| Year |
Citation |
Score |
| 2024 |
Pan F, Zhou Q, Yan M, Yang S, Hu R, Chen Y, Wen Y, Chao Y, Xie C, Ou W, Li Y, Zhang H, Guo D, Zhang X. Development of pyrimidone derivatives as nonpeptidic and noncovalent 3-chymotrypsin-like protease (3CL) inhibitors with anti-coronavirus activities. Bioorganic Chemistry. 154: 107988. PMID 39591689 DOI: 10.1016/j.bioorg.2024.107988 |
0.464 |
|
| 2024 |
Chen Q, Zhou Q, Yang S, Pan F, Tao H, Wen Y, Chao Y, Xie C, Ou W, Guo D, Li Y, Zhang X. Identification of adenosine analogues as nsp14 N7‑methyltransferase inhibitors for treating coronaviruses infection. Bioorganic Chemistry. 153: 107894. PMID 39490138 DOI: 10.1016/j.bioorg.2024.107894 |
0.488 |
|
| 2024 |
Chen Y, Zhou Q, Pan F, Rong B, Xiao R, Wen Y, Song J, Tu Z, Liu S, Li Y, Zhang X. Synthesis and anti-influenza virus activity of substituted dibenzoxepine-based baloxavir derivatives. European Journal of Medicinal Chemistry. 280: 116922. PMID 39388905 DOI: 10.1016/j.ejmech.2024.116922 |
0.44 |
|
| 2024 |
Wang A, Wang Y, Liang R, Li B, Pan F. Improving regulatory T cell-based therapy: insights into post-translational modification regulation. Journal of Genetics and Genomics = Yi Chuan Xue Bao. PMID 39357622 DOI: 10.1016/j.jgg.2024.09.014 |
0.304 |
|
| 2023 |
Riaz F, Wei P, Pan F. PPARs at the crossroads of T cell differentiation and type 1 diabetes. Frontiers in Immunology. 14: 1292238. PMID 37928539 DOI: 10.3389/fimmu.2023.1292238 |
0.314 |
|
| 2023 |
Wei P, Kou W, Riaz F, Zhang K, Fu J, Pan F. Combination therapy of HIFα inhibitors and Treg depletion strengthen the anti-tumor immunity in mice. European Journal of Immunology. e2250182. PMID 37615189 DOI: 10.1002/eji.202250182 |
0.341 |
|
| 2023 |
Wei P, Kou W, Fu J, Chen Z, Pan F. Pparα knockout in mice increases the Th17 development by facilitating the IKKα/RORγt and IKKα/Foxp3 complexes. Communications Biology. 6: 721. PMID 37452099 DOI: 10.1038/s42003-023-05104-6 |
0.306 |
|
| 2021 |
Dong Y, Yang C, Pan F. Post-Translational Regulations of Foxp3 in Treg Cells and Their Therapeutic Applications. Frontiers in Immunology. 12: 626172. PMID 33912156 DOI: 10.3389/fimmu.2021.626172 |
0.308 |
|
| 2021 |
Dong Y, Pan F. Ubiquitin-Dependent Regulation of Treg Function and Plasticity. Advances in Experimental Medicine and Biology. 1278: 63-80. PMID 33523443 DOI: 10.1007/978-981-15-6407-9_4 |
0.334 |
|
| 2020 |
Samanta D, Huang TY, Shah R, Yang Y, Pan F, Semenza GL. BIRC2 Expression Impairs Anti-Cancer Immunity and Immunotherapy Efficacy. Cell Reports. 32: 108073. PMID 32846130 DOI: 10.1016/J.Celrep.2020.108073 |
0.407 |
|
| 2020 |
Yang J, Wei P, Barbi J, Huang Q, Yang E, Bai Y, Nie J, Gao Y, Tao J, Lu Y, Xie C, Hou X, Ren J, Wu X, Meng J, ... ... Pan F, et al. The deubiquitinase USP44 promotes Treg function during inflammation by preventing FOXP3 degradation. Embo Reports. e50308. PMID 32644293 DOI: 10.15252/Embr.202050308 |
0.409 |
|
| 2020 |
Hurwitz LM, Kulac I, Gumuskaya B, Baena Del Valle JA, Benedetti I, Pan F, Liu JO, Marrone MT, Arnold KB, Goodman PJ, Tangen CM, Lucia MS, Thompson IM, Drake CG, Isaacs WB, et al. Use of Aspirin and Statins in Relation to Inflammation in Benign Prostate Tissue in the Placebo Arm of the Prostate Cancer Prevention Trial. Cancer Prevention Research (Philadelphia, Pa.). PMID 32581009 DOI: 10.1158/1940-6207.Capr-19-0450 |
