| Year |
Citation |
Score |
| 2024 |
Zhang Y, Xiong M, Chen Z, Seabra G, Liu J, Li C, Cui L. Design Principle of Heparanase Inhibitors: A Combined In Vitro and In Silico Study. Acs Medicinal Chemistry Letters. 15: 1032-1040. PMID 39015272 DOI: 10.1021/acsmedchemlett.3c00268 |
0.351 |
|
| 2024 |
Li Q, Liu Y, Wu J, Zhu Z, Fan J, Zhai L, Wang Z, Du G, Zhang L, Hu J, Ma DK, Liu JO, Huang H, Tan M, Dang Y, et al. P4HA2 hydroxylates SUFU to regulate the paracrine Hedgehog signaling and promote B-cell lymphoma progression. Leukemia. PMID 38909089 DOI: 10.1038/s41375-024-02313-8 |
0.594 |
|
| 2024 |
Ding H, Chen XC, Wan L, Zhang YY, Rui XH, He T, Liu J, Shang ZB. alters zebrafish circadian rhythm via inflammatory pathways and is dependent on light cues. Heliyon. 10: e30829. PMID 38770281 DOI: 10.1016/j.heliyon.2024.e30829 |
0.421 |
|
| 2024 |
Qiu H, Qian S, Head SA, Sanchez PR, Liu JO, Jin Z. Insights into the structure-activity relationship of the anticancer compound ZJ-101: A role played by the amide moiety. Bioorganic & Medicinal Chemistry Letters. 129741. PMID 38599296 DOI: 10.1016/j.bmcl.2024.129741 |
0.796 |
|
| 2023 |
Fang H, Wang X, Damarla M, Sun R, He Q, Li R, Luo P, Liu JO, Xia Z. Dimethyl Fumarate Protects against Lipopolysaccharide- (LPS-) Induced Sepsis through Inhibition of NF-B Pathway in Mice. Mediators of Inflammation. 2023: 5133505. PMID 37840694 DOI: 10.1155/2023/5133505 |
0.77 |
|
| 2023 |
Reyes Gaido OE, Pavlaki N, Granger JM, Mesubi OO, Liu B, Lin BL, Long A, Walker D, Mayourian J, Schole KL, Terrillion CE, Nkashama LJ, Hulsurkar MM, Dorn LE, Ferrero KM, ... ... Liu JO, et al. An improved reporter identifies ruxolitinib as a potent and cardioprotective CaMKII inhibitor. Science Translational Medicine. 15: eabq7839. PMID 37343080 DOI: 10.1126/scitranslmed.abq7839 |
0.711 |
|
| 2023 |
Qian S, Head SA, Sanchez PR, Liu JO, Jin Z. Synthesis and biological evaluation of biotinylated ZJ-101. Bioorganic & Medicinal Chemistry Letters. 91: 129372. PMID 37301523 DOI: 10.1016/j.bmcl.2023.129372 |
0.797 |
|
| 2023 |
Sanchez PR, Head SA, Qian S, Qiu H, Roy A, Jin Z, Zheng W, Liu JO. Modulation of the Endomembrane System by the Anticancer Natural Product Superstolide/ZJ-101. International Journal of Molecular Sciences. 24. PMID 37298526 DOI: 10.3390/ijms24119575 |
0.811 |
|
| 2023 |
Liu J, Zhang W, Wu S, Zeng T, Luo F, Jiang Q, Yang R. A clinical case report of Balamuthia granulomatous amoebic encephalitis in a non-immunocompromised patient and literature review. Bmc Infectious Diseases. 23: 245. PMID 37072710 DOI: 10.1186/s12879-023-08228-6 |
0.306 |
|
| 2023 |
Xu XL, Lan JX, Huang H, Dai W, Peng XP, Liu SL, Chen WM, Huang LJ, Liu J, Li XJ, Zeng JL, Huang XH, Zhao GN, Hou W. Synthesis, biological activity and mechanism of action of novel allosecurinine derivatives as potential antitumor agents. Bioorganic & Medicinal Chemistry. 82: 117234. PMID 36906964 DOI: 10.1016/j.bmc.2023.117234 |
0.342 |
|
| 2023 |
Zhang Y, Yu Y, Liu X, Miao J, Han Y, Liu J, Wang L. An n-type All-Fused-Ring Molecule with Photoresponse to 1000 nm for Highly Sensitive Near Infrared Photodetector. Advanced Materials (Deerfield Beach, Fla.). e2211714. PMID 36842062 DOI: 10.1002/adma.202211714 |
0.303 |
|
| 2023 |
Wang K, Yu Y, Wang W, Jiang Y, Li Y, Jiang X, Qiao Y, Chen L, Zhao X, Liu J, Yang A, Li J, Zhang R. Targeting the E3 ligase NEDD4 as a novel therapeutic strategy for IGF1 signal pathway-driven gastric cancer. Oncogene. PMID 36774408 DOI: 10.1038/s41388-023-02619-4 |
0.304 |
|
| 2023 |
Sang W, Liu J, Xing Y, Feng C, Hu Q, Lang Y, Li X, Bao J, Jiang H. Transcriptome analysis of hepatopancreas of Chinese grass shrimp, Palaemonetes sinensis, infected by Enterocytospora artemiae. Fish & Shellfish Immunology. 108557. PMID 36669602 DOI: 10.1016/j.fsi.2023.108557 |
0.334 |
|
| 2022 |
Hu RJ, Chen XC, Xu L, Rui XH, Wan L, Lu J, Liu J, Pei H. MiR-181a-5p Delivered by Adipose-Derived Mesenchymal Stem Cell Exosomes Alleviates pneumonia Infection-Induced Lung Injury by Targeting STAT3 Signaling. Mediators of Inflammation. 2022: 5188895. PMID 36570020 DOI: 10.1155/2022/5188895 |
0.462 |
|
| 2022 |
Xu Z, Jia Y, Liu J, Ren X, Yang X, Xia X, Pan X. Naringenin and Quercetin Exert Contradictory Cytoprotective and Cytotoxic Effects on Tamoxifen-Induced Apoptosis in HepG2 Cells. Nutrients. 14. PMID 36558554 DOI: 10.3390/nu14245394 |
0.321 |
|
| 2022 |
Zhou X, Kang Y, Chang Y, Xia S, Wu M, Liu J, Dong D, Zhang W, Chen H, Li H. CRC Therapy Identifies Indian Hedgehog Signaling in Mouse Endometrial Epithelial Cells and Inhibition of Ihh-KLF9 as a Novel Strategy for Treating IUA. Cells. 11. PMID 36552817 DOI: 10.3390/cells11244053 |
0.322 |
|
| 2022 |
Liu J, Chen X, Xu L, Tu F, Rui X, Zhang L, Yan Z, Liu Y, Hu R. Neutrophil membrane-coated nanoparticles exhibit increased antimicrobial activities in an anti-microbial resistant K. pneumonia infection model. Nanomedicine : Nanotechnology, Biology, and Medicine. 48: 102640. PMID 36549558 DOI: 10.1016/j.nano.2022.102640 |
0.44 |
|
| 2022 |
Campbell LE, Anderson AM, Chen Y, Johnson SM, McMahon CE, Liu J. Identification of lipid droplet targeting motifs and mechanisms for lipolytic inhibitors G0S2 and HIG2. Journal of Cell Science. PMID 36420951 DOI: 10.1242/jcs.260236 |
0.305 |
|
| 2022 |
Li H, Zhong D, Luo H, Shi W, Xie S, Qiang H, Zhu L, Gao L, Liu J, Sun S, Ding Z, Yang X, Lu X. Nanobody-based CAR T cells targeting intracellular tumor antigens. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. 156: 113919. PMID 36411612 DOI: 10.1016/j.biopha.2022.113919 |
0.333 |
|
| 2022 |
Liu Y, Tian S, Yi B, Feng Z, Chu T, Liu J, Zhang C, Zhang S, Wang Y. Platycodin D sensitizes -mutant colorectal cancer cells to cetuximab by inhibiting the PI3K/Akt signaling pathway. Frontiers in Oncology. 12: 1046143. PMID 36387129 DOI: 10.3389/fonc.2022.1046143 |
0.317 |
|
| 2022 |
Zhou M, Xu D, Zhang W, Wang Y, Zuo M, Wang S, Liu T, Zhang J, Yin L, Guo Z, Liu J, Tan J. The hepato-cardiac disorders in Tibetan residents with hepatic echinococcosis: A case-control echocardiography study. Journal of Clinical Ultrasound : Jcu. 50: 1251-1259. PMID 36353905 DOI: 10.1002/jcu.23287 |
0.302 |
|
| 2022 |
Park E, Lee C, Park J, Liu J, Hong J, Shin DY, Byun JM, Yun H, Koh Y, Yoon SS. Mitigating the BFL1-mediated antiapoptotic pathway in diffuse large B cell lymphoma by inhibiting HDACs. Leukemia & Lymphoma. 1-12. PMID 36331521 DOI: 10.1080/10428194.2022.2140282 |
0.308 |
|
| 2022 |
Tian Z, Sun C, Liu J. Pelargonidin inhibits vascularization and metastasis of brain gliomas by blocking the PI3K/AKT/mTOR pathway. Journal of Biosciences. 47. PMID 36226369 |
0.331 |
|
| 2022 |
Truax NJ, Ayinde S, Liu JO, Romo D. Total Synthesis of Rameswaralide Utilizing a Pharmacophore-Directed Retrosynthetic Strategy. Journal of the American Chemical Society. PMID 36166374 DOI: 10.1021/jacs.2c08245 |
0.53 |
|
| 2022 |
Wang C, Liu J, Lei H, Li Y, Wu J, Guo B, Hu R, Liu T, Wu J, Ding Y, Hu C, Liang S, Xiao C, Liang X, Huang D, et al. Clinical characteristics and outcomes of newly diagnosed patients with HIV-associated aggressive B-cell NHL in China. Journal of Cellular and Molecular Medicine. PMID 36056692 DOI: 10.1111/jcmm.17534 |
0.324 |
|
| 2022 |
Zhao Y, Lin K, Zhang H, Yuan G, Zhang Y, Pan J, Hong L, Huang Y, Ye Y, Huang L, Chen X, Liu J, Li X, He X, Yue Q, et al. Evaluation of droplet digital PCR rapid detection method and precise diagnosis and treatment for suspected sepsis (PROGRESS): a study protocol for a multi-center pragmatic randomized controlled trial. Bmc Infectious Diseases. 22: 630. PMID 35854212 DOI: 10.1186/s12879-022-07557-2 |
0.32 |
|
| 2022 |
Park H, Kam TI, Peng H, Chou SC, Mehrabani-Tabari AA, Song JJ, Yin X, Karuppagounder SS, Umanah GK, Rao AVS, Choi Y, Aggarwal A, Chang S, Kim H, Byun J, ... Liu JO, et al. PAAN/MIF nuclease inhibition prevents neurodegeneration in Parkinson's disease. Cell. PMID 35545089 DOI: 10.1016/j.cell.2022.04.020 |
0.767 |
|
| 2022 |
Zhang MH, Liu J. Cleavage stimulation factor 2 promotes malignant progression of liver hepatocellular carcinoma by activating phosphatidylinositol 3'-kinase/protein kinase B/mammalian target of rapamycin pathway. Bioengineered. 13: 10047-10060. PMID 35412944 DOI: 10.1080/21655979.2022.2063100 |
0.304 |
|
| 2022 |
Chen W, Qie C, Hu X, Wang L, Jiang J, Liu W, Liu J. A small molecule inhibitor of VSIG-8 prevents its binding to VISTA. Investigational New Drugs. PMID 35404016 DOI: 10.1007/s10637-022-01244-4 |
0.344 |
|
| 2022 |
Wang K, Liu J, Li YL, Li JP, Zhang R. Ubiquitination/de-ubiquitination: A promising therapeutic target for PTEN reactivation in cancer. Biochimica Et Biophysica Acta. Reviews On Cancer. 1877: 188723. PMID 35314212 DOI: 10.1016/j.bbcan.2022.188723 |
0.303 |
|
| 2022 |
Chen BX, Fu H, Gao JD, Zhang YX, Huang WJ, Chen ZJ, Qi-Zhang, Yan SJ, Liu J. Identification of Metabolomic Biomarkers of Seed Vigor and Aging in Hybrid Rice. Rice (New York, N.Y.). 15: 7. PMID 35084595 DOI: 10.1186/s12284-022-00552-w |
0.405 |
|
| 2021 |
Wang Y, Peng H, Guo Z, Ullman BR, Yamamoto K, Hong SY, Liu JO. Influence of stereochemistry on the activity of rapadocin, an isoform-specific inhibitor of the nucleoside transporter ENT1. Chemical Science. 12: 11484-11489. PMID 34667552 DOI: 10.1039/d1sc02295d |
0.814 |
|
| 2021 |
Young DJ, Nguyen B, Li L, Higashimoto T, Levis MJ, Liu JO, Small D. A method for overcoming plasma protein inhibition of tyrosine kinase inhibitors. Blood Cancer Discovery. 2: 532-547. PMID 34589716 DOI: 10.1158/2643-3230.bcd-20-0119 |
0.328 |
|
| 2021 |
Ju R, Chen X, Zhang S, Liu B, Pei H, Tu F, Liu J, Yu H. Plasma exosome-derived fragile-site associated tumor suppressor is a powerful predictor of prognosis in patients with ovarian cancer. Bosnian Journal of Basic Medical Sciences. PMID 34491890 DOI: 10.17305/bjbms.2021.6404 |
0.451 |
|
| 2021 |
Yan Y, Narayan A, Cho S, Cheng Z, Liu JO, Zhu H, Wang G, Wharram B, Lisok A, Brummet M, Saeki H, Huang T, Gabrielson K, Gabrielson E, Cope L, et al. CRYβB2 enhances tumorigenesis through upregulation of nucleolin in triple negative breast cancer. Oncogene. PMID 34341513 DOI: 10.1038/s41388-021-01975-3 |
0.517 |
|
| 2021 |
Zhang L, Chen C, Fu J, Lilley B, Berlinicke C, Hansen B, Ding D, Wang G, Wang T, Shou D, Ye Y, Mulligan T, Emmerich K, Saxena MT, Hall KR, ... ... Liu JO, et al. Large-scale phenotypic drug screen identifies neuroprotectants in zebrafish and mouse models of retinitis pigmentosa. Elife. 10. PMID 34184634 DOI: 10.7554/eLife.57245 |
0.561 |
|
| 2021 |
Tian S, Zheng Y, Xiao S, Luo P, Sun R, Liu J, Xia Z. Ivermectin inhibits cell proliferation and the expression levels of type I collagen, α‑SMA and CCN2 in hypertrophic scar fibroblasts. Molecular Medicine Reports. 24. PMID 33955514 DOI: 10.3892/mmr.2021.12127 |
0.349 |
|
| 2021 |
Hao C, Guo R, Liu J, Hu X, Guo J, Yao Y, Zhao Z, Qi Z, Yin J, Chen L, Wang H, Xu B, Li W. Exome sequencing as the first-tier test for pediatric respiratory diseases: a single-center study. Human Mutation. PMID 33942430 DOI: 10.1002/humu.24216 |
0.346 |
|
| 2021 |
Shi X, Jiang L, Zhao X, Chen B, Shi W, Cao Y, Chen Y, Li X, He Y, Li C, Liu X, Li X, Lu H, Chen C, Liu J. Adipose-Derived Stromal Cell-Sheets Sandwiched, Book-Shaped Acellular Dermal Matrix Capable of Sustained Release of Basic Fibroblast Growth Factor Promote Diabetic Wound Healing. Frontiers in Cell and Developmental Biology. 9: 646967. PMID 33842472 DOI: 10.3389/fcell.2021.646967 |
0.333 |
|
| 2021 |
Xie X, Chen C, Chen W, Jiang J, Wang L, Li T, Sun H, Liu J. Structural Basis of VSIG3: The Ligand for VISTA. Frontiers in Immunology. 12: 625808. PMID 33841409 DOI: 10.3389/fimmu.2021.625808 |
0.332 |
|
| 2021 |
Wang H, Tang H, Fang Y, Tan L, Yin J, Shen Y, Zeng Z, Zhu J, Hou Y, Du M, Jiao J, Jiang H, Gong L, Li Z, Liu J, et al. Morbidity and Mortality of Patients Who Underwent Minimally Invasive Esophagectomy After Neoadjuvant Chemoradiotherapy vs Neoadjuvant Chemotherapy for Locally Advanced Esophageal Squamous Cell Carcinoma: A Randomized Clinical Trial. Jama Surgery. PMID 33729467 DOI: 10.1001/jamasurg.2021.0133 |
0.308 |
|
| 2021 |
Wan L, Chen X, Deng J, Zhang S, Tu F, Pei H, Hu R, Liu J, Yu H. Plasma exosome-derived B-cell translation gene 1: a predictive marker for the prognosis in patients with non-small cell lung cancer. Journal of Cancer. 12: 1538-1547. PMID 33531999 DOI: 10.7150/jca.52320 |
0.453 |
|
| 2020 |
Zhuang Q, Li F, Liu J, Wang H, Tian Y, Zhang Z, Wang F, Zhao Z, Chen J, Wu H. Nuclear exclusion of YAP exacerbates podocyte apoptosis and disease progression in Adriamycin-induced focal segmental glomerulosclerosis. Laboratory Investigation; a Journal of Technical Methods and Pathology. 101: 258-270. PMID 33203894 DOI: 10.1038/s41374-020-00503-3 |
0.634 |
|
| 2020 |
Zhuang Q, Li F, Liu J, Wang H, Tian Y, Zhang Z, Wang F, Zhao Z, Chen J, Wu H. Nuclear exclusion of YAP exacerbates podocyte apoptosis and disease progression in Adriamycin-induced focal segmental glomerulosclerosis. Laboratory Investigation; a Journal of Technical Methods and Pathology. 101: 258-270. PMID 33203894 DOI: 10.1038/s41374-020-00503-3 |
0.634 |
|
| 2020 |
Zhuang Q, Li F, Liu J, Wang H, Tian Y, Zhang Z, Wang F, Zhao Z, Chen J, Wu H. Nuclear exclusion of YAP exacerbates podocyte apoptosis and disease progression in Adriamycin-induced focal segmental glomerulosclerosis. Laboratory Investigation; a Journal of Technical Methods and Pathology. 101: 258-270. PMID 33203894 DOI: 10.1038/s41374-020-00503-3 |
0.634 |
|
| 2020 |
Tong L, Zhao Q, Datan E, Lin GQ, Minn I, Pomper MG, Yu B, Romo D, He QL, Liu JO. Triptolide: reflections on two decades of research and prospects for the future. Natural Product Reports. PMID 33146205 DOI: 10.1039/d0np00054j |
0.782 |
|
| 2020 |
Liu J, Li L, Li X, Wang X, Zhao X, Qiao Y, Xu Y, Sun Y, Qian L, Liu Z, Ji A, Lou H. Discovery of lysosome-targeted covalent anticancer agents based on isosteviol skeleton. European Journal of Medicinal Chemistry. 112896. PMID 33097300 DOI: 10.1016/j.ejmech.2020.112896 |
