Elaine Mardis, Ph.D. - Publications

Affiliations: 
University of Oklahoma, Norman, OK, United States 

181 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Griffith OL, Chan SR, Griffith M, Krysiak K, Skidmore ZL, Hundal J, Allen JA, Arthur CD, Runci D, Bugatti M, Miceli AP, Schmidt H, Trani L, Kanchi KL, Miller CA, ... ... Mardis ER, et al. Truncating Prolactin Receptor Mutations Promote Tumor Growth in Murine Estrogen Receptor-Alpha Mammary Carcinomas. Cell Reports. 17: 249-60. PMID 27681435 DOI: 10.1016/j.celrep.2016.08.076  0.68
2016 Miller CA, Gindin Y, Lu C, Griffith OL, Griffith M, Shen D, Hoog J, Li T, Larson DE, Watson M, Davies SR, Hunt K, Suman VJ, Snider J, Walsh T, ... ... Mardis ER, et al. Aromatase inhibition remodels the clonal architecture of estrogen-receptor-positive breast cancers. Nature Communications. 7: 12498. PMID 27502118 DOI: 10.1038/ncomms12498  0.68
2016 Griffith M, Griffith OL, Krysiak K, Skidmore ZL, Christopher MJ, Klco JM, Ramu A, Lamprecht TL, Wagner AH, Campbell KM, Lesurf R, Hundal J, Zhang J, Spies NC, Ainscough BJ, ... ... Mardis ER, et al. Comprehensive genomic analysis reveals FLT3 activation and a therapeutic strategy for a patient with relapsed adult B lymphoblastic leukemia. Experimental Hematology. PMID 27181063 DOI: 10.1016/j.exphem.2016.04.011  0.68
2016 Pfefferle AD, Agrawal YN, Koboldt DC, Kanchi KL, Herschkowitz JI, Mardis ER, Rosen JM, Perou CM. Genomic profiling of murine mammary tumors identifies potential personalized drug targets for p53 deficient mammary cancers. Disease Models & Mechanisms. PMID 27149990 DOI: 10.1242/dmm.025239  0.68
2016 Liu C, Yang W, Devidas M, Cheng C, Pei D, Smith C, Carroll WL, Raetz EA, Bowman WP, Larsen EC, Maloney KW, Martin PL, Mattano LA, Winick NJ, Mardis ER, et al. Clinical and Genetic Risk Factors for Acute Pancreatitis in Patients With Acute Lymphoblastic Leukemia. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. PMID 27114598 DOI: 10.1200/JCO.2015.64.5812  0.68
2016 Hundal J, Carreno BM, Petti AA, Linette GP, Griffith OL, Mardis ER, Griffith M. pVAC-Seq: A genome-guided in silico approach to identifying tumor neoantigens. Genome Medicine. 8: 11. PMID 26825632 DOI: 10.1186/s13073-016-0264-5  0.68
2016 Qaddoumi I, Orisme W, Wen J, Santiago T, Gupta K, Dalton JD, Tang B, Haupfear K, Punchihewa C, Easton J, Mulder H, Boggs K, Shao Y, Rusch M, Becksfort J, ... ... Mardis ER, et al. Genetic alterations in uncommon low-grade neuroepithelial tumors: BRAF, FGFR1, and MYB mutations occur at high frequency and align with morphology. Acta Neuropathologica. PMID 26810070 DOI: 10.1007/s00401-016-1539-z  0.68
2016 Gordon AS, Fulton RS, Qin X, Mardis ER, Nickerson DA, Scherer S. PGRNseq: a targeted capture sequencing panel for pharmacogenetic research and implementation. Pharmacogenetics and Genomics. PMID 26736087 DOI: 10.1097/FPC.0000000000000202  0.68
2015 Mardis E. Cancer Genomics. F1000research. 4. PMID 26937274 DOI: 10.12688/f1000research.6645.1  0.68
2015 Wong TN, Miller CA, Klco JM, Petti A, Demeter R, Helton NM, Li T, Fulton RS, Heath SE, Mardis ER, Westervelt P, DiPersio JF, Walter MJ, Welch JS, Graubert TA, et al. Rapid expansion of pre-existing non-leukemic hematopoietic clones frequently follows induction therapy for de novo AML. Blood. PMID 26631115 DOI: 10.1182/blood-2015-10-677021  0.68
2015 Karol SE, Mattano LA, Yang W, Maloney KW, Smith C, Liu C, Ramsey LB, Fernandez CA, Chang TY, Neale G, Cheng C, Mardis E, Fulton R, Scheet P, San Lucas FA, et al. Genetic risk factors for the development of osteonecrosis in children under age 10 treated for acute lymphoblastic leukemia. Blood. PMID 26590194 DOI: 10.1182/blood-2015-10-673848  0.68
2015 Solga AC, Pong WW, Kim KY, Cimino PJ, Toonen JA, Walker J, Wylie T, Magrini V, Griffith M, Griffith OL, Ly A, Ellisman MH, Mardis ER, Gutmann DH. RNA Sequencing of Tumor-Associated Microglia Reveals Ccl5 as a Stromal Chemokine Critical for Neurofibromatosis-1 Glioma Growth. Neoplasia (New York, N.Y.). 17: 776-88. PMID 26585233 DOI: 10.1016/j.neo.2015.10.002  0.68
2015 Wagner AH, Coffman AC, Ainscough BJ, Spies NC, Skidmore ZL, Campbell KM, Krysiak K, Pan D, McMichael JF, Eldred JM, Walker JR, Wilson RK, Mardis ER, Griffith M, Griffith OL. DGIdb 2.0: mining clinically relevant drug-gene interactions. Nucleic Acids Research. PMID 26531824 DOI: 10.1093/nar/gkv1165  0.68
2015 Rastogi S, Borgo B, Pazdernik N, Fox P, Mardis ER, Kohara Y, Havranek J, Schedl T. Caenorhabditis elegans glp-4 Encodes a Valyl Aminoacyl tRNA Synthetase. G3 (Bethesda, Md.). PMID 26464357 DOI: 10.1534/g3.115.021899  0.68
2015 Klco JM, Miller CA, Griffith M, Petti A, Spencer DH, Ketkar-Kulkarni S, Wartman LD, Christopher M, Lamprecht TL, Helton NM, Duncavage EJ, Payton JE, Baty J, Heath SE, Griffith OL, ... ... Mardis ER, et al. Association Between Mutation Clearance After Induction Therapy and Outcomes in Acute Myeloid Leukemia. Jama. 314: 811-22. PMID 26305651 DOI: 10.1001/jama.2015.9643  0.68
2015 Wallden B, Storhoff J, Nielsen T, Dowidar N, Schaper C, Ferree S, Liu S, Leung S, Geiss G, Snider J, Vickery T, Davies SR, Mardis ER, Gnant M, Sestak I, et al. Development and verification of the PAM50-based Prosigna breast cancer gene signature assay. Bmc Medical Genomics. 8: 54. PMID 26297356 DOI: 10.1186/s12920-015-0129-6  0.68
2015 Gubin MM, Artyomov MN, Mardis ER, Schreiber RD. Tumor neoantigens: building a framework for personalized cancer immunotherapy. The Journal of Clinical Investigation. 125: 3413-21. PMID 26258412 DOI: 10.1172/JCI80008  0.68
2015 Tyler-Smith C, Yang H, Landweber LF, Dunham I, Knoppers BM, Donnelly P, Mardis ER, Snyder M, McVean G. Where Next for Genetics and Genomics? Plos Biology. 13: e1002216. PMID 26225775 DOI: 10.1371/journal.pbio.1002216  0.68
2015 Griffith M, Griffith OL, Smith SM, Ramu A, Callaway MB, Brummett AM, Kiwala MJ, Coffman AC, Regier AA, Oberkfell BJ, Sanderson GE, Mooney TP, Nutter NG, Belter EA, Du F, ... ... Mardis ER, et al. Genome Modeling System: A Knowledge Management Platform for Genomics. Plos Computational Biology. 11: e1004274. PMID 26158448 DOI: 10.1371/journal.pcbi.1004274  0.68
2015 Meltz Steinberg K, Nicholas TJ, Koboldt DC, Yu B, Mardis E, Pamphlett R. Whole genome analyses reveal no pathogenetic single nucleotide or structural differences between monozygotic twins discordant for amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. 1-8. PMID 25960086 DOI: 10.3109/21678421.2015.1040029  0.68
2015 Diogo D, Bastarache L, Liao KP, Graham RR, Fulton RS, Greenberg JD, Eyre S, Bowes J, Cui J, Lee A, Pappas DA, Kremer JM, Barton A, Coenen MJ, Franke B, ... ... Mardis ER, et al. TYK2 protein-coding variants protect against rheumatoid arthritis and autoimmunity, with no evidence of major pleiotropic effects on non-autoimmune complex traits. Plos One. 10: e0122271. PMID 25849893 DOI: 10.1371/journal.pone.0122271  0.68
