Nicholas E. Navin, Ph.D. - Publications

Affiliations: 
2010 Molecular Genetics and Microbiology Stony Brook University, Stony Brook, NY, United States 
Area:
Molecular Biology, Genetics, Oncology

106 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Dou J, Tan Y, Kock KH, Wang J, Cheng X, Tan LM, Han KY, Hon CC, Park WY, Shin JW, Jin H, Wang Y, Chen H, Ding L, Prabhakar S, ... Navin N, et al. Single-nucleotide variant calling in single-cell sequencing data with Monopogen. Nature Biotechnology. PMID 37592035 DOI: 10.1038/s41587-023-01873-x  0.315
2023 Wang K, Kumar T, Wang J, Minussi DC, Sei E, Li J, Tran TM, Thennavan A, Hu M, Casasent AK, Xiao Z, Bai S, Yang L, King LM, Shah V, ... ... Navin NE, et al. Archival single-cell genomics reveals persistent subclones during DCIS progression. Cell. PMID 37586362 DOI: 10.1016/j.cell.2023.07.024  0.444
2023 Kumar T, Nee K, Wei R, He S, Nguyen QH, Bai S, Blake K, Pein M, Gong Y, Sei E, Hu M, Casasent AK, Thennavan A, Li J, Tran T, ... ... Navin N, et al. A spatially resolved single-cell genomic atlas of the adult human breast. Nature. PMID 37380767 DOI: 10.1038/s41586-023-06252-9  0.315
2023 Truong DD, Lamhamedi-Cherradi SE, Porter RW, Krishnan S, Swaminathan J, Gibson A, Lazar AJ, Livingston JA, Gopalakrishnan V, Gordon N, Daw NC, Navin NE, Gorlick R, Ludwig JA. Dissociation protocols used for sarcoma tissues bias the transcriptome observed in single-cell and single-nucleus RNA sequencing. Bmc Cancer. 23: 488. PMID 37254069 DOI: 10.1186/s12885-023-10977-1  0.378
2023 Kumar T, Nee K, Wei R, He S, Nguyen QH, Bai S, Blake K, Gong Y, Pein M, Sei E, Hu M, Casasent A, Thennavan A, Li J, Tran T, ... ... Navin N, et al. A spatially resolved single cell genomic atlas of the adult human breast. Biorxiv : the Preprint Server For Biology. PMID 37163043 DOI: 10.1101/2023.04.22.537946  0.313
2023 Lu L, Wang JR, Henderson YC, Bai S, Yang J, Hu M, Shiau CK, Pan TY, Yan Y, Tran TM, Li J, Kieser R, Zhao X, Wang J, Nurieva R, ... ... Navin N, et al. Anaplastic transformation in thyroid cancer revealed by single cell transcriptomics. The Journal of Clinical Investigation. PMID 37053016 DOI: 10.1172/JCI169653  0.326
2022 Leighton J, Hu M, Sei E, Meric-Bernstam F, Navin NE. Reconstructing mutational lineages in breast cancer by multi-patient-targeted single-cell DNA sequencing. Cell Genomics. 3: 100215. PMID 36777188 DOI: 10.1016/j.xgen.2022.100215  0.426
2022 Wu HJ, Temko D, Maliga Z, Moreira AL, Sei E, Minussi DC, Dean J, Lee C, Xu Q, Hochart G, Jacobson CA, Yapp C, Schapiro D, Sorger PK, Seeley EH, ... Navin N, et al. Spatial intra-tumor heterogeneity is associated with survival of lung adenocarcinoma patients. Cell Genomics. 2. PMID 36419822 DOI: 10.1016/j.xgen.2022.100165  0.331
2022 Kaufmann TL, Petkovic M, Watkins TBK, Colliver EC, Laskina S, Thapa N, Minussi DC, Navin N, Swanton C, Van Loo P, Haase K, Tarabichi M, Schwarz RF. MEDICC2: whole-genome doubling aware copy-number phylogenies for cancer evolution. Genome Biology. 23: 241. PMID 36376909 DOI: 10.1186/s13059-022-02794-9  0.39
2022 Schalck A, Sakellariou-Thompson D, Forget MA, Sei E, Hughes TG, Reuben A, Bai S, Hu M, Kumar T, Hurd MW, Katz MHG, Tzeng CD, Pant S, Javle M, Fogelman DR, ... ... Navin NE, et al. Single cell sequencing reveals trajectory of tumor-infiltrating lymphocyte states in pancreatic cancer. Cancer Discovery. PMID 35849783 DOI: 10.1158/2159-8290.CD-21-1248  0.306
2022 Lips EH, Kumar T, Megalios A, Visser LL, Sheinman M, Fortunato A, Shah V, Hoogstraat M, Sei E, Mallo D, Roman-Escorza M, Ahmed AA, Xu M, van den Belt-Dusebout AW, Brugman W, ... ... Navin NE, et al. Genomic analysis defines clonal relationships of ductal carcinoma in situ and recurrent invasive breast cancer. Nature Genetics. 54: 850-860. PMID 35681052 DOI: 10.1038/s41588-022-01082-3  0.41
