conditions with Increased Cancer Risk. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 23: e83-e90. PMID 28620009 DOI: 10.1158/1078-0432.Ccr-17-0631 |
0.406 |
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| 2017 |
Rednam SP, Erez A, Druker H, Janeway KA, Kamihara J, Kohlmann WK, Nathanson KL, States LJ, Tomlinson GE, Villani A, Voss SD, Schiffman JD, Wasserman JD. Von Hippel-Lindau and Hereditary Pheochromocytoma/Paraganglioma Syndromes: Clinical Features, Genetics, and Surveillance Recommendations in Childhood. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 23: e68-e75. PMID 28620007 DOI: 10.1158/1078-0432.Ccr-17-0547 |
0.356 |
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| 2017 |
Shaffer SM, Dunagin MC, Torborg SR, Torre EA, Emert B, Krepler C, Beqiri M, Sproesser K, Brafford PA, Xiao M, Eggan E, Anastopoulos IN, Vargas-Garcia CA, Singh A, Nathanson KL, et al. Rare cell variability and drug-induced reprogramming as a mode of cancer drug resistance. Nature. PMID 28607484 DOI: 10.1038/Nature22794 |
0.336 |
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| 2017 |
Wang Z, McGlynn KA, Rajpert-De Meyts E, Bishop DT, Chung CC, Dalgaard MD, Greene MH, Gupta R, Grotmol T, Haugen TB, Karlsson R, Litchfield K, Mitra N, Nielsen K, Pyle LC, ... ... Nathanson KL, et al. Meta-analysis of five genome-wide association studies identifies multiple new loci associated with testicular germ cell tumor. Nature Genetics. PMID 28604732 DOI: 10.1038/Ng.3879 |
0.374 |
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| 2017 |
Wang S, Huo D, Ogundiran TO, Ojengbede O, Zheng W, Nathanson KL, Nemesure B, Ambs S, Olopade OI, Zheng Y. Association of breast cancer risk and the mTOR pathway in women of African ancestry in "The Root" Consortium. Carcinogenesis. PMID 28582508 DOI: 10.1093/Carcin/Bgx055 |
0.469 |
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| 2017 |
Pyle LC, Nathanson KL. A practical guide for evaluating gonadal germ cell tumor predisposition in differences of sex development. American Journal of Medical Genetics. Part C, Seminars in Medical Genetics. PMID 28544305 DOI: 10.1002/Ajmg.C.31562 |
0.374 |
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| 2017 |
Shah PD, Nathanson KL. Application of Panel-Based Tests for Inherited Risk of Cancer. Annual Review of Genomics and Human Genetics. PMID 28504904 DOI: 10.1146/Annurev-Genom-091416-035305 |
0.431 |
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| 2017 |
Lecarpentier J, Silvestri V, Kuchenbaecker KB, Barrowdale D, Dennis J, McGuffog L, Soucy P, Leslie G, Rizzolo P, Navazio AS, Valentini V, Zelli V, Lee A, Amin Al Olama A, Tyrer JP, ... ... Nathanson KL, et al. Prediction of Breast and Prostate Cancer Risks in Male BRCA1 and BRCA2 Mutation Carriers Using Polygenic Risk Scores. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. JCO2016694935. PMID 28448241 DOI: 10.1200/Jco.2016.69.4935 |
0.47 |
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| 2017 |
Fang J, Jia J, Makowski M, Xu M, Wang Z, Zhang T, Hoskins JW, Choi J, Han Y, Zhang M, Thomas J, Kovacs M, Collins I, Dzyadyk M, Thompson A, ... ... Nathanson KL, et al. Functional characterization of a multi-cancer risk locus on chr5p15.33 reveals regulation of TERT by ZNF148. Nature Communications. 8: 15034. PMID 28447668 DOI: 10.1038/Ncomms15034 |
0.382 |
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| 2017 |
Ng MCY, Graff M, Lu Y, Justice AE, Mudgal P, Liu CT, Young K, Yanek LR, Feitosa MF, Wojczynski MK, Rand K, Brody JA, Cade BE, Dimitrov L, Duan Q, ... ... Nathanson KL, et al. Discovery and fine-mapping of adiposity loci using high density imputation of genome-wide association studies in individuals of African ancestry: African ancestry anthropometry genetics consortium. Plos Genetics. 13: e1006719. PMID 28430825 DOI: 10.1371/Journal.Pgen.1006719 |
0.319 |
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| 2017 |
Feng Y, Rhie SK, Huo D, Ruiz-Narvaez EA, Haddad SA, Ambrosone CB, John EM, Bernstein L, Zheng W, Hu JJ, Ziegler RG, Nyante S, Bandera EV, Ingles SA, Press MF, ... ... Nathanson KL, et al. Characterizing Genetic Susceptibility to Breast Cancer in Women of African Ancestry. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. PMID 28377418 DOI: 10.1158/1055-9965.Epi-16-0567 |
0.427 |
|
| 2017 |
Fishbein L, Leshchiner I, Walter V, Danilova L, Robertson AG, Johnson AR, Lichtenberg TM, Murray BA, Ghayee HK, Else T, Ling S, Jefferys SR, de Cubas AA, Wenz B, Korpershoek E, ... ... Nathanson KL, et al. Comprehensive Molecular Characterization of Pheochromocytoma and Paraganglioma. Cancer Cell. PMID 28162975 DOI: 10.1016/J.Ccell.2017.01.001 |
0.372 |
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| 2017 |
Walker LC, Marquart L, Pearson JF, Wiggins GA, O'Mara TA, Parsons MT, Barrowdale D, McGuffog L, Dennis J, Benitez J, Slavin TP, Radice P, Frost D, ... ... Nathanson KL, et al. Evaluation of copy-number variants as modifiers of breast and ovarian cancer risk for BRCA1 pathogenic variant carriers. European Journal of Human Genetics : Ejhg. PMID 28145423 DOI: 10.1038/Ejhg.2016.203 |
0.503 |
|
| 2017 |
George E, Kim H, Krepler C, Wenz B, Makvandi M, Tanyi JL, Brown E, Zhang R, Brafford P, Jean S, Mach RH, Lu Y, Mills GB, Herlyn M, Morgan M, ... ... Nathanson KL, et al. A patient-derived-xenograft platform to study BRCA-deficient ovarian cancers. Jci Insight. 2: e89760. PMID 28097235 DOI: 10.1172/Jci.Insight.89760 |
0.423 |
|
| 2017 |
Lee KM, Wang S, Huo D, Ogundiran TO, Ojengbede O, Zheng W, Nathanson KL, Nemesure B, Ambs S, Zheng Y, Olopade OI. Association of breast cancer risk in women of African ancestry with genetic variants in the TET-related DNA demethylation pathway. Journal of Clinical Oncology. 35. DOI: 10.1200/Jco.2017.35.15_Suppl.E13015 |
0.418 |
|
| 2017 |
Kraya A, Maxwell KN, Wenz BM, Wubbenhorst B, Sloover DD, Lunceford N, Barrett A, Morrissette JD, Feldman M, Vonderheide RH, Domcheck SM, Nathanson KL. Abstract A12: Analysis of tumor immunogenicity in germline BRCA1/2 mutation associated breast and ovarian cancers Cancer Immunology Research. 5. DOI: 10.1158/2326-6074.Tumimm16-A12 |
0.486 |
|
| 2017 |
Wang S, Qian F, Zheng Y, Ogundiran T, Ojengbede O, Zheng W, Blot W, Nathanson K, Hennis A, Nemesure B, Ambs S, Olopade O, Huo D. Abstract P5-09-02: Breast cancer risk prediction using a polygenic risk score in women of African ancestry: Findings from GWAS in breast cancer in the African diaspora Cancer Research. 77. DOI: 10.1158/1538-7445.Sabcs16-P5-09-02 |
0.431 |
|
| 2017 |
Maxwell KN, Slavin TP, Lilyquist JM, Vijai J, Neuhausen SL, Hart SN, Ravichandran V, Thomas T, Maria A, Schrader KA, Moore R, Hu C, Wubbenhorst B, Wenz BM, D'Andrea K, ... ... Nathanson KL, et al. Abstract 4265: Risks of familial breast cancer associated with known and proposed breast cancer susceptibility genes Epidemiology. 77: 4265-4265. DOI: 10.1158/1538-7445.Am2017-4265 |
0.45 |
|
| 2017 |
Kraya A, Maxwell KN, Wenz BM, Wubbenhorst B, Lunceford N, Barrett A, Morrissette JJ, Feldman MD, Domchek SM, Vonderheide RH, Nathanson KL. Abstract 3691: Analysis of germline BRCA1/2 mutation associated breast and ovarian tumors reveals distinct pathways of immunosuppression Immunology. 77: 3691-3691. DOI: 10.1158/1538-7445.Am2017-3691 |
0.457 |
|
| 2017 |
Wang S, Zheng Y, Ogundiran TO, Ojengbede O, Zheng W, Nathanson KL, Nemesure B, Ambs S, Huo D, Olopade OI. Abstract 1312: Genetic variation in the Hippo pathway and breast cancer risk in women of African ancestry in the ROOT Consortium Epidemiology. 77: 1312-1312. DOI: 10.1158/1538-7445.Am2017-1312 |
0.405 |
|
| 2016 |
Huo D, Feng Y, Haddad S, Zheng Y, Yao S, Han YJ, Ogundiran TO, Adebamowo C, Ojengbede O, Falusi AG, Zheng W, Blot W, Cai Q, Signorello L, John EM, ... ... Nathanson KL, et al. Genome-wide association studies in women of African ancestry identified 3q26.21 as a novel susceptibility locus for oestrogen receptor negative breast cancer. Human Molecular Genetics. 25: 4835-4846. PMID 28171663 DOI: 10.1093/Hmg/Ddw305 |
0.46 |
|
| 2016 |
Pyle LC, Nathanson KL. Genetic changes associated with testicular cancer susceptibility. Seminars in Oncology. 43: 575-581. PMID 27899190 DOI: 10.1053/J.Seminoncol.2016.08.004 |
0.437 |
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| 2016 |
Rebbeck TR, Friebel TM, Mitra N, Wan F, Chen S, Andrulis IL, Apostolou P, Arnold N, Arun BK, Barrowdale D, Benitez J, Berger R, Berthet P, Borg A, Buys SS, ... ... Nathanson KL, et al. Inheritance of deleterious mutations at both BRCA1 and BRCA2 in an international sample of 32,295 women. Breast Cancer Research : Bcr. 18: 112. PMID 27836010 DOI: 10.1186/S13058-016-0768-3 |
0.384 |
|
| 2016 |
Hamdi Y, Soucy P, Kuchenbaeker KB, Pastinen T, Droit A, Lemaçon A, Adlard J, Aittomäki K, Andrulis IL, Arason A, Arnold N, Arun BK, Azzollini J, Bane A, Barjhoux L, ... ... Nathanson KL, et al. Association of breast cancer risk in BRCA1 and BRCA2 mutation carriers with genetic variants showing differential allelic expression: identification of a modifier of breast cancer risk at locus 11q22.3. Breast Cancer Research and Treatment. PMID 27796716 DOI: 10.1007/S10549-016-4018-2 |
0.52 |
|
| 2016 |
Krepler C, Xiao M, Samanta M, Vultur A, Chen HY, Brafford P, Reyes-Uribe PI, Halloran M, Chen T, He X, Hristova D, Liu Q, Samatar AA, Davies MA, Nathanson KL, et al. Targeting Notch enhances the efficacy of ERK inhibitors in BRAF-V600E melanoma. Oncotarget. PMID 27655717 DOI: 10.18632/Oncotarget.12078 |
0.305 |
|
| 2016 |
Vijai J, Topka S, Villano D, Ravichandran V, Maxwell KN, Maria A, Thomas T, Gaddam P, Lincoln A, Kazzaz S, Wenz B, Carmi S, Schrader KA, Hart SN, Lipkin SM, ... ... Nathanson KL, et al. A recurrent ERCC3 truncating mutation confers moderate risk for breast cancer. Cancer Discovery. PMID 27655433 DOI: 10.1158/2159-8290.Cd-16-0487 |
0.511 |
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| 2016 |
Balmaña J, Digiovanni L, Gaddam P, Walsh MF, Joseph V, Stadler ZK, Nathanson KL, Garber JE, Couch FJ, Offit K, Robson ME, Domchek SM. Conflicting Interpretation of Genetic Variants and Cancer Risk by Commercial Laboratories as Assessed by the Prospective Registry of Multiplex Testing. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. PMID 27621404 DOI: 10.1200/Jco.2016.68.4316 |
0.375 |
|
| 2016 |
Lawrenson K, Kar S, McCue K, Kuchenbaeker K, Michailidou K, Tyrer J, Beesley J, Ramus SJ, Li Q, Delgado MK, Lee JM, Aittomäki K, Andrulis IL, Anton-Culver H, Arndt V, ... ... Nathanson KL, et al. Functional mechanisms underlying pleiotropic risk alleles at the 19p13.1 breast-ovarian cancer susceptibility locus. Nature Communications. 7: 12675. PMID 27601076 DOI: 10.1038/ncomms12675 |
0.336 |
|
| 2016 |
Huo D, Feng Y, Haddad S, Zheng Y, Yao S, Han YJ, Ogundiran TO, Adebamowo C, Ojengbede O, Falusi AG, Zheng W, Blot W, Cai Q, Signorello L, John EM, ... ... Nathanson KL, et al. Genome-wide Association Studies in Women of African Ancestry Identified 3q26.21 as a Novel Susceptibility Locus for Estrogen Receptor Negative Breast Cancer. Human Molecular Genetics. PMID 27594435 DOI: 10.1093/hmg/ddw305 |
0.356 |
|
| 2016 |
Maxwell KN, Domchek SM, Nathanson KL, Robson ME. Population Frequency of Germline BRCA1/2 Mutations. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. PMID 27551127 DOI: 10.1200/Jco.2016.67.0554 |
0.326 |
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| 2016 |
Vigorito E, Kuchenbaecker KB, Beesley J, Adlard J, Agnarsson BA, Andrulis IL, Arun BK, Barjhoux L, Belotti M, Benitez J, Berger A, Bojesen A, Bonanni B, Brewer C, Caldes T, ... ... Nathanson KL, et al. Fine-Scale Mapping at 9p22.2 Identifies Candidate Causal Variants That Modify Ovarian Cancer Risk in BRCA1 and BRCA2 Mutation Carriers. Plos One. 11: e0158801. PMID 27463617 DOI: 10.1371/Journal.Pone.0158801 |
0.488 |
|
| 2016 |
Zeng C, Guo X, Long J, Kuchenbaecker KB, Droit A, Michailidou K, Ghoussaini M, Kar S, Freeman A, Hopper JL, Milne RL, Bolla MK, Wang Q, Dennis J, Agata S, ... ... Nathanson KL, et al. Identification of independent association signals and putative functional variants for breast cancer risk through fine-scale mapping of the 12p11 locus. Breast Cancer Research : Bcr. 18: 64. PMID 27459855 DOI: 10.1186/S13058-016-0718-0 |
