Guido Franzoso - Publications

Affiliations: 
University of Chicago, Chicago, IL 
Area:
Molecular Biology, Cell Biology, Biochemistry

84 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Verzella D, Cornice J, Arboretto P, Vecchiotti D, Di Vito Nolfi M, Capece D, Zazzeroni F, Franzoso G. The NF-κB Pharmacopeia: Novel Strategies to Subdue an Intractable Target. Biomedicines. 10. PMID 36140335 DOI: 10.3390/biomedicines10092233  0.507
2022 Capece D, Verzella D, Flati I, Arboretto P, Cornice J, Franzoso G. NF-κB: blending metabolism, immunity, and inflammation. Trends in Immunology. 43: 757-775. PMID 35965153 DOI: 10.1016/j.it.2022.07.004  0.321
2021 Tornatore L, Capece D, Sandomenico A, Verzella D, Vecchiotti D, Zazzeroni F, Ruvo M, Franzoso G. The Screening of Combinatorial Peptide Libraries for Targeting Key Molecules or Protein-Protein Interactions in the NF-κB Pathway. Methods in Molecular Biology (Clifton, N.J.). 2366: 343-356. PMID 34236649 DOI: 10.1007/978-1-0716-1669-7_21  0.421
2021 Capece D, Verzella D, Begalli F, Bennett J, D'Andrea D, Vecchiotti D, Zazzeroni F, Franzoso G. Extracellular Flux Analysis to Investigate the Impact of NF-κB on Mitochondrial Respiration in Colorectal Carcinoma (CRC). Methods in Molecular Biology (Clifton, N.J.). 2366: 293-303. PMID 34236646 DOI: 10.1007/978-1-0716-1669-7_18  0.32
2021 Capece D, D'Andrea D, Begalli F, Goracci L, Tornatore L, Alexander JL, Di Veroli A, Leow SC, Vaiyapuri TS, Ellis JK, Verzella D, Bennett J, Savino L, Ma Y, McKenzie JS, ... ... Franzoso G, et al. Enhanced triacylglycerol catabolism by Carboxylesterase 1 promotes aggressive colorectal carcinoma. The Journal of Clinical Investigation. PMID 33878036 DOI: 10.1172/JCI137845  0.358
2020 Rajpoot S, Bennett J, Franzoso G, Verzella D, Begalli F, Capece D, D'Andrea D. Reprogramming immunosuppressive tumour-associated dendritic cells with GADD45β inhibitors. Clinical Medicine (London, England). 20: s116. PMID 32409418 DOI: 10.7861/Clinmed.20-2-S116  0.305
2020 Verzella D, Pescatore A, Capece D, Vecchiotti D, Ursini MV, Franzoso G, Alesse E, Zazzeroni F. Life, death, and autophagy in cancer: NF-κB turns up everywhere. Cell Death & Disease. 11: 210. PMID 32231206 DOI: 10.1038/S41419-020-2399-Y  0.572
2019 Capece D, Verzella D, Di Francesco B, Alesse E, Franzoso G, Zazzeroni F. NF-κB and mitochondria cross paths in cancer: Mitochondrial metabolism and beyond. Seminars in Cell & Developmental Biology. PMID 31132468 DOI: 10.1016/J.Semcdb.2019.05.021  0.493
2019 Tornatore L, Capece D, D'Andrea D, Begalli F, Verzella D, Bennett J, Acton G, Campbell EA, Kelly J, Tarbit M, Adams N, Bannoo S, Leonardi A, Sandomenico A, Raimondo D, ... ... Franzoso G, et al. Preclinical toxicology and safety pharmacology of the first-in-class GADD45β/MKK7 inhibitor and clinical candidate, DTP3. Toxicology Reports. 6: 369-379. PMID 31080744 DOI: 10.1016/J.Toxrep.2019.04.006  0.499
