Parents
Sign in to add mentor| Aneil Agrawal | grad student | University of Toronto | |
| Sarah (Sally) P. Otto | post-doc | UBC | |
| Michael C. Whitlock | post-doc | UBC |
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Publications
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| Bao K, Strayer BR, Braker NP, et al. (2024) Mutations in yeast are deleterious on average regardless of the degree of adaptation to the testing environment. Proceedings. Biological Sciences. 291: 20240064 |
| Sharp NP, Smith DR, Driscoll G, et al. (2023) Contribution of Spontaneous Mutations to Quantitative and Molecular Variation at the Highly Repetitive rDNA Locus in Yeast. Genome Biology and Evolution. 15 |
| Bao K, Melde RH, Sharp NP. (2022) Are mutations usually deleterious? A perspective on the fitness effects of mutation accumulation. Evolutionary Ecology. 36: 753-766 |
| Melde RH, Bao K, Sharp NP. (2022) Recent insights into the evolution of mutation rates in yeast. Current Opinion in Genetics & Development. 76: 101953 |
| Sharp N. (2022) Mutations matter even if proteins stay the same. Nature |
| Sandell L, Sharp NP. (2022) Fitness Effects of Mutations: An Assessment of PROVEAN Predictions Using Mutation Accumulation Data. Genome Biology and Evolution. 14 |
| Gerstein AC, Sharp NP. (2021) The population genetics of ploidy change in unicellular fungi. Fems Microbiology Reviews |
| Sharp NP, Whitlock MC. (2019) No evidence of positive assortative mating for genetic quality in fruit flies. Proceedings. Biological Sciences. 286: 20191474 |
| Sharp NP, Agrawal AF. (2018) An experimental test of the mutation-selection balance model for the maintenance of genetic variance in fitness components. Proceedings. Biological Sciences. 285 |
| Sharp NP, Sandell L, James CG, et al. (2018) The genome-wide rate and spectrum of spontaneous mutations differ between haploid and diploid yeast. Proceedings of the National Academy of Sciences of the United States of America |