0.331 |
|
| 2020 |
Datan E, Minn I, Xu P, He QL, Ahn HH, Yu B, Pomper MG, Liu JO. A Glucose-Triptolide Conjugate Selectively Targets Cancer Cells under Hypoxia. Iscience. 23: 101536. PMID 33083765 DOI: 10.1016/J.Isci.2020.101536 |
0.81 |
|
| 2020 |
Dai Y, Hartke R, Li C, Yang Q, Liu JO, Wang LX. Synthetic Fluorinated L-Fucose Analogs Inhibit Proliferation of Cancer Cells and Primary Endothelial Cells. Acs Chemical Biology. PMID 32930566 DOI: 10.1021/Acschembio.0C00228 |
0.803 |
|
| 2020 |
Lu L, Jiang J, Zhan M, Zhang H, Wang QT, Sun SN, Guo XK, Yin H, Wei Y, Li SY, Liu JO, Li Y, He YW. Targeting Tumor-Associated Antigens in Hepatocellular Carcinoma for Immunotherapy: Past Pitfalls and Future Strategies. Hepatology (Baltimore, Md.). PMID 32767586 DOI: 10.1002/Hep.31502 |
0.306 |
|
| 2020 |
Li Z, Tan J, Liu X, Zhang W, Meng Q, Zhou M, Lin N, Cao F, Lu J, Liu J, Yin L. Tibetan patients with hepatic hydatidosis can tolerate hypoxic environment without incident increase of pulmonary hypertension: an echocardiography study. The International Journal of Cardiovascular Imaging. PMID 32767023 DOI: 10.1007/s10554-020-01922-5 |
0.301 |
|
| 2020 |
Hurwitz LM, Kulac I, Gumuskaya B, Baena Del Valle JA, Benedetti I, Pan F, Liu JO, Marrone MT, Arnold KB, Goodman PJ, Tangen CM, Lucia MS, Thompson IM, Drake CG, Isaacs WB, et al. Use of Aspirin and Statins in Relation to Inflammation in Benign Prostate Tissue in the Placebo Arm of the Prostate Cancer Prevention Trial. Cancer Prevention Research (Philadelphia, Pa.). PMID 32581009 DOI: 10.1158/1940-6207.Capr-19-0450 |
0.547 |
|
| 2020 |
Li Y, Pasunooti KK, Peng H, Li RJ, Shi WQ, Liu W, Cheng Z, Head SA, Liu JO. Design and Synthesis of Tetrazole- and Pyridine-Containing Itraconazole Analogs as Potent Angiogenesis Inhibitors. Acs Medicinal Chemistry Letters. 11: 1111-1117. PMID 32550989 DOI: 10.1021/Acsmedchemlett.9B00438 |
0.821 |
|
| 2020 |
Li M, Liu S, Chen H, Zhou X, Zhou J, Zhou S, Yuan H, Xu QL, Liu J, Cheng K, Sun H, Wang Y, Chen C, Wen X. N-benzylpiperidinol derivatives as novel USP7 inhibitors: Structure-activity relationships and X-ray crystallographic studies. European Journal of Medicinal Chemistry. 199: 112279. PMID 32497973 DOI: 10.1016/j.ejmech.2020.112279 |
0.309 |
|
| 2020 |
Liu J, Cao C. Evaluation of a GSH-targeting prodrug via a sulfonamide-induced "integrative" platform for selective cancer therapy. The Analyst. PMID 32478783 DOI: 10.1039/d0an00627k |
0.305 |
|
| 2020 |
Ma X, Claus LAN, Leslie ME, Tao K, Wu Z, Liu J, Yu X, Li B, Zhou J, Savatin DV, Peng J, Tyler BM, Heese A, Russinova E, He P, et al. Ligand-induced monoubiquitination of BIK1 regulates plant immunity. Nature. 581: 199-203. PMID 32404997 DOI: 10.1038/S41586-020-2210-3 |
0.302 |
|
| 2020 |
Cui Z, Liu Y, Wan W, Xu Y, Hu Y, Ding M, Dou X, Wang R, Li H, Meng Y, Li W, Jiang W, Li Z, Li Y, Tan M, ... ... Liu JO, et al. Ethacrynic acid targets GSTM1 to ameliorate obesity by promoting browning of white adipocytes. Protein & Cell. PMID 32399897 DOI: 10.1007/S13238-020-00717-7 |
0.601 |
|
| 2020 |
Lu L, Jiang J, Zhan M, Zhang H, Wang QT, Sun SN, Guo XK, Yin H, Wei Y, Liu JO, Li SY, Li Y, He YW. Targeting Neoantigens in Hepatocellular Carcinoma for Immunotherapy: A Futile Strategy? Hepatology (Baltimore, Md.). PMID 32299136 DOI: 10.1002/Hep.31279 |
0.33 |
|
| 2019 |
Liberti MV, Allen AE, Ramesh V, Dai Z, Singleton KR, Guo Z, Liu JO, Wood KC, Locasale JW. Evolved resistance to partial GAPDH inhibition results in loss of the Warburg effect and in a different state of glycolysis. The Journal of Biological Chemistry. PMID 31748414 DOI: 10.1074/Jbc.Ra119.010903 |
0.716 |
|
| 2019 |
Liu JO, Guo Z, Cheng Z, Wang J, Liu W, Peng H, Wang Y, Rao S, Li R, Ying X, Korangath P, Liberti M, Li Y, Xie Y, Hong S, et al. Discovery of a potent GLUT inhibitor using rapafucin 3D microarrays. Angewandte Chemie (International Ed. in English). PMID 31591797 DOI: 10.1002/Anie.201905578 |
0.81 |
|
| 2019 |
Wang Y, Peiffer BJ, Su Q, Liu JO. One-step Heck Reaction Generates Nonimmunosuppressive FK506 Analogs for Pharmacological BMP Activation. Acs Medicinal Chemistry Letters. 10: 1279-1283. PMID 31531197 DOI: 10.1021/Acsmedchemlett.9B00144 |
0.8 |
|
| 2019 |
Truax NJ, Ayinde S, Van K, Liu JO, Romo D. Pharmacophore-Directed Retrosynthesis Applied to Rameswaralide: Synthesis and Bioactivity of Natural Product Tricyclic Cores. Organic Letters. PMID 31498642 DOI: 10.1021/Acs.Orglett.9B02713 |
0.778 |
|
| 2019 |
Liu J, Liu Y, Liu Y, Huang L, Wang G, Wang J, Xu X, Shi C, Huang J. Anticancer Action of Psilostachyin-A in 5-Fluorouracil-Resistant Human Liver Carcinoma are Mediated Through Autophagy Induction, G2/M Phase Cell Cycle Arrest and Inhibiting Extracellular-Signal-Regulated Kinase/Mitogen Activated Protein Kinase (ERK/MAPK) Signaling Pathway. Medical Science Monitor : International Medical Journal of Experimental and Clinical Research. 25: 6711-6718. PMID 31492830 DOI: 10.12659/MSM.916635 |
0.305 |
|
| 2019 |
Liu J, Liu F, Bao R, Jiang K, Khan F, Li Z, Peng H, Chen J, Alodhayb A, Thundat T. Scaled-up direct-current generation in MoS multilayers-based moving heterojunctions. Acs Applied Materials & Interfaces. PMID 31476860 DOI: 10.1021/acsami.9b09851 |
0.407 |
|
| 2019 |
Kim IS, Gao Y, Welte T, Wang H, Liu J, Janghorban M, Sheng K, Niu Y, Goldstein A, Zhao N, Bado I, Lo HC, Toneff MJ, Nguyen T, Bu W, et al. Immuno-subtyping of breast cancer reveals distinct myeloid cell profiles and immunotherapy resistance mechanisms. Nature Cell Biology. PMID 31451770 DOI: 10.1038/S41556-019-0373-7 |
0.342 |
|
| 2019 |
Lee J, Kosowicz JG, Hayward SD, Desai P, Stone J, Lee JM, Liu JO, Ambinder RF. Pharmacologic Activation of Lytic Epstein-Barr Virus Gene Expression Without Virion Production. Journal of Virology. PMID 31341058 DOI: 10.1128/Jvi.00998-19 |
0.365 |
|
| 2019 |
Liu S, Fu H, Jiang J, Chen Z, Gao J, Shu H, Zhang S, Yang C, Liu J. Overexpression of a CPYC-Type Glutaredoxin, , Causes Abnormal Embryos and an Increased Grain Weight in Rice. Frontiers in Plant Science. 10: 848. PMID 31316541 DOI: 10.3389/fpls.2019.00848 |
0.414 |
|
| 2019 |
Chen BX, Peng YX, Gao JD, Zhang Q, Liu QJ, Fu H, Liu J. Coumarin-Induced Delay of Rice Seed Germination Is Mediated by Suppression of Abscisic Acid Catabolism and Reactive Oxygen Species Production. Frontiers in Plant Science. 10: 828. PMID 31316534 DOI: 10.3389/fpls.2019.00828 |
0.431 |
|
| 2019 |
Zhao ZY, Xie XJ, Li WH, Liu J, Chen Z, Zhang B, Li T, Li SL, Lu JG, Zhang L, Zhang LH, Xu Z, Lee HC, Zhao YJ. A Cell-Permeant Mimetic of NMN Activates SARM1 to Produce Cyclic ADP-Ribose and Induce Non-apoptotic Cell Death. Iscience. 15: 452-466. PMID 31128467 DOI: 10.1016/J.Isci.2019.05.001 |
0.394 |
|
| 2019 |
Li Y, Zhang X, Yang X, Liu J, Li L, Ma W, Chen M. Differential effects of ginkgol C17:1 on cisplatin-induced cytotoxicity: Protecting human normal L02 hepatocytes versus sensitizing human hepatoma HepG2 cells. Oncology Letters. 17: 3181-3190. PMID 30867748 DOI: 10.3892/ol.2019.9974 |
0.307 |
|
| 2019 |
Peiffer BJ, Qi L, Ahmadi AR, Wang Y, Guo Z, Peng H, Sun Z, Liu JO. Activation of BMP Signaling by FKBP12 Ligands Synergizes with Inhibition of CXCR4 to Accelerate Wound Healing. Cell Chemical Biology. PMID 30827938 DOI: 10.1016/J.Chembiol.2019.01.011 |
0.788 |
|
| 2018 |
Guo Z, Hong SY, Wang J, Rehan S, Liu W, Peng H, Das M, Li W, Bhat S, Peiffer B, Ullman BR, Tse CM, Tarmakova Z, Schiene-Fischer C, Fischer G, ... ... Liu JO, et al. Rapamycin-inspired macrocycles with new target specificity. Nature Chemistry. PMID 30532015 DOI: 10.1038/S41557-018-0187-4 |
0.801 |
|
| 2018 |
Yuan L, Liu J, He W, Bao Y, Sheng L, Zou C, Hu B, Ge W, Liu Y, Wang J, Lin B, Li Y, Ma E. Discovery of a novel cathepsin inhibitor with dual autophagy-inducing and metastasis-inhibiting effects on breast cancer cells. Bioorganic Chemistry. 84: 239-253. PMID 30503850 DOI: 10.1016/j.bioorg.2018.11.025 |
0.321 |
|
| 2018 |
Li Y, Pasunooti KK, Li RJ, Liu W, Head SA, Shi WQ, Liu JO. Novel Tetrazole-containing Analogs of Itraconazole as Potent Anti-angiogenic Agents with Reduced CYP3A4 Inhibition. Journal of Medicinal Chemistry. PMID 30481027 DOI: 10.1021/Acs.Jmedchem.8B01252 |
0.826 |
|
| 2018 |
Li D, Liu J, Wang X, Kong D, Du W, Li H, Hse CY, Shupe T, Zhou D, Zhao K. Biological Potential and Mechanism of Prodigiosin from Subsp. in Human Choriocarcinoma and Prostate Cancer Cell Lines. International Journal of Molecular Sciences. 19. PMID 30400387 DOI: 10.3390/ijms19113465 |
0.313 |
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| 2018 |
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Yuan L, Sheng L, He W, Zou C, Hu B, Liu J, Ge W, Liu Y, Wang J, Ma E. Discovery of novel cathepsin inhibitors with potent anti-metastatic effects in breast cancer cells. Bioorganic Chemistry. 81: 672-680. PMID 30253340 DOI: 10.1016/j.bioorg.2018.09.029 |
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Lyu J, Yang EJ, Head SA, Ai N, Zhang B, Wu C, Li RJ, Liu Y, Chakravarty H, Zhang S, Tam KY, Dang Y, Kwon HJ, Ge W, Liu JO, et al. Astemizole Inhibits mTOR Signaling and Angiogenesis by Blocking Cholesterol Trafficking. International Journal of Biological Sciences. 14: 1175-1185. PMID 30123067 DOI: 10.7150/Ijbs.26011 |
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Pan T, Peng Z, Tan L, Zou F, Zhou N, Liu B, Liang L, Chen C, Liu J, Wu L, Liu G, Peng Z, Liu W, Ma X, Zhang J, et al. Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) Potently Inhibit the Replication of Zika Viruses by Inducing the Degradation of AXL. Journal of Virology. PMID 30068645 DOI: 10.1128/JVI.01018-18 |
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Liu X, Sun Z, Li D, Deng J, Liu J, Ma K, Qin S, Si Y, Zhang T, Feng T, Liu Y, Tan Y. Polyphyllin I inhibits invasion and epithelial-mesenchymal transition via CIP2A/PP2A/ERK signaling in prostate cancer. International Journal of Oncology. PMID 29956727 DOI: 10.3892/ijo.2018.4464 |
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Bauer L, Ferla S, Head SA, Bhat S, Pasunooti KK, Shi WQ, Albulescu L, Liu JO, Brancale A, van Kuppeveld FJM, Strating JRPM. Structure-activity relationship study of itraconazole, a broad-range inhibitor of picornavirus replication that targets oxysterol-binding protein (OSBP). Antiviral Research. PMID 29807040 DOI: 10.1016/J.Antiviral.2018.05.010 |
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Yan S, Huang W, Gao J, Fu H, Liu J. Comparative metabolomic analysis of seed metabolites associated with seed storability in rice (Oryza sativa L.) during natural aging. Plant Physiology and Biochemistry : Ppb. 127: 590-598. PMID 29729608 DOI: 10.1016/j.plaphy.2018.04.020 |
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Lam C, Ferguson ID, Mariano MC, Lin YT, Murnane M, Liu H, Smith GA, Wong SW, Taunton J, Liu JO, Mitsiades CS, Hann BC, Aftab BT, Wiita AP. Repurposing tofacitinib as an anti-myeloma therapeutic to reverse growth-promoting effects of the bone marrow microenvironment. Haematologica. PMID 29622655 DOI: 10.3324/Haematol.2017.174482 |
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Cui CY, Liu J, Zheng HB, Jin XY, Zhao XY, Chang WQ, Sun B, Lou HX. Diversity-oriented synthesis of pyrazoles derivatives from flavones and isoflavones leads to the discovery of promising reversal agents of fluconazole resistance in Candida albicans. Bioorganic & Medicinal Chemistry Letters. PMID 29606575 DOI: 10.1016/j.bmcl.2018.03.066 |
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Zheng CJ, Yang LL, Liu J, Zhong L. JTC-801 exerts anti-proliferative effects in human osteosarcoma cells by inducing apoptosis. Journal of Receptor and Signal Transduction Research. 1-8. PMID 29447541 DOI: 10.1080/10799893.2018.1436561 |
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Young DJ, Liu JO, Small D. Combinatorial Approaches to Overcome Plasma Protein Inhibition of FLT3 Tyrosine Kinase Inhibitors Blood. 132: 1362-1362. DOI: 10.1182/Blood-2018-99-118820 |
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Zhang X, Saarinen AM, Hitosugi T, Wang Z, Wang L, Ho TH, Liu J. Inhibition of intracellular lipolysis promotes human cancer cell adaptation to hypoxia. Elife. 6. PMID 29256392 DOI: 10.7554/eLife.31132 |
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Li Z, Cheng Z, Raghothama C, Cui Z, Liu K, Li X, Jiang C, Jiang W, Tan M, Ni X, Pandey A, Liu JO, Dang Y. USP9X controls translation efficiency via deubiquitination of eukaryotic translation initiation factor 4A1. Nucleic Acids Research. PMID 29228324 DOI: 10.1093/Nar/Gkx1226 |
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Zhao L, Liu J, He C, Yan R, Zhou K, Cui Q, Meng X, Li X, Zhang Y, Nie Y, Zhang Y, Hu R, Liu Y, Zhao L, Chen M, et al. Protein kinase A determines platelet life span and survival by regulating apoptosis. The Journal of Clinical Investigation. PMID 29083324 DOI: 10.1172/Jci95109 |
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Lyu J, Yang EJ, Head SA, Ai N, Zhang B, Wu C, Li RJ, Liu Y, Yang C, Dang Y, Kwon HJ, Ge W, Liu JO, Shim JS. Pharmacological blockade of cholesterol trafficking by cepharanthine in endothelial cells suppresses angiogenesis and tumor growth. Cancer Letters. PMID 28923401 DOI: 10.1016/J.Canlet.2017.09.009 |
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Pan W, Zhu S, Qu K, Meeth K, Cheng J, He K, Ma H, Liao Y, Wen X, Roden C, Tobiasova Z, Wei Z, Zhao J, Liu J, Zheng J, et al. The DNA Methylcytosine Dioxygenase Tet2 Sustains Immunosuppressive Function of Tumor-Infiltrating Myeloid Cells to Promote Melanoma Progression. Immunity. 47: 284-297.e5. PMID 28813659 DOI: 10.1016/J.Immuni.2017.07.020 |