2021 Minussi DC, Nicholson MD, Ye H, Davis A, Wang K, Baker T, Tarabichi M, Sei E, Du H, Rabbani M, Peng C, Hu M, Bai S, Lin YW, Schalck A, ... ... Navin NE, et al. Breast tumours maintain a reservoir of subclonal diversity during expansion. Nature. PMID 33762732 DOI: 10.1038/s41586-021-03357-x  0.395
2021 Wang F, Wang Q, Mohanty V, Liang S, Dou J, Han J, Minussi DC, Gao R, Ding L, Navin N, Chen K. MEDALT: single-cell copy number lineage tracing enabling gene discovery. Genome Biology. 22: 70. PMID 33622385 DOI: 10.1186/s13059-021-02291-5  0.366
2021 Gao R, Bai S, Henderson YC, Lin Y, Schalck A, Yan Y, Kumar T, Hu M, Sei E, Davis A, Wang F, Shaitelman SF, Wang JR, Chen K, Moulder S, ... ... Navin NE, et al. Delineating copy number and clonal substructure in human tumors from single-cell transcriptomes. Nature Biotechnology. PMID 33462507 DOI: 10.1038/s41587-020-00795-2  0.505
2020 Naffar-Abu Amara S, Kuiken HJ, Selfors LM, Butler T, Leung ML, Leung CT, Kuhn EP, Kolarova T, Hage C, Ganesh K, Panayiotou R, Foster R, Rueda BR, Aktipis A, Spellman P, ... ... Navin N, et al. Transient commensal clonal interactions can drive tumor metastasis. Nature Communications. 11: 5799. PMID 33199705 DOI: 10.1038/s41467-020-19584-1  0.316
2020 Morita K, Wang F, Jahn K, Hu T, Tanaka T, Sasaki Y, Kuipers J, Loghavi S, Wang SA, Yan Y, Furudate K, Matthews J, Little L, Gumbs C, Zhang J, ... ... Navin N, et al. Clonal evolution of acute myeloid leukemia revealed by high-throughput single-cell genomics. Nature Communications. 11: 5327. PMID 33087716 DOI: 10.1038/s41467-020-19119-8  0.382
2020 Mallory XF, Edrisi M, Navin N, Nakhleh L. Methods for copy number aberration detection from single-cell DNA-sequencing data. Genome Biology. 21: 208. PMID 32807205 DOI: 10.1186/S13059-020-02119-8  0.413
2020 Mallory XF, Edrisi M, Navin N, Nakhleh L. Assessing the performance of methods for copy number aberration detection from single-cell DNA sequencing data. Plos Computational Biology. 16: e1008012. PMID 32658894 DOI: 10.1371/Journal.Pcbi.1008012  0.462
2020 Ramesh N, Sei E, Tsai PC, Bai S, Zhao Y, Troncoso P, Corn PG, Logothetis C, Zurita AJ, Navin NE. Decoding the evolutionary response to prostate cancer therapy by plasma genome sequencing. Genome Biology. 21: 162. PMID 32631448 DOI: 10.1186/S13059-020-02045-9  0.4
2020 Manzo T, Prentice BM, Anderson KG, Raman A, Schalck A, Codreanu GS, Nava Lauson CB, Tiberti S, Raimondi A, Jones MA, Reyzer M, Bates BM, Spraggins JM, Patterson NH, McLean JA, ... ... Navin NE, et al. Accumulation of long-chain fatty acids in the tumor microenvironment drives dysfunction in intrapancreatic CD8+ T cells. The Journal of Experimental Medicine. 217. PMID 32491160 DOI: 10.1084/Jem.20191920  0.337
2020 Malihi PD, Graf RP, Rodriguez A, Ramesh N, Lee J, Sutton R, Jiles R, Ruiz Velasco C, Sei E, Kolatkar A, Logothetis C, Navin NE, Corn P, Aparicio AM, Dittamore R, et al. Single-cell circulating tumor cell analysis reveals genomic instability as a distinctive feature of aggressive prostate cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 32341031 DOI: 10.1158/1078-0432.Ccr-19-4100  0.492
2020 Mitra A, Andrews MC, Roh W, De Macedo MP, Hudgens CW, Carapeto F, Singh S, Reuben A, Wang F, Mao X, Song X, Wani K, Tippen S, Ng KS, Schalck A, ... ... Navin N, et al. Spatially resolved analyses link genomic and immune diversity and reveal unfavorable neutrophil activation in melanoma. Nature Communications. 11: 1839. PMID 32296058 DOI: 10.1038/S41467-020-15538-9  0.458