0.31 |
|
| 2020 |
Morianos I, Trochoutsou AI, Papadopoulou G, Semitekolou M, Banos A, Konstantopoulos D, Manousopoulou A, Kapasa M, Wei P, Lomenick B, Belaidi E, Kalamatas T, Karageorgiou K, Doskas T, Sallusto F, ... Pan F, et al. Activin-A limits Th17 pathogenicity and autoimmune neuroinflammation via CD39 and CD73 ectonucleotidases and Hif1-α-dependent pathways. Proceedings of the National Academy of Sciences of the United States of America. PMID 32409602 DOI: 10.1073/Pnas.1918196117 |
0.381 |
|
| 2020 |
Lebid A, Chung L, Pardoll DM, Pan F. YAP Attenuates CD8 T Cell-Mediated Anti-tumor Response. Frontiers in Immunology. 11: 580. PMID 32322254 DOI: 10.3389/Fimmu.2020.00580 |
0.429 |
|
| 2019 |
Fleskens V, Minutti CM, Wu X, Wei P, Pals CEGM, McCrae J, Hemmers S, Groenewold V, Vos HJ, Rudensky A, Pan F, Li H, Zaiss DM, Coffer PJ. Nemo-like Kinase Drives Foxp3 Stability and Is Critical for Maintenance of Immune Tolerance by Regulatory T Cells. Cell Reports. 26: 3600-3612.e6. PMID 30917315 DOI: 10.1016/J.Celrep.2019.02.087 |
0.448 |
|
| 2019 |
Ni X, Kou W, Gu J, Wei P, Wu X, Peng H, Tao J, Yan W, Yang X, Lebid A, Park BV, Chen Z, Tian Y, Fu J, Newman S, ... ... Pan F, et al. TRAF6 directs FOXP3 localization and facilitates regulatory T-cell function through K63-linked ubiquitination. The Embo Journal. PMID 30886050 DOI: 10.15252/Embj.201899766 |
0.422 |
|
| 2019 |
Wolf MT, Ganguly S, Wang TL, Anderson CW, Sadtler K, Narain R, Cherry C, Parrillo AJ, Park BV, Wang G, Pan F, Sukumar S, Pardoll DM, Elisseeff JH. A biologic scaffold-associated type 2 immune microenvironment inhibits tumor formation and synergizes with checkpoint immunotherapy. Science Translational Medicine. 11. PMID 30700576 DOI: 10.1126/Scitranslmed.Aat7973 |
0.34 |
|
| 2018 |
Ni X, Tao J, Barbi J, Chen Q, Park BV, Li Z, Zhang N, Lebid A, Ramaswamy A, Wei P, Zheng Y, Zhang X, Wu X, Vignali PDA, Yang C, ... ... Pan F, et al. YAP is essential for Treg mediated suppression of anti-tumor immunity. Cancer Discovery. PMID 29907586 DOI: 10.1158/2159-8290.Cd-17-1124 |
0.406 |
|
| 2018 |
Samanta D, Park Y, Ni X, Li H, Zahnow CA, Gabrielson E, Pan F, Semenza GL. Chemotherapy induces enrichment of CD47+/CD73+/PDL1+ immune evasive triple-negative breast cancer cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 29367423 DOI: 10.1073/Pnas.1718197115 |
0.357 |
|
| 2017 |
Vignali PDA, Barbi J, Pan F. Metabolic Regulation of T Cell Immunity. Advances in Experimental Medicine and Biology. 1011: 87-130. PMID 28875487 DOI: 10.1007/978-94-024-1170-6_2 |
0.369 |
|
| 2017 |
Lu L, Barbi J, Pan F. The regulation of immune tolerance by FOXP3. Nature Reviews. Immunology. PMID 28757603 DOI: 10.1038/Nri.2017.75 |
0.409 |
|
| 2016 |
Tao JH, Cheng M, Tang JP, Liu Q, Pan F, Li XP. Foxp3, Regulatory T Cell, and Autoimmune Diseases. Inflammation. PMID 27882473 DOI: 10.1007/S10753-016-0470-8 |
0.396 |
|
| 2016 |
Park BV, Freeman ZT, Ghasemzadeh A, Chattergoon MA, Rutebemberwa A, Steigner J, Winter ME, Huynh TV, Sebald SM, Lee SJ, Pan F, Pardoll DM, Cox AL. TGF-β1-Mediated Smad3 Enhances PD-1 Expression on Antigen-Specific T Cells in Cancer. Cancer Discovery. PMID 27683557 DOI: 10.1158/2159-8290.Cd-15-1347 |