0.434 |
|
| 2016 |
Shannan B, Watters A, Chen Q, Mollin S, Dörr M, Meggers E, Xu X, Gimotty PA, Perego M, Li L, Benci J, Krepler C, Brafford P, Zhang J, Wei Z, ... ... Nathanson KL, et al. PIM kinases as therapeutic targets against advanced melanoma. Oncotarget. PMID 27448973 DOI: 10.18632/Oncotarget.10703 |
0.305 |
|
| 2016 |
Qian F, Feng Y, Zheng Y, Ogundiran TO, Ojengbede O, Zheng W, Blot W, Ambrosone CB, John EM, Bernstein L, Hu JJ, Ziegler RG, Nyante S, Bandera EV, Ingles SA, ... ... Nathanson KL, et al. Genetic variants in microRNA and microRNA biogenesis pathway genes and breast cancer risk among women of African ancestry. Human Genetics. PMID 27380242 DOI: 10.1007/S00439-016-1707-1 |
0.396 |
|
| 2016 |
Shu CA, Pike MC, Jotwani AR, Friebel TM, Soslow RA, Levine DA, Nathanson KL, Konner JA, Arnold AG, Bogomolniy F, Dao F, Olvera N, Bancroft EK, Goldfrank DJ, Stadler ZK, et al. Uterine Cancer After Risk-Reducing Salpingo-oophorectomy Without Hysterectomy in Women With BRCA Mutations. Jama Oncology. PMID 27367496 DOI: 10.1001/Jamaoncol.2016.1820 |
0.416 |
|
| 2016 |
Tung N, Domchek SM, Stadler Z, Nathanson KL, Couch F, Garber JE, Offit K, Robson ME. Counselling framework for moderate-penetrance cancer-susceptibility mutations. Nature Reviews. Clinical Oncology. PMID 27296296 DOI: 10.1038/Nrclinonc.2016.90 |
0.461 |
|
| 2016 |
Jean S, Li J, Katsaros D, Wubbenhorst B, Maxwell KN, Fishbein L, McLane MW, Benedetto C, Canuto EM, Mitra N, Zhang L, Nathanson KL, Tanyi JL. Paclitaxel is necessary for improved survival in epithelial ovarian cancers with homologous recombination gene mutations. Oncotarget. PMID 27191893 DOI: 10.18632/Oncotarget.9373 |
0.423 |
|
| 2016 |
Maxwell KN, Hart SN, Vijai J, Schrader KA, Slavin TP, Thomas T, Wubbenhorst B, Ravichandran V, Moore RM, Hu C, Guidugli L, Wenz B, Domchek SM, Robson ME, Szabo C, ... ... Nathanson KL, et al. Evaluation of ACMG-Guideline-Based Variant Classification of Cancer Susceptibility and Non-Cancer-Associated Genes in Families Affected by Breast Cancer. American Journal of Human Genetics. 98: 801-17. PMID 27153395 DOI: 10.1016/J.Ajhg.2016.02.024 |
0.499 |
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| 2016 |
Scelo G, Hofmann JN, Banks RE, Bigot P, Bhatt RS, Cancel-Tassin G, Chew SK, Creighton CJ, Cussenot O, Davis IJ, Escudier B, Frayling TM, Häggström C, Hildebrandt MA, Holcatova I, ... ... Nathanson KL, et al. International cancer seminars - A focus on kidney cancer. Annals of Oncology : Official Journal of the European Society For Medical Oncology / Esmo. PMID 27130845 DOI: 10.1093/Annonc/Mdw186 |
0.376 |
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| 2016 |
Couch FJ, Kuchenbaecker KB, Michailidou K, Mendoza-Fandino GA, Nord S, Lilyquist J, Olswold C, Hallberg E, Agata S, Ahsan H, Aittomäki K, Ambrosone C, Andrulis IL, Anton-Culver H, Arndt V, ... ... Nathanson KL, et al. Identification of four novel susceptibility loci for oestrogen receptor negative breast cancer. Nature Communications. 7: 11375. PMID 27117709 DOI: 10.1038/Ncomms11375 |
0.466 |
|
| 2016 |
Walsh MF, Nathanson KL, Couch FJ, Offit K. Genomic Biomarkers for Breast Cancer Risk. Advances in Experimental Medicine and Biology. 882: 1-32. PMID 26987529 DOI: 10.1007/978-3-319-22909-6_1 |
0.449 |
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| 2016 |
Dunning AM, Michailidou K, Kuchenbaecker KB, Thompson D, French JD, Beesley J, Healey CS, Kar S, Pooley KA, Lopez-Knowles E, Dicks E, Barrowdale D, Sinnott-Armstrong NA, Sallari RC, Hillman KM, ... ... Nathanson KL, et al. Breast cancer risk variants at 6q25 display different phenotype associations and regulate ESR1, RMND1 and CCDC170. Nature Genetics. PMID 26928228 DOI: 10.1038/Ng.3521 |
0.419 |
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| 2016 |
Sargen MR, Merrill SL, Chu EY, Nathanson KL. CDKN2A mutations with p14 loss predisposing to multiple nerve sheath tumours, melanoma, dysplastic naevi and internal malignancies: a case series and review of the literature. British Journal of Dermatology. 175: 785-789. PMID 26876133 DOI: 10.1111/Bjd.14485 |
0.392 |
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| 2016 |
Silvestri V, Barrowdale D, Mulligan AM, Neuhausen SL, Fox S, Karlan BY, Mitchell G, James P, Thull DL, Zorn KK, Carter NJ, Nathanson KL, Domchek SM, Rebbeck TR, Ramus SJ, et al. Male breast cancer in BRCA1 and BRCA2 mutation carriers: pathology data from the Consortium of Investigators of Modifiers of BRCA1/2. Breast Cancer Research : Bcr. 18: 15. PMID 26857456 DOI: 10.1186/S13058-016-0671-Y |
0.471 |
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| 2016 |
Meeks HD, Song H, Michailidou K, Bolla MK, Dennis J, Wang Q, Barrowdale D, Frost D, McGuffog L, Ellis S, Feng B, Buys SS, Hopper JL, Southey MC, ... ... Nathanson KL, et al. BRCA2 Polymorphic Stop Codon K3326X and the Risk of Breast, Prostate, and Ovarian Cancers. Journal of the National Cancer Institute. 108. PMID 26586665 DOI: 10.1093/Jnci/Djv315 |
0.478 |
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| 2016 |
Offit K, Schrader KA, Maxwell KN, Vijai J, Hart S, Thomas T, Wubbenhorst B, Ravichandran V, Moore R, Hu C, Lilyquist J, Shimelis H, Slavin TP, Domchek SM, Robson ME, ... ... Nathanson KL, et al. Cancer susceptibility mutations in individuals with breast and ovarian cancer using next-generation sequencing. Journal of Clinical Oncology. 34: 1515-1515. DOI: 10.1200/Jco.2016.34.15_Suppl.1515 |
0.494 |
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| 2016 |
George E, Kim H, Tanyi J, Ragland R, Brown E, Zhang R, Brafford P, Sproesser K, Beqiri M, Vultur A, Krepler C, Weis B, Nathanson K, Lu Y, Mills G, et al. Abstract A02: A novel orthotopic ovarian patient derived xenograft model platform to investigate novel therapies for BRCA deficient ovarian cancers Clinical Cancer Research. 22. DOI: 10.1158/1557-3265.Pdx16-A02 |
0.412 |
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| 2016 |
Krepler C, Sproesser K, Beqiri M, Xiao M, Brafford P, Xu W, Garman B, Wargo J, Davies MA, Frederick DT, Flaherty KT, Hoon D, Bennett JJ, Guarino M, Petrelli NJ, ... ... Nathanson KL, et al. Abstract A01: A comprehensive collection of patient derived xenografts of human melanoma with clinical, genomic, and biological characterization Clinical Cancer Research. 22. DOI: 10.1158/1557-3265.Pdx16-A01 |
0.391 |
|
| 2016 |
Lilyquist J, Kraft P, Hart SN, Hallberg EJ, Hu C, Moore R, Gnanaolivu R, Domchek SM, Weitzel JN, Nathanson KL, Goldgar DE, Couch FJ. Abstract 810: The CARRIERS consortium: Establishing refined breast cancer risk estimates in known predisposition genes Cancer Research. 76: 810-810. DOI: 10.1158/1538-7445.Am2016-810 |
0.509 |
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| 2016 |
Vijai J, Topka S, Maxwell K, Ravichandran V, Thomas T, Villano D, Maria A, Gaddam P, Lincoln A, Hart S, Neuhausen S, Robson M, Weitzel J, Daly M, Nathanson K, et al. Abstract 796: ERCC3 R109X is a moderate risk breast cancer risk variant in Ashkenazi Jews Cancer Research. 76: 796-796. DOI: 10.1158/1538-7445.Am2016-796 |
0.53 |
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| 2016 |
Maxwell KN, Hart SN, Vijai J, Schrader KA, Thomas T, Wubbenhorst B, Ravichandran V, Moore RM, Hu C, Guidugli L, Wenz B, Slavin TP, Domchek SM, Robson ME, Szabo C, ... ... Nathanson KL, et al. Abstract 5220: Evaluation of ACMG guideline classified variants in 180 cancer and incidental non-cancer genes in families with breast/ovarian cancer Epidemiology. 76: 5220-5220. DOI: 10.1158/1538-7445.Am2016-5220 |
0.439 |
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| 2016 |
George E, Kim H, Tanyi J, Ragland R, Zhang R, Bradford P, Krepler C, Nathanson K, Wenz B, Lu Y, Mills G, Morgan M, Simpkins F. Abstract 4835: Targeting the ATR/CHK1 axis in combination with PARP inhibition is more effective than PARP inhibition alone in BRCA mutant models Cancer Research. 76: 4835-4835. DOI: 10.1158/1538-7445.Am2016-4835 |
0.406 |
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| 2016 |
Kraya AA, Maxwell KN, Wenz BM, Wubbenhorst B, DeSloover D, Lunceford N, Morrissette JD, Feldman M, Vonderheide RH, Domchek SM, Nathanson KL. Abstract 4511: Characterization of tumor neoantigen repertoire in patients with germline BRCA1/2 mutations Cancer Research. 76: 4511-4511. DOI: 10.1158/1538-7445.Am2016-4511 |
0.432 |
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| 2015 |
Yang RL, Mick R, Lee K, Graves HL, Nathanson KL, Domchek SM, Kelz RR, Zhang PJ, Czerniecki BJ. DCIS in BRCA1 and BRCA2 mutation carriers: prevalence, phenotype, and expression of oncodrivers C-MET and HER3. Journal of Translational Medicine. 13: 335. PMID 26496879 DOI: 10.1186/S12967-015-0698-3 |
0.471 |
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| 2015 |
Pathak A, Stewart DR, Faucz FR, Xekouki P, Bass S, Vogt A, Zhang X, Boland J, Yeager M, Loud JT, Nathanson KL, McGlynn KA, Stratakis CA, Greene MH, Mirabello L. Rare inactivating PDE11A variants associated with testicular germ cell tumors. Endocrine-Related Cancer. 22: 909-17. PMID 26459559 DOI: 10.1530/Erc-15-0034 |
0.428 |
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| 2015 |
Hart SN, Maxwell KN, Thomas T, Ravichandran V, Wubberhorst B, Klein RJ, Schrader K, Szabo C, Weitzel JN, Neuhausen SL, Nathanson K, Offit K, Couch FJ, Vijai J. Collaborative science in the next-generation sequencing era: a viewpoint on how to combine exome sequencing data across sites to identify novel disease susceptibility genes. Briefings in Bioinformatics. PMID 26358132 DOI: 10.1093/Bib/Bbv075 |
0.338 |
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| 2015 |
Wilson MA, Zhao F, Khare S, D'Andrea K, Wubbenhorst B, Roszik J, Woodman SE, Rimm DL, Kirkwood JM, Kluger HM, Schuchter LM, Lee SJ, Flaherty KT, Nathanson KL. Copy number changes are associated with response to treatment with carboplatin, paclitaxel, and sorafenib in melanoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 26307133 DOI: 10.1158/1078-0432.Ccr-15-1162 |
0.337 |
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| 2015 |
Easton DF, Pharoah PD, Antoniou AC, Tischkowitz M, Tavtigian SV, Nathanson KL, Devilee P, Meindl A, Couch FJ, Southey M, Goldgar DE, Evans DG, Chenevix-Trench G, Rahman N, Robson M, et al. Gene-panel sequencing and the prediction of breast-cancer risk. The New England Journal of Medicine. 372: 2243-57. PMID 26014596 DOI: 10.1056/Nejmsr1501341 |
0.457 |
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| 2015 |
Hollestelle A, van der Baan FH, Berchuck A, Johnatty SE, Aben KK, Agnarsson BA, Aittomäki K, Alducci E, Andrulis IL, Anton-Culver H, Antonenkova NN, Antoniou AC, Apicella C, Arndt V, ... ... Nathanson KL, et al. No clinical utility of KRAS variant rs61764370 for ovarian or breast cancer. Gynecologic Oncology. PMID 25940428 DOI: 10.1016/J.Ygyno.2015.04.034 |
0.448 |
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| 2015 |
Blein S, Bardel C, Danjean V, McGuffog L, Healey S, Barrowdale D, Lee A, Dennis J, Kuchenbaecker KB, Soucy P, Terry MB, Chung WK, Goldgar DE, Buys SS, ... ... Nathanson KL, et al. An original phylogenetic approach identified mitochondrial haplogroup T1a1 as inversely associated with breast cancer risk in BRCA2 mutation carriers. Breast Cancer Research : Bcr. 17: 61. PMID 25925750 DOI: 10.1186/S13058-015-0567-2 |
0.449 |
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| 2015 |
Rebbeck TR, Mitra N, Wan F, Sinilnikova OM, Healey S, McGuffog L, Mazoyer S, Chenevix-Trench G, Easton DF, Antoniou AC, Nathanson KL, Laitman Y, Kushnir A, Paluch-Shimon S, et al. Association of type and location of BRCA1 and BRCA2 mutations with risk of breast and ovarian cancer. Jama. 313: 1347-61. PMID 25849179 DOI: 10.1001/Jama.2014.5985 |
0.483 |
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| 2015 |
Bradbury AR, Patrick-Miller LJ, Egleston BL, DiGiovanni L, Brower J, Harris D, Stevens EM, Maxwell KN, Kulkarni A, Chavez T, Brandt A, Long JM, Powers J, Stopfer JE, Nathanson KL, et al. Patient feedback and early outcome data with a novel tiered-binned model for multiplex breast cancer susceptibility testing. Genetics in Medicine : Official Journal of the American College of Medical Genetics. PMID 25834950 DOI: 10.1038/Gim.2015.19 |
