Year |
Citation |
Score |
2022 |
Arneaud SLB, McClendon J, Tatge L, Watterson A, Zuurbier KR, Madhu B, Gumienny TL, Douglas PM. Reduced bone morphogenic protein signaling along the gut-neuron axis by heat shock factor promotes longevity. Aging Cell. e13693. PMID 35977034 DOI: 10.1111/acel.13693 |
0.32 |
|
2020 |
Ramadurgum P, Woodard DR, Daniel S, Peng H, Mallipeddi PL, Niederstrasser H, Mihelakis M, Chau VQ, Douglas PM, Posner BA, Hulleman JD. Simultaneous Control of Endogenous and User-Defined Genetic Pathways Using Unique ecDHFR Pharmacological Chaperones. Cell Chemical Biology. PMID 32330442 DOI: 10.1016/J.Chembiol.2020.03.006 |
0.329 |
|
2019 |
Egge N, Arneaud SLB, Wales P, Mihelakis M, McClendon J, Fonseca RS, Savelle C, Gonzalez I, Ghorashi A, Yadavalli S, Lehman WJ, Mirzaei H, Douglas PM. Age-Onset Phosphorylation of a Minor Actin Variant Promotes Intestinal Barrier Dysfunction. Developmental Cell. 51: 587-601.e7. PMID 31794717 DOI: 10.1016/J.Devcel.2019.11.001 |
0.348 |
|
2017 |
Das R, Melo JA, Thondamal M, Morton EA, Cornwell AB, Crick B, Kim JH, Swartz EW, Lamitina T, Douglas PM, Samuelson AV. The homeodomain-interacting protein kinase HPK-1 preserves protein homeostasis and longevity through master regulatory control of the HSF-1 chaperone network and TORC1-restricted autophagy in Caenorhabditis elegans. Plos Genetics. 13: e1007038. PMID 29036198 DOI: 10.1371/Journal.Pgen.1007038 |
0.541 |
|
2016 |
Arneaud SL, Douglas PM. The Stress Response Paradox: Fighting Degeneration at the Cost of Cancer. The Febs Journal. PMID 27225066 DOI: 10.1111/Febs.13764 |
0.335 |
|
2015 |
Douglas PM, Baird NA, Simic MS, Uhlein S, McCormick MA, Wolff SC, Kennedy BK, Dillin A. Heterotypic Signals from Neural HSF-1 Separate Thermotolerance from Longevity. Cell Reports. 12: 1196-204. PMID 26257177 DOI: 10.1016/J.Celrep.2015.07.026 |
0.701 |
|
2014 |
Baird NA, Douglas PM, Simic MS, Grant AR, Moresco JJ, Wolff SC, Yates JR, Manning G, Dillin A. HSF-1-mediated cytoskeletal integrity determines thermotolerance and life span. Science (New York, N.Y.). 346: 360-3. PMID 25324391 DOI: 10.1126/Science.1253168 |
0.711 |
|
2014 |
Douglas PM, Dillin A. The disposable soma theory of aging in reverse. Cell Research. 24: 7-8. PMID 24189044 DOI: 10.1038/Cr.2013.148 |
0.516 |
|
2012 |
Vilchez D, Morantte I, Liu Z, Douglas PM, Merkwirth C, Rodrigues AP, Manning G, Dillin A. RPN-6 determines C. elegans longevity under proteotoxic stress conditions. Nature. 489: 263-8. PMID 22922647 DOI: 10.1038/Nature11315 |
0.632 |
|
2010 |
Douglas PM, Dillin A. Protein homeostasis and aging in neurodegeneration. The Journal of Cell Biology. 190: 719-29. PMID 20819932 DOI: 10.1083/Jcb.201005144 |
0.649 |
|
2010 |
Douglas PM, Cyr DM. Interplay between protein homeostasis networks in protein aggregation and proteotoxicity. Biopolymers. 93: 229-36. PMID 19768782 DOI: 10.1002/Bip.21304 |
0.648 |
|
2009 |
Douglas PM, Summers DW, Ren HY, Cyr DM. Reciprocal efficiency of RNQ1 and polyglutamine detoxification in the cytosol and nucleus. Molecular Biology of the Cell. 20: 4162-73. PMID 19656852 DOI: 10.1091/Mbc.E09-02-0170 |
0.711 |
|
2009 |
Summers DW, Douglas PM, Cyr DM. Prion propagation by Hsp40 molecular chaperones. Prion. 3: 59-64. PMID 19535913 DOI: 10.4161/Pri.3.2.9062 |
0.722 |
|
2009 |
Douglas PM, Summers DW, Cyr DM. Molecular chaperones antagonize proteotoxicity by differentially modulating protein aggregation pathways. Prion. 3: 51-8. PMID 19421006 DOI: 10.4161/Pri.3.2.8587 |
0.717 |
|
2009 |
Summers DW, Douglas PM, Ramos CH, Cyr DM. Polypeptide transfer from Hsp40 to Hsp70 molecular chaperones. Trends in Biochemical Sciences. 34: 230-3. PMID 19359181 DOI: 10.1016/J.Tibs.2008.12.009 |
0.708 |
|
2009 |
Summers DW, Douglas PM, Ren HY, Cyr DM. The type I Hsp40 Ydj1 utilizes a farnesyl moiety and zinc finger-like region to suppress prion toxicity. The Journal of Biological Chemistry. 284: 3628-39. PMID 19056735 DOI: 10.1074/Jbc.M807369200 |
0.703 |
|
2008 |
Douglas PM, Treusch S, Ren HY, Halfmann R, Duennwald ML, Lindquist S, Cyr DM. Chaperone-dependent amyloid assembly protects cells from prion toxicity. Proceedings of the National Academy of Sciences of the United States of America. 105: 7206-11. PMID 18480252 DOI: 10.1073/Pnas.0802593105 |
0.666 |
|
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