Konrad Basler - Publications


165 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Zimmerli D, Borrelli C, Jauregi-Miguel A, Söderholm S, Brütsch S, Doumpas N, Reichmuth J, Murphy-Seiler F, Aguet M, Basler K, Moor AE, Cantù C. TBX3 acts as tissue-specific component of the Wnt/β-catenin transcriptional complex. Elife. 9. PMID 32808927 DOI: 10.7554/Elife.58123  0.52
2020 Zimmerli D, Borrelli C, Jauregi-Miguel A, Söderholm S, Brütsch S, Doumpas N, Reichmuth J, Murphy-Seiler F, Aguet M, Basler K, Moor AE, Cantù C. Author response: TBX3 acts as tissue-specific component of the Wnt/β-catenin transcriptional complex Elife. DOI: 10.7554/Elife.58123.Sa2  0.52
2019 Brunner E, Yagi R, Debrunner M, Beck-Schneider D, Burger A, Escher E, Mosimann C, Hausmann G, Basler K. CRISPR-induced double-strand breaks trigger recombination between homologous chromosome arms. Life Science Alliance. 2. PMID 31196871 DOI: 10.26508/lsa.201800267  0.48
2018 Germani F, Hain D, Sternlicht D, Moreno E, Basler K. The Toll pathway inhibits tissue growth and regulates cell fitness in an infection-dependent manner. Elife. 7. PMID 30451683 DOI: 10.7554/eLife.39939  1
2018 Cantù C, Felker A, Zimmerli D, Prummel KD, Cabello EM, Chiavacci E, Méndez-Acevedo KM, Kirchgeorg L, Burger S, Ripoll J, Valenta T, Hausmann G, Vilain N, Aguet M, Burger A, ... ... Basler K, et al. Mutations in and genes cause congenital heart defects by tissue-specific perturbation of Wnt/β-catenin signaling. Genes & Development. PMID 30366904 DOI: 10.1101/Gad.315531.118  0.52
2018 Spletter ML, Barz C, Yeroslaviz A, Zhang X, Lemke SB, Bonnard A, Brunner E, Cardone G, Basler K, Habermann BH, Schnorrer F. A transcriptomics resource reveals a transcriptional transition during ordered sarcomere morphogenesis in flight muscle. Elife. 7. PMID 29846170 DOI: 10.7554/Elife.34058  0.48
2018 Germani F, Hain D, Sternlicht D, Moreno E, Basler K. Author response: The Toll pathway inhibits tissue growth and regulates cell fitness in an infection-dependent manner Elife. DOI: 10.7554/Elife.39939.019  1
2018 Spletter ML, Barz C, Yeroslaviz A, Zhang X, Lemke SB, Bonnard A, Brunner E, Cardone G, Basler K, Habermann BH, Schnorrer F. Author response: A transcriptomics resource reveals a transcriptional transition during ordered sarcomere morphogenesis in flight muscle Elife. DOI: 10.7554/Elife.34058.052  0.48
2017 Eder D, Basler K, Aegerter CM. Challenging FRET-based E-Cadherin force measurements in Drosophila. Scientific Reports. 7: 13692. PMID 29057959 DOI: 10.1038/s41598-017-14136-y  0.4
2017 Franz A, Brunner E, Basler K. Generation of genome-modified Drosophila cell lines using SwAP. Fly. 0. PMID 28853976 DOI: 10.1080/19336934.2017.1372068  0.48
2017 Marty F, Rago G, Smith DF, Gao X, Eijkel GB, MacAleese L, Bonn M, Brunner E, Basler K, Heeren RMA. Combining ToF-SIMS imaging mass spectrometry and CARS microspectroscopy reveals lipid patterns reminiscent of gene expression patterns in the wing imaginal disc of Drosophila melanogaster. Analytical Chemistry. PMID 28727418 DOI: 10.1021/Acs.Analchem.7B00125  0.48
2017 Franz A, Shlyueva D, Brunner E, Stark A, Basler K. Probing the canonicity of the Wnt/wingless signaling pathway. Plos Genetics. 13: e1006700. PMID 28369070 DOI: 10.1371/journal.pgen.1006700  0.48
2016 Restrepo S, Zartman JJ, Basler K. Cultivation and Live Imaging of Drosophila Imaginal Discs. Methods in Molecular Biology (Clifton, N.J.). 1478: 203-213. PMID 27730583 DOI: 10.1007/978-1-4939-6371-3_11  0.52
2016 Restrepo S, Basler K. Drosophila wing imaginal discs respond to mechanical injury via slow InsP3R-mediated intercellular calcium waves. Nature Communications. 7: 12450. PMID 27503836 DOI: 10.1038/ncomms12450  0.52
2016 Valenta T, Degirmenci B, Moor AE, Herr P, Zimmerli D, Moor MB, Hausmann G, Cantù C, Aguet M, Basler K. Wnt Ligands Secreted by Subepithelial Mesenchymal Cells Are Essential for the Survival of Intestinal Stem Cells and Gut Homeostasis. Cell Reports. PMID 27117411 DOI: 10.1016/J.Celrep.2016.03.088  0.52
2016 Heller D, Hoppe A, Restrepo S, Gatti L, Tournier AL, Tapon N, Basler K, Mao Y. EpiTools: An Open-Source Image Analysis Toolkit for Quantifying Epithelial Growth Dynamics. Developmental Cell. 36: 103-16. PMID 26766446 DOI: 10.1016/J.Devcel.2015.12.012  1
2015 Moor AE, Anderle P, Cantù C, Rodriguez P, Wiedemann N, Baruthio F, Deka J, André S, Valenta T, Moor MB, Győrffy B, Barras D, Delorenzi M, Basler K, Aguet M. BCL9/9L-β-catenin Signaling is Associated With Poor Outcome in Colorectal Cancer. Ebiomedicine. 2: 1932-43. PMID 26844272 DOI: 10.1016/J.Ebiom.2015.10.030  0.52