2020 Lim B, Lin Y, Navin N. Advancing Cancer Research and Medicine with Single-Cell Genomics. Cancer Cell. 37: 456-470. PMID 32289270 DOI: 10.1016/J.Ccell.2020.03.008  0.457
2020 Oikawa M, Enomoto Y, Hisamatsu K, Hamada T, Otsubo R, Yano H, Nagayasu T, Mishima H, Yoshiura K, Navin N. Abstract P5-01-17: Unbiased copy number analysis of circulating tumor DNA among HER2-positive breast cancer patients Cancer Research. 80. DOI: 10.1158/1538-7445.Sabcs19-P5-01-17  0.513
2020 Mastoraki S, Navarro-Yepes J, Tran T, Sahin A, Hunt K, Navin N, Keyomarsi K. Abstract P4-06-03: Assessment of intratumoral heterogeneity in early stage estrogen receptor (ER) positive breast cancer Cancer Research. 80. DOI: 10.1158/1538-7445.Sabcs19-P4-06-03  0.517
2020 Kumar T, Nguyen Q, Nee K, Bai S, Hu M, Sei E, Wood A, Wiley J, Chen H, Contreras A, Teshome M, Chen K, Lim B, Lawson D, Navin N, et al. Abstract 5702: A spatially resolved single cell atlas of the human breast Tumor Biology. DOI: 10.1158/1538-7445.Am2020-5702  0.35
2019 Davis A, Gao R, Navin NE. SCOPIT: sample size calculations for single-cell sequencing experiments. Bmc Bioinformatics. 20: 566. PMID 31718533 DOI: 10.1186/S12859-019-3167-9  0.43
2019 Wang F, Liang S, Kumar T, Navin N, Chen K. SCMarker: Ab initio marker selection for single cell transcriptome profiling. Plos Computational Biology. 15: e1007445. PMID 31658262 DOI: 10.1371/Journal.Pcbi.1007445  0.369
2019 Zafar H, Navin N, Chen K, Nakhleh L. SiCloneFit: Bayesian inference of population structure, genotype, and phylogeny of tumor clones from single-cell genome sequencing data. Genome Research. PMID 31628257 DOI: 10.1101/Gr.243121.118  0.48
2019 Corn PG, Heath EI, Zurita A, Ramesh N, Xiao L, Sei E, Li-Ning-Tapia E, Tu SM, Subudhi SK, Wang J, Wang X, Efstathiou E, Thompson TC, Troncoso P, Navin N, et al. Cabazitaxel plus carboplatin for the treatment of men with metastatic castration-resistant prostate cancers: a randomised, open-label, phase 1-2 trial. The Lancet. Oncology. PMID 31515154 DOI: 10.1016/S1470-2045(19)30408-5  0.301
2019 Zafar H, Tzen A, Navin N, Chen K, Nakhleh L. Comments on the model parameters in "SiFit: inferring tumor trees from single-cell sequencing data under finite-sites models". Genome Biology. 20: 95. PMID 31096998 DOI: 10.1186/S13059-019-1692-5  0.404
2019 Aparicio A, Zhang M, Ramesh N, Wang X, Corn PG, Zurita AJ, Davis JW, Pettaway CA, Adibi M, Mcguire SE, Tu S, Wang J, Subudhi SK, Elsheshtawi MA, Efstathiou E, ... ... Navin N, et al. Aggressive variant prostate cancer (AVPC) molecular signature in castration-sensitive, de novo metastatic prostate cancer (M1PCa). Journal of Clinical Oncology. 37: 5052-5052. DOI: 10.1200/Jco.2019.37.15_Suppl.5052  0.359
2019 Issa GC, Benton CB, Mohanty V, Shen Y, Alaniz Z, Wang F, Futreal PA, Wang W, Jorgensen JL, Navin N, Konopleva MY, Chen K, Andreeff M. Identification of Gene Expression Signatures in Leukemia Stem Cells and Minimal Residual Disease Following Treatment of Adverse Risk Acute Myeloid Leukemia Blood. 134: 2717-2717. DOI: 10.1182/Blood-2019-130540  0.385
2019 Navin N. Abstract PL1: Breast Tumor Evolution and Intratumor Heterogeneity - Insights from Single Cell Genomics Cancer Research. 79. DOI: 10.1158/1538-7445.Sabcs18-Pl1  0.539
2019 Seth T, Bai S, Hu M, Sei E, Wood A, Wiley J, Chen H, Contreras A, Teshome M, Lim B, Navin N. Abstract GS1-02: Towards a human breast cell atlas Cancer Research. 79. DOI: 10.1158/1538-7445.Sabcs18-Gs1-02  0.445
2019 Ramesh N, Sei E, Tsai PC, Logothetis C, Corn P, Aparicio A, Zurita AJ, Navin NE. Abstract 446: Plasma genome sequencing identifies prostate cancer patients that are sensitive to platinum-based therapy Cancer Research. DOI: 10.1158/1538-7445.Sabcs18-446  0.389