0.397 |
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| 2015 |
Blanco I, Kuchenbaecker K, Cuadras D, Wang X, Barrowdale D, de Garibay GR, Librado P, Sánchez-Gracia A, Rozas J, Bonifaci N, McGuffog L, Pankratz VS, Islam A, Mateo F, Berenguer A, ... ... Nathanson KL, et al. Assessing associations between the AURKA-HMMR-TPX2-TUBG1 functional module and breast cancer risk in BRCA1/2 mutation carriers. Plos One. 10: e0120020. PMID 25830658 DOI: 10.1371/Journal.Pone.0120020 |
0.496 |
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| 2015 |
Fishbein L, Khare S, Wubbenhorst B, DeSloover D, D'Andrea K, Merrill S, Cho NW, Greenberg RA, Else T, Montone K, LiVolsi V, Fraker D, Daber R, Cohen DL, Nathanson KL. Whole-exome sequencing identifies somatic ATRX mutations in pheochromocytomas and paragangliomas. Nature Communications. 6: 6140. PMID 25608029 DOI: 10.1038/Ncomms7140 |
0.381 |
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| 2015 |
Kuchenbaecker KB, Ramus SJ, Tyrer J, Lee A, Shen HC, Beesley J, Lawrenson K, McGuffog L, Healey S, Lee JM, Spindler TJ, Lin YG, Pejovic T, Bean Y, Li Q, ... ... Nathanson KL, et al. Identification of six new susceptibility loci for invasive epithelial ovarian cancer. Nature Genetics. 47: 164-71. PMID 25581431 DOI: 10.1038/ng.3185 |
0.393 |
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| 2015 |
Peterlongo P, Chang-Claude J, Moysich KB, Rudolph A, Schmutzler RK, Simard J, Soucy P, Eeles RA, Easton DF, Hamann U, Wilkening S, Chen B, Rookus MA, Schmidt MK, van der Baan FH, ... ... Nathanson KL, et al. Candidate genetic modifiers for breast and ovarian cancer risk in BRCA1 and BRCA2 mutation carriers. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 24: 308-16. PMID 25336561 DOI: 10.1158/1055-9965.Epi-14-0532 |
0.493 |
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| 2015 |
Bradbury AR, Patrick-Miller L, Long J, Powers J, Stopfer J, Forman A, Rybak C, Mattie K, Brandt A, Chambers R, Chung WK, Churpek J, Daly MB, Digiovanni L, Farengo-Clark D, ... ... Nathanson KL, et al. Development of a tiered and binned genetic counseling model for informed consent in the era of multiplex testing for cancer susceptibility. Genetics in Medicine : Official Journal of the American College of Medical Genetics. 17: 485-92. PMID 25297947 DOI: 10.1038/Gim.2014.134 |
0.338 |
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| 2015 |
Gunnarsson O, Hwang W, Squillante CM, Nathanson KL, Stadtmauer EA, Vaughn DJ. Risk-stratified treatment of patients with metastatic germ cell tumor with progression after first-line therapy. Journal of Clinical Oncology. 33: 398-398. DOI: 10.1200/Jco.2015.33.7_Suppl.398 |
0.326 |
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| 2015 |
Bradbury AR, Patrick-Miller LJ, Egleston BL, Maxwell KN, Brandt A, Brower J, Digiovanni L, Long JM, Powers J, Stopfer J, Nathanson KL, Domchek SM. Interest in and outcomes with return of individual genetic research results for inherited susceptibility to breast cancer. Journal of Clinical Oncology. 33. DOI: 10.1200/Jco.2015.33.15_Suppl.E12503 |
0.364 |
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| 2015 |
McAndrew NP, Maxwell KN, Stopfer J, Powers J, Brandt AC, Long JM, Nathanson KL, Domchek SM. Oncotype DX scores in BRCA1 and BRCA2 associated breast cancer. Journal of Clinical Oncology. 33: 541-541. DOI: 10.1200/Jco.2015.33.15_Suppl.541 |
0.464 |
|
| 2015 |
Yam C, Stopfer J, Brandt A, Powers J, Long JM, Maxwell KN, Bradbury AR, Nathanson KL, Domchek SM. Impact of prior knowledge of mutation status on tumor stage in BRCA1/2 mutation carriers with newly diagnosed breast cancer. Journal of Clinical Oncology. 33: 1562-1562. DOI: 10.1200/Jco.2015.33.15_Suppl.1562 |
0.495 |
|
| 2015 |
Maxwell KN, Wenz B, Wubbenhorst B, D'Andrea KP, Garman B, Weathers B, Goodman N, Colameco C, Long JM, Powers J, Stopfer J, Bradbury AR, DeMichele A, Domchek SM, Nathanson KL. Characteristics of high risk breast cancer patients with mutations identified by multiplex panel testing. Journal of Clinical Oncology. 33: 1511-1511. DOI: 10.1200/Jco.2015.33.15_Suppl.1511 |
0.504 |
|
| 2015 |
Wang Z, Kanetsky PA, McGlynn KA, Bishop DT, Chung CC, Dalgaard MD, Grotmol T, Greene MH, Gupta R, Haugen TB, Litchfield K, Loud JT, Mitra N, Nielsen K, Turnbull C, ... ... Nathanson KL, et al. Abstract 843: Imputation and meta-analysis of five genome-wide association studies identify multiple new loci associated with testicular germ cell tumor Cancer Research. 75: 843-843. DOI: 10.1158/1538-7445.Am2015-843 |
0.396 |
|
| 2015 |
Wenz B, Maxwell KN, Wubbenhorst B, D'Andrea K, Garman B, Long JM, Powers J, Stopfer JE, Bradbury AR, DeMichele A, Domchek SM, Nathanson KL. Abstract 4663: Identification of germline variants in cancer susceptibility genes in patients with multiple primary cancers Cancer Research. 75: 4663-4663. DOI: 10.1158/1538-7445.Am2015-4663 |
0.496 |
|
| 2015 |
Brown KM, Fang J, Jia J, Wang Z, Makowski M, Zhang T, Hoskins J, Choi J, Han Y, Zhang M, Xu M, Kanetsky P, Thorkell A, Petersen GM, Nathanson KL, et al. Abstract 4610: Functional characterization of a multicancer risk locus on chr5p15.33 reveals regulation ofTERTby ZNF148 Cancer Research. 75: 4610-4610. DOI: 10.1158/1538-7445.Am2015-4610 |
0.44 |
|
| 2015 |
Jean S, Wubbenhorst B, Li J, Maxwell KN, Fishbein L, McLane MW, Mitra N, Zhang L, Nathanson KL, Tanyi JL. Abstract 4251: Paclitaxel is necessary for improved survival in epithelial ovarian cancers with somatic homologous recombination gene mutations Cancer Research. 75: 4251-4251. DOI: 10.1158/1538-7445.Am2015-4251 |
0.415 |
|
| 2015 |
Fishbein L, Khare S, Wubbenhorst B, LiVolsi V, Montone K, Fraker D, Cohen DL, Nathanson KL. Abstract 3892: Somatic genetic profiling in pheochromocytomas and paragangliomas Cancer Research. 75: 3892-3892. DOI: 10.1158/1538-7445.Am2015-3892 |
0.473 |
|
| 2015 |
Maxwell KN, Sloover DD, Wubbenhorst B, Wenz B, Lunceford N, Emery L, D'Andrea K, Daber RD, Feldman MD, Domchek SM, Nathanson KL. Abstract 2990: Evidence for diverse mechanisms of tumorigenesis in breast and ovarian tumors of BRCA1/2 carriers Cancer Research. 75: 2990-2990. DOI: 10.1158/1538-7445.Am2015-2990 |
0.482 |
|
| 2015 |
Krepler C, Xiao M, Sproesser K, Brafford P, Shannan B, Beqiri M, Xu W, Garman B, Nathanson KL, Xu X, Karakousis G, Mills GB, Lu Y, Caponigro G, Boehm M, et al. Abstract 2842: Personalized pre-clinical trials in BRAF inhibitor resistant patient derived xenograft models of melanoma identify c-Met as an effective second line combination therapy target Cancer Research. 75: 2842-2842. DOI: 10.1158/1538-7445.Am2015-2842 |
0.332 |
|
| 2014 |
Kuchenbaecker KB, Neuhausen SL, Robson M, Barrowdale D, McGuffog L, Mulligan AM, Andrulis IL, Spurdle AB, Schmidt MK, Schmutzler RK, Engel C, Wappenschmidt B, Nevanlinna H, Thomassen M, Southey M, ... ... Nathanson KL, et al. Associations of common breast cancer susceptibility alleles with risk of breast cancer subtypes in BRCA1 and BRCA2 mutation carriers. Breast Cancer Research : Bcr. 16: 3416. PMID 25919761 DOI: 10.1186/S13058-014-0492-9 |
0.448 |
|
| 2014 |
Spurdle AB, Couch FJ, Parsons MT, McGuffog L, Barrowdale D, Bolla MK, Wang Q, Healey S, Schmutzler R, Wappenschmidt B, Rhiem K, Hahnen E, Engel C, Meindl A, Ditsch N, ... ... Nathanson KL, et al. Refined histopathological predictors of BRCA1 and BRCA2 mutation status: a large-scale analysis of breast cancer characteristics from the BCAC, CIMBA, and ENIGMA consortia. Breast Cancer Research : Bcr. 16: 3419. PMID 25857409 DOI: 10.1186/S13058-014-0474-Y |
0.439 |
|
| 2014 |
Maxwell KN, Wubbenhorst B, D'Andrea K, Garman B, Long JM, Powers J, Rathbun K, Stopfer JE, Zhu J, Bradbury AR, Simon MS, DeMichele A, Domchek SM, Nathanson KL. Prevalence of mutations in a panel of breast cancer susceptibility genes in BRCA1/2-negative patients with early-onset breast cancer. Genetics in Medicine : Official Journal of the American College of Medical Genetics. PMID 25503501 DOI: 10.1038/Gim.2014.176 |
0.469 |
|
| 2014 |
Bajor DL, Xu X, Torigian DA, Mick R, Garcia LR, Richman LP, Desmarais C, Nathanson KL, Schuchter LM, Kalos M, Vonderheide RH. Immune activation and a 9-year ongoing complete remission following CD40 antibody therapy and metastasectomy in a patient with metastatic melanoma. Cancer Immunology Research. 2: 1051-8. PMID 25252722 DOI: 10.1158/2326-6066.Cir-14-0154 |
0.329 |
|
| 2014 |
Hu X, Feng Y, Zhang D, Zhao SD, Hu Z, Greshock J, Zhang Y, Yang L, Zhong X, Wang LP, Jean S, Li C, Huang Q, Katsaros D, Montone KT, ... ... Nathanson KL, et al. A functional genomic approach identifies FAL1 as an oncogenic long noncoding RNA that associates with BMI1 and represses p21 expression in cancer. Cancer Cell. 26: 344-57. PMID 25203321 DOI: 10.1016/J.Ccr.2014.07.009 |
0.387 |
|
| 2014 |
Domchek SM, Nathanson KL. Panel testing for inherited susceptibility to breast, ovarian, and colorectal cancer. Genetics in Medicine : Official Journal of the American College of Medical Genetics. 16: 827-9. PMID 24991876 DOI: 10.1038/Gim.2014.56 |
0.425 |
|
| 2014 |
Koster R, Mitra N, D'Andrea K, Vardhanabhuti S, Chung CC, Wang Z, Loren Erickson R, Vaughn DJ, Litchfield K, Rahman N, Greene MH, McGlynn KA, Turnbull C, Chanock SJ, Nathanson KL, et al. Pathway-based analysis of GWAs data identifies association of sex determination genes with susceptibility to testicular germ cell tumors. Human Molecular Genetics. 23: 6061-8. PMID 24943593 DOI: 10.1093/Hmg/Ddu305 |
0.332 |
|
| 2014 |
Wilson MA, Zhao F, Letrero R, D'Andrea K, Rimm DL, Kirkwood JM, Kluger HM, Lee SJ, Schuchter LM, Flaherty KT, Nathanson KL. Correlation of somatic mutations and clinical outcome in melanoma patients treated with Carboplatin, Paclitaxel, and sorafenib. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 20: 3328-37. PMID 24714776 DOI: 10.1158/1078-0432.Ccr-14-0093 |
0.311 |
|
| 2014 |
Osorio A, Milne RL, Kuchenbaecker K, Vaclová T, Pita G, Alonso R, Peterlongo P, Blanco I, de la Hoya M, Duran M, DÃez O, Ramón Y Cajal T, Konstantopoulou I, MartÃnez-Bouzas C, Andrés Conejero R, ... ... Nathanson K, et al. DNA glycosylases involved in base excision repair may be associated with cancer risk in BRCA1 and BRCA2 mutation carriers. Plos Genetics. 10: e1004256. PMID 24698998 DOI: 10.1371/Journal.Pgen.1004256 |
0.501 |
|
| 2014 |
Couch FJ, Nathanson KL, Offit K. Two decades after BRCA: setting paradigms in personalized cancer care and prevention. Science (New York, N.Y.). 343: 1466-70. PMID 24675953 DOI: 10.1126/Science.1251827 |
0.5 |
|
| 2014 |
Haas NB, Nathanson KL. Hereditary kidney cancer syndromes. Advances in Chronic Kidney Disease. 21: 81-90. PMID 24359990 DOI: 10.1053/J.Ackd.2013.10.001 |
0.447 |
|
| 2014 |
Daber RD, Langer CJ, Luger SM, Schuchter LM, Gilliland DG, Roth D, Carroll M, Nathanson KL, Morrissette JJ. A look back: Results from 1 year of routine clinical testing of both hematologic and solid tumors using two targeted next-generation sequencing (NGS) panels. Journal of Clinical Oncology. 32. DOI: 10.1200/Jco.2014.32.15_Suppl.E22099 |
0.41 |
|
| 2014 |
Maxwell KN, Wubbenhorst B, Garman B, D'Andrea KP, Rathbun K, Long J, Powers J, Stopfer J, Bradbury AR, DeMichele A, Domchek SM, Nathanson KL. Prevalence of mutations in a panel of breast cancer susceptibility genes in patients with early onset breast cancer. Journal of Clinical Oncology. 32: 1510-1510. DOI: 10.1200/Jco.2014.32.15_Suppl.1510 |
0.487 |
|
| 2014 |
Zheng Y, Huo D, Ogundiran TO, Falusi AG, Ojengbede O, Adebamowo C, Blot WJ, Zheng W, Cai Q, Signorello LB, Nathanson KL, Domchek SM, Rebbeck TR, Simon MS, Hennis AJM, et al. Abstract B11: Replication of previously identified breast cancer susceptibility loci in a breast cancer case-control study on women of African ancestry Cancer Epidemiology, Biomarkers & Prevention. 23. DOI: 10.1158/1538-7755.Disp13-B11 |
0.445 |
|
| 2014 |
Wilson MA, Zhao F, Khare S, Letrero R, D'Andrea K, Rimm DL, Kirkwood JM, Kluger HM, Lee SJ, Schuchter LM, Flaherty KT, Nathanson KL. Abstract 933: Copy number changes are associated withBRAFandNRASmutations and response to treatment with carboplatin, paclitaxel and sorafenib Cancer Research. 74: 933-933. DOI: 10.1158/1538-7445.Am2014-933 |