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Li Y, Liu J, Yang X, Dong Y, Liu Y, Chen M. Ginkgol C17:1 inhibits tumor growth by blunting the EGF- PI3K/Akt signaling pathway. Journal of Biomedical Research. 31: 232-239. PMID 28808215 DOI: 10.7555/JBR.31.20160039 |
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Liu J, Sun B, Zhao X, Xing J, Gao Y, Chang W, Ji J, Zheng H, Cui C, Ji A, Lou HX. Discovery of Potent Orally Active Protease-Activated Receptor 1 (PAR1) Antagonists Based on Andrographolide. Journal of Medicinal Chemistry. PMID 28745507 DOI: 10.1021/acs.jmedchem.7b00951 |
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Liu Q, Chen K, Liu Z, Huang Y, Zhao R, Wei L, Yu X, He J, Liu J, Qi J, Qin Y, Li B. BORIS up-regulates OCT4 via histone methylation to promote cancer stem cell-like properties in human liver cancer cells. Cancer Letters. PMID 28645561 DOI: 10.1016/j.canlet.2017.06.017 |
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Sun B, Liu J, Gao Y, Zheng HB, Li L, Hu QW, Yuan HQ, Lou HX. Design, synthesis and biological evaluation of nitrogen-containing macrocyclic bisbibenzyl derivatives as potent anticancer agents by targeting the lysosome. European Journal of Medicinal Chemistry. 136: 603-618. PMID 28570977 DOI: 10.1016/j.ejmech.2017.05.050 |
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Kosowicz JG, Lee J, Peiffer B, Guo Z, Chen J, Liao G, Hayward SD, Liu JO, Ambinder RF. Drug modulators of B cell signaling pathways and Epstein-Barr virus lytic activation. Journal of Virology. PMID 28566383 DOI: 10.1128/Jvi.00747-17 |
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Li Q, Zhu Y, Liu J, Yu X, Chen M, Dong N, Gong Y, Yuan Y. HpSlyD inducing CDX2 and VIL1 expression mediated through TCTP protein may contribute to intestinal metaplasia in the stomach. Scientific Reports. 7: 2278. PMID 28536478 DOI: 10.1038/s41598-017-02642-y |
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McClary B, Zinshteyn B, Meyer M, Jouanneau M, Pellegrino S, Yusupova G, Schuller A, Reyes JCP, Lu J, Guo Z, Ayinde S, Luo C, Dang Y, Romo D, Yusupov M, ... ... Liu JO, et al. Inhibition of Eukaryotic Translation by the Antitumor Natural Product Agelastatin A. Cell Chemical Biology. PMID 28457705 DOI: 10.1016/J.Chembiol.2017.04.006 |
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Shi Z, Zhou H, Lu L, Li X, Fu Z, Liu J, Kang Y, Wei Z, Pan B, Liu L, Kong X, Feng S. The roles of microRNAs in spinal cord injury. The International Journal of Neuroscience. 1-43. PMID 28436759 DOI: 10.1080/00207454.2017.1323208 |
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Lu L, Zhou H, Pan B, Li X, Fu Z, Liu J, Shi Z, Chu T, Wei Z, Ning G, Feng S. c-Jun Amino-Terminal Kinase is Involved in Valproic Acid-Mediated Neuronal Differentiation of Mouse Embryonic NSCs and Neurite Outgrowth of NSC-Derived Neurons. Neurochemical Research. PMID 28321599 DOI: 10.1007/s11064-016-2167-7 |
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Vuckovic S, Vandyke K, Rickards DA, McCauley Winter P, Brown SH, Mitchell TW, Liu J, Lu J, Askenase PW, Yuriev E, Capuano B, Ramsland PA, Hill GR, Zannettino AC, Hutchinson AT. The cationic small molecule GW4869 is cytotoxic to high phosphatidylserine-expressing myeloma cells. British Journal of Haematology. PMID 28211573 DOI: 10.1111/Bjh.14561 |
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Head SA, Shi WQ, Yang EJ, Nacev BA, Hong SY, Pasunooti KK, Li RJ, Shim JS, Liu JO. Simultaneous Targeting of NPC1 and VDAC1 by Itraconazole Leads to Synergistic Inhibition of mTOR Signaling and Angiogenesis. Acs Chemical Biology. 12: 174-182. PMID 28103683 DOI: 10.1021/Acschembio.6B00849 |
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John SF, Aniemeke E, Ha NP, Chong CR, Gu P, Zhou J, Zhang Y, Graviss EA, Liu JO, Olaleye OA. Characterization of 2-hydroxy-1-naphthaldehyde isonicotinoyl hydrazone as a novel inhibitor of methionine aminopeptidases from Mycobacterium tuberculosis. Tuberculosis (Edinburgh, Scotland). PMID 27856197 DOI: 10.1016/J.Tube.2016.09.025 |
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Li RJ, Xu J, Fu C, Zhang J, Zheng YG, Jia H, Liu JO. Regulation of mTORC1 by lysosomal calcium and calmodulin. Elife. 5. PMID 27787197 DOI: 10.7554/Elife.19360 |
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Cho YS, Yen CN, Shim JS, Kang DH, Kang SW, Liu JO, Kwon HJ. Antidepressant indatraline induces autophagy and inhibits restenosis via suppression of mTOR/S6 kinase signaling pathway. Scientific Reports. 6: 34655. PMID 27694974 DOI: 10.1038/Srep34655 |
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Head SA, Liu JO. Identification of Small Molecule-binding Proteins in a Native Cellular Environment by Live-cell Photoaffinity Labeling. Journal of Visualized Experiments : Jove. PMID 27684515 DOI: 10.3791/54529 |
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Song Z, Chen CP, Liu J, Wen X, Sun H, Yuan H. Design, synthesis, and biological evaluation of (2E)-(2-oxo-1, 2-dihydro-3H-indol-3-ylidene)acetate derivatives as anti-proliferative agents through ROS-induced cell apoptosis. European Journal of Medicinal Chemistry. 124: 809-819. PMID 27643639 DOI: 10.1016/j.ejmech.2016.09.005 |
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Qiu H, Qian S, Head SA, Liu JO, Jin Z. Insights into the structure-activity relationship of the anticancer compound ZJ-101, a derivative of marine natural product superstolide A: A role played by the lactone moiety. Bioorganic & Medicinal Chemistry Letters. PMID 27595422 DOI: 10.1016/J.Bmcl.2016.08.046 |
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He QL, Minn I, Wang Q, Xu P, Head SA, Datan E, Yu B, Pomper MG, Liu JO. Targeted Delivery and Sustained Antitumor Activity of Triptolide through Glucose Conjugation. Angewandte Chemie (International Ed. in English). PMID 27574181 DOI: 10.1002/Anie.201606121 |
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Xiao S, Yang Z, Qiu X, Lv R, Liu J, Wu M, Liao Y, Liu Q. miR-29c contribute to glioma cells temozolomide sensitivity by targeting O6-methylguanine-DNA methyltransferases indirectely. Oncotarget. PMID 27384876 DOI: 10.18632/oncotarget.10357 |
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Qian S, Shah AK, Head SA, Liu JO, Jin Z. Insights into the structure-activity relationship of the anticancer compound ZJ-101, a derivative of marine natural product superstolide A: A critical role played by the conjugated trienyl lactone moiety. Bioorganic & Medicinal Chemistry Letters. PMID 27374243 DOI: 10.1016/J.Bmcl.2016.06.057 |
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Shah AK, Qian S, Zhang D, Head SA, Liu JO, Jin Z. Insights into the structure-activity relationship of the anticancer compound ZJ-101: A critical role played by the cyclohexene ring. Bioorganic & Medicinal Chemistry Letters. PMID 27133592 DOI: 10.1016/J.Bmcl.2016.04.044 |
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Romo D, Liu JO. Editorial: Strategies for cellular target identification of natural products. Natural Product Reports. PMID 27118358 DOI: 10.1039/c6np90016j |
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Wang J, Wen X, Liu J, Sun H. Mitochondrial biogenesis Inhibitors for Anticancer Therapy: A Review of Recent Patents. Recent Patents On Anti-Cancer Drug Discovery. PMID 27086599 DOI: 10.2174/1574892811666160418123628 |
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Song J, Wang X, Zhu J, Liu J. Rapamycin causes growth arrest and inhibition of invasion in human chondrosarcoma cells. Journal of B.U.On. : Official Journal of the Balkan Union of Oncology. 21: 244-51. PMID 27061554 |
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Zhang Y, Zheng Y, Faheem A, Sun T, Li C, Li Z, Zhao D, Wu C, Liu J. A novel AKT inhibitor, AZD5363, inhibits phosphorylation of AKT downstream molecules, and activates phosphorylation of mTOR and SMG-1 dependent on the liver cancer cell type. Oncology Letters. 11: 1685-1692. PMID 26998062 DOI: 10.3892/ol.2016.4111 |
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Jouanneau M, McClary B, Reyes JC, Chen R, Chen Y, Plunkett W, Cheng X, Milinichik AZ, Albone EF, Liu JO, Romo D. Derivatization of agelastatin A leading to bioactive analogs and a trifunctional probe. Bioorganic & Medicinal Chemistry Letters. PMID 26951751 DOI: 10.1016/J.Bmcl.2016.02.051 |
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Gao J, Fu H, Zhou X, Chen Z, Luo Y, Cui B, Chen G, Liu J. Comparative proteomic analysis of seed embryo proteins associated with seed storability in rice (Oryza sativa L) during natural aging. Plant Physiology and Biochemistry : Ppb / Societe Francaise De Physiologie Vegetale. 103: 31-44. PMID 26950923 DOI: 10.1016/j.plaphy.2016.02.026 |
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Zhou Y, Liu J, Zheng M, Zheng S, Jiang C, Zhou X, Zhang D, Zhao J, Ye D, Zheng M, Jiang H, Liu D, Cheng J, Liu H. Structural optimization and biological evaluation of 1,5-disubstituted pyrazole-3-carboxamines as potent inhibitors of human 5-lipoxygenase. Acta Pharmaceutica Sinica. B. 6: 32-45. PMID 26904397 DOI: 10.1016/j.apsb.2015.11.004 |
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Shim JS, Li RJ, Bumpus N, Head S, Pasunooti K, Yang EJ, Lv J, Shi W, Liu JO. Divergence of Anti-angiogenic Activity and Hepatotoxicity of Different Stereoisomers of Itraconazole. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 26801248 DOI: 10.1158/1078-0432.Ccr-15-1888 |
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Liu J, Zhang L, Ren Y, Gao Y, Kang L, Lu S. Matrine inhibits the expression of adhesion molecules in activated vascular smooth muscle cells. Molecular Medicine Reports. PMID 26783147 DOI: 10.3892/mmr.2016.4767 |
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Fox JM, Moynihan JR, Mott BT, Mazzone JR, Anders NM, Brown PA, Rudek MA, Liu JO, Arav-Boger R, Posner GH, Civin CI, Chen X. Artemisinin-derived dimer ART-838 potently inhibited human acute leukemias, persisted in vivo, and synergized with antileukemic drugs. Oncotarget. PMID 26771236 DOI: 10.18632/Oncotarget.6896 |
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Li R, Xu J, Fu C, Zhang J, Zheng YG, Jia H, Liu JO. Author response: Regulation of mTORC1 by lysosomal calcium and calmodulin Elife. DOI: 10.7554/Elife.19360.017 |
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Head SA, Shi W, Zhao L, Gorshkov K, Pasunooti K, Chen Y, Deng Z, Li RJ, Shim JS, Tan W, Hartung T, Zhang J, Zhao Y, Colombini M, Liu JO. Antifungal drug itraconazole targets VDAC1 to modulate the AMPK/mTOR signaling axis in endothelial cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 26655341 DOI: 10.1073/Pnas.1512867112 |
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Liu J, Guo X, Hu R, Liu X, Wang S, Li S, Li Y, Yang G. Molecular Engineering of Aqueous Soluble Triarylboron-Compound-Based Two-Photon Fluorescent Probe for Mitochondria H2S with Analyte-Induced Finite Aggregation and Excellent Membrane Permeability. Analytical Chemistry. PMID 26634883 DOI: 10.1021/acs.analchem.5b04248 |
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Tang J, Guo H, Zhao M, Yang J, Tsoukalas D, Zhang B, Liu J, Xue C, Zhang W. Highly Stretchable Electrodes on Wrinkled Polydimethylsiloxane Substrates. Scientific Reports. 5: 16527. PMID 26585636 DOI: 10.1038/srep16527 |
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Lu J, Jiang C, Li X, Jiang L, Li Z, Schneider-Poetsch T, Liu J, Yu K, Liu JO, Jiang H, Luo C, Dang Y. A gating mechanism for Pi release governs the mRNA unwinding by eIF4AI during translation initiation. Nucleic Acids Research. PMID 26464436 DOI: 10.1093/Nar/Gkv1033 |
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Lee HG, Kim H, Kim EJ, Park PG, Dong SM, Choi TH, Kim H, Chong CR, Liu JO, Chen J, Ambinder RF, Hayward SD, Park JH, Lee JM. Targeted therapy for Epstein-Barr virus-associated gastric carcinoma using low-dose gemcitabine-induced lytic activation. Oncotarget. PMID 26427042 DOI: 10.18632/Oncotarget.5041 |
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Su XY, Lau JT, Mak WW, Choi KC, Feng TJ, Chen X, Liu CL, Liu J, Liu D, Chen L, Song JM, Zhang Y, Zhao GL, Zhu ZP, Cheng JQ. A preliminary validation of the Brief COPE instrument for assessing coping strategies among people living with HIV in China. Infectious Diseases of Poverty. 4: 41. PMID 26370135 DOI: 10.1186/S40249-015-0074-9 |
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Wang G, Rajpurohit SK, Delaspre F, Walker SL, White DT, Ceasrine A, Kuruvilla R, Li RJ, Shim JS, Liu JO, Parsons MJ, Mumm JS. First quantitative high-throughput screen in zebrafish identifies novel pathways for increasing pancreatic β-cell mass. Elife. 4. PMID 26218223 DOI: 10.7554/Elife.08261 |
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He R, Yu ZH, Zhang RY, Wu L, Gunawan AM, Lane BS, Shim JS, Zeng LF, He Y, Chen L, Wells CD, Liu JO, Zhang ZY. Exploring the Existing Drug Space for Novel pTyr Mimetic and SHP2 Inhibitors. Acs Medicinal Chemistry Letters. 6: 782-6. PMID 26191366 DOI: 10.1021/Acsmedchemlett.5B00118 |
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Liu J, Zhang K, Mai X, Wei J, Liao Y, Zhong Y, Liu Y, Feng L, Liu C. Synthesis, Anticancer Evaluation and Docking Study of 3-Benzyloxyhydantoin Derivatives. Medicinal Chemistry (Shariqah (United Arab Emirates)). PMID 26152144 DOI: 10.2174/1573406411666150708111631 |
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Liu H, Lei C, Long K, Yang X, Zhu Z, Zhang L, Liu J. Mutant GNAQ promotes cell viability and migration of uveal melanoma cells through the activation of Notch signaling. Oncology Reports. 34: 295-301. PMID 25955651 DOI: 10.3892/or.2015.3949 |
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Shim JS, Li RJ, Lv J, Head SA, Yang EJ, Liu JO. Inhibition of angiogenesis by selective estrogen receptor modulators through blockade of cholesterol trafficking rather than estrogen receptor antagonism. Cancer Letters. 362: 106-15. PMID 25799952 DOI: 10.1016/J.Canlet.2015.03.022 |