2015 Steinberg KM, Yu B, Koboldt DC, Mardis ER, Pamphlett R. Exome sequencing of case-unaffected-parents trios reveals recessive and de novo genetic variants in sporadic ALS. Scientific Reports. 5: 9124. PMID 25773295 DOI: 10.1038/srep09124  0.68
2015 Pinto EM, Chen X, Easton J, Finkelstein D, Liu Z, Pounds S, Rodriguez-Galindo C, Lund TC, Mardis ER, Wilson RK, Boggs K, Yergeau D, Cheng J, Mulder HL, Manne J, et al. Genomic landscape of paediatric adrenocortical tumours. Nature Communications. 6: 6302. PMID 25743702 DOI: 10.1038/ncomms7302  0.68
2015 Mardis ER. Xenografts as models of clonal selection and acquired resistance to therapy Clinical Chemistry. 61: 769-770. PMID 25733716 DOI: 10.1373/clinchem.2014.237289  0.68
2015 Andersson AK, Ma J, Wang J, Chen X, Gedman AL, Dang J, Nakitandwe J, Holmfeldt L, Parker M, Easton J, Huether R, Kriwacki R, Rusch M, Wu G, Li Y, ... ... Mardis ER, et al. The landscape of somatic mutations in infant MLL-rearranged acute lymphoblastic leukemias. Nature Genetics. 47: 330-7. PMID 25730765 DOI: 10.1038/ng.3230  0.68
2015 Chalivendra V, Kanchi KL, Onken MD, Winkler AE, Mardis E, Uppaluri R. Genomic analysis to define molecular basis of aggressiveness in a mouse model of oral cancer. Genomics Data. 3: 61-62. PMID 25729643 DOI: 10.1016/j.gdata.2014.11.006  0.68
2015 Wong TN, Ramsingh G, Young AL, Miller CA, Touma W, Welch JS, Lamprecht TL, Shen D, Hundal J, Fulton RS, Heath S, Baty JD, Klco JM, Ding L, Mardis ER, et al. Role of TP53 mutations in the origin and evolution of therapy-related acute myeloid leukaemia. Nature. 518: 552-5. PMID 25487151 DOI: 10.1038/nature13968  0.68
2015 Juric D, Castel P, Griffith M, Griffith OL, Won HH, Ellis H, Ebbesen SH, Ainscough BJ, Ramu A, Iyer G, Shah RH, Huynh T, Mino-Kenudson M, Sgroi D, Isakoff S, ... ... Mardis ER, et al. Convergent loss of PTEN leads to clinical resistance to a PI(3)Kα inhibitor. Nature. 518: 240-4. PMID 25409150 DOI: 10.1038/nature13948  0.68
2015 Lu C, Zhang J, Nagahawatte P, Easton J, Lee S, Liu Z, Ding L, Wyczalkowski MA, Valentine M, Navid F, Mulder H, Tatevossian RG, Dalton J, Davenport J, Yin Z, ... ... Mardis ER, et al. The genomic landscape of childhood and adolescent melanoma. The Journal of Investigative Dermatology. 135: 816-23. PMID 25268584 DOI: 10.1038/jid.2014.425  0.68
2015 Solga AC, Pong WW, Walker J, Wylie T, Magrini V, Apicelli AJ, Griffith M, Griffith OL, Kohsaka S, Wu GF, Brody DL, Mardis ER, Gutmann DH. RNA-sequencing reveals oligodendrocyte and neuronal transcripts in microglia relevant to central nervous system disease. Glia. 63: 531-48. PMID 25258010 DOI: 10.1002/glia.22754  0.68
2015 Mardis E. Next-generation sequencing, cancer and molecular diagnostics: An interview with Elaine Mardis Expert Review of Molecular Diagnostics. 15: 449-450. DOI: 10.1586/14737159.2015.1030144  0.68
2015 Auton A, Abecasis GR, Altshuler DM, Durbin RM, Bentley DR, Chakravarti A, Clark AG, Donnelly P, Eichler EE, Flicek P, Gabriel SB, Gibbs RA, Green ED, Hurles ME, Knoppers BM, ... ... Mardis ER, et al. A global reference for human genetic variation Nature. 526: 68-74. DOI: 10.1038/nature15393  0.68
2015 Griffith M, Miller CA, Griffith OL, Krysiak K, Skidmore ZL, Ramu A, Walker JR, Dang HX, Trani L, Larson DE, Demeter RT, Wendl MC, McMichael JF, Austin RE, Magrini V, ... ... Mardis ER, et al. Optimizing Cancer Genome Sequencing and Analysis Cell Systems. 1: 210-223. DOI: 10.1016/j.cels.2015.08.015  0.48
2014 Lopatto D, Hauser C, Jones CJ, Paetkau D, Chandrasekaran V, Dunbar D, MacKinnon C, Stamm J, Alvarez C, Barnard D, Bedard JE, Bednarski AE, Bhalla S, Braverman JM, Burg M, ... ... Mardis E, et al. A central support system can facilitate implementation and sustainability of a Classroom-based Undergraduate Research Experience (CURE) in Genomics. Cbe Life Sciences Education. 13: 711-23. PMID 25452493 DOI: 10.1187/cbe.13-10-0200  0.68
2014 Jorns JM, Thomas DG, Healy PN, Daignault S, Vickery TL, Snider JE, Mardis ER, Davies SR, Ellis MJ, Visscher DW. Estrogen receptor expression is high but is of lower intensity in tubular carcinoma than in well-differentiated invasive ductal carcinoma. Archives of Pathology & Laboratory Medicine. 138: 1507-13. PMID 25357113 DOI: 10.5858/arpa.2013-0621-OA  0.68
2014 Xie M, Lu C, Wang J, McLellan MD, Johnson KJ, Wendl MC, McMichael JF, Schmidt HK, Yellapantula V, Miller CA, Ozenberger BA, Welch JS, Link DC, Walter MJ, Mardis ER, et al. Age-related mutations associated with clonal hematopoietic expansion and malignancies. Nature Medicine. 20: 1472-8. PMID 25326804 DOI: 10.1038/nm.3733  0.68
2014 Arteaga CL, Adamson PC, Engelman JA, Foti M, Gaynor RB, Hilsenbeck SG, Limburg PJ, Lowe SW, Mardis ER, Ramsey S, Rebbeck TR, Richardson AL, Rubin EH, Weiner GJ. AACR Cancer Progress Report 2014. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 20: S1-S112. PMID 25228531 DOI: 10.1158/1078-0432.CCR-14-2123  0.68
2014 Tirode F, Surdez D, Ma X, Parker M, Le Deley MC, Bahrami A, Zhang Z, Lapouble E, Grossetête-Lalami S, Rusch M, Reynaud S, Rio-Frio T, Hedlund E, Wu G, Chen X, ... ... Mardis ER, et al. Genomic landscape of Ewing sarcoma defines an aggressive subtype with co-association of STAG2 and TP53 mutations. Cancer Discovery. 4: 1342-53. PMID 25223734 DOI: 10.1158/2159-8290.CD-14-0622  0.68
2014 Liu Y, Patel L, Mills GB, Lu KH, Sood AK, Ding L, Kucherlapati R, Mardis ER, Levine DA, Shmulevich I, Broaddus RR, Zhang W. Clinical significance of CTNNB1 mutation and Wnt pathway activation in endometrioid endometrial carcinoma. Journal of the National Cancer Institute. 106. PMID 25214561 DOI: 10.1093/jnci/dju245  0.68
2014 Roberts KG, Li Y, Payne-Turner D, Harvey RC, Yang YL, Pei D, McCastlain K, Ding L, Lu C, Song G, Ma J, Becksfort J, Rusch M, Chen SC, Easton J, ... ... Mardis E, et al. Targetable kinase-activating lesions in Ph-like acute lymphoblastic leukemia. The New England Journal of Medicine. 371: 1005-15. PMID 25207766 DOI: 10.1056/NEJMoa1403088  0.68
2014 Miller CA, White BS, Dees ND, Griffith M, Welch JS, Griffith OL, Vij R, Tomasson MH, Graubert TA, Walter MJ, Ellis MJ, Schierding W, DiPersio JF, Ley TJ, Mardis ER, et al. SciClone: inferring clonal architecture and tracking the spatial and temporal patterns of tumor evolution. Plos Computational Biology. 10: e1003665. PMID 25102416 DOI: 10.1371/journal.pcbi.1003665  0.68
2014 . Comprehensive molecular profiling of lung adenocarcinoma. Nature. 511: 543-50. PMID 25079552 DOI: 10.1038/nature13385  0.48
2014 Cabanski CR, Magrini V, Griffith M, Griffith OL, McGrath S, Zhang J, Walker J, Ly A, Demeter R, Fulton RS, Pong WW, Gutmann DH, Govindan R, Mardis ER, Maher CA. cDNA hybrid capture improves transcriptome analysis on low-input and archived samples. The Journal of Molecular Diagnostics : Jmd. 16: 440-51. PMID 24814956 DOI: 10.1016/j.jmoldx.2014.03.004  0.68