2018 Tornatore L, Capece D, D'Andrea D, Begalli F, Verzella D, Bennett J, Acton G, Campbell EA, Kelly J, Tarbit M, Adams N, Bannoo S, Leonardi A, Sandomenico A, Raimondo D, ... ... Franzoso G, et al. Clinical proof of concept for a safe and effective NF-κB-targeting strategy in multiple myeloma. British Journal of Haematology. PMID 30255568 DOI: 10.1111/Bjh.15569  0.445
2018 Rega C, Russo R, Focà A, Sandomenico A, Iaccarino E, Raimondo D, Milanetti E, Tornatore L, Franzoso G, Pedone PV, Ruvo M, Chambery A. Probing the interaction interface of the GADD45β/MKK7 and MKK7/DTP3 complexes by chemical cross-linking mass spectrometry. International Journal of Biological Macromolecules. 114: 114-123. PMID 29572137 DOI: 10.1016/J.Ijbiomac.2018.03.090  0.318
2017 Verzella D, Bennett J, Fischietti M, Thotakura AK, Recordati C, Pasqualini F, Capece D, Vecchiotti D, D'Andrea D, Di Francesco B, De Maglie M, Begalli F, Tornatore L, Papa S, Lawrence T, ... ... Franzoso G, et al. GADD45β loss ablates innate immunosuppression in cancer. Cancer Research. PMID 29279355 DOI: 10.1158/0008-5472.Can-17-1833  0.41
2017 Bennett J, Capece D, Begalli F, Verzella D, D'Andrea D, Tornatore L, Franzoso G. NF-κB in the crosshairs: Rethinking an old riddle. The International Journal of Biochemistry & Cell Biology. 95: 108-112. PMID 29277662 DOI: 10.1016/J.Biocel.2017.12.020  0.562
2017 Begalli F, Bennett J, Capece D, Verzella D, D'Andrea D, Tornatore L, Franzoso G. Unlocking the NF-κB Conundrum: Embracing Complexity to Achieve Specificity. Biomedicines. 5. PMID 28829404 DOI: 10.3390/Biomedicines5030050  0.571
2015 Koh CM, Khattar E, Leow SC, Liu CY, Muller J, Ang WX, Li Y, Franzoso G, Li S, Guccione E, Tergaonkar V. Telomerase regulates MYC-driven oncogenesis independent of its reverse transcriptase activity. The Journal of Clinical Investigation. 125: 2109-22. PMID 25893605 DOI: 10.1172/Jci79134  0.391
2015 Tornatore L, Acton G, Adams N, Campbell EA, Kelly J, Szydlo RM, Tarbit M, Bannoo S, D'Andrea D, Capece D, Sandomenico A, Dyson J, Leonardi A, Driessen C, Ruvo M, ... ... Franzoso G, et al. Cancer-Selective Targeting of the NF-κB Survival Pathway in Multiple Myeloma with the GADD45β/MKK7 Inhibitor, DTP3 Blood. 126: 868-868. DOI: 10.1182/Blood.V126.23.868.868  0.481
2014 Tornatore L, Sandomenico A, Raimondo D, Low C, Rocci A, Tralau-Stewart C, Capece D, D'Andrea D, Bua M, Boyle E, van Duin M, Zoppoli P, Jaxa-Chamiec A, Thotakura AK, Dyson J, ... ... Franzoso G, et al. Cancer-Selective Targeting of the NF-κB Survival Pathway with GADD45β/MKK7 Inhibitors. Cancer Cell. 26: 938. PMID 28898681 DOI: 10.1016/j.ccell.2014.11.021  0.36
2014 Tornatore L, Sandomenico A, Raimondo D, Low C, Rocci A, Tralau-Stewart C, Capece D, D'Andrea D, Bua M, Boyle E, van Duin M, Zoppoli P, Jaxa-Chamiec A, Thotakura AK, Dyson J, ... ... Franzoso G, et al. Cancer-selective targeting of the NF-κB survival pathway with GADD45β/MKK7 inhibitors. Cancer Cell. 26: 495-508. PMID 25314077 DOI: 10.1016/J.Ccr.2014.07.027  0.521
2014 Ling GS, Bennett J, Woollard KJ, Szajna M, Fossati-Jimack L, Taylor PR, Scott D, Franzoso G, Cook HT, Botto M. Integrin CD11b positively regulates TLR4-induced signalling pathways in dendritic cells but not in macrophages. Nature Communications. 5: 3039. PMID 24423728 DOI: 10.1038/Ncomms4039  0.428
