| Year |
Citation |
Score |
| 2024 |
Goel VY, Aboreden NG, Jusuf JM, Zhang H, Mori LP, Mirny LA, Blobel GA, Banigan EJ, Hansen AS. Dynamics of microcompartment formation at the mitosis-to-G1 transition. Biorxiv : the Preprint Server For Biology. PMID 39345388 DOI: 10.1101/2024.09.16.611917 |
0.32 |
|
| 2024 |
Aboreden NG, Lam JC, Goel VY, Wang S, Wang X, Midla SC, Quijano A, Keller CA, Giardine BM, Hardison RC, Zhang H, Hansen AS, Blobel GA. LDB1 establishes multi-enhancer networks to regulate gene expression. Biorxiv : the Preprint Server For Biology. PMID 39229045 DOI: 10.1101/2024.08.23.609430 |
0.419 |
|
| 2024 |
Lam JC, Aboreden NG, Midla SC, Wang S, Huang A, Keller CA, Giardine B, Henderson KA, Hardison RC, Zhang H, Blobel GA. YY1-controlled regulatory connectivity and transcription are influenced by the cell cycle. Nature Genetics. PMID 39210046 DOI: 10.1038/s41588-024-01871-y |
0.459 |
|
| 2024 |
Xiang G, He X, Giardine BM, Isaac KJ, Taylor DJ, McCoy RC, Jansen C, Keller CA, Wixom AQ, Cockburn A, Miller A, Qi Q, He Y, Li Y, Lichtenberg J, ... ... Blobel GA, et al. Interspecies regulatory landscapes and elements revealed by novel joint systematic integration of human and mouse blood cell epigenomes. Genome Research. PMID 38951027 DOI: 10.1101/gr.277950.123 |
0.391 |
|
| 2024 |
Huang P, Peslak SA, Shehu V, Keller CA, Giardine BM, Shi J, Hardison RC, Blobel GA, Khandros E. Let-7 miRNAs repress HIC2 to regulate BCL11A transcription and hemoglobin switching. Blood. PMID 38364109 DOI: 10.1182/blood.2023023399 |
0.308 |
|
| 2023 |
Sroka MW, Skopelitis D, Vermunt MW, Preall JB, El Demerdash O, de Almeida LMN, Chang K, Utama R, Gryder B, Caligiuri G, Ren D, Nalbant B, Milazzo JP, Tuveson DA, Dobin A, ... ... Blobel GA, et al. Myo-differentiation reporter screen reveals NF-Y as an activator of PAX3-FOXO1 in rhabdomyosarcoma. Proceedings of the National Academy of Sciences of the United States of America. 120: e2303859120. PMID 37639593 DOI: 10.1073/pnas.2303859120 |
0.671 |
|
| 2023 |
Huang P, Peslak SA, Ren R, Khandros E, Qin K, Keller CA, Giardine B, Bell HW, Lan X, Sharma M, Horton JR, Abdulmalik O, Chou ST, Shi J, Crossley M, ... ... Blobel GA, et al. Author Correction: HIC2 controls developmental hemoglobin switching by repressing BCL11A transcription. Nature Genetics. PMID 37524792 DOI: 10.1038/s41588-023-01488-7 |
0.311 |
|
| 2023 |
Zhang H, Blobel GA. Genome folding dynamics during the M-to-G1-phase transition. Current Opinion in Genetics & Development. 80: 102036. PMID 37099832 DOI: 10.1016/j.gde.2023.102036 |
0.303 |
|
| 2023 |
Xiang G, He X, Giardine BM, Weaver KJ, Taylor DJ, McCoy RC, Jansen C, Keller CA, Wixom AQ, Cockburn A, Miller A, Qi Q, He Y, Li Y, Lichtenberg J, ... ... Blobel GA, et al. Cross-species regulatory landscapes and elements revealed by novel joint systematic integration of human and mouse blood cell epigenomes. Biorxiv : the Preprint Server For Biology. PMID 37066352 DOI: 10.1101/2023.04.02.535219 |
0.351 |
|
| 2023 |
Qin K, Lan X, Huang P, Saari MS, Khandros E, Keller CA, Giardine BM, Abdulmalik O, Shi J, Hardison RC, Blobel GA. Molecular basis of polycomb group protein-mediated fetal hemoglobin repression. Blood. PMID 36893455 DOI: 10.1182/blood.2022019578 |
0.382 |
|
| 2023 |
Vermunt MW, Luan J, Zhang Z, Thrasher AJ, Huang A, Saari MS, Khandros E, Beagrie RA, Zhang S, Vemulamada P, Brilleman M, Lee K, Yano JA, Giardine BM, Keller CA, ... ... Blobel GA, et al. Gene silencing dynamics are modulated by transiently active regulatory elements. Molecular Cell. 83: 715-730.e6. PMID 36868189 DOI: 10.1016/j.molcel.2023.02.006 |
0.499 |
|
| 2023 |
Peslak SA, Demirci S, Chandra V, Ryu B, Bhardwaj SK, Jiang J, Rupon JW, Throm RE, Uchida N, Leonard A, Essawi K, Bonifacino AC, Krouse AE, Linde NS, Donahue RE, ... ... Blobel GA, et al. Forced enhancer-promoter rewiring to alter gene expression in animal models. Molecular Therapy. Nucleic Acids. 31: 452-465. PMID 36852088 DOI: 10.1016/j.omtn.2023.01.016 |
0.415 |
|
| 2022 |
Luan J, Vermunt MW, Syrett CM, Coté A, Tome JM, Zhang H, Huang A, Luppino JM, Keller CA, Giardine BM, Zhang S, Dunagin MC, Zhang Z, Joyce EF, Lis JT, ... ... Blobel GA, et al. CTCF blocks antisense transcription initiation at divergent promoters. Nature Structural & Molecular Biology. 29: 1136-1144. PMID 36369346 DOI: 10.1038/s41594-022-00855-y |
0.671 |
|
| 2022 |
Feng R, Mayuranathan T, Huang P, Doerfler PA, Li Y, Yao Y, Zhang J, Palmer LE, Mayberry K, Christakopoulos GE, Xu P, Li C, Cheng Y, Blobel GA, Simon MC, et al. Activation of γ-globin expression by hypoxia-inducible factor 1α. Nature. PMID 36224385 DOI: 10.1038/s41586-022-05312-w |
0.436 |
|
| 2022 |
Huang P, Peslak SA, Ren R, Khandros E, Qin K, Keller CA, Giardine B, Bell HW, Lan X, Sharma M, Horton JR, Abdulmalik O, Chou ST, Shi J, Crossley M, ... ... Blobel GA, et al. HIC2 controls developmental hemoglobin switching by repressing BCL11A transcription. Nature Genetics. PMID 35941187 DOI: 10.1038/s41588-022-01152-6 |
0.497 |
|
| 2022 |
Wakabayashi A, Kihiu M, Sharma M, Thrasher AJ, Saari MS, Quesnel-Vallieres M, Abdulmalik O, Peslak SA, Khandros E, Keller CA, Giardine BM, Barash Y, Hardison RC, Shi J, Blobel GA. Identification and characterization of RBM12 as a novel regulator of fetal hemoglobin expression. Blood Advances. PMID 35622975 DOI: 10.1182/bloodadvances.2022007904 |
0.435 |
|
| 2022 |
Qin K, Huang P, Feng R, Keller CA, Peslak SA, Khandros E, Saari MS, Lan X, Mayuranathan T, Doerfler PA, Abdulmalik O, Giardine B, Chou ST, Shi J, Hardison RC, ... ... Blobel GA, et al. Dual function NFI factors control fetal hemoglobin silencing in adult erythroid cells. Nature Genetics. PMID 35618846 DOI: 10.1038/s41588-022-01076-1 |
0.408 |
|
| 2022 |
Topfer S, Feng R, Huang P, Ly L, Martyn G, Blobel GA, Weiss MJ, Quinlan K, Crossley M. Disrupting the adult-globin promoter alleviates promoter competition and reactivates foetal-globin gene expression. Blood. PMID 35090172 DOI: 10.1182/blood.2021014205 |
0.425 |
|
| 2021 |
Zhang H, Lam J, Zhang D, Lan Y, Vermunt MW, Keller CA, Giardine B, Hardison RC, Blobel GA. CTCF and transcription influence chromatin structure re-configuration after mitosis. Nature Communications. 12: 5157. PMID 34453048 DOI: 10.1038/s41467-021-25418-5 |
0.516 |
|
| 2021 |
Cao Z, Budinich KA, Huang H, Ren D, Lu B, Zhang Z, Chen Q, Zhou Y, Huang YH, Alikarami F, Kingsley MC, Lenard AK, Wakabayashi A, Khandros E, Bailis W, ... ... Blobel GA, et al. ZMYND8-regulated IRF8 transcription axis is an acute myeloid leukemia dependency. Molecular Cell. PMID 34358447 DOI: 10.1016/j.molcel.2021.07.018 |
0.49 |
|
| 2021 |