0.432 |
|
| 2014 |
Schrader KA, Maxwell KN, Vijai J, Hart S, Thomas T, Wubbenhorst B, Guidugli L, Klein R, Corines M, Zhang L, Neuhausen S, Weitzel J, Gupta N, Norton L, Hudis C, ... ... Nathanson K, et al. Abstract 3282: Determination of cancer susceptibility in probands with breast and ovarian cancer Cancer Research. 74: 3282-3282. DOI: 10.1158/1538-7445.Am2014-3282 |
0.485 |
|
| 2014 |
Vijai J, Hart S, Thomas T, Wubbenhorst B, Guidugli L, Schrader K, Maxwell K, Jacobs L, Villano D, Klein R, Lipkin S, Neuhausen S, Weitzel J, Altshuler D, Couch F, ... ... Nathanson K, et al. Abstract 2378: Harmonization of next generation sequencing data within consortia for gene discovery in familial breast cancer Cancer Research. 74: 2378-2378. DOI: 10.1158/1538-7445.Am2014-2378 |
0.408 |
|
| 2014 |
Maxwell KN, Guidugli L, Schrader K, Hart S, Joseph V, Thomas T, Wang X, Wubbenhorst B, Klein R, Domchek SM, Szabo C, Neuhausen S, Weitzel J, Nathanson KL, Offit K, et al. Abstract 1291: High and moderate penetrance germline mutations in a number of genes are responsible for a small proportion of familial breast cancer risk in BRCAx families Cancer Research. 74: 1291-1291. DOI: 10.1158/1538-7445.Am2014-1291 |
0.503 |
|
| 2014 |
Krepler C, Sproesser K, Brafford P, Xiao M, Beqiri M, Xu W, Nathanson K, Wargo J, Flaherty K, Morton DL, Hoon DS, Ryan R, Guarino M, Petrelli NJ, Elder D, et al. Abstract 1182: Patient derived xenograft (PDX) of human melanoma to predict clinical responses Cancer Research. 74: 1182-1182. DOI: 10.1158/1538-7445.Am2014-1182 |
0.374 |
|
| 2014 |
Yang R, Lee K, Graves HL, Nathanson K, Domchek S, Kelz RR, Zhang P, Czerniecki BJ. Receptor Tyrosine Kinase Expression in BRCA Mutation Carriers: An Opportunity for Prevention of Invasive Breast Cancer Journal of the American College of Surgeons. 219. DOI: 10.1016/J.Jamcollsurg.2014.07.299 |
0.415 |
|
| 2013 |
Maxwell KN, Nathanson KL. Common breast cancer risk variants in the post-COGS era: a comprehensive review. Breast Cancer Research : Bcr. 15: 212. PMID 24359602 DOI: 10.1186/Bcr3591 |
0.52 |
|
| 2013 |
Villanueva J, Infante JR, Krepler C, Reyes-Uribe P, Samanta M, Chen HY, Li B, Swoboda RK, Wilson M, Vultur A, Fukunaba-Kalabis M, Wubbenhorst B, Chen TY, Liu Q, Sproesser K, ... ... Nathanson KL, et al. Concurrent MEK2 mutation and BRAF amplification confer resistance to BRAF and MEK inhibitors in melanoma. Cell Reports. 4: 1090-9. PMID 24055054 DOI: 10.1016/J.Celrep.2013.08.023 |
0.341 |
|
| 2013 |
Lee EK, Lian Z, D'Andrea K, Letrero R, Sheng W, Liu S, Diehl JN, Pytel D, Barbash O, Schuchter L, Amaravaradi R, Xu X, Herlyn M, Nathanson KL, Diehl JA. The FBXO4 tumor suppressor functions as a barrier to BRAFV600E-dependent metastatic melanoma. Molecular and Cellular Biology. 33: 4422-33. PMID 24019069 DOI: 10.1128/Mcb.00706-13 |
0.315 |
|
| 2013 |
Vonderheide RH, Nathanson KL. Immunotherapy at large: the road to personalized cancer vaccines. Nature Medicine. 19: 1098-100. PMID 24013748 DOI: 10.1038/Nm.3317 |
0.375 |
|
| 2013 |
Shah S, Schrader KA, Waanders E, Timms AE, Vijai J, Miething C, Wechsler J, Yang J, Hayes J, Klein RJ, Zhang J, Wei L, Wu G, Rusch M, Nagahawatte P, ... ... Nathanson KL, et al. A recurrent germline PAX5 mutation confers susceptibility to pre-B cell acute lymphoblastic leukemia. Nature Genetics. 45: 1226-31. PMID 24013638 DOI: 10.1038/Ng.2754 |
0.354 |
|
| 2013 |
Keefe SM, Nathanson KL, Rathmell WK. The molecular biology of renal cell carcinoma. Seminars in Oncology. 40: 421-8. PMID 23972705 DOI: 10.1053/J.Seminoncol.2013.05.006 |
0.391 |
|
| 2013 |
Nathanson KL, Martin AM, Wubbenhorst B, Greshock J, Letrero R, D'Andrea K, O'Day S, Infante JR, Falchook GS, Arkenau HT, Millward M, Brown MP, Pavlick A, Davies MA, Ma B, et al. Tumor genetic analyses of patients with metastatic melanoma treated with the BRAF inhibitor dabrafenib (GSK2118436). Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 19: 4868-78. PMID 23833299 DOI: 10.1158/1078-0432.Ccr-13-0827 |
0.392 |
|
| 2013 |
Southey MC, Park DJ, Nguyen-Dumont T, Campbell I, Thompson E, Trainer AH, Chenevix-Trench G, Simard J, Dumont M, Soucy P, Thomassen M, Jønson L, Pedersen IS, Hansen TV, ... ... Nathanson K, et al. COMPLEXO: identifying the missing heritability of breast cancer via next generation collaboration. Breast Cancer Research : Bcr. 15: 402. PMID 23809231 DOI: 10.1186/Bcr3434 |
0.485 |
|
| 2013 |
Chung CC, Kanetsky PA, Wang Z, Hildebrandt MA, Koster R, Skotheim RI, Kratz CP, Turnbull C, Cortessis VK, Bakken AC, Bishop DT, Cook MB, Erickson RL, Fosså SD, Jacobs KB, ... ... Nathanson KL, et al. Meta-analysis identifies four new loci associated with testicular germ cell tumor. Nature Genetics. 45: 680-5. PMID 23666239 DOI: 10.1038/Ng.2634 |
0.345 |
|
| 2013 |
Monda KL, Chen GK, Taylor KC, Palmer C, Edwards TL, Lange LA, Ng MC, Adeyemo AA, Allison MA, Bielak LF, Chen G, Graff M, Irvin MR, Rhie SK, Li G, ... ... Nathanson KL, et al. A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry. Nature Genetics. 45: 690-6. PMID 23583978 DOI: 10.1038/Ng.2608 |
0.308 |
|
| 2013 |
Sabbaghian N, Bahubeshi A, Shuen AY, Kanetsky PA, Tischkowitz MD, Nathanson KL, Foulkes WD. Germ-line DICER1 mutations do not make a major contribution to the etiology of familial testicular germ cell tumours. Bmc Research Notes. 6: 127. PMID 23547758 DOI: 10.1186/1756-0500-6-127 |
0.383 |
|
| 2013 |
Couch FJ, Wang X, McGuffog L, Lee A, Olswold C, Kuchenbaecker KB, Soucy P, Fredericksen Z, Barrowdale D, Dennis J, Gaudet MM, Dicks E, Kosel M, Healey S, Sinilnikova OM, ... ... Nathanson KL, et al. Genome-wide association study in BRCA1 mutation carriers identifies novel loci associated with breast and ovarian cancer risk. Plos Genetics. 9: e1003212. PMID 23544013 DOI: 10.1371/Journal.Pgen.1003212 |
0.476 |
|
| 2013 |
Gaudet MM, Kuchenbaecker KB, Vijai J, Klein RJ, Kirchhoff T, McGuffog L, Barrowdale D, Dunning AM, Lee A, Dennis J, Healey S, Dicks E, Soucy P, Sinilnikova OM, Pankratz VS, ... ... Nathanson KL, et al. Identification of a BRCA2-specific modifier locus at 6p24 related to breast cancer risk. Plos Genetics. 9: e1003173. PMID 23544012 DOI: 10.1371/Journal.Pgen.1003173 |
0.524 |
|
| 2013 |
Bojesen SE, Pooley KA, Johnatty SE, Beesley J, Michailidou K, Tyrer JP, Edwards SL, Pickett HA, Shen HC, Smart CE, Hillman KM, Mai PL, Lawrenson K, Stutz MD, Lu Y, ... ... Nathanson KL, et al. Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer. Nature Genetics. 45: 371-84, 384e1-2. PMID 23535731 DOI: 10.1038/Ng.2566 |
0.439 |
|
| 2013 |
Fishbein L, Merrill S, Fraker DL, Cohen DL, Nathanson KL. Inherited mutations in pheochromocytoma and paraganglioma: why all patients should be offered genetic testing. Annals of Surgical Oncology. 20: 1444-50. PMID 23512077 DOI: 10.1245/S10434-013-2942-5 |
0.373 |
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| 2013 |
Zheng Y, Ogundiran TO, Falusi AG, Nathanson KL, John EM, Hennis AJ, Ambs S, Domchek SM, Rebbeck TR, Simon MS, Nemesure B, Wu SY, Leske MC, Odetunde A, Niu Q, et al. Fine mapping of breast cancer genome-wide association studies loci in women of African ancestry identifies novel susceptibility markers. Carcinogenesis. 34: 1520-8. PMID 23475944 DOI: 10.1093/Carcin/Bgt090 |
0.46 |
|
| 2013 |
Schumacher FR, Wang Z, Skotheim RI, Koster R, Chung CC, Hildebrandt MA, Kratz CP, Bakken AC, Bishop DT, Cook MB, Erickson RL, Fosså SD, Greene MH, Jacobs KB, Kanetsky PA, ... ... Nathanson KL, et al. Testicular germ cell tumor susceptibility associated with the UCK2 locus on chromosome 1q23. Human Molecular Genetics. 22: 2748-53. PMID 23462292 DOI: 10.1093/Hmg/Ddt109 |
0.371 |
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| 2013 |
Domchek SM, Tang J, Stopfer J, Lilli DR, Hamel N, Tischkowitz M, Monteiro AN, Messick TE, Powers J, Yonker A, Couch FJ, Goldgar DE, Davidson HR, Nathanson KL, Foulkes WD, et al. Biallelic deleterious BRCA1 mutations in a woman with early-onset ovarian cancer. Cancer Discovery. 3: 399-405. PMID 23269703 DOI: 10.1158/2159-8290.Cd-12-0421 |
0.495 |
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| 2013 |
Domchek SM, Jhaveri K, Patil S, Stopfer JE, Hudis C, Powers J, Stadler Z, Goldstein L, Kauff N, Khasraw M, Offit K, Nathanson KL, Robson M. Risk of metachronous breast cancer after BRCA mutation-associated ovarian cancer. Cancer. 119: 1344-8. PMID 23165893 DOI: 10.1002/Cncr.27842 |
0.457 |
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| 2013 |
Guidugli L, Pankratz VS, Singh N, Thompson J, Erding CA, Engel C, Schmutzler R, Domchek S, Nathanson K, Radice P, Singer C, Tonin PN, Lindor NM, Goldgar DE, Couch FJ. A classification model for BRCA2 DNA binding domain missense variants based on homology-directed repair activity. Cancer Research. 73: 265-75. PMID 23108138 DOI: 10.1158/0008-5472.Can-12-2081 |
0.434 |
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| 2013 |
Chen F, Chen GK, Stram DO, Millikan RC, Ambrosone CB, John EM, Bernstein L, Zheng W, Palmer JR, Hu JJ, Rebbeck TR, Ziegler RG, Nyante S, Bandera EV, Ingles SA, ... ... Nathanson KL, et al. A genome-wide association study of breast cancer in women of African ancestry. Human Genetics. 132: 39-48. PMID 22923054 DOI: 10.1007/S00439-012-1214-Y |
0.434 |
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| 2013 |
Satpute SR, Koster R, Nathanson KL, Vaughn DJ, Albany C, Einhorn LH, Hanna NH. Retrospective, correlative study of BRAF mutation V600E in testicular cancer patients. Journal of Clinical Oncology. 31. DOI: 10.1200/Jco.2013.31.15_Suppl.E15584 |
0.401 |
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| 2013 |
Chu EY, Wilson M, Sobanko J, Miller C, Suh E, Xu W, Letrero R, Elenitsas R, Karakousis G, Xu Xw, Elder D, Amaravadi RK, Schuchter LM, Nathanson KL. NRAS and BRAF mutations in atypical melanocytic lesions arising in melanoma patients treated with vemurafenib. Journal of Clinical Oncology. 31: 9017-9017. DOI: 10.1200/Jco.2013.31.15_Suppl.9017 |
0.343 |
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| 2013 |
Maxwell KN, De Sloover D, Emery L, Wubbenhorst B, D'Andrea KP, Long J, Mueller R, Powers J, Stopfer J, Feldman MD, Domchek SM, Daber R, Nathanson KL. The mutational spectrum of breast and ovarian tumors from BRCA1 and BRCA2 mutation carriers. Journal of Clinical Oncology. 31: 1510-1510. DOI: 10.1200/Jco.2013.31.15_Suppl.1510 |
0.468 |
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| 2013 |
Maxwell KN, Wubbenhorst B, Letrero R, D'Andrea K, Powers J, Stopfer JE, Domchek SM, Nathanson KL. Abstract 2280: Targeted massively parallel sequencing identifies a limited number of clinically actionable variants in women with early onset breast cancer. Cancer Research. 73: 2280-2280. DOI: 10.1158/1538-7445.Am2013-2280 |
0.508 |
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| 2012 |
Fung C, Vaughn DJ, Mitra N, Ciosek SL, Vardhanabhuti S, Nathanson KL, Kanetsky PA. Association of GSTP1, COMT, and TPMT with testicular cancer (TC) treatment outcome after cisplatin-based chemotherapy (CBCT). Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 30: 344. PMID 27968008 DOI: 10.1200/Jco.2012.30.5_Suppl.344 |
0.311 |
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| 2012 |
Fung C, Vaughn DJ, Mitra N, Ciosek SL, Vardhanabhuti S, Nathanson KL, Kanetsky PA. Chemotherapy refractory testicular germ cell tumor is associated with a variant in Armadillo Repeat gene deleted in Velco-Cardio-Facial syndrome (ARVCF). Frontiers in Endocrinology. 3: 163. PMID 23248619 DOI: 10.3389/Fendo.2012.00163 |
0.362 |
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| 2012 |
Stevens KN, Wang X, Fredericksen Z, Pankratz VS, Greene MH, Andrulis IL, Thomassen M, Caligo M, Nathanson KL, Jakubowska A, Osorio A, Hamann U, Godwin AK, Stoppa-Lyonnet D, et al. Evaluation of chromosome 6p22 as a breast cancer risk modifier locus in a follow-up study of BRCA2 mutation carriers. Breast Cancer Research and Treatment. 136: 295-302. PMID 23011509 DOI: 10.1007/S10549-012-2255-6 |
0.516 |
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| 2012 |