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Zhu Y, Chen M, Gong Y, Liu Z, Li A, Kang D, Han F, Liu J, Liu J, Yuan Y. Helicobacter pylori FKBP-type PPIase promotes gastric epithelial cell proliferation and anchorage-independent growth through activation of ERK-mediated mitogenic signaling pathway. Fems Microbiology Letters. 362. PMID 25687921 DOI: 10.1093/femsle/fnv023 |
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Saiyin H, Ardito-Abraham CM, Wu Y, Wei Y, Fang Y, Han X, Li J, Zhou P, Yi Q, Maitra A, Liu JO, Tuveson DA, Lou W, Yu L. Identification of novel vascular projections with cellular trafficking abilities on the microvasculature of pancreatic ductal adenocarcinoma. The Journal of Pathology. 236: 142-54. PMID 25561062 DOI: 10.1002/Path.4506 |
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He QL, Titov DV, Li J, Tan M, Ye Z, Zhao Y, Romo D, Liu JO. Covalent modification of a cysteine residue in the XPB subunit of the general transcription factor TFIIH through single epoxide cleavage of the transcription inhibitor triptolide. Angewandte Chemie (International Ed. in English). 54: 1859-63. PMID 25504624 DOI: 10.1002/Anie.201408817 |
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Murnane M, Dhimolea E, Li R, Bariteau MA, Wheeler DD, Akhurst RJ, Logan AC, Munster P, Wiita A, Martin TG, Wolf JL, Liu JO, Mitsiades CS, Aftab BT. Defining Primary Marrow Microenvironment-Induced Synthetic Lethality and Resistance for 2,684 Approved Drugs Across Molecularly Distinct Forms of Multiple Myeloma Blood. 126: 503-503. DOI: 10.1182/Blood.V126.23.503.503 |
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Zhang W, Lv S, Liu J, Zang Z, Yin J, An N, Yang H, Song Y. PCI-24781 down-regulates EZH2 expression and then promotes glioma apoptosis by suppressing the PIK3K/Akt/mTOR pathway. Genetics and Molecular Biology. 37: 716-24. PMID 25505847 DOI: 10.1590/S1415-47572014005000011 |
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Cai Y, Tan X, Liu J, Shen Y, Wu D, Ren M, Huang P, Yu D. Inhibition of PI3K/Akt/mTOR signaling pathway enhances the sensitivity of the SKOV3/DDP ovarian cancer cell line to cisplatin in vitro. Chinese Journal of Cancer Research = Chung-Kuo Yen Cheng Yen Chiu. 26: 564-72. PMID 25400422 DOI: 10.3978/j.issn.1000-9604.2014.08.20 |
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Tong SJ, Liu J, Wang X, Qu LX. microRNA-181 promotes prostate cancer cell proliferation by regulating DAX-1 expression. Experimental and Therapeutic Medicine. 8: 1296-1300. PMID 25187843 DOI: 10.3892/etm.2014.1846 |
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Liu J, Tong SJ, Wang X, Qu LX. Farnesoid X receptor inhibits LNcaP cell proliferation via the upregulation of PTEN. Experimental and Therapeutic Medicine. 8: 1209-1212. PMID 25187826 DOI: 10.3892/etm.2014.1894 |
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Wu J, Feng X, Zhang B, Li J, Xu X, Liu J, Wang X, Wang J, Tong X. Blocking the bFGF/STAT3 interaction through specific signaling pathways induces apoptosis in glioblastoma cells. Journal of Neuro-Oncology. 120: 33-41. PMID 25048528 DOI: 10.1007/s11060-014-1529-8 |
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Shim JS, Liu JO. Recent advances in drug repositioning for the discovery of new anticancer drugs. International Journal of Biological Sciences. 10: 654-63. PMID 25013375 DOI: 10.7150/Ijbs.9224 |
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| 2014 |
Wang M, Shim JS, Li RJ, Dang Y, He Q, Das M, Liu JO. Identification of an old antibiotic clofoctol as a novel activator of unfolded protein response pathways and an inhibitor of prostate cancer. British Journal of Pharmacology. 171: 4478-89. PMID 24903412 DOI: 10.1111/Bph.12800 |
0.801 |
|
| 2014 |
Wissing MD, Dadon T, Kim E, Piontek KB, Shim JS, Kaelber NS, Liu JO, Kachhap SK, Nelkin BD. Small-molecule screening of PC3 prostate cancer cells identifies tilorone dihydrochloride to selectively inhibit cell growth based on cyclin-dependent kinase 5 expression. Oncology Reports. 32: 419-24. PMID 24841903 DOI: 10.3892/Or.2014.3174 |
0.62 |
|
| 2014 |
Sun L, Zhang Y, Zhao B, Deng M, Liu J, Li X, Hou J, Gui M, Zhang S, Li X, Gao GF, Meng S. A new unconventional HLA-A2-restricted epitope from HBV core protein elicits antiviral cytotoxic T lymphocytes. Protein & Cell. 5: 317-27. PMID 24659387 DOI: 10.1007/s13238-014-0041-4 |
0.331 |
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| 2014 |
Jing X, Shi Q, Bi W, Zeng Z, Liang Y, Wu X, Xiao S, Liu J, Yang L, Tao E. Rifampicin protects PC12 cells from rotenone-induced cytotoxicity by activating GRP78 via PERK-eIF2α-ATF4 pathway. Plos One. 9: e92110. PMID 24638036 DOI: 10.1371/journal.pone.0092110 |
0.312 |
|
| 2014 |
Dong J, Gong Y, Liu J, Chen X, Wen X, Sun H. Synthesis and biological evaluation of all eight stereoisomers of DPP-IV inhibitor saxagliptin. Bioorganic & Medicinal Chemistry. 22: 1383-93. PMID 24457090 DOI: 10.1016/j.bmc.2013.12.061 |
0.333 |
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| 2014 |
Low WK, Li J, Zhu M, Kommaraju SS, Shah-Mittal J, Hull K, Liu JO, Romo D. Second-generation derivatives of the eukaryotic translation initiation inhibitor pateamine A targeting eIF4A as potential anticancer agents. Bioorganic & Medicinal Chemistry. 22: 116-25. PMID 24359706 DOI: 10.1016/J.Bmc.2013.11.046 |
0.627 |
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| 2014 |
Wu J, Liu J, Jia R, Song H. Nur77 inhibits androgen-induced bladder cancer growth. Cancer Investigation. 31: 654-60. PMID 24299210 DOI: 10.3109/07357907.2013.853077 |
0.317 |
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| 2014 |
Heckmann BL, Yang X, Zhang X, Liu J. The autophagic inhibitor 3-methyladenine potently stimulates PKA-dependent lipolysis in adipocytes. British Journal of Pharmacology. 168: 163-71. PMID 22817685 DOI: 10.1111/j.1476-5381.2012.02110.x |
0.326 |
|
| 2014 |
Chalugun P, Shim JS, Korangath PC, Sukumar S, Liu JO. Abstract 443: Synergistic inhibition of HER2 positive breast cancer by triptolide and lapatinib Cancer Research. 74: 443-443. DOI: 10.1158/1538-7445.Am2014-443 |
0.577 |
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| 2014 |
Chalugun P, Shim J, Korangath P, Sukumar S, Liu J. 98 Synergistic inhibition of HER2 positive breast cancer by triptolide and lapatinib European Journal of Cancer. 50: 36. DOI: 10.1016/S0959-8049(14)70224-2 |
0.487 |
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| 2013 |
Liu J, Pan S, Hsieh MH, Ng N, Sun F, Wang T, Kasibhatla S, Schuller AG, Li AG, Cheng D, Li J, Tompkins C, Pferdekamper A, Steffy A, Cheng J, et al. Targeting Wnt-driven cancer through the inhibition of Porcupine by LGK974. Proceedings of the National Academy of Sciences of the United States of America. 110: 20224-9. PMID 24277854 DOI: 10.1073/Pnas.1314239110 |
0.492 |
|
| 2013 |
Ding G, Feng C, Jiang H, Ding Q, Zhang L, Na R, Xu H, Liu J. Combination of rapamycin, CI-1040, and 17-AAG inhibits metastatic capacity of prostate cancer via Slug inhibition. Plos One. 8: e77400. PMID 24130883 DOI: 10.1371/journal.pone.0077400 |
0.343 |
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| 2013 |
Yang M, Li SN, Anjum KM, Gui LX, Zhu SS, Liu J, Chen JK, Liu QF, Ye GD, Wang WJ, Wu JF, Cai WY, Sun GB, Liu YJ, Liu RF, et al. A double-negative feedback loop between Wnt-β-catenin signaling and HNF4α regulates epithelial-mesenchymal transition in hepatocellular carcinoma. Journal of Cell Science. 126: 5692-703. PMID 24101726 DOI: 10.1242/jcs.135053 |
0.459 |
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| 2013 |
Liu J, Zhang R, Chen F, Yu C, Sun Y, Jia C, Zhang L, Salahuddin T, Li X, Lang J, Song X. MGMT Leu84Phe polymorphism contributes to cancer susceptibility: evidence from 44 case-control studies. Plos One. 8: e75367. PMID 24086516 DOI: 10.1371/journal.pone.0075367 |
0.3 |
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| 2013 |
Kishor C, Arya T, Reddi R, Chen X, Saddanapu V, Marapaka AK, Gumpena R, Ma D, Liu JO, Addlagatta A. Identification, biochemical and structural evaluation of species-specific inhibitors against type I methionine aminopeptidases. Journal of Medicinal Chemistry. 56: 5295-305. PMID 23767698 DOI: 10.1021/Jm400395P |
0.579 |
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| 2013 |
Liu C, Ma H, Wu J, Huang Q, Liu JO, Yu L. Arginine68 is an essential residue for the C-terminal cleavage of human Atg8 family proteins. Bmc Cell Biology. 14: 27. PMID 23721406 DOI: 10.1186/1471-2121-14-27 |
0.344 |
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| 2013 |
Chang BH, Liu X, Liu J, Quan FS, Guo ZK, Zhang Y. Developmental expression and possible functional roles of mouse Nlrp4e in preimplantation embryos. In Vitro Cellular & Developmental Biology. Animal. 49: 548-53. PMID 23708922 DOI: 10.1007/s11626-013-9638-9 |
0.576 |
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| 2013 |
Li G, Diogo D, Wu D, Spoonamore J, Dancik V, Franke L, Kurreeman F, Rossin EJ, Duclos G, Hartland C, Zhou X, Li K, Liu J, De Jager PL, Siminovitch KA, et al. Human genetics in rheumatoid arthritis guides a high-throughput drug screen of the CD40 signaling pathway. Plos Genetics. 9: e1003487. PMID 23696745 DOI: 10.1371/Journal.Pgen.1003487 |
0.544 |
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| 2013 |
Zhang Y, Ren Y, Wu Y, Zhao B, Qiu L, Li X, Xu D, Liu J, Gao GF, Meng S. The L60V variation in hepatitis B virus core protein elicits new epitope-specific cytotoxic T lymphocytes and enhances viral replication. Journal of Virology. 87: 8075-84. PMID 23678186 DOI: 10.1128/JVI.00577-13 |
0.316 |
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| 2013 |
Kong X, Peng B, Yang Y, Zhang P, Qin B, Han D, Wang C, Dang Y, Liu JO, Yu L. p53 Represses transcription of RING finger LIM domain-binding protein RLIM through Sp1. Plos One. 8: e62832. PMID 23650532 DOI: 10.1371/Journal.Pone.0062832 |
0.639 |
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| 2013 |
Zhang F, Bhat S, Gabelli SB, Chen X, Miller MS, Nacev BA, Cheng YL, Meyers DJ, Tenney K, Shim JS, Crews P, Amzel LM, Ma D, Liu JO. Pyridinylquinazolines selectively inhibit human methionine aminopeptidase-1 in cells Journal of Medicinal Chemistry. 56: 3996-4016. PMID 23634668 DOI: 10.1021/Jm400227Z |
0.817 |
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| 2013 |
Fatokun AA, Liu JO, Dawson VL, Dawson TM. Identification through high-throughput screening of 4'-methoxyflavone and 3',4'-dimethoxyflavone as novel neuroprotective inhibitors of parthanatos. British Journal of Pharmacology. 169: 1263-78. PMID 23550801 DOI: 10.1111/Bph.12201 |
0.389 |
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| 2013 |
Rudin CM, Brahmer JR, Juergens RA, Hann CL, Ettinger DS, Sebree R, Smith R, Aftab BT, Huang P, Liu JO. Phase 2 study of pemetrexed and itraconazole as second-line therapy for metastatic nonsquamous non-small-cell lung cancer. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 8: 619-23. PMID 23546045 DOI: 10.1097/Jto.0B013E31828C3950 |
0.359 |
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| 2013 |
Bhat S, Shim JS, Liu JO. Tricyclic thiazoles are a new class of angiogenesis inhibitors. Bioorganic & Medicinal Chemistry Letters. 23: 2733-7. PMID 23518276 DOI: 10.1016/J.Bmcl.2013.02.067 |
0.796 |
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| 2013 |
Zhang P, Yang X, Zhang F, Gabelli SB, Wang R, Zhang Y, Bhat S, Chen X, Furlani M, Amzel LM, Liu JO, Ma D. Pyridinylpyrimidines selectively inhibit human methionine aminopeptidase-1. Bioorganic & Medicinal Chemistry. 21: 2600-17. PMID 23507151 DOI: 10.1016/J.Bmc.2013.02.023 |
0.825 |
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| 2013 |
Liu X, Lin Y, Liu J, Song B, Ou Y, Zhang H, Li M, Xie C. StInvInh2 as an inhibitor of StvacINV1 regulates the cold-induced sweetening of potato tubers by specifically capping vacuolar invertase activity. Plant Biotechnology Journal. 11: 640-7. PMID 23421503 DOI: 10.1111/pbi.12054 |
0.309 |
|
| 2013 |
Wissing MD, Mendonca J, Kim E, Kim E, Shim JS, Kaelber NS, Kant H, Hammers H, Commes T, Van Diest PJ, Liu JO, Kachhap SK. Identification of cetrimonium bromide and irinotecan as compounds with synthetic lethality against NDRG1 deficient prostate cancer cells. Cancer Biology & Therapy. 14: 401-10. PMID 23377825 DOI: 10.4161/Cbt.23759 |
0.611 |
|
| 2013 |
Kamiyama H, Rauenzahn S, Shim JS, Karikari CA, Feldmann G, Hua L, Kamiyama M, Schuler FW, Lin MT, Beaty RM, Karanam B, Liang H, Mullendore ME, Mo G, Hidalgo M, ... ... Liu JO, et al. Personalized chemotherapy profiling using cancer cell lines from selectable mice. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 19: 1139-46. PMID 23340293 DOI: 10.1158/1078-0432.Ccr-12-2127 |
0.577 |
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| 2013 |
Choi SM, Kim Y, Shim JS, Park JT, Wang RH, Leach SD, Liu JO, Deng C, Ye Z, Jang YY. Efficient drug screening and gene correction for treating liver disease using patient-specific stem cells. Hepatology (Baltimore, Md.). 57: 2458-68. PMID 23325555 DOI: 10.1002/Hep.26237 |
0.614 |
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| 2013 |
Zhang L, Dong J, Zhang Y, Liu J, Zhang L, Sun H. Design, synthesis, and biological evaluation of potent photoaffinity probes of oleanolic acid. Medicinal Chemistry. 9: 294-302. PMID 22931495 DOI: 10.2174/1573406411309020012 |
0.382 |
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| 2013 |
Zhang L, Dong J, Liu J, Zhang L, Kong L, Yao H, Sun H. Synthesis and biological evaluation of novel pentacyclic triterpene derivatives as potential PPARγ agonists. Medicinal Chemistry (Shariqah (United Arab Emirates)). 9: 118-25. PMID 22779802 DOI: 10.2174/157340613804488413 |
0.406 |
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| 2013 |