2014 Huether R, Dong L, Chen X, Wu G, Parker M, Wei L, Ma J, Edmonson MN, Hedlund EK, Rusch MC, Shurtleff SA, Mulder HL, Boggs K, Vadordaria B, Cheng J, ... ... Mardis ER, et al. The landscape of somatic mutations in epigenetic regulators across 1,000 paediatric cancer genomes. Nature Communications. 5: 3630. PMID 24710217 DOI: 10.1038/ncomms4630  0.68
2014 Wu G, Diaz AK, Paugh BS, Rankin SL, Ju B, Li Y, Zhu X, Qu C, Chen X, Zhang J, Easton J, Edmonson M, Ma X, Lu C, Nagahawatte P, ... ... Mardis ER, et al. The genomic landscape of diffuse intrinsic pontine glioma and pediatric non-brainstem high-grade glioma. Nature Genetics. 46: 444-50. PMID 24705251 DOI: 10.1038/ng.2938  0.68
2014 Chen X, Bahrami A, Pappo A, Easton J, Dalton J, Hedlund E, Ellison D, Shurtleff S, Wu G, Wei L, Parker M, Rusch M, Nagahawatte P, Wu J, Mao S, ... ... Mardis ER, et al. Recurrent somatic structural variations contribute to tumorigenesis in pediatric osteosarcoma. Cell Reports. 7: 104-12. PMID 24703847 DOI: 10.1016/j.celrep.2014.03.003  0.68
2014 Onken MD, Winkler AE, Kanchi KL, Chalivendra V, Law JH, Rickert CG, Kallogjeri D, Judd NP, Dunn GP, Piccirillo JF, Lewis JS, Mardis ER, Uppaluri R. A surprising cross-species conservation in the genomic landscape of mouse and human oral cancer identifies a transcriptional signature predicting metastatic disease. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 20: 2873-84. PMID 24668645 DOI: 10.1158/1078-0432.CCR-14-0205  0.68
2014 Wang C, Zhan X, Bragg-Gresham J, Kang HM, Stambolian D, Chew EY, Branham KE, Heckenlively J, Fulton R, Wilson RK, Mardis ER, Lin X, Swaroop A, Zöllner S, Abecasis GR. Ancestry estimation and control of population stratification for sequence-based association studies Nature Genetics. 46: 409-415. PMID 24633160 DOI: 10.1038/ng.2924  0.68
2014 Klco JM, Spencer DH, Miller CA, Griffith M, Lamprecht TL, O'Laughlin M, Fronick C, Magrini V, Demeter RT, Fulton RS, Eades WC, Link DC, Graubert TA, Walter MJ, Mardis ER, et al. Functional heterogeneity of genetically defined subclones in acute myeloid leukemia. Cancer Cell. 25: 379-92. PMID 24613412 DOI: 10.1016/j.ccr.2014.01.031  0.68
2014 Shaffer CD, Alvarez CJ, Bednarski AE, Dunbar D, Goodman AL, Reinke C, Rosenwald AG, Wolyniak MJ, Bailey C, Barnard D, Bazinet C, Beach DL, Bedard JE, Bhalla S, Braverman J, ... ... Mardis ER, et al. A course-based research experience: how benefits change with increased investment in instructional time. Cbe Life Sciences Education. 13: 111-30. PMID 24591510 DOI: 10.1187/cbe-13-08-0152  0.68
2014 Weeke P, Mosley JD, Hanna D, Delaney JT, Shaffer C, Wells QS, Van Driest S, Karnes JH, Ingram C, Guo Y, Shyr Y, Norris K, Kannankeril PJ, Ramirez AH, Smith JD, ... Mardis ER, et al. Exome sequencing implicates an increased burden of rare potassium channel variants in the risk of drug-induced long QT interval syndrome. Journal of the American College of Cardiology. 63: 1430-7. PMID 24561134 DOI: 10.1016/j.jacc.2014.01.031  0.68
2014 Parker M, Mohankumar KM, Punchihewa C, Weinlich R, Dalton JD, Li Y, Lee R, Tatevossian RG, Phoenix TN, Thiruvenkatam R, White E, Tang B, Orisme W, Gupta K, Rusch M, ... ... Mardis ER, et al. C11orf95-RELA fusions drive oncogenic NF-κB signalling in ependymoma. Nature. 506: 451-5. PMID 24553141 DOI: 10.1038/nature13109  0.68
2014 Okada Y, Diogo D, Greenberg JD, Mouassess F, Achkar WA, Fulton RS, Denny JC, Gupta N, Mirel D, Gabriel S, Li G, Kremer JM, Pappas DA, Carroll RJ, Eyler AE, ... ... Mardis ER, et al. Integration of sequence data from a Consanguineous family with genetic data from an outbred population identifies PLB1 as a candidate rheumatoid arthritis risk gene. Plos One. 9: e87645. PMID 24520335 DOI: 10.1371/journal.pone.0087645  0.68
2014 McEvoy J, Nagahawatte P, Finkelstein D, Richards-Yutz J, Valentine M, Ma J, Mullighan C, Song G, Chen X, Wilson M, Brennan R, Pounds S, Becksfort J, Huether R, Lu C, ... ... Mardis ER, et al. RB1 gene inactivation by chromothripsis in human retinoblastoma. Oncotarget. 5: 438-50. PMID 24509483  0.48
2014 Kanchi KL, Johnson KJ, Lu C, McLellan MD, Leiserson MD, Wendl MC, Zhang Q, Koboldt DC, Xie M, Kandoth C, McMichael JF, Wyczalkowski MA, Larson DE, Schmidt HK, Miller CA, ... ... Mardis ER, et al. Integrated analysis of germline and somatic variants in ovarian cancer. Nature Communications. 5: 3156. PMID 24448499 DOI: 10.1038/ncomms4156  0.68
2014 Gronowski AM, Manson JE, Mardis ER, Mora S, Spong CY. What's different about women's health? Clinical Chemistry. 60: 1-3. DOI: 10.1373/clinchem.2013.216598  0.68
2014 Mardis E. Revolutionizing cancer care with next-generation sequencing: An interview with Elaine Mardis Dmm Disease Models and Mechanisms. 7: 313-317. DOI: 10.1242/dmm.015396  0.68
2014 Aparicio S, Mardis E. Tumor heterogeneity: Next-generation sequencing enhances the view from the pathologist's microscope Genome Biology. 15. DOI: 10.1186/s13059-014-0463-6  0.68
2014 Mardis ER. The translation of cancer genomics: Time for a revolution in clinical cancer care Genome Medicine. 6. DOI: 10.1186/gm539  0.68
2014 Mardis ER. Sequencing the AML Genome, Transcriptome, and Epigenome Seminars in Hematology. 51: 250-258. DOI: 10.1053/j.seminhematol.2014.08.003  0.68
2014 Mardis ER. The Technology of Analyzing Nucleic Acids in Cancer The Molecular Basis of Cancer: Fourth Edition. 347-356.e1. DOI: 10.1016/B978-1-4557-4066-6.00023-8  0.68
2014 McEvoy J, Nagahawatte P, Finkelstein D, Richards-Yutz J, Valentine M, Ma J, Mullighan C, Song G, Chen X, Wilson M, Brennan R, Pounds S, Becksfort J, Huether R, Lu C, ... ... Mardis ER, et al. RB1 gene inactivation by chromothripsis in human retinoblastoma Oncotarget. 5: 438-450.  0.68
2013 Chen X, Stewart E, Shelat AA, Qu C, Bahrami A, Hatley M, Wu G, Bradley C, McEvoy J, Pappo A, Spunt S, Valentine MB, Valentine V, Krafcik F, Lang WH, ... ... Mardis ER, et al. Targeting oxidative stress in embryonal rhabdomyosarcoma. Cancer Cell. 24: 710-24. PMID 24332040 DOI: 10.1016/j.ccr.2013.11.002  0.68
2013 Pong WW, Walker J, Wylie T, Magrini V, Luo J, Emnett RJ, Choi J, Cooper ML, Griffith M, Griffith OL, Rubin JB, Fuller GN, Piwnica-Worms D, Feng X, Hambardzumyan D, ... ... Mardis ER, et al. F11R is a novel monocyte prognostic biomarker for malignant glioma. Plos One. 8: e77571. PMID 24147027 DOI: 10.1371/journal.pone.0077571  0.68
2013 Griffith M, Griffith OL, Coffman AC, Weible JV, McMichael JF, Spies NC, Koval J, Das I, Callaway MB, Eldred JM, Miller CA, Subramanian J, Govindan R, Kumar RD, Bose R, ... ... Mardis ER, et al. DGIdb: mining the druggable genome. Nature Methods. 10: 1209-10. PMID 24122041 DOI: 10.1038/nmeth.2689  0.68
2013 Koboldt DC, Steinberg KM, Larson DE, Wilson RK, Mardis ER. The next-generation sequencing revolution and its impact on genomics. Cell. 155: 27-38. PMID 24074859 DOI: 10.1016/j.cell.2013.09.006  0.68