2013 Barbarulo A, Iansante V, Chaidos A, Naresh K, Rahemtulla A, Franzoso G, Karadimitris A, Haskard DO, Papa S, Bubici C. Poly(ADP-ribose) polymerase family member 14 (PARP14) is a novel effector of the JNK2-dependent pro-survival signal in multiple myeloma. Oncogene. 32: 4231-42. PMID 23045269 DOI: 10.1038/Onc.2012.448  0.455
2012 Tornatore L, Thotakura AK, Bennett J, Moretti M, Franzoso G. The nuclear factor kappa B signaling pathway: integrating metabolism with inflammation. Trends in Cell Biology. 22: 557-66. PMID 22995730 DOI: 10.1016/J.Tcb.2012.08.001  0.514
2012 Moretti M, Bennett J, Tornatore L, Thotakura AK, Franzoso G. Cancer: NF-κB regulates energy metabolism. The International Journal of Biochemistry & Cell Biology. 44: 2238-43. PMID 22903018 DOI: 10.1016/J.Biocel.2012.08.002  0.531
2012 Mauro C, Leow SC, Anso E, Rocha S, Thotakura AK, Tornatore L, Moretti M, De Smaele E, Beg AA, Tergaonkar V, Chandel NS, Franzoso G. The Control of Cell Energy Metabolism by NF-Kb Transcription Factors Transplantation Journal. 94: 493. DOI: 10.1097/00007890-201211271-00943  0.43
2011 Mauro C, Leow SC, Anso E, Rocha S, Thotakura AK, Tornatore L, Moretti M, De Smaele E, Beg AA, Tergaonkar V, Chandel NS, Franzoso G. NF-κB controls energy homeostasis and metabolic adaptation by upregulating mitochondrial respiration. Nature Cell Biology. 13: 1272-9. PMID 21968997 DOI: 10.1038/Ncb2324  0.496
2011 Luo Y, Boyle DL, Hammaker D, Edgar M, Franzoso G, Firestein GS. Suppression of collagen-induced arthritis in growth arrest and DNA damage-inducible protein 45β-deficient mice. Arthritis and Rheumatism. 63: 2949-55. PMID 21702006 DOI: 10.1002/Art.30497  0.371
2010 Ma L, Mauro C, Cornish GH, Chai JG, Coe D, Fu H, Patton D, Okkenhaug K, Franzoso G, Dyson J, Nourshargh S, Marelli-Berg FM. Ig gene-like molecule CD31 plays a nonredundant role in the regulation of T-cell immunity and tolerance. Proceedings of the National Academy of Sciences of the United States of America. 107: 19461-6. PMID 20978210 DOI: 10.1073/Pnas.1011748107  0.311
2010 Yang H, Rivera Z, Jube S, Nasu M, Bertino P, Goparaju C, Franzoso G, Lotze MT, Krausz T, Pass HI, Bianchi ME, Carbone M. Programmed necrosis induced by asbestos in human mesothelial cells causes high-mobility group box 1 protein release and resultant inflammation. Proceedings of the National Academy of Sciences of the United States of America. 107: 12611-6. PMID 20616036 DOI: 10.1073/Pnas.1006542107  0.443
2009 Svensson CI, Inoue T, Hammaker D, Fukushima A, Papa S, Franzoso G, Schett G, Corr M, Boyle DL, Firestein GS. Gadd45beta deficiency in rheumatoid arthritis: enhanced synovitis through JNK signaling. Arthritis and Rheumatism. 60: 3229-40. PMID 19877043 DOI: 10.1002/Art.24887  0.347
2009 Papa S, Bubici C, Zazzeroni F, Franzoso G. Mechanisms of liver disease: Cross-talk between the NF-κB and JNK pathways Biological Chemistry. 390: 965-976. PMID 19642868 DOI: 10.1515/Bc.2009.111  0.503