2015 Zemke M, Draganova K, Klug A, Schöler A, Zurkirchen L, Gay MH, Cheng P, Koseki H, Valenta T, Schübeler D, Basler K, Sommer L. Loss of Ezh2 promotes a midbrain-to-forebrain identity switch by direct gene derepression and Wnt-dependent regulation. Bmc Biology. 13: 103. PMID 26621269 DOI: 10.1186/S12915-015-0210-9  1
2015 Barbier de Reuille P, Routier-Kierzkowska AL, Kierzkowski D, Bassel GW, Schüpbach T, Tauriello G, Bajpai N, Strauss S, Weber A, Kiss A, Burian A, Hofhuis H, Sapala A, Lipowczan M, Heimlicher MB, ... ... Basler K, et al. MorphoGraphX: A platform for quantifying morphogenesis in 4D. Elife. 4: 05864. PMID 25946108 DOI: 10.7554/Elife.05864  1
2015 Gay MH, Valenta T, Herr P, Paratore-Hari L, Basler K, Sommer L. Distinct adhesion-independent functions of β-catenin control stage-specific sensory neurogenesis and proliferation. Bmc Biology. 13: 24. PMID 25885041 DOI: 10.1186/s12915-015-0134-4  1
2015 Andersen DS, Colombani J, Palmerini V, Chakrabandhu K, Boone E, Röthlisberger M, Toggweiler J, Basler K, Mapelli M, Hueber AO, Léopold P. The Drosophila TNF receptor Grindelwald couples loss of cell polarity and neoplastic growth. Nature. 522: 482-6. PMID 25874673 DOI: 10.1038/nature14298  1
2015 Gillers BS, Chiplunkar A, Aly H, Valenta T, Basler K, Christoffels VM, Efimov IR, Boukens BJ, Rentschler S. Canonical wnt signaling regulates atrioventricular junction programming and electrophysiological properties. Circulation Research. 116: 398-406. PMID 25599332 DOI: 10.1161/Circresaha.116.304731  1
2015 Schertel C, Albarca M, Rockel-Bauer C, Kelley NW, Bischof J, Hens K, van Nimwegen E, Basler K, Deplancke B. A large-scale, in vivo transcription factor screen defines bivalent chromatin as a key property of regulatory factors mediating Drosophila wing development. Genome Research. 25: 514-23. PMID 25568052 DOI: 10.1101/Gr.181305.114  1
2015 Lebert D, Louwagie M, Goetze S, Picard G, Ossola R, Duquesne C, Basler K, Ferro M, Rinner O, Aebersold R, Garin J, Mouz N, Brunner E, Brun V. DIGESTIF: a universal quality standard for the control of bottom-up proteomics experiments. Journal of Proteome Research. 14: 787-803. PMID 25495225 DOI: 10.1021/Pr500834Z  1
2015 Draganova K, Zemke M, Zurkirchen L, Valenta T, Cantù C, Okoniewski M, Schmid MT, Hoffmans R, Götz M, Basler K, Sommer L. Wnt/β-catenin signaling regulates sequential fate decisions of murine cortical precursor cells. Stem Cells (Dayton, Ohio). 33: 170-82. PMID 25182747 DOI: 10.1002/Stem.1820  1
2015 Reuille PBd, Routier-Kierzkowska A, Kierzkowski D, Bassel GW, Schüpbach T, Tauriello G, Bajpai N, Strauss S, Weber A, Kiss A, Burian A, Hofhuis H, Sapala A, Lipowczan M, Heimlicher MB, ... ... Basler K, et al. Author response: MorphoGraphX: A platform for quantifying morphogenesis in 4D Elife. DOI: 10.7554/Elife.05864.024  0.4
2014 Jenny FH, Basler K. Powerful Drosophila screens that paved the wingless pathway. Fly. 8: 218-25. PMID 25565425 DOI: 10.4161/19336934.2014.985988  1
2014 Meyer SN, Amoyel M, Bergantiños C, de la Cova C, Schertel C, Basler K, Johnston LA. An ancient defense system eliminates unfit cells from developing tissues during cell competition. Science (New York, N.Y.). 346: 1258236. PMID 25477468 DOI: 10.1126/Science.1258236  1
2014 Reim G, Hruzova M, Goetze S, Basler K. Protection of armadillo/β-Catenin by armless, a novel positive regulator of wingless signaling. Plos Biology. 12: e1001988. PMID 25369031 DOI: 10.1371/journal.pbio.1001988  1
2014 Cantù C, Zimmerli D, Hausmann G, Valenta T, Moor A, Aguet M, Basler K. Pax6-dependent, but β-catenin-independent, function of Bcl9 proteins in mouse lens development. Genes & Development. 28: 1879-84. PMID 25184676 DOI: 10.1101/Gad.246140.114  1
2014 Bischof J, Sheils EM, Björklund M, Basler K. Generation of a transgenic ORFeome library in Drosophila. Nature Protocols. 9: 1607-20. PMID 24922270 DOI: 10.1038/nprot.2014.105  1
2014 Schilling S, Steiner S, Zimmerli D, Basler K. A regulatory receptor network directs the range and output of the Wingless signal. Development (Cambridge, England). 141: 2483-93. PMID 24917503 DOI: 10.1242/dev.108662  1
2014 Qeli E, Omasits U, Goetze S, Stekhoven DJ, Frey JE, Basler K, Wollscheid B, Brunner E, Ahrens CH. Improved prediction of peptide detectability for targeted proteomics using a rank-based algorithm and organism-specific data. Journal of Proteomics. 108: 269-83. PMID 24878426 DOI: 10.1016/j.jprot.2014.05.011  1
2014 Baillon L, Basler K. Reflections on cell competition. Seminars in Cell & Developmental Biology. 32: 137-44. PMID 24811317 DOI: 10.1016/j.semcdb.2014.04.034  1
2014 Marty F, Rockel-Bauer C, Simigdala N, Brunner E, Basler K. Large-scale imaginal disc sorting: A protocol for "omics"-approaches. Methods (San Diego, Calif.). 68: 260-4. PMID 24736056 DOI: 10.1016/j.ymeth.2014.04.005  1