0.351 |
|
| 2016 |
Yang HY, Barbi J, Wu CY, Zheng Y, Vignali PD, Wu X, Tao JH, Park BV, Bandara S, Novack L, Ni X, Yang X, Chang KY, Wu RC, Zhang J, ... ... Pan F, et al. MicroRNA-17 Modulates Regulatory T Cell Function by Targeting Co-regulators of the Foxp3 Transcription Factor. Immunity. 45: 83-93. PMID 27438767 DOI: 10.1016/J.Immuni.2016.06.022 |
0.345 |
|
| 2015 |
Tao JH, Barbi J, Pan F. Effect of hypoxia on T cell differentiation. A Review in the Theme: Cellular Responses to Hypoxia. American Journal of Physiology. Cell Physiology. ajpcell.00204.2015. PMID 26354751 DOI: 10.1152/Ajpcell.00204.2015 |
0.371 |
|
| 2015 |
Barbi J, Pardoll DM, Pan F. Ubiquitin-dependent regulation of Foxp3 and Treg function. Immunological Reviews. 266: 27-45. PMID 26085205 DOI: 10.1111/Imr.12312 |
0.428 |
|
| 2015 |
Mascanfroni ID, Takenaka MC, Yeste A, Patel B, Wu Y, Kenison JE, Siddiqui S, Basso AS, Otterbein LE, Pardoll DM, Pan F, Priel A, Clish CB, Robson SC, Quintana FJ. Metabolic control of type 1 regulatory T cell differentiation by AHR and HIF1-α. Nature Medicine. 21: 638-46. PMID 26005855 DOI: 10.1038/Nm.3868 |
0.375 |
|
| 2015 |
Nakanishi T, Xu X, Wynn C, Yamada T, Pan F, Erickson L, Teo H, Nakagawa T, Masunaga T, Abe J, Akamatsu M, Tamura K, Jiang H. Absence of Activation-Induced Cytidine Deaminase, a Regulator of Class Switch Recombination and Hypermutation in B Cells, Suppresses Aorta Allograft Vasculopathy in Mice. Transplantation. PMID 25769064 DOI: 10.1097/Tp.0000000000000688 |
0.733 |
|
| 2014 |
Pan F, Barbi J. Ubiquitous points of control over regulatory T cells. Journal of Molecular Medicine (Berlin, Germany). 92: 555-69. PMID 24777637 DOI: 10.1007/S00109-014-1156-Z |
0.426 |
|
| 2014 |
Barbi J, Pardoll D, Pan F. Treg functional stability and its responsiveness to the microenvironment. Immunological Reviews. 259: 115-39. PMID 24712463 DOI: 10.1111/Imr.12172 |
0.365 |
|
| 2013 |
Chen Z, Barbi J, Bu S, Yang HY, Li Z, Gao Y, Jinasena D, Fu J, Lin F, Chen C, Zhang J, Yu N, Li X, Shan Z, Nie J, ... ... Pan F, et al. The ubiquitin ligase Stub1 negatively modulates regulatory T cell suppressive activity by promoting degradation of the transcription factor Foxp3. Immunity. 39: 272-85. PMID 23973223 DOI: 10.1016/J.Immuni.2013.08.006 |
0.446 |
|
| 2013 |
van Loosdregt J, Fleskens V, Fu J, Brenkman AB, Bekker CP, Pals CE, Meerding J, Berkers CR, Barbi J, Gröne A, Sijts AJ, Maurice MM, Kalkhoven E, Prakken BJ, Ovaa H, ... Pan F, et al. Stabilization of the transcription factor Foxp3 by the deubiquitinase USP7 increases Treg-cell-suppressive capacity. Immunity. 39: 259-71. PMID 23973222 DOI: 10.1016/J.Immuni.2013.05.018 |
0.431 |
|
| 2013 |
Sharma MD, Huang L, Choi JH, Lee EJ, Wilson JM, Lemos H, Pan F, Blazar BR, Pardoll DM, Mellor AL, Shi H, Munn DH. An inherently bifunctional subset of Foxp3+ T helper cells is controlled by the transcription factor eos. Immunity. 38: 998-1012. PMID 23684987 DOI: 10.1016/J.Immuni.2013.01.013 |
0.409 |
|
| 2013 |