Kirchhoff T, Gaudet MM, Antoniou AC, McGuffog L, Humphreys MK, Dunning AM, Bojesen SE, Nordestgaard BG, Flyger H, Kang D, Yoo KY, Noh DY, Ahn SH, Dork T, Schürmann P, ... ... Nathanson KL, et al. Breast cancer risk and 6q22.33: combined results from Breast Cancer Association Consortium and Consortium of Investigators on Modifiers of BRCA1/2. Plos One. 7: e35706. PMID 22768030 DOI: 10.1371/journal.pone.0035706 |
0.375 |
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| 2012 |
Ding YC, McGuffog L, Healey S, Friedman E, Laitman Y, Paluch-Shimon S, Kaufman B, Liljegren A, Lindblom A, Olsson H, Kristoffersson U, Stenmark-Askmalm M, Melin B, Domchek SM, ... Nathanson KL, et al. A nonsynonymous polymorphism in IRS1 modifies risk of developing breast and ovarian cancers in BRCA1 and ovarian cancer in BRCA2 mutation carriers. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 21: 1362-70. PMID 22729394 DOI: 10.1158/1055-9965.Epi-12-0229 |
0.495 |
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| 2012 |
Jakubowska A, Rozkrut D, Antoniou A, Hamann U, Scott RJ, McGuffog L, Healy S, Sinilnikova OM, Rennert G, Lejbkowicz F, Flugelman A, Andrulis IL, Glendon G, Ozcelik H, ... ... Nathanson KL, et al. Association of PHB 1630 C>T and MTHFR 677 C>T polymorphisms with breast and ovarian cancer risk in BRCA1/2 mutation carriers: results from a multicenter study. British Journal of Cancer. 106: 2016-24. PMID 22669161 DOI: 10.1038/Bjc.2012.160 |
0.493 |
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| 2012 |
Wilson MA, Nathanson KL. Molecular testing in melanoma. Cancer Journal (Sudbury, Mass.). 18: 117-23. PMID 22453011 DOI: 10.1097/Ppo.0B013E31824F11Bf |
0.412 |
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| 2012 |
Fishbein L, Nathanson KL. Pheochromocytoma and paraganglioma: understanding the complexities of the genetic background. Cancer Genetics. 205: 1-11. PMID 22429592 DOI: 10.1016/J.Cancergen.2012.01.009 |
0.432 |
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| 2012 |
Huo D, Zheng Y, Ogundiran TO, Adebamowo C, Nathanson KL, Domchek SM, Rebbeck TR, Simon MS, John EM, Hennis A, Nemesure B, Wu SY, Leske MC, Ambs S, Niu Q, et al. Evaluation of 19 susceptibility loci of breast cancer in women of African ancestry. Carcinogenesis. 33: 835-40. PMID 22357627 DOI: 10.1093/Carcin/Bgs093 |
0.406 |
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| 2012 |
Couch FJ, Gaudet MM, Antoniou AC, Ramus SJ, Kuchenbaecker KB, Soucy P, Beesley J, Chen X, Wang X, Kirchhoff T, McGuffog L, Barrowdale D, Lee A, Healey S, Sinilnikova OM, ... ... Nathanson KL, et al. Common variants at the 19p13.1 and ZNF365 loci are associated with ER subtypes of breast cancer and ovarian cancer risk in BRCA1 and BRCA2 mutation carriers. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 21: 645-57. PMID 22351618 DOI: 10.1158/1055-9965.Epi-11-0888 |
0.514 |
|
| 2012 |
Antoniou AC, Kuchenbaecker KB, Soucy P, Beesley J, Chen X, McGuffog L, Lee A, Barrowdale D, Healey S, Sinilnikova OM, Caligo MA, Loman N, Harbst K, Lindblom A, Arver B, ... ... Nathanson K, et al. Common variants at 12p11, 12q24, 9p21, 9q31.2 and in ZNF365 are associated with breast cancer risk for BRCA1 and/or BRCA2 mutation carriers. Breast Cancer Research : Bcr. 14: R33. PMID 22348646 DOI: 10.1186/Bcr3121 |
0.444 |
|
| 2012 |
Ramus SJ, Antoniou AC, Kuchenbaecker KB, Soucy P, Beesley J, Chen X, McGuffog L, Sinilnikova OM, Healey S, Barrowdale D, Lee A, Thomassen M, Gerdes AM, Kruse TA, Jensen UB, ... ... Nathanson KL, et al. Ovarian cancer susceptibility alleles and risk of ovarian cancer in BRCA1 and BRCA2 mutation carriers. Human Mutation. 33: 690-702. PMID 22253144 DOI: 10.1002/Humu.22025 |
0.444 |
|
| 2012 |
Hou N, Zheng Y, Gamazon ER, Ogundiran TO, Adebamowo C, Nathanson KL, Domchek SM, Rebbeck TR, Simon MS, John EM, Hennis A, Nemesure B, Wu SY, Leske MC, Ambs S, et al. Genetic susceptibility to type 2 diabetes and breast cancer risk in women of European and African ancestry. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 21: 552-6. PMID 22237986 DOI: 10.1158/1055-9965.Epi-11-0979 |
0.443 |
|
| 2012 |
Laitman Y, Kuchenbaecker KB, Rantala J, Hogervorst F, Peock S, Godwin AK, Arason A, Kirchhoff T, Offit K, Isaacs C, Schmutzler RK, Wappenschmidt B, Nevanlinna H, Chen X, Chenevix-Trench G, ... ... Nathanson KL, et al. The KL-VS sequence variant of Klotho and cancer risk in BRCA1 and BRCA2 mutation carriers. Breast Cancer Research and Treatment. 132: 1119-26. PMID 22212556 DOI: 10.1007/S10549-011-1938-8 |
0.513 |
|
| 2012 |
Mavaddat N, Barrowdale D, Andrulis IL, Domchek SM, Eccles D, Nevanlinna H, Ramus SJ, Spurdle A, Robson M, Sherman M, Mulligan AM, Couch FJ, Engel C, McGuffog L, Healey S, ... ... Nathanson K, et al. Pathology of breast and ovarian cancers among BRCA1 and BRCA2 mutation carriers: results from the Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA). Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 21: 134-47. PMID 22144499 DOI: 10.1158/1055-9965.Epi-11-0775 |
0.468 |
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| 2012 |
Zheng Y, Ogundiran TO, Adebamowo C, Nathanson KL, Domchek SM, Rebbeck TR, Simon MS, John EM, Hennis A, Nemesure B, Wu SY, Leske MC, Ambs S, Niu Q, Zhang J, et al. Lack of association between common single nucleotide polymorphisms in the TERT-CLPTM1L locus and breast cancer in women of African ancestry. Breast Cancer Research and Treatment. 132: 341-5. PMID 22134622 DOI: 10.1007/S10549-011-1890-7 |
0.446 |
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| 2012 |
Dondeti VR, Wubbenhorst B, Lal P, Gordan JD, D'Andrea K, Attiyeh EF, Simon MC, Nathanson KL. Integrative genomic analyses of sporadic clear cell renal cell carcinoma define disease subtypes and potential new therapeutic targets. Cancer Research. 72: 112-21. PMID 22094876 DOI: 10.1158/0008-5472.CAN-11-1698 |
0.775 |
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| 2012 |
Spurdle AB, Healey S, Devereau A, Hogervorst FB, Monteiro AN, Nathanson KL, Radice P, Stoppa-Lyonnet D, Tavtigian S, Wappenschmidt B, Couch FJ, Goldgar DE. ENIGMA--evidence-based network for the interpretation of germline mutant alleles: an international initiative to evaluate risk and clinical significance associated with sequence variation in BRCA1 and BRCA2 genes. Human Mutation. 33: 2-7. PMID 21990146 DOI: 10.1002/Humu.21628 |
0.431 |
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| 2012 |
Cohen JV, Chiel L, Boghossian L, Jones M, Stopfer JE, Powers J, Rebbeck TR, Nathanson KL, Domchek SM. Non-cancer endpoints in BRCA1/2 carriers after risk-reducing salpingo-oophorectomy. Familial Cancer. 11: 69-75. PMID 21898151 DOI: 10.1007/S10689-011-9480-8 |
0.391 |
|
| 2012 |
Kirchhoff T, Gaudet MM, Antoniou AC, McGuffog L, Humphreys MK, Dunning AM, Bojesen SE, Nordestgaard BG, Flyger H, Kang D, Yoo K, Noh D, Ahn S, Dörk T, Schürmann P, ... ... Nathanson KL, et al. SNP rs2180341 per-allele hazard ratios (HRs) and 95% confidence intervals (CIs) among Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA) in A. BRCA1 mutation carriers B. BRCA2 mutation carriers. Plos One. DOI: 10.1371/Journal.Pone.0035706.G002 |
0.368 |
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| 2012 |
Shah PD, Garber JE, Stopfer J, Powers J, Nathanson KL, Domchek SM. Sensitivity of clinical BRCA1 testing compared with linkage analysis. Journal of Clinical Oncology. 30: 1506-1506. DOI: 10.1200/Jco.2012.30.15_Suppl.1506 |
0.424 |
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| 2012 |
Wilson MA, Zhao F, Letrero R, D'Andrea K, Rimm D, Kirkwood J, Kluger H, Lee S, Flaherty K, Nathanson K. Abstract 5557: Mutation analysis of melanoma tumor samples from ECOG 2603 clinical trial Cancer Research. 72: 5557-5557. DOI: 10.1158/1538-7445.Am2012-5557 |
0.405 |
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| 2012 |
Koster R, Kanetsky PA, Mitra N, Vardhanabhuti S, Ciosek SL, Letrero R, D'Andrea K, Doody DR, Chen C, Vaughn DJ, Schwartz SM, Nathanson KL. Abstract 2622: SNP markers in theFGF9andMAP3K1region associate with testicular germ cell tumor susceptibility Cancer Research. 72: 2622-2622. DOI: 10.1158/1538-7445.Am2012-2622 |
0.377 |
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| 2012 |
Zheng Y, Ogundiran TO, Adebamowo C, Nathanson KL, Domchek SM, Rebbeck TR, Simon MS, John EM, Hennis A, Nemesure B, Wu S, Leske MC, Ambs S, Niu Q, Zhang J, et al. Abstract 2606: Absence of association between common genetic polymorphisms in the TERT-CLPTM1L locus and breast cancer risk in women of African descent Cancer Research. 72: 2606-2606. DOI: 10.1158/1538-7445.Am2012-2606 |
0.447 |
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| 2012 |
Krepler C, Herlyn M, Villanueva J, Samatar A, Chen Y, Halloran M, Samanta M, He X, Vultur A, Wubbenhorst B, Nathanson K. Abstract B12: PTEN modulates sensitivity to a novel ERK inhibitor in BRAFV600E-mutant melanomas Clinical Cancer Research. 18: B12-B12. DOI: 10.1158/1078-0432.Mechres-B12 |
0.322 |
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| 2012 |
Yang RL, Graves HL, Zhang PJ, Nathanson K, Domchek SM, Czerniecki BJ, Kelz RR. Characteristics of ductal carcinoma in situ found in BRCA1 and BRCA2 mutation carriers Journal of the American College of Surgeons. 215. DOI: 10.1016/J.Jamcollsurg.2012.06.327 |
0.37 |
|
| 2011 |
Nathanson KL, Martin A, Letrero R, D'Andrea KP, O'Day S, Infante JR, Falchook GS, Millward M, Curtis CM, Ma B, Gagnon RC, Lebowitz PF, Long GV, Kefford RF. Tumor genetic analyses of patients with metastatic melanoma treated with the BRAF inhibitor GSK2118436 (GSK436). Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 29: 8501. PMID 28021152 DOI: 10.1200/Jco.2011.29.15_Suppl.8501 |
0.335 |
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| 2011 |
Fung C, Vaughn DJ, Mitra N, Vardhanabhuti S, Ciosek SL, Nathanson KL, Kanetsky PA. Association of COMT and TPMT with treatment failure (TF), neuropathy (NTOX), and ototoxicity (OTOX) in patients with testicular cancer (TC) after cisplatin-based chemotherapy (CBCT). Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 29: e15076. PMID 28020425 DOI: 10.1200/Jco.2011.29.15_Suppl.E15076 |
0.351 |
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| 2011 |
Maxwell CA, Benítez J, Gómez-Baldó L, Osorio A, Bonifaci N, Fernández-Ramires R, Costes SV, Guinó E, Chen H, Evans GJ, Mohan P, Català I, Petit A, Aguilar H, Villanueva A, ... ... Nathanson KL, et al. Interplay between BRCA1 and RHAMM regulates epithelial apicobasal polarization and may influence risk of breast cancer. Plos Biology. 9: e1001199. PMID 22110403 DOI: 10.1371/Journal.Pbio.1001199 |
0.475 |
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| 2011 |
Mulligan AM, Couch FJ, Barrowdale D, Domchek SM, Eccles D, Nevanlinna H, Ramus SJ, Robson M, Sherman M, Spurdle AB, Wappenschmidt B, Lee A, McGuffog L, Healey S, Sinilnikova OM, ... ... Nathanson KL, et al. Common breast cancer susceptibility alleles are associated with tumour subtypes in BRCA1 and BRCA2 mutation carriers: results from the Consortium of Investigators of Modifiers of BRCA1/2. Breast Cancer Research : Bcr. 13: R110. PMID 22053997 DOI: 10.1186/Bcr3052 |
0.488 |
|
| 2011 |
Cox DG, Simard J, Sinnett D, Hamdi Y, Soucy P, Ouimet M, Barjhoux L, Verny-Pierre C, McGuffog L, Healey S, Szabo C, Greene MH, Mai PL, Andrulis IL, ... ... Nathanson KL, et al. Common variants of the BRCA1 wild-type allele modify the risk of breast cancer in BRCA1 mutation carriers. Human Molecular Genetics. 20: 4732-47. PMID 21890493 DOI: 10.1093/Hmg/Ddr388 |
0.509 |
|
| 2011 |
Rebbeck TR, Mitra N, Domchek SM, Wan F, Friebel TM, Tran TV, Singer CF, Tea MK, Blum JL, Tung N, Olopade OI, Weitzel JN, Lynch HT, Snyder CL, Garber JE, ... ... Nathanson KL, et al. Modification of BRCA1-Associated Breast and Ovarian Cancer Risk by BRCA1-Interacting Genes. Cancer Research. 71: 5792-805. PMID 21799032 DOI: 10.1158/0008-5472.Can-11-0773 |
0.484 |
|
| 2011 |
Neuhausen SL, Brummel S, Ding YC, Steele L, Nathanson KL, Domchek S, Rebbeck TR, Singer CF, Pfeiler G, Lynch HT, Garber JE, Couch F, Weitzel JN, Godwin A, Narod SA, et al. Genetic variation in IGF2 and HTRA1 and breast cancer risk among BRCA1 and BRCA2 carriers. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 20: 1690-702. PMID 21708937 DOI: 10.1158/1055-9965.Epi-10-1336 |