2013 Li S, Shen D, Shao J, Crowder R, Liu W, Prat A, He X, Liu S, Hoog J, Lu C, Ding L, Griffith OL, Miller C, Larson D, Fulton RS, ... ... Mardis ER, et al. Endocrine-therapy-resistant ESR1 variants revealed by genomic characterization of breast-cancer-derived xenografts. Cell Reports. 4: 1116-30. PMID 24055055 DOI: 10.1016/j.celrep.2013.08.022  0.68
2013 Sawyers CL, Abate-Shen C, Anderson KC, Barker A, Baselga J, Berger NA, Foti M, Jemal A, Lawrence TS, Li CI, Mardis ER, Neumann PJ, Pardoll DM, Prendergast GC, et al. AACR Cancer Progress Report 2013. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 19: S4-98. PMID 24045178 DOI: 10.1158/1078-0432.CCR-13-2107  0.68
2013 Zhan X, Larson DE, Wang C, Koboldt DC, Sergeev YV, Fulton RS, Fulton LL, Fronick CC, Branham KE, Bragg-Gresham J, Jun G, Hu Y, Kang HM, Liu D, Othman M, ... ... Mardis ER, et al. Identification of a rare coding variant in complement 3 associated with age-related macular degeneration. Nature Genetics. 45: 1375-9. PMID 24036949 DOI: 10.1038/ng.2758  0.68
2013 Chen K, Navin NE, Wang Y, Schmidt HK, Wallis JW, Niu B, Fan X, Zhao H, McLellan MD, Hoadley KA, Mardis ER, Ley TJ, Perou CM, Wilson RK, Ding L. BreakTrans: uncovering the genomic architecture of gene fusions. Genome Biology. 14: R87. PMID 23972288 DOI: 10.1186/gb-2013-14-8-r87  0.68
2013 Zhang J, Wu G, Miller CP, Tatevossian RG, Dalton JD, Tang B, Orisme W, Punchihewa C, Parker M, Qaddoumi I, Boop FA, Lu C, Kandoth C, Ding L, Lee R, ... ... Mardis ER, et al. Whole-genome sequencing identifies genetic alterations in pediatric low-grade gliomas. Nature Genetics. 45: 602-12. PMID 23583981 DOI: 10.1038/ng.2611  0.68
2013 Mardis ER. Next-generation sequencing platforms Annual Review of Analytical Chemistry. 6: 287-303. PMID 23560931 DOI: 10.1146/annurev-anchem-062012-092628  0.68
2013 Shaffer HB, Minx P, Warren DE, Shedlock AM, Thomson RC, Valenzuela N, Abramyan J, Amemiya CT, Badenhorst D, Biggar KK, Borchert GM, Botka CW, Bowden RM, Braun EL, Bronikowski AM, ... ... Mardis ER, et al. The western painted turtle genome, a model for the evolution of extreme physiological adaptations in a slowly evolving lineage. Genome Biology. 14: R28. PMID 23537068 DOI: 10.1186/gb-2013-14-3-r28  0.68
2013 Walter MJ, Shen D, Shao J, Ding L, White BS, Kandoth C, Miller CA, Niu B, McLellan MD, Dees ND, Fulton R, Elliot K, Heath S, Grillot M, Westervelt P, ... ... Mardis E, et al. Clonal diversity of recurrently mutated genes in myelodysplastic syndromes. Leukemia. 27: 1275-82. PMID 23443460 DOI: 10.1038/leu.2013.58  0.68
2013 Gelb B, Brueckner M, Chung W, Goldmuntz E, Kaltman J, Kaski JP, Kim R, Kline J, Mercer-Rosa L, Porter G, Roberts A, Rosenberg E, Seiden H, Seidman C, et al. The Congenital Heart Disease Genetic Network Study: rationale, design, and early results. Circulation Research. 112: 698-706. PMID 23410879 DOI: 10.1161/CIRCRESAHA.111.300297  0.68
2013 Swart EC, Bracht JR, Magrini V, Minx P, Chen X, Zhou Y, Khurana JS, Goldman AD, Nowacki M, Schotanus K, Jung S, Fulton RS, Ly A, McGrath S, Haub K, ... ... Mardis ER, et al. The Oxytricha trifallax macronuclear genome: a complex eukaryotic genome with 16,000 tiny chromosomes. Plos Biology. 11: e1001473. PMID 23382650 DOI: 10.1371/journal.pbio.1001473  0.68
2013 Holmfeldt L, Wei L, Diaz-Flores E, Walsh M, Zhang J, Ding L, Payne-Turner D, Churchman M, Andersson A, Chen SC, McCastlain K, Becksfort J, Ma J, Wu G, Patel SN, ... ... Mardis ER, et al. The genomic landscape of hypodiploid acute lymphoblastic leukemia. Nature Genetics. 45: 242-52. PMID 23334668 DOI: 10.1038/ng.2532  0.68
2013 Klco JM, Spencer DH, Lamprecht TL, Sarkaria SM, Wylie T, Magrini V, Hundal J, Walker J, Varghese N, Erdmann-Gilmore P, Lichti CF, Meyer MR, Townsend RR, Wilson RK, Mardis ER, et al. Genomic impact of transient low-dose decitabine treatment on primary AML cells. Blood. 121: 1633-43. PMID 23297133 DOI: 10.1182/blood-2012-09-459313  0.68
2013 Gutmann DH, McLellan MD, Hussain I, Wallis JW, Fulton LL, Fulton RS, Magrini V, Demeter R, Wylie T, Kandoth C, Leonard JR, Guha A, Miller CA, Ding L, Mardis ER. Somatic neurofibromatosis type 1 (NF1) inactivation characterizes NF1-associated pilocytic astrocytoma. Genome Research. 23: 431-9. PMID 23222849 DOI: 10.1101/gr.142604.112  0.68
2013 Bose R, Kavuri SM, Searleman AC, Shen W, Shen D, Koboldt DC, Monsey J, Goel N, Aronson AB, Li S, Ma CX, Ding L, Mardis ER, Ellis MJ. Activating HER2 mutations in HER2 gene amplification negative breast cancer. Cancer Discovery. 3: 224-37. PMID 23220880 DOI: 10.1158/2159-8290.CD-12-0349  0.68
2013 Mardis ER. Whole-Genome Sequencing: New Technologies, Approaches, and Applications Genomic and Personalized Medicine. 1: 87-93. DOI: 10.1016/B978-0-12-382227-7.00007-0  0.68
2012 Parker M, Chen X, Bahrami A, Dalton J, Rusch M, Wu G, Easton J, Cheung NK, Dyer M, Mardis ER, Wilson RK, Mullighan C, Gilbertson R, Baker SJ, Zambetti G, et al. Assessing telomeric DNA content in pediatric cancers using whole-genome sequencing data. Genome Biology. 13: R113. PMID 23232254 DOI: 10.1186/gb-2012-13-12-r113  0.68
2012 Gruber TA, Larson Gedman A, Zhang J, Koss CS, Marada S, Ta HQ, Chen SC, Su X, Ogden SK, Dang J, Wu G, Gupta V, Andersson AK, Pounds S, Shi L, ... ... Mardis ER, et al. An Inv(16)(p13.3q24.3)-encoded CBFA2T3-GLIS2 fusion protein defines an aggressive subtype of pediatric acute megakaryoblastic leukemia. Cancer Cell. 22: 683-97. PMID 23153540 DOI: 10.1016/j.ccr.2012.10.007  0.68
2012 Gargis AS, Kalman L, Berry MW, Bick DP, Dimmock DP, Hambuch T, Lu F, Lyon E, Voelkerding KV, Zehnbauer BA, Agarwala R, Bennett SF, Chen B, Chin EL, Compton JG, ... ... Mardis ER, et al. Assuring the quality of next-generation sequencing in clinical laboratory practice. Nature Biotechnology. 30: 1033-6. PMID 23138292 DOI: 10.1038/nbt.2403  0.68
2012 Abecasis GR, Auton A, Brooks LD, DePristo MA, Durbin RM, Handsaker RE, Kang HM, Marth GT, McVean GA. An integrated map of genetic variation from 1,092 human genomes. Nature. 491: 56-65. PMID 23128226 DOI: 10.1038/nature11632  0.68
2012 Govindan R, Ding L, Griffith M, Subramanian J, Dees ND, Kanchi KL, Maher CA, Fulton R, Fulton L, Wallis J, Chen K, Walker J, McDonald S, Bose R, Ornitz D, ... ... Mardis ER, et al. Genomic landscape of non-small cell lung cancer in smokers and never-smokers. Cell. 150: 1121-34. PMID 22980976 DOI: 10.1016/j.cell.2012.08.024  0.68
2012 Welch JS, Ley TJ, Link DC, Miller CA, Larson DE, Koboldt DC, Wartman LD, Lamprecht TL, Liu F, Xia J, Kandoth C, Fulton RS, McLellan MD, Dooling DJ, Wallis JW, ... ... Mardis ER, et al. The origin and evolution of mutations in acute myeloid leukemia. Cell. 150: 264-78. PMID 22817890 DOI: 10.1016/j.cell.2012.06.023  0.68
2012 Muzny DM, Bainbridge MN, Chang K, Dinh HH, Drummond JA, Fowler G, Kovar CL, Lewis LR, Morgan MB, Newsham IF, Reid JG, Santibanez J, Shinbrot E, Trevino LR, Wu YQ, ... ... Mardis ER, et al. Comprehensive molecular characterization of human colon and rectal cancer Nature. 487: 330-337. PMID 22810696 DOI: 10.1038/nature11252  0.68