Vasquez-Dunddel D, Pan F, Zeng Q, Gorbounov M, Albesiano E, Fu J, Blosser RL, Tam AJ, Bruno T, Zhang H, Pardoll D, Kim Y. STAT3 regulates arginase-I in myeloid-derived suppressor cells from cancer patients. The Journal of Clinical Investigation. 123: 1580-9. PMID 23454751 DOI: 10.1172/Jci60083 |
0.406 |
|
| 2013 |
Barbi J, Pardoll D, Pan F. Metabolic control of the Treg/Th17 axis. Immunological Reviews. 252: 52-77. PMID 23405895 DOI: 10.1111/Imr.12029 |
0.394 |
|
| 2012 |
See AP, Han JE, Phallen J, Binder Z, Gallia G, Pan F, Jinasena D, Jackson C, Belcaid Z, Jeong SJ, Gottschalk C, Zeng J, Ruzevick J, Nicholas S, Kim Y, et al. The role of STAT3 activation in modulating the immune microenvironment of GBM. Journal of Neuro-Oncology. 110: 359-68. PMID 23096132 DOI: 10.1007/S11060-012-0981-6 |
0.409 |
|
| 2012 |
Pan F, Fan H, Liu Z, Jiang S. T cell signaling targets for enhancing regulatory or effector function. Science Signaling. 5: pe32. PMID 22855503 DOI: 10.1126/scisignal.2003364 |
0.347 |
|
| 2012 |
Pan F, Barbi J, Pardoll DM. Hypoxia-inducible factor 1: A link between metabolism and T cell differentiation and a potential therapeutic target. Oncoimmunology. 1: 510-515. PMID 22754770 DOI: 10.4161/Onci.19457 |
0.383 |
|
| 2012 |
Erickson L, Wynn C, Pan F, Crews G, Xia G, Yamada T, Xu X, Tu Y, Huang D, Song Y, Tamura K, Jiang H. Microarray gene expression profiling of chronic allograft nephropathy in the rat kidney transplant model. Transplant Immunology. 27: 75-82. PMID 22732363 DOI: 10.1016/J.Trim.2012.06.007 |
0.726 |
|
| 2012 |
Bettini ML, Pan F, Bettini M, Finkelstein D, Rehg JE, Floess S, Bell BD, Ziegler SF, Huehn J, Pardoll DM, Vignali DA. Loss of epigenetic modification driven by the Foxp3 transcription factor leads to regulatory T cell insufficiency. Immunity. 36: 717-30. PMID 22579476 DOI: 10.1016/J.Immuni.2012.03.020 |
0.407 |
|
| 2011 |
Dang EV, Barbi J, Yang HY, Jinasena D, Yu H, Zheng Y, Bordman Z, Fu J, Kim Y, Yen HR, Luo W, Zeller K, Shimoda L, Topalian SL, Semenza GL, ... ... Pan F, et al. Control of TH17/Treg balance by hypoxia-inducible factor 1 Cell. 146: 772-784. PMID 21871655 DOI: 10.1016/J.Cell.2011.07.033 |
0.412 |
|
| 2010 |
Getnet D, Grosso JF, Goldberg MV, Harris TJ, Yen HR, Bruno TC, Durham NM, Hipkiss EL, Pyle KJ, Wada S, Pan F, Pardoll DM, Drake CG. A role for the transcription factor Helios in human CD4(+)CD25(+) regulatory T cells. Molecular Immunology. 47: 1595-600. PMID 20226531 DOI: 10.1016/J.Molimm.2010.02.001 |
0.403 |
|
| 2010 |
Xu X, Wynn C, Pan F, Xia G, Yamada T, Tamura K, Jiang H. THE CONTRIBUTIONS OF ALLOANTIBODY, B AND T CELLS TO THE DEVELOPMENT OF ALLOGRAFT VASCULOPATHY AFTER AORTA TRANSPLANTATION IN MICE Transplantation Journal. 90: 486. DOI: 10.1097/00007890-201007272-00901 |
0.308 |
|
| 2009 |
Pan F, Yu H, Dang EV, Barbi J, Pan X, Grosso JF, Jinasena D, Sharma SM, McCadden EM, Getnet D, Drake CG, Liu JO, Ostrowski MC, Pardoll DM. Eos mediates Foxp3-dependent gene silencing in CD4+ regulatory T cells. Science (New York, N.Y.). 325: 1142-6. PMID 19696312 DOI: 10.1126/Science.1176077 |
0.456 |
|
| 2008 |
Ren YR, Pan F, Parvez S, Fleig A, Chong CR, Xu J, Dang Y, Zhang J, Jiang H, Penner R, Liu JO. Clofazimine inhibits human Kv1.3 potassium channel by perturbing calcium oscillation in T lymphocytes. Plos One. 3: e4009. PMID 19104661 DOI: 10.1371/Journal.Pone.0004009 |