2014 Restrepo S, Zartman JJ, Basler K. Coordination of patterning and growth by the morphogen DPP. Current Biology : Cb. 24: R245-55. PMID 24650915 DOI: 10.1016/J.Cub.2014.01.055  1
2013 Gerber F, Marty F, Eijkel GB, Basler K, Brunner E, Furrer R, Heeren RM. Multiorder correction algorithms to remove image distortions from mass spectrometry imaging data sets. Analytical Chemistry. 85: 10249-54. PMID 24093946 DOI: 10.1021/Ac402018E  1
2013 Gafner L, Dalessi S, Escher E, Pyrowolakis G, Bergmann S, Basler K. Manipulating the sensitivity of signal-induced repression: quantification and consequences of altered brinker gradients. Plos One. 8: e71224. PMID 23951114 DOI: 10.1371/journal.pone.0071224  1
2013 Pepperl J, Reim G, Lüthi U, Kaech A, Hausmann G, Basler K. Sphingolipid depletion impairs endocytic traffic and inhibits Wingless signaling. Mechanisms of Development. 130: 493-505. PMID 23665457 DOI: 10.1016/j.mod.2013.04.001  1
2013 Cantù C, Valenta T, Hausmann G, Vilain N, Aguet M, Basler K. The Pygo2-H3K4me2/3 interaction is dispensable for mouse development and Wnt signaling-dependent transcription. Development (Cambridge, England). 140: 2377-86. PMID 23637336 DOI: 10.1242/Dev.093591  1
2013 Bischof J, Björklund M, Furger E, Schertel C, Taipale J, Basler K. A versatile platform for creating a comprehensive UAS-ORFeome library in Drosophila. Development (Cambridge, England). 140: 2434-42. PMID 23637332 DOI: 10.1242/dev.088757  1
2013 Schertel C, Huang D, Björklund M, Bischof J, Yin D, Li R, Wu Y, Zeng R, Wu J, Taipale J, Song H, Basler K. Systematic screening of a Drosophila ORF library in vivo uncovers Wnt/Wg pathway components. Developmental Cell. 25: 207-19. PMID 23583758 DOI: 10.1016/J.Devcel.2013.02.019  1
2013 Cantù C, Valenta T, Basler K. A RING finger to wed TCF and β-catenin. Embo Reports. 14: 295-6. PMID 23478335 DOI: 10.1038/embor.2013.21  1
2013 Zartman J, Restrepo S, Basler K. A high-throughput template for optimizing Drosophila organ culture with response-surface methods. Development (Cambridge, England). 140: 667-74. PMID 23293298 DOI: 10.1242/Dev.088872  1
2012 Hödl M, Basler K. Transcription in the absence of histone H3.2 and H3K4 methylation. Current Biology : Cb. 22: 2253-7. PMID 23142044 DOI: 10.1016/j.cub.2012.10.008  1
2012 Schertel C, Rutishauser T, Förstemann K, Basler K. Functional characterization of Drosophila microRNAs by a novel in vivo library. Genetics. 192: 1543-52. PMID 23051640 DOI: 10.1534/genetics.112.145383  1
2012 Aegerter-Wilmsen T, Heimlicher MB, Smith AC, de Reuille PB, Smith RS, Aegerter CM, Basler K. Integrating force-sensing and signaling pathways in a model for the regulation of wing imaginal disc size. Development (Cambridge, England). 139: 3221-31. PMID 22833127 DOI: 10.1242/dev.082800  1
2012 Herr P, Hausmann G, Basler K. WNT secretion and signalling in human disease. Trends in Molecular Medicine. 18: 483-93. PMID 22796206 DOI: 10.1016/j.molmed.2012.06.008  1
2012 Valenta T, Hausmann G, Basler K. The many faces and functions of β-catenin. The Embo Journal. 31: 2714-36. PMID 22617422 DOI: 10.1038/emboj.2012.150  1
2012 Schwank G, Yang SF, Restrepo S, Basler K. Comment on "Dynamics of dpp signaling and proliferation control". Science (New York, N.Y.). 335: 401; author reply 40. PMID 22282789 DOI: 10.1126/science.1210997  1
2012 Herr P, Basler K. Porcupine-mediated lipidation is required for Wnt recognition by Wls. Developmental Biology. 361: 392-402. PMID 22108505 DOI: 10.1016/j.ydbio.2011.11.003  1
2011 Valenta T, Gay M, Steiner S, Draganova K, Zemke M, Hoffmans R, Cinelli P, Aguet M, Sommer L, Basler K. Probing transcription-specific outputs of β-catenin in vivo. Genes & Development. 25: 2631-43. PMID 22190459 DOI: 10.1101/Gad.181289.111  1
2011 Gasnereau I, Herr P, Chia PZ, Basler K, Gleeson PA. Identification of an endocytosis motif in an intracellular loop of Wntless protein, essential for its recycling and the control of Wnt protein signaling. The Journal of Biological Chemistry. 286: 43324-33. PMID 22027831 DOI: 10.1074/jbc.M111.307231  1
2011 Restrepo S, Basler K. Morphogen gradients: expand and repress. Current Biology : Cb. 21: R815-7. PMID 21996505 DOI: 10.1016/j.cub.2011.08.041  1
2011 Port F, Hausmann G, Basler K. A genome-wide RNA interference screen uncovers two p24 proteins as regulators of Wingless secretion. Embo Reports. 12: 1144-52. PMID 21886182 DOI: 10.1038/embor.2011.165  1
2011 Schwank G, Dalessi S, Yang SF, Yagi R, de Lachapelle AM, Affolter M, Bergmann S, Basler K. Formation of the long range Dpp morphogen gradient. Plos Biology. 9: e1001111. PMID 21814489 DOI: 10.1371/journal.pbio.1001111  1