Keller CA, Wixom AQ, Heuston EF, Giardine B, Hsiung CC, Long MR, Miller A, Anderson SM, Cockburn A, Blobel GA, Bodine DM, Hardison RC. Effects of sheared chromatin length on ChIP-seq quality and sensitivity. G3 (Bethesda, Md.). PMID 33788948 DOI: 10.1093/g3journal/jkab101 |
0.826 |
|
| 2021 |
Luan J, Xiang G, Gómez-García PA, Tome JM, Zhang Z, Vermunt MW, Zhang H, Huang A, Keller CA, Giardine BM, Zhang Y, Lan Y, Lis JT, Lakadamyali M, Hardison RC, ... Blobel GA, et al. Distinct properties and functions of CTCF revealed by a rapidly inducible degron system. Cell Reports. 34: 108783. PMID 33626344 DOI: 10.1016/j.celrep.2021.108783 |
0.469 |
|
| 2020 |
Lan X, Ren R, Feng R, Ly LC, Lan Y, Zhang Z, Aboreden N, Qin K, Horton JR, Grevet JD, Mayuranathan T, Abdulmalik O, Keller CA, Giardine B, Hardison RC, ... ... Blobel GA, et al. ZNF410 Uniquely Activates the NuRD Component CHD4 to Silence Fetal Hemoglobin Expression. Molecular Cell. PMID 33301730 DOI: 10.1016/j.molcel.2020.11.006 |
0.442 |
|
| 2020 |
Low JKK, Silva APG, Sharifi Tabar M, Torrado M, Webb SR, Parker BL, Sana M, Smits C, Schmidberger JW, Brillault L, Jackman MJ, Williams DC, Blobel GA, Hake SB, Shepherd NE, et al. The Nucleosome Remodeling and Deacetylase Complex Has an Asymmetric, Dynamic, and Modular Architecture. Cell Reports. 33: 108450. PMID 33264611 DOI: 10.1016/j.celrep.2020.108450 |
0.302 |
|
| 2020 |
Peslak SA, Khandros E, Huang P, Lan X, Geronimo CL, Grevet JD, Abdulmalik O, Zhang Z, Giardine BM, Keller CA, Shi J, Hardison RC, Blobel GA. HRI depletion cooperates with pharmacologic inducers to elevate fetal hemoglobin and reduce sickle cell formation. Blood Advances. 4: 4560-4572. PMID 32956454 DOI: 10.1182/Bloodadvances.2020002475 |
0.376 |
|
| 2020 |
Zhang D, Huang P, Sharma M, Keller CA, Giardine B, Zhang H, Gilgenast TG, Phillips-Cremins JE, Hardison RC, Blobel GA. Alteration of genome folding via contact domain boundary insertion. Nature Genetics. PMID 32868908 DOI: 10.1038/S41588-020-0680-8 |
0.364 |
|
| 2020 |
Huang P, Peslak SA, Lan X, Khandros E, Yano JA, Sharma M, Keller CA, Giardine BM, Qin K, Abdulmalik O, Hardison R, Shi J, Blobel GA. HRI-regulated transcription factor ATF4 activates BCL11A transcription to silence fetal hemoglobin expression. Blood. PMID 32299090 DOI: 10.1182/Blood.2020005301 |
0.597 |
|
| 2020 |
Khandros E, Huang P, Peslak SA, Sharma M, Abdulmalik O, Giardine BM, Zhang Z, Keller CA, Hardison R, Blobel GA. Understanding Heterogeneity of Fetal Hemoglobin Induction through Comparative Analysis of F- and A-erythroblasts. Blood. PMID 32268371 DOI: 10.1182/Blood.2020005058 |
0.421 |
|
| 2020 |
Xiang G, Keller CA, Heuston EF, Giardine BM, An L, Wixom AQ, Miller A, Cockburn A, Sauria MEG, Weaver K, Lichtenberg J, Göttgens B, Li Q, Bodine D, Mahony S, ... ... Blobel GA, et al. An integrative view of the regulatory and transcriptional landscapes in mouse hematopoiesis. Genome Research. PMID 32132109 DOI: 10.1101/Gr.255760.119 |
0.486 |
|
| 2019 |
Chen C, Yu W, Tober J, Gao P, He B, Lee K, Trieu T, Blobel GA, Speck NA, Tan K. Spatial Genome Re-organization between Fetal and Adult Hematopoietic Stem Cells. Cell Reports. 29: 4200-4211.e7. PMID 31851943 DOI: 10.1016/J.Celrep.2019.11.065 |
0.461 |
|
| 2019 |
Werner MT, Wang H, Hamagami N, Hsu SC, Yano JA, Stonestrom AJ, Behera V, Mackay JP, Blobel GA. Comparative structure-function analysis of bromodomain and extraterminal motif (BET) proteins in a gene-complementation system. The Journal of Biological Chemistry. PMID 31792058 DOI: 10.1074/Jbc.Ra119.010679 |
0.462 |
|
| 2019 |
Zhang H, Emerson DJ, Gilgenast TG, Titus KR, Lan Y, Huang P, Zhang D, Wang H, Keller CA, Giardine B, Hardison RC, Phillips-Cremins JE, Blobel GA. Chromatin structure dynamics during the mitosis-to-G1 phase transition. Nature. PMID 31776509 DOI: 10.1038/S41586-019-1778-Y |
0.463 |
|
| 2019 |
Hardison RC, Zhang Y, Keller CA, Xiang G, Heuston EF, An L, Lichtenberg J, Giardine BM, Bodine D, Mahony S, Li Q, Yue F, Weiss MJ, Blobel GA, Taylor J, et al. Systematic integration of GATA transcription factors and epigenomes via IDEAS paints the regulatory landscape of hematopoietic cells. Iubmb Life. PMID 31769130 DOI: 10.1002/Iub.2195 |
0.591 |
|
| 2019 |
Lan X, Khandros E, Huang P, Peslak SA, Bhardwaj SK, Grevet JD, Abdulmalik O, Wang H, Keller CA, Giardine B, Baeza J, Duffner ER, El Demerdash O, Wu XS, Vakoc CR, ... ... Blobel GA, et al. The E3 ligase adaptor molecule SPOP regulates fetal hemoglobin levels in adult erythroid cells. Blood Advances. 3: 1586-1597. PMID 31126914 DOI: 10.1182/Bloodadvances.2019032318 |
0.67 |
|
| 2019 |
Behera V, Stonestrom AJ, Hamagami N, Hsiung CC, Keller CA, Giardine B, Sidoli S, Yuan ZF, Bhanu NV, Werner MT, Wang H, Garcia BA, Hardison RC, Blobel GA. Interrogating Histone Acetylation and BRD4 as Mitotic Bookmarks of Transcription. Cell Reports. 27: 400-415.e5. PMID 30970245 DOI: 10.1016/J.Celrep.2019.03.057 |
0.861 |
|
| 2019 |
Wakabayashi A, Grevet JD, Lan X, Sharma M, Shi J, Blobel GA. Interrogating RNA Binding Proteins as Novel Regulators of Fetal Hemoglobin Expression Blood. 134: 966-966. DOI: 10.1182/Blood-2019-125901 |
0.555 |
|
| 2019 |
Peslak SA, Lan X, Khandros E, Huang P, Yano JA, Grevet JD, Abdulmalik O, Keller CA, Hardison RC, Shi J, Blobel GA. Heme-Regulated Inhibitor (HRI) Depletion Cooperates with Pharmacologic Inducers to Strongly Elevate Fetal Hemoglobin and Reduce Sickle Cell Formation Blood. 134: 3557-3557. DOI: 10.1182/Blood-2019-125664 |
0.39 |
|
| 2019 |
Khandros E, Huang P, Peslak SA, Giardine B, Zhang Z, Keller CA, Hardison RC, Blobel GA. Understanding Heterogeneity of Fetal Hemoglobin Induction through Comparative Analysis of Stage-Matched F- and a-Cells Blood. 134: 981-981. DOI: 10.1182/Blood-2019-124099 |
0.46 |
|
| 2019 |
Huang P, Peslak SA, Lan X, Khandros E, Sharma M, Qin K, Keller CA, Giardine B, Shi J, Hardison RC, Blobel GA. Heme-Regulated Inhibitor (HRI) Activates Transcription Factor ATF4 to Promote BCL11A Transcription and Fetal Hemoglobin Silencing Blood. 134: 814-814. DOI: 10.1182/Blood-2019-123837 |
0.623 |
|
| 2018 |
Bartman CR, Hamagami N, Keller CA, Giardine B, Hardison RC, Blobel GA, Raj A. Transcriptional Burst Initiation and Polymerase Pause Release Are Key Control Points of Transcriptional Regulation. Molecular Cell. PMID 30554946 DOI: 10.1016/J.Molcel.2018.11.004 |
0.83 |
|
| 2018 |
Vermunt MW, Zhang D, Blobel GA. The interdependence of gene-regulatory elements and the 3D genome. The Journal of Cell Biology. PMID 30442643 DOI: 10.1083/Jcb.201809040 |
0.516 |
|
| 2018 |
Blobel GA, Crossley M. Charting a noncoding gene for γ-globin activation. Blood. 132: 1865-1867. PMID 30385490 DOI: 10.1182/Blood-2018-09-873620 |