2019 Mitra A, Andrews MC, Roh W, Macedo MPd, Reuben A, Carapeto F, Wang F, Reddy SM, Wani K, Spencer C, Miller J, Schalck A, Little LD, Sakellariou-Thompson DA, Gumbs C, ... ... Navin N, et al. Abstract 3776: Spatially resolved immunogenomic analyses reveal diverse sub tumoral microenvironments in the context of melanoma immunotherapy Cancer Research. 79: 3776-3776. DOI: 10.1158/1538-7445.Sabcs18-3776  0.462
2019 Hughes T, Li X, Dai B, Deng J, Siangco C, Das K, Bai S, Hu M, Sei E, Seth T, Navin N, Kim M. Abstract 2738: Wnt11 regulates migration and invasion in pancreatic ductal adenocarcinoma Cancer Research. 79: 2738-2738. DOI: 10.1158/1538-7445.Sabcs18-2738  0.447
2019 Gao R, Navin N. Abstract 2477: CopyCat: estimating genomic copy number profiles from high-throughput single cell RNA seq data Cancer Research. 79: 2477-2477. DOI: 10.1158/1538-7445.Am2019-2477  0.511
2019 Hughes T, Li X, Dai B, Siangco C, Das K, Bai S, Min H, Kumar T, Sei E, Navin N, Kim MP. 727 – Wnt11 Promotes Pancreatic Cancer Cell Motility and Invasion Gastroenterology. 156. DOI: 10.1016/S0016-5085(19)40561-1  0.371
2019 Morita K, Wang F, Jahn K, Kuipers J, Yan Y, Matthews J, Little L, Gumbs C, Chen S, Zhang J, Song X, Thompson E, Patel K, Bueso-Ramos C, DiNardo C, ... ... Navin N, et al. Deconvolution of Clonal Heterogeneity in Acute Myeloid Leukemia using Single-Cell DNA Sequencing Clinical Lymphoma Myeloma and Leukemia. 19: S234. DOI: 10.1016/J.Clml.2019.07.121  0.369
2018 Zhang Y, Xiong S, Liu B, Pant V, Celii F, Chau G, Elizondo-Fraire AC, Yang P, You MJ, El-Naggar AK, Navin NE, Lozano G. Somatic Trp53 mutations differentially drive breast cancer and evolution of metastases. Nature Communications. 9: 3953. PMID 30262850 DOI: 10.1038/S41467-018-06146-9  0.466
2018 Schalck A, Bernatchez C, Navin N. Resident Breast T Cells: The Troops Are Already There Trends in Molecular Medicine. 24: 821-822. PMID 30077643 DOI: 10.1016/J.Molmed.2018.07.006  0.424
2018 Kim C, Gao R, Sei E, Brandt R, Hartman J, Hatschek T, Crosetto N, Foukakis T, Navin NE. Chemoresistance Evolution in Triple-Negative Breast Cancer Delineated by Single-Cell Sequencing. Cell. PMID 29681456 DOI: 10.1016/J.Cell.2018.03.041  0.497
2018 Benton CB, Al Rawi A, Wang F, Zhang J, Jorgensen JL, Mu H, Schober W, Alaniz Z, Gumbs C, Futreal A, Garcia-Manero G, Kantarjian HM, Navin N, Konopleva MY, Andreeff M. Distinct Gene Expression Patterns of Minimal Residual Disease (MRD) Cells in High-Risk AML Patients Identified By RNA-Sequencing Blood. 132: 2757-2757. DOI: 10.1182/Blood-2018-99-120260  0.369
2018 Oikawa M, Ramesh N, Sei E, Bai S, Hu M, John dGF, Rshmi M, O'Brien B, Navin N. Abstract 5599: Noninvasive genomic profiling of cerebral spinal fluid in breast cancer patient with leptomeningeal disease Cancer Research. 78: 5599-5599. DOI: 10.1158/1538-7445.Am2018-5599  0.486
2018 Ramesh N, Sei E, Gao R, Tsai PC, Logothetis C, Zurita AJ, Navin NE. Abstract 3665: Longitudinal monitoring of prostate cancer evolution by plasma genome sequencing Cancer Research. 78: 3665-3665. DOI: 10.1158/1538-7445.Am2018-3665  0.487
2018 Du H, Davis A, Gao R, Colic M, Sei E, Hu M, Barrera AG, Casasent A, Albarracin C, Arun B, Navin NE. Abstract 2192: Single-molecule single-cell DNA sequencing identifies ongoing copy number evolution in BRCA breast cancers Cancer Research. 78: 2192-2192. DOI: 10.1158/1538-7445.Am2018-2192  0.565
2018 Zafar H, Navin N, Nakhleh L, Chen K. Computational approaches for inferring tumor evolution from single-cell genomic data Current Opinion in Systems Biology. 7: 16-25. DOI: 10.1016/J.Coisb.2017.11.008  0.533