2011 Harterink M, Port F, Lorenowicz MJ, McGough IJ, Silhankova M, Betist MC, van Weering JR, van Heesbeen RG, Middelkoop TC, Basler K, Cullen PJ, Korswagen HC. A SNX3-dependent retromer pathway mediates retrograde transport of the Wnt sorting receptor Wntless and is required for Wnt secretion. Nature Cell Biology. 13: 914-23. PMID 21725319 DOI: 10.1038/ncb2281  1
2011 Willecke M, Toggweiler J, Basler K. Loss of PI3K blocks cell-cycle progression in a Drosophila tumor model. Oncogene. 30: 4067-74. PMID 21516128 DOI: 10.1038/onc.2011.125  1
2011 Affolter M, Basler K. Cell biology. Cytonemes show their colors. Science (New York, N.Y.). 332: 312-3. PMID 21493848 DOI: 10.1126/science.1205971  1
2011 Schilling S, Willecke M, Aegerter-Wilmsen T, Cirpka OA, Basler K, von Mering C. Cell-sorting at the A/P boundary in the Drosophila wing primordium: a computational model to consolidate observed non-local effects of Hh signaling. Plos Computational Biology. 7: e1002025. PMID 21490725 DOI: 10.1371/journal.pcbi.1002025  1
2011 Schwank G, Tauriello G, Yagi R, Kranz E, Koumoutsakos P, Basler K. Antagonistic growth regulation by Dpp and Fat drives uniform cell proliferation. Developmental Cell. 20: 123-30. PMID 21238930 DOI: 10.1016/J.Devcel.2010.11.007  1
2010 Silhankova M, Port F, Harterink M, Basler K, Korswagen HC. Wnt signalling requires MTM-6 and MTM-9 myotubularin lipid-phosphatase function in Wnt-producing cells. The Embo Journal. 29: 4094-105. PMID 21076391 DOI: 10.1038/emboj.2010.278  1
2010 Ahrens CH, Brunner E, Qeli E, Basler K, Aebersold R. Generating and navigating proteome maps using mass spectrometry. Nature Reviews. Molecular Cell Biology. 11: 789-801. PMID 20944666 DOI: 10.1038/Nrm2973  1
2010 Yagi R, Mayer F, Basler K. Refined LexA transactivators and their use in combination with the Drosophila Gal4 system. Proceedings of the National Academy of Sciences of the United States of America. 107: 16166-71. PMID 20805468 DOI: 10.1073/pnas.1005957107  1
2010 Deka J, Wiedemann N, Anderle P, Murphy-Seiler F, Bultinck J, Eyckerman S, Stehle JC, André S, Vilain N, Zilian O, Robine S, Delorenzi M, Basler K, Aguet M. Bcl9/Bcl9l are critical for Wnt-mediated regulation of stem cell traits in colon epithelium and adenocarcinomas. Cancer Research. 70: 6619-28. PMID 20682801 DOI: 10.1158/0008-5472.Can-10-0148  1
2010 Port F, Basler K. Wnt trafficking: new insights into Wnt maturation, secretion and spreading. Traffic (Copenhagen, Denmark). 11: 1265-71. PMID 20477987 DOI: 10.1111/j.1600-0854.2010.01076.x  1
2010 Song H, Goetze S, Bischof J, Spichiger-Haeusermann C, Kuster M, Brunner E, Basler K. Coop functions as a corepressor of Pangolin and antagonizes Wingless signaling. Genes & Development. 24: 881-6. PMID 20439429 DOI: 10.1101/Gad.561310  1
2010 Schwank G, Basler K. Regulation of organ growth by morphogen gradients. Cold Spring Harbor Perspectives in Biology. 2: a001669. PMID 20182606 DOI: 10.1101/cshperspect.a001669  1
2010 Aegerter-Wilmsen T, Smith AC, Christen AJ, Aegerter CM, Hafen E, Basler K. Exploring the effects of mechanical feedback on epithelial topology. Development (Cambridge, England). 137: 499-506. PMID 20081194 DOI: 10.1242/Dev.041731  1
2010 Ahrens CH, Brunner E, Basler K. Quantitative proteomics: a central technology for systems biology. Journal of Proteomics. 73: 820-7. PMID 20026292 DOI: 10.1016/j.jprot.2009.12.007  1
2009 Geuking P, Narasimamurthy R, Lemaitre B, Basler K, Leulier F. A non-redundant role for Drosophila Mkk4 and hemipterous/Mkk7 in TAK1-mediated activation of JNK. Plos One. 4: e7709. PMID 19888449 DOI: 10.1371/journal.pone.0007709  1
2009 Goetze S, Qeli E, Mosimann C, Staes A, Gerrits B, Roschitzki B, Mohanty S, Niederer EM, Laczko E, Timmerman E, Lange V, Hafen E, Aebersold R, Vandekerckhove J, Basler K, et al. Identification and functional characterization of N-terminally acetylated proteins in Drosophila melanogaster. Plos Biology. 7: e1000236. PMID 19885390 DOI: 10.1371/Journal.Pbio.1000236  1
2009 Hamaratoglu F, Basler K, Affolter M. Confronting morphogen gradients: how important are they for growth? Science Signaling. 2: pe67. PMID 19861687 DOI: 10.1126/Scisignal.294Pe67  1
2009 Song H, Spichiger-Haeusermann C, Basler K. The ISWI-containing NURF complex regulates the output of the canonical Wingless pathway. Embo Reports. 10: 1140-6. PMID 19713963 DOI: 10.1038/Embor.2009.157  1
2009 Hausmann G, von Mering C, Basler K. The hedgehog signaling pathway: where did it come from? Plos Biology. 7: e1000146. PMID 19564910 DOI: 10.1371/journal.pbio.1000146  1
2009 Grobei MA, Qeli E, Brunner E, Rehrauer H, Zhang R, Roschitzki B, Basler K, Ahrens CH, Grossniklaus U. Deterministic protein inference for shotgun proteomics data provides new insights into Arabidopsis pollen development and function. Genome Research. 19: 1786-800. PMID 19546170 DOI: 10.1101/Gr.089060.108  1