0.393 |
|
| 2018 |
Demirci S, Bhardwaj SK, Uchida N, Haro-Mora JJ, Ryu B, Blobel GA, Tisdale JF. Robust erythroid differentiation system for rhesus hematopoietic progenitor cells allowing preclinical screening of genetic treatment strategies for the hemoglobinopathies. Cytotherapy. PMID 30249524 DOI: 10.1016/J.Jcyt.2018.07.002 |
0.363 |
|
| 2018 |
Grevet JD, Lan X, Hamagami N, Edwards CR, Sankaranarayanan L, Ji X, Bhardwaj SK, Face CJ, Posocco DF, Abdulmalik O, Keller CA, Giardine B, Sidoli S, Garcia BA, Chou ST, ... ... Blobel GA, et al. Domain-focused CRISPR screen identifies HRI as a fetal hemoglobin regulator in human erythroid cells. Science (New York, N.Y.). 361: 285-290. PMID 30026227 DOI: 10.1126/Science.Aao0932 |
0.403 |
|
| 2018 |
Wai DC, Szyszka TN, Campbell AE, Kwong C, Wilkinson-White LE, Silva APG, Low JKK, Kwan AH, Gamsjaeger R, Chalmers JN, Patrick WM, Lu B, Vakoc CR, Blobel G, Mackay JP. The BRD3 ET domain recognizes a short peptide motif through a mechanism that is conserved across chromatin remodelers and transcriptional regulators. The Journal of Biological Chemistry. PMID 29567837 DOI: 10.1074/Jbc.Ra117.000678 |
0.704 |
|
| 2018 |
Behera V, Evans P, Face CJ, Hamagami N, Sankaranarayanan L, Keller CA, Giardine B, Tan K, Hardison RC, Shi J, Blobel GA. Exploiting genetic variation to uncover rules of transcription factor binding and chromatin accessibility. Nature Communications. 9: 782. PMID 29472540 DOI: 10.1038/S41467-018-03082-6 |
0.5 |
|
| 2018 |
Lan X, Khandros E, Grevet JD, Peslak SA, Bhardwaj S, Keller CA, Giardine B, Garcia BA, Hardison RC, Shi J, Blobel GA. Domain-Focused CRISPR-Cas9 Screen Identifies the E3 Ubiquitin Ligase Substrate Adaptor Protein SPOP as a Novel Repressor of Fetal Hemoglobin Blood. 132: 414-414. DOI: 10.1182/Blood-2018-99-119518 |
0.484 |
|
| 2018 |
Peslak SA, Grevet JD, Lan X, Abdulmalik O, Shi J, Blobel GA. Heme-Regulated Inhibitor (HRI) Loss and Pharmacologic Treatments Cooperate to Strongly Elevate Fetal Hemoglobin and Reduce Sickle Cell Formation Blood. 132: 721-721. DOI: 10.1182/Blood-2018-99-117436 |
0.396 |
|
| 2017 |
Hsu SC, Blobel GA. The Role of Bromodomain and Extraterminal Motif (BET) Proteins in Chromatin Structure. Cold Spring Harbor Symposia On Quantitative Biology. PMID 29196562 DOI: 10.1101/Sqb.2017.82.033829 |
0.461 |
|
| 2017 |
Gallagher MD, Posavi M, Huang P, Unger TL, Berlyand Y, Gruenewald AL, Chesi A, Manduchi E, Wells AD, Grant SFA, Blobel GA, Brown CD, Chen-Plotkin AS. A Dementia-Associated Risk Variant near TMEM106B Alters Chromatin Architecture and Gene Expression. American Journal of Human Genetics. PMID 29056226 DOI: 10.1016/J.Ajhg.2017.09.004 |
0.382 |
|
| 2017 |
Huang P, Keller CA, Giardine B, Grevet JD, Davies JOJ, Hughes JR, Kurita R, Nakamura Y, Hardison RC, Blobel GA. Comparative analysis of three-dimensional chromosomal architecture identifies a novel fetal hemoglobin regulatory element. Genes & Development. PMID 28916711 DOI: 10.1101/Gad.303461.117 |
0.5 |
|
| 2017 |
Hsu SC, Gilgenast TG, Bartman CR, Edwards CR, Stonestrom AJ, Huang P, Emerson DJ, Evans P, Werner MT, Keller CA, Giardine B, Hardison RC, Raj A, Phillips-Cremins JE, Blobel GA. The BET Protein BRD2 Cooperates with CTCF to Enforce Transcriptional and Architectural Boundaries. Molecular Cell. 66: 102-116.e7. PMID 28388437 DOI: 10.1016/J.Molcel.2017.02.027 |
0.835 |
|
| 2017 |
Deng W, Blobel GA. Detecting Long-Range Enhancer-Promoter Interactions by Quantitative Chromosome Conformation Capture. Methods in Molecular Biology (Clifton, N.J.). 1468: 51-62. PMID 27662870 DOI: 10.1007/978-1-4939-4035-6_6 |
0.592 |
|
| 2017 |
Werner MT, Hsu SC, Blobel GA. BRD3 (bromodomain containing 3) Atlas of Genetics and Cytogenetics in Oncology and Haematology. DOI: 10.4267/2042/62771 |
0.374 |
|
| 2017 |
Grevet JD, Hamagami N, Lan X, Sankaranarayanan L, Bhardwaj S, Face C, Posocco D, Abdulmalik O, Keller CA, Giardine B, Sidoli S, Garcia B, Chou ST, Hardison RC, Vakoc C, ... ... Blobel GA, et al. Domain-Focused CRISPR-Cas9 Screen Identifies Hri Kinase As a Regulator of Fetal Hemoglobin in Adult Human Erythroid Cells Blood. 130: 536-536. DOI: 10.1182/Blood.V130.Suppl_1.536.536 |
0.49 |
|
| 2016 |
Hsiung CC, Blobel GA. A new bookmark of the mitotic genome in embryonic stem cells. Nature Cell Biology. 18: 1124-1125. PMID 27784905 DOI: 10.1038/Ncb3432 |
0.824 |
|
| 2016 |
Stonestrom AJ, Hsu SC, Werner MT, Blobel GA. Erythropoiesis provides a BRD's eye view of BET protein function. Drug Discovery Today. Technologies. 19: 23-28. PMID 27769353 DOI: 10.1016/J.Ddtec.2016.05.004 |
0.311 |
|
| 2016 |
Xia Q, Chesi A, Manduchi E, Johnston BT, Lu S, Leonard ME, Parlin UW, Rappaport EF, Huang P, Wells AD, Blobel GA, Johnson ME, Grant SF. The type 2 diabetes presumed causal variant within TCF7L2 resides in an element that controls the expression of ACSL5. Diabetologia. PMID 27539148 DOI: 10.1007/S00125-016-4077-2 |
0.321 |
|
| 2016 |
Traxler EA, Yao Y, Wang YD, Woodard KJ, Kurita R, Nakamura Y, Hughes JR, Hardison RC, Blobel GA, Li C, Weiss MJ. A genome-editing strategy to treat β-hemoglobinopathies that recapitulates a mutation associated with a benign genetic condition. Nature Medicine. PMID 27525524 DOI: 10.1038/Nm.4170 |
0.366 |
|
| 2016 |
Breda L, Motta I, Lourenco S, Gemmo C, Deng W, Rupon JW, Abdulmalik OY, Manwani D, Blobel GA, Rivella S. Forced chromatin looping raises fetal hemoglobin in adult sickle cells to higher levels than pharmacologic inducers. Blood. PMID 27405777 DOI: 10.1182/Blood-2016-01-691089 |
0.676 |
|
| 2016 |
Lee K, Blobel GA. Chromatin architecture underpinning transcription elongation. Nucleus (Austin, Tex.). 0. PMID 27366856 DOI: 10.1080/19491034.2016.1200770 |
0.578 |
|
| 2016 |
Hsiung CC, Bartman CR, Huang P, Ginart P, Stonestrom AJ, Keller CA, Face C, Jahn KS, Evans P, Sankaranarayanan L, Giardine B, Hardison RC, Raj A, Blobel GA. A hyperactive transcriptional state marks genome reactivation at the mitosis-G1 transition. Genes & Development. 30: 1423-39. PMID 27340175 DOI: 10.1101/Gad.280859.116 |
0.833 |
|
| 2016 |
Bartman CR, Hsu SC, Hsiung CC, Raj A, Blobel GA. Enhancer Regulation of Transcriptional Bursting Parameters Revealed by Forced Chromatin Looping. Molecular Cell. PMID 27067601 DOI: 10.1016/J.Molcel.2016.03.007 |
0.832 |
|
| 2016 |
Paralkar VR, Taborda CC, Huang P, Yao Y, Kossenkov AV, Prasad R, Luan J, Davies JO, Hughes JR, Hardison RC, Blobel GA, Weiss MJ. Unlinking an lncRNA from Its Associated cis Element. Molecular Cell. PMID 27041223 DOI: 10.1016/J.Molcel.2016.02.029 |
0.586 |
|
| 2016 |