2009 Mauro C, Zazzeroni F, Papa S, Bubici C, Franzoso G. The NF-kappaB transcription factor pathway as a therapeutic target in cancer: methods for detection of NF-kappaB activity. Methods in Molecular Biology (Clifton, N.J.). 512: 169-207. PMID 19347278 DOI: 10.1007/978-1-60327-530-9_10  0.648
2009 Gilmore TD, Perkins ND, Franzoso G. Getting away from it all in Capri: The 2008 EMBO workshop on NF-κB Cell Death and Differentiation. 16: 651-654. PMID 19287453 DOI: 10.1038/Cdd.2009.3  0.486
2008 Papa S, Zazzeroni F, Fu YX, Bubici C, Alvarez K, Dean K, Christiansen PA, Anders RA, Franzoso G. Gadd45beta promotes hepatocyte survival during liver regeneration in mice by modulating JNK signaling. The Journal of Clinical Investigation. 118: 1911-23. PMID 18382767 DOI: 10.1172/Jci33913  0.42
2008 Tornatore L, Marasco D, Dathan N, Vitale RM, Benedetti E, Papa S, Franzoso G, Ruvo M, Monti SM. Gadd45 beta forms a homodimeric complex that binds tightly to MKK7. Journal of Molecular Biology. 378: 97-111. PMID 18343408 DOI: 10.1016/J.Jmb.2008.01.074  0.329
2007 Kuntzen C, Zazzeroni F, Pham CG, Papa S, Bubici C, Knabb JR, Franzoso G. A method for isolating prosurvival targets of NF-kappaB/Rel transcription factors. Methods in Molecular Biology (Clifton, N.J.). 399: 99-124. PMID 18309928 DOI: 10.1007/978-1-59745-504-6_8  0.797
2007 Papa S, Monti SM, Vitale RM, Bubici C, Jayawardena S, Alvarez K, De Smaele E, Dathan N, Pedone C, Ruvo M, Franzoso G. Insights into the structural basis of the GADD45beta-mediated inactivation of the JNK kinase, MKK7/JNKK2. The Journal of Biological Chemistry. 282: 19029-41. PMID 17485467 DOI: 10.1074/Jbc.M703112200  0.494
2007 Pham CG, Bubici C, Zazzeroni F, Knabb JR, Papa S, Kuntzen C, Franzoso G. Upregulation of Twist-1 by NF-kappaB blocks cytotoxicity induced by chemotherapeutic drugs. Molecular and Cellular Biology. 27: 3920-35. PMID 17403902 DOI: 10.1128/Mcb.01219-06  0.826
2006 Bubici C, Papa S, Dean K, Franzoso G. Mutual cross-talk between reactive oxygen species and nuclear factor-kappa B: molecular basis and biological significance. Oncogene. 25: 6731-48. PMID 17072325 DOI: 10.1038/Sj.Onc.1209936  0.639
2006 Yang H, Bocchetta M, Kroczynska B, Elmishad AG, Chen Y, Liu Z, Bubici C, Mossman BT, Pass HI, Testa JR, Franzoso G, Carbone M. TNF-alpha inhibits asbestos-induced cytotoxicity via a NF-kappaB-dependent pathway, a possible mechanism for asbestos-induced oncogenesis. Proceedings of the National Academy of Sciences of the United States of America. 103: 10397-402. PMID 16798876 DOI: 10.1073/Pnas.0604008103  0.48
2006 Centeno C, Repici M, Chatton JY, Riederer BM, Bonny C, Nicod P, Price M, Clarke PG, Papa S, Franzoso G, Borsello T. Role of the JNK pathway in NMDA-mediated excitotoxicity of cortical neurons. Cell Death and Differentiation. 14: 240-53. PMID 16794604 DOI: 10.1038/Sj.Cdd.4401988  0.373
2006 Papa S, Bubici C, Zazzeroni F, Pham CG, Kuntzen C, Knabb JR, Dean K, Franzoso G. The NF-kappaB-mediated control of the JNK cascade in the antagonism of programmed cell death in health and disease. Cell Death and Differentiation. 13: 712-29. PMID 16456579 DOI: 10.1038/Sj.Cdd.4401865  0.82