Xiao Q, Qu K, Wang C, Kong Y, Liu C, Jiang D, Saiyin H, Jia F, Ni C, Chen T, Zhang Y, Zhang P, Qin W, Sun Q, Wang H, ... ... Liu J, et al. HDGF-related protein-3 is required for anchorage-independent survival and chemoresistance in hepatocellular carcinomas Gut. 62: 440-451. PMID 22490522 DOI: 10.1136/Gutjnl-2011-300781 |
0.355 |
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| 2013 |
Kamiyama H, Rauenzahn S, Shim JS, Liu JO, Maitra A, Eshleman JR. Abstract 4155: Personalized chemosensitivity profiling of cancers isolated from genetically-engineered mice. Cancer Research. 73: 4155-4155. DOI: 10.1158/1538-7445.Am2013-4155 |
0.578 |
|
| 2012 |
Jing C, Na R, Wang B, Liu H, Zhang L, Liu J, Wang M, Zhong J, Kwon O, Guo H. Phosphine-Catalyzed [3+2] and [4+3]Annulation Reactions of C,N-Cyclic Azomethine Imines with Allenoates. Advanced Synthesis & Catalysis. 354: 1023-1034. PMID 25525424 DOI: 10.1002/Adsc.201100831 |
0.449 |
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| 2012 |
Zhang L, Chen X, Liu J, Zhu Q, Leng Y, Luo X, Jiang H, Liu H. Discovery of novel dual-action antidiabetic agents that inhibit glycogen phosphorylase and activate glucokinase. European Journal of Medicinal Chemistry. 58: 624-39. PMID 23178962 DOI: 10.1016/j.ejmech.2012.06.020 |
0.308 |
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| 2012 |
Zhou QG, Jiang JP, Wu SJ, Tian JW, Chen JH, Yu XQ, Chen PY, Mei CL, Xiong F, Shi W, Zhou W, Liu XS, Sun SR, Xie D, Liu J, et al. Current pattern of Chinese dialysis units: a cohort study in a representative sample of units. Chinese Medical Journal. 125: 3434-9. PMID 23044302 |
0.451 |
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| 2012 |
Shim JS, Rao R, Beebe K, Neckers L, Han I, Nahta R, Liu JO. Selective inhibition of HER2-positive breast cancer cells by the HIV protease inhibitor nelfinavir. Journal of the National Cancer Institute. 104: 1576-90. PMID 23042933 DOI: 10.1093/Jnci/Djs396 |
0.608 |
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| 2012 |
Hou F, Jiang J, Chen J, Yu X, Zhou Q, Chen P, Mei C, Xiong F, Shi W, Zhou W, Liu X, Sun S, Xie D, Liu J, Zhang P, et al. China collaborative study on dialysis: a multi-centers cohort study on cardiovascular diseases in patients on maintenance dialysis. Bmc Nephrology. 13: 94. PMID 22935444 DOI: 10.1186/1471-2369-13-94 |
0.455 |
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| 2012 |
Miller E, Yang J, DeRan M, Wu C, Su AI, Bonamy GM, Liu J, Peters EC, Wu X. Identification of serum-derived sphingosine-1-phosphate as a small molecule regulator of YAP. Chemistry & Biology. 19: 955-62. PMID 22884261 DOI: 10.1016/J.Chembiol.2012.07.005 |
0.306 |
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| 2012 |
Chen XY, Gu XT, Saiyin H, Wan B, Zhang YJ, Li J, Wang YL, Gao R, Wang YF, Dong WP, Najjar SM, Zhang CY, Ding HF, Liu JO, Yu L. Brain-selective kinase 2 (BRSK2) phosphorylation on PCTAIRE1 negatively regulates glucose-stimulated insulin secretion in pancreatic β-cells. The Journal of Biological Chemistry. 287: 30368-75. PMID 22798068 DOI: 10.1074/Jbc.M112.375618 |
0.351 |
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| 2012 |
Krátký M, Vinšová J, Novotná E, Mandíková J, Wsól V, Trejtnar F, Ulmann V, Stolaříková J, Fernandes S, Bhat S, Liu JO. Salicylanilide derivatives block Mycobacterium tuberculosis through inhibition of isocitrate lyase and methionine aminopeptidase. Tuberculosis (Edinburgh, Scotland). 92: 434-9. PMID 22765970 DOI: 10.1016/J.Tube.2012.06.001 |
0.738 |
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| 2012 |
Zhou Q, Wu S, Jiang J, Tian J, Chen J, Yu X, Chen P, Mei C, Xiong F, Shi W, Zhou W, Liu X, Sun S, Xie DI, Liu J, et al. Accumulation of circulating advanced oxidation protein products is an independent risk factor for ischaemic heart disease in maintenance haemodialysis patients. Nephrology (Carlton, Vic.). 17: 642-9. PMID 22738256 DOI: 10.1111/j.1440-1797.2012.01640.x |
0.47 |
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| 2012 |
Bhat S, Olaleye O, Meyer KJ, Shi W, Zhang Y, Liu JO. Analogs of N'-hydroxy-N-(4H,5H-naphtho[1,2-d]thiazol-2-yl)methanimidamide inhibit Mycobacterium tuberculosis methionine aminopeptidases. Bioorganic & Medicinal Chemistry. 20: 4507-13. PMID 22704656 DOI: 10.1016/J.Bmc.2012.05.022 |
0.804 |
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| 2012 |
Liu-Chittenden Y, Huang B, Shim JS, Chen Q, Lee SJ, Anders RA, Liu JO, Pan D. Genetic and pharmacological disruption of the TEAD-YAP complex suppresses the oncogenic activity of YAP. Genes & Development. 26: 1300-5. PMID 22677547 DOI: 10.1101/Gad.192856.112 |
0.614 |
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| 2012 |
Bhat S, Shim JS, Zhang F, Chong CR, Liu JO. Substituted oxines inhibit endothelial cell proliferation and angiogenesis. Organic & Biomolecular Chemistry. 10: 2979-92. PMID 22391578 DOI: 10.1039/C2Ob06978D |
0.834 |
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| 2012 |
Wang C, An J, Zhang P, Xu C, Gao K, Wu D, Wang D, Yu H, Liu JO, Yu L. The Nedd4-like ubiquitin E3 ligases target angiomotin/p130 to ubiquitin-dependent degradation. The Biochemical Journal. 444: 279-89. PMID 22385262 DOI: 10.1042/Bj20111983 |
0.371 |
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| 2012 |
Shamay M, Liu J, Li R, Liao G, Shen L, Greenway M, Hu S, Zhu J, Xie Z, Ambinder RF, Qian J, Zhu H, Hayward SD. A protein array screen for Kaposi's sarcoma-associated herpesvirus LANA interactors links LANA to TIP60, PP2A activity, and telomere shortening. Journal of Virology. 86: 5179-91. PMID 22379092 DOI: 10.1128/Jvi.00169-12 |
0.334 |
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| 2012 |
Titov DV, Liu JO. Identification and validation of protein targets of bioactive small molecules. Bioorganic & Medicinal Chemistry. 20: 1902-9. PMID 22226983 DOI: 10.1016/J.Bmc.2011.11.070 |
0.637 |
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| 2012 |
Xing S, Bhat S, Shroff NS, Zhang H, Lopez JA, Margolick JB, Liu JO, Siliciano RF. Novel structurally related compounds reactivate latent HIV-1 in a bcl-2-transduced primary CD4+ T cell model without inducing global T cell activation. The Journal of Antimicrobial Chemotherapy. 67: 398-403. PMID 22160146 DOI: 10.1093/Jac/Dkr496 |
0.701 |
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| 2012 |
Peng CC, Shi W, Lutz JD, Kunze KL, Liu JO, Nelson WL, Isoherranen N. Stereospecific metabolism of itraconazole by CYP3A4: dioxolane ring scission of azole antifungals. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 40: 426-35. PMID 22106171 DOI: 10.1124/Dmd.111.042739 |
0.437 |
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| 2012 |
Nacev BA, Grassi P, Dell A, Haslam SM, Liu JO. Abstract 2316: Itraconazole, an antifungal drug with anti-angiogenic activity, inhibits VEGFR2 trafficking, glycosylation, and signaling in endothelial cells Cancer Research. 72: 2316-2316. DOI: 10.1158/1538-7445.Am2012-2316 |
0.756 |
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| 2011 |
Platz EA, Yegnasubramanian S, Liu JO, Chong CR, Shim JS, Kenfield SA, Stampfer MJ, Willett WC, Giovannucci E, Nelson WG. A novel two-stage, transdisciplinary study identifies digoxin as a possible drug for prostate cancer treatment. Cancer Discovery. 1: 68-77. PMID 22140654 DOI: 10.1158/2159-8274.Cd-10-0020 |
0.767 |
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| 2011 |
Olaleye O, Raghunand TR, Bhat S, Chong C, Gu P, Zhou J, Zhang Y, Bishai WR, Liu JO. Characterization of clioquinol and analogues as novel inhibitors of methionine aminopeptidases from Mycobacterium tuberculosis. Tuberculosis (Edinburgh, Scotland). 91: S61-5. PMID 22115541 DOI: 10.1016/J.Tube.2011.10.012 |
0.807 |
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| 2011 |
Rovira M, Huang W, Yusuff S, Shim JS, Ferrante AA, Liu JO, Parsons MJ. Chemical screen identifies FDA-approved drugs and target pathways that induce precocious pancreatic endocrine differentiation. Proceedings of the National Academy of Sciences of the United States of America. 108: 19264-9. PMID 22084084 DOI: 10.1073/Pnas.1113081108 |
0.601 |
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| 2011 |
Nacev BA, Grassi P, Dell A, Haslam SM, Liu JO. The antifungal drug itraconazole inhibits vascular endothelial growth factor receptor 2 (VEGFR2) glycosylation, trafficking, and signaling in endothelial cells. The Journal of Biological Chemistry. 286: 44045-56. PMID 22025615 DOI: 10.1074/Jbc.M111.278754 |
0.761 |
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| 2011 |
Nacev BA, Liu JO. Synergistic inhibition of endothelial cell proliferation, tube formation, and sprouting by cyclosporin A and itraconazole. Plos One. 6: e24793. PMID 21969860 DOI: 10.1371/Journal.Pone.0024793 |
0.769 |
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| 2011 |
Leung E, Datti A, Cossette M, Goodreid J, McCaw SE, Mah M, Nakhamchik A, Ogata K, El Bakkouri M, Cheng YQ, Wodak SJ, Eger BT, Pai EF, Liu J, Gray-Owen S, et al. Activators of cylindrical proteases as antimicrobials: identification and development of small molecule activators of ClpP protease. Chemistry & Biology. 18: 1167-78. PMID 21944755 DOI: 10.1016/J.Chembiol.2011.07.023 |
0.334 |
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| 2011 |
Shi W, Nacev BA, Aftab BT, Head S, Rudin CM, Liu JO. Itraconazole side chain analogues: structure-activity relationship studies for inhibition of endothelial cell proliferation, vascular endothelial growth factor receptor 2 (VEGFR2) glycosylation, and hedgehog signaling. Journal of Medicinal Chemistry. 54: 7363-74. PMID 21936514 DOI: 10.1021/Jm200944B |
0.833 |
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| 2011 |
Liu J, Xu X, Feng X, Zhang B, Wang J. Adenovirus-mediated delivery of bFGF small interfering RNA reduces STAT3 phosphorylation and induces the depolarization of mitochondria and apoptosis in glioma cells U251. Journal of Experimental & Clinical Cancer Research : Cr. 30: 80. PMID 21906308 DOI: 10.1186/1756-9966-30-80 |
0.303 |
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| 2011 |
Aftab BT, Dobromilskaya I, Liu JO, Rudin CM. Itraconazole inhibits angiogenesis and tumor growth in non-small cell lung cancer. Cancer Research. 71: 6764-72. PMID 21896639 DOI: 10.1158/0008-5472.Can-11-0691 |
0.429 |
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| 2011 |
Chamni S, He QL, Dang Y, Bhat S, Liu JO, Romo D. Diazo reagents with small steric footprints for simultaneous arming/SAR studies of alcohol-containing natural products via O-H insertion. Acs Chemical Biology. 6: 1175-81. PMID 21894934 DOI: 10.1021/Cb2002686 |
0.799 |
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| 2011 |
Li W, Bhat S, Liu JO. A simple and efficient route to the FKBP-binding domain from rapamycin. Tetrahedron Letters. 52: 5070-5072. PMID 21894238 DOI: 10.1016/J.Tetlet.2011.07.094 |
0.712 |
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| 2011 |
Liu J, Johnson K, Li J, Piamonte V, Steffy BM, Hsieh MH, Ng N, Zhang J, Walker JR, Ding S, Muneoka K, Wu X, Glynne R, Schultz PG. Regenerative phenotype in mice with a point mutation in transforming growth factor beta type I receptor (TGFBR1). Proceedings of the National Academy of Sciences of the United States of America. 108: 14560-5. PMID 21841138 DOI: 10.1073/Pnas.1111056108 |
0.385 |
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| 2011 |
Dang Y, Schneider-Poetsch T, Eyler DE, Jewett JC, Bhat S, Rawal VH, Green R, Liu JO. Inhibition of eukaryotic translation elongation by the antitumor natural product Mycalamide B. Rna (New York, N.Y.). 17: 1578-88. PMID 21693620 DOI: 10.1261/Rna.2624511 |
0.816 |
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| 2011 |
Nacev BA, Low WK, Huang Z, Su TT, Su Z, Alkuraya H, Kasuga D, Sun W, Träger M, Braun M, Fischer G, Zhang K, Liu JO. A calcineurin-independent mechanism of angiogenesis inhibition by a nonimmunosuppressive cyclosporin A analog. The Journal of Pharmacology and Experimental Therapeutics. 338: 466-75. PMID 21562139 DOI: 10.1124/Jpet.111.180851 |
0.845 |
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| 2011 |
Huang C, Jiang T, Zhu L, Liu J, Cao J, Huang KJ, Qiu ZJ. STAT3-targeting RNA interference inhibits pancreatic cancer angiogenesis in vitro and in vivo. International Journal of Oncology. 38: 1637-44. PMID 21479358 DOI: 10.3892/ijo.2011.1000 |
0.328 |
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| 2011 |
Wilson BA, Wang H, Nacev BA, Mease RC, Liu JO, Pomper MG, Isaacs WB. High-throughput screen identifies novel inhibitors of cancer biomarker α-methylacyl coenzyme A racemase (AMACR/P504S). Molecular Cancer Therapeutics. 10: 825-38. PMID 21441411 DOI: 10.1158/1535-7163.Mct-10-0902 |
0.743 |
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| 2011 |
Titov DV, Gilman B, He QL, Bhat S, Low WK, Dang Y, Smeaton M, Demain AL, Miller PS, Kugel JF, Goodrich JA, Liu JO. XPB, a subunit of TFIIH, is a target of the natural product triptolide. Nature Chemical Biology. 7: 182-8. PMID 21278739 DOI: 10.1038/Nchembio.522 |
0.822 |
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| 2011 |
Liu JO, Titov DV, Dang Y, He Q. Regulator of Ras depalmitoylation and retrograde trafficking: a new hat for FKBP. Molecular Cell. 41: 131-3. PMID 21255722 DOI: 10.1016/J.Molcel.2011.01.009 |
0.765 |
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| 2011 |
Lin J, Haffner MC, Zhang Y, Lee BH, Brennen WN, Britton J, Kachhap SK, Shim JS, Liu JO, Nelson WG, Yegnasubramanian S, Carducci MA. Disulfiram is a DNA demethylating agent and inhibits prostate cancer cell growth. The Prostate. 71: 333-43. PMID 20809552 DOI: 10.1002/Pros.21247 |
0.614 |
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| 2011 |