Edwards CR, Ritchie W, Wong JJ, Schmitz U, Middleton R, An X, Mohandas N, Rasko JE, Blobel GA. A dynamic intron retention program in the mammalian megakaryocyte and erythrocyte lineages. Blood. PMID 26962124 DOI: 10.1182/Blood-2016-01-692764 |
0.45 |
|
| 2016 |
Naraparaju K, Kolla V, Zhuang T, Higashi M, Iyer R, Kolla S, Okawa ER, Blobel GA, Brodeur GM. Role of microRNAs in epigenetic silencing of the CHD5 tumor suppressor gene in neuroblastomas. Oncotarget. PMID 26895110 DOI: 10.18632/Oncotarget.7434 |
0.31 |
|
| 2016 |
Behera V, Evans P, Face CJ, Sankaranarayanan L, Blobel GA. Deep Mining of Natural Genetic Variation in Erythroid Cells Reveals New Insights about In Vivo Transcription Factor Binding and Chromatin Accessibility Blood. 128: 3879-3879. DOI: 10.1182/Blood.V128.22.3879.3879 |
0.547 |
|
| 2016 |
Hsu SC, Bartman C, Stonestrom AJ, Edwards CR, Gilgenast T, Emerson D, Huang P, Werner MT, Jahn K, Keller CA, Giardine B, Hardison RC, Raj A, Phillips-Cremins JE, Blobel GA. The BET Protein BRD2 Cooperates with CTCF to Enforce a Transcriptional Boundary in Erythroid Cells Blood. 128: 1034-1034. DOI: 10.1182/Blood.V128.22.1034.1034 |
0.846 |
|
| 2015 |
Lee K, Hsiung CC, Huang P, Raj A, Blobel GA. Corrigendum: Dynamic enhancer-gene body contacts during transcription elongation. Genes & Development. 29: 2217. PMID 26494793 |
0.822 |
|
| 2015 |
Lee K, Hsiung CC, Huang P, Raj A, Blobel GA. Dynamic enhancer-gene body contacts during transcription elongation. Genes & Development. 29: 1992-7. PMID 26443845 DOI: 10.1101/Gad.255265.114 |
0.834 |
|
| 2015 |
Bartman CR, Blobel GA. Perturbing Chromatin Structure to Understand Mechanisms of Gene Expression. Cold Spring Harbor Symposia On Quantitative Biology. PMID 26370411 DOI: 10.1101/Sqb.2015.80.027359 |
0.783 |
|
| 2015 |
Blobel G, Bodine D, Brand M, Crispino J, De Bruijn M, Nathan D, Pappayannopoulou T, Porcher C, Strouboulis J, Zon L, Higgs DR, Stamatoyannopoulos G, Engel JD. An International Effort to Cure a Global Health Problem: A report on the 19th Hemoglobin Switching Conference. Experimental Hematology. PMID 26143582 DOI: 10.1016/J.Exphem.2015.06.008 |
0.522 |
|
| 2015 |
Dogan N, Wu W, Morrissey CS, Chen KB, Stonestrom A, Long M, Keller CA, Cheng Y, Jain D, Visel A, Pennacchio LA, Weiss MJ, Blobel GA, Hardison RC. Occupancy by key transcription factors is a more accurate predictor of enhancer activity than histone modifications or chromatin accessibility. Epigenetics & Chromatin. 8: 16. PMID 25984238 DOI: 10.1186/S13072-015-0009-5 |
0.547 |
|
| 2015 |
Kolla V, Naraparaju K, Zhuang T, Higashi M, Kolla S, Blobel GA, Brodeur GM. The tumour suppressor CHD5 forms a NuRD-type chromatin remodelling complex. The Biochemical Journal. 468: 345-52. PMID 25825869 DOI: 10.1042/Bj20150030 |
0.441 |
|
| 2015 |
Stonestrom AJ, Hsu SC, Jahn KS, Huang P, Keller CA, Giardine BM, Kadauke S, Campbell AE, Evans P, Hardison RC, Blobel GA. Functions of BET proteins in erythroid gene expression. Blood. 125: 2825-34. PMID 25696920 DOI: 10.1182/Blood-2014-10-607309 |
0.813 |
|
| 2015 |
Bryant JM, Donahue G, Wang X, Meyer-Ficca M, Luense LJ, Weller AH, Bartolomei MS, Blobel GA, Meyer RG, Garcia BA, Berger SL. Characterization of BRD4 during mammalian postmeiotic sperm development. Molecular and Cellular Biology. 35: 1433-48. PMID 25691659 DOI: 10.1128/Mcb.01328-14 |
0.57 |
|
| 2015 |
Byrska-Bishop M, VanDorn D, Campbell AE, Betensky M, Arca PR, Yao Y, Gadue P, Costa FF, Nemiroff RL, Blobel GA, French DL, Hardison RC, Weiss MJ, Chou ST. Pluripotent stem cells reveal erythroid-specific activities of the GATA1 N-terminus. The Journal of Clinical Investigation. 125: 993-1005. PMID 25621499 DOI: 10.1172/Jci75714 |
0.463 |
|
| 2015 |
Hsiung CC, Morrissey CS, Udugama M, Frank CL, Keller CA, Baek S, Giardine B, Crawford GE, Sung MH, Hardison RC, Blobel GA. Genome accessibility is widely preserved and locally modulated during mitosis. Genome Research. 25: 213-25. PMID 25373146 DOI: 10.1101/Gr.180646.114 |
0.849 |
|
| 2015 |
Traxler E, Yao Y, Li C, Grevet J, Huang P, Wright S, Blobel GA, Weiss MJ. Genome Editing Recreates Hereditary Persistence of Fetal Hemoglobin in Primary Human Erythroblasts Blood. 126: 640-640. DOI: 10.1182/Blood.V126.23.640.640 |
0.389 |
|
| 2015 |
Blobel GA, Hsiung CC, Huang P, Keller C, Ginart P, Jahn K, Bartman C, Stonestrom AJ, Evans P, Giardine B, Hardison RC, Raj A. A Hyperactive Transcriptional State Marks Genome Reactivation during Mitotic Exit Blood. 126: 48-48. DOI: 10.1182/Blood.V126.23.48.48 |
0.854 |
|
| 2015 |
Paralkar VR, Taborda C, Yao Y, Prasad R, Luan J, Hardison RC, Blobel GA, Weiss MJ. A Novel Regulatory Region of the p27 Locus Is Required for Normal Erythroid p27 Expression, and Produces a Long Noncoding RNA with No Detectable Function Blood. 126: 1175-1175. DOI: 10.1182/Blood.V126.23.1175.1175 |
0.571 |
|
| 2015 |
Bledsoe KL, Stonestrom A, Kadauke S, Quick L, Young R, Blobel GA, Chou MM. Abstract 486: BET protein inhibition by JQ1 blocks EWS-FLI1 activity in Ewing sarcoma Cancer Research. 75: 486-486. DOI: 10.1158/1538-7445.Am2015-486 |
0.759 |
|
| 2014 |
Grevet JD, Blobel GA. Keeping fetal hemoglobin in the loop. Cell Cycle (Georgetown, Tex.). 13: 3153-4. PMID 25485488 DOI: 10.4161/15384101.2014.969995 |
0.548 |
|
| 2014 |
Yue F, Cheng Y, Breschi A, Vierstra J, Wu W, Ryba T, Sandstrom R, Ma Z, Davis C, Pope BD, Shen Y, Pervouchine DD, Djebali S, Thurman RE, Kaul R, ... ... Blobel GA, et al. A comparative encyclopedia of DNA elements in the mouse genome. Nature. 515: 355-64. PMID 25409824 DOI: 10.1038/Nature13992 |
0.648 |
|
| 2014 |
Yashiro-Ohtani Y, Wang H, Zang C, Arnett KL, Bailis W, Ho Y, Knoechel B, Lanauze C, Louis L, Forsyth KS, Chen S, Chung Y, Schug J, Blobel GA, Liebhaber SA, et al. Long-range enhancer activity determines Myc sensitivity to Notch inhibitors in T cell leukemia. Proceedings of the National Academy of Sciences of the United States of America. 111: E4946-53. PMID 25369933 DOI: 10.1073/Pnas.1407079111 |
0.505 |
|
| 2014 |
Pimkin M, Kossenkov AV, Mishra T, Morrissey CS, Wu W, Keller CA, Blobel GA, Lee D, Beer MA, Hardison RC, Weiss MJ. Divergent functions of hematopoietic transcription factors in lineage priming and differentiation during erythro-megakaryopoiesis. Genome Research. 24: 1932-44. PMID 25319996 DOI: 10.1101/Gr.164178.113 |
0.582 |
|
| 2014 |
Wu W, Morrissey CS, Keller CA, Mishra T, Pimkin M, Blobel GA, Weiss MJ, Hardison RC. Dynamic shifts in occupancy by TAL1 are guided by GATA factors and drive large-scale reprogramming of gene expression during hematopoiesis. Genome Research. 24: 1945-62. PMID 25319994 DOI: 10.1101/Gr.164830.113 |
0.616 |
|
| 2014 |