2006 Mittal A, Papa S, Franzoso G, Sen R. NF-kappaB-dependent regulation of the timing of activation-induced cell death of T lymphocytes. Journal of Immunology (Baltimore, Md. : 1950). 176: 2183-9. PMID 16455974 DOI: 10.4049/Jimmunol.176.4.2183  0.516
2006 Bubici C, Papa S, Pham CG, Zazzeroni F, Franzoso G. The NF-kappaB-mediated control of ROS and JNK signaling. Histology and Histopathology. 21: 69-80. PMID 16267788 DOI: 10.14670/Hh-21.69  0.83
2006 Lo JC, Basak S, James ES, Quiambo RS, Kinsella MC, Alegre ML, Weih F, Franzoso G, Hoffmann A, Fu YX. Coordination between NF-kappaB family members p50 and p52 is essential for mediating LTbetaR signals in the development and organization of secondary lymphoid tissues. Blood. 107: 1048-55. PMID 16195333 DOI: 10.1182/Blood-2005-06-2452  0.438
2006 Yang H, Bocchetta M, Kroczynska B, Elmishad A, Chen Y, Liu Z, Bubici C, Mossman B, Pass H, Testa J, Franzoso G, Carbone M. 87 TNF-α inhibits asbestos induced cytotoxicity via a NF-kB dependent pathway: A possible mechanism for asbestos-induced oncogenesis Lung Cancer. 54: S21. DOI: 10.1016/S0169-5002(07)70163-0  0.353
2005 Pham CG, Papa S, Bubici C, Zazzeroni F, Franzoso G. In the Crosshairs: NF-κB Targets the JNK Signaling Cascade. Current Medicinal Chemistry. Anti-Inflammatory & Anti-Allergy Agents. 4: 569-576. PMID 19829748 DOI: 10.2174/156801405774933188  0.827
2005 Papa S, Bubici C, Pham CG, Zazzeroni F, Franzoso G. NF-kappaB meets ROS: an 'iron-ic' encounter. Cell Death and Differentiation. 12: 1259-62. PMID 15947786 DOI: 10.1038/Sj.Cdd.4401694  0.739
2005 Pham CG, Papa S, Bubici C, Zazzeroni F, Franzoso G. Oxygen JNKies: phosphatases overdose on ROS. Developmental Cell. 8: 452-4. PMID 15809025 DOI: 10.1016/J.Devcel.2005.03.005  0.732
2004 Bubici C, Papa S, Pham CG, Zazzeroni F, Franzoso G. NF-kappaB and JNK: an intricate affair. Cell Cycle (Georgetown, Tex.). 3: 1524-9. PMID 15611622 DOI: 10.4161/Cc.3.12.1321  0.829
2004 Pham CG, Bubici C, Zazzeroni F, Papa S, Jones J, Alvarez K, Jayawardena S, De Smaele E, Cong R, Beaumont C, Torti FM, Torti SV, Franzoso G. Ferritin heavy chain upregulation by NF-kappaB inhibits TNFalpha-induced apoptosis by suppressing reactive oxygen species. Cell. 119: 529-42. PMID 15537542 DOI: 10.1016/J.Cell.2004.10.017  0.821
2004 Papa S, Zazzeroni F, Pham CG, Bubici C, Franzoso G. Linking JNK signaling to NF-kappaB: a key to survival. Journal of Cell Science. 117: 5197-208. PMID 15483317 DOI: 10.1242/Jcs.01483  0.81
2004 Barnhart BC, Legembre P, Pietras E, Bubici C, Franzoso G, Peter ME. CD95 ligand induces motility and invasiveness of apoptosis-resistant tumor cells. The Embo Journal. 23: 3175-85. PMID 15272306 DOI: 10.1038/Sj.Emboj.7600325  0.355
2004 Papa S, Zazzeroni F, Bubici C, Jayawardena S, Alvarez K, Matsuda S, Nguyen DU, Pham CG, Nelsbach AH, Melis T, De Smaele E, Tang WJ, D'Adamio L, Franzoso G. Gadd45 beta mediates the NF-kappa B suppression of JNK signalling by targeting MKK7/JNKK2. Nature Cell Biology. 6: 146-53. PMID 14743220 DOI: 10.1038/Ncb1093  0.782