2009 Hödl M, Basler K. Transcription in the absence of histone H3.3. Current Biology : Cb. 19: 1221-6. PMID 19523831 DOI: 10.1016/j.cub.2009.05.048  1
2009 Kessler R, Hausmann G, Basler K. The PHD domain is required to link Drosophila Pygopus to Legless/beta-catenin and not to histone H3. Mechanisms of Development. 126: 752-9. PMID 19493659 DOI: 10.1016/j.mod.2009.04.003  1
2009 Mosimann C, Hausmann G, Basler K. The role of Parafibromin/Hyrax as a nuclear Gli/Ci-interacting protein in Hedgehog target gene control. Mechanisms of Development. 126: 394-405. PMID 19368795 DOI: 10.1016/j.mod.2009.02.002  1
2009 Mosimann C, Hausmann G, Basler K. Beta-catenin hits chromatin: regulation of Wnt target gene activation. Nature Reviews. Molecular Cell Biology. 10: 276-86. PMID 19305417 DOI: 10.1038/nrm2654  1
2009 Narasimamurthy R, Geuking P, Ingold K, Willen L, Schneider P, Basler K. Structure-function analysis of Eiger, the Drosophila TNF homolog. Cell Research. 19: 392-4. PMID 19223855 DOI: 10.1038/cr.2009.16  1
2008 Schwank G, Restrepo S, Basler K. Growth regulation by Dpp: an essential role for Brinker and a non-essential role for graded signaling levels. Development (Cambridge, England). 135: 4003-13. PMID 19029041 DOI: 10.1242/dev.025635  1
2008 Bischof J, Basler K. Recombinases and their use in gene activation, gene inactivation, and transgenesis. Methods in Molecular Biology (Clifton, N.J.). 420: 175-95. PMID 18641947 DOI: 10.1007/978-1-59745-583-1_10  1
2008 Affolter M, Pyrowolakis G, Weiss A, Basler K. Signal-induced repression: the exception or the rule in developmental signaling? Developmental Cell. 15: 11-22. PMID 18606137 DOI: 10.1016/j.devcel.2008.06.006  1
2008 Katanaev VL, Solis GP, Hausmann G, Buestorf S, Katanayeva N, Schrock Y, Stuermer CA, Basler K. Reggie-1/flotillin-2 promotes secretion of the long-range signalling forms of Wingless and Hedgehog in Drosophila. The Embo Journal. 27: 509-21. PMID 18219274 DOI: 10.1038/Sj.Emboj.7601981  1
2008 Port F, Kuster M, Herr P, Furger E, Bänziger C, Hausmann G, Basler K. Wingless secretion promotes and requires retromer-dependent cycling of Wntless. Nature Cell Biology. 10: 178-85. PMID 18193032 DOI: 10.1038/ncb1687  1
2007 Ahrens CH, Brunner E, Hafen E, Aebersold R, Basler K. A proteome catalog of Drosophila melanogaster: an essential resource for targeted quantitative proteomics. Fly. 1: 182-6. PMID 18820430 DOI: 10.4161/Fly.4532  1
2007 Affolter M, Basler K. The Decapentaplegic morphogen gradient: from pattern formation to growth regulation. Nature Reviews. Genetics. 8: 663-74. PMID 17703237 DOI: 10.1038/nrg2166  1
2007 Bischof J, Maeda RK, Hediger M, Karch F, Basler K. An optimized transgenesis system for Drosophila using germ-line-specific phiC31 integrases. Proceedings of the National Academy of Sciences of the United States of America. 104: 3312-7. PMID 17360644 DOI: 10.1073/pnas.0611511104  1
2007 Hausmann G, Bänziger C, Basler K. Helping Wingless take flight: how WNT proteins are secreted. Nature Reviews. Molecular Cell Biology. 8: 331-6. PMID 17342185 DOI: 10.1038/nrm2141  1
2007 Aegerter-Wilmsen T, Aegerter CM, Hafen E, Basler K. Model for the regulation of size in the wing imaginal disc of Drosophila. Mechanisms of Development. 124: 318-26. PMID 17293093 DOI: 10.1016/J.Mod.2006.12.005  1
2007 Hoffmans R, Basler K. BCL9-2 binds Arm/beta-catenin in a Tyr142-independent manner and requires Pygopus for its function in Wg/Wnt signaling. Mechanisms of Development. 124: 59-67. PMID 17113272 DOI: 10.1016/j.mod.2006.09.006  1
2006 Hausmann G, Basler K. Wnt lipid modifications: not as saturated as we thought. Developmental Cell. 11: 751-2. PMID 17141148 DOI: 10.1016/j.devcel.2006.11.007  1
2006 Städeli R, Hoffmans R, Basler K. Transcription under the control of nuclear Arm/beta-catenin. Current Biology : Cb. 16: R378-85. PMID 16713950 DOI: 10.1016/j.cub.2006.04.019  1
2006 Bänziger C, Soldini D, Schütt C, Zipperlen P, Hausmann G, Basler K. Wntless, a conserved membrane protein dedicated to the secretion of Wnt proteins from signaling cells. Cell. 125: 509-22. PMID 16678095 DOI: 10.1016/j.cell.2006.02.049  1
2006 Mosimann C, Hausmann G, Basler K. Parafibromin/Hyrax activates Wnt/Wg target gene transcription by direct association with beta-catenin/Armadillo. Cell. 125: 327-41. PMID 16630820 DOI: 10.1016/j.cell.2006.01.053  1
2005 Städeli R, Basler K. Dissecting nuclear Wingless signalling: recruitment of the transcriptional co-activator Pygopus by a chain of adaptor proteins. Mechanisms of Development. 122: 1171-82. PMID 16169192 DOI: 10.1016/j.mod.2005.07.004  1
2005 Geuking P, Narasimamurthy R, Basler K. A genetic screen targeting the tumor necrosis factor/Eiger signaling pathway: identification of Drosophila TAB2 as a functionally conserved component. Genetics. 171: 1683-94. PMID 16079232 DOI: 10.1534/genetics.105.045534  1