Aftab BT, Dobromilskaya I, Hann CL, Liu JO, Rudin CM. Abstract 3271: Inhibition of angiogenesis and tumor growth by itraconazole in primary xenograft models of human non-small cell lung cancer Cancer Research. 71: 3271-3271. DOI: 10.1158/1538-7445.Am2011-3271 |
0.344 |
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| 2011 |
Wissing MD, Kim E, Dadon T, Shim JS, Mendonca J, Piontek K, Liu JO, Carducci MA, Kachhap SK, Nelkin BD. Abstract 2976: Small molecule screening of prostate and pancreatic cancer cell lines identifies tilorone dihydrochloride as a compound that selectively inhibits growth in cells with inhibited cyclin-dependent kinase 5 Cancer Research. 71: 2976-2976. DOI: 10.1158/1538-7445.Am2011-2976 |
0.621 |
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| 2011 |
Aftab BT, Shi W, Nacev BA, Head S, Liu JO, Rudin CM. Abstract C147: Itraconazole side-chain analogs reveal a distinct structure-activity relationship for inhibition of hedgehog pathway signaling. Molecular Cancer Therapeutics. 10. DOI: 10.1158/1535-7163.Targ-11-C147 |
0.841 |
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| 2010 |
Pan S, Wu X, Jiang J, Gao W, Wan Y, Cheng D, Han D, Liu J, Englund NP, Wang Y, Peukert S, Miller-Moslin K, Yuan J, Guo R, Matsumoto M, et al. Discovery of NVP-LDE225, a Potent and Selective Smoothened Antagonist. Acs Medicinal Chemistry Letters. 1: 130-4. PMID 24900187 DOI: 10.1021/Ml1000307 |
0.307 |
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| 2010 |
Shi W, Nacev BA, Bhat S, Liu JO. Impact of Absolute Stereochemistry on the Antiangiogenic and Antifungal Activities of Itraconazole. Acs Medicinal Chemistry Letters. 1: 155-159. PMID 21892383 DOI: 10.1021/Ml1000068 |
0.806 |
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| 2010 |
Shim JS, Matsui Y, Bhat S, Nacev BA, Xu J, Bhang HE, Dhara S, Han KC, Chong CR, Pomper MG, So A, Liu JO. Effect of nitroxoline on angiogenesis and growth of human bladder cancer. Journal of the National Cancer Institute. 102: 1855-73. PMID 21088277 DOI: 10.1093/Jnci/Djq457 |
0.815 |
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| 2010 |
Zhu P, Jiang W, Cao L, Yu W, Pei Y, Yang X, Wan B, Liu JO, Yi Q, Yu L. IL-2 mRNA stabilization upon PMA stimulation is dependent on NF90-Ser647 phosphorylation by protein kinase CbetaI. Journal of Immunology (Baltimore, Md. : 1950). 185: 5140-9. PMID 20870937 DOI: 10.4049/Jimmunol.1000849 |
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Huang W, Ding L, Huang Q, Hu H, Liu S, Yang X, Hu X, Dang Y, Shen S, Li J, Ji X, Jiang S, Liu JO, Yu L. Carbonyl reductase 1 as a novel target of (-)-epigallocatechin gallate against hepatocellular carcinoma. Hepatology (Baltimore, Md.). 52: 703-14. PMID 20683966 DOI: 10.1002/Hep.23723 |
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| 2010 |
Liu J, Afroza H, Rader DJ, Jin W. Angiopoietin-like protein 3 inhibits lipoprotein lipase activity through enhancing its cleavage by proprotein convertases. The Journal of Biological Chemistry. 285: 27561-70. PMID 20581395 DOI: 10.1074/Jbc.M110.144279 |
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Xiao Q, Zhang F, Nacev BA, Liu JO, Pei D. Protein N-terminal processing: substrate specificity of Escherichia coli and human methionine aminopeptidases. Biochemistry. 49: 5588-99. PMID 20521764 DOI: 10.1021/Bi1005464 |
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Li W, Dang Y, Liu JO, Yu B. Structural and stereochemical requirements of the spiroketal group of hippuristanol for antiproliferative activity. Bioorganic & Medicinal Chemistry Letters. 20: 3112-5. PMID 20409710 DOI: 10.1016/J.Bmcl.2010.03.093 |
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| 2010 |
Kim J, Tang JY, Gong R, Kim J, Lee JJ, Clemons KV, Chong CR, Chang KS, Fereshteh M, Gardner D, Reya T, Liu JO, Epstein EH, Stevens DA, Beachy PA. Itraconazole, a commonly used antifungal that inhibits Hedgehog pathway activity and cancer growth. Cancer Cell. 17: 388-99. PMID 20385363 DOI: 10.1016/J.Ccr.2010.02.027 |
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| 2010 |
Xu J, Dang Y, Ren YR, Liu JO. Cholesterol trafficking is required for mTOR activation in endothelial cells. Proceedings of the National Academy of Sciences of the United States of America. 107: 4764-9. PMID 20176935 DOI: 10.1073/Pnas.0910872107 |
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| 2010 |
Olaleye O, Raghunand TR, Bhat S, He J, Tyagi S, Lamichhane G, Gu P, Zhou J, Zhang Y, Grosset J, Bishai WR, Liu JO. Methionine aminopeptidases from Mycobacterium tuberculosis as novel antimycobacterial targets. Chemistry & Biology. 17: 86-97. PMID 20142044 DOI: 10.1016/J.Chembiol.2009.12.014 |
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| 2010 |
Schneider-Poetsch T, Ju J, Eyler DE, Dang Y, Bhat S, Merrick WC, Green R, Shen B, Liu JO. Inhibition of eukaryotic translation elongation by cycloheximide and lactimidomycin. Nature Chemical Biology. 6: 209-217. PMID 20118940 DOI: 10.1038/Nchembio.304 |
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Liu H, Shi W, Luan F, Xu S, Yang F, Sun W, Liu J, Ma C. Hepatitis B virus X protein upregulates transcriptional activation of human telomerase reverse transcriptase. Virus Genes. 40: 174-82. PMID 20107884 DOI: 10.1007/s11262-009-0441-3 |
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Zhang P, Wang C, Gao K, Wang D, Mao J, An J, Xu C, Wu D, Yu H, Liu JO, Yu L. The ubiquitin ligase itch regulates apoptosis by targeting thioredoxin-interacting protein for ubiquitin-dependent degradation. The Journal of Biological Chemistry. 285: 8869-79. PMID 20068034 DOI: 10.1074/Jbc.M109.063321 |
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Liu J, Someren E, Mentink A, Licht R, Dechering K, van Blitterswijk C, de Boer J. The effect of PKC activation and inhibition on osteogenic differentiation of human mesenchymal stem cells. Journal of Tissue Engineering and Regenerative Medicine. 4: 329-39. PMID 20033927 DOI: 10.1002/term.242 |
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Cheng K, Liu J, Sun H, Xie J. Synthesis of Nucleoside Conjugates as Potential Inhibitors of Glycogen Phosphorylase Synthesis. 2010: 1046-1052. DOI: 10.1055/S-0029-1218629 |
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Schneider-Poetsch T, Ju J, Eyler DE, Dang Y, Bhat S, Merrick WC, Green R, Shen B, Liu JO. Inhibition of eukaryotic translation elongation by cycloheximide and lactimidomycin Nature Chemical Biology. 6: 209-217. DOI: 10.1038/nchembio.304 |
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Zha XM, Zhang FR, Shan JQ, Zhang YH, Liu JO, Sun HB. Synthesis and evaluation of in vitro anticancer activity of novel solasodine derivatives Chinese Chemical Letters. 21: 1087-1090. DOI: 10.1016/J.Cclet.2010.04.020 |
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Olaleye OA, Bishai WR, Liu JO. Targeting the role of N-terminal methionine processing enzymes in Mycobacterium tuberculosis. Tuberculosis (Edinburgh, Scotland). 89: S55-9. PMID 20006307 DOI: 10.1016/S1472-9792(09)70013-7 |
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Yang HC, Xing S, Shan L, O'Connell K, Dinoso J, Shen A, Zhou Y, Shrum CK, Han Y, Liu JO, Zhang H, Margolick JB, Siliciano RF. Small-molecule screening using a human primary cell model of HIV latency identifies compounds that reverse latency without cellular activation. The Journal of Clinical Investigation. 119: 3473-86. PMID 19805909 DOI: 10.1172/Jci39199 |
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Lee K, Zhang H, Qian DZ, Rey S, Liu JO, Semenza GL. Acriflavine inhibits HIF-1 dimerization, tumor growth, and vascularization. Proceedings of the National Academy of Sciences of the United States of America. 106: 17910-5. PMID 19805192 DOI: 10.1073/Pnas.0909353106 |
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Li W, Dang Y, Liu JO, Yu B. Expeditious synthesis of hippuristanol and congeners with potent antiproliferative activities. Chemistry (Weinheim An Der Bergstrasse, Germany). 15: 10356-9. PMID 19746484 DOI: 10.1002/Chem.200901732 |
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Pan F, Yu H, Dang EV, Barbi J, Pan X, Grosso JF, Jinasena D, Sharma SM, McCadden EM, Getnet D, Drake CG, Liu JO, Ostrowski MC, Pardoll DM. Eos mediates Foxp3-dependent gene silencing in CD4+ regulatory T cells. Science (New York, N.Y.). 325: 1142-6. PMID 19696312 DOI: 10.1126/Science.1176077 |
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Ji L, Shen K, Liu J, Chen Y, Liu T, Wang Z. Intracellular glutathione regulates Andrographolide-induced cytotoxicity on hepatoma Hep3B cells. Redox Report : Communications in Free Radical Research. 14: 176-84. PMID 19695125 DOI: 10.1179/135100009X466122 |
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Zhang P, Hao J, Liu J, Lu Q, Sheng H, Zhang L, Sun H. Synthesis of 3-deoxypentacyclic triterpene derivatives as inhibitors of glycogen phosphorylase. Journal of Natural Products. 72: 1414-8. PMID 19642687 DOI: 10.1021/Np9002367 |
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Woodard LE, Chang W, Chen X, Liu JO, Shapiro TA, Posner GH. Malaria-infected mice live until at least day 30 after a new monomeric trioxane combined with mefloquine are administered together in a single low oral dose Journal of Medicinal Chemistry. 52: 7458-7462. PMID 19586052 DOI: 10.1021/Jm9005934 |
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Dang Y, Low WK, Xu J, Gehring NH, Dietz HC, Romo D, Liu JO. Inhibition of nonsense-mediated mRNA decay by the natural product pateamine A through eukaryotic initiation factor 4AIII. The Journal of Biological Chemistry. 284: 23613-21. PMID 19570977 DOI: 10.1074/Jbc.M109.009985 |
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Zhang Y, Byun Y, Ren YR, Liu JO, Laterra J, Pomper MG. Identification of inhibitors of ABCG2 by a bioluminescence imaging-based high-throughput assay Cancer Research. 69: 5867-5875. PMID 19567678 DOI: 10.1158/0008-5472.Can-08-4866 |
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Zou CY, Smith KD, Zhu QS, Liu J, McCutcheon IE, Slopis JM, Meric-Bernstam F, Peng Z, Bornmann WG, Mills GB, Lazar AJ, Pollock RE, Lev D. Dual targeting of AKT and mammalian target of rapamycin: a potential therapeutic approach for malignant peripheral nerve sheath tumor. Molecular Cancer Therapeutics. 8: 1157-68. PMID 19417153 DOI: 10.1158/1535-7163.Mct-08-1008 |
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Liu JO, Nacev BA, Xu J, Bhat S. It takes two binding sites for calcineurin and NFAT to tango. Molecular Cell. 33: 676-8. PMID 19328062 DOI: 10.1016/J.Molcel.2009.03.005 |
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Cheng K, Liu J, Liu X, Li H, Sun H, Xie J. Synthesis of glucoconjugates of oleanolic acid as inhibitors of glycogen phosphorylase. Carbohydrate Research. 344: 841-50. PMID 19269628 DOI: 10.1016/j.carres.2009.02.012 |
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Chen X, Xie S, Bhat S, Kumar N, Shapiro TA, Liu JO. Fumagillin and fumarranol interact with P. falciparum methionine aminopeptidase 2 and inhibit malaria parasite growth in vitro and in vivo. Chemistry & Biology. 16: 193-202. PMID 19246010 DOI: 10.1016/J.Chembiol.2009.01.006 |
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Wikoff WR, Anfora AT, Liu J, Schultz PG, Lesley SA, Peters EC, Siuzdak G. Metabolomics analysis reveals large effects of gut microflora on mammalian blood metabolites. Proceedings of the National Academy of Sciences of the United States of America. 106: 3698-703. PMID 19234110 DOI: 10.1073/Pnas.0812874106 |
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Rosenthal AS, Chen X, Liu JO, West DC, Hergenrother PJ, Shapiro TA, Posner GH. Malaria-infected mice are cured by a single oral dose of new dimeric trioxane sulfones which are also selectively and powerfully cytotoxic to cancer cells. Journal of Medicinal Chemistry. 52: 1198-203. PMID 19186946 DOI: 10.1021/Jm801484V |
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Lee K, Qian DZ, Rey S, Wei H, Liu JO, Semenza GL. Anthracycline chemotherapy inhibits HIF-1 transcriptional activity and tumor-induced mobilization of circulating angiogenic cells. Proceedings of the National Academy of Sciences of the United States of America. 106: 2353-8. PMID 19168635 DOI: 10.1073/Pnas.0812801106 |
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Ren YR, Pan F, Parvez S, Fleig A, Chong CR, Xu J, Dang Y, Zhang J, Jiang H, Penner R, Liu JO. Clofazimine inhibits human Kv1.3 potassium channel by perturbing calcium oscillation in T lymphocytes. Plos One. 3: e4009. PMID 19104661 DOI: 10.1371/Journal.Pone.0004009 |
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Zhang H, Qian DZ, Tan YS, Lee K, Gao P, Ren YR, Rey S, Hammers H, Chang D, Pili R, Dang CV, Liu JO, Semenza GL. Digoxin and other cardiac glycosides inhibit HIF-1α synthesis and block tumor growth Proceedings of the National Academy of Sciences of the United States of America. 105: 19579-19586. PMID 19020076 DOI: 10.1073/Pnas.0809763105 |
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Cheng K, Zhang P, Liu J, Xie J, Sun H. Practical synthesis of bredemolic acid, a natural inhibitor of glycogen phosphorylase. Journal of Natural Products. 71: 1877-80. PMID 18847277 DOI: 10.1021/Np8003886 |
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McMahon MA, Siliciano JD, Lai J, Liu JO, Stivers JT, Siliciano RF, Kohli RM. The antiherpetic drug acyclovir inhibits HIV replication and selects the V75I reverse transcriptase multidrug resistance mutation. The Journal of Biological Chemistry. 283: 31289-93. PMID 18818198 DOI: 10.1074/Jbc.C800188200 |
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Wang C, Jiang Z, Yao J, Wu X, Sun L, Liu C, Duan W, Yan M, Sun L, Liu J, Zhang L. Participation of cathepsin B in emodin-induced apoptosis in HK-2 Cells. Toxicology Letters. 181: 196-204. PMID 18789614 DOI: 10.1016/j.toxlet.2008.05.013 |