2017 Casasent AK, Schalck A, Gao R, Sei E, Long A, Pangburn W, Casasent T, Meric-Bernstam F, Edgerton ME, Navin NE. Multiclonal Invasion in Breast Tumors Identified by Topographic Single Cell Sequencing. Cell. PMID 29307488 DOI: 10.1016/J.Cell.2017.12.007  0.542
2017 Zafar H, Tzen A, Navin N, Chen K, Nakhleh L. SiFit: inferring tumor trees from single-cell sequencing data under finite-sites models. Genome Biology. 18: 178. PMID 28927434 DOI: 10.1186/S13059-017-1311-2  0.465
2017 Gao R, Kim C, Sei E, Foukakis T, Crosetto N, Chan LK, Srinivasan M, Zhang H, Meric-Bernstam F, Navin N. Nanogrid single-nucleus RNA sequencing reveals phenotypic diversity in breast cancer. Nature Communications. 8: 228. PMID 28794488 DOI: 10.1038/S41467-017-00244-W  0.507
2017 Gausachs M, Borras E, Chang K, González S, Azuara D, Delgado Amador A, Lopez-Doriga A, San Lucas FA, Sanjuan X, Paules MJ, Taggart M, Davies G, Ehli EA, Fowler J, Moreno V, ... ... Navin NE, et al. Mutational Heterogeneity in APC and KRAS Arises at the Crypt level and Leads to Polyclonality in Early Colorectal Tumorigenesis. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 28645942 DOI: 10.1158/1078-0432.Ccr-17-0821  0.341
2017 Leung ML, Davis A, Gao R, Casasent A, Wang Y, Sei E, Sanchez E, Maru D, Kopetz S, Navin NE. Single cell DNA sequencing reveals a late-dissemination model in metastatic colorectal cancer. Genome Research. PMID 28546418 DOI: 10.1101/Gr.209973.116  0.529
2017 Davis A, Gao R, Navin N. Tumor Evolution: Linear, Branching, Neutral or Punctuated? Biochimica Et Biophysica Acta. PMID 28110020 DOI: 10.1016/J.Bbcan.2017.01.003  0.486
2017 Aparicio A, Xiao L, Tapia ELN, Hoang A, Ramesh N, Wu W, Chancoco H, Heath EI, Efstathiou E, Thompson TC, Troncoso P, Broom BM, Zurita AJ, Navin N, Logothetis C, et al. The aggressive variant prostate carcinoma (AVPC) molecular signature (-MS) and platinum-sensitivity in castration resistant prostate cancer (CRPC). Journal of Clinical Oncology. 35: 5013-5013. DOI: 10.1200/Jco.2017.35.15_Suppl.5013  0.365
2017 Gao R, Kim C, Sei E, Yang J, Chan L, Srinivasan M, Zhang H, Meric-Bernstam F, Navin NE. Abstract 5399: Investigating phenotypic plasticity in breast cancer with high-throughput nanogrid single-nucleus RNA sequencing Cancer Research. 77: 5399-5399. DOI: 10.1158/1538-7445.Am2017-5399  0.529
2017 Kim C, Gao R, Sei E, Brandt R, Crosetto N, Foukakis T, Navin N. Abstract 418: Adaptive resistance to chemotherapy in triple-negative breast cancer revealed by single cell DNA and RNA sequencing Cancer Research. 77: 418-418. DOI: 10.1158/1538-7445.Am2017-418  0.48
2016 Casasent A, Edgerton M, Navin NE. Genome evolution in ductal carcinoma in situ: invasion of the clones. The Journal of Pathology. PMID 27861897 DOI: 10.1002/Path.4840  0.429
2016 Chen X, Love JC, Navin NE, Pachter L, Stubbington MJ, Svensson V, Sweedler JV, Teichmann SA. Single-cell analysis at the threshold. Nature Biotechnology. 34: 1111-1118. PMID 27824834 DOI: 10.1038/Nbt.3721  0.349
2016 Gao R, Davis A, McDonald TO, Sei E, Shi X, Wang Y, Tsai PC, Casasent A, Waters J, Zhang H, Meric-Bernstam F, Michor F, Navin NE. Punctuated copy number evolution and clonal stasis in triple-negative breast cancer. Nature Genetics. PMID 27526321 DOI: 10.1038/Ng.3641  0.569
2016 Mann KM, Newberg JY, Black MA, Jones DJ, Amaya-Manzanares F, Guzman-Rojas L, Kodama T, Ward JM, Rust AG, van der Weyden L, Yew CC, Waters JL, Leung ML, Rogers K, Rogers SM, ... ... Navin N, et al. Analyzing tumor heterogeneity and driver genes in single myeloid leukemia cells with SBCapSeq. Nature Biotechnology. PMID 27479497 DOI: 10.1038/Nbt.3637  0.533
2016 Navin NE, Chen K. Genotyping tumor clones from single-cell data. Nature Methods. 13: 555-556. PMID 27355792 DOI: 10.1038/Nmeth.3903  0.481