2012 Dees ND, Zhang Q, Kandoth C, Wendl MC, Schierding W, Koboldt DC, Mooney TB, Callaway MB, Dooling D, Mardis ER, Wilson RK, Ding L. MuSiC: Identifying mutational significance in cancer genomes Genome Research. 22: 1589-1598. PMID 22759861 DOI: 10.1101/gr.134635.111  0.68
2012 Mardis ER. Applying next-generation sequencing to pancreatic cancer treatment Nature Reviews Gastroenterology and Hepatology. 9: 477-486. PMID 22751458 DOI: 10.1038/nrgastro.2012.126  0.68
2012 Robinson G, Parker M, Kranenburg TA, Lu C, Chen X, Ding L, Phoenix TN, Hedlund E, Wei L, Zhu X, Chalhoub N, Baker SJ, Huether R, Kriwacki R, Curley N, ... ... Mardis ER, et al. Novel mutations target distinct subgroups of medulloblastoma. Nature. 488: 43-8. PMID 22722829 DOI: 10.1038/nature11213  0.68
2012 Ward DV, Gevers D, Giannoukos G, Earl AM, Methé BA, Sodergren E, Feldgarden M, Ciulla DM, Tabbaa D, Arze C, Appelbaum E, Aird L, Anderson S, Ayvaz T, Belter E, ... ... Mardis E, et al. Evaluation of 16s rDNA-based community profiling for human microbiome research Plos One. 7. PMID 22720093 DOI: 10.1371/journal.pone.0039315  0.68
2012 Chia SK, Bramwell VH, Tu D, Shepherd LE, Jiang S, Vickery T, Mardis E, Leung S, Ung K, Pritchard KI, Parker JS, Bernard PS, Perou CM, Ellis MJ, Nielsen TO. A 50-gene intrinsic subtype classifier for prognosis and prediction of benefit from adjuvant tamoxifen. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 18: 4465-72. PMID 22711706 DOI: 10.1158/1078-0432.CCR-12-0286  0.68
2012 McDonald SA, Mardis ER, Ota D, Watson MA, Pfeifer JD, Green JM. Comprehensive genomic studies: emerging regulatory, strategic, and quality assurance challenges for biorepositories. American Journal of Clinical Pathology. 138: 31-41. PMID 22706855 DOI: 10.1309/AJCPXBA69LNSCVMH  0.68
2012 Downing JR, Wilson RK, Zhang J, Mardis ER, Pui CH, Ding L, Ley TJ, Evans WE. The Pediatric Cancer Genome Project. Nature Genetics. 44: 619-22. PMID 22641210 DOI: 10.1038/ng.2287  0.68
2012 Chen K, Wallis JW, Kandoth C, Kalicki-Veizer JM, Mungall KL, Mungall AJ, Jones SJ, Marra MA, Ley TJ, Mardis ER, Wilson RK, Weinstein JN, Ding L. BreakFusion: targeted assembly-based identification of gene fusions in whole transcriptome paired-end sequencing data. Bioinformatics (Oxford, England). 28: 1923-4. PMID 22563071 DOI: 10.1093/bioinformatics/bts272  0.68
2012 Iossifov I, Ronemus M, Levy D, Wang Z, Hakker I, Rosenbaum J, Yamrom B, Lee YH, Narzisi G, Leotta A, Kendall J, Grabowska E, Ma B, Marks S, Rodgers L, ... ... Mardis ER, et al. De novo gene disruptions in children on the autistic spectrum. Neuron. 74: 285-99. PMID 22542183 DOI: 10.1016/j.neuron.2012.04.009  0.68
2012 Young MA, Larson DE, Sun CW, George DR, Ding L, Miller CA, Lin L, Pawlik KM, Chen K, Fan X, Schmidt H, Kalicki-Veizer J, Cook LL, Swift GW, Demeter RT, ... ... Mardis ER, et al. Background mutations in parental cells account for most of the genetic heterogeneity of induced pluripotent stem cells. Cell Stem Cell. 10: 570-82. PMID 22542160 DOI: 10.1016/j.stem.2012.03.002  0.68
2012 Mardis ER. Genome sequencing and cancer Current Opinion in Genetics and Development. 22: 245-250. PMID 22534183 DOI: 10.1016/j.gde.2012.03.005  0.68
2012 Walter MJ, Shen D, Ding L, Shao J, Koboldt DC, Chen K, Larson DE, McLellan MD, Dooling D, Abbott R, Fulton R, Magrini V, Schmidt H, Kalicki-Veizer J, O'Laughlin M, ... ... Mardis ER, et al. Clonal architecture of secondary acute myeloid leukemia. The New England Journal of Medicine. 366: 1090-8. PMID 22417201 DOI: 10.1056/NEJMoa1106968  0.68
2012 Cheung NK, Zhang J, Lu C, Parker M, Bahrami A, Tickoo SK, Heguy A, Pappo AS, Federico S, Dalton J, Cheung IY, Ding L, Fulton R, Wang J, Chen X, ... ... Mardis ER, et al. Association of age at diagnosis and genetic mutations in patients with neuroblastoma. Jama. 307: 1062-71. PMID 22416102 DOI: 10.1001/jama.2012.228  0.68
2012 Matsushita H, Vesely MD, Koboldt DC, Rickert CG, Uppaluri R, Magrini VJ, Arthur CD, White JM, Chen YS, Shea LK, Hundal J, Wendl MC, Demeter R, Wylie T, Allison JP, ... ... Mardis ER, et al. Cancer exome analysis reveals a T-cell-dependent mechanism of cancer immunoediting. Nature. 482: 400-4. PMID 22318521 DOI: 10.1038/nature10755  0.68
2012 Koboldt DC, Zhang Q, Larson DE, Shen D, McLellan MD, Lin L, Miller CA, Mardis ER, Ding L, Wilson RK. VarScan 2: somatic mutation and copy number alteration discovery in cancer by exome sequencing. Genome Research. 22: 568-76. PMID 22300766 DOI: 10.1101/gr.129684.111  0.68
2012 Wu G, Broniscer A, McEachron TA, Lu C, Paugh BS, Becksfort J, Qu C, Ding L, Huether R, Parker M, Zhang J, Gajjar A, Dyer MA, Mullighan CG, Gilbertson RJ, ... Mardis ER, et al. Somatic histone H3 alterations in pediatric diffuse intrinsic pontine gliomas and non-brainstem glioblastomas. Nature Genetics. 44: 251-3. PMID 22286216 DOI: 10.1038/ng.1102  0.68
2012 Zhang J, Ding L, Holmfeldt L, Wu G, Heatley SL, Payne-Turner D, Easton J, Chen X, Wang J, Rusch M, Lu C, Chen SC, Wei L, Collins-Underwood JR, Ma J, ... ... Mardis ER, et al. The genetic basis of early T-cell precursor acute lymphoblastic leukaemia. Nature. 481: 157-63. PMID 22237106 DOI: 10.1038/nature10725  0.68
2012 Ding L, Ley TJ, Larson DE, Miller CA, Koboldt DC, Welch JS, Ritchey JK, Young MA, Lamprecht T, McLellan MD, McMichael JF, Wallis JW, Lu C, Shen D, Harris CC, ... ... Mardis ER, et al. Clonal evolution in relapsed acute myeloid leukaemia revealed by whole-genome sequencing. Nature. 481: 506-10. PMID 22237025 DOI: 10.1038/nature10738  0.68
2012 Zhang J, Benavente CA, McEvoy J, Flores-Otero J, Ding L, Chen X, Ulyanov A, Wu G, Wilson M, Wang J, Brennan R, Rusch M, Manning AL, Ma J, Easton J, ... ... Mardis ER, et al. A novel retinoblastoma therapy from genomic and epigenetic analyses. Nature. 481: 329-34. PMID 22237022 DOI: 10.1038/nature10733  0.68
2012 Swart EC, Nowacki M, Shum J, Stiles H, Higgins BP, Doak TG, Schotanus K, Magrini VJ, Minx P, Mardis ER, Landweber LF. The Oxytricha trifallax mitochondrial genome. Genome Biology and Evolution. 4: 136-54. PMID 22179582 DOI: 10.1093/gbe/evr136  0.68
2012 Graubert TA, Shen D, Ding L, Okeyo-Owuor T, Lunn CL, Shao J, Krysiak K, Harris CC, Koboldt DC, Larson DE, McLellan MD, Dooling DJ, Abbott RM, Fulton RS, Schmidt H, ... ... Mardis ER, et al. Recurrent mutations in the U2AF1 splicing factor in myelodysplastic syndromes. Nature Genetics. 44: 53-7. PMID 22158538 DOI: 10.1038/ng.1031  0.68
2012 Larson DE, Harris CC, Chen K, Koboldt DC, Abbott TE, Dooling DJ, Ley TJ, Mardis ER, Wilson RK, Ding L. SomaticSniper: identification of somatic point mutations in whole genome sequencing data. Bioinformatics (Oxford, England). 28: 311-7. PMID 22155872 DOI: 10.1093/bioinformatics/btr665  0.68