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Wang Y, Zhang F, Zhang Y, Liu JO, Ma D. Synthesis and antitumor activity of cyclodepsipeptide zygosporamide and its analogues. Bioorganic & Medicinal Chemistry Letters. 18: 4385-7. PMID 18606540 DOI: 10.1016/J.Bmcl.2008.06.066 |
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Wen X, Sun H, Liu J, Cheng K, Zhang P, Zhang L, Hao J, Zhang L, Ni P, Zographos SE, Leonidas DD, Alexacou KM, Gimisis T, Hayes JM, Oikonomakos NG. Naturally occurring pentacyclic triterpenes as inhibitors of glycogen phosphorylase: synthesis, structure-activity relationships, and X-ray crystallographic studies. Journal of Medicinal Chemistry. 51: 3540-54. PMID 18517260 DOI: 10.1021/Jm8000949 |
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Pei Y, Zhu P, Dang Y, Wu J, Yang X, Wan B, Liu JO, Yi Q, Yu L. Nuclear export of NF90 to stabilize IL-2 mRNA is mediated by AKT-dependent phosphorylation at Ser647 in response to CD28 costimulation. Journal of Immunology (Baltimore, Md. : 1950). 180: 222-9. PMID 18097023 DOI: 10.4049/Jimmunol.180.1.222 |
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Galbán S, Kuwano Y, Pullmann R, Martindale JL, Kim HH, Lal A, Abdelmohsen K, Yang X, Dang Y, Liu JO, Lewis SM, Holcik M, Gorospe M. RNA-binding proteins HuR and PTB promote the translation of hypoxia-inducible factor 1alpha. Molecular and Cellular Biology. 28: 93-107. PMID 17967866 DOI: 10.1128/Mcb.00973-07 |
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Liu J, Shi YH, Yin J, Gui JF. [Screen of differentially expressed genes between gastrula embryos and tail bud embryos in gynogenetic gibel carp (Carassius auratus gibelio)]. Yi Chuan Xue Bao = Acta Genetica Sinica. 32: 253-63. PMID 15931786 |
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Liu YV, Hubbi ME, Pan F, McDonald KR, Mansharamani M, Cole RN, Liu JO, Semenza GL. Calcineurin promotes hypoxia-inducible factor 1alpha expression by dephosphorylating RACK1 and blocking RACK1 dimerization. The Journal of Biological Chemistry. 282: 37064-73. PMID 17965024 DOI: 10.1074/Jbc.M705015200 |
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Yin J, Xia JH, Du XZ, Liu J, Zhou L, Hong YH, Gui JF. Developmental expression of CagMdkb during gibel carp embryogenesis. The International Journal of Developmental Biology. 51: 761-9. PMID 17939124 DOI: 10.1387/ijdb.072346jy |
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Hu XV, Chen X, Han KC, Mildvan AS, Liu JO. Kinetic and mutational studies of the number of interacting divalent cations required by bacterial and human methionine aminopeptidases. Biochemistry. 46: 12833-43. PMID 17929833 DOI: 10.1021/Bi701127X |
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Low WK, Dang Y, Schneider-Poetsch T, Shi Z, Choi NS, Rzasa RM, Shea HA, Li S, Park K, Ma G, Romo D, Liu JO. Isolation and identification of eukaryotic initiation factor 4A as a molecular target for the marine natural product Pateamine A. Methods in Enzymology. 431: 303-24. PMID 17923240 DOI: 10.1016/S0076-6879(07)31014-8 |
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Ji L, Liu T, Liu J, Chen Y, Wang Z. Andrographolide inhibits human hepatoma-derived Hep3B cell growth through the activation of c-Jun N-terminal kinase. Planta Medica. 73: 1397-401. PMID 17918040 DOI: 10.1055/s-2007-990230 |
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Peddibhotla S, Dang Y, Liu JO, Romo D. Simultaneous arming and structure/activity studies of natural products employing O-H insertions: an expedient and versatile strategy for natural products-based chemical genetics. Journal of the American Chemical Society. 129: 12222-31. PMID 17880073 DOI: 10.1021/Ja0733686 |
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Byrne ST, Gu P, Zhou J, Denkin SM, Chong C, Sullivan D, Liu JO, Zhang Y. Pyrrolidine dithiocarbamate and diethyldithiocarbamate are active against growing and nongrowing persister Mycobacterium tuberculosis. Antimicrobial Agents and Chemotherapy. 51: 4495-7. PMID 17876006 DOI: 10.1128/Aac.00753-07 |
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Peng W, Tang P, Hu X, Liu JO, Yu B. Synthesis of the A,B-ring-truncated OSW saponin analogs and their antitumor activities. Bioorganic & Medicinal Chemistry Letters. 17: 5506-9. PMID 17826089 DOI: 10.1016/J.Bmcl.2007.08.060 |
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Hu X, Dang Y, Tenney K, Crews P, Tsai CW, Sixt KM, Cole PA, Liu JO. Regulation of c-Src Nonreceptor Tyrosine Kinase Activity by Bengamide A through Inhibition of Methionine Aminopeptidases Chemistry and Biology. 14: 764-774. PMID 17656313 DOI: 10.1016/J.Chembiol.2007.05.010 |
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Zhao Q, Liu Z, Wang Z, Yang C, Liu J, Lu J. Effect of prepro-calcitonin gene-related peptide-expressing endothelial progenitor cells on pulmonary hypertension. The Annals of Thoracic Surgery. 84: 544-52. PMID 17643632 DOI: 10.1016/J.ATHORACSUR.2007.03.067 |
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Low WK, Dang Y, Bhat S, Romo D, Liu JO. Substrate-dependent targeting of eukaryotic translation initiation factor 4A by pateamine A: negation of domain-linker regulation of activity. Chemistry & Biology. 14: 715-27. PMID 17584618 DOI: 10.1016/J.Chembiol.2007.05.012 |
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McMahon MA, Jilek BL, Brennan TP, Shen L, Zhou Y, Wind-Rotolo M, Xing S, Bhat S, Hale B, Hegarty R, Chong CR, Liu JO, Siliciano RF, Thio CL. The HBV drug entecavir - effects on HIV-1 replication and resistance. The New England Journal of Medicine. 356: 2614-21. PMID 17582071 DOI: 10.1056/Nejmoa067710 |
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Chong CR, Xu J, Lu J, Bhat S, Sullivan DJ, Liu JO. Inhibition of angiogenesis by the antifungal drug itraconazole. Acs Chemical Biology. 2: 263-70. PMID 17432820 DOI: 10.1021/Cb600362D |
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Fang K, Fu W, Beardsley AR, Sun X, Lisanti MP, Liu J. Overexpression of caveolin-1 inhibits endothelial cell proliferation by arresting the cell cycle at G0/G1 phase. Cell Cycle (Georgetown, Tex.). 6: 199-204. PMID 17245131 DOI: 10.4161/Cc.6.2.3740 |
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Pan F, Sun L, Kardian DB, Whartenby KA, Pardoll DM, Liu JO. Feedback inhibition of calcineurin and Ras by a dual inhibitory protein Carabin. Nature. 445: 433-6. PMID 17230191 DOI: 10.1038/Nature05476 |
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Tang P, Mamdani F, Hu X, Liu JO, Yu B. Synthesis of OSW saponin analogs with modified sugar residues and their antiproliferative activities. Bioorganic & Medicinal Chemistry Letters. 17: 1003-7. PMID 17127060 DOI: 10.1016/J.Bmcl.2006.11.032 |
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Hu X, Mildvan AS, Liu JO. Cooperative activation of human mitochondrial Methionine Aminopeptidase (hmMetAP) by Co2+ The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A272-B |
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Allen MD, DiPilato LM, Rahdar M, Ren YR, Chong C, Liu JO, Zhang J. Reading dynamic kinase activity in living cells for high-throughput screening. Acs Chemical Biology. 1: 371-6. PMID 17163774 DOI: 10.1021/Cb600202F |
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Hu X, Addlagatta A, Lu J, Matthews BW, Liu JO. Elucidation of the function of type 1 human methionine aminopeptidase during cell cycle progression. Proceedings of the National Academy of Sciences of the United States of America. 103: 18148-53. PMID 17114291 DOI: 10.1073/Pnas.0608389103 |
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Zhou M, Sivaramakrishnan A, Ponnamperuma K, Low WK, Li C, Liu JO, Bergbreiter DE, Romo D. Synthesis, characterization, and utility of thermoresponsive natural/unnatural product macroligands for affinity chromatography. Organic Letters. 8: 5247-50. PMID 17078689 DOI: 10.1021/Ol062045W |
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Chen X, Chong CR, Shi L, Yoshimoto T, Sullivan DJ, Liu JO. Inhibitors of Plasmodium falciparum methionine aminopeptidase 1b possess antimalarial activity. Proceedings of the National Academy of Sciences of the United States of America. 103: 14548-53. PMID 16983082 DOI: 10.1073/Pnas.0604101103 |
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Lu J, Chong CR, Hu X, Liu JO. Fumarranol, a rearranged fumagillin analogue that inhibits angiogenesis in vivo. Journal of Medicinal Chemistry. 49: 5645-8. PMID 16970390 DOI: 10.1021/Jm060559V |
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Dang Y, Kedersha N, Low WK, Romo D, Gorospe M, Kaufman R, Anderson P, Liu JO. Eukaryotic initiation factor 2alpha-independent pathway of stress granule induction by the natural product pateamine A. The Journal of Biological Chemistry. 281: 32870-8. PMID 16951406 DOI: 10.1074/Jbc.M606149200 |
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Kim H, Kim BY, Soh JW, Cho EJ, Liu JO, Youn HD. A novel function of Nur77: physical and functional association with protein kinase C. Biochemical and Biophysical Research Communications. 348: 950-6. PMID 16904076 DOI: 10.1016/J.Bbrc.2006.07.167 |
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Ma D, Zou B, Cai G, Hu X, Liu JO. Total synthesis of the cyclodepsipeptide apratoxin A and its analogues and assessment of their biological activities. Chemistry (Weinheim An Der Bergstrasse, Germany). 12: 7615-26. PMID 16832801 DOI: 10.1002/Chem.200600599 |
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Chong CR, Chen X, Shi L, Liu JO, Sullivan DJ. A clinical drug library screen identifies astemizole as an antimalarial agent. Nature Chemical Biology. 2: 415-6. PMID 16816845 DOI: 10.1038/Nchembio806 |
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Hu X, Addlagatta A, Matthews BW, Liu JO. Identification of pyridinylpyrimidines as inhibitors of human methionine aminopeptidases. Angewandte Chemie (International Ed. in English). 45: 3772-5. PMID 16724298 DOI: 10.1002/Anie.200600757 |
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Chong CR, Qian DZ, Pan F, Wei Y, Pili R, Sullivan DJ, Liu JO. Identification of type 1 inosine monophosphate dehydrogenase as an antiangiogenic drug target. Journal of Medicinal Chemistry. 49: 2677-80. PMID 16640327 DOI: 10.1021/Jm051225T |
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Hu X, Addlagatta A, Matthews BW, Liu JO. Cover Picture: Identification of Pyridinylpyrimidines as Inhibitors of Human Methionine Aminopeptidases (Angew. Chem. Int. Ed. 23/2006) Angewandte Chemie International Edition. 45: 3717-3717. DOI: 10.1002/Anie.200690079 |
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Hu X, Addlagatta A, Matthews BW, Liu JO. Titelbild: Identification of Pyridinylpyrimidines as Inhibitors of Human Methionine Aminopeptidases (Angew. Chem. 23/2006) Angewandte Chemie. 118: 3801-3801. DOI: 10.1002/Ange.200690079 |
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Low WK, Dang Y, Schneider-Poetsch T, Shi Z, Choi NS, Merrick WC, Romo D, Liu JO. Inhibition of eukaryotic translation initiation by the marine natural product pateamine A. Molecular Cell. 20: 709-22. PMID 16337595 DOI: 10.1016/J.Molcel.2005.10.008 |
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Shi B, Tang P, Hu X, Liu JO, Yu B. OSW saponins: facile synthesis toward a new type of structures with potent antitumor activities. The Journal of Organic Chemistry. 70: 10354-67. PMID 16323845 DOI: 10.1021/Jo051536B |
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Addlagatta A, Hu X, Liu JO, Matthews BW. Structural basis for the functional differences between type I and type II human methionine aminopeptidases. Biochemistry. 44: 14741-9. PMID 16274222 DOI: 10.1021/Bi051691K |
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Burguière A, Hitchen PG, Dover LG, Kremer L, Ridell M, Alexander DC, Liu J, Morris HR, Minnikin DE, Dell A, Besra GS. LosA, a key glycosyltransferase involved in the biosynthesis of a novel family of glycosylated acyltrehalose lipooligosaccharides from Mycobacterium marinum. The Journal of Biological Chemistry. 280: 42124-33. PMID 16257960 DOI: 10.1074/Jbc.M507500200 |
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Pan F, Means AR, Liu JO. Calmodulin-dependent protein kinase IV regulates nuclear export of Cabin1 during T-cell activation. The Embo Journal. 24: 2104-13. PMID 15902271 DOI: 10.1038/Sj.Emboj.7600685 |
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Addlagatta A, Quillin ML, Omotoso O, Liu JO, Matthews BW. Identification of an SH3-binding motif in a new class of methionine aminopeptidases from Mycobacterium tuberculosis suggests a mode of interaction with the ribosome. Biochemistry. 44: 7166-74. PMID 15882055 DOI: 10.1021/Bi0501176 |
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Wang S, Dong Y, Wang X, Hu X, Liu JO, Hu Y. 3-Aryl beta-carbolin-1-ones as a new class of potent inhibitors of tumor cell proliferation: synthesis and biological evaluation. Organic & Biomolecular Chemistry. 3: 911-6. PMID 15731878 DOI: 10.1039/B412921K |
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Liu J, Wu X, Mitchell B, Kintner C, Ding S, Schultz PG. A small-molecule agonist of the Wnt signaling pathway. Angewandte Chemie (International Ed. in English). 44: 1987-90. PMID 15724259 DOI: 10.1002/Anie.200462552 |
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Liu J, Bang AG, Kintner C, Orth AP, Chanda SK, Ding S, Schultz PG. Identification of the Wnt signaling activator leucine-rich repeat in Flightless interaction protein 2 by a genome-wide functional analysis. Proceedings of the National Academy of Sciences of the United States of America. 102: 1927-32. PMID 15677333 DOI: 10.1073/Pnas.0409472102 |
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Liu JO. The yins of T cell activation. Science's Stke : Signal Transduction Knowledge Environment. 2005: re1. PMID 15632417 DOI: 10.1126/stke.2652005re1 |