2005 Hoffmans R, Städeli R, Basler K. Pygopus and legless provide essential transcriptional coactivator functions to armadillo/beta-catenin. Current Biology : Cb. 15: 1207-11. PMID 16005293 DOI: 10.1016/j.cub.2005.05.054  1
2005 Zipperlen P, Nairz K, Rimann I, Basler K, Hafen E, Hengartner M, Hajnal A. A universal method for automated gene mapping. Genome Biology. 6: R19. PMID 15693948 DOI: 10.1186/Gb-2005-6-2-R19  1
2004 Nairz K, Zipperlen P, Dearolf C, Basler K, Hafen E. A reverse genetic screen in Drosophila using a deletion-inducing mutagen. Genome Biology. 5: R83. PMID 15461801 DOI: 10.1186/Gb-2004-5-10-R83  1
2004 Pyrowolakis G, Hartmann B, Müller B, Basler K, Affolter M. A simple molecular complex mediates widespread BMP-induced repression during Drosophila development. Developmental Cell. 7: 229-40. PMID 15296719 DOI: 10.1016/j.devcel.2004.07.008  1
2004 Hoffmans R, Basler K. Identification and in vivo role of the Armadillo-Legless interaction. Development (Cambridge, England). 131: 4393-400. PMID 15294866 DOI: 10.1242/dev.01296  1
2004 Moreno E, Basler K. dMyc transforms cells into super-competitors. Cell. 117: 117-29. PMID 15066287 DOI: 10.1016/S0092-8674(04)00262-4  1
2003 Schweizer L, Nellen D, Basler K. Requirement for Pangolin/dTCF in Drosophila Wingless signaling. Proceedings of the National Academy of Sciences of the United States of America. 100: 5846-51. PMID 12730381 DOI: 10.1073/pnas.1037533100  1
2003 Müller B, Hartmann B, Pyrowolakis G, Affolter M, Basler K. Conversion of an extracellular Dpp/BMP morphogen gradient into an inverse transcriptional gradient. Cell. 113: 221-33. PMID 12705870 DOI: 10.1016/S0092-8674(03)00241-1  1
2003 Végh M, Basler K. A genetic screen for hedgehog targets involved in the maintenance of the Drosophila anteroposterior compartment boundary. Genetics. 163: 1427-38. PMID 12702686  1
2002 Ma Y, Erkner A, Gong R, Yao S, Taipale J, Basler K, Beachy PA. Hedgehog-mediated patterning of the mammalian embryo requires transporter-like function of dispatched. Cell. 111: 63-75. PMID 12372301 DOI: 10.1016/S0092-8674(02)00977-7  1
2002 Moreno E, Yan M, Basler K. Evolution of TNF signaling mechanisms: JNK-dependent apoptosis triggered by Eiger, the Drosophila homolog of the TNF superfamily. Current Biology : Cb. 12: 1263-8. PMID 12176339 DOI: 10.1016/S0960-9822(02)00954-5  1
2002 Gerlitz O, Basler K. Wingful, an extracellular feedback inhibitor of Wingless. Genes & Development. 16: 1055-9. PMID 12000788 DOI: 10.1101/gad.991802  1
2002 Moreno E, Basler K, Morata G. Cells compete for decapentaplegic survival factor to prevent apoptosis in Drosophila wing development. Nature. 416: 755-9. PMID 11961558 DOI: 10.1038/416755A  1
2002 Kramps T, Peter O, Brunner E, Nellen D, Froesch B, Chatterjee S, Murone M, Züllig S, Basler K. Wnt/wingless signaling requires BCL9/legless-mediated recruitment of pygopus to the nuclear beta-catenin-TCF complex. Cell. 109: 47-60. PMID 11955446 DOI: 10.1016/S0092-8674(02)00679-7  1
2002 Gerlitz O, Nellen D, Ottiger M, Basler K. A screen for genes expressed in Drosophila imaginal discs. The International Journal of Developmental Biology. 46: 173-6. PMID 11902680 DOI: 10.1387/Ijdb.11902680  1
2002 Bellotto M, Bopp D, Senti KA, Burke R, Deak P, Maroy P, Dickson B, Basler K, Hafen E. Maternal-effect loci involved in Drosophila oogenesis and embryogenesis: P element-induced mutations on the third chromosome. The International Journal of Developmental Biology. 46: 149-57. PMID 11902676 DOI: 10.1387/Ijdb.11902676  1
2001 Hasson P, Müller B, Basler K, Paroush Z. Brinker requires two corepressors for maximal and versatile repression in Dpp signalling. The Embo Journal. 20: 5725-36. PMID 11598015 DOI: 10.1093/Emboj/20.20.5725  1
2001 Chamoun Z, Mann RK, Nellen D, von Kessler DP, Bellotto M, Beachy PA, Basler K. Skinny hedgehog, an acyltransferase required for palmitoylation and activity of the hedgehog signal. Science (New York, N.Y.). 293: 2080-4. PMID 11486055 DOI: 10.1126/science.1064437  1
2001 Méthot N, Basler K. An absolute requirement for Cubitus interruptus in Hedgehog signaling. Development (Cambridge, England). 128: 733-42. PMID 11171398 DOI: 10.5167/Uzh-972  1
2000 Sivasankaran R, Vigano MA, Müller B, Affolter M, Basler K. Direct transcriptional control of the Dpp target omb by the DNA binding protein Brinker. The Embo Journal. 19: 6162-72. PMID 11080162 DOI: 10.1093/emboj/19.22.6162  1
2000 Marty T, Müller B, Basler K, Affolter M. Schnurri mediates Dpp-dependent repression of brinker transcription. Nature Cell Biology. 2: 745-9. PMID 11025666 DOI: 10.1038/35036383  1