2012 Koboldt DC, Fulton RS, McLellan MD, Schmidt H, Kalicki-Veizer J, McMichael JF, Fulton LL, Dooling DJ, Ding L, Mardis ER, Wilson RK, Ally A, Balasundaram M, Butterfield YSN, Carlsen R, et al. Comprehensive molecular portraits of human breast tumours Nature. 490: 61-70. DOI: 10.1038/nature11412  0.68
2011 Graubert TA, Mardis ER. Genomics of acute myeloid leukemia. Cancer Journal (Sudbury, Mass.). 17: 487-91. PMID 22157292 DOI: 10.1097/PPO.0b013e31823c5652  0.68
2011 Lindblad-Toh K, Garber M, Zuk O, Lin MF, Parker BJ, Washietl S, Kheradpour P, Ernst J, Jordan G, Mauceli E, Ward LD, Lowe CB, Holloway AK, Clamp M, Gnerre S, ... ... Mardis ER, et al. A high-resolution map of human evolutionary constraint using 29 mammals. Nature. 478: 476-82. PMID 21993624 DOI: 10.1038/nature10530  0.68
2011 Marth GT, Yu F, Indap AR, Garimella K, Gravel S, Leong WF, Tyler-Smith C, Bainbridge M, Blackwell T, Zheng-Bradley X, Chen Y, Challis D, Clarke L, Ball EV, Cibulskis K, ... ... Mardis E, et al. The functional spectrum of low-frequency coding variation. Genome Biology. 12: R84. PMID 21917140 DOI: 10.1186/gb-2011-12-9-r84  0.68
2011 Church DM, Schneider VA, Graves T, Auger K, Cunningham F, Bouk N, Chen HC, Agarwala R, McLaren WM, Ritchie GR, Albracht D, Kremitzki M, Rock S, Kotkiewicz H, Kremitzki C, ... ... Mardis ER, et al. Modernizing reference genome assemblies. Plos Biology. 9: e1001091. PMID 21750661 DOI: 10.1371/journal.pbio.1001091  0.68
2011 Jung S, Swart EC, Minx PJ, Magrini V, Mardis ER, Landweber LF, Eddy SR. Exploiting Oxytricha trifallax nanochromosomes to screen for non-coding RNA genes. Nucleic Acids Research. 39: 7529-47. PMID 21715380 DOI: 10.1093/nar/gkr501  0.68
2011 Wang J, Mullighan CG, Easton J, Roberts S, Heatley SL, Ma J, Rusch MC, Chen K, Harris CC, Ding L, Holmfeldt L, Payne-Turner D, Fan X, Wei L, Zhao D, ... ... Mardis ER, et al. CREST maps somatic structural variation in cancer genomes with base-pair resolution. Nature Methods. 8: 652-4. PMID 21666668 DOI: 10.1038/nmeth.1628  0.68
2011 Forgetta V, Oughton MT, Marquis P, Brukner I, Blanchette R, Haub K, Magrini V, Mardis ER, Gerding DN, Loo VG, Miller MA, Mulvey MR, Rupnik M, Dascal A, Dewar K. Fourteen-genome comparison identifies DNA markers for severe-disease-associated strains of Clostridium difficile. Journal of Clinical Microbiology. 49: 2230-8. PMID 21508155 DOI: 10.1128/JCM.00391-11  0.68
2011 Welch JS, Westervelt P, Ding L, Larson DE, Klco JM, Kulkarni S, Wallis J, Chen K, Payton JE, Fulton RS, Veizer J, Schmidt H, Vickery TL, Heath S, Watson MA, ... ... Mardis ER, et al. Use of whole-genome sequencing to diagnose a cryptic fusion oncogene. Jama. 305: 1577-84. PMID 21505136 DOI: 10.1001/jama.2011.497  0.68
2011 Link DC, Schuettpelz LG, Shen D, Wang J, Walter MJ, Kulkarni S, Payton JE, Ivanovich J, Goodfellow PJ, Le Beau M, Koboldt DC, Dooling DJ, Fulton RS, Bender RH, Fulton LL, ... ... Mardis ER, et al. Identification of a novel TP53 cancer susceptibility mutation through whole-genome sequencing of a patient with therapy-related AML. Jama. 305: 1568-76. PMID 21505135 DOI: 10.1001/jama.2011.473  0.68
2011 Wendl MC, Wallis JW, Lin L, Kandoth C, Mardis ER, Wilson RK, Ding L. PathScan: a tool for discerning mutational significance in groups of putative cancer genes. Bioinformatics (Oxford, England). 27: 1595-602. PMID 21498403 DOI: 10.1093/bioinformatics/btr193  0.68
2011 Murphy JT, Bruinsma JJ, Schneider DL, Collier S, Guthrie J, Chinwalla A, Robertson JD, Mardis ER, Kornfeld K. Histidine protects against zinc and nickel toxicity in Caenorhabditis elegans. Plos Genetics. 7: e1002013. PMID 21455490 DOI: 10.1371/journal.pgen.1002013  0.68
2011 Ye L, Hillier LW, Minx P, Thane N, Locke DP, Martin JC, Chen L, Mitreva M, Miller JR, Haub KV, Dooling DJ, Mardis ER, Wilson RK, Weinstock GM, Warren WC. A vertebrate case study of the quality of assemblies derived from next-generation sequences. Genome Biology. 12: R31. PMID 21453517 DOI: 10.1186/gb-2011-12-3-r31  0.68
2011 Wartman LD, Larson DE, Xiang Z, Ding L, Chen K, Lin L, Cahan P, Klco JM, Welch JS, Li C, Payton JE, Uy GL, Varghese N, Ries RE, Hoock M, ... ... Mardis ER, et al. Sequencing a mouse acute promyelocytic leukemia genome reveals genetic events relevant for disease progression. The Journal of Clinical Investigation. 121: 1445-55. PMID 21436584 DOI: 10.1172/JCI45284  0.68
2011 Walter MJ, Ding L, Shen D, Shao J, Grillot M, McLellan M, Fulton R, Schmidt H, Kalicki-Veizer J, O'Laughlin M, Kandoth C, Baty J, Westervelt P, Dipersio JF, Mardis ER, et al. Recurrent DNMT3A mutations in patients with myelodysplastic syndromes Leukemia. 25: 1153-1158. PMID 21415852 DOI: 10.1038/leu.2011.44  0.68
2011 Mitreva M, Jasmer DP, Zarlenga DS, Wang Z, Abubucker S, Martin J, Taylor CM, Yin Y, Fulton L, Minx P, Yang SP, Warren WC, Fulton RS, Bhonagiri V, Zhang X, ... ... Mardis ER, et al. The draft genome of the parasitic nematode Trichinella spiralis. Nature Genetics. 43: 228-35. PMID 21336279 DOI: 10.1038/ng.769  0.68
2011 Muthappan V, Lee AY, Lamprecht TL, Akileswaran L, Dintzis SM, Lee C, Magrini V, Mardis ER, Shendure J, Van Gelder RN. Biome representational in silico karyotyping. Genome Research. 21: 626-33. PMID 21324882 DOI: 10.1101/gr.115758.110  0.68
2011 Mardis ER. A decade's perspective on DNA sequencing technology Nature. 470: 198-203. PMID 21307932 DOI: 10.1038/nature09796  0.68
2011 Li L, Goedegebuure P, Mardis ER, Ellis MJC, Zhang X, Herndon JM, Fleming TP, Carreno BM, Hansen TH, Gillanders WE. Cancer genome sequencing and its implications for personalized cancer vaccines Cancers. 3: 4191-4211. DOI: 10.3390/cancers3044191  0.68
2011 Mardis ER. Future of DNA sequencing technology: Thriving sector expected to remain on its upward trajectory Genetic Engineering and Biotechnology News. 31.  0.68
2010 Ley TJ, Ding L, Walter MJ, McLellan MD, Lamprecht T, Larson DE, Kandoth C, Payton JE, Baty J, Welch J, Harris CC, Lichti CF, Townsend RR, Fulton RS, Dooling DJ, ... ... Mardis ER, et al. DNMT3A mutations in acute myeloid leukemia. The New England Journal of Medicine. 363: 2424-33. PMID 21067377 DOI: 10.1056/NEJMoa1005143  0.68
2010 Abecasis GR, Altshuler D, Auton A, Brooks LD, Durbin RM, Gibbs RA, Hurles ME, McVean GA. A map of human genome variation from population-scale sequencing. Nature. 467: 1061-73. PMID 20981092 DOI: 10.1038/nature09534  0.68
2010 Fehniger TA, Wylie T, Germino E, Leong JW, Magrini VJ, Koul S, Keppel CR, Schneider SE, Koboldt DC, Sullivan RP, Heinz ME, Crosby SD, Nagarajan R, Ramsingh G, Link DC, ... ... Mardis ER, et al. Next-generation sequencing identifies the natural killer cell microRNA transcriptome. Genome Research. 20: 1590-604. PMID 20935160 DOI: 10.1101/gr.107995.110  0.68
2010 Whittington CM, Papenfuss AT, Locke DP, Mardis ER, Wilson RK, Abubucker S, Mitreva M, Wong ES, Hsu AL, Kuchel PW, Belov K, Warren WC. Novel venom gene discovery in the platypus. Genome Biology. 11: R95. PMID 20920228 DOI: 10.1186/gb-2010-11-9-r95  0.68