2003 Lo JC, Chin RK, Lee Y, Kang HS, Wang Y, Weinstock JV, Banks T, Ware CF, Franzoso G, Fu YX. Differential regulation of CCL21 in lymphoid/nonlymphoid tissues for effectively attracting T cells to peripheral tissues. The Journal of Clinical Investigation. 112: 1495-505. PMID 14617751 DOI: 10.1172/Jci19188  0.35
2003 Liu N, Raja SM, Zazzeroni F, Metkar SS, Shah R, Zhang M, Wang Y, Brömme D, Russin WA, Lee JC, Peter ME, Froelich CJ, Franzoso G, Ashton-Rickardt PG. NF-kappaB protects from the lysosomal pathway of cell death. The Embo Journal. 22: 5313-22. PMID 14517268 DOI: 10.1093/Emboj/Cdg510  0.617
2003 Zazzeroni F, Papa S, Algeciras-Schimnich A, Alvarez K, Melis T, Bubici C, Majewski N, Hay N, De Smaele E, Peter ME, Franzoso G. Gadd45 beta mediates the protective effects of CD40 costimulation against Fas-induced apoptosis. Blood. 102: 3270-9. PMID 12855571 DOI: 10.1182/Blood-2003-03-0689  0.439
2003 Medici MA, Sciortino MT, Perri D, Amici C, Avitabile E, Ciotti M, Balestrieri E, De Smaele E, Franzoso G, Mastino A. Protection by herpes simplex virus glycoprotein D against Fas-mediated apoptosis: role of nuclear factor kappaB. The Journal of Biological Chemistry. 278: 36059-67. PMID 12844494 DOI: 10.1074/Jbc.M306198200  0.51
2003 Franzoso G, Zazzeroni F, Papa S. JNK: a killer on a transcriptional leash. Cell Death and Differentiation. 10: 13-5. PMID 12655290 DOI: 10.1038/Sj.Cdd.4401154  0.577
2003 Zazzeroni F, Papa S, Smaele ED, Franzoso G. Cell signalling (communication arising): Cell survival and a Gadd45-factor deficiency Nature. 424: 742. DOI: 10.1038/424742A  0.575
2002 Jin R, De Smaele E, Zazzeroni F, Nguyen DU, Papa S, Jones J, Cox C, Gelinas C, Franzoso G. Regulation of the gadd45beta promoter by NF-kappaB. Dna and Cell Biology. 21: 491-503. PMID 12162804 DOI: 10.1089/104454902320219059  0.641
2002 Guiet C, Silvestri E, Smaele ED, Franzoso G, Vito P. c-FLIP efficiently rescues TRAF-2-/- cells from TNF-induced apoptosis. Cell Death & Differentiation. 9: 138-144. PMID 11840164 DOI: 10.1038/Sj.Cdd.4400947  0.426
2001 Smaele ED, Zazzeroni F, Papa S, Nguyen DU, Jin R, Jones J, Cong R, Franzoso G. Induction of gadd45beta by NF-kappaB downregulates pro-apoptotic JNK signalling Nature. 414: 308-313. PMID 11713530 DOI: 10.1038/35104560  0.656
2000 Leonardi A, Ellinger-Ziegelbauer H, Franzoso G, Brown K, Siebenlist U. Physical and functional interaction of filamin (actin-binding protein-280) and tumor necrosis factor receptor-associated factor 2. Journal of Biological Chemistry. 275: 271-278. PMID 10617615 DOI: 10.1074/Jbc.275.1.271  0.551
1999 Boyce BF, Xing L, Franzoso G, Siebenlist U. Required and nonessential functions of nuclear factor-kappa B in bone cells. Bone. 25: 137-9. PMID 10423039 DOI: 10.1016/S8756-3282(99)00105-2  0.604
1999 Chariot A, Princen F, Gielen J, Merville M, Franzoso G, Brown K, Siebenlist U, Bours V. IkappaB-alpha enhances transactivation by the HOXB7 homeodomain-containing protein. Journal of Biological Chemistry. 274: 5318-5325. PMID 10026139 DOI: 10.1074/Jbc.274.9.5318  0.41