Clifton MK, Westman BJ, Thong SY, O'Connell MR, Webster MW, Shepherd NE, Quinlan KG, Crossley M, Blobel GA, Mackay JP. The identification and structure of an N-terminal PR domain show that FOG1 is a member of the PRDM family of proteins. Plos One. 9: e106011. PMID 25162672 DOI: 10.1371/Journal.Pone.0106011 |
0.371 |
|
| 2014 |
Deng W, Rupon JW, Krivega I, Breda L, Motta I, Jahn KS, Reik A, Gregory PD, Rivella S, Dean A, Blobel GA. Reactivation of developmentally silenced globin genes by forced chromatin looping. Cell. 158: 849-60. PMID 25126789 DOI: 10.1016/J.Cell.2014.05.050 |
0.721 |
|
| 2014 |
Alqarni SS, Murthy A, Zhang W, Przewloka MR, Silva AP, Watson AA, Lejon S, Pei XY, Smits AH, Kloet SL, Wang H, Shepherd NE, Stokes PH, Blobel GA, Vermeulen M, et al. Insight into the architecture of the NuRD complex: structure of the RbAp48-MTA1 subcomplex. The Journal of Biological Chemistry. 289: 21844-55. PMID 24920672 DOI: 10.1074/Jbc.M114.558940 |
0.494 |
|
| 2014 |
Deng W, Blobel GA. Manipulating nuclear architecture. Current Opinion in Genetics & Development. 25: 1-7. PMID 24584091 DOI: 10.1016/J.Gde.2013.10.014 |
0.647 |
|
| 2014 |
Campbell AE, Hsiung CC, Blobel GA. Comparative analysis of mitosis-specific antibodies for bulk purification of mitotic populations by fluorescence-activated cell sorting. Biotechniques. 56: 90-1, 93-4. PMID 24502799 DOI: 10.2144/000114137 |
0.791 |
|
| 2014 |
Hsiung CC, Morrissey C, Udugama M, Frank C, Keller CA, Baek S, Giardine B, Crawford GE, Sung M, Raj A, Hardison RC, Blobel GA. Epigenetics of Cellular Memory: Insights from the Chromatin Accessibility Landscape of the Mitotic Genome Blood. 124: 4342-4342. DOI: 10.1182/Blood.V124.21.4342.4342 |
0.743 |
|
| 2014 |
Breda L, Rupon JW, Motta I, Deng W, Blobel GA, Rivella S. Comparing Strategies to Reactivate Fetal Globin Expression for the Treatment of Beta-Globinopathies Blood. 124: 333-333. DOI: 10.1182/Blood.V124.21.333.333 |
0.669 |
|
| 2014 |
Bartman C, Blobel GA, Grevet J, Hsiung CC, Rupon JW, Raj A. Mechanistic Insights into Forced Chromatin Looping Mediated Activation of Fetal Globin Gene Expression Blood. 124: 331-331. DOI: 10.1182/Blood.V124.21.331.331 |
0.846 |
|
| 2014 |
Stonestrom AJ, Hsu SC, Jahn KS, Hsuing CC, Huang P, Hardison RC, Blobel GA. Dissection of BET Protein Function in a Hematopoietic Differentiation Model Blood. 124: 1574-1574. DOI: 10.1182/Blood.V124.21.1574.1574 |
0.544 |
|
| 2013 |
Zheng R, Rebolledo-Jaramillo B, Zong Y, Wang L, Russo P, Hancock W, Stanger BZ, Hardison RC, Blobel GA. Function of GATA factors in the adult mouse liver. Plos One. 8: e83723. PMID 24367609 DOI: 10.1371/Journal.Pone.0083723 |
0.617 |
|
| 2013 |
Shi J, Whyte WA, Zepeda-Mendoza CJ, Milazzo JP, Shen C, Roe JS, Minder JL, Mercan F, Wang E, Eckersley-Maslin MA, Campbell AE, Kawaoka S, Shareef S, Zhu Z, Kendall J, ... ... Blobel GA, et al. Role of SWI/SNF in acute leukemia maintenance and enhancer-mediated Myc regulation. Genes & Development. 27: 2648-62. PMID 24285714 DOI: 10.1101/Gad.232710.113 |
0.753 |
|
| 2013 |
Hardison RC, Blobel GA. Genetics. GWAS to therapy by genome edits? Science (New York, N.Y.). 342: 206-7. PMID 24115432 DOI: 10.1126/Science.1245813 |
0.396 |
|
| 2013 |
Blobel GA, Hardison RC. A cluster to remember. Cell. 154: 718-20. PMID 23953105 DOI: 10.1016/J.Cell.2013.07.041 |
0.367 |
|
| 2013 |
Campbell AE, Wilkinson-White L, Mackay JP, Matthews JM, Blobel GA. Analysis of disease-causing GATA1 mutations in murine gene complementation systems. Blood. 121: 5218-27. PMID 23704091 DOI: 10.1182/Blood-2013-03-488080 |
0.429 |
|
| 2013 |
Kadauke S, Blobel GA. Mitotic bookmarking by transcription factors. Epigenetics & Chromatin. 6: 6. PMID 23547918 DOI: 10.1186/1756-8935-6-6 |
0.818 |
|
| 2013 |
Lai F, Orom UA, Cesaroni M, Beringer M, Taatjes DJ, Blobel GA, Shiekhattar R. Activating RNAs associate with Mediator to enhance chromatin architecture and transcription. Nature. 494: 497-501. PMID 23417068 DOI: 10.1038/Nature11884 |
0.532 |
|
| 2013 |
Gamsjaeger R, Silva A, Shepherd N, Wilkinson-White L, Laue E, Blobel G, Matthews J, Mackav J. Elucidating the mechanisms underlying GATA-1 activity Epigenetics & Chromatin. 6. DOI: 10.1186/1756-8935-6-S1-P49 |
0.59 |
|
| 2013 |
Rupon JW, Deng W, Wang H, Gregory PD, Reik A, Dean A, Blobel GA. Using Forced Chromatin Looping To Overcome Developmental Silencing Of Embryonic and Fetal β-Type Globin Genes In Adult Erythroid Cells Blood. 122: 433-433. DOI: 10.1182/Blood.V122.21.433.433 |
0.698 |
|
| 2013 |
Hsiung CC, Raj A, Blobel GA. Hematopoietic Transcriptional Regulation At The Mitosis-G1 Transition Blood. 122: 2440-2440. DOI: 10.1182/Blood.V122.21.2440.2440 |
0.73 |
|
| 2013 |
Deng W, Rupon JW, Wang H, Reik A, Gregory PD, Blobel GA. Controlling long-range genomic interactions to reprogram the β-globin locus Epigenetics & Chromatin. 6. DOI: 10.1182/Blood.V120.21.280.280 |
0.717 |
|
| 2012 |
Kadauke S, Blobel GA. "Remembering" tissue-specific transcription patterns through mitosis. Cell Cycle (Georgetown, Tex.). 11: 3911-2. PMID 23032269 DOI: 10.4161/Cc.22237 |
0.849 |
|
| 2012 |
Kadauke S, Udugama MI, Pawlicki JM, Achtman JC, Jain DP, Cheng Y, Hardison RC, Blobel GA. Tissue-specific mitotic bookmarking by hematopoietic transcription factor GATA1. Cell. 150: 725-37. PMID 22901805 DOI: 10.1016/J.Cell.2012.06.038 |
0.827 |
|
| 2012 |
Stamatoyannopoulos JA, Snyder M, Hardison R, Ren B, Gingeras T, Gilbert DM, Groudine M, Bender M, Kaul R, Canfield T, Giste E, Johnson A, Zhang M, Balasundaram G, ... ... Blobel GA, et al. An encyclopedia of mouse DNA elements (Mouse ENCODE). Genome Biology. 13: 418. PMID 22889292 DOI: 10.1186/Gb-2012-13-8-418 |
0.567 |
|
| 2012 |
Deng W, Lee J, Wang H, Miller J, Reik A, Gregory PD, Dean A, Blobel GA. Controlling long-range genomic interactions at a native locus by targeted tethering of a looping factor. Cell. 149: 1233-44. PMID 22682246 DOI: 10.1016/J.Cell.2012.03.051 |
0.745 |
|
| 2012 |
Kadauke S, Campbell AE, Stonestrom AJ, Jain DP, Hardison RC, Blobel GA. GATA1 and the BET Family Protein Brd3 Form a Mitotic Bookmarking Complex Blood. 120: 282-282. DOI: 10.1182/Blood.V120.21.282.282 |
0.815 |
|
| 2012 |
Deng W, Rupon JW, Wang H, Reik A, Gregory PD, Blobel GA. Controlling Long-Range Genomic Interactions to Reprogram the β-Globin Locus Blood. 120: 280-280. DOI: 10.1182/blood.v120.21.280.280 |
0.685 |
|
| 2011 |
Wang Y, Meng R, Hayes V, Fuentes R, Yu X, Abrams CS, Heijnen HF, Blobel GA, Marks MS, Poncz M. Pleiotropic platelet defects in mice with disrupted FOG1-NuRD interaction. Blood. 118: 6183-91. PMID 21989988 DOI: 10.1182/Blood-2011-06-363580 |
0.3 |
|
| 2011 |