2010 Ramsingh G, Koboldt DC, Trissal M, Chiappinelli KB, Wylie T, Koul S, Chang LW, Nagarajan R, Fehniger TA, Goodfellow P, Magrini V, Wilson RK, Ding L, Ley TJ, Mardis ER, et al. Complete characterization of the microRNAome in a patient with acute myeloid leukemia. Blood. 116: 5316-26. PMID 20876853 DOI: 10.1182/blood-2010-05-285395  0.68
2010 Ding L, Wendl MC, Koboldt DC, Mardis ER. Analysis of next-generation genomic data in cancer: Accomplishments and challenges Human Molecular Genetics. 19: R188-R196. PMID 20843826 DOI: 10.1093/hmg/ddq391  0.68
2010 Nielsen TO, Parker JS, Leung S, Voduc D, Ebbert M, Vickery T, Davies SR, Snider J, Stijleman IJ, Reed J, Cheang MC, Mardis ER, Perou CM, Bernard PS, Ellis MJ. A comparison of PAM50 intrinsic subtyping with immunohistochemistry and clinical prognostic factors in tamoxifen-treated estrogen receptor-positive breast cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 16: 5222-32. PMID 20837693 DOI: 10.1158/1078-0432.CCR-10-1282  0.68
2010 Bellott DW, Skaletsky H, Pyntikova T, Mardis ER, Graves T, Kremitzki C, Brown LG, Rozen S, Warren WC, Wilson RK, Page DC. Convergent evolution of chicken Z and human X chromosomes by expansion and gene acquisition. Nature. 466: 612-6. PMID 20622855 DOI: 10.1038/nature09172  0.68
2010 Koboldt DC, Ding L, Mardis ER, Wilson RK. Challenges of sequencing human genomes Briefings in Bioinformatics. 11: 484-498. PMID 20519329 DOI: 10.1093/bib/bbq016  0.68
2010 Reekie K, Metspalu A, Chanock SJ, Liu ET, Mardis ER, Scherer SW, Kwok PY, Brookes AJ. HGV2009 meeting: bigger and better studies provide more answers and more questions. Human Mutation. 31: 886-8. PMID 20506253 DOI: 10.1002/humu.21270  0.68
2010 Leung W, Shaffer CD, Cordonnier T, Wong J, Itano MS, Slawson Tempel EE, Kellmann E, Desruisseau DM, Cain C, Carrasquillo R, Chusak TM, Falkowska K, Grim KD, Guan R, Honeybourne J, ... ... Mardis ER, et al. Evolution of a distinct genomic domain in Drosophila: comparative analysis of the dot chromosome in Drosophila melanogaster and Drosophila virilis. Genetics. 185: 1519-34. PMID 20479145 DOI: 10.1534/genetics.110.116129  0.68
2010 Mardis ER. Cancer genomics identifies determinants of tumor biology Genome Biology. 11. PMID 20441611 DOI: 10.1186/gb-2010-11-5-211  0.68
2010 Ding L, Ellis MJ, Li S, Larson DE, Chen K, Wallis JW, Harris CC, McLellan MD, Fulton RS, Fulton LL, Abbott RM, Hoog J, Dooling DJ, Koboldt DC, Schmidt H, ... ... Mardis ER, et al. Genome remodelling in a basal-like breast cancer metastasis and xenograft. Nature. 464: 999-1005. PMID 20393555 DOI: 10.1038/nature08989  0.68
2010 Warren WC, Clayton DF, Ellegren H, Arnold AP, Hillier LW, Künstner A, Searle S, White S, Vilella AJ, Fairley S, Heger A, Kong L, Ponting CP, Jarvis ED, Mello CV, ... ... Mardis ER, et al. The genome of a songbird. Nature. 464: 757-62. PMID 20360741 DOI: 10.1038/nature08819  0.68
2010 Shaffer CD, Alvarez C, Bailey C, Barnard D, Bhalla S, Chandrasekaran C, Chandrasekaran V, Chung HM, Dorer DR, Du C, Eckdahl TT, Poet JL, Frohlich D, Goodman AL, Gosser Y, ... ... Mardis ER, et al. The genomics education partnership: successful integration of research into laboratory classes at a diverse group of undergraduate institutions. Cbe Life Sciences Education. 9: 55-69. PMID 20194808 DOI: 10.1187/09-11-0087  0.68
2010 Schuster SC, Miller W, Ratan A, Tomsho LP, Giardine B, Kasson LR, Harris RS, Petersen DC, Zhao F, Qi J, Alkan C, Kidd JM, Sun Y, Drautz DI, Bouffard P, ... ... Mardis ER, et al. Complete Khoisan and Bantu genomes from southern Africa. Nature. 463: 943-7. PMID 20164927 DOI: 10.1038/nature08795  0.68
2010 Hughes JF, Skaletsky H, Pyntikova T, Graves TA, van Daalen SK, Minx PJ, Fulton RS, McGrath SD, Locke DP, Friedman C, Trask BJ, Mardis ER, Warren WC, Repping S, Rozen S, et al. Chimpanzee and human Y chromosomes are remarkably divergent in structure and gene content. Nature. 463: 536-9. PMID 20072128 DOI: 10.1038/nature08700  0.68
2010 Zhang Q, Ding L, Larson DE, Koboldt DC, McLellan MD, Chen K, Shi X, Kraja A, Mardis ER, Wilson RK, Borecki IB, Province MA. CMDS: a population-based method for identifying recurrent DNA copy number aberrations in cancer from high-resolution data. Bioinformatics (Oxford, England). 26: 464-9. PMID 20031968 DOI: 10.1093/bioinformatics/btp708  0.68
2010 Mardis ER. The $1,000 genome, the $100,000 analysis? Genome Medicine. 2. DOI: 10.1186/gm205  0.68
2009 Walter MJ, Graubert TA, Dipersio JF, Mardis ER, Wilson RK, Ley TJ. Next-generation sequencing of cancer genomes: back to the future. Personalized Medicine. 6: 653. PMID 20161678 DOI: 10.2217/pme.09.52  0.68
2009 Manolio TA, Collins FS, Cox NJ, Goldstein DB, Hindorff LA, Hunter DJ, McCarthy MI, Ramos EM, Cardon LR, Chakravarti A, Cho JH, Guttmacher AE, Kong A, Kruglyak L, Mardis E, et al. Finding the missing heritability of complex diseases. Nature. 461: 747-53. PMID 19812666 DOI: 10.1038/nature08494  0.68
2009 Mardis ER, Wilson RK. Cancer genome sequencing: A review Human Molecular Genetics. 18: R163-R168. PMID 19808792 DOI: 10.1093/hmg/ddp396  0.68
2009 Diguistini S, Liao NY, Platt D, Robertson G, Seidel M, Chan SK, Docking TR, Birol I, Holt RA, Hirst M, Mardis E, Marra MA, Hamelin RC, Bohlmann J, Breuil C, et al. De novo genome sequence assembly of a filamentous fungus using Sanger, 454 and Illumina sequence data. Genome Biology. 10: R94. PMID 19747388 DOI: 10.1186/gb-2009-10-9-r94  0.68
2009 Chen K, Wallis JW, McLellan MD, Larson DE, Kalicki JM, Pohl CS, McGrath SD, Wendl MC, Zhang Q, Locke DP, Shi X, Fulton RS, Ley TJ, Wilson RK, Ding L, ... Mardis ER, et al. BreakDancer: an algorithm for high-resolution mapping of genomic structural variation. Nature Methods. 6: 677-81. PMID 19668202 DOI: 10.1038/nmeth.1363  0.68
2009 Mardis ER, Ding L, Dooling DJ, Larson DE, McLellan MD, Chen K, Koboldt DC, Fulton RS, Delehaunty KD, McGrath SD, Fulton LA, Locke DP, Magrini VJ, Abbott RM, Vickery TL, et al. Recurring mutations found by sequencing an acute myeloid leukemia genome. The New England Journal of Medicine. 361: 1058-66. PMID 19657110 DOI: 10.1056/NEJMoa0903840  0.68
2009 Walter MJ, Payton JE, Ries RE, Shannon WD, Deshmukh H, Zhao Y, Baty J, Heath S, Westervelt P, Watson MA, Tomasson MH, Nagarajan R, O'Gara BP, Bloomfield CD, Mrózek K, ... ... Mardis ER, et al. Acquired copy number alterations in adult acute myeloid leukemia genomes. Proceedings of the National Academy of Sciences of the United States of America. 106: 12950-5. PMID 19651600 DOI: 10.1073/pnas.0903091106  0.68
2009 Romanov MN, Tuttle EM, Houck ML, Modi WS, Chemnick LG, Korody ML, Mork EM, Otten CA, Renner T, Jones KC, Dandekar S, Papp JC, Da Y, Green ED, ... ... Mardis ER, et al. The value of avian genomics to the conservation of wildlife. Bmc Genomics. 10: S10. PMID 19607652 DOI: 10.1186/1471-2164-10-S2-S10  0.68