0.46 |
|
| 2011 |
Im KM, Kirchhoff T, Wang X, Green T, Chow CY, Vijai J, Korn J, Gaudet MM, Fredericksen Z, Shane Pankratz V, Guiducci C, Crenshaw A, McGuffog L, Kartsonaki C, Morrison J, ... ... Nathanson KL, et al. Haplotype structure in Ashkenazi Jewish BRCA1 and BRCA2 mutation carriers. Human Genetics. 130: 685-99. PMID 21597964 DOI: 10.1007/S00439-011-1003-Z |
0.431 |
|
| 2011 |
Antoniou AC, Kartsonaki C, Sinilnikova OM, Soucy P, McGuffog L, Healey S, Lee A, Peterlongo P, Manoukian S, Peissel B, Zaffaroni D, Cattaneo E, Barile M, Pensotti V, Pasini B, ... ... Nathanson KL, et al. Common alleles at 6q25.1 and 1p11.2 are associated with breast cancer risk for BRCA1 and BRCA2 mutation carriers. Human Molecular Genetics. 20: 3304-21. PMID 21593217 DOI: 10.1093/Hmg/Ddr226 |
0.491 |
|
| 2011 |
Huang J, Zhang L, Greshock J, Colligon TA, Wang Y, Ward R, Katsaros D, Lassus H, Butzow R, Godwin AK, Testa JR, Nathanson KL, Gimotty PA, Coukos G, Weber BL, et al. Frequent genetic abnormalities of the PI3K/AKT pathway in primary ovarian cancer predict patient outcome. Genes, Chromosomes & Cancer. 50: 606-18. PMID 21563232 DOI: 10.1002/Gcc.20883 |
0.454 |
|
| 2011 |
Kanetsky PA, Mitra N, Vardhanabhuti S, Vaughn DJ, Li M, Ciosek SL, Letrero R, D'Andrea K, Vaddi M, Doody DR, Weaver J, Chen C, Starr JR, HÃ¥konarson H, Rader DJ, ... ... Nathanson KL, et al. A second independent locus within DMRT1 is associated with testicular germ cell tumor susceptibility. Human Molecular Genetics. 20: 3109-17. PMID 21551455 DOI: 10.1093/Hmg/Ddr207 |
0.346 |
|
| 2011 |
Martrat G, Maxwell CM, Tominaga E, Porta-de-la-Riva M, Bonifaci N, Gómez-Baldó L, Bogliolo M, Lázaro C, Blanco I, Brunet J, Aguilar H, Fernández-RodrÃguez J, Seal S, Renwick A, Rahman N, ... ... Nathanson KL, et al. Exploring the link between MORF4L1 and risk of breast cancer. Breast Cancer Research : Bcr. 13: R40. PMID 21466675 DOI: 10.1186/Bcr2862 |
0.489 |
|
| 2011 |
Osorio A, Milne RL, Alonso R, Pita G, Peterlongo P, Teulé A, Nathanson KL, Domchek SM, Rebbeck T, Lasa A, Konstantopoulou I, Hogervorst FB, Verhoef S, van Dooren MF, Jager A, et al. Evaluation of the XRCC1 gene as a phenotypic modifier in BRCA1/2 mutation carriers. Results from the consortium of investigators of modifiers of BRCA1/BRCA2. British Journal of Cancer. 104: 1356-61. PMID 21427728 DOI: 10.1038/Bjc.2011.91 |
0.417 |
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| 2011 |
Benhammou JN, Vocke CD, Santani A, Schmidt LS, Baba M, Seyama K, Wu X, Korolevich S, Nathanson KL, Stolle CA, Linehan WM. Identification of intragenic deletions and duplication in the FLCN gene in Birt-Hogg-Dubé syndrome. Genes, Chromosomes & Cancer. 50: 466-77. PMID 21412933 DOI: 10.1002/Gcc.20872 |
0.382 |
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| 2011 |
Spurdle AB, Marquart L, McGuffog L, Healey S, Sinilnikova O, Wan F, Chen X, Beesley J, Singer CF, Dressler AC, Gschwantler-Kaulich D, Blum JL, Tung N, Weitzel J, Lynch H, ... ... Nathanson K, et al. Common genetic variation at BARD1 is not associated with breast cancer risk in BRCA1 or BRCA2 mutation carriers. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 20: 1032-8. PMID 21393566 DOI: 10.1158/1055-9965.Epi-10-0909 |
0.493 |
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| 2011 |
Pharoah PD, Palmieri RT, Ramus SJ, Gayther SA, Andrulis IL, Anton-Culver H, Antonenkova N, Antoniou AC, Goldgar D, Beattie MS, Beckmann MW, Birrer MJ, Bogdanova N, Bolton KL, ... ... Nathanson KL, et al. The role of KRAS rs61764370 in invasive epithelial ovarian cancer: implications for clinical testing. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 3742-50. PMID 21385923 DOI: 10.1158/1078-0432.Ccr-10-3405 |
0.417 |
|
| 2011 |
Hofstatter EW, Domchek SM, Miron A, Garber J, Wang M, Componeschi K, Boghossian L, Miron PL, Nathanson KL, Tung N. PALB2 mutations in familial breast and pancreatic cancer. Familial Cancer. 10: 225-31. PMID 21365267 DOI: 10.1007/S10689-011-9426-1 |
0.471 |
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| 2011 |
Ma XH, Piao S, Wang D, McAfee QW, Nathanson KL, Lum JJ, Li LZ, Amaravadi RK. Measurements of tumor cell autophagy predict invasiveness, resistance to chemotherapy, and survival in melanoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 3478-89. PMID 21325076 DOI: 10.1158/1078-0432.Ccr-10-2372 |
0.322 |
|
| 2011 |
Ramus SJ, Kartsonaki C, Gayther SA, Pharoah PD, Sinilnikova OM, Beesley J, Chen X, McGuffog L, Healey S, Couch FJ, Wang X, Fredericksen Z, Peterlongo P, Manoukian S, Peissel B, ... ... Nathanson KL, et al. Genetic variation at 9p22.2 and ovarian cancer risk for BRCA1 and BRCA2 mutation carriers. Journal of the National Cancer Institute. 103: 105-16. PMID 21169536 DOI: 10.1093/Jnci/Djq494 |
0.514 |
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| 2011 |
Nathanson KL, Domchek SM. Therapeutic Approaches for Women Predisposed to Breast Cancer Annual Review of Medicine. 62: 295-306. PMID 21034216 DOI: 10.1146/Annurev-Med-010910-110221 |
0.482 |
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| 2011 |
Huo D, Zheng Y, Ogundiran TO, Adebamowo C, Nathanson KL, Domchek SM, Rebbeck TR, John EM, Hennis A, Nemesure B, Wu S, Ambs S, Niu Q, Zhang J, Cox NJ, et al. Abstract LB-425: Replication of 18 susceptibility loci of breast cancer in women of African ancestry Cancer Research. 71. DOI: 10.1158/1538-7445.Am2011-Lb-425 |
0.424 |
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| 2011 |
Fedorenko IV, Paraiso KHT, Joseph BD, Fang B, Koomen J, Eschrich S, Nathanson KL, Wubbenhorst B, Mathew R, Messina J, Smalley KSM. Abstract 5111: Integrative phospho-proteomic and genomic analyses identify AXL as a potential biomarker and therapeutic target for NRAS-mutated melanoma Cancer Research. 71: 5111-5111. DOI: 10.1158/1538-7445.Am2011-5111 |
0.338 |
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| 2011 |
Onel K, Best T, Skol AD, Li D, Kirchhoff T, Yasui Y, Bhatia S, Strong LC, Domchek SM, Nathanson KL, Olopade O, Mack TM, Conti DV, Offit K, Cozen W, et al. Abstract 5092: Variants at 6q21 implicate PRDM1 in the etiology of therapy-induced second malignancies after Hodgkin's lymphoma Cancer Research. 71: 5092-5092. DOI: 10.1158/1538-7445.Am2011-5092 |
0.389 |
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| 2011 |
Dondeti VR, Wubbenhorst B, Lal P, Gordan JD, D'Andrea K, Attiyeh EF, Simon MC, Nathanson KL. Abstract 346: Integrative genomic analysis of sporadic clear cell renal cell carcinoma Cancer Research. 71: 346-346. DOI: 10.1158/1538-7445.Am2011-346 |
0.779 |
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| 2010 |
Antoniou AC, Beesley J, McGuffog L, Sinilnikova OM, Healey S, Neuhausen SL, Ding YC, Rebbeck TR, Weitzel JN, Lynch HT, Isaacs C, Ganz PA, Tomlinson G, Olopade OI, Couch FJ, ... ... Nathanson K, et al. Common breast cancer susceptibility alleles and the risk of breast cancer for BRCA1 and BRCA2 mutation carriers: implications for risk prediction. Cancer Research. 70: 9742-54. PMID 21118973 DOI: 10.1158/0008-5472.Can-10-1907 |
0.48 |
|
| 2010 |
Walker LC, Fredericksen ZS, Wang X, Tarrell R, Pankratz VS, Lindor NM, Beesley J, Healey S, Chen X, Stoppa-Lyonnet D, Tirapo C, Giraud S, Mazoyer S, Muller D, ... ... Nathanson KL, et al. Evidence for SMAD3 as a modifier of breast cancer risk in BRCA2 mutation carriers. Breast Cancer Research : Bcr. 12: R102. PMID 21114847 DOI: 10.1186/Bcr2785 |
0.443 |
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| 2010 |
Herlyn M, Nathanson KL. Taking the guesswork out of uveal melanoma. The New England Journal of Medicine. 363: 2256-7. PMID 21083377 DOI: 10.1056/Nejme1010681 |
0.348 |
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| 2010 |
Gaudet MM, Kirchhoff T, Green T, Vijai J, Korn JM, Guiducci C, Segrè AV, McGee K, McGuffog L, Kartsonaki C, Morrison J, Healey S, Sinilnikova OM, Stoppa-Lyonnet D, Mazoyer S, ... ... Nathanson KL, et al. Common genetic variants and modification of penetrance of BRCA2-associated breast cancer. Plos Genetics. 6: e1001183. PMID 21060860 DOI: 10.1371/Journal.Pgen.1001183 |
0.488 |
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| 2010 |
Engel C, Versmold B, Wappenschmidt B, Simard J, Easton DF, Peock S, Cook M, Oliver C, Frost D, Mayes R, Evans DG, Eeles R, Paterson J, Brewer C, ... ... Nathanson KL, et al. Association of the variants CASP8 D302H and CASP10 V410I with breast and ovarian cancer risk in BRCA1 and BRCA2 mutation carriers. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 19: 2859-68. PMID 20978178 DOI: 10.1158/1055-9965.Epi-10-0517 |
0.51 |
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| 2010 |
Brannon AR, Reddy A, Seiler M, Arreola A, Moore DT, Pruthi RS, Wallen EM, Nielsen ME, Liu H, Nathanson KL, Ljungberg B, Zhao H, Brooks JD, Ganesan S, Bhanot G, et al. Molecular Stratification of Clear Cell Renal Cell Carcinoma by Consensus Clustering Reveals Distinct Subtypes and Survival Patterns. Genes & Cancer. 1: 152-163. PMID 20871783 DOI: 10.1177/1947601909359929 |
0.331 |
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| 2010 |
Antoniou AC, Wang X, Fredericksen ZS, McGuffog L, Tarrell R, Sinilnikova OM, Healey S, Morrison J, Kartsonaki C, Lesnick T, Ghoussaini M, Barrowdale D, Peock S, Cook M, ... ... Nathanson KL, et al. A locus on 19p13 modifies risk of breast cancer in BRCA1 mutation carriers and is associated with hormone receptor-negative breast cancer in the general population. Nature Genetics. 42: 885-92. PMID 20852631 DOI: 10.1038/Ng.669 |
0.468 |
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| 2010 |
Bollag G, Hirth P, Tsai J, Zhang J, Ibrahim PN, Cho H, Spevak W, Zhang C, Zhang Y, Habets G, Burton EA, Wong B, Tsang G, West BL, Powell B, ... ... Nathanson KL, et al. Clinical efficacy of a RAF inhibitor needs broad target blockade in BRAF-mutant melanoma. Nature. 467: 596-9. PMID 20823850 DOI: 10.1038/Nature09454 |
0.32 |
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| 2010 |
Crino PB, Aronica E, Baltuch G, Nathanson KL. Biallelic TSC gene inactivation in tuberous sclerosis complex. Neurology. 74: 1716-23. PMID 20498439 DOI: 10.1212/Wnl.0B013E3181E04325 |
0.383 |
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| 2010 |
Wang X, Pankratz VS, Fredericksen Z, Tarrell R, Karaus M, McGuffog L, Pharaoh PD, Ponder BA, Dunning AM, Peock S, Cook M, Oliver C, Frost D, Sinilnikova OM, ... ... Nathanson KL, et al. Common variants associated with breast cancer in genome-wide association studies are modifiers of breast cancer risk in BRCA1 and BRCA2 mutation carriers. Human Molecular Genetics. 19: 2886-97. PMID 20418484 DOI: 10.1093/Hmg/Ddq174 |
0.486 |
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| 2010 |
Nathanson KL. Using genetics and genomics strategies to personalize therapy for cancer: Focus on melanoma Biochemical Pharmacology. 80: 755-761. PMID 20412787 DOI: 10.1016/J.Bcp.2010.04.017 |
0.423 |
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| 2010 |
Rapley EA, Nathanson KL. Predisposition alleles for Testicular Germ Cell Tumour. Current Opinion in Genetics & Development. 20: 225-30. PMID 20303738 DOI: 10.1016/J.Gde.2010.02.006 |
0.406 |
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| 2010 |
Domchek SM, Gaudet MM, Stopfer JE, Fleischaut MH, Powers J, Kauff N, Offit K, Nathanson KL, Robson M. Breast cancer risks in individuals testing negative for a known family mutation in BRCA1 or BRCA2 Breast Cancer Research and Treatment. 119: 409-414. PMID 19885732 DOI: 10.1007/S10549-009-0611-Y |
0.473 |
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| 2010 |
Mai PL, Friedlander M, Tucker K, Phillips KA, Hogg D, Jewett MA, Lohynska R, Daugaard G, Richard S, Bonaïti-Pellié C, Heidenreich A, Albers P, Bodrogi I, Geczi L, Olah E, ... ... Nathanson KL, et al. The International Testicular Cancer Linkage Consortium: a clinicopathologic descriptive analysis of 461 familial malignant testicular germ cell tumor kindred. Urologic Oncology. 28: 492-9. PMID 19162511 DOI: 10.1016/J.Urolonc.2008.10.004 |