2000 Méthot N, Basler K. Suppressor of fused opposes hedgehog signal transduction by impeding nuclear accumulation of the activator form of Cubitus interruptus. Development (Cambridge, England). 127: 4001-10. PMID 10952898 DOI: 10.5167/Uzh-975  1
2000 Müller B, Basler K. The repressor and activator forms of Cubitus interruptus control Hedgehog target genes through common generic gli-binding sites. Development (Cambridge, England). 127: 2999-3007. PMID 10862738  1
2000 Basler K. EMBO Gold Medal 1999. Waiting periods, instructive signals and positional information. The Embo Journal. 19: 1168-75. PMID 10716916 DOI: 10.1093/Emboj/19.6.1169  1
2000 Sivasankaran R, Calleja M, Morata G, Basler K. The Wingless target gene Dfz3 encodes a new member of the Drosophila Frizzled family. Mechanisms of Development. 91: 427-31. PMID 10704878 DOI: 10.1016/S0925-4773(99)00313-5  1
2000 Dahmann C, Basler K. Opposing transcriptional outputs of Hedgehog signaling and engrailed control compartmental cell sorting at the Drosophila A/P boundary. Cell. 100: 411-22. PMID 10693758 DOI: 10.1016/S0092-8674(00)80677-7  1
2000 Jenni M, Basler K, Hafen E, Aguet M. A newly founded Swiss biotech company Chimia. 54: 236-238.  1
2000 Basler K. Waiting periods, instructive signals and positional information Embo Journal. 19: 1169-1175.  1
1999 Burke R, Nellen D, Bellotto M, Hafen E, Senti KA, Dickson BJ, Basler K. Dispatched, a novel sterol-sensing domain protein dedicated to the release of cholesterol-modified hedgehog from signaling cells. Cell. 99: 803-15. PMID 10619433 DOI: 10.1016/S0092-8674(00)81677-3  1
1999 von Mering C, Basler K. Distinct and regulated activities of human Gli proteins in Drosophila. Current Biology : Cb. 9: 1319-22. PMID 10574767 DOI: 10.1016/S0960-9822(00)80054-8  1
1999 Morata G, Basler K. Cells in search of a signal. Nature Cell Biology. 1: E60-1. PMID 10559910 DOI: 10.1038/11113  1
1999 Dahmann C, Basler K. Compartment boundaries: at the edge of development. Trends in Genetics : Tig. 15: 320-6. PMID 10431194 DOI: 10.1016/S0168-9525(99)01774-6  1
1999 Méthot N, Basler K. Hedgehog controls limb development by regulating the activities of distinct transcriptional activator and repressor forms of Cubitus interruptus. Cell. 96: 819-31. PMID 10102270 DOI: 10.1016/S0092-8674(00)80592-9  1
1999 Brunner E, Brunner D, Fu W, Hafen E, Basler K. The dominant mutation Glazed is a gain-of-function allele of wingless that, similar to loss of APC, interferes with normal eye development. Developmental Biology. 206: 178-88. PMID 9986731 DOI: 10.1006/Dbio.1998.9136  1
1998 Schweizer L, Basler K. Drosophila ci(D) encodes a hybrid Pangolin/cubitus interruptus protein that diverts the wingless into the Hedgehog signaling pathway Mechanisms of Development. 78: 141-151. PMID 9858713 DOI: 10.1016/S0925-4773(98)00163-4  1
1997 Rodriguez I, Basler K. Control of compartmental affinity boundaries by Hedgehog Nature. 389: 614-618. PMID 9335503 DOI: 10.1038/39343  1
1997 Brunner E, Peter O, Schweizer L, Basler K. pangolin encodes a Lef-1 homologue that acts downstream of Armadillo to transduce the Wingless signal in Drosophila Nature. 385: 829-833. PMID 9039917 DOI: 10.1038/385829a0  1
1997 Burke R, Basler K. Hedgehog signaling in Drosophila eye and limb development - Conserved machinery, divergent roles? Current Opinion in Neurobiology. 7: 55-61. PMID 9039793 DOI: 10.1016/S0959-4388(97)80120-1  1
1996 Zecca M, Basler K, Struhl G. Direct and long-range action of a wingless morphogen gradient. Cell. 87: 833-44. PMID 8945511 DOI: 10.1016/S0092-8674(00)81991-1  1
1996 Burke R, Basler K. Hedgehog-dependent patterning in the Drosophila eye can occur in the absence of Dpp signaling Developmental Biology. 179: 360-368. PMID 8903352 DOI: 10.1006/dbio.1996.0267  1
1996 Burke R, Basler K. Dpp receptors are autonomously required for cell proliferation in the entire developing Drosophila wing Development. 122: 2261-2269. PMID 8681806  1
1996 Domínguez M, Brunner M, Hafen E, Basler K. Sending and receiving the hedgehog signal: control by the Drosophila Gli protein Cubitus interruptus. Science (New York, N.Y.). 272: 1621-5. PMID 8658135 DOI: 10.1126/Science.272.5268.1621  1
1996 Nellen D, Burke R, Struhl G, Basler K. Direct and long-range action of a DPP morphogen gradient. Cell. 85: 357-68. PMID 8616891 DOI: 10.1016/S0092-8674(00)81114-9  1
1995 Grieder NC, Nellen D, Burke R, Basler K, Affolter M. schnurri is required for drosophila Dpp signaling and encodes a zinc finger protein similar to the mammalian transcription factor PRDII-BF1 Cell. 81: 791-800. PMID 7774018 DOI: 10.1016/0092-8674(95)90540-5  1
1995 Ruberte E, Marty T, Nellen D, Affolter M, Basler K. An absolute requirement for both the type II and type I receptors, punt and thick veins, for dpp signaling in vivo. Cell. 80: 889-97. PMID 7697719 DOI: 10.1016/0092-8674(95)90292-9  1