Blobel GA, Kalota A, Sanchez PV, Carroll M. Short hairpin RNA screen reveals bromodomain proteins as novel targets in acute myeloid leukemia. Cancer Cell. 20: 287-8. PMID 21907920 DOI: 10.1016/J.Ccr.2011.08.019 |
0.349 |
|
| 2011 |
Wu W, Cheng Y, Keller CA, Ernst J, Kumar SA, Mishra T, Morrissey C, Dorman CM, Chen KB, Drautz D, Giardine B, Shibata Y, Song L, Pimkin M, Crawford GE, ... ... Blobel GA, et al. Dynamics of the epigenetic landscape during erythroid differentiation after GATA1 restoration. Genome Research. 21: 1659-71. PMID 21795386 DOI: 10.1101/Gr.125088.111 |
0.615 |
|
| 2011 |
Gamsjaeger R, Webb SR, Lamonica JM, Billin A, Blobel GA, Mackay JP. Structural basis and specificity of acetylated transcription factor GATA1 recognition by BET family bromodomain protein Brd3. Molecular and Cellular Biology. 31: 2632-40. PMID 21555453 DOI: 10.1128/Mcb.05413-11 |
0.847 |
|
| 2011 |
Lamonica JM, Deng W, Kadauke S, Campbell AE, Gamsjaeger R, Wang H, Cheng Y, Billin AN, Hardison RC, Mackay JP, Blobel GA. Bromodomain protein Brd3 associates with acetylated GATA1 to promote its chromatin occupancy at erythroid target genes. Proceedings of the National Academy of Sciences of the United States of America. 108: E159-68. PMID 21536911 DOI: 10.1073/Pnas.1102140108 |
0.85 |
|
| 2011 |
Lejon S, Thong SY, Murthy A, AlQarni S, Murzina NV, Blobel GA, Laue ED, Mackay JP. Insights into association of the NuRD complex with FOG-1 from the crystal structure of an RbAp48·FOG-1 complex. The Journal of Biological Chemistry. 286: 1196-203. PMID 21047798 DOI: 10.1074/Jbc.M110.195842 |
0.435 |
|
| 2011 |
Kadauke S, Pawlicki JM, Udugama M, Achtman JC, Cheng Y, Hardison RC, Blobel GA. Lineage-Specific Mitotic Bookmarking by Hematopoietic Transcription Factor GATA1 Blood. 118: 547-547. DOI: 10.1182/Blood.V118.21.547.547 |
0.838 |
|
| 2011 |
Campbell AE, Blobel GA. Linking Transcription Factor Pathways to Disease-Causing GATA1 Mutations Blood. 118: 2371-2371. DOI: 10.1182/Blood.V118.21.2371.2371 |
0.477 |
|
| 2010 |
Zheng R, Blobel GA. GATA Transcription Factors and Cancer. Genes & Cancer. 1: 1178-88. PMID 21779441 DOI: 10.1177/1947601911404223 |
0.672 |
|
| 2010 |
Deng W, Blobel GA. Do chromatin loops provide epigenetic gene expression states? Current Opinion in Genetics & Development. 20: 548-54. PMID 20598523 DOI: 10.1016/J.Gde.2010.06.007 |
0.702 |
|
| 2010 |
Bersenev A, Wu C, Balcerek J, Jing J, Kundu M, Blobel GA, Chikwava KR, Tong W. Lnk constrains myeloproliferative diseases in mice. The Journal of Clinical Investigation. 120: 2058-69. PMID 20458146 DOI: 10.1172/Jci42032 |
0.345 |
|
| 2010 |
Miccio A, Blobel GA. Role of the GATA-1/FOG-1/NuRD pathway in the expression of human beta-like globin genes. Molecular and Cellular Biology. 30: 3460-70. PMID 20439494 DOI: 10.1128/Mcb.00001-10 |
0.48 |
|
| 2010 |
Ye Y, Pringle LM, Lau AW, Riquelme DN, Wang H, Jiang T, Lev D, Welman A, Blobel GA, Oliveira AM, Chou MM. TRE17/USP6 oncogene translocated in aneurysmal bone cyst induces matrix metalloproteinase production via activation of NF-kappaB. Oncogene. 29: 3619-29. PMID 20418905 DOI: 10.1038/Onc.2010.116 |
0.329 |
|
| 2010 |
Gregory GD, Miccio A, Bersenev A, Wang Y, Hong W, Zhang Z, Poncz M, Tong W, Blobel GA. FOG1 requires NuRD to promote hematopoiesis and maintain lineage fidelity within the megakaryocytic-erythroid compartment. Blood. 115: 2156-66. PMID 20065294 DOI: 10.1182/Blood-2009-10-251280 |
0.591 |
|
| 2010 |
Miccio A, Wang Y, Hong W, Gregory GD, Wang H, Yu X, Choi JK, Shelat S, Tong W, Poncz M, Blobel GA. NuRD mediates activating and repressive functions of GATA-1 and FOG-1 during blood development. The Embo Journal. 29: 442-56. PMID 19927129 DOI: 10.1038/Emboj.2009.336 |
0.607 |
|
| 2010 |
Deng W, Gregory PD, Reik A, Blobel G. Manipulating Higher Order Chromatin Structure of the β-Globin Locus by Targeted Tethering of a “looping” Factor Blood. 116: 647-647. DOI: 10.1182/Blood.V116.21.647.647 |
0.685 |
|
| 2010 |
Kadauke S, Lamonica JM, Lau A, Chou M, Blobel G. A Potential Epigenetic Bookmarking Function for the Hematopoietic Transcription Factor GATA-1. Blood. 116: 2601-2601. DOI: 10.1182/Blood.V116.21.2601.2601 |
0.87 |
|
| 2010 |
Lamonica JM, Kadauke S, Deng W, Blobel G. Acetylation-Dependent Interaction of GATA-1 with the Potential Mitotic “Bookmarking” Protein Brd3. Blood. 116: 2598-2598. DOI: 10.1182/Blood.V116.21.2598.2598 |
0.862 |
|
| 2009 |
Blobel GA, Kadauke S, Wang E, Lau AW, Zuber J, Chou MM, Vakoc CR. A reconfigured pattern of MLL occupancy within mitotic chromatin promotes rapid transcriptional reactivation following mitotic exit. Molecular Cell. 36: 970-83. PMID 20064463 DOI: 10.1016/J.Molcel.2009.12.001 |
0.863 |
|
| 2009 |
Cheng Y, Wu W, Kumar SA, Yu D, Deng W, Tripic T, King DC, Chen KB, Zhang Y, Drautz D, Giardine B, Schuster SC, Miller W, Chiaromonte F, Zhang Y, ... Blobel GA, et al. Erythroid GATA1 function revealed by genome-wide analysis of transcription factor occupancy, histone modifications, and mRNA expression. Genome Research. 19: 2172-84. PMID 19887574 DOI: 10.1101/Gr.098921.109 |
0.767 |
|
| 2009 |
Chou ST, Khandros E, Bailey LC, Nichols KE, Vakoc CR, Yao Y, Huang Z, Crispino JD, Hardison RC, Blobel GA, Weiss MJ. Graded repression of PU.1/Sfpi1 gene transcription by GATA factors regulates hematopoietic cell fate. Blood. 114: 983-94. PMID 19491391 DOI: 10.1182/Blood-2009-03-207944 |
0.799 |
|
| 2009 |
Vakoc CR, Wen YY, Gibbs RA, Johnstone CN, Rustgi AK, Blobel GA. Low frequency of MLL3 mutations in colorectal carcinoma. Cancer Genetics and Cytogenetics. 189: 140-1. PMID 19215798 DOI: 10.1016/J.Cancergencyto.2008.10.014 |
0.577 |
|
| 2009 |
Tripic T, Deng W, Cheng Y, Zhang Y, Vakoc CR, Gregory GD, Hardison RC, Blobel GA. SCL and associated proteins distinguish active from repressive GATA transcription factor complexes. Blood. 113: 2191-201. PMID 19011221 DOI: 10.1182/Blood-2008-07-169417 |
0.787 |
|
| 2009 |
Kadauke S, Blobel GA. Chromatin loops in gene regulation. Biochimica Et Biophysica Acta. 1789: 17-25. PMID 18675948 DOI: 10.1016/J.Bbagrm.2008.07.002 |
0.79 |
|
| 2009 |
Blobel GA, Weiss MJ. Nuclear factors that regulate erythropoiesis Disorders of Hemoglobin: Genetics, Pathophysiology, and Clinical Management, Second Edition. 62-85. DOI: 10.1017/CBO9780511596582.008 |
0.327 |
|
| 2008 |
Steger DJ, Lefterova MI, Ying L, Stonestrom AJ, Schupp M, Zhuo D, Vakoc AL, Kim JE, Chen J, Lazar MA, Blobel GA, Vakoc CR. DOT1L/KMT4 recruitment and H3K79 methylation are ubiquitously coupled with gene transcription in mammalian cells. Molecular and Cellular Biology. 28: 2825-39. PMID 18285465 DOI: 10.1128/Mcb.02076-07 |
0.747 |
|
| 2008 |