0.33 |
|
| 2010 |
Gaudet MM, Kirchhoff T, Green T, Vijai J, Korn JM, Guiducci C, Segrè AV, McGee K, McGuffog L, Kartsonaki C, Morrison J, Healey S, Sinilnikova OM, Stoppa-Lyonnet D, Mazoyer S, ... ... Nathanson KL, et al. Correction: Common Genetic Variants and Modification of Penetrance of BRCA2-Associated Breast Cancer Plos Genetics. 6. DOI: 10.1371/Annotation/B28Cf02D-7196-4A16-8B36-6562A0B84F75 |
0.4 |
|
| 2009 |
Domchek SM, Gaudet MM, Stopfer JE, Kemel Y, Powers J, Balistreri L, Tigges-Cardwell J, Nathanson KL, Offit K, Robson ME. Breast cancer risks in individuals testing negative for known family mutations in BRCA1 or BRCA2. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 27: 11044. PMID 27963986 DOI: 10.1200/Jco.2009.27.15_Suppl.11044 |
0.462 |
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| 2009 |
Melchor L, Saucedo-Cuevas LP, Muñoz-Repeto I, Rodríguez-Pinilla SM, Honrado E, Campoverde A, Palacios J, Nathanson KL, García MJ, Benítez J. Comprehensive characterization of the DNA amplification at 13q34 in human breast cancer reveals TFDP1 and CUL4A as likely candidate target genes. Breast Cancer Research : Bcr. 11: R86. PMID 19995430 DOI: 10.1186/Bcr2456 |
0.419 |
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| 2009 |
Osorio A, Milne RL, Pita G, Peterlongo P, Heikkinen T, Simard J, Chenevix-Trench G, Spurdle AB, Beesley J, Chen X, Healey S, Neuhausen SL, Ding YC, Couch FJ, ... ... Nathanson KL, et al. Evaluation of a candidate breast cancer associated SNP in ERCC4 as a risk modifier in BRCA1 and BRCA2 mutation carriers. Results from the Consortium of Investigators of Modifiers of BRCA1/BRCA2 (CIMBA). British Journal of Cancer. 101: 2048-54. PMID 19920816 DOI: 10.1038/Sj.Bjc.6605416 |
0.493 |
|
| 2009 |
Baybis M, Aronica E, Nathanson KL, Crino PB. Deletion of 15q11.2-15q13.1 in isolated human hemimegalencephaly. Acta Neuropathologica. 118: 821-3. PMID 19851776 DOI: 10.1007/S00401-009-0603-3 |
0.345 |
|
| 2009 |
Neuhausen SL, Brummel S, Ding YC, Singer CF, Pfeiler G, Lynch HT, Nathanson KL, Rebbeck TR, Garber JE, Couch F, Weitzel J, Narod SA, Ganz PA, Daly MB, Godwin AK, et al. Genetic variation in insulin-like growth factor signaling genes and breast cancer risk among BRCA1 and BRCA2 carriers. Breast Cancer Research : Bcr. 11: R76. PMID 19843326 DOI: 10.1186/Bcr2414 |
0.468 |
|
| 2009 |
Sinilnikova OM, Antoniou AC, Simard J, Healey S, Léoné M, Sinnett D, Spurdle AB, Beesley J, Chen X, Greene MH, Loud JT, Lejbkowicz F, Rennert G, Dishon S, ... ... Nathanson KL, et al. The TP53 Arg72Pro and MDM2 309G>T polymorphisms are not associated with breast cancer risk in BRCA1 and BRCA2 mutation carriers. British Journal of Cancer. 101: 1456-60. PMID 19707196 DOI: 10.1038/Sj.Bjc.6605279 |
0.467 |
|
| 2009 |
De Nicolo A, Parisini E, Zhong Q, Dalla Palma M, Stoeckert KA, Domchek SM, Nathanson KL, Caligo MA, Vidal M, Cusick ME, Garber JE. Multimodal assessment of protein functional deficiency supports pathogenicity of BRCA1 p.V1688del. Cancer Research. 69: 7030-7. PMID 19706752 DOI: 10.1158/0008-5472.Can-09-1440 |
0.449 |
|
| 2009 |
Bertout JA, Majmundar AJ, Gordan JD, Lam JC, Ditsworth D, Keith B, Brown EJ, Nathanson KL, Simon MC. HIF2alpha inhibition promotes p53 pathway activity, tumor cell death, and radiation responses. Proceedings of the National Academy of Sciences of the United States of America. 106: 14391-6. PMID 19706526 DOI: 10.1073/Pnas.0907357106 |
0.334 |
|
| 2009 |
Antoniou AC, Sinilnikova OM, McGuffog L, Healey S, Nevanlinna H, Heikkinen T, Simard J, Spurdle AB, Beesley J, Chen X, Neuhausen SL, Ding YC, Couch FJ, Wang X, ... ... Nathanson KL, et al. Common variants in LSP1, 2q35 and 8q24 and breast cancer risk for BRCA1 and BRCA2 mutation carriers. Human Molecular Genetics. 18: 4442-56. PMID 19656774 DOI: 10.1093/Hmg/Ddp372 |
0.498 |
|
| 2009 |
Shah P, Rosen M, Stopfer J, Siegfried J, Kaltman R, Mason B, Armstrong K, Nathanson KL, Schnall M, Domchek SM. Prospective study of breast MRI in BRCA1 and BRCA2 mutation carriers: effect of mutation status on cancer incidence. Breast Cancer Research and Treatment. 118: 539-46. PMID 19609668 DOI: 10.1007/S10549-009-0475-1 |
0.479 |
|
| 2009 |
Rebbeck TR, Mitra N, Domchek SM, Wan F, Chuai S, Friebel TM, Panossian S, Spurdle A, Chenevix-Trench G, Singer CF, Pfeiler G, Neuhausen SL, Lynch HT, Garber JE, ... ... Nathanson KL, et al. Modification of ovarian cancer risk by BRCA1/2-interacting genes in a multicenter cohort of BRCA1/2 mutation carriers. Cancer Research. 69: 5801-10. PMID 19584272 DOI: 10.1158/0008-5472.Can-09-0625 |
0.479 |
|
| 2009 |
Pinnix CC, Lee JT, Liu ZJ, McDaid R, Balint K, Beverly LJ, Brafford PA, Xiao M, Himes B, Zabierowski SE, Yashiro-Ohtani Y, Nathanson KL, Bengston A, Pollock PM, Weeraratna AT, et al. Active Notch1 confers a transformed phenotype to primary human melanocytes. Cancer Research. 69: 5312-20. PMID 19549918 DOI: 10.1158/0008-5472.Can-08-3767 |
0.315 |
|
| 2009 |
Kanetsky PA, Mitra N, Vardhanabhuti S, Li M, Vaughn DJ, Letrero R, Ciosek SL, Doody DR, Smith LM, Weaver J, Albano A, Chen C, Starr JR, Rader DJ, Godwin AK, ... ... Nathanson KL, et al. Common variation in KITLG and at 5q31.3 predisposes to testicular germ cell cancer. Nature Genetics. 41: 811-5. PMID 19483682 DOI: 10.1038/Ng.393 |
0.381 |
|
| 2009 |
Smalley KSM, Nathanson KL, Flaherty KT. Genetic subgrouping of melanoma reveals new opportunities for targeted therapy Cancer Research. 69: 3241-3244. PMID 19351826 DOI: 10.1158/0008-5472.Can-08-4305 |
0.346 |
|
| 2009 |
Greshock J, Nathanson K, Medina A, Ward MR, Herlyn M, Weber BL, Zaks TZ. Distinct patterns of DNA copy number alterations associate with BRAF mutations in melanomas and melanoma-derived cell lines. Genes, Chromosomes & Cancer. 48: 419-28. PMID 19226609 DOI: 10.1002/Gcc.20651 |
0.419 |
|
| 2009 |
Johnatty SE, Couch FJ, Fredericksen Z, Tarrell R, Spurdle AB, Beesley J, Chen X, Gschwantler-Kaulich D, Singer CF, Fuerhauser C, Fink-Retter A, Domchek SM, ... Nathanson KL, et al. No evidence that GATA3 rs570613 SNP modifies breast cancer risk. Breast Cancer Research and Treatment. 117: 371-9. PMID 19082709 DOI: 10.1007/S10549-008-0257-1 |
0.469 |
|
| 2009 |
Smalley KS, Xiao M, Villanueva J, Nguyen TK, Flaherty KT, Letrero R, Van Belle P, Elder DE, Wang Y, Nathanson KL, Herlyn M. CRAF inhibition induces apoptosis in melanoma cells with non-V600E BRAF mutations. Oncogene. 28: 85-94. PMID 18794803 DOI: 10.1038/Onc.2008.362 |
0.342 |
|
| 2009 |
Gabriel CA, Tigges-Cardwell J, Stopfer J, Erlichman J, Nathanson K, Domchek SM. Use of total abdominal hysterectomy and hormone replacement therapy in BRCA1 and BRCA2 mutation carriers undergoing risk-reducing salpingo-oophorectomy. Familial Cancer. 8: 23-8. PMID 18758995 DOI: 10.1007/S10689-008-9208-6 |
0.462 |
|
| 2009 |
Spurdle AB, Deans AJ, Duffy D, Goldgar DE, Chen X, Beesley J, Easton DF, Antoniou AC, Peock S, Cook M, Nathanson KL, Domchek SM, MacArthur GA, Chenevix-Trench G. No evidence that CDKN1B (p27) polymorphisms modify breast cancer risk in BRCA1 and BRCA2 mutation carriers Breast Cancer Research and Treatment. 115: 307-313. PMID 18543099 DOI: 10.1007/S10549-008-0083-5 |
0.48 |
|
| 2008 |
Shah P, Rosen MA, Stopfer J, Siegfried JD, Mason BA, Nathanson KL, Schnall M, Domchek SM. Follow-up MRI screening of BRCA1/2 mutation carriers. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 26: 11000. PMID 27948340 DOI: 10.1200/Jco.2008.26.15_Suppl.11000 |
0.399 |
|
| 2008 |
Gordan JD, Lal P, Dondeti VR, Letrero R, Parekh KN, Oquendo CE, Greenberg RA, Flaherty KT, Rathmell WK, Keith B, Simon MC, Nathanson KL. HIF-alpha effects on c-Myc distinguish two subtypes of sporadic VHL-deficient clear cell renal carcinoma. Cancer Cell. 14: 435-46. PMID 19061835 DOI: 10.1016/J.Ccr.2008.10.016 |
0.739 |
|
| 2008 |
Smalley KS, Lioni M, Dalla Palma M, Xiao M, Desai B, Egyhazi S, Hansson J, Wu H, King AJ, Van Belle P, Elder DE, Flaherty KT, Herlyn M, Nathanson KL. Increased cyclin D1 expression can mediate BRAF inhibitor resistance in BRAF V600E-mutated melanomas. Molecular Cancer Therapeutics. 7: 2876-83. PMID 18790768 DOI: 10.1158/1535-7163.Mct-08-0431 |
0.357 |
|
| 2008 |
Palma MD, Domchek SM, Stopfer J, Erlichman J, Siegfried JD, Tigges-Cardwell J, Mason BA, Rebbeck TR, Nathanson KL. The relative contribution of point mutations and genomic rearrangements in BRCA1 and BRCA2 in high-risk breast cancer families. Cancer Research. 68: 7006-14. PMID 18703817 DOI: 10.1158/0008-5472.Can-08-0599 |
0.431 |
|
| 2008 |
Smalley KS, Contractor R, Nguyen TK, Xiao M, Edwards R, Muthusamy V, King AJ, Flaherty KT, Bosenberg M, Herlyn M, Nathanson KL. Identification of a novel subgroup of melanomas with KIT/cyclin-dependent kinase-4 overexpression. Cancer Research. 68: 5743-52. PMID 18632627 DOI: 10.1158/0008-5472.Can-08-0235 |
0.353 |
|
| 2008 |
Finlay E, Stopfer JE, Burlingame E, Evans KG, Nathanson KL, Weber BL, Armstrong K, Rebbeck TR, Domchek SM. Factors determining dissemination of results and uptake of genetic testing in families with known BRCA1/2 mutations. Genetic Testing. 12: 81-91. PMID 18373407 DOI: 10.1089/Gte.2007.0037 |
0.384 |
|
| 2008 |
Antoniou AC, Spurdle AB, Sinilnikova OM, Healey S, Pooley KA, Schmutzler RK, Versmold B, Engel C, Meindl A, Arnold N, Hofmann W, Sutter C, Niederacher D, Deissler H, Caldes T, ... ... Nathanson KL, et al. Common breast cancer-predisposition alleles are associated with breast cancer risk in BRCA1 and BRCA2 mutation carriers. American Journal of Human Genetics. 82: 937-48. PMID 18355772 DOI: 10.1016/J.Ajhg.2008.02.008 |
0.501 |
|
| 2008 |
Haass NK, Sproesser K, Nguyen TK, Contractor R, Medina CA, Nathanson KL, Herlyn M, Smalley KS. The mitogen-activated protein/extracellular signal-regulated kinase kinase inhibitor AZD6244 (ARRY-142886) induces growth arrest in melanoma cells and tumor regression when combined with docetaxel. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 14: 230-9. PMID 18172275 DOI: 10.1158/1078-0432.Ccr-07-1440 |
0.311 |
|
| 2008 |
Melchor L, Honrado E, García MJ, Alvarez S, Palacios J, Osorio A, Nathanson KL, Benítez J. Distinct genomic aberration patterns are found in familial breast cancer associated with different immunohistochemical subtypes. Oncogene. 27: 3165-75. PMID 18071313 DOI: 10.1038/Sj.Onc.1210975 |
0.459 |
|
| 2008 |
Linger R, Dudakia D, Huddart R, Tucker K, Friedlander M, Phillips KA, Hogg D, Jewett MA, Lohynska R, Daugaard G, Richard S, Chompret A, Stoppa-Lyonnet D, Bonaïti-Pellié C, Heidenreich A, ... ... Nathanson KL, et al. Analysis of the DND1 gene in men with sporadic and familial testicular germ cell tumors. Genes, Chromosomes & Cancer. 47: 247-52. PMID 18069663 DOI: 10.1002/Gcc.20526 |
0.386 |
|
| 2007 |
Melchor L, Honrado E, Huang J, Alvarez S, Naylor TL, García MJ, Osorio A, Blesa D, Stratton MR, Weber BL, Cigudosa JC, Rahman N, Nathanson KL, Benítez J. Estrogen receptor status could modulate the genomic pattern in familial and sporadic breast cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 13: 7305-13. PMID 18094411 DOI: 10.1158/1078-0432.Ccr-07-0711 |
0.459 |
|
| 2007 |
Antoniou AC, Sinilnikova OM, Simard J, Léoné M, Dumont M, Neuhausen SL, Struewing JP, Stoppa-Lyonnet D, Barjhoux L, Hughes DJ, Coupier I, Belotti M, Lasset C, Bonadona V, Bignon YJ, ... ... Nathanson KL, et al. RAD51 135G-->C modifies breast cancer risk among BRCA2 mutation carriers: results from a combined analysis of 19 studies. American Journal of Human Genetics. 81: 1186-200. PMID 17999359 DOI: 10.1086/522611 |
0.473 |
|
| 2007 |
Greshock J, Feng B, Nogueira C, Ivanova E, Perna I, Nathanson K, Protopopov A, Weber BL, Chin L. A comparison of DNA copy number profiling platforms. Cancer Research. 67: 10173-80. PMID 17968032 DOI: 10.1158/0008-5472.Can-07-2102 |
0.34 |
|
| 2007 |
Pujana MA, Han JD, Starita LM, Stevens KN, Tewari M, Ahn JS, Rennert G, Moreno V, Kirchhoff T, Gold B, Assmann V, Elshamy WM, Rual JF, Levine D, Rozek LS, ... ... Nathanson KL, et al. Network modeling links breast cancer susceptibility and centrosome dysfunction. Nature Genetics. 39: 1338-49. PMID 17922014 DOI: 10.1038/Ng.2007.2 |
0.457 |
|
| 2007 |
