Nathaniel Sharp

University of Toronto, Toronto, ON, Canada 
"Nathaniel Sharp"
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Bao K, Melde RH, Sharp NP. (2022) Are mutations usually deleterious? A perspective on the fitness effects of mutation accumulation. Evolutionary Ecology. 36: 753-766
Melde RH, Bao K, Sharp NP. (2022) Recent insights into the evolution of mutation rates in yeast. Current Opinion in Genetics & Development. 76: 101953
Sharp N. (2022) Mutations matter even if proteins stay the same. Nature
Sandell L, Sharp NP. (2022) Fitness Effects of Mutations: An Assessment of PROVEAN Predictions Using Mutation Accumulation Data. Genome Biology and Evolution. 14
Gerstein AC, Sharp NP. (2021) The population genetics of ploidy change in unicellular fungi. Fems Microbiology Reviews
Sharp NP, Whitlock MC. (2019) No evidence of positive assortative mating for genetic quality in fruit flies. Proceedings. Biological Sciences. 286: 20191474
Sharp NP, Agrawal AF. (2018) An experimental test of the mutation-selection balance model for the maintenance of genetic variance in fitness components. Proceedings. Biological Sciences. 285
Sharp NP, Sandell L, James CG, et al. (2018) The genome-wide rate and spectrum of spontaneous mutations differ between haploid and diploid yeast. Proceedings of the National Academy of Sciences of the United States of America
Sharp NP, Otto SP. (2018) Evolution: Zeroing In on the Rate of Genome Doubling. Current Biology : Cb. 28: R320-R322
Gilbert KJ, Sharp NP, Angert AL, et al. (2017) Local Adaptation Interacts with Expansion Load during Range Expansion: Maladaptation Reduces Expansion Load. The American Naturalist. 189: 368-380
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