Jing H, Vakoc CR, Ying L, Mandat S, Wang H, Zheng X, Blobel GA. Exchange of GATA factors mediates transitions in looped chromatin organization at a developmentally regulated gene locus. Molecular Cell. 29: 232-42. PMID 18243117 DOI: 10.1016/J.Molcel.2007.11.020 |
0.773 |
|
| 2008 |
Roche AE, Bassett BJ, Samant SA, Hong W, Blobel GA, Svensson EC. The zinc finger and C-terminal domains of MTA proteins are required for FOG-2-mediated transcriptional repression via the NuRD complex. Journal of Molecular and Cellular Cardiology. 44: 352-60. PMID 18067919 DOI: 10.1016/J.Yjmcc.2007.10.023 |
0.509 |
|
| 2008 |
Chou ST, Bailey C, Yao Y, Huang Z, Nichols K, Crispino J, Hardison R, Blobel G, Vakoc C, Weiss MJ. Graded Repression of PU.1 Expression by GATA Factors Influence Hematopoietic Progenitor Cell Fate Blood. 112: 2469-2469. DOI: 10.1182/Blood.V112.11.2469.2469 |
0.729 |
|
| 2008 |
Gregory GD, Wang Y, Hong W, Miccio A, Bersenev A, Yu X, Wang H, Choi J, Shelat S, Tong W, Poncz M, Blobel G. The GATA-1 Cofactor FOG-1 Recruits NuRD to Promote Normal Erythroid and Megakaryocyte Development and Maintain Lineage Fidelity by Restricting Mast Cell Gene Expression. Blood. 112: 1373-1373. DOI: 10.1182/Blood.V112.11.1373.1373 |
0.562 |
|
| 2007 |
Gregory GD, Vakoc CR, Rozovskaia T, Zheng X, Patel S, Nakamura T, Canaani E, Blobel GA. Mammalian ASH1L is a histone methyltransferase that occupies the transcribed region of active genes. Molecular and Cellular Biology. 27: 8466-79. PMID 17923682 DOI: 10.1128/Mcb.00993-07 |
0.714 |
|
| 2007 |
Kim SI, Bultman SJ, Jing H, Blobel GA, Bresnick EH. Dissecting molecular steps in chromatin domain activation during hematopoietic differentiation. Molecular and Cellular Biology. 27: 4551-65. PMID 17438135 DOI: 10.1128/Mcb.00235-07 |
0.425 |
|
| 2007 |
Muntean AG, Pang L, Poncz M, Dowdy SF, Blobel GA, Crispino JD. Cyclin D-Cdk4 is regulated by GATA-1 and required for megakaryocyte growth and polyploidization. Blood. 109: 5199-207. PMID 17317855 DOI: 10.1182/Blood-2006-11-059378 |
0.551 |
|
| 2007 |
Hong W, Wang H, Wang Y, Choi JK, Shelat SG, Poncz M, Blobel GA. The GATA-1/FOG-1/NuRD Axis Is Essential for Normal Hematopoiesis. Blood. 110: 375-375. DOI: 10.1182/Blood.V110.11.375.375 |
0.576 |
|
| 2007 |
Chou ST, Bailey CL, Hardison RC, Blobel GA, Vakoc CR, Weiss MJ. GATA-1 Represses PU.1/Sfpi-1 Gene Transcription in Erythro-Megakaryocytic Progenitors. Blood. 110: 1226-1226. DOI: 10.1182/Blood.V110.11.1226.1226 |
0.76 |
|
| 2007 |
Muntean A, Pang L, Poncz M, Dowdy S, Blobel G, Crispino J. Cyclin D/CDK4/6 kinase activity, regulated by GATA1, is required for megakaryocyte polyploidization Blood Cells, Molecules, and Diseases. 38: 133. DOI: 10.1182/Blood.V108.11.780.780 |
0.58 |
|
| 2007 |
Blobel GA. Krüppeling megakaryopoiesis Blood. 110: 3823-3824. DOI: 10.1182/Blood-2007-09-110999 |
0.623 |
|
| 2007 |
Jing H, Vakoc C, Wang H, Mandat S, Miller J, Gregory P, Reik A, Blobel G. Regulation of higher order chromatin organization by GATA-1 Blood Cells, Molecules, and Diseases. 38: 126. DOI: 10.1016/J.Bcmd.2006.10.017 |
0.631 |
|
| 2006 |
Zeng PY, Vakoc CR, Chen ZC, Blobel GA, Berger SL. In vivo dual cross-linking for identification of indirect DNA-associated proteins by chromatin immunoprecipitation. Biotechniques. 41: 694, 696, 698. PMID 17191611 DOI: 10.2144/000112297 |
0.654 |
|
| 2006 |
Vakoc CR, Sachdeva MM, Wang H, Blobel GA. Profile of histone lysine methylation across transcribed mammalian chromatin. Molecular and Cellular Biology. 26: 9185-95. PMID 17030614 DOI: 10.1128/Mcb.01529-06 |
0.729 |
|
| 2006 |
Grass JA, Jing H, Kim SI, Martowicz ML, Pal S, Blobel GA, Bresnick EH. Distinct functions of dispersed GATA factor complexes at an endogenous gene locus. Molecular and Cellular Biology. 26: 7056-67. PMID 16980610 DOI: 10.1128/Mcb.01033-06 |
0.475 |
|
| 2006 |
Lamonica JM, Vakoc CR, Blobel GA. Acetylation of GATA-1 is required for chromatin occupancy. Blood. 108: 3736-8. PMID 16888089 DOI: 10.1182/Blood-2006-07-032847 |
0.861 |
|
| 2006 |
Pang L, Xue HH, Szalai G, Wang X, Wang Y, Watson DK, Leonard WJ, Blobel GA, Poncz M. Maturation stage-specific regulation of megakaryopoiesis by pointed-domain Ets proteins. Blood. 108: 2198-206. PMID 16757682 DOI: 10.1182/Blood-2006-04-019760 |
0.522 |
|
| 2006 |
Blobel GA. GATA-1 caught in the AKT Blood. 107: 851-852. DOI: 10.1182/Blood-2005-11-4425 |
0.306 |
|
| 2005 |
Vakoc CR, Mandat SA, Olenchock BA, Blobel GA. Histone H3 lysine 9 methylation and HP1gamma are associated with transcription elongation through mammalian chromatin. Molecular Cell. 19: 381-91. PMID 16061184 DOI: 10.1016/J.Molcel.2005.06.011 |
0.707 |
|
| 2005 |
Hong W, Nakazawa M, Chen YY, Kori R, Vakoc CR, Rakowski C, Blobel GA. FOG-1 recruits the NuRD repressor complex to mediate transcriptional repression by GATA-1. The Embo Journal. 24: 2367-78. PMID 15920470 DOI: 10.1038/Sj.Emboj.7600703 |
0.762 |
|
| 2005 |
Vakoc CR, Letting DL, Gheldof N, Sawado T, Bender MA, Groudine M, Weiss MJ, Dekker J, Blobel GA. Proximity among distant regulatory elements at the beta-globin locus requires GATA-1 and FOG-1. Molecular Cell. 17: 453-62. PMID 15694345 DOI: 10.1016/J.Molcel.2004.12.028 |
0.812 |
|
| 2005 |
Dore LC, Vakoc CR, Blobel GA, Hardison RC, Bodine DM, Gallagher PG, Weiss MJ. Genomic Organization, Chromatin Structure, and Transcriptional Regulation of the Murine Alpha Hemoglobin Stabilizing Protein (AHSP) Gene. Blood. 106: 3633-3633. DOI: 10.1182/Blood.V106.11.3633.3633 |
0.741 |
|
| 2005 |
Vakoc CR, Mandat SA, Olenschock BA, Blobel GA. Histone H3 Lysine 9 Methylation and HP1γ Are Associated with Transcription Elongation through Mammalian Chromatin. Blood. 106: 1734-1734. DOI: 10.1182/Blood.V106.11.1734.1734 |
0.735 |
|
| 2004 |
Patel JH, Du Y, Ard PG, Phillips C, Carella B, Chen CJ, Rakowski C, Chatterjee C, Lieberman PM, Lane WS, Blobel GA, McMahon SB. The c-MYC oncoprotein is a substrate of the acetyltransferases hGCN5/PCAF and TIP60. Molecular and Cellular Biology. 24: 10826-34. PMID 15572685 DOI: 10.1128/Mcb.24.24.10826-10834.2004 |
0.468 |
|
| 2004 |
Bayly R, Chuen L, Currie RA, Hyndman BD, Casselman R, Blobel GA, LeBrun DP. E2A-PBX1 interacts directly with the KIX domain of CBP/p300 in the induction of proliferation in primary hematopoietic cells. The Journal of Biological Chemistry. 279: 55362-71. PMID 15507449 DOI: 10.1074/Jbc.M408654200 |
0.424 |
|
| 2004 |
Song S, Cooperman J, Letting DL, Blobel GA, Choi JK. Identification of cyclin D3 as a direct target of E2A using DamID. Molecular and Cellular Biology. 24: 8790-802. PMID 15367695 DOI: 10.1128/Mcb.24.19.8790-8802.2004 |
0.832 |
|
| 2004 |