2016 Davis A, Navin NE. Computing tumor trees from single cells. Genome Biology. 17: 113. PMID 27230879 DOI: 10.1186/S13059-016-0987-Z  0.461
2016 Zafar H, Wang Y, Nakhleh L, Navin N, Chen K. Monovar: single-nucleotide variant detection in single cells. Nature Methods. PMID 27088313 DOI: 10.1038/Nmeth.3835  0.441
2016 Baslan T, Kendall J, Rodgers L, Cox H, Riggs M, Stepansky A, Troge J, Ravi K, Esposito D, Lakshmi B, Wigler M, Navin N, Hicks J. Corrigendum: Genome-wide copy number analysis of single cells. Nature Protocols. 11: 616. PMID 26914320 DOI: 10.1038/Nprot0316.616B  0.302
2016 Leung ML, Wang Y, Kim C, Gao R, Jiang J, Sei E, Navin NE. Highly multiplexed targeted DNA sequencing from single nuclei. Nature Protocols. 11: 214-235. PMID 26741407 DOI: 10.1038/Nprot.2016.005  0.432
2016 Clarke C, Korphaisarn K, Jiang Z, Crosby S, Davis DW, Wu W, Raghav KPS, Overman MJ, Morris VK, Kee BK, Eng C, Fogelman DR, Navin N, Kopetz S. Antibody-independent isolation and characterization of circulating tumor cells using dielectrophoresis: Fluid flow fractionation in metastatic colorectal cancer. Journal of Clinical Oncology. 34. DOI: 10.1200/Jco.2016.34.15_Suppl.E23023  0.434
2016 Casasent AK, Long AN, Schalck A, Sei E, Gao R, Davis A, Wang Y, Edgerton ME, Navin NE. Abstract 2375: Multiclonal invasion in breast cancer identified by single cell DNA sequencing Cancer Research. 76: 2375-2375. DOI: 10.1158/1538-7445.Am2016-2375  0.528
2016 Davis AJ, Gao R, Sei E, Tsai P, Casasent A, Zhang A, Shi X, Wang Y, Waters J, Meric-Bernstam F, Edgerton M, Navin N. Abstract 2371: Multi-cell phylogenetic inference of copy number evolution in breast cancer Cancer Research. 76: 2371-2371. DOI: 10.1158/1538-7445.Am2016-2371  0.577
2016 Leung ML, Casasent A, Wang Y, Sei E, Navin N. Abstract 157: Single-cell DNA sequencing identifies a late dissemination model in metastatic colorectal cancer Cancer Research. 76: 157-157. DOI: 10.1158/1538-7445.Am2016-157  0.564
2015 Navin NE. The first five years of single-cell cancer genomics and beyond. Genome Research. 25: 1499-507. PMID 26430160 DOI: 10.1101/Gr.191098.115  0.495
2015 Alizadeh AA, Aranda V, Bardelli A, Blanpain C, Bock C, Borowski C, Caldas C, Califano A, Doherty M, Elsner M, Esteller M, Fitzgerald R, Korbel JO, Lichter P, Mason CE, ... Navin N, et al. Toward understanding and exploiting tumor heterogeneity. Nature Medicine. 21: 846-53. PMID 26248267 DOI: 10.1038/Nm.3915  0.388
2015 Navin NE. Delineating cancer evolution with single-cell sequencing. Science Translational Medicine. 7: 296fs29. PMID 26180099 DOI: 10.1126/scitranslmed.aac8319  0.391
2015 Wang Y, Navin NE. Advances and applications of single-cell sequencing technologies. Molecular Cell. 58: 598-609. PMID 26000845 DOI: 10.1016/J.Molcel.2015.05.005  0.388
2015 Leung ML, Wang Y, Waters J, Navin NE. SNES: single nucleus exome sequencing. Genome Biology. 16: 55. PMID 25853327 DOI: 10.1186/S13059-015-0616-2  0.42
2015 Malhotra A, Wang Y, Waters J, Chen K, Meric-Bernstam F, Hall IM, Navin NE. Ploidy-Seq: inferring mutational chronology by sequencing polyploid tumor subpopulations. Genome Medicine. 7: 6. PMID 25729435 DOI: 10.1186/S13073-015-0127-5  0.52
2015 Navin NE. Abstract IA22: Investigating breast cancer evolution and diversity with single-cell sequencing Clinical Cancer Research. 21. DOI: 10.1158/1557-3265.Pms14-Ia22  0.582
2015 Gao R, Davis A, Sei E, Shi X, Unruh A, Waters J, Zhang A(, Meric-Bernstam F, Navin N. Abstract LB-170: Single cell sequencing identifies clonal stasis and punctuated copy number evolution in triple-negative breast cancer patients Cancer Research. 75. DOI: 10.1158/1538-7445.Am2015-Lb-170  0.489