1995 Zecca M, Basler K, Struhl G. Sequential organizing activities of engrailed, hedgehog and decapentaplegic in the Drosophila wing. Development (Cambridge, England). 121: 2265-78. PMID 7671794  1
1994 Basler K, Struhl G. Compartment boundaries and the control of Drosophila limb pattern by hedgehog protein. Nature. 368: 208-14. PMID 8145818 DOI: 10.1038/368208a0  1
1994 Nellen D, Affolter M, Basler K. Receptor serine/threonine kinases implicated in the control of Drosophila body pattern by decapentaplegic Cell. 78: 225-237. PMID 8044837 DOI: 10.1016/0092-8674(94)90293-3  1
1994 Affolter M, Nellen D, Nussbaumer U, Basler K. Multiple requirements for the receptor serine/threonine kinase thick veins reveal novel functions of TGFβ homologs during Drosophila embryogenesis Development. 120: 3105-3117. PMID 7720555 DOI: 10.5167/Uzh-1050  1
1993 Struhl G, Basler K. Organizing activity of wingless protein in Drosophila. Cell. 72: 527-40. PMID 8440019 DOI: 10.1016/0092-8674(93)90072-X  1
1993 Kussick SJ, Basler K, Cooper JA. Ras1-dependent signaling by ectopically-expressed Drosophila src gene product in the embryo and developing eye Oncogene. 8: 2791-2803. PMID 8378088  1
1993 Basler K, Edlund T, Jessell TM, Yamada T. Control of cell pattern in the neural tube: regulation of cell differentiation by dorsalin-1, a novel TGF beta family member. Cell. 73: 687-702. PMID 7916656 DOI: 10.1016/0092-8674(93)90249-P  1
1992 Dambly-Chaudière C, Jamet E, Burri M, Bopp D, Basler K, Hafen E, Dumont N, Spielmann P, Ghysen A, Noll M. The paired box gene pox neuro: a determinant of poly-innervated sense organs in Drosophila. Cell. 69: 159-72. PMID 1348214 DOI: 10.1016/0092-8674(92)90127-X  1
1991 Basler K, Christen B, Hafen E. Ligand-independent activation of the sevenless receptor tyrosine kinase changes the fate of cells in the developing Drosophila eye. Cell. 64: 1069-81. PMID 2004416 DOI: 10.1016/0092-8674(91)90262-W  1
1991 Basler K, Hafen E. Specification of cell fate in the developing eye of Drosophila. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 13: 621-31. PMID 1789779 DOI: 10.1002/Bies.950131202  1
1991 Hafen E, Basler K. Specification of cell fate in the developing eye of Drosophila. Development (Cambridge, England). Supplement. 1: 123-30. PMID 1742497  1
1990 Hafen E, Basler K. Role of receptor tyrosine kinases during Drosophila development. Ciba Foundation Symposium. 150: 191-204; discussion . PMID 2164907  1
1990 Hafen E, Basler K. Mechanisms of positional signalling in the developing eye of Drosophila studied by ectopic expression of sevenless and rough. Journal of Cell Science. Supplement. 13: 157-68. PMID 1982113 DOI: 10.1242/Jcs.1990.Supplement_13.15  1
1990 Basler K, Yen D, Tomlinson A, Hafen E. Reprogramming cell fate in the developing Drosophila retina: transformation of R7 cells by ectopic expression of rough. Genes & Development. 4: 728-39. PMID 1974229 DOI: 10.1101/Gad.4.5.728  1
1990 Basler K, Hafen E. Receptor tyrosine kinases mediate cell-cell interactions during Drosophila development. Progress in Growth Factor Research. 2: 15-27. PMID 1966557 DOI: 10.1016/0955-2235(90)90007-7  1
1989 Basler K, Siegrist P, Hafen E. The spatial and temporal expression pattern of sevenless is exclusively controlled by gene-internal elements. The Embo Journal. 8: 2381-6. PMID 2792089 DOI: 10.1002/J.1460-2075.1989.Tb08367.X  1
1989 Basler K, Hafen E. Dynamics of Drosophila eye development and temporal requirements of sevenless expression. Development (Cambridge, England). 107: 723-31. PMID 2632232  1
1989 Basler K, Hafen E. Ubiquitous expression of sevenless: position-dependent specification of cell fate. Science (New York, N.Y.). 243: 931-4. PMID 2493159 DOI: 10.1126/Science.2493159  1
1988 Basler K, Hafen E. Sevenless and Drosophila eye development: a tyrosine kinase controls cell fate. Trends in Genetics : Tig. 4: 74-9. PMID 3076295 DOI: 10.1016/0168-9525(88)90044-3  1
1988 Basler K, Hafen E. Control of photoreceptor cell fate by the sevenless protein requires a functional tyrosine kinase domain. Cell. 54: 299-311. PMID 2840202  1
1987 Hafen E, Basler K, Edstroem JE, Rubin GM. Sevenless, a cell-specific homeotic gene of Drosophila, encodes a putative transmembrane receptor with a tyrosine kinase domain. Science (New York, N.Y.). 236: 55-63. PMID 2882603 DOI: 10.1126/Science.2882603  1
1986 Basler K, Oesch B, Scott M, Westaway D, Wälchli M, Groth DF, McKinley MP, Prusiner SB, Weissmann C. Scrapie and cellular PrP isoforms are encoded by the same chromosomal gene. Cell. 46: 417-28. PMID 2873895 DOI: 10.1016/0092-8674(86)90662-8  1
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