0.665 |
|
| 2008 |
Jang MS, Pan F, Erickson LM, Fisniku O, Crews G, Wynn C, Hong IC, Tamura K, Kobayashi M, Jiang H. A blocking anti-CD28-specific antibody induces long-term heart allograft survival by suppression of the PKC theta-JNK signal pathway. Transplantation. 85: 1051-5. PMID 18408588 DOI: 10.1097/Tp.0B013E31816846F6 |
0.736 |
|
| 2007 |
Pan F, Sun L, Kardian DB, Whartenby KA, Pardoll DM, Liu JO. Feedback inhibition of calcineurin and Ras by a dual inhibitory protein Carabin. Nature. 445: 433-6. PMID 17230191 DOI: 10.1038/Nature05476 |
0.723 |
|
| 2006 |
Chong CR, Qian DZ, Pan F, Wei Y, Pili R, Sullivan DJ, Liu JO. Identification of type 1 inosine monophosphate dehydrogenase as an antiangiogenic drug target. Journal of Medicinal Chemistry. 49: 2677-80. PMID 16640327 DOI: 10.1021/Jm051225T |
0.66 |
|
| 2005 |
Jiang H, Pan F, Erickson LM, Jang MS, Sanui T, Kunisaki Y, Sasazuki T, Kobayashi M, Fukui Y. Deletion of DOCK2, a regulator of the actin cytoskeleton in lymphocytes, suppresses cardiac allograft rejection. The Journal of Experimental Medicine. 202: 1121-30. PMID 16230477 DOI: 10.1084/Jem.20050911 |
0.766 |
|
| 2005 |
Stuart PM, Yin X, Plambeck S, Pan F, Ferguson TA. The role of Fas ligand as an effector molecule in corneal graft rejection. European Journal of Immunology. 35: 2591-7. PMID 16114107 DOI: 10.1002/eji.200425934 |
0.301 |
|
| 2005 |
Pan F, Means AR, Liu JO. Calmodulin-dependent protein kinase IV regulates nuclear export of Cabin1 during T-cell activation. The Embo Journal. 24: 2104-13. PMID 15902271 DOI: 10.1038/Sj.Emboj.7600685 |
0.408 |
|
| 2004 |
Erickson L, Crews G, Pan F, Fisniku O, Jang MS, Wynn C, Kobayashi M, Jiang H. Unique gene expression profiles of heart allograft rejection in the interferon regulatory factor-1-deficient mouse. Transplant Immunology. 13: 169-75. PMID 15381199 DOI: 10.1016/j.trim.2004.06.003 |
0.728 |
|
| 2004 |
Pan F, Ye Z, Cheng L, Liu JO. Myocyte enhancer factor 2 mediates calcium-dependent transcription of the interleukin-2 gene in T lymphocytes: a calcium signaling module that is distinct from but collaborates with the nuclear factor of activated T cells (NFAT). The Journal of Biological Chemistry. 279: 14477-80. PMID 14722108 DOI: 10.1074/Jbc.C300487200 |
0.377 |
|
| 2003 |
Erickson LM, Pan F, Ebbs A, Kobayashi M, Jiang H. Microarray-based gene expression profiles of allograft rejection and immunosuppression in the rat heart transplantation model. Transplantation. 76: 582-8. PMID 12923448 DOI: 10.1097/01.Tp.0000081398.65568.1B |
0.723 |
|
| 2003 |
Han A, Pan F, Stroud JC, Youn HD, Liu JO, Chen L. Sequence-specific recruitment of transcriptional co-repressor Cabin1 by myocyte enhancer factor-2. Nature. 422: 730-4. PMID 12700764 DOI: 10.1038/Nature01555 |
0.624 |
|
| 2002 |
Jiang H, Wynn C, Pan F, Ebbs A, Erickson LM, Kobayashi M. Tacrolimus and cyclosporine differ in their capacity to overcome ongoing allograft rejection as a result of their differential abilities to inhibit interleukin-10 production. Transplantation. 73: 1808-17. PMID 12085006 DOI: 10.1097/00007890-200206150-00019 |
0.724 |
|
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