2015 Mann KM, Newberg J, Navin N, Adams DJ, Jenkins N, Copeland N, Mann MB. Abstract 2893: Sleeping Beauty uncovers cooperating driver genes in a preclinical mouse model of myeloid leukemia Cancer Research. 75: 2893-2893. DOI: 10.1158/1538-7445.Am2015-2893  0.467
2014 Navin NE. Cancer genomics: one cell at a time. Genome Biology. 15: 452. PMID 25222669 DOI: 10.1186/S13059-014-0452-9  0.472
2014 Wang Y, Waters J, Leung ML, Unruh A, Roh W, Shi X, Chen K, Scheet P, Vattathil S, Liang H, Multani A, Zhang H, Zhao R, Michor F, Meric-Bernstam F, ... Navin NE, et al. Clonal evolution in breast cancer revealed by single nucleus genome sequencing. Nature. 512: 155-60. PMID 25079324 DOI: 10.1038/Nature13600  0.489
2014 Navin NE. Tumor evolution in response to chemotherapy: phenotype versus genotype. Cell Reports. 6: 417-9. PMID 24529750 DOI: 10.1016/J.Celrep.2014.01.035  0.417
2014 Wang Y, Navin N, Waters J, Leung M, Unruh A, Shi X, Roh W, Chen K, Scheet P, Vattathil S, Liang H, Multani A, Zhang H, Meric-Bernstam F, Michor F, et al. Abstract LB-310: Single cell genome sequencing reveals clonal stability and diversity in breast cancer Cancer Research. 74. DOI: 10.1158/1538-7445.Am2014-Lb-310  0.59
2013 Chen K, Navin NE, Wang Y, Schmidt HK, Wallis JW, Niu B, Fan X, Zhao H, McLellan MD, Hoadley KA, Mardis ER, Ley TJ, Perou CM, Wilson RK, Ding L. BreakTrans: uncovering the genomic architecture of gene fusions. Genome Biology. 14: R87. PMID 23972288 DOI: 10.1186/Gb-2013-14-8-R87  0.456
2013 Larsson CA, Kojima K, Wang Y, Navin N, Gallardo M, Primo D, Rojas JL, Martinez J, Manshouri T, Lee HJ, Bradner JE, Ballesteros J, Post SM, Lozano G(, Quintás-Cardama A. BET Bromodomain Inhibition Reduces Leukemic Burden and Prolongs Survival In The Eμ-TCL1 Transgenic Mouse Model Of Chronic Lymphocytic Leukemia (CLL) Independent Of TP53 Mutation Status Blood. 122: 876-876. DOI: 10.1182/Blood.V122.21.876.876  0.313
2012 Baslan T, Kendall J, Rodgers L, Cox H, Riggs M, Stepansky A, Troge J, Ravi K, Esposito D, Lakshmi B, Wigler M, Navin N, Hicks J. Genome-wide copy number analysis of single cells. Nature Protocols. 7: 1024-41. PMID 22555242 DOI: 10.1038/Nprot.2012.039  0.448
2012 Navin NE, Wang Y, Waters J, Chen K, Hall I, Malhotra A, Quinlan A. Abstract 5054: Inferring mutational chronology in breast cancer by deep-sequencing tumor subpopulations Cancer Research. 72: 5054-5054. DOI: 10.1158/1538-7445.Am2012-5054  0.523
2012 Navin N. Abstract ES5-3: Investigating Breast Cancer with Single-Cell Sequencing Cancer Research. 72. DOI: 10.1158/0008-5472.Sabcs12-Es5-3  0.591
2011 Russnes HG, Navin N, Hicks J, Borresen-Dale AL. Insight into the heterogeneity of breast cancer through next-generation sequencing Journal of Clinical Investigation. 121: 3810-3818. PMID 21965338 DOI: 10.1172/Jci57088  0.547
2011 Chen M, Pratt CP, Zeeman ME, Schultz N, Taylor BS, O'Neill A, Castillo-Martin M, Nowak DG, Naguib A, Grace DM, Murn J, Navin N, Atwal GS, Sander C, Gerald WL, et al. Identification of PHLPP1 as a tumor suppressor reveals the role of feedback activation in PTEN-mutant prostate cancer progression. Cancer Cell. 20: 173-86. PMID 21840483 DOI: 10.1016/J.Ccr.2011.07.013  0.364
2011 Navin NE, Hicks J. Future medical applications of single-cell sequencing in cancer Genome Medicine. 3: 31-31. PMID 21631906 DOI: 10.1186/Gm247  0.57
2011 Navin N, Kendall J, Troge J, Andrews P, Rodgers L, McIndoo J, Cook K, Stepansky A, Levy D, Esposito D, Muthuswamy L, Krasnitz A, McCombie WR, Hicks J, Wigler M. Tumour evolution inferred by single-cell sequencing. Nature. 472: 90-4. PMID 21399628 DOI: 10.1038/Nature09807  0.463
2011 Navin NE, Hicks J. Corrigendum to "Tracing the tumor lineage" [Mol. Oncol. 4 (2010) 267-283] Molecular Oncology. 5: 302. DOI: 10.1016/J.Molonc.2011.01.008  0.38