1998 Franzoso G, Carlson L, Poljak L, Shores EW, Epstein S, Leonardi A, Grinberg A, Tran T, Scharton-Kersten T, Anver M, Love P, Brown K, Siebenlist U. Mice deficient in nuclear factor (NF)-κB/p52 present with defects in humoral responses, germinal center reactions, and splenic microarchitecture Journal of Experimental Medicine. 187: 147-159. PMID 9432973 DOI: 10.1084/Jem.187.2.147  0.397
1997 Franzoso G, Carlson L, Xing L, Poljak L, Shores EW, Brown KD, Leonardi A, Tran T, Boyce BF, Siebenlist U. Requirement for NF-κB in osteoclast and B-cell development Genes and Development. 11: 3482-3496. PMID 9407039 DOI: 10.1101/Gad.11.24.3482  0.492
1997 Brown K, Franzoso G, Baldi L, Carlson L, Mills L, Lin YC, Gerstberger S, Siebenlist U. The signal response of IkappaB alpha is regulated by transferable N- and C-terminal domains. Molecular and Cellular Biology. 17: 3021-7. PMID 9154800 DOI: 10.1128/Mcb.17.6.3021  0.395
1997 Franzoso G, Carlson L, Scharton-Kersten T, Shores EW, Epstein S, Grinberg A, Tran T, Shacter E, Leonardi A, Anver M, Love P, Sher A, Siebenlist U. Critical roles for the Bcl-3 oncoprotein in T cell-mediated immunity, splenic microarchitecture, and germinal center reactions Immunity. 6: 479-490. PMID 9133427 DOI: 10.1016/S1074-7613(00)80291-5  0.33
1996 Ruocco MR, Chen X, Ambrosino C, Dragonetti E, Liu W, Mallardo M, De Falco G, Palmieri C, Franzoso G, Quinto I, Venuta S, Scala G. Regulation of HIV-1 long terminal repeats by interaction of C/EBP(NF-IL6) and NF-kappaB/Rel transcription factors. The Journal of Biological Chemistry. 271: 22479-86. PMID 8798413 DOI: 10.1074/Jbc.271.37.22479  0.408
1996 Baldi L, Brown K, Franzoso G, Siebenlist U. Critical role for lysines 21 and 22 in signal-induced, ubiquitin-mediated proteolysis of I kappa B-alpha. The Journal of Biological Chemistry. 271: 376-9. PMID 8550590 DOI: 10.1074/Jbc.271.1.376  0.476
1996 Franzoso G, Carlson L, Brown K, Daucher MB, Bressler P, Siebenlist U. Activation of the serum response factor by p65/NF-kappaB. The Embo Journal. 15: 3403-3412. DOI: 10.1002/J.1460-2075.1996.Tb00706.X  0.44
1995 Drew PD, Franzoso G, Becker KG, Bours V, Carlson LM, Siebenlist U, Ozato K. NF kappa B and interferon regulatory factor 1 physically interact and synergistically induce major histocompatibility class I gene expression. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 15: 1037-45. PMID 8746784 DOI: 10.1089/Jir.1995.15.1037  0.457
1995 Drew PD, Franzoso G, Carlson LM, Biddison WE, Siebenlist U, Ozato K. Interferon regulatory factor-2 physically interacts with NF-kappa B in vitro and inhibits NF-kappa B induction of major histocompatibility class I and beta 2-microglobulin gene expression in transfected human neuroblastoma cells. Journal of Neuroimmunology. 63: 157-62. PMID 8550813 DOI: 10.1016/0165-5728(95)00140-9  0.457
1995 Siebenlist U, Franzoso G, Brown K. Structure, regulation and function of NF-kappa B. Annual Review of Cell Biology. 10: 405-55. PMID 7888182 DOI: 10.1146/Annurev.Cb.10.110194.002201  0.433