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Han A, He J, Wu Y, Liu JO, Chen L. Mechanism of recruitment of class II histone deacetylases by myocyte enhancer factor-2. Journal of Molecular Biology. 345: 91-102. PMID 15567413 DOI: 10.1016/J.Jmb.2004.10.033 |
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| 2004 |
Boxem M, Tsai CW, Zhang Y, Saito RM, Liu JO. The C. elegans methionine aminopeptidase 2 analog map-2 is required for germ cell proliferation. Febs Letters. 576: 245-50. PMID 15474045 DOI: 10.1016/J.Febslet.2004.08.077 |
0.341 |
|
| 2004 |
Romo D, Choi NS, Li S, Buchler I, Shi Z, Liu JO. Evidence for separate binding and scaffolding domains in the immunosuppressive and antitumor marine natural product, pateamine a: design, synthesis, and activity studies leading to a potent simplified derivative. Journal of the American Chemical Society. 126: 10582-8. PMID 15327314 DOI: 10.1021/Ja040065S |
0.607 |
|
| 2004 |
Wang S, Sun J, Yu G, Hu X, Liu JO, Hu Y. CuI catalyzed N-arylation of amide as a key step for the preparation of 3-aryl beta-carbolin-1-ones. Organic & Biomolecular Chemistry. 2: 1573-4. PMID 15162205 DOI: 10.1039/B406046F |
0.456 |
|
| 2004 |
Lu SC, Yan LN, Li B, Wen TF, Zhao JC, Cheng NS, Liu C, Liu J, Wang XB, Li XD, Qin S, Zhao LS, Lei BJ, Zhang XH. Lamivudine prophylaxis of liver allograft HBV reinfection in HBV related cirrhotic patients after liver transplantation. Hepatobiliary & Pancreatic Diseases International : Hbpd Int. 3: 26-32. PMID 14969833 |
0.327 |
|
| 2004 |
Alexander DC, Jones JR, Tan T, Chen JM, Liu J. PimF, a mannosyltransferase of mycobacteria, is involved in the biosynthesis of phosphatidylinositol mannosides and lipoarabinomannan. The Journal of Biological Chemistry. 279: 18824-33. PMID 14960574 DOI: 10.1074/Jbc.M400791200 |
0.375 |
|
| 2004 |
Choi JW, Park SC, Kang GH, Liu JO, Youn HD. Nur77 activated by hypoxia-inducible factor-1alpha overproduces proopiomelanocortin in von Hippel-Lindau-mutated renal cell carcinoma. Cancer Research. 64: 35-9. PMID 14729605 DOI: 10.1158/0008-5472.Can-03-0145 |
0.631 |
|
| 2004 |
Pan F, Ye Z, Cheng L, Liu JO. Myocyte enhancer factor 2 mediates calcium-dependent transcription of the interleukin-2 gene in T lymphocytes: a calcium signaling module that is distinct from but collaborates with the nuclear factor of activated T cells (NFAT). The Journal of Biological Chemistry. 279: 14477-80. PMID 14722108 DOI: 10.1074/Jbc.C300487200 |
0.592 |
|
| 2004 |
Zheng L, Liu J, Batalov S, Zhou D, Orth A, Ding S, Schultz PG. An approach to genomewide screens of expressed small interfering RNAs in mammalian cells. Proceedings of the National Academy of Sciences of the United States of America. 101: 135-40. PMID 14688408 DOI: 10.1073/Pnas.2136685100 |
0.423 |
|
| 2003 |
Liu JO. Endogenous protein inhibitors of calcineurin. Biochemical and Biophysical Research Communications. 311: 1103-9. PMID 14623296 DOI: 10.1016/J.Bbrc.2003.10.020 |
0.406 |
|
| 2003 |
Kim H, Lee JE, Cho EJ, Liu JO, Youn HD. Menin, a tumor suppressor, represses JunD-mediated transcriptional activity by association with an mSin3A-histone deacetylase complex. Cancer Research. 63: 6135-9. PMID 14559791 |
0.595 |
|
| 2003 |
Zhou G, Tsai CW, Liu JO. Fumagalone, a reversible inhibitor of type 2 methionine aminopeptidase and angiogenesis. Journal of Medicinal Chemistry. 46: 3452-4. PMID 12877582 DOI: 10.1021/Jm0341103 |
0.412 |
|
| 2003 |
Nezami A, Kimura T, Hidaka K, Kiso A, Liu J, Kiso Y, Goldberg DE, Freire E. High-affinity inhibition of a family of Plasmodium falciparum proteases by a designed adaptive inhibitor. Biochemistry. 42: 8459-64. PMID 12859191 DOI: 10.1021/Bi034131Z |
0.334 |
|
| 2003 |
He H, Dang Y, Dai F, Guo Z, Wu J, She X, Pei Y, Chen Y, Ling W, Wu C, Zhao S, Liu JO, Yu L. Post-translational modifications of three members of the human MAP1LC3 family and detection of a novel type of modification for MAP1LC3B. The Journal of Biological Chemistry. 278: 29278-87. PMID 12740394 DOI: 10.1074/Jbc.M303800200 |
0.629 |
|
| 2003 |
Han A, Pan F, Stroud JC, Youn HD, Liu JO, Chen L. Sequence-specific recruitment of transcriptional co-repressor Cabin1 by myocyte enhancer factor-2. Nature. 422: 730-4. PMID 12700764 DOI: 10.1038/Nature01555 |
0.727 |
|
| 2003 |
Visner GA, Lu F, Zhou H, Liu J, Kazemfar K, Agarwal A. Rapamycin induces heme oxygenase-1 in human pulmonary vascular cells: implications in the antiproliferative response to rapamycin. Circulation. 107: 911-6. PMID 12591764 DOI: 10.1161/01.Cir.0000048191.75585.60 |
0.303 |
|
| 2003 |
Guo WZ, Ran YL, Liu J, Yu L, Sun LX, Yang ZH. [High expression of human angiogenesis inhibitor HIAF-1 in insect cells and biological activity]. Ai Zheng = Aizheng = Chinese Journal of Cancer. 21: 245-8. PMID 12451987 |
0.326 |
|
| 2002 |
Huai Q, Kim HY, Liu Y, Zhao Y, Mondragon A, Liu JO, Ke H. Crystal structure of calcineurin-cyclophilin-cyclosporin shows common but distinct recognition of immunophilin-drug complexes. Proceedings of the National Academy of Sciences of the United States of America. 99: 12037-42. PMID 12218175 DOI: 10.1073/Pnas.192206699 |
0.753 |
|
| 2002 |
Kim MJ, Jo DG, Hong GS, Kim BJ, Lai M, Cho DH, Kim KW, Bandyopadhyay A, Hong YM, Kim DH, Cho C, Liu JO, Snyder SH, Jung YK. Calpain-dependent cleavage of cain/cabin1 activates calcineurin to mediate calcium-triggered cell death. Proceedings of the National Academy of Sciences of the United States of America. 99: 9870-5. PMID 12114545 DOI: 10.1073/Pnas.152336999 |
0.396 |
|
| 2002 |
Smulik JA, Diver ST, Pan F, Liu JO. Synthesis of cyclosporin A-derived affinity reagents by olefin metathesis. Organic Letters. 4: 2051-4. PMID 12049515 DOI: 10.1021/Ol0258987 |
0.7 |
|
| 2001 |
Esau C, Boes M, Youn HD, Tatterson L, Liu JO, Chen J. Deletion of calcineurin and myocyte enhancer factor 2 (MEF2) binding domain of Cabin1 results in enhanced cytokine gene expression in T cells Journal of Experimental Medicine. 194: 1449-1459. PMID 11714752 DOI: 10.1084/Jem.194.10.1449 |
0.621 |
|
| 2001 |
Baumgrass R, Weiwad M, Erdmann F, Liu JO, Wunderlich D, Grabley S, Fischer G. Reversible Inhibition of Calcineurin by the Polyphenolic Aldehyde Gossypol Journal of Biological Chemistry. 276: 47914-47921. PMID 11598106 DOI: 10.1074/Jbc.M103273200 |
0.432 |
|
| 2001 |
Zhang LH, Youn HD, Liu JO. Inhibition of Cell Cycle Progression by the Novel Cyclophilin Ligand Sanglifehrin A Is Mediated through the NFκB-dependent Activation of p53 Journal of Biological Chemistry. 276: 43534-43540. PMID 11557753 DOI: 10.1074/Jbc.M104257200 |
0.665 |
|
| 2001 |
Liu W, Youn HD, Liu JO. Thapsigargin-induced apoptosis involves Cabin1-MEF2-mediated induction of Nur77 European Journal of Immunology. 31: 1757-1764. PMID 11385620 DOI: 10.1002/1521-4141(200106)31:6<1757::Aid-Immu1757>3.0.Co;2-J |
0.697 |
|
| 2001 |
Liu W, Youn HD, Zhou XZ, Lu KP, Liu JO. Binding and regulation of the transcription factor NFAT by the peptidyl prolyl cis-trans isomerase Pin1 Febs Letters. 496: 105-108. PMID 11356192 DOI: 10.1016/S0014-5793(01)02411-5 |
0.703 |
|
| 2001 |
Zhang LH, Liu JO. Sanglifehrin A, a novel cyclophilin-binding immunosuppressant, inhibits IL-2-dependent T cell proliferation at the G1 phase of the cell cycle Journal of Immunology. 166: 5611-5618. PMID 11313401 DOI: 10.4049/Jimmunol.166.9.5611 |
0.757 |
|
| 2000 |
Youn HD, Chatila TA, Liu JO. Integration of calcineurin and MEF2 signals by the coactivator p300 during T-cell apoptosis Embo Journal. 19: 4323-4331. PMID 10944115 DOI: 10.1093/Emboj/19.16.4323 |
0.644 |
|
| 2000 |
Youn HD, Liu JO. Cabin1 represses MEF2-dependent Nur77 expression and T cell apoptosis by controlling association of histone deacetylases and acetylases with MEF2 Immunity. 13: 85-94. PMID 10933397 DOI: 10.1016/S1074-7613(00)00010-8 |
0.608 |
|
| 2000 |
Zhang Y, Griffith EC, Sage J, Jacks T, Liu JO. Cell cycle inhibition by the anti-angiogenic agent TNP-470 is mediated by p53 and p21WAF1/CIP1. Proceedings of the National Academy of Sciences of the United States of America. 97: 6427-32. PMID 10841547 DOI: 10.1073/Pnas.97.12.6427 |
0.397 |
|
| 2000 |
Youn HD, Grozinger CM, Liu JO. Calcium regulates transcriptional repression of myocyte enhancer factor 2 by histone deacetylase 4. The Journal of Biological Chemistry. 275: 22563-7. PMID 10825153 DOI: 10.1074/Jbc.C000304200 |
0.711 |
|
| 2000 |
Dai X, Su Z, Liu JO. An improved synthesis of a selective αvβ3-integrin antagonist cyclo(-RGDfK-) Tetrahedron Letters. 41: 6295-6298. |
0.745 |
|
| 1999 |
Turk BE, Griffith EC, Wolf S, Biemann K, Chang YH, Liu JO. Selective inhibition of amino-terminal methionine processing by TNP-470 and ovalicin in endothelial cells. Chemistry & Biology. 6: 823-33. PMID 10574784 DOI: 10.1016/S1074-5521(99)80129-X |
0.638 |
|
| 1999 |
Youn HD, Sun L, Prywes R, Liu JO. Apoptosis of T cells mediated by Ca2+-induced release of the transcription factor MEF2. Science (New York, N.Y.). 286: 790-3. PMID 10531067 DOI: 10.1126/Science.286.5440.790 |
0.791 |
|
| 1998 |
Niwayama S, Loh C, Turk BE, Liu JO, Miyachi H, Hashimoto Y. Enhanced potency of perfluorinated thalidomide derivatives for inhibition of LPS-induced tumor necrosis factor-α production is associated with a change of mechanism of action Bioorganic and Medicinal Chemistry Letters. 8: 1071-1076. PMID 9871710 DOI: 10.1016/S0960-894X(98)00171-1 |
0.799 |
|
| 1998 |
Griffith EC, Zhuang SU, Niwayama S, Ramsay CA, Chang YH, Liu JO. Molecular recognition of angiogenesis inhibitors fumagillin and ovalicin by methionine aminopeptidase 2 Proceedings of the National Academy of Sciences of the United States of America. 95: 15183-15188. PMID 9860943 DOI: 10.1073/Pnas.95.26.15183 |
0.699 |
|
| 1998 |
Turk BE, Su Z, Liu JO. Synthetic analogues of TNP-470 and ovalicin reveal a common molecular basis for inhibition of angiogenesis and immunosuppression Bioorganic and Medicinal Chemistry. 6: 1163-1169. PMID 9784858 DOI: 10.1016/S0968-0896(98)00078-9 |
0.842 |
|
| 1998 |
Miyachi H, Koiso Y, Shirai R, Niwayama S, Liu JO, Hashimoto Y. Tumor necrosis factor-alpha production enhancing activity of substituted 3'-methylthalidomide: Influence of substituents at the phthaloyl moiety on the activity and stereoselectivity Chemical and Pharmaceutical Bulletin. 46: 1165-1168. PMID 9692223 DOI: 10.1248/Cpb.46.1165 |
0.624 |
|
| 1998 |
Sun L, Youn HD, Loh C, Stolow M, He W, Liu JO. Cabin 1, a negative regulator for calcineurin signaling in T lymphocytes Immunity. 8: 703-711. PMID 9655484 DOI: 10.1016/S1074-7613(00)80575-0 |
0.811 |
|
| 1998 |
Romo D, Rzasa RM, Shea HA, Park K, Langenhan JM, Sun L, Akhiezer A, Liu JO. Total synthesis and immunosuppressive activity of (-)-pateamine A and related compounds: Implementation of a β-lactam-based macrocyclization Journal of the American Chemical Society. 120: 12237-12254. DOI: 10.1021/Ja981846U |
0.55 |
|
| 1997 |
Jiang H, Xiong F, Kong S, Ogawa T, Kobayashi M, Liu JO. Distinct tissue and cellular distribution of two major isoforms of calcineurin Molecular Immunology. 34: 663-669. PMID 9393969 DOI: 10.1016/S0161-5890(97)00054-0 |
0.33 |
|
| 1997 |
Griffith EC, Su Z, Turk BE, Chen S, Chang YH, Wu Z, Biemann K, Liu JO. Methionine aminopeptidase (type 2) is the common target for angiogenesis inhibitors AGM-1470 and ovalicin. Chemistry & Biology. 4: 461-71. PMID 9224570 DOI: 10.1016/S1074-5521(97)90198-8 |
0.847 |
|
| 1997 |
Mondragon A, Griffith EC, Sun L, Xiong F, Armstrong C, Liu JO. Overexpression and purification of human calcineurin alpha from Escherichia coli and assessment of catalytic functions of residues surrounding the binuclear metal center. Biochemistry. 36: 4934-42. PMID 9125515 DOI: 10.1021/Bi9631935 |
0.731 |
|
| 1996 |
Niwayama S, Turk BE, Liu JO. Potent inhibition of tumor necrosis factor-α production by tetrafluorothalidomide and tetrafluorophthalimides Journal of Medicinal Chemistry. 39: 3044-3045. PMID 8759624 DOI: 10.1021/Jm960284R |
0.728 |
|
| 1996 |
Turk BE, Jiang H, Liu JO. Binding of thalidomide to α1-acid glycoprotein may be involved in its inhibition of tumor necrosis factor α production Proceedings of the National Academy of Sciences of the United States of America. 93: 7552-7556. PMID 8755512 DOI: 10.1073/Pnas.93.15.7552 |
0.617 |
|
| 1994 |
Liu J. Microcin B17: Posttranslational modifications and their biological implications Proceedings of the National Academy of Sciences of the United States of America. 91: 4618-4620. PMID 8197107 DOI: 10.1073/Pnas.91.11.4618 |
0.351 |
|
| 1993 |
Liu J. FK506 and ciclosporin: molecular probes for studying intracellular signal transduction Trends in Pharmacological Sciences. 14: 182-188. PMID 7692652 DOI: 10.1016/0165-6147(93)90206-Y |
0.376 |
|
| 1992 |
Liu J, Albers MW, Wandless TJ, Luan S, Alberg DG, Belshaw PJ, Cohen P, MacKintosh C, Klee CB, Schreiber SL. Inhibition of T cell signaling by immunophilin-ligand complexes correlates with loss of calcineurin phosphatase activity. Biochemistry. 31: 3896-901. PMID 1373650 DOI: 10.1021/Bi00131A002 |
0.813 |
|
| 1991 |
Liu J, Farmer JD, Lane WS, Friedman J, Weissman I, Schreiber SL. Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes. Cell. 66: 807-15. PMID 1715244 DOI: 10.1016/0092-8674(91)90124-H |
0.512 |
|
| 1990 |
Liu J, Albers MW, Chen CM, Schreiber SL, Walsh CT. Cloning, expression, and purification of human cyclophilin in Escherichia coli and assessment of the catalytic role of cysteines by site-directed mutagenesis. Proceedings of the National Academy of Sciences of the United States of America. 87: 2304-8. PMID 2179953 DOI: 10.1073/Pnas.87.6.2304 |
0.576 |
|
| 1990 |
Liu J, Quinn N, Berchtold GA, Walsh CT. Overexpression, purification, and characterization of isochorismate synthase (EntC), the first enzyme involved in the biosynthesis of enterobactin from chorismate. Biochemistry. 29: 1417-25. PMID 2139795 DOI: 10.1021/Bi00458A012 |
0.433 |
|
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