Spittle C, Ward MR, Nathanson KL, Gimotty PA, Rappaport E, Brose MS, Medina A, Letrero R, Herlyn M, Edwards RH. Application of a BRAF pyrosequencing assay for mutation detection and copy number analysis in malignant melanoma. The Journal of Molecular Diagnostics : Jmd. 9: 464-71. PMID 17690212 DOI: 10.2353/Jmoldx.2007.060191 |
0.404 |
|
| 2007 |
Couch FJ, Sinilnikova O, Vierkant RA, Pankratz VS, Fredericksen ZS, Stoppa-Lyonnet D, Coupier I, Hughes D, Hardouin A, Berthet P, Peock S, Cook M, Baynes C, Hodgson S, Morrison PJ, ... ... Nathanson K, et al. AURKA F31I polymorphism and breast cancer risk in BRCA1 and BRCA2 mutation carriers: a consortium of investigators of modifiers of BRCA1/2 study. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 16: 1416-21. PMID 17627006 DOI: 10.1158/1055-9965.EPI-07-0129 |
0.418 |
|
| 2007 |
Tchou J, Ward MR, Volpe P, Palma MD, Medina CA, Sargen M, Sonnad SS, Godwin AK, Daly M, Winchester DJ, Garber J, Weber BL, Domchek S, Nathanson KL. Large genomic rearrangement in BRCA1 and BRCA2 and clinical characteristics of men with breast cancer in the United States. Clinical Breast Cancer. 7: 627-33. PMID 17592676 DOI: 10.3816/Cbc.2007.N.021 |
0.478 |
|
| 2007 |
Greshock J, Nathanson K, Martin AM, Zhang L, Coukos G, Weber BL, Zaks TZ. Cancer cell lines as genetic models of their parent histology: analyses based on array comparative genomic hybridization. Cancer Research. 67: 3594-600. PMID 17440070 DOI: 10.1158/0008-5472.Can-06-3674 |
0.374 |
|
| 2007 |
Carvalho MA, Marsillac SM, Karchin R, Manoukian S, Grist S, Swaby RF, Urmenyi TP, Rondinelli E, Silva R, Gayol L, Baumbach L, Sutphen R, Pickard-Brzosowicz JL, Nathanson KL, Sali A, et al. Determination of cancer risk associated with germ line BRCA1 missense variants by functional analysis. Cancer Research. 67: 1494-501. PMID 17308087 DOI: 10.1158/0008-5472.Can-06-3297 |
0.462 |
|
| 2007 |
Domchek SM, Simon MS, Hughes Halbert C, Rebbeck TR, Nathanson KL. Pathologic predictors of BRCA1/ BRCA2 (B1/B2) mutations in African-American (AA) women with early-onset breast cancer (BC) Journal of Clinical Oncology. 25: 10549-10549. DOI: 10.1200/Jco.2007.25.18_Suppl.10549 |
0.375 |
|
| 2006 |
Thompson D, Seal S, Schutte M, McGuffog L, Barfoot R, Renwick A, Eeles R, Sodha N, Houlston R, Shanley S, Klijn J, Wasielewski M, Chang-Claude J, Futreal PA, Weber BL, ... Nathanson KL, et al. A multicenter study of cancer incidence in CHEK2 1100delC mutation carriers. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 15: 2542-5. PMID 17164383 DOI: 10.1158/1055-9965.Epi-06-0687 |
0.462 |
|
| 2006 |
Brooks GA, Stopfer JE, Erlichman J, Davidson R, Nathanson KL, Domchek SM. Childhood cancer in families with and without BRCA1 or BRCA2 mutations ascertained at a high-risk breast cancer clinic. Cancer Biology & Therapy. 5: 1098-102. PMID 16931905 DOI: 10.4161/Cbt.5.9.3167 |
0.484 |
|
| 2006 |
Hoek KS, Schlegel NC, Brafford P, Sucker A, Ugurel S, Kumar R, Weber BL, Nathanson KL, Phillips DJ, Herlyn M, Schadendorf D, Dummer R. Metastatic potential of melanomas defined by specific gene expression profiles with no BRAF signature. Pigment Cell Research / Sponsored by the European Society For Pigment Cell Research and the International Pigment Cell Society. 19: 290-302. PMID 16827748 DOI: 10.1111/J.1600-0749.2006.00322.X |
0.336 |
|
| 2006 |
Smith P, McGuffog L, Easton DF, Mann GJ, Pupo GM, Newman B, Chenevix-Trench G, Szabo C, Southey M, Renard H, Odefrey F, Lynch H, Stoppa-Lyonnet D, Couch F, ... ... Nathanson KL, et al. A genome wide linkage search for breast cancer susceptibility genes. Genes, Chromosomes & Cancer. 45: 646-55. PMID 16575876 DOI: 10.1002/Gcc.20330 |
0.486 |
|
| 2006 |
Abbott M, Nathanson KL, Nightingale S, Maher ER, Greenstein RM. The von Hippel-Lindau (VHL) germline mutation V84L manifests as early-onset bilateral pheochromocytoma. American Journal of Medical Genetics Part A. 140: 685-690. PMID 16502427 DOI: 10.1002/Ajmg.A.31116 |
0.389 |
|
| 2006 |
Crockford GP, Linger R, Hockley S, Dudakia D, Johnson L, Huddart R, Tucker K, Friedlander M, Phillips KA, Hogg D, Jewett MA, Lohynska R, Daugaard G, Richard S, Chompret A, ... ... Nathanson KL, et al. Genome-wide linkage screen for testicular germ cell tumour susceptibility loci. Human Molecular Genetics. 15: 443-51. PMID 16407372 DOI: 10.1093/Hmg/Ddi459 |
0.342 |
|
| 2006 |
Tchou J, Sonnad S, Sargen M, Weber B, Nathanson K, Domchek S. Contralateral prophylactic mastectomy in affected carriers of deleterious BRCA1 or BRCA2 mutations: Does timing of genetic testing matter? Journal of Clinical Oncology. 24: 10512-10512. DOI: 10.1200/Jco.2006.24.18_Suppl.10512 |
0.457 |
|
| 2006 |
Brooks GA, Stopfer JE, Erlichman J, Davidson R, Nathanson KL, Domchek SM. Childhood cancer in families with and without germline BRCA1/2 mutations ascertained at a high-risk breast cancer clinic Journal of Clinical Oncology. 24: 10013-10013. DOI: 10.1200/Jco.2006.24.18_Suppl.10013 |
0.488 |
|
| 2005 |
Nathanson KL, Kanetsky PA, Hawes R, Vaughn DJ, Letrero R, Tucker K, Friedlander M, Phillips KA, Hogg D, Jewett MA, Lohynska R, Daugaard G, Richard S, Chompret A, Bonaïti-Pellié C, et al. The Y deletion gr/gr and susceptibility to testicular germ cell tumor. American Journal of Human Genetics. 77: 1034-43. PMID 16380914 DOI: 10.1086/498455 |
0.398 |
|
| 2005 |
Plon SE, Nathanson K. Inherited susceptibility for pediatric cancer. Cancer Journal. 11: 255-267. PMID 16197716 DOI: 10.1097/00130404-200507000-00002 |
0.451 |
|
| 2005 |
McClain MR, Nathanson KL, Palomaki GE, Haddow JE. An evaluation of BRCA1 and BRCA2 founder mutations penetrance estimates for breast cancer among Ashkenazi Jewish women. Genetics in Medicine : Official Journal of the American College of Medical Genetics. 7: 34-9. PMID 15654226 DOI: 10.1097/01.Gim.0000151156.14983.08 |
0.45 |
|
| 2005 |
McClain MR, Palomaki GE, Nathanson KL, Haddow JE. Adjusting the estimated proportion of breast cancer cases associated with BRCA1 and BRCA2 mutations: public health implications. Genetics in Medicine : Official Journal of the American College of Medical Genetics. 7: 28-33. PMID 15654225 DOI: 10.1097/01.Gim.0000151155.36470.Ff |
0.452 |
|
| 2005 |
Pujana M, Han J, Starita L, Tewari M, Ahn J, Assmann V, ElShamy W, Rual J, Gelman R, Gunsalus K, Greenberg R, Bohian B, Bertin N, Ayivi-Guedehoussou N, Nathanson K, et al. A model of the BRCA1/BRCA2 network Breast Cancer Research. 7: 1-1. DOI: 10.1186/Bcr1195 |
0.419 |
|
| 2004 |
Nathanson KL, Vaughn DJ. Somatic genetic changes in association with testicular germ cell tumor prognosis. Cancer Biology & Therapy. 3: 1159-61. PMID 15640621 DOI: 10.4161/Cbt.3.11.1298 |
0.319 |
|
| 2004 |
Huang J, Domchek SM, Brose MS, Rebbeck TR, Nathanson KL, Weber BL. Germline CHEK2*1100delC mutations in breast cancer patients with multiple primary cancers Journal of Medical Genetics. 41. PMID 15520402 DOI: 10.1136/Jmg.2004.022913 |
0.475 |
|
| 2004 |
Nathanson KL, Kanetsky PA, Letrero R, Robertson K, Ohr EE, Manson J, Malkowicz SB, Vaughn DJ. 1177: Testicular Cancer Susceptidility and Variants in Androgen Metabolism Genes The Journal of Urology. 171: 310-310. DOI: 10.1016/S0022-5347(18)38414-3 |
0.355 |
|
| 2003 |
Bryant J, Farmer J, Kessler LJ, Townsend RR, Nathanson KL. Pheochromocytoma: The Expanding Genetic Differential Diagnosis Journal of the National Cancer Institute. 95: 1196-1204. PMID 12928344 DOI: 10.1093/Jnci/Djg024 |
0.413 |
|
| 2003 |
Schutte M, Seal S, Barfoot R, Meijers-Heijboer H, Wasielewski M, Evans DG, Eccles D, Meijers C, Lohman F, Klijn J, Van Den Ouweland A, Futreal PA, Nathanson KL, Weber BL, Easton DF, et al. Variants in CHEK2 other than 1100delC do not make a major contribution to breast cancer susceptibility American Journal of Human Genetics. 72: 1023-1028. PMID 12610780 DOI: 10.1086/373965 |
0.461 |
|
| 2002 |
Brose MS, Rebbeck TR, Calzone KA, Stopfer JE, Nathanson KL, Weber BL. Cancer risk estimates for BCRA1 mutation carriers identified in a risk evaluation program Journal of the National Cancer Institute. 94: 1365-1372. PMID 12237282 DOI: 10.1093/Jnci/94.18.1365 |
0.456 |
|
| 2002 |
Nathanson KL, Shugart YY, Omaruddin R, Szabo C, Goldgar D, Rebbeck TR, Weber BL. CGH-targeted linkage analysis reveals a possible BRCA1 modifier locus on chromosome 5q. Human Molecular Genetics. 11: 1327-32. PMID 12019214 DOI: 10.1093/Hmg/11.11.1327 |
0.492 |
|
| 2002 |
Meijers-Heijboer H, van den Ouweland A, Klijn J, Wasielewski M, de Snoo A, Oldenburg R, Hollestelle A, Houben M, Crepin E, van Veghel-Plandsoen M, Elstrodt F, van Duijn C, Bartels C, Meijers C, Schutte M, ... ... Nathanson KL, et al. Low-penetrance susceptibility to breast cancer due to CHEK2(*)1100delC in noncarriers of BRCA1 or BRCA2 mutations. Nature Genetics. 31: 55-9. PMID 11967536 DOI: 10.1038/Ng879 |
0.509 |
|
| 2002 |
Shih HA, Couch FJ, Nathanson KL, Anne Blackwood M, Rebbeck TR, Armstrong KA, Calzone K, Stopfer J, Seal S, Stratton MR, Weber BL. BRCA1 and BRCA2 mutation frequency in women evaluated in a breast cancer risk evaluation clinic Journal of Clinical Oncology. 20: 994-999. PMID 11844822 DOI: 10.1200/Jco.20.4.994 |
0.484 |
|
| 2002 |
Thompson D, Szabo CI, Mangion J, Oldenburg RA, Odefrey F, Seal S, Barfoot R, Kroeze-Jansema K, Teare D, Rahman N, Renard H, Mann G, Hopper JL, Buys SS, Andrulis IL, ... ... Nathanson KL, et al. Evaluation of linkage of breast cancer to the putative BRCA3 locus on chromosome 13q21 in 128 multiple case families from the Breast Cancer Linkage Consortium. Proceedings of the National Academy of Sciences of the United States of America. 99: 827-31. PMID 11792833 DOI: 10.1073/Pnas.012584499 |
0.451 |
|
| 2001 |
Eng C, Brody LC, Wagner TM, Devilee P, Vijg J, Szabo C, Tavtigian SV, Nathanson KL, Ostrander E, Frank TS. Interpreting epidemiological research: blinded comparison of methods used to estimate the prevalence of inherited mutations in BRCA1. Journal of Medical Genetics. 38: 824-33. PMID 11748305 DOI: 10.1136/Jmg.38.12.824 |
0.393 |
|
| 2001 |
Martin AM, Blackwood MA, Antin-Ozerkis D, Shih HA, Calzone K, Colligon TA, Seal S, Collins N, Stratton MR, Weber BL, Nathanson KL. Germline mutations in BRCA1 and BRCA2 in breast-ovarian families from a breast cancer risk evaluation clinic. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 19: 2247-53. PMID 11304778 DOI: 10.1200/Jco.2001.19.8.2247 |
0.472 |
|
| 2001 |
Nathanson KL, Weber BL. "Other" breast cancer susceptibility genes: searching for more holy grail. Human Molecular Genetics. 10: 715-20. PMID 11257104 DOI: 10.1093/Hmg/10.7.715 |
0.5 |
|
| 2000 |
Rebbeck TR, Walker AH, Zeigler-Johnson C, Weisburg S, Martin AM, Nathanson KL, Wein AJ, Malkowicz SB. Association of HPC2/ELAC2 genotypes and prostate cancer. American Journal of Human Genetics. 67: 1014-9. PMID 10986046 DOI: 10.1086/303096 |
0.342 |
|
| 2000 |
Unger MA, Nathanson KL, Calzone K, Antin-Ozerkis D, Shih HA, Martin AM, Lenoir GM, Mazoyer S, Weber BL. Screening for genomic rearrangements in families with breast and ovarian cancer identifies BRCA1 mutations previously missed by conformation-sensitive gel electrophoresis or sequencing. American Journal of Human Genetics. 67: 841-50. PMID 10978226 DOI: 10.1086/303076 |
0.454 |
|
| 2000 |
Rahman N, Teare MD, Seal S, Renard H, Mangion J, Cour C, Thompson D, Shugart Y, Eccles D, Devilee P, Meijers H, Nathanson KL, Neuhausen SL, Weber B, Chang-Claude J, et al. Absence of evidence for a familial breast cancer susceptibility gene at chromosome 8p12-p22. Oncogene. 19: 4170-4173. PMID 10962578 DOI: 10.1038/Sj.Onc.1203735 |
0.408 |
|
| 2000 |
Weber BL, Nathanson KL. Low penetrance genes associated with increased risk for breast cancer. European Journal of Cancer (Oxford, England : 1990). 36: 1193-9. PMID 10882856 DOI: 10.1016/S0959-8049(00)00082-4 |
0.499 |
|
| 2000 |
Mazoyer S, Leary J, Kirk J, Fleischmann E, Wagner T, Claes K, Messiaen L, Foulkes W, Desrochers M, Simard J, Phelan CM, Kwan E, Narod SA, Vahteristo P, Nevanlinna H, ... ... Nathanson K, et al. The exon 13 duplication in the BRCA1 gene is a founder mutation present in geographicaly diverse populations American Journal of Human Genetics. 67: 207-212. PMID 10827109 DOI: 10.1086/302974 |
0.394 |
|
| 1999 |
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