1995 Brown K, Gerstberger S, Carlson L, Franzoso G, Siebenlist U. Control of I kappa B-alpha proteolysis by site-specific, signal-induced phosphorylation. Science (New York, N.Y.). 267: 1485-8. PMID 7878466 DOI: 10.1126/Science.7878466  0.471
1995 Kanno T, Franzoso G, Siebenlist U. Human T-cell leukemia virus type I Tax-protein-mediated activation of NF-kappa B from p100 (NF-kappa B2)-inhibited cytoplasmic reservoirs. Proceedings of the National Academy of Sciences of the United States of America. 91: 12634-8. PMID 7809091 DOI: 10.1073/Pnas.91.26.12634  0.487
1994 Kanno T, Brown K, Franzoso G, Siebenlist U. Kinetic analysis of human T-cell leukemia virus type I Tax-mediated activation of NF-kappa B. Molecular and Cellular Biology. 14: 6443-51. PMID 7935369 DOI: 10.1128/Mcb.14.10.6443  0.519
1994 Franzoso G, Biswas P, Poli G, Carlson LM, Brown KD, Tomita-Yamaguchi M, Fauci AS, Siebenlist UK. A family of serine proteases expressed exclusively in myelo-monocytic cells specifically processes the nuclear factor-kappa B subunit p65 in vitro and may impair human immunodeficiency virus replication in these cells. The Journal of Experimental Medicine. 180: 1445-56. PMID 7931077 DOI: 10.1084/Jem.180.4.1445  0.36
1993 Brown K, Park S, Kanno T, Franzoso G, Siebenlist U. Mutual regulation of the transcriptional activator NF-kappa B and its inhibitor, I kappa B-alpha. Proceedings of the National Academy of Sciences of the United States of America. 90: 2532-6. PMID 8460169 DOI: 10.1073/Pnas.90.6.2532  0.443
1993 Bours V, Franzoso G, Azarenko V, Park S, Kanno T, Brown K, Siebenlist U. The oncoprotein Bcl-3 directly transactivates through κB motifs via association with DNA-binding p50B homodimers Cell. 72: 729-739. PMID 8453667 DOI: 10.1016/0092-8674(93)90401-B  0.388
1993 Segars JH, Nagata T, Bours V, Medin JA, Franzoso G, Blanco JCG, Drew PD, Becker KG, An J, Tang T, Stephany DA, Neel B, Siebenlist U, Ozato K. Retinoic acid induction of major histocompatibility complex class I genes in NTera-2 embryonal carcinoma cells involves induction of NF-κB (p50-p65) and retinoic acid receptor β-retinoid X receptor β heterodimers Molecular and Cellular Biology. 13: 6157-6169. PMID 8413217 DOI: 10.1128/Mcb.13.10.6157  0.366
1993 Bours V, Franzoso G, Brown K, Park S, Azarenko V, Tomita-Yamaguchi M, Kelly K, Siebenlist U. Lymphocyte activation and the family of NF-kappa B transcription factor complexes. Current Topics in Microbiology and Immunology. 182: 411-20. PMID 1490379 DOI: 10.1007/978-3-642-77633-5_52  0.577
1993 Franzoso G, Bours V, Azarenko V, Park S, Tomita-Yamaguchi M, Kanno T, Brown K, Siebenlist U. The oncoprotein Bcl-3 can facilitate NF-kappa B-mediated transactivation by removing inhibiting p50 homodimers from select kappa B sites. The Embo Journal. 12: 3893-3901. DOI: 10.1002/J.1460-2075.1993.Tb06067.X  0.432
1992 Franzoso G, Bours V, Park S, Tomita-Yamaguchi M, Kelly K, Siebenlist U. The candidate oncoprotein Bcl-3 is an antagonist of p50/NF-kappa B-mediated inhibition. Nature. 359: 339-342. PMID 1406939 DOI: 10.1038/359339A0  0.582
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