Welch JJ, Watts JA, Vakoc CR, Yao Y, Wang H, Hardison RC, Blobel GA, Chodosh LA, Weiss MJ. Global regulation of erythroid gene expression by transcription factor GATA-1. Blood. 104: 3136-47. PMID 15297311 DOI: 10.1182/Blood-2004-04-1603 |
0.75 |
|
| 2004 |
Anguita E, Hughes J, Heyworth C, Blobel GA, Wood WG, Higgs DR. Globin gene activation during haemopoiesis is driven by protein complexes nucleated by GATA-1 and GATA-2. The Embo Journal. 23: 2841-52. PMID 15215894 DOI: 10.1038/Sj.Emboj.7600274 |
0.547 |
|
| 2004 |
Letting DL, Chen YY, Rakowski C, Reedy S, Blobel GA. Context-dependent regulation of GATA-1 by friend of GATA-1. Proceedings of the National Academy of Sciences of the United States of America. 101: 476-81. PMID 14695898 DOI: 10.1073/Pnas.0306315101 |
0.857 |
|
| 2004 |
Oravecz T, Turner A, Brown P, Zambrowicz B, Blobel G. Genetic Modeling of Chemical Antagonists: Genome Scale Validation of Hematopoietic Disease Drug Targets by In Vivo Functional Analysis. Blood. 104: 2577-2577. DOI: 10.1182/Blood.V104.11.2577.2577 |
0.35 |
|
| 2004 |
Choi JK, Song S, Cooperman J, Letting DL, Blobel GA. Identification of Cyclin D3 as a Direct Transcriptional Target of E2A Using Damid. Blood. 104: 1618-1618. DOI: 10.1182/Blood.V104.11.1618.1618 |
0.842 |
|
| 2004 |
Vakoc C, Dekker J, Blobel GA. GATA-1 Directly Induces Physical Proximity between the LCR and β Globin Promoter in Erythroid Cells. Blood. 104: 1612-1612. DOI: 10.1182/Blood.V104.11.1612.1612 |
0.737 |
|
| 2003 |
Rylski M, Welch JJ, Chen YY, Letting DL, Diehl JA, Chodosh LA, Blobel GA, Weiss MJ. GATA-1-mediated proliferation arrest during erythroid maturation. Molecular and Cellular Biology. 23: 5031-42. PMID 12832487 DOI: 10.1128/Mcb.23.14.5031-5042.2003 |
0.845 |
|
| 2003 |
Deng Z, Chen CJ, Chamberlin M, Lu F, Blobel GA, Speicher D, Cirillo LA, Zaret KS, Lieberman PM. The CBP bromodomain and nucleosome targeting are required for Zta-directed nucleosome acetylation and transcription activation. Molecular and Cellular Biology. 23: 2633-44. PMID 12665567 DOI: 10.1128/Mcb.23.8.2633-2644.2003 |
0.503 |
|
| 2003 |
Letting DL, Rakowski C, Weiss MJ, Blobel GA. Formation of a tissue-specific histone acetylation pattern by the hematopoietic transcription factor GATA-1. Molecular and Cellular Biology. 23: 1334-40. PMID 12556492 DOI: 10.1128/Mcb.23.4.1334-1340.2003 |
0.86 |
|
| 2002 |
Hong W, Resnick RJ, Rakowski C, Shalloway D, Taylor SJ, Blobel GA. Physical and functional interaction between the transcriptional cofactor CBP and the KH domain protein Sam68. Molecular Cancer Research : McR. 1: 48-55. PMID 12496368 |
0.353 |
|
| 2002 |
Wang X, Crispino JD, Letting DL, Nakazawa M, Poncz M, Blobel GA. Control of megakaryocyte-specific gene expression by GATA-1 and FOG-1: role of Ets transcription factors. The Embo Journal. 21: 5225-34. PMID 12356738 DOI: 10.1093/Emboj/Cdf527 |
0.852 |
|
| 2002 |
Johnson KD, Grass JA, Boyer ME, Kiekhaefer CM, Blobel GA, Weiss MJ, Bresnick EH. Cooperative activities of hematopoietic regulators recruit RNA polymerase II to a tissue-specific chromatin domain. Proceedings of the National Academy of Sciences of the United States of America. 99: 11760-5. PMID 12193659 DOI: 10.1073/Pnas.192285999 |
0.454 |
|
| 2002 |
Kihm AJ, Kong Y, Hong W, Russell JE, Rouda S, Adachl K, Simon MC, Blobel GA, Weiss MJ. An abundant erythroid protein that stabilizes free α-haemoglobin Nature. 417: 758-763. PMID 12066189 DOI: 10.1038/Nature00803 |
0.32 |
|
| 2002 |
Hong W, Kim AY, Ky S, Rakowski C, Seo SB, Chakravarti D, Atchison M, Blobel GA. Inhibition of CBP-mediated protein acetylation by the Ets family oncoprotein PU.1 Molecular and Cellular Biology. 22: 3729-3743. PMID 11997509 DOI: 10.1128/Mcb.22.11.3729-3743.2002 |
0.562 |
|
| 2002 |
Blobel GA. CBP and p300: Versatile coregulators with important roles in hematopoietic gene expression Journal of Leukocyte Biology. 71: 545-556. PMID 11927640 DOI: 10.1189/Jlb.71.4.545 |
0.385 |
|
| 2001 |
Chen CJ, Deng Z, Kim AY, Blobel GA, Lieberman PM. Stimulation of CREB binding protein nucleosomal histone acetyltransferase activity by a class of transcriptional activators Molecular and Cellular Biology. 21: 476-487. PMID 11134336 DOI: 10.1128/Mcb.21.2.476-487.2001 |
0.556 |
|
| 2001 |
Hung HL, Kim AY, Hong W, Rakowski C, Blobel GA. Stimulation of NF-E2 DNA Binding by CREB-binding Protein (CBP)-mediated Acetylation Journal of Biological Chemistry. 276: 10715-10721. DOI: 10.1074/Jbc.M007846200 |
0.531 |
|
| 2000 |
Blobel GA. CREB-binding protein and p300: Molecular integrators of hematopoietic transcription Blood. 95: 745-755. PMID 10648382 DOI: 10.1182/Blood.V95.3.745.003K05_745_755 |
0.513 |
|
| 1999 |
Gregory T, Yu C, Ma A, Orkin SH, Blobel GA, Weiss MJ. GATA-1 and erythropoietin cooperate to promote erythroid cell survival by regulating bcl-x(L) expression Blood. 94: 87-96. PMID 10381501 |
0.681 |
|
| 1999 |
Hung HL, Lau J, Kim AY, Weiss MJ, Blobel GA. CREB-Binding protein acetylates hematopoietic transcription factor GATA- 1 at functionally important sites Molecular and Cellular Biology. 19: 3496-3505. PMID 10207073 DOI: 10.1128/Mcb.19.5.3496 |
0.576 |
|
| 1999 |
Gregory T, Yu C, Ma A, Orkin SH, Blobel GA, Weiss MJ. GATA-1 and Erythropoietin Cooperate to Promote Erythroid Cell Survival by Regulating bcl-xL Expression Blood. 94: 87-96. DOI: 10.1182/Blood.V94.1.87.413K41_87_96 |
0.708 |
|
| 1998 |
Blobel GA, Nakajima T, Eckner R, Montminy M, Orkin SH. CREB-binding protein cooperates with transcription factor GATA-1 and is required for erythroid differentiation Proceedings of the National Academy of Sciences of the United States of America. 95: 2061-2066. PMID 9482838 DOI: 10.1073/Pnas.95.5.2061 |
0.69 |
|
| 1996 |
Blobel GA, Orkin SH. Estrogen-induced apoptosis by inhibition of the erythroid transcription factor GATA-1 Molecular and Cellular Biology. 16: 1687-1694. PMID 8657144 DOI: 10.1128/Mcb.16.4.1687 |
0.508 |
|
| 1995 |
Blobel GA, Simon MC, Orkin SH. Rescue of GATA-1-deficient embryonic stem cells by heterologous GATA- binding proteins Molecular and Cellular Biology. 15: 626-633. PMID 7823931 DOI: 10.1128/Mcb.15.2.626 |
0.601 |
|
| 1995 |
Blobel GA, Sieff CA, Orkin SH. Ligand-dependent repression of the erythroid transcription factor GATA-1 by the estrogen receptor Molecular and Cellular Biology. 15: 3147-3153. PMID 7760810 DOI: 10.1128/Mcb.15.6.3147 |
0.573 |
|
| 1991 |
Blobel GA, Hanafusa H. The v-src inducible gene 9E3/pCEF4 is regulated by both its promoter upstream sequence and its 3′ untranslated region Proceedings of the National Academy of Sciences of the United States of America. 88: 1162-1166. PMID 1996318 DOI: 10.1073/Pnas.88.4.1162 |
0.338 |
|
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