2009 Orscheln RC, Hunstad DA, Fritz SA, Loughman JA, Mitchell K, Storch EK, Gaudreault M, Sellenriek PL, Armstrong JR, Mardis ER, Storch GA. contribution of genetically restricted, methicillin-susceptible strains to the ongoing epidemic of community-acquired Staphylococcus aureus infections. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 49: 536-42. PMID 19589082 DOI: 10.1086/600881  0.68
2009 Koboldt DC, Chen K, Wylie T, Larson DE, McLellan MD, Mardis ER, Weinstock GM, Wilson RK, Ding L. VarScan: variant detection in massively parallel sequencing of individual and pooled samples. Bioinformatics (Oxford, England). 25: 2283-5. PMID 19542151 DOI: 10.1093/bioinformatics/btp373  0.68
2009 Leopold SR, Magrini V, Holt NJ, Shaikh N, Mardis ER, Cagno J, Ogura Y, Iguchi A, Hayashi T, Mellmann A, Karch H, Besser TE, Sawyer SA, Whittam TS, Tarr PI. A precise reconstruction of the emergence and constrained radiations of Escherichia coli O157 portrayed by backbone concatenomic analysis. Proceedings of the National Academy of Sciences of the United States of America. 106: 8713-8. PMID 19439656 DOI: 10.1073/pnas.0812949106  0.68
2009 Mitreva M, Mardis ER. Large-scale sequencing and analytical processing of ESTs Methods in Molecular Biology. 533: 153-187. PMID 19277558 DOI: 10.1007/978-1-60327-136-3_8  0.68
2009 Marques-Bonet T, Kidd JM, Ventura M, Graves TA, Cheng Z, Hillier LW, Jiang Z, Baker C, Malfavon-Borja R, Fulton LA, Alkan C, Aksay G, Girirajan S, Siswara P, Chen L, ... ... Mardis ER, et al. A burst of segmental duplications in the genome of the African great ape ancestor. Nature. 457: 877-81. PMID 19212409 DOI: 10.1038/nature07744  0.68
2009 Parker JS, Mullins M, Cheang MC, Leung S, Voduc D, Vickery T, Davies S, Fauron C, He X, Hu Z, Quackenbush JF, Stijleman IJ, Palazzo J, Marron JS, Nobel AB, ... Mardis E, et al. Supervised risk predictor of breast cancer based on intrinsic subtypes. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 27: 1160-7. PMID 19204204 DOI: 10.1200/JCO.2008.18.1370  0.68
2009 Girirajan S, Chen L, Graves T, Marques-Bonet T, Ventura M, Fronick C, Fulton L, Rocchi M, Fulton RS, Wilson RK, Mardis ER, Eichler EE. Sequencing human-gibbon breakpoints of synteny reveals mosaic new insertions at rearrangement sites. Genome Research. 19: 178-90. PMID 19029537 DOI: 10.1101/gr.086041.108  0.68
2009 Mardis ER, Lunshof JE. A focus on personal genomics Personalized Medicine. 6: 603-606. DOI: 10.2217/pme.09.63  0.68
2009 Mardis ER. New strategies and emerging technologies for massively parallel sequencing: Applications in medical research Genome Medicine. 1. DOI: 10.1186/gm40  0.68
2009 Marques-Bonet T, Kidd JM, Ventura M, Graves TA, Cheng Z, Hillier LW, Jiang Z, Baker C, Malfavon-Borja R, Fulton LA, Nazareth LV, Muzny DM, Alkan C, Aksay G, Girirajan S, ... ... Mardis ER, et al. A burst of segmental duplications in the genome of the African great ape ancestor Nature. 458: 238. DOI: 10.1038/nature07881  0.68
2008 Sharp TV, Al-Attar A, Foxler DE, Ding L, de A Vallim TQ, Zhang Y, Nijmeh HS, Webb TM, Nicholson AG, Zhang Q, Kraja A, Spendlove I, Osborne J, Mardis E, Longmore GD. The chromosome 3p21.3-encoded gene, LIMD1, is a critical tumor suppressor involved in human lung cancer development. Proceedings of the National Academy of Sciences of the United States of America. 105: 19932-7. PMID 19060205 DOI: 10.1073/pnas.0805003105  0.68
2008 Wang X, Sun Q, McGrath SD, Mardis ER, Soloway PD, Clark AG. Transcriptome-wide identification of novel imprinted genes in neonatal mouse brain Plos One. 3. PMID 19052635 DOI: 10.1371/journal.pone.0003839  0.68
2008 Ley TJ, Mardis ER, Ding L, Fulton B, McLellan MD, Chen K, Dooling D, Dunford-Shore BH, McGrath S, Hickenbotham M, Cook L, Abbott R, Larson DE, Koboldt DC, Pohl C, et al. DNA sequencing of a cytogenetically normal acute myeloid leukaemia genome. Nature. 456: 66-72. PMID 18987736 DOI: 10.1038/nature07485  0.68
2008 Lopatto D, Alvarez C, Barnard D, Chandrasekaran C, Chung HM, Du C, Eckdahl T, Goodman AL, Hauser C, Jones CJ, Kopp OR, Kuleck GA, McNeil G, Morris R, Myka JL, ... ... Mardis E, et al. Undergraduate research. Genomics Education Partnership. Science (New York, N.Y.). 322: 684-5. PMID 18974335 DOI: 10.1126/science.1165351  0.68
2008 Ding L, Getz G, Wheeler DA, Mardis ER, McLellan MD, Cibulskis K, Sougnez C, Greulich H, Muzny DM, Morgan MB, Fulton L, Fulton RS, Zhang Q, Wendl MC, Lawrence MS, et al. Somatic mutations affect key pathways in lung adenocarcinoma. Nature. 455: 1069-75. PMID 18948947 DOI: 10.1038/nature07423  0.68
2008 McLendon R, Friedman A, Bigner D, Van Meir EG, Brat DJ, Mastrogianakis GM, Olson JJ, Mikkelsen T, Lehman N, Aldape K, Yung WKA, Bogler O, Weinstein JN, VandenBerg S, Berger M, ... ... Mardis ER, et al. Comprehensive genomic characterization defines human glioblastoma genes and core pathways Nature. 455: 1061-1068. PMID 18772890 DOI: 10.1038/nature07385  0.68
2008 Alekseyenko AA, Peng S, Larschan E, Gorchakov AA, Lee OK, Kharchenko P, McGrath SD, Wang CI, Mardis ER, Park PJ, Kuroda MI. A sequence motif within chromatin entry sites directs MSL establishment on the Drosophila X chromosome. Cell. 134: 599-609. PMID 18724933 DOI: 10.1016/j.cell.2008.06.033  0.68
2008 Mardis ER. Next-generation DNA sequencing methods Annual Review of Genomics and Human Genetics. 9: 387-402. PMID 18576944 DOI: 10.1146/annurev.genom.9.081307.164359  0.68
2008 Dolgosheina EV, Morin RD, Aksay G, Sahinalp SC, Magrini V, Mardis ER, Mattsson J, Unrau PJ. Conifers have a unique small RNA silencing signature Rna. 14: 1508-1515. PMID 18566193 DOI: 10.1261/rna.1052008  0.68
2001 Lander ES, Linton LM, Birren B, Nusbaum C, Zody MC, Baldwin J, Devon K, Dewar K, Doyle M, FitzHugh W, Funke R, Gage D, Harris K, Heaford A, Howland J, ... ... Mardis ER, et al. Initial sequencing and analysis of the human genome. Nature. 409: 860-921. PMID 11237011 DOI: 10.1038/35057062  0.68
1992 Labidi A, Mardis E, Roe BA, Wallace RJ. Cloning and DNA sequence of the Mycobacterium fortuitum var fortuitum plasmid pAL5000. Plasmid. 27: 130-40. PMID 1615063  0.68
1990 Stover CK, Marana DP, Carter JM, Roe BA, Mardis E, Oaks EV. The 56-kilodalton major protein antigen of Rickettsia tsutsugamushi: molecular cloning and sequence analysis of the sta56 gene and precise identification of a strain-specific epitope. Infection and Immunity. 58: 2076-84. PMID 1694818  0.68
1989 Mardis ER, Roe BA. Automated methods for single-stranded DNA isolation and dideoxynucleotide DNA sequencing reactions on a robotic workstation. Biotechniques. 7: 840-50. PMID 2698662  0.68
1988 Roe BA, Johnston-Dow L, Mardis E. Use of a chemically modified T7 DNA polymerase for manual and automated sequencing of supercoiled DNA. Biotechniques. 6: 520. PMID 3273184  0.68
Show low-probability matches.