2010 Navin NE, Hicks J. Tracing the tumor lineage. Molecular Oncology. 4: 267-83. PMID 20537601 DOI: 10.1016/J.Molonc.2010.04.010  0.495
2010 Navin N, Krasnitz A, Rodgers L, Cook K, Meth J, Kendall J, Riggs M, Eberling Y, Troge J, Grubor V, Levy D, Lundin P, MÃ¥nér S, Zetterberg A, Hicks J, et al. Inferring tumor progression from genomic heterogeneity. Genome Research. 20: 68-80. PMID 19903760 DOI: 10.1101/Gr.099622.109  0.514
2010 Hicks JB, Navin NE, Kendall JT, Levy D, Wigler MH. Tracing Tumor Lineage and Progression through Genomic Copy Number Profiling at the Single Cell Level Annals of Oncology. DOI: 10.1093/Annonc/Mdq145  0.495
2009 Grubor V, Krasnitz A, Troge JE, Meth JL, Lakshmi B, Kendall JT, Yamrom B, Alex G, Pai D, Navin N, Hufnagel LA, Lee YH, Cook K, Allen SL, Rai KR, et al. Novel genomic alterations and clonal evolution in chronic lymphocytic leukemia revealed by representational oligonucleotide microarray analysis (ROMA). Blood. 113: 1294-303. PMID 18922857 DOI: 10.1182/Blood-2008-05-158865  0.395
2008 Grubor V, Krasnitz A, Troge JE, Meth JL, Lakshmi B, Kendall JT, Yamrom B, Alex G, Pai D, Navin N, Hufnagel LA, Lee Y, Cook K, Allen SL, Rai KR, et al. High-Resolution Array-Based Comparative Genome Hybridization (CGH) Identifies Novel and Recurrent Regions in CLL. Blood. 112: 2058-2058. DOI: 10.1182/Blood.V112.11.2058.2058  0.356
2006 Pelham RJ, Rodgers L, Hall I, Lucito R, Nguyen KC, Navin N, Hicks J, Mu D, Powers S, Wigler M, Botstein D. Identification of alterations in DNA copy number in host stromal cells during tumor progression. Proceedings of the National Academy of Sciences of the United States of America. 103: 19848-53. PMID 17167050 DOI: 10.1073/Pnas.0609635104  0.46
2006 Hicks J, Krasnitz A, Lakshmi B, Navin NE, Riggs M, Leibu E, Esposito D, Alexander J, Troge J, Grubor V, Yoon S, Wigler M, Ye K, Børresen-Dale AL, Naume B, et al. Novel patterns of genome rearrangement and their association with survival in breast cancer. Genome Research. 16: 1465-79. PMID 17142309 DOI: 10.1101/Gr.5460106  0.484
2006 Navin N, Grubor V, Hicks J, Leibu E, Thomas E, Troge J, Riggs M, Lundin P, MÃ¥nér S, Sebat J, Zetterberg A, Wigler M. PROBER: oligonucleotide FISH probe design software. Bioinformatics (Oxford, England). 22: 2437-8. PMID 16740623 DOI: 10.1093/Bioinformatics/Btl273  0.4
2005 Hicks J, Muthuswamy L, Krasnitz A, Navin N, Riggs M, Grubor V, Esposito D, Alexander J, Troge J, Wigler M, Maner S, Lundin P, Zetterberg A. High-resolution ROMA CGH and FISH analysis of aneuploid and diploid breast tumors. Cold Spring Harbor Symposia On Quantitative Biology. 70: 51-63. PMID 16869738 DOI: 10.1101/Sqb.2005.70.055  0.479
2005 Hicks J, Grubor V, Navin N, Lundin P, Månér S, Hägerström T, Skoog L, Wigler M, Zetterberg A. High-resolution representational oligonucleotide microarray analysis and fluorescence in situ hybridization analysis of aneuploid and diploid breast tumors. Breast Cancer Research. 7: 1-1. DOI: 10.1186/Bcr1069  0.392
2004 Sebat J, Lakshmi B, Troge J, Alexander J, Young J, Lundin P, MÃ¥nér S, Massa H, Walker M, Chi M, Navin N, Lucito R, Healy J, Hicks J, Ye K, et al. Large-scale copy number polymorphism in the human genome. Science (New York, N.Y.). 305: 525-8. PMID 15273396 DOI: 10.1126/Science.1098918  0.35
2004 Thomas EE, Srebro N, Sebat J, Navin N, Healy J, Mishra B, Wigler M. Distribution of short paired duplications in mammalian genomes. Proceedings of the National Academy of Sciences of the United States of America. 101: 10349-54. PMID 15240876 DOI: 10.1073/Pnas.0